CN208270290U - A kind of whole blood blood plasma automatic separating apparatus - Google Patents
A kind of whole blood blood plasma automatic separating apparatus Download PDFInfo
- Publication number
- CN208270290U CN208270290U CN201820702517.9U CN201820702517U CN208270290U CN 208270290 U CN208270290 U CN 208270290U CN 201820702517 U CN201820702517 U CN 201820702517U CN 208270290 U CN208270290 U CN 208270290U
- Authority
- CN
- China
- Prior art keywords
- blood
- blood plasma
- whole blood
- disengagement chamber
- rotating disk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000002381 plasma Anatomy 0.000 title claims abstract description 39
- 210000004369 blood Anatomy 0.000 claims abstract description 33
- 239000008280 blood Substances 0.000 claims abstract description 33
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 29
- 210000003743 erythrocyte Anatomy 0.000 claims abstract description 20
- 238000004321 preservation Methods 0.000 claims description 13
- 238000005452 bending Methods 0.000 claims description 9
- 230000007246 mechanism Effects 0.000 claims description 4
- 238000001514 detection method Methods 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 6
- 238000000926 separation method Methods 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 238000003759 clinical diagnosis Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004452 microanalysis Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 238000010183 spectrum analysis Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Abstract
The utility model relates to a kind of whole blood blood plasma automatic separating apparatus comprising rotating disk, the blood vessel out into blood vessel and for conveying blood plasma for being used to convey whole blood that disengagement chamber on the rotating pan is arranged and is connected respectively with disengagement chamber;The utility model uses disc centrifuge structure, whole blood is separated in disengagement chamber, since blood plasma is lighter, red blood cell is heavier, and rotating disk generates centrifugal force by rotation, under the influence of centrifugal force, heavier red blood cell is located at the outboard end of disengagement chamber, and lighter blood plasma is located at the inner end of disengagement chamber, and blood plasma separation is then transported to next process by going out blood vessel and carries out detection or mixes in other reagents, realization is automatically separated and conveys, and uses simpler convenience.
Description
Technical field
The utility model relates to testing equipment fields, and in particular to a kind of whole blood blood plasma automatic separating apparatus.
Background technique
Blood testing is biomedicine, clinical diagnosis, most commonly used pattern detection in health quarantine diagnosis, but red thin
There is very big interference to the spectrum analysis in blood testing in the presence of born of the same parents, therefore how quickly and easily to isolate from whole blood
Serum is always the hot spot and difficulties of blood testing research.
Overwhelming majority hospital and laboratory still use super-magnum centrifuge separation serum and haemocyte at present, and the method needs
The blood sample of milliliter amount is collected from patient's body, and really only several microlitres of sample for detection, lead to a large amount of of sample
Waste.And such centrifugation apparatus volume is big, complicated in mechanical structure, and serum separation process and detection are to be separated and independently performed, easily
Cause the loss and pollution of blood sample, be not suitable for the integrated of clinical diagnosis and micro-analysis system, at the same detecting step compared with
For complexity.
Utility model content
The technical problem to be solved by the utility model is to provide it is a kind of based on centrifugal force quickly by the blood plasma in whole blood from
Dynamic isolated whole blood blood plasma automatic separating apparatus.
The technical scheme adopted by the utility model is a kind of whole blood blood plasma automatic separating apparatus comprising rotating disk is set
Set disengagement chamber on the rotating pan and be connected respectively with disengagement chamber for convey whole blood into blood vessel and for conveying blood
Slurry goes out blood vessel.
Rotating disk described in the utility model is rounded, in being provided centrally with for rotating disc spins with driving for rotating disk
The centre bore that rotating mechanism is connected.
The other end described in the utility model into blood vessel is connected with whole blood chamber, the maximum of the whole blood chamber and axis of rotation
Distance is less than the minimum range of disengagement chamber and axis of rotation.
Disengagement chamber described in the utility model is divided into Erythrocyte preservation portion and blood plasma reservoir, and Erythrocyte preservation portion is located at blood
The outside of reservoir is starched, described to be connected into blood vessel with Erythrocyte preservation portion, the blood vessel out is connected with blood plasma reservoir.
The volumetric ratio of Erythrocyte preservation portion described in the utility model and blood plasma reservoir is 2:3.
Disengagement chamber described in the utility model is arranged radially along rotating disk.
The utility model it is described go out blood vessel on be provided with bending part, the rotation center of the bending part and rotating disk away from
From the minimum range for being less than disengagement chamber and rotation center.
The utility model is provided with adding hole on the whole blood chamber.
The good effect of the utility model are as follows: the utility model uses disc centrifuge structure, and whole blood carries out in disengagement chamber
Separation, since blood plasma is lighter, red blood cell is heavier, and rotating disk generates centrifugal force by rotation, under the influence of centrifugal force, heavier
Red blood cell is located at the outboard end of disengagement chamber, and lighter blood plasma is located at the inner end of disengagement chamber, then by going out blood vessel for blood plasma point
It carries out detection from next process is transported to or is mixed in other reagents, using simpler convenience, realize automatic point
From with conveying.
Detailed description of the invention
FIG. 1 is a schematic structural view of the utility model.
In the accompanying drawings, 1- rotating disk, 2- are into blood vessel, 3- whole blood chamber, 4- adding hole, 5- disengagement chamber, 501- Erythrocyte preservation
Portion, 502- blood plasma reservoir, 6- go out blood vessel, 7- center line, 8- bending part.
Specific embodiment
As shown in Fig. 1, the utility model include rotating disk 1, the disengagement chamber being arranged in rotating disk 15 and respectively with
Blood vessel 6, the rotating disk 1 out into blood vessel 2 and for conveying blood plasma for conveying whole blood that disengagement chamber 5 is connected are mounted on rotation
In mechanism, rotating disk 1 is driven to be rotated under the action of rotating mechanism, it is preferred that rotating disk 1 uses circle, rotating disk 1
The center of circle is that axle center is rotated.
The other end into blood vessel 2 is connected with whole blood chamber 3, there is the adding hole for whole blood to be added on whole blood chamber 3
4, the whole blood chamber 3 is less than the minimum range of disengagement chamber 5 and axis of rotation with the maximum distance of axis of rotation.Whole blood is added to
In whole blood chamber 3, under the action of rotating disk 1 rotates, whole blood is entered in disengagement chamber 5 into blood vessel 2, is centrifuged.Phase
For disengagement chamber 5, whole blood chamber 3 is closer apart from axis of rotation, and whole blood can be effectively ensured in this way can smoothly enter into disengagement chamber 5
It is interior.
Since blood plasma is lighter, red blood cell is heavier, under the influence of centrifugal force, Erythrocyte preservation portion is formed in disengagement chamber
501 and blood plasma reservoir 502, Erythrocyte preservation portion 501 is greater than in blood plasma reservoir 502 and rotation at a distance from rotation center
The distance of the heart.Since red blood cell accounts for about the 40% of whole blood, the volumetric ratio of Erythrocyte preservation portion and blood plasma reservoir is limited as 2:3, into
Blood vessel 2 is connected with Erythrocyte preservation portion, and the blood vessel 6 out is connected with blood plasma reservoir, can be effectively ensured from blood vessel 6 out
Discharge is blood plasma, will not adulterate red blood cell, guarantees accuracy in detection.
The disengagement chamber 5 passes through along the center line 7 that rotating disk 1 is arranged radially i.e. disengagement chamber 5 in the upright projection of rotating disk 1
The rotation center of rotating disk 1, helps to ensure that centrifugal effect.
It is provided with bending part 8 on the blood vessel 6 out, the bending part 8 is less than at a distance from the rotation center of rotating disk 1
The minimum range of disengagement chamber 5 and rotation center.Bending part 8 is closer apart from rotation center, and liquid needs bigger pressure just can be with
By the bending part 8 then into next process, whole blood residence time in disengagement chamber 5 can be extended, be sufficiently centrifuged
Separation, separating effect is very good, guarantees only have blood plasma that can just be discharged from blood vessel 6 out.
The utility model go out blood vessel 6 can connecting detection chamber, test chamber is similarly positioned in rotating disk 1, straight by going out blood vessel 6
Switch through shifting, avoid the loss and pollution of blood sample, is suitable for the detection methods such as scattering, transmission, fluorescence, chemical method.
Above embodiments are only to illustrate the technical solution of the utility model, rather than its limitations;Although referring to aforementioned reality
Example is applied the utility model is described in detail, those skilled in the art should understand that: it still can be to preceding
Technical solution documented by embodiment is stated to modify or equivalent replacement of some of the technical features;And these are repaired
Change or replaces, the spirit and scope for the utility model embodiment technical solution that it does not separate the essence of the corresponding technical solution.
Claims (8)
1. a kind of whole blood blood plasma automatic separating apparatus, it is characterised in that it includes rotating disk (1), is arranged on rotating disk (1)
Disengagement chamber (5) and be connected respectively with disengagement chamber (5) for convey whole blood into blood vessel (2) and for convey blood plasma go out
Blood vessel (6).
2. a kind of whole blood blood plasma automatic separating apparatus according to claim 1, it is characterised in that the rotating disk (1) is in circle
Shape, in the centre bore of rotating disk (1) being provided centrally with for being connected with the rotating mechanism of driving rotating disk (1) rotation.
3. a kind of whole blood blood plasma automatic separating apparatus according to claim 1, it is characterised in that described into the another of blood vessel (2)
One end is connected with whole blood chamber (3), and the maximum distance of the whole blood chamber (3) and axis of rotation is less than disengagement chamber (5) and rotary shaft
The minimum range of the heart.
4. a kind of whole blood blood plasma automatic separating apparatus according to claim 1, it is characterised in that the disengagement chamber (5) is divided into
Erythrocyte preservation portion (501) and blood plasma reservoir (502), Erythrocyte preservation portion (501) are located at the outer of blood plasma reservoir (502)
Side, described to be connected into blood vessel (2) with Erythrocyte preservation portion (501), blood vessel (6) out are connected with blood plasma reservoir (502)
It is logical.
5. a kind of whole blood blood plasma automatic separating apparatus according to claim 4, it is characterised in that the Erythrocyte preservation portion
Volumetric ratio with blood plasma reservoir is 2:3.
6. a kind of whole blood blood plasma automatic separating apparatus according to claim 1, it is characterised in that the disengagement chamber (5) is along rotation
Turntable (1) is arranged radially.
7. a kind of whole blood blood plasma automatic separating apparatus according to claim 1, it is characterised in that on blood vessel (6) out
It is provided with bending part (8), the bending part (8) is less than in disengagement chamber (5) and rotation at a distance from the rotation center of rotating disk (1)
The minimum range of the heart.
8. a kind of whole blood blood plasma automatic separating apparatus according to claim 3, it is characterised in that on the whole blood chamber (3)
It is provided with adding hole (4).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201820702517.9U CN208270290U (en) | 2018-05-11 | 2018-05-11 | A kind of whole blood blood plasma automatic separating apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201820702517.9U CN208270290U (en) | 2018-05-11 | 2018-05-11 | A kind of whole blood blood plasma automatic separating apparatus |
Publications (1)
Publication Number | Publication Date |
---|---|
CN208270290U true CN208270290U (en) | 2018-12-21 |
Family
ID=64682686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201820702517.9U Active CN208270290U (en) | 2018-05-11 | 2018-05-11 | A kind of whole blood blood plasma automatic separating apparatus |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN208270290U (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108593382A (en) * | 2018-05-11 | 2018-09-28 | 石家庄禾柏生物技术股份有限公司 | A kind of whole blood blood plasma automatic separating apparatus |
WO2021121149A1 (en) * | 2019-12-19 | 2021-06-24 | 石家庄禾柏生物技术股份有限公司 | Whole blood separation structure |
-
2018
- 2018-05-11 CN CN201820702517.9U patent/CN208270290U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108593382A (en) * | 2018-05-11 | 2018-09-28 | 石家庄禾柏生物技术股份有限公司 | A kind of whole blood blood plasma automatic separating apparatus |
WO2021121149A1 (en) * | 2019-12-19 | 2021-06-24 | 石家庄禾柏生物技术股份有限公司 | Whole blood separation structure |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5290432B2 (en) | Apparatus and analysis system for agglutination inspection | |
JP6200419B2 (en) | Microfluidic disc for use in bead-based immunoassays | |
US9993816B2 (en) | Apparatus and method for separating and analyzing blood | |
JPH10505672A (en) | Disposable cartridge and assay method for assaying biological samples | |
CN208270290U (en) | A kind of whole blood blood plasma automatic separating apparatus | |
PL176963B1 (en) | Fluid separating method and apparatus | |
US5275731A (en) | Apparatus for rapidly separating blood into filtered fractions | |
JPWO2006038682A1 (en) | Solid-liquid separation / measurement structure and solid-liquid separation / measurement method | |
NO137920B (en) | PHOTOMETRIC ANALYZER. | |
EP3233232A1 (en) | Method and system for buoyant separation | |
CN206838098U (en) | A kind of centrifugal immunological magnetic bead sorting micro-fluidic chip and device | |
JPH11148932A (en) | Blood separation device and method | |
CN110777049A (en) | Microfluidic chip, nucleic acid detector and nucleic acid detection method | |
US20040025603A1 (en) | Test tube insert | |
CN208270312U (en) | A kind of test reaction capsule | |
Yuan et al. | A manual and portable centrifuge combined with a paper-based immunoassay for myocardial infarction diagnosis | |
CN109765391B (en) | Multi-index detection centrifugal test strip chip | |
CN108593382A (en) | A kind of whole blood blood plasma automatic separating apparatus | |
CN208399247U (en) | A kind of test reaction capsule with mixing structure | |
CN208270311U (en) | A kind of reaction capsule with variable diameter row's bubble structure | |
JP4055802B2 (en) | Reaction disk for automatic analyzer | |
CN107643415A (en) | Chemiluminescence immunoassay disc and its method of work based on centrifugal microfluidic control technology | |
CN108444802A (en) | A kind of test reaction capsule | |
US3211530A (en) | Centrifugal separator and analyzing means | |
CN110180611A (en) | Micro-fluidic chip component |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GR01 | Patent grant | ||
GR01 | Patent grant |