CN109602875A - A kind of Chinese medicine composition that treating fever in children, preparation method and applications - Google Patents
A kind of Chinese medicine composition that treating fever in children, preparation method and applications Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine compositions for treating fever in children, it is made of the bulk pharmaceutical chemicals of following weight percentage: windproof 5.00-6.38%, wrinkled giant hyssop 5.00-6.38%, stir-baked FRUCTUS GARDENIAE 2.86-6.67%, gypsum 25.00-28.57%, Radix Glycyrrhizae 2.86-4.48%, radix pseudostellariae 17.91-22.86%, Cortex Magnoliae Officinalis 8.51-10.00%, perilla leaf 10.64-15.00%, stir-baked SEMEN RAPHANI 4.48-6.38%, in one's early teens 4.48-6.38%.The application treat fever in children prescription be plus radix pseudostellariae, Cortex Magnoliae Officinalis, perilla leaf, in one's early teens and stir-baked SEMEN RAPHANI on the basis of rushing down yellow scattered prescription, can be while bringing down a fever, strengthening the spleen and stomach, effect of bringing down a fever is more preferable, and does not allow easy to recur.
Description
Technical field
The invention belongs to technical field of pharmaceuticals, and in particular to a kind of Chinese medicine composition for treating fever in children, preparation method
And its application.
Background technique
Fever is one of most common symptom of Pediatrics disease, and children are most common with fever caused by exogenous disease.Children's hair
Heat can lead to the complication such as faint from fear, be dehydrated, and seriously endanger the life security of infant.The upper breathing of Pediatric Clinic amount 70-80%
It is using fever, cough, pharyngalgia as main clinical manifestation that road, which infects infant, and fever in children is the main reason for coming hospital emergency.
Caused by modern medicine thinks the infection of the upper respiratory tract mostly because of virus and bacterium infection, wherein virus infection accounts for 80-
90%, bacterium infection accounts for 10%.Currently, bacterium heat pyrexia has been achieved with more satisfied curative effect, but in viral heat pyrexia
In terms of Clinical Processing, curative effect is not significant enough.There are analgin, paracetamol etc. with more antipyretic at present, there is short
The problem of body temperature rises again after time brings down a fever, and the adverse drug reaction that above-mentioned Western medicine is all unfavorable there is some pairs of bodies.
Therefore, a collection of Chinese materia medica preparation such as antitoxic bolus of honeysuckle flower and forsythia, Radix Isatidis granules, Herba Sidae Rhombifoliae granule, oral liquid of honeysuckle flower and scutellaria is asked in succession
Generation is widely used in clinical treatment fever in children, achieves certain curative effect, but above-mentioned Chinese medicine is mostly more bitter,
It is difficult to swallow.And said medicine is not directed to the dosage ratio of patient's progress science of specific age bracket, uniquely relies on control clothes
Amount distinguishes the children of all ages and classes, and parents of hospitalized children is difficult to accurately hold, reasonable utilization, and therapeutic effect is not achieved or causes
Some side effects.
Summary of the invention
The purpose of the present invention is overcoming Chinese medicine bitter taste of the existing technology, pediatric patient is difficult to swallow, and does not have
Have and carry out scientific matching for the deficiency of the children of different age group, a kind of Chinese traditional medicine composition that can effectively treat fever in children is provided
Object carries out scientific matching to medicine material, treats more targeted for the children of different age group.
The present invention provides a kind of Chinese medicine compositions for treating fever in children, by the bulk pharmaceutical chemicals system of following weight percentage
At: windproof 5.00-6.38%, wrinkled giant hyssop 5.00-6.38%, stir-baked FRUCTUS GARDENIAE 2.86-6.67%, gypsum 25.00-28.57%, Radix Glycyrrhizae
2.86-4.48%, radix pseudostellariae 17.91-22.86%, Cortex Magnoliae Officinalis 8.51-10.00%, perilla leaf 10.64-15.00%, stir-baked SEMEN RAPHANI
4.48-6.38%, in one's early teens 4.48-6.38%.
Preferably, the Chinese medicine composition of the treatment fever in children is made of the bulk pharmaceutical chemicals of following weight percentage: anti-
Wind 5.71%, wrinkled giant hyssop 5.71%, stir-baked FRUCTUS GARDENIAE 2.86%, gypsum 28.57%, Radix Glycyrrhizae 2.86%, radix pseudostellariae 22.86%, Cortex Magnoliae Officinalis
8.57%, perilla leaf 11.44%, stir-baked SEMEN RAPHANI 5.71%, in one's early teens 5.71%.
Preferably, the Chinese medicine composition of the treatment fever in children is made of the bulk pharmaceutical chemicals of following weight percentage: anti-
Wind 6.38%, wrinkled giant hyssop 6.38%, stir-baked FRUCTUS GARDENIAE 4.26%, gypsum 25.53%, Radix Glycyrrhizae 4.26%, radix pseudostellariae 21.28%, Cortex Magnoliae Officinalis
8.51%, perilla leaf 10.64%, stir-baked SEMEN RAPHANI 6.38%, in one's early teens 6.38%.
Preferably, the Chinese medicine composition of the treatment fever in children is made of the bulk pharmaceutical chemicals of following weight percentage: anti-
Wind 5.66%, wrinkled giant hyssop 5.66%, stir-baked FRUCTUS GARDENIAE 5.66%, gypsum 28.30%, Radix Glycyrrhizae 3.77%, radix pseudostellariae 18.87%, Cortex Magnoliae Officinalis
9.44%, perilla leaf 11.32%, stir-baked SEMEN RAPHANI 5.66%, in one's early teens 5.66%.
Preferably, the Chinese medicine of the treatment fever in children is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
5.45%, wrinkled giant hyssop 5.45%, stir-baked FRUCTUS GARDENIAE 5.46%, gypsum 27.27%, Radix Glycyrrhizae 3.64%, radix pseudostellariae 18.18%, Cortex Magnoliae Officinalis
9.09%, perilla leaf 14.55%, stir-baked SEMEN RAPHANI 5.45%, in one's early teens 5.46%.
Preferably, the Chinese medicine composition of the treatment fever in children is made of the bulk pharmaceutical chemicals of following weight percentage: anti-
Wind 5.00%, wrinkled giant hyssop 5.00%, stir-baked FRUCTUS GARDENIAE 6.67%, gypsum 25.00%, Radix Glycyrrhizae 3.33%, radix pseudostellariae 20.00%, Cortex Magnoliae Officinalis
10.00%, perilla leaf 15.00%, stir-baked SEMEN RAPHANI 5.00%, in one's early teens 5.00%.
Preferably, the Chinese medicine composition of the treatment fever in children is made of the bulk pharmaceutical chemicals of following weight percentage: anti-
Wind 5.97%, wrinkled giant hyssop 5.97%, stir-baked FRUCTUS GARDENIAE 5.97%, gypsum 26.87%, Radix Glycyrrhizae 4.48%, radix pseudostellariae 17.91%, Cortex Magnoliae Officinalis
8.95%, perilla leaf 14.92%, stir-baked SEMEN RAPHANI 4.48%, in one's early teens 4.48%.
The present invention also provides a kind of preparation methods of Chinese medicine composition for treating fever in children, comprising the following steps: (1)
Gypsum 25.00-28.57% is taken, is placed in casserole or stainless-steel pan or terrine or crock or cooking pot for herbs or purple casserole and adds water
It impregnates, boils by intense fire, be decocted first -120 minutes 5 minutes；(2) in the side of taking other Chinese medicine materials by windproof 5.00-6.38%, wrinkled giant hyssop
5.00-6.38%, stir-baked FRUCTUS GARDENIAE 2.86-6.67%, Radix Glycyrrhizae 2.86-4.48%, radix pseudostellariae 17.91-22.86%, Cortex Magnoliae Officinalis 8.51-
10.00%, perilla leaf 10.64-15.00%, stir-baked SEMEN RAPHANI 4.48-6.38%, the proportion mixing of 4.48-6.38% is equal in one's early teens
It is even, it places in the casserole or stainless-steel pan or terrine or crock or cooking pot for herbs or purple casserole of having decocted gypsum, adds water, make water in
The volume mass ratio of medicine raw material is 6-9ml:1g, first boils, is then cooked by slow fire with high heat, and filtering out filtrate is to treat children's hair
The Chinese medicine composition of heat.
The present invention also provides application of the Chinese medicine composition for the treatment of fever in children in terms for the treatment of fever in children.
Although applying on treatment fever in children in the application in one's early teens, it is used in children's exogenous fever
On bathing formula, there is no on the Chinese medicine for the treatment of fever in children directly for oral administration.Because of the routine of those skilled in the art
Cognition is that children are in the process of continuous growth and development, either body, physiology, in terms of, all with it is adult not
Together, the age is smaller more significant；If medicinal preparation for oral administration directly therefore is made in Chinese medicine material, side effect may be generated to patient, especially
It is for young patient, it is difficult to hold dosage, there are security risks.It therefore, is at present usually by Chinese medicine material system
At topical agents such as patch or showering agents, pass through the osmotic absorption of skin surface slowly.And in the application in one's early teens with rush down
Drug, radix pseudostellariae, Cortex Magnoliae Officinalis, perilla leaf and stir-baked SEMEN RAPHANI in the scattered prescription of Huang cooperate jointly, and are directed to the children of different age group,
Corresponding material content is adjusted, different formulas is obtained, the fever of 0-18 years old children can be treated.And it is directed to different age group
Children, be not that all raw material dosages are all tuned up or turned down, but to therein when being adjusted to raw material dosage
The raw material that the dosage of a certain or several raw materials is adjusted, and adjusts every time be all it is different, illustrate the application
Chinese medicine preparation for treatment different age group fever in children patient when, be not arbitrarily carry out raw material dosage plus
Subtract, but on the basis of certain theoretical, by the amount for practicing the object and plus-minus that obtain raw material plus-minus.The application's is a series of
The Chinese medicine for treating fever in children can be according to the age different targetedly selection Chinese medicine preparations of fever in children patient, treatment effect
Fruit is more significant, and side effect is lower.
The application additionally uses stir-baked SEMEN RAPHANI, although radish seed has on treatment fever in children, there is no right
It carries out frying.Shandong Traditional Chinese Medicine University Jia Jingjing is disclosed in " constituent analysis of radish seed medicine materical crude slice and cooked theory research (II) "
Radish seed and stir-baked SEMEN RAPHANI are different due to processing gimmick, and the content of some of them ingredient even type can change, most
Whole effect is also different.The current effect of stir-baked SEMEN RAPHANI is to cure mainly help digestion and eliminate flatulence, lowering the adverse-rising QI to resolve phlegm；For retention of food and drink,
Abdominal distention, constipation, stagnation and diarrhea, phlegm choking, dyspnea and cough；There is no disclose its effect in terms of heat dissipation, therefore, this field
Technical staff does not have motivation that radish seed is used to treat after frying fever in children, and operation can be more complicated.
It is on the basis of rushing down yellow scattered prescription plus radix pseudostellariae, Cortex Magnoliae Officinalis, perilla leaf, grass that the application, which treats the prescription of fever in children,
Cardamom and stir-baked SEMEN RAPHANI.Rushing down yellow dissipate is a kind of Chinese medicinal formulae, cures mainly taste volt fire syndrome, the mesh open sore part is smelly, and polydipsia is easily hungry, the dry lip of mouth
Dry, the red rapid pulse of tongue and the spleen-heat syndrome do tongue etc..Although have at present will rush down one of yellow scattered prescription or plurality of raw materials be used to treat it is small
Youngster's fever, but there is no rushing down yellow scattered prescription by entire and being used to treat fever in children, rush down it is yellow dissipate be taste fire, exogenous disease hair
The usual injuring spleen-stomach of heat, if simple is antipyretic, calorific potential is difficult to retreat, more the impairment of the spleen, this is also that current antipyretic is easy back
The reason of heat；Therefore, treatment fever in children should take taste into account, and alexipyretic is never crossed with bitter cold and impairment of yang is upset one's stomach, and the application exists
It rushes down and radix pseudostellariae, Cortex Magnoliae Officinalis, perilla leaf, in one's early teens and stir-baked SEMEN RAPHANI is added on the basis of yellow scattered prescription, it can be while bringing down a fever, invigorating the spleen
Stomach, effect of bringing down a fever is more preferable, and does not allow easy to recur.
The application adheres to the theory of " being generated heat by heresy, human body inspires healthy tendency and evil confrontation, generates thermal image ", for fever in children
Pathological characters allow whole body mechanism of qi to circulate using the method for invigorating the spleen treatment for relieving indigestion and constipation.Curative effect is obvious, really embodies " searching for the primary cause of disease in treatment ".This
The prescription pungent-warm medicine of a cold nature of application is used in combination, and children Yi Han is easily warm, and trembling with fear from thermalization or heat is cold beam, and simple chill wind-heat is more rare, controls
In treatment, single pungent-warm, often fever subsiding after perspiration, but it is easy to recur；Single pungent cool, often sweating is impermeable, and table heresy is not easy to release.And pungent-warm
It is pungent it is cool be used in combination, self energy chill wind-heat two solves, and heat moves back without recovering.
The beneficial effects of the present invention are:
1, in one's early teens common with the drug, radix pseudostellariae, Cortex Magnoliae Officinalis, perilla leaf and the stir-baked SEMEN RAPHANI that rush down in yellow scattered prescription in the application
Cooperation, and the children of different age group are directed to, corresponding material content is adjusted, different formulas is obtained, 0-18 can be treated
Year children fever, can be used for treating acute upper respiratory infection, common cold of gastrointestinal type, acute bronchitis, various infectious diseases etc.
Caused fever, it is efficient up to 98% or more.
2, medicine material of the invention progress scientific matching adjusts corresponding raw material and contains for the children of different age group
Amount, obtains different formulas, can treat the fever of 0-18 years old children.
3, the application treat the prescription of fever in children be on the basis of rushing down yellow scattered prescription plus radix pseudostellariae, Cortex Magnoliae Officinalis, perilla leaf,
In one's early teens and stir-baked SEMEN RAPHANI, can be while bringing down a fever, strengthening the spleen and stomach, effect of bringing down a fever is more preferable, and does not allow easy to recur.
4, the present invention is extracted using natural Chinese medicinal herb, and without using synthesis industrial chemicals, production cost is low, and safety can
It is used for a long time, it is small to human body toxic side effect.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with specific embodiment, to this hair
Bright further description.
Embodiment 1
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
5.71%, wrinkled giant hyssop 5.71%, stir-baked FRUCTUS GARDENIAE 2.86%, gypsum 28.57%, Radix Glycyrrhizae 2.86%, radix pseudostellariae 22.86%, Cortex Magnoliae Officinalis
8.57%, perilla leaf 11.44%, stir-baked SEMEN RAPHANI 5.71%, in one's early teens 5.71%.
Preparation method are as follows:
(1) gypsum 10g is taken, is placed in casserole or stainless-steel pan or terrine or crock or cooking pot for herbs or purple casserole and adds water
200ml impregnates, and boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 2g, wrinkled giant hyssop 2g, stir-baked FRUCTUS GARDENIAE 1g, Radix Glycyrrhizae 1g, crown prince
Join 8g, Cortex Magnoliae Officinalis 3g, perilla leaf 4g, stir-baked SEMEN RAPHANI 2g, 2g is uniformly mixed in one's early teens, is placed on the casserole or stainless steel for having decocted gypsum
In pot or terrine or crock or cooking pot for herbs or purple casserole, 200ml is added water to, impregnates 20 minutes, is first boiled by intense fire on fire, then
It is cooked by slow fire again 10-15 minutes, filters out medical fluid 60ml, be taken in two divided doses daily.This Chinese medicine is suitable for 0-1 years old child patient.
Embodiment 2
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
6.38%, wrinkled giant hyssop 6.38%, stir-baked FRUCTUS GARDENIAE 4.26%, gypsum 25.53%, Radix Glycyrrhizae 4.26%, radix pseudostellariae 21.28%, Cortex Magnoliae Officinalis
8.51%, perilla leaf 10.64%, stir-baked SEMEN RAPHANI 6.38%, in one's early teens 6.38%.
Preparation method are as follows: (1) take gypsum 12g, be placed on casserole or stainless-steel pan or terrine or crock or cooking pot for herbs
Or add water 300ml to impregnate in purple casserole, it boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 3g, wrinkled giant hyssop 3g, stir-baked FRUCTUS GARDENIAE
2g, Radix Glycyrrhizae 2g, radix pseudostellariae 10g, Cortex Magnoliae Officinalis 4g, perilla leaf 5g, stir-baked SEMEN RAPHANI 3g, 3g is uniformly mixed in one's early teens, is placed on and has been decocted raw stone
In the casserole or stainless-steel pan or terrine or crock or cooking pot for herbs or purple casserole of cream, 300ml is added water to, is impregnated 20 minutes, in fire
It is upper first to boil by intense fire, it is then cooked by slow fire again 10-15 minutes, filters out medical fluid 120ml, be taken in two divided doses daily.This Chinese medicine is applicable in
In 1-3 years old child patient.
Embodiment 3
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
5.66%, wrinkled giant hyssop 5.66%, stir-baked FRUCTUS GARDENIAE 5.66%, gypsum 28.30%, Radix Glycyrrhizae 3.77%, radix pseudostellariae 18.87%, Cortex Magnoliae Officinalis
9.44%, perilla leaf 11.32%, stir-baked SEMEN RAPHANI 5.66%, in one's early teens 5.66%.
Preparation method are as follows: (1) take gypsum 15g, be placed on casserole or stainless-steel pan or terrine or crock or cooking pot for herbs
Or add water 300ml to impregnate in purple casserole, it boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 3g, wrinkled giant hyssop 3g, stir-baked FRUCTUS GARDENIAE
3g, Radix Glycyrrhizae 2g, radix pseudostellariae 10g, Cortex Magnoliae Officinalis 5g, perilla leaf 6g, stir-baked SEMEN RAPHANI 3g, 3g is uniformly mixed in one's early teens, is placed on and has been decocted raw stone
In the casserole or stainless-steel pan or terrine or crock or cooking pot for herbs or purple casserole of cream, 300ml is added water to, is impregnated 20 minutes, in fire
It is upper first to boil by intense fire, it is then cooked by slow fire again 10-15 minutes, filters out medical fluid 150ml, be taken in two divided doses daily.This Chinese medicine is applicable in
In 3-6 years old child patient.
Embodiment 4
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
5.45%, wrinkled giant hyssop 5.45%, stir-baked FRUCTUS GARDENIAE 5.46%, gypsum 27.27%, Radix Glycyrrhizae 3.64%, radix pseudostellariae 18.18%, Cortex Magnoliae Officinalis
9.09%, perilla leaf 14.55%, stir-baked SEMEN RAPHANI 5.45%, in one's early teens 5.46%.
Preparation method are as follows: (1) take gypsum 15g, be placed on casserole or or stainless-steel pan or terrine or crock or boil medicine
In pot or purple casserole plus water 400ml impregnates, and boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 3g, wrinkled giant hyssop 3g, Cape jasmine is fried
Sub- 3g, Radix Glycyrrhizae 2g, radix pseudostellariae 10g, Cortex Magnoliae Officinalis 5g, perilla leaf 8g, stir-baked SEMEN RAPHANI 3g, in one's early teens 3g be uniformly mixed, be placed on casserole or
400ml is added water in stainless-steel pan or terrine or crock or cooking pot for herbs or purple casserole, is impregnated 20 minutes, and first intense fire boils on fire
Boiling, is then cooked by slow fire 10-15 minutes again, filters out medical fluid 200ml, be taken in two divided doses daily.This Chinese medicine was suitable for 6-10 years old
Child patient.
Embodiment 5
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
5.00%, wrinkled giant hyssop 5.00%, stir-baked FRUCTUS GARDENIAE 6.67%, gypsum 25.00%, Radix Glycyrrhizae 3.33%, radix pseudostellariae 20.00%, Cortex Magnoliae Officinalis
10.00%, perilla leaf 15.00%, stir-baked SEMEN RAPHANI 5.00%, in one's early teens 5.00%.
Preparation method are as follows: (1) take gypsum 15g, be placed on casserole or stainless-steel pan or terrine or crock or cooking pot for herbs
Or add water 500ml to impregnate in purple casserole, it boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 3g, wrinkled giant hyssop 3g, stir-baked FRUCTUS GARDENIAE
4g, Radix Glycyrrhizae 2g, radix pseudostellariae 12g, Cortex Magnoliae Officinalis 6g, perilla leaf 9g, stir-baked SEMEN RAPHANI 3g, 3g is uniformly mixed in one's early teens, is placed on casserole or not
It becomes rusty in steel pot or terrine or crock or cooking pot for herbs or purple casserole, adds water to 500ml and impregnate 20 minutes, first boiled by intense fire on fire,
Then it is cooked by slow fire again 10-15 minutes, filters out medical fluid 250ml, be taken in two divided doses daily.This Chinese medicine is suitable for 10-14 years old youngster
Virgin patient.
Embodiment 6
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
5.97%, wrinkled giant hyssop 5.97%, stir-baked FRUCTUS GARDENIAE 5.97%, gypsum 26.87%, Radix Glycyrrhizae 4.48%, radix pseudostellariae 17.91%, Cortex Magnoliae Officinalis
8.95%, perilla leaf 14.92%, stir-baked SEMEN RAPHANI 4.48%, in one's early teens 4.48%.
Preparation method are as follows: (1) take gypsum 18g, be placed on casserole or stainless-steel pan or terrine or crock or cooking pot for herbs
Or add water 500ml to impregnate in purple casserole, it boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 4g, wrinkled giant hyssop 4g, stir-baked FRUCTUS GARDENIAE
4g, Radix Glycyrrhizae 3g, radix pseudostellariae 12g, Cortex Magnoliae Officinalis 6g, perilla leaf 10g, stir-baked SEMEN RAPHANI 3g, 3g is uniformly mixed in one's early teens, is placed on casserole or not
It becomes rusty in steel pot or terrine or crock or cooking pot for herbs or purple casserole, adds water to 500ml, impregnate 20 minutes, first boiled by intense fire on fire,
Then it is cooked by slow fire again 10-15 minutes, filters out medical fluid 250ml, be taken in two divided doses daily.This Chinese medicine is suitable for 14-18 years old youngster
Virgin patient.
Comparative example 1
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
6.38%, wrinkled giant hyssop 6.38%, stir-baked FRUCTUS GARDENIAE 4.26%, gypsum 28.72%, Radix Glycyrrhizae 4.26%, radix pseudostellariae 24.47%, Cortex Magnoliae Officinalis
8.51%, perilla leaf 10.64%, stir-baked SEMEN RAPHANI 6.38%.
Preparation method are as follows: (1) take gypsum 13.5g, be placed on casserole or stainless-steel pan or terrine or crock or boil medicine
In pot or purple casserole plus water 300ml impregnates, and boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 3g, wrinkled giant hyssop 3g, Cape jasmine is fried
Sub- 2g, Radix Glycyrrhizae 2g, radix pseudostellariae 11.5g, Cortex Magnoliae Officinalis 4g, perilla leaf 5g, stir-baked SEMEN RAPHANI 3g are uniformly mixed, and are placed on casserole or stainless-steel pan
Or in terrine or crock or cooking pot for herbs or purple casserole, 300ml is added water to, impregnates 20 minutes, is first boiled by intense fire on fire, then again
It is cooked by slow fire 10-15 minutes, filters out medical fluid 120ml, be taken in two divided doses daily.This Chinese medicine is suitable for 1-3 years old child patient.
Comparative example 2
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
6.38%, wrinkled giant hyssop 6.38%, stir-baked FRUCTUS GARDENIAE 4.26%, gypsum 25.53%, Radix Glycyrrhizae 4.26%, radix pseudostellariae 21.28%, Cortex Magnoliae Officinalis
8.51%, perilla leaf 10.64%, radish seed 6.38%, in one's early teens 6.38%.
Preparation method are as follows: (1) take gypsum 12g, be placed on casserole or stainless-steel pan or terrine or crock or cooking pot for herbs
Or add water 300ml to impregnate in purple casserole, it boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 3g, wrinkled giant hyssop 3g, stir-baked FRUCTUS GARDENIAE
2g, Radix Glycyrrhizae 2g, radix pseudostellariae 10g, Cortex Magnoliae Officinalis 4g, perilla leaf 5g, radish seed 3g, 3g is uniformly mixed in one's early teens, is placed on casserole or stainless
In steel pot or terrine or crock or cooking pot for herbs or purple casserole, 300ml is added water to, impregnates 20 minutes, is first boiled by intense fire on fire, so
It is cooked by slow fire again afterwards 10-15 minutes, filters out medical fluid 120ml, be taken in two divided doses daily.This Chinese medicine was suffered from suitable for 1-3 years old children
Person.
Comparative example 3
A kind of Chinese medicine composition for treating fever in children, is made of the bulk pharmaceutical chemicals of following weight percentage: radix saposhnikoviae
6.38%, wrinkled giant hyssop 6.38%, stir-baked FRUCTUS GARDENIAE 4.26%, gypsum 28.72%, Radix Glycyrrhizae 4.26%, radix pseudostellariae 24.47%, Cortex Magnoliae Officinalis
8.51%, perilla leaf 10.64%, radish seed 6.38%.
Preparation method are as follows: (1) take gypsum 13.5g, be placed on casserole or stainless-steel pan or terrine or crock or boil medicine
In pot or purple casserole plus water 300ml impregnates, and boils by intense fire, is decocted first -120 minutes 5 minutes；(2) by windproof 3g, wrinkled giant hyssop 3g, Cape jasmine is fried
Sub- 2g, Radix Glycyrrhizae 2g, radix pseudostellariae 11.5g, Cortex Magnoliae Officinalis 4g, perilla leaf 5g, radish seed 3g be uniformly mixed, be placed on casserole or stainless-steel pan or
In terrine or crock or cooking pot for herbs or purple casserole, 300ml is added water to, impregnates 20 minutes, is first boiled by intense fire on fire, it is then literary again
Fire decocts 10-15 minutes, filters out medical fluid 120ml, is taken in two divided doses daily.This Chinese medicine is suitable for 1-3 years old child patient.
Clinical use effect experiment:
Choose fever in children patient totally 300, body temperature at 38-40 DEG C, the age at 1-3 year old, be randomly divided into 5 treatment groups with
1 control group, every group 50.Every group of gender, course of disease etc. are statistically analyzed, and no significant difference (P > 0.05) has
Comparativity.
Diagnostic criteria: all fever in children meet Chinese medicine cold in children diagnostic criteria, and clinical manifestation is fever, nasal obstruction, runny nose
Or with cold symptoms such as cough, Nausea and vomitings.
Therapeutic component is 5 groups of 1 group for the treatment of, 2 groups for the treatment of, 3 groups for the treatment of, 4 groups for the treatment of and treatment, is given respectively by of the invention real
Apply example 2 and 4, the Chinese medicine of comparative example 1,2 and 3 resulting treatment fever in children, wherein the patient treated in 2 groups gives embodiment 4
The taking dose of the Chinese medicine of obtained treatment fever in children reduces 0.2 times, i.e., the dosage of all drugs reduces 0.2 times.Control
The patient of group takes children-welfare tablet (dispelling pathogenic wind and eliminating phlegm, clearing heat and detoxicating, for cold, fever, convulsive seizure due to phlegm-fire is interior to be contained, the diseases such as fever and headache) mouth
Clothes, one at a time, 3 times a day.2 weeks are 1 course for the treatment of, and 2 courses for the treatment of are used in conjunction in treatment group and control group.
Criterion of therapeutical effect: referring to Ministry of Health of the People's Republic of China's pharmaceutical control and administration department, " it is (anxious that new drug (Chinese medicine) treats children's exogenous fever
The property infection of the upper respiratory tract) guideline of clinical investigations " it drafts.To bring down a fever for main indicator.It cures: in medication 24-48h, body temperature
Restore normal level, and do not go up again, symptom disappears；It is effective: in medication 24-48h, temperature recovery normal level, mainly
Symptom largely disappears；It is effective: in medication 24-48h, temperature recovery normal level, cardinal symptom partial disappearance；It is invalid: not to be inconsistent
Close the above standard.
The wherein efficient percentage that every group of total number of persons is accounted for for recovery from illness, effective and effective number.
Patient's treatment condition of each treatment group and control group is counted, and calculates its effective percentage, the results are shown in Table 1.
The treated effect of table 1 treatment group and control group
From the point of view of above-mentioned experimental result, the Chinese medicine for treating fever in children obtained using the raw material proportioning in embodiment 2,
Therapeutic effect is better than control group, that is, treats 1 group of effective percentage and be higher than control group, illustrates to match according to the Chinese medicine of the present embodiment 2
Its effect for treating 1-3 years old fever in children of the Chinese medicine just obtained is better than common drug currently on the market, and side effect is low,
Recurrence rate is low.
In addition 1 group is treated compared with 2 groups for the treatment of, and treated effect is higher, if illustrating the not patient according to different age group
The amount of the targetedly object of selection formula material plus-minus and plus-minus is carried out, and only controls and takes when taking Chinese medicine
Amount distinguish the children of all ages and classes, final therapeutic effect is poor.
3,4 and 5 groups are treated compared with 1 group for the treatment of, treated effect is lower, illustrates to lack in one's early teens and/or not by radish
The Chinese medicine for the treatment fever in children that son is obtained by frying, therapeutic effect are not so good as Chinese medicine obtained in the embodiment of the present application 2
Therapeutic effect.
Claims (9)
1. a kind of Chinese medicine composition for treating fever in children, which is characterized in that be made of the bulk pharmaceutical chemicals of following weight percentage:
Windproof 5.00-6.38%, wrinkled giant hyssop 5.00-6.38%, stir-baked FRUCTUS GARDENIAE 2.86-6.67%, gypsum 25.00-28.57%, Radix Glycyrrhizae
2.86-4.48%, radix pseudostellariae 17.91-22.86%, Cortex Magnoliae Officinalis 8.51-10.00%, perilla leaf 10.64-15.00%, stir-baked SEMEN RAPHANI
4.48-6.38%, in one's early teens 4.48-6.38%.
2. the Chinese medicine composition for the treatment of fever in children as described in claim 1, which is characterized in that by following weight percentage
Bulk pharmaceutical chemicals are made: radix saposhnikoviae 5.71%, wrinkled giant hyssop 5.71%, stir-baked FRUCTUS GARDENIAE 2.86%, gypsum 28.57%, Radix Glycyrrhizae 2.86%, radix pseudostellariae
22.86%, Cortex Magnoliae Officinalis 8.57%, perilla leaf 11.44%, stir-baked SEMEN RAPHANI 5.71%, in one's early teens 5.71%.
3. the Chinese medicine composition for the treatment of fever in children as described in claim 1, which is characterized in that by following weight percentage
Bulk pharmaceutical chemicals are made: radix saposhnikoviae 6.38%, wrinkled giant hyssop 6.38%, stir-baked FRUCTUS GARDENIAE 4.26%, gypsum 25.53%, Radix Glycyrrhizae 4.26%, radix pseudostellariae
21.28%, Cortex Magnoliae Officinalis 8.51%, perilla leaf 10.64%, stir-baked SEMEN RAPHANI 6.38%, in one's early teens 6.38%.
4. the Chinese medicine composition for the treatment of fever in children as described in claim 1, which is characterized in that by following weight percentage
Bulk pharmaceutical chemicals are made: radix saposhnikoviae 5.66%, wrinkled giant hyssop 5.66%, stir-baked FRUCTUS GARDENIAE 5.66%, gypsum 28.30%, Radix Glycyrrhizae 3.77%, radix pseudostellariae
18.87%, Cortex Magnoliae Officinalis 9.44%, perilla leaf 11.32%, stir-baked SEMEN RAPHANI 5.66%, in one's early teens 5.66%.
5. the Chinese medicine composition for the treatment of fever in children as described in claim 1, which is characterized in that by following weight percentage
Bulk pharmaceutical chemicals are made: radix saposhnikoviae 5.45%, wrinkled giant hyssop 5.45%, stir-baked FRUCTUS GARDENIAE 5.46%, gypsum 27.27%, Radix Glycyrrhizae 3.64%, radix pseudostellariae
18.18%, Cortex Magnoliae Officinalis 9.09%, perilla leaf 14.55%, stir-baked SEMEN RAPHANI 5.45%, in one's early teens 5.46%.
6. the Chinese medicine composition for the treatment of fever in children as described in claim 1, which is characterized in that by following weight percentage
Bulk pharmaceutical chemicals are made: radix saposhnikoviae 5.00%, wrinkled giant hyssop 5.00%, stir-baked FRUCTUS GARDENIAE 6.67%, gypsum 25.00%, Radix Glycyrrhizae 3.33%, radix pseudostellariae
20.00%, Cortex Magnoliae Officinalis 10.00%, perilla leaf 15.00%, stir-baked SEMEN RAPHANI 5.00%, in one's early teens 5.00%.
7. the Chinese medicine composition for the treatment of fever in children as described in claim 1, which is characterized in that by following weight percentage
Bulk pharmaceutical chemicals are made: radix saposhnikoviae 5.97%, wrinkled giant hyssop 5.97%, stir-baked FRUCTUS GARDENIAE 5.97%, gypsum 26.87%, Radix Glycyrrhizae 4.48%, radix pseudostellariae
17.91%, Cortex Magnoliae Officinalis 8.95%, perilla leaf 14.92%, stir-baked SEMEN RAPHANI 4.48%, in one's early teens 4.48%.
8. treating the preparation method of the Chinese medicine composition of fever in children as described in claim any one of 1-6, which is characterized in that packet
It includes following steps: (1) taking gypsum 25.00-28.57% according to raw material percentage composition described in any one of claims 1-6, put
It sets and is soaked in water in casserole or stainless-steel pan or terrine or crock or cooking pot for herbs or purple casserole, boiled by intense fire, the 0.5-1 that is decocted first is small
When；(2) windproof 5.00-6.38%, wrinkled giant hyssop 5.00-6.38%, stir-baked FRUCTUS GARDENIAE 2.86-6.67%, Radix Glycyrrhizae 2.86-4.48% are taken, too
Son joins 17.91-22.86%, Cortex Magnoliae Officinalis 8.51-10.00%, perilla leaf 10.64-15.00%, stir-baked SEMEN RAPHANI 4.48-6.38%, careless beans
The proportion of cool 4.48-6.38% is uniformly mixed, and is placed the casserole for having decocted gypsum or stainless-steel pan or terrine or crock or is boiled medicine
In pot or purple casserole, add water, makes the volume mass of water and Chinese medicine material ratio 6-9ml:1g, first boil with high heat, then mild fire
It decocts, filtering out filtrate is the Chinese medicine composition for treating fever in children.
9. treating Chinese medicine composition the answering in terms for the treatment of fever in children of fever in children as described in claim any one of 1-6
With.
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Non-Patent Citations (3)
| Title |
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| 刘敏: "《钱乙传世名方》", 28 February 2013, 中国医药科技出版社 * |
| 周海平: "《常用方剂药理与临床应用》", 31 January 2005, 内蒙古科学出版社 * |
| 王进进等: "小儿发热治验撷要", 《中华中医药杂志》 * |
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