CN109602853A - It is a kind of to treat myopia and presbyopic Traditional Chinese medicine eye drop and preparation method thereof - Google Patents

It is a kind of to treat myopia and presbyopic Traditional Chinese medicine eye drop and preparation method thereof Download PDF

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CN109602853A
CN109602853A CN201910059543.3A CN201910059543A CN109602853A CN 109602853 A CN109602853 A CN 109602853A CN 201910059543 A CN201910059543 A CN 201910059543A CN 109602853 A CN109602853 A CN 109602853A
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chinese medicine
presbyopic
traditional chinese
myopia
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张书翔
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Guizhou Dong Jiazhai Pharmaceutical Technology Co Ltd
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Guizhou Dong Jiazhai Pharmaceutical Technology Co Ltd
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Abstract

Myopia and presbyopic Traditional Chinese medicine eye drop and preparation method thereof are treated the invention discloses a kind of, belongs to technical field of traditional Chinese medicine preparation.Treatment myopia and presbyopic Traditional Chinese medicine eye drop, are made of the raw material of following parts by weight: 20-45 parts of cassia seed, 40-70 parts of honeysuckle, 50-90 parts of pipewort, 30-50 parts of roxburgh anoectochilus terminal bud, 15-40 parts of wolfberry leaf, 30-50 parts of butterflybush flower, 20-30 parts of the coptis, 35-55 parts of Herba Cistanches, 25-45 parts of cynomorium songaricum, mulberries are 20-50 parts sub-, 10-30 parts of red ginseng, 20-45 parts of Semen Cuscutae, 5-10 parts of snake bile, 25-40 parts of cordyceps flower, 20-35 parts of peppermint, 10-20 parts of borax, 10-30 parts of the seed of feather cockscomb and 300-500 parts of honey.Treatment myopia and presbyopic Traditional Chinese medicine eye drop of the invention is mainly used for treating the eye diseases such as myopia, presbyopia, muscae volitantes, the view unclean, tearing against wind of object.

Description

It is a kind of to treat myopia and presbyopic Traditional Chinese medicine eye drop and preparation method thereof
Technical field
Myopia and presbyopic Traditional Chinese medicine eye drop and preparation method thereof are treated the present invention relates to a kind of, belongs to Chinese materia medica preparation skill Art field.
Background technique
Eyes are one of vitals of human body, once eye illness occurs, many pains can be all brought to patient.It is especially close It is very high eye illness of falling ill in recent years depending on, presbyopia etc..
Myopia is normally due to bad caused with eye habit.The etiology and pathology of myopia:, often need to be by mesh such as books and newspapers when myopia is initial Mark shift near or can be seen under strong light, though later object put closely cannot also see it is clean, if reluctantly read or sit closely Work just will appear ophthalmodynia the handwriting is blurred or even the asthenopias symptoms such as headache.It there is no preferable medicine in treatment method at present Object, majority are treated using wearing spectacles, health-care appliance, use operative treatment, current market sales of eye in severe cases Protecting the health care instruments such as instrument, physiotherapeutic glasses for myopia cannot cure although some effects, and the easy to recur and exacerbation state of an illness, also have Drug such as medicine for treating myopia, not only price is high, but also medicine is placed on ocular region massaging, and using trouble, drug effect is not in place, and treatment time is long, hand Art treatment sequelae is more, and laser therapy eyesight is unstable.And surgical laser taboo is more, age requirement is after 18 years old.
Presbyopia is medically also known as presbyopia, is more common in 40 years old or more the middle-aged and the old, phacosclerosis, and elasticity weakens, eyelash Shape flesh contractility, which reduces beautiful cause and adjusts to subtract, to be shown off, and near point far moves, therefore it is difficult that closely view object occurs.This phenomenon is known as presbyopia, Namely myopia, presbyopia, are the performances of human eye adjustment effect aging.Presbyopic etiology and pathology: presbyopia is natural Physiological ageing phenomenon, everyone can generate this phenomenon about from 40 years old, and since crystalline gradually hardens, elasticity gradually lowers, Its flexibility is lost, enough cannot be heaved, therefore produces conciliation deficiency, thus feels difficult when regarding close, usually Presbyopic is that everyone unavoidable Physiological effect weakens process, becomes degree with advancing age and gradually deepens.Treatment at present Presbyopia can only wear presbyopic glasses.
Currently, still lacking treatment myopia, presbyopic eyedrops or similar products.Therefore, social eye disease patient is urgently Have it is a kind of treat myopia, presbyopic drug comes out.
To sum up, it needs to develop a kind of new treatment myopia and presbyopic Traditional Chinese medicine eye drop and preparation method thereof, to make up Drawbacks described above.
Summary of the invention
An object of the present invention, be to provide it is a kind of treat myopia and presbyopic Traditional Chinese medicine eye drop.Treatment of the invention Near-sighted and presbyopic Traditional Chinese medicine eye drop is pure Chinese medicine eye, and without any non-natural chemical component, it is close to be mainly used for treatment Depending on eye diseases such as, presbyopia, muscae volitantes, the view unclean, tearing against wind of object, effect is good, expense is low, short treating period.
The technical scheme to solve the above technical problems is that a kind of treat myopia and presbyopic Chinese medicine medicament for the eyes Water is made of the raw material of following parts by weight: 20-45 parts of cassia seed, 40-70 parts of honeysuckle, 50-90 parts of pipewort, roxburgh anoectochilus terminal bud 30-50 parts, 15-40 parts of wolfberry leaf, 30-50 parts of butterflybush flower, 20-50 parts of the coptis, 35-55 parts of Herba Cistanches, 25-45 parts of cynomorium songaricum, mulberry 20-50 parts of Shen, 10-30 parts of red ginseng, 20-45 parts of Semen Cuscutae, 5-10 parts of snake bile, 25-40 parts of cordyceps flower, 20-35 parts of peppermint, 10-20 parts of borax, 10-30 parts of the seed of feather cockscomb and 300-500 parts of honey.
The introduction of the effect of raw material that the present invention chooses:
Cassia seed, is the dry mature seed of legume cassia or little cassia tora, bitter, sweet, salty, cold nature, return liver, Kidney, large intestine channel have the effect of clearing liver, improving eyesight, Li Shui, defaecation, and it is hard to cure mainly wind-heat cute conjunctivitis, optic atrophy, night blindness, hypertension, hepatitis, liver Change the illnesss such as ascites, habitual constipation.
Honeysuckle, it is cold in nature, sweet in flavor, it attaches to the lung and stomach meridians, there is the effect of clearing heat and detoxicating, dispelling wind and heat from the body, at the beginning of curing mainly carbuncle, swelling and furuncle It rises, red and swollen heat pain, affection of exogenous wind-heat, warm disease are from the beginning of, illnesss such as toxic-heat and blood stasis, hot summer weather polydipsia, abscess of throat.
Pipewort, it is acrid flavour, sweet, it is mild-natured, have the effect of dispelling wind and heat from the body, removing nebula, cure mainly wind-heat hot eyes, swelling and pain photophobia, The illnesss such as raw screen film of mesh, headache due to pathogenic wind-heat.
Roxburgh anoectochilus terminal bud, it is sweet in flavor, it is mild-natured, clearing heat and cooling blood, evacuate pathogenic wind dampness removing, heart tonifying diuresis, reinforce the kidney, calming the liver the effect of.
Wolfberry leaf, it is bitter, sweet, it is cool in nature, return liver,spleen,kidney to pass through, has liver-kidney tonifying, promotes the production of body fluid to quench thirst, dispelling wind and eliminating dampness, promoting blood circulationization The effect of stasis of blood, cures mainly the illnesss such as the confused pain of deficient fever, polydipsia, hot eyes, metrorrhagia and metrostaxis leukorrhagia, heat toxin sore swells.
Butterflybush flower, sweet in flavor, cool in nature, return liver warp have the effect of wind-dispelling, cool blood, profit liver, improving eyesight, cure mainly red eye, swell pain, more tears The illnesss such as photophobia, optic atrophy ocular, the rotten eye of wind string.
The coptis, bitter is cold in nature, and return heart, liver, gallbladder, stomach, large intestine channel have the effect of heat-clearing and damp-drying drug, purging fire for removing toxin.
Herba Cistanches, it is sweet in flavor, salty, it is warm-natured, return kidney, large intestine channel, there is the effect of kidney-replenishing, benefiting essence-blood, ease constipation road.
Cynomorium songaricum, it is sweet in flavor, it is warm-natured.Return liver, kidney, large intestine channel, tonify the kidney and support yang, strengthen muscles and bones, relax bowel and defecation the effect of, cure mainly The illnesss such as the insufficiency of the kidney yang, blood and essence asthenia, waist knee impotence, impotence involuntary emission, dry constipation of intestines.
Mulberries, sweet in flavor, sour, cold in nature, return heart, liver and kidney channel have the effect of nourishing liver and kidney, nourishing yin and nourishing blood.
Red ginseng, sweet in flavor, bitter, warm-natured, return heart, lung, the spleen channel have qi-restoratives, tonifying primordial Qi, replenishing and activating blood and dispelling wind and removing dampness, multiple arteries and veins solid The effect of de-.
Semen Cuscutae, it is sweet in flavor, it is warm-natured, return liver and kidney channel, there is the effect of nourishing liver and kidney, astringent sperm contracting urine, miscarriage prevention, improving eyesight, antidiarrheal, Cure mainly impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, threatened abortion, spleen kidney deficiency are rushed down Illness.
Snake gall is the gall-bladder of storage bile in snake body, and bitter, micro-sweet are cool in nature, has dispelling wind and eliminating dampness, refrigerant improving eyesight, removing toxic substances to go The effect of miliaria.
Cordyceps flower is not spent, substantially cordyceps militaris sporocarp, rather than cordyceps sporophore, is had liver and kidney benefiting, is mended essence Marrow, clears phlegm.
Peppermint, acrid flavour is cool in nature, return lung, Liver Channel, has faint scent to rise scattered, wind-dispelling heat-dissipating, refresh oneself, throat, promoting eruption, relieve stagnation The effect of, cure mainly wind-heat table disease, headache and dizziness, red eye, swell pain, sore throat sound dumb, nasosinusitis, toothache, measles without adequate eruption, urticaria itch, liver The illnesss such as the strongly fragrant swollen, scrofula tuberculosis of hypochondriac pain gastral cavity.
Borax, it is sweet in flavor, salty, it is cool in nature, it attaches to the lung and stomach meridians, there is the effect of heat-clearing and phlegm-dissolving, detoxifying and anticorrosive.
The seed of feather cockscomb, bitter is cool in nature, return liver warp, there is the effect of wind-dispelling heat, clearing away the liver-fire, removing nebula, cure mainly the hot hot eyes of liver, The illnesss such as screen of looking unfamiliar film, blurring of vision, hepatopyretic vertigo.
Honey, sweet in flavor, mild-natured, return lung, spleen, large intestine channel have removing toxic substances, qi-restoratives, moistening lung to arrest cough, moistening dryness for relaxing bowels, bowl spares emergency The effect of.
Prescription solution:
The eye diseases such as the myopia due to caused by many reasons, presbyopia, muscae volitantes, the view unclean, tearing against wind of object.Chinese medicine Think that liver opening at eye, sleeping blood are attributed to liver, mesh can be regarded by blood.Caused by liver and kidney deficiency, liver network, which loses, to be grown, then Liver Channel disorder of meridian-QI, liver and gallbladder It is damp and hot, certainly by disease in eye.Eye illness is treated, palpus kidney-nourishing is secondary to repair edema with the liver involved.Liver is the seedling of kidney, and kidney is liver sheet.Tonifying liver then pacify by the state of mind It is quiet, kidney tonifying then smart soul peace and.Smart soul peace and eyes are naturally bright.Liver kidney deficiency damage, the blood network stasis of blood is stagnant, and it is to lead to eye disease that internal heat is excessively prosperous The main reason for sick.Therefore nourishing liver and kidney, replenishing and activating blood, the method for hot evil removing of dispelling are used in treatment.
Pipewort, honeysuckle have wind-dispelling cool blood, profit liver, dispelling wind and heat from the body, swelling and pain photophobia, removing nebula, clearing heat and detoxicating function Effect, is altogether monarch drug in a prescription.Cassia seed, wolfberry leaf, peppermint, the seed of feather cockscomb have clearing liver, Li Shui, defaecation, promote the production of body fluid to quench thirst, dispelling wind and eliminating dampness, faint scent It rises and dissipates, wind-dispelling heat-dissipating, assists the effect of monarch drug in a prescription liver-kidney tonifying, promoting eruption relieve stagnation, be for ministerial drug.Herba Cistanches, cynomorium songaricum, mulberries are sub, red Ginseng, cordyceps flower, roxburgh anoectochilus terminal bud have qi-restoratives, tonifying primordial Qi, benefiting essence-blood, veins takes off admittedly, nourishing liver and kidney, nourishing yin and nourishing blood, tonify the kidney and support yang, strengthening tendons The effect of bone strengthening is for adjutant.Honey, snake bile, Semen Cuscutae, the coptis, borax have heat-clearing, purging fire for removing toxin, dispelling wind and heat from the body, heat toxin The effect of antidiarrheal, detoxifying and anticorrosive is to make medicine.
The above drug after compatibility acts synergistically, reach jointly tonifying liver, kidney tonifying, grow stomach tonifying spleen, it is promoting blood circulation and removing obstruction in channels, enrich blood it is bright The effect of mesh, the barrier that disappears are except screen, to have special efficacy to eye diseases such as myopia, presbyopia, muscae volitantes, tearing against wind unclean depending on object.
The usage and the course for the treatment of of treatment myopia and presbyopic Traditional Chinese medicine eye drop of the invention are as follows:
The drop medicine interval time of eyedrops of the invention is not particularly limited, patient can take the circumstances into consideration to select according to own situation Select spraying times.Can usually drip primary, can also drip daily three times every three hours, only drip daily 1 time can also, each every eye 1- 2 drops.30 days as a treatment course.One course for the treatment of of general patient can be effective, and two to three courses for the treatment of can cure.The medication interval time It is not particularly limited, patient can take the circumstances into consideration to select times for spraying according to own situation, can also usually use daily using three times daily Once.
Based on the above technical solution, the present invention can also be improved as follows.
Further, it is made of the raw material of following parts by weight: being made of the raw material of following parts by weight: 20 parts of cassia seed, 55 parts of honeysuckle, 85 parts of pipewort, 50 parts of roxburgh anoectochilus terminal bud, 15 parts of wolfberry leaf, 50 parts of butterflybush flower, 20 parts of the coptis, 45 parts of Herba Cistanches, lock Sun 25 parts, mulberries 50 parts, 10 parts of red ginseng, 45 parts of Semen Cuscutae, 5 parts of snake bile, 40 parts of cordyceps flower, 20 parts of peppermint, 10 parts of borax, 20 parts and 500 parts of honey of the seed of feather cockscomb
Further, it is made of the raw material of following parts by weight: 32 parts of cassia seed, 60 parts of honeysuckle, 70 parts of pipewort, gold thread 40 parts of lotus, 25 parts of fructus lycii, 40 parts of butterflybush flower, 40 parts of the coptis, 50 parts of Herba Cistanches, 35 parts of cynomorium songaricum, mulberries 35 parts, 20 parts of red ginseng, 32 parts of Semen Cuscutae, 7 parts of snake bile, 32 parts of cordyceps flower, 28 parts of peppermint, 15 parts of borax, 25 parts of the seed of feather cockscomb and 450 parts of honey.
Further, it is made of the raw material of following parts by weight: 45 parts of cassia seed, 50 parts of honeysuckle, 90 parts of pipewort, gold thread 30 parts of lotus, 40 parts of wolfberry leaf, 30 parts of butterflybush flower, 30 parts of the coptis, 35 parts of Herba Cistanches, 45 parts of cynomorium songaricum, mulberries 20 parts, red ginseng 30 Part, 20 parts of Semen Cuscutae, 10 parts of snake bile, 25 parts of cordyceps flower, 35 parts of peppermint, 10 parts of borax, 20 parts of the seed of feather cockscomb and 400 parts of honey.
The second object of the present invention is to provide the preparation method of above-mentioned treatment myopia and presbyopic Traditional Chinese medicine eye drop.This The treatment myopia of invention and the preparation method of presbyopic Traditional Chinese medicine eye drop are simple, low in cost, and Chinese medicine passes through hot fermentation Afterwards, beneficial bacterium, multichain enzyme can be generated, enteron aisle is easier to absorb, and the drug effect of Chinese medicine can increase 5 times or more, and wide market is fitted Close large-scale production.
The technical scheme to solve the above technical problems is that a kind of treat myopia and presbyopic Traditional Chinese medicine eye drop Preparation method, include the following steps:
Step 1: the raw material for taking following parts by weight to clean and drying: 40-70 parts of honeysuckle, 30-50 parts of roxburgh anoectochilus terminal bud, close illiteracy 30-50 parts of flower, 20-45 parts of Semen Cuscutae and 25-40 parts of cordyceps flower, after mixing, heating fermentation ferments 36-48 hours, obtains medicinal Bacterium solution;
Step 2: the raw material for taking following parts by weight to clean and drying: 20-45 parts of cassia seed, 50-90 parts of pipewort, fructus lycii 15-40 parts of leaf, 20-50 parts of the coptis, 35-55 parts of Herba Cistanches, 25-45 parts of cynomorium songaricum, mulberries are 20-50 parts sub-, 10-30 parts of red ginseng, thin After mixing, the purified water of above-mentioned medicinal material 8-10 times of weight is added, greatly in 20-35 parts of lotus, 10-30 parts of borax and 10-30 parts of the seed of feather cockscomb Fire turns small fire and decocts 30min-45min after boiling, filtrate is collected in filtering, and rotary evaporation obtains Chinese medicine liquid:
Step 3: the Chinese medicine liquid that step 2 is obtained is added in the medicinal bacterium solution that step 1 obtains, and is fermented 12-18 hours, mistake Filter, obtains medicinal fungus original liquid;
Step 4: taking the raw material of following parts by weight: 5-10 parts and honey 300-500 parts of snake bile, being uniformly mixed, then The medicinal fungus original liquid that step 3 obtains is added, filtering sterilizes to get the treatment myopia and presbyopic Traditional Chinese medicine eye drop is arrived.
Based on the above technical solution, the present invention can also be improved as follows.
Further, in step 1 and step 3, the temperature of the fermentation is 25 DEG C -33 DEG C.
Further, in step 4, the snake bile is derived from fresh snake gall.
Further, in step 4, the filtering uses microporous membrane device, and micropore size is 0.3 μm -3 μm.
Further, in step 4, the sterilizing uses Co 60 ray, dosage 8KGY-12KGY.
Beneficial effects of the present invention:
(1) treatment myopia and presbyopic Traditional Chinese medicine eye drop of the invention are pure Chinese medicine eye, without any non-natural change It studies point, is mainly used for treating myopia, presbyopia, muscae volitantes, regards the eye diseases such as the unclean, tearing against wind of object, effect is good, expense Low, short treating period.
(2) each drug for the treatment of myopia of the invention and presbyopic Chinese medicine reaches benefit jointly after compatibility acts synergistically The effect of stomach tonifying spleen, promoting blood circulation and removing obstruction in channels, improving eyesight of enriching blood, the barrier that disappears are except screen is grown in liver, kidney tonifying.
(3) preparation method for the treatment of myopia of the invention and presbyopic Traditional Chinese medicine eye drop is simple, low in cost, before market Scape is wide, is suitble to large-scale production.
Specific embodiment
Principles and features of the present invention are described below in conjunction with specific embodiment, example is served only for explaining this hair It is bright, it is not intended to limit the scope of the present invention.
Embodiment 1
The treatment myopia and presbyopic Traditional Chinese medicine eye drop of the present embodiment, are made: cassia seed of the raw material of following weight 20kg, honeysuckle 55kg, pipewort 85kg, roxburgh anoectochilus terminal bud 50kg, wolfberry leaf 15kg, butterflybush flower 50kg, coptis 20kg, Herba Cistanches 45kg, cynomorium songaricum 25kg, the sub- 50kg of mulberries, red ginseng 10kg, Semen Cuscutae 45kg, snake bile 5kg, cordyceps flower 40kg, peppermint 20kg, boron Sand 10kg, seed of feather cockscomb 20kg and honey 500kg.
The preparation method of above-mentioned treatment myopia and presbyopic Traditional Chinese medicine eye drop, includes the following steps:
Step 1: the raw material for taking following weight to clean and drying: honeysuckle 55kg, roxburgh anoectochilus terminal bud 50kg, butterflybush flower 50kg, Tu The sub- 45kg and cordyceps flower 40kg of silk, after mixing, heating fermentation ferments 36 hours in 30 DEG C, obtains medicinal bacterium solution;
Step 2: the raw material for taking following weight to clean and drying: cassia seed 20kg, pipewort 85kg, wolfberry leaf 15kg, Huang Even 20kg, Herba Cistanches 45kg, cynomorium songaricum 25kg, the sub- 50kg of mulberries, red ginseng 10kg, peppermint 20kg, borax 10kg and seed of feather cockscomb 20kg, After mixing, the purified water of above-mentioned 8 times of weight of medicinal material is added, turns small fire after being boiled by fire and decocts 40min, filtrate, rotation are collected in filtering Turn evaporation, obtain Chinese medicine liquid:
Step 3: the Chinese medicine liquid that step 2 is obtained is added in the medicinal bacterium solution that step 1 obtains, small in 30 DEG C of fermentations 15 When, filtering obtains medicinal fungus original liquid;
Step 4: take the raw material of following weight: the snake bile 5kg and honey 500kg extracted out in fresh snake gall, mixing are equal It is even, the medicinal fungus original liquid that step 3 obtains then is added, is filtered using microporous membrane device, micropore size is 0.3 μm, using agent To get to treatment myopia and presbyopic Traditional Chinese medicine eye drop after the Co 60 ray sterilizing that amount is 8KGY.
Embodiment 2
The treatment myopia and presbyopic Traditional Chinese medicine eye drop of the present embodiment, are made: cassia seed of the raw material of following weight 32kg, honeysuckle 60kg, pipewort 70kg, roxburgh anoectochilus terminal bud 40kg, fructus lycii 25kg, butterflybush flower 40kg, coptis 40kg, Herba Cistanches 50kg, cynomorium songaricum 35kg, the sub- 35kg of mulberries, red ginseng 20kg, Semen Cuscutae 32kg, snake bile 7kg, cordyceps flower 32kg, peppermint 28kg, boron Sand 15kg, seed of feather cockscomb 25kg and honey 450kg.
The preparation method of above-mentioned treatment myopia and presbyopic Traditional Chinese medicine eye drop, includes the following steps:
Step 1: the raw material for taking following weight to clean and drying: honeysuckle 60kg, roxburgh anoectochilus terminal bud 40kg, butterflybush flower 40kg, Tu The sub- 32kg and cordyceps flower 32kg of silk, after mixing, heating fermentation ferments 48 hours in 28 DEG C, obtains medicinal bacterium solution;
Step 2: the raw material for taking following weight to clean and drying: cassia seed 32kg, pipewort 70kg, wolfberry leaf 25kg, Huang Even 40kg, Herba Cistanches 50kg, cynomorium songaricum 35kg, the sub- 35kg of mulberries, red ginseng 20kg, peppermint 28kg, borax 15kg and seed of feather cockscomb 25kg, After mixing, the purified water of above-mentioned 9 times of weight of medicinal material is added, turns small fire after being boiled by fire and decocts 35min, filtrate, rotation are collected in filtering Turn evaporation, obtain Chinese medicine liquid:
Step 3: the Chinese medicine liquid that step 2 is obtained is added in the medicinal bacterium solution that step 1 obtains, small in 32 DEG C of fermentations 12 When, filtering obtains medicinal fungus original liquid;
Step 4: take the raw material of following weight: the snake bile 7kg and honey 500kg extracted out in fresh snake gall, mixing are equal It is even, the medicinal fungus original liquid that step 3 obtains then is added, is filtered using microporous membrane device, micropore size is 2 μm, using dosage To arrive the treatment myopia and presbyopic Traditional Chinese medicine eye drop after the Co 60 ray sterilizing of 10KGY.
Embodiment 3
The treatment myopia and presbyopic Traditional Chinese medicine eye drop of the present embodiment, are made: cassia seed of the raw material of following weight 45kg, honeysuckle 50kg, pipewort 90kg, roxburgh anoectochilus terminal bud 30kg, wolfberry leaf 40kg, butterflybush flower 30kg, coptis 30kg, Herba Cistanches 35kg, cynomorium songaricum 45kg, the sub- 20kg of mulberries, red ginseng 30kg, Semen Cuscutae 20kg, snake bile 10kg, cordyceps flower 25kg, peppermint 35kg, Borax 10kg, seed of feather cockscomb 20kg and honey 400kg.
The preparation method of above-mentioned treatment myopia and presbyopic Traditional Chinese medicine eye drop, includes the following steps:
Step 1: the raw material for taking following weight to clean and drying: honeysuckle 50kg, roxburgh anoectochilus terminal bud 30kg, butterflybush flower 30kg, Tu The sub- 20kg and cordyceps flower 25kg of silk, after mixing, heating fermentation ferments 40 hours in 30 DEG C, obtains medicinal bacterium solution;
Step 2: the raw material for taking following weight to clean and drying: cassia seed 45kg, pipewort 90kg, wolfberry leaf 40kg, Huang Even 30kg, Herba Cistanches 35kg, cynomorium songaricum 45kg, the sub- 20kg of mulberries, red ginseng 30kg, peppermint 35kg, borax 10kg and seed of feather cockscomb 20kg, After mixing, the purified water of above-mentioned 10 times of weight of medicinal material is added, turns small fire after being boiled by fire and decocts 45min, filtrate is collected in filtering, Rotary evaporation obtains Chinese medicine liquid:
Step 3: the Chinese medicine liquid that step 2 is obtained is added in the medicinal bacterium solution that step 1 obtains, small in 30 DEG C of fermentations 12 When, filtering obtains medicinal fungus original liquid;
Step 4: take the raw material of following weight: the snake bile 10kg and honey 300kg extracted out in fresh snake gall, mixing are equal It is even, the medicinal fungus original liquid that step 3 obtains then is added, is filtered using microporous membrane device, micropore size is 3 μm, using dosage To arrive the treatment myopia and presbyopic Traditional Chinese medicine eye drop after the Co 60 ray sterilizing of 12KGY.
Clinical example 1
Lee, 48 years old, male, Guizhou people from Kweiyang, patient's private prosecution the first half eyes nearby regarded the unclean no headache of object and dizziness, nothing Eye pain that eye is swollen.Not to treatment, a nearly month exacerbation of symptoms.Near vision test: right eye 0.3, left eye 0.4 are corrected defects of vision: right eye+ 50DS=1.0, left eye+200DS=1.0, distant vision test: right eye 1.0, nearly small conjunctiva is normal for eye, corneal transparency, Qian Fangchang Deep, aqueous humor is clean, 3 × 3mm of building hole, slightly muddy to light reflection (+) crystal, and eyeground optic disk circle is clear, and nethike embrane advises shape blood point and exudation, yellow Spot foveal reflex is normal at (+) eyeground.Caligation before medication, the treatment myopia obtained using the embodiment of the present invention 1 and old The Traditional Chinese medicine eye drop of presbyopia, after a course for the treatment of, it is clear compared with before medication nearby to regard object for right eye 0.55, left eye 0.55.
Clinical example 2
Liu, 65 years old, male, zunyi, guizhou people, nearby blurring of vision no headache and the dizziness of patient's private prosecution the first two years eyes, nothing Eye pain that eye is swollen.Not to treatment, nearly half a year exacerbation of symptoms.Near vision test: right eye 0.4, left eye 0.5 are corrected defects of vision: right eye+ 200DS=1.0, left eye+200DS=1.0.Distant vision tests right eye 1.0, and the small conjunctiva of eyelid is normal, corneal transparency, Qian Fangchang Deep, aqueous humor is clear, 3 × 3mm of building hole, slightly muddy to light reflection (+) crystal, and eyeground optic disk circle is clear, and nethike embrane advises shape blood point and exudation, yellow Spot foveal reflex is normal at (+) eyeground.Caligation before medication, the treatment myopia obtained using the embodiment of the present invention 2 and old The Traditional Chinese medicine eye drop of presbyopia, after a course for the treatment of, right eye 0.6, left eye 0.65, eyesight is obviously improved.
Clinical example 3
Liu, 59 years old, female, patient's private prosecution the first five years eyes nearby blurring of vision can nearby have a headache and dizzy depending on object is long, Eye pain that anophthalmia is swollen.Not to treatment, nearly half a year exacerbation of symptoms.Near vision test: right eye 0.35, left eye 0.35 are corrected defects of vision: right eye + 50DS=1.0, left eye+50DS=1.0.Distant vision test: right eye 1.0, nearly small conjunctiva is normal for eye, corneal transparency, Qian Fangchang Deep, aqueous humor is clear, 3 × 3mm of pupil, slightly muddy to light reflection (+) crystal, and eyeground optic disk circle is clear, C/D=0.3, A:V=2:3, net Film advises shape blood point and exudation, and it is normal that central fovea of macula is reflected into (+) eyeground.Caligation before medication, using the embodiment of the present invention 3 Obtained treatment myopia and presbyopic Traditional Chinese medicine eye drop, after a course for the treatment of, right eye 0.75, left eye 0.75, eyesight is obviously clear.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (9)

1. a kind of treat myopia and presbyopic Traditional Chinese medicine eye drop, which is characterized in that be made of the raw material of following parts by weight: certainly 20-45 parts of pine torch, 40-70 parts of honeysuckle, 50-90 parts of pipewort, 30-50 parts of roxburgh anoectochilus terminal bud, 15-40 parts of wolfberry leaf, butterflybush flower 30- 50 parts, 20-50 parts of the coptis, 35-55 parts of Herba Cistanches, 25-45 parts of cynomorium songaricum, mulberries are 20-50 parts sub-, 10-30 parts of red ginseng, Semen Cuscutae 20-45 parts, 5-10 parts of snake bile, 25-40 parts of cordyceps flower, 20-35 parts of peppermint, 10-20 parts of borax, 10-30 parts of the seed of feather cockscomb and bee It is 300-500 parts sweet.
2. treatment myopia according to claim 1 and presbyopic Traditional Chinese medicine eye drop, which is characterized in that by following parts by weight Several raw materials are made: 20 parts of cassia seed, 55 parts of honeysuckle, 85 parts of pipewort, 50 parts of roxburgh anoectochilus terminal bud, 15 parts of wolfberry leaf, butterflybush flower 50 Part, 20 parts of the coptis, 45 parts of Herba Cistanches, 25 parts of cynomorium songaricum, mulberries 50 parts, 10 parts of red ginseng, 45 parts of Semen Cuscutae, 5 parts of snake bile, cordyceps sinensis Spend 40 parts, 20 parts of peppermint, 10 parts of borax, 20 parts of the seed of feather cockscomb and 500 parts of honey.
3. treatment myopia according to claim 1 and presbyopic Traditional Chinese medicine eye drop, which is characterized in that by following parts by weight Several raw materials are made: 32 parts of cassia seed, 60 parts of honeysuckle, 70 parts of pipewort, 40 parts of roxburgh anoectochilus terminal bud, 25 parts of fructus lycii, 40 parts of butterflybush flower, 40 parts of the coptis, 50 parts of Herba Cistanches, 35 parts of cynomorium songaricum, mulberries 35 parts, 20 parts of red ginseng, 32 parts of Semen Cuscutae, 7 parts of snake bile, cordyceps flower 32 parts, 28 parts of peppermint, 15 parts of borax, 25 parts of the seed of feather cockscomb and 450 parts of honey.
4. treatment myopia according to claim 1 and presbyopic Traditional Chinese medicine eye drop, which is characterized in that by following parts by weight Several raw materials are made: 45 parts of cassia seed, 50 parts of honeysuckle, 90 parts of pipewort, 30 parts of roxburgh anoectochilus terminal bud, 40 parts of wolfberry leaf, butterflybush flower 30 Part, 30 parts of the coptis, 35 parts of Herba Cistanches, 45 parts of cynomorium songaricum, mulberries 20 parts, 30 parts of red ginseng, 20 parts of Semen Cuscutae, 10 parts of snake bile, worm 25 parts of the showy flowers of herbaceous plants, 35 parts of peppermint, 10 parts of borax, 20 parts of the seed of feather cockscomb and 400 parts of honey.
5. a kind of preparation method for treating myopia and presbyopic Traditional Chinese medicine eye drop, which comprises the steps of:
Step 1: the raw material for taking following parts by weight to clean and drying: 40-70 parts of honeysuckle, 30-50 parts of roxburgh anoectochilus terminal bud, butterflybush flower 30-50 parts, 20-45 parts of Semen Cuscutae and 25-40 parts of cordyceps flower, after mixing, heating fermentation ferments 36-48 hours, obtains medicinal fungus Liquid;
Step 2: the raw material for taking following parts by weight to clean and drying: 20-45 parts of cassia seed, 50-90 parts of pipewort, wolfberry leaf 15-40 parts, 20-50 parts of the coptis, 35-55 parts of Herba Cistanches, 25-45 parts of cynomorium songaricum, mulberries are 20-50 parts sub-, 10-30 parts of red ginseng, peppermint After mixing, the purified water of above-mentioned medicinal material 8-10 times of weight, high fire is added in 20-35 parts, 10-20 parts of borax and 10-30 parts of the seed of feather cockscomb Turn small fire after boiling and decoct 30min-45min, filtrate is collected in filtering, and rotary evaporation obtains Chinese medicine liquid:
Step 3: the Chinese medicine liquid that step 2 is obtained is added in the medicinal bacterium solution that step 1 obtains, and is fermented 12-18 hours, filtering, Obtain medicinal fungus original liquid;
Step 4: taking the raw material of following parts by weight: 5-10 parts and honey 300-500 parts of snake bile, being uniformly mixed, be then added The medicinal fungus original liquid that step 3 obtains, filtering sterilize to get the treatment myopia and presbyopic Traditional Chinese medicine eye drop is arrived.
6. the preparation method for the treatment of myopia and presbyopic Traditional Chinese medicine eye drop according to claim 5, which is characterized in that step Rapid 1 and step 3 in, the temperature of the fermentation is 25 DEG C -33 DEG C.
7. the preparation method for the treatment of myopia and presbyopic Traditional Chinese medicine eye drop according to claim 5, which is characterized in that step In rapid 4, the snake bile is derived from fresh snake gall.
8. the preparation method for the treatment of myopia and presbyopic Traditional Chinese medicine eye drop according to claim 5, which is characterized in that step In rapid 4, the filtering uses microporous membrane device, and micropore size is 0.3 μm -3 μm.
9. the preparation method for the treatment of myopia and presbyopic Traditional Chinese medicine eye drop according to claim 5, which is characterized in that step In rapid 4, the sterilizing uses Co 60 ray, dosage 8KGY-12KGY.
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Publication number Priority date Publication date Assignee Title
CN102188604A (en) * 2010-03-09 2011-09-21 贺光民 Medicament for treating myopia and presbyopia
CN106344827A (en) * 2016-09-28 2017-01-25 广西大学 Eye drops for treating presbyopia and preparation method of eye drops
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Publication number Priority date Publication date Assignee Title
CN102188604A (en) * 2010-03-09 2011-09-21 贺光民 Medicament for treating myopia and presbyopia
CN106344827A (en) * 2016-09-28 2017-01-25 广西大学 Eye drops for treating presbyopia and preparation method of eye drops
CN107802707A (en) * 2017-11-15 2018-03-16 高金水 A kind of Chinese medicine composition for treating children's pseudo-myopia and preparation method thereof

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