CN109596852B - Sample analyzer, sample detection device, and sample detection method - Google Patents
Sample analyzer, sample detection device, and sample detection method Download PDFInfo
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- CN109596852B CN109596852B CN201710939351.2A CN201710939351A CN109596852B CN 109596852 B CN109596852 B CN 109596852B CN 201710939351 A CN201710939351 A CN 201710939351A CN 109596852 B CN109596852 B CN 109596852B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0474—Details of actuating means for conveyors or pipettes
- G01N2035/0491—Position sensing, encoding; closed-loop control
Abstract
The invention provides a sample analysis device which comprises a substrate, a detection unit and an objective table, wherein a first detection track and a second detection track are arranged on the objective table. The invention also provides sample detection equipment and a sample detection method. According to the embodiment of the invention, the first detection track and the second detection track which are arranged in parallel are arranged, after the detection of the submission sample on one detection track is finished, the submission sample on the other detection track is detected, and if the prior submission sample does not need to be retested, the subsequent submission sample can be continuously detected; if the prior sample needs to be rechecked, the relative positions of the object stage and the detection unit can be adjusted by the displacement device to recheck the prior sample. Continuous detection of samples to be inspected is guaranteed, extra workload is not wasted, and the samples to be inspected are saved and sorted, so that the samples to be inspected can be inspected conveniently and quickly.
Description
Technical Field
The invention relates to the technical field of detection, in particular to a sample analysis device, sample detection equipment and a sample detection method.
Background
In order to know the health condition of a human body, it may be necessary to detect samples of blood, sweat, hair, secretions and excretions from the human body during clinical medical diagnosis, physical examination, etc. so as to know the health condition of the human body. The existing detection mode can not conveniently and quickly carry out retest on a to-be-retested sample.
Disclosure of Invention
Therefore, it is necessary to provide a convenient and fast sample analysis device, a sample detection device and a sample detection method for solving the problem that the existing retest method cannot conveniently and fast retest the to-be-retested sample.
A sample analysis device, comprising:
a substrate on which a detection site is disposed;
the detection unit corresponds to the detection position and is used for acquiring the sample information of the to-be-detected sample on the detection position;
the objective table is movably arranged on the substrate, a first detection track and a second detection track are arranged on the objective table, and the samples to be inspected can be accommodated in the first detection track or the second detection track;
the object stage can move back and forth relative to the substrate, so that the first detection track and the second detection track are alternately positioned on the detection position.
In one embodiment, the detection unit is one or more of an image detection module, a physical detection module, a chemical detection module and a biological analysis module.
In addition, this application still provides a sample test equipment, includes:
a sample analysis device as claimed in any one of the preceding claims;
the pushing device is arranged corresponding to the detection position and is in communication connection with the detection unit, and the pushing device can execute pushing action so as to push the to-be-detected sample into the first detection track or the second detection track on the detection position;
when the first detection track or the second detection track where the sample to be repeatedly detected is located moves to the detection position, the pushing device suspends the pushing action; the sample to be retested is the censored sample of which the sample information meets the preset condition.
In one embodiment, the device further comprises a conveying device for conveying the censored sample to the position between the detection position and the pushing device.
In one embodiment, the delivery device comprises:
a carrier cassette for storing a carrier for containing a sample for submission;
the conveying piece is used for conveying the carrier containing the inspection sample to a position between the pushing device and the objective table;
and the carrier pushing-out part is used for pushing the carrier out of the carrier box to the conveying part.
In one embodiment, the device further comprises a waste material box, wherein the waste material box is arranged on one side of the object stage far away from the pushing device and is opposite to the detection position.
In one embodiment, the sample feeding device is further included, and the sample feeding device is used for diluting the sample to be detected according to a preset mode.
In addition, the present application also provides a sample detection method applied to the sample detection apparatus described in any one of the above, the sample detection method comprising the steps of:
pushing an A-th submission sample to the first detection track through the pushing device, and detecting the A-th submission sample by using the detection unit;
after the detection of the A < th > submission sample is finished, pushing the A < th > and +1 < th > submission sample to the second detection track, so as to detect the A < th > and +1 < th > submission sample by using the detection unit, simultaneously obtain the detection result of the A < th > and judge whether the A < th > submission sample needs to be retested, wherein the second detection track is positioned on the detection position;
when the A < th > submission sample needs to be retested, after the A +1 < th > submission sample is detected, the first detection track is moved to the detection position, and the A < th > submission sample is retested by the detection unit.
In one embodiment, the method further comprises the following steps:
when the retest of the A-th submission sample is not needed, the pushing device pushes the A-th submission sample out of the first detection track and pushes the A + 2-th submission sample to the first detection track, and at the moment, the first detection track is located on the detection position.
In one embodiment, the step of determining whether the retest of the inspection sample a is required includes:
judging whether the detection result of the A-th submission sample is positive or not; or
And judging whether a retest request aiming at the A-th submission sample is received or not.
According to the embodiment of the invention, the first detection track and the second detection track which are arranged in parallel are arranged, after the detection of the sample to be detected on one detection track is finished, the relative positions of the detection unit and the objective table are adjusted to detect the sample to be detected on the other detection track in the period of waiting for the detection result, the sample to be detected is located on the detection track in the process of waiting for the detection result of the sample to be detected and detecting the current sample to be detected, and if the detection result of the sample to be detected does not need to be re-detected, the subsequent sample to be detected can be moved to the detection track where the sample to be detected is located and replaces the position of the sample to be detected; if the samples which are sent for inspection in advance need to be inspected again, the relative positions of the object stage and the detection unit can be adjusted through the displacement device so as to inspect the samples which are sent for inspection in advance again. Continuous detection of the submission samples to be inspected is guaranteed, extra workload is not wasted, the submission samples to be detected are saved and sorted, and the submission samples to be inspected are convenient and quick to inspect again.
Drawings
FIG. 1 is a schematic structural diagram of a sample testing device according to an embodiment of the present invention;
FIG. 2 is a flowchart of a real-time review method according to an embodiment of the present invention;
FIG. 3 is a flowchart of a real-time review method according to another embodiment of the present invention;
FIG. 4 is a flowchart illustrating a detailed process of determining whether a first sample needs to be reviewed in one embodiment;
FIG. 5 is a flowchart illustrating a detailed process for determining whether the first sample needs to be reviewed in accordance with yet another embodiment.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
The invention provides a sample analyzer.
It should be understood that the sample detection device in the present embodiment can detect samples such as blood, sweat, hair, secretion and excrement of human body and animals, obviously, the application field of the sample detection device is not limited to this, for example, the sample detection device can be widely applied to various occasions where food, chemical fiber, water quality state, soil condition and the like need to be detected and the retest of the samples to be detected is possible. In this embodiment, the present invention is described by taking an example of application to detection of a blood sample.
Referring to fig. 1, in an embodiment, the sample testing apparatus includes a testing unit 10, a stage 20 and a testing track 30, and the sample testing apparatus further defines a testing position within which a sample to be tested is tested.
The detecting unit 10 in this embodiment may be an image detecting module, and specifically may be an image collecting unit including a CCD (Charge-coupled Device) image sensor or a CMOS (Complementary Metal Oxide Semiconductor) image sensor, and in a using process, the image collecting module collects an image of a sample to be detected and compares the collected image with an image of a standard sample, so as to obtain a detection result, and further, the detecting unit may further analyze the collected image and compare the analysis result with the standard sample, so as to obtain a detection result for the current sample to be detected.
The type of the detecting unit 10 in this embodiment is not the invention of the present invention, so that various existing or improved detecting units 10 and their combinations, such as one or more of a physical detecting module, a chemical detecting module and a biological analyzing module, can be selected according to specific situations and detecting items.
The stage 20 in the present embodiment is disposed corresponding to the detecting unit 10, and during use, the carrier 110 containing the sample to be tested is disposed on the stage 20, and the sample to be tested is detected by the detecting unit 10.
Specifically, the carrier 110 is disposed in the detection rail 30 on the stage 20. The shape of the detection track 30 in this embodiment matches the shape of the carrier 110 carrying the sample to be detected, it should be understood that the sample to be detected is carried by the corresponding carrier 110 during the detection process, for example, in the routine detection of blood, a blood sample is collected by a blood sampling bottle, and further the slide is used as the carrier 110 to place the blood sample on the detector for detection, the shape and size of the corresponding guide rail need to match the shape and size of the slide used, so that the slide can slide in the detection track 30.
In this embodiment, the number of the detection tracks 30 should be at least two, and the number of the detection tracks 30 needs to be selectively set according to a specific usage scenario and a specific detection item targeted by the sample detection device. For example, if a specific user of the apparatus is a large medical center that undertakes testing of blood samples of a large number of patients, in order to improve the testing efficiency, it is necessary to relatively increase the number of testing rails 30, for example, ten testing rails 30. If the particular user of the apparatus is a small or medium-sized hospital, and the number of patients and the number of blood samples to be taken for examination are relatively small, the number of examination tracks 30 to be provided can be reduced, for example, only three examination tracks 30 are provided.
In some embodiments, if the waiting period of the detection result is longer, the number of detection tracks 30 may be increased to some extent. For example, two minutes are required for the detection process of a certain detection item, and six minutes are required for the process of waiting for the detection result after the detection is completed, so that continuous detection can be realized if only two detection tracks 30 are provided, but only four minutes are required for completing the detection of the samples to be detected on the two detection tracks 30, and at this time, two minutes are required for obtaining the detection result of the samples to be detected in advance, which results in a blank period of two minutes, affects the detection efficiency to a certain extent, and continuous detection of the samples to be detected can be realized if three detection tracks 30 are provided. In addition, in consideration of the time required for the processes such as switching the detecting unit 10, it is preferable to provide four or more detecting tracks 30 in the present embodiment, so as to implement seamless connection of the detecting processes of a plurality of samples to be detected. Obviously, if the time required for the process of waiting for the detection result is less than the detection time, for example, the detection process requires two minutes, and the waiting for the detection result requires only one minute, the detection result of the previous sample can be obtained during the detection process of the second sample, so that only two detection tracks 30 are required to achieve seamless connection of the detection process.
In the present embodiment, the first detection track 30A and the second detection track 30B are provided as an example, and it is obvious that if a plurality of detection tracks 30 are provided, the operation principle is the same as that of two detection tracks 30.
In a preferred embodiment, the two detection tracks 30 are parallel to each other for ease of handling and positioning. Obviously, in other embodiments, the detection tracks 30 are not parallel to each other, and different detection tracks 30 can be located at the detection positions.
In this embodiment, the two detection tracks 30 are arranged in parallel at the detection position on the stage 20, and during the detection process, the carrier 110 carrying the inspection sample slides to the detection position along the first detection track 30A or the second detection track 30B. When the detection device is used, the first detection track 30A and the second detection track 30B can be alternately positioned on the detection positions under the driving of the object stage 20, so as to detect the censored samples positioned on different detection tracks 30, after the censored sample on one detection track 30 is detected, for example, the censored sample on the first detection track 30A is detected, the second detection track 30B can be positioned on the detection position by moving the object stage during waiting for the detection result, so as to detect the censored sample on the second detection track 30B, during the detection of the censored sample on the second detection track 30B, the detection result of the censored sample on the first detection track 30A can be obtained, if the result is abnormal and the censored sample positioned on the first detection track 30A needs to be retested, the first detection track 30A can be moved to the detection position again by moving the object stage, thereby realizing the retest of the samples to be inspected on the first inspection track 30B.
It should be understood that the detection range of the detection unit 10 is limited in order to ensure the detection effect thereof. Taking a microscope as an example, when a microscope is used for detecting a sample to be detected, the smaller the field of view of the microscope is, the larger the field of view of the microscope is, and the larger the multiple is, the clearer the observation result is. If the field of view of the microscope is too large, the overall magnification is relatively small, and the observation effect is relatively poor. Therefore, in the technical solution of the present embodiment, in order to ensure the detection effect of the detection unit 10, the detection range is also limited, and the detection unit cannot cover a plurality of detection tracks 30 at the same time, so that a displacement device is further provided in the present embodiment to adjust the relative positions of the detection unit 10 and the object stage 20.
In one embodiment, the detecting unit 10 is fixed, the object stage 20 is moved by the moving device, in other embodiments, the object stage 20 is fixed, and the position of the detecting unit 10 can be adjusted by the moving device, so as to adjust the relative positions of the detecting unit 10 and the object stage 20, so as to detect the samples to be detected in the carriers 110 on different detecting tracks 30 by using the detecting unit 10.
The displacement device in this embodiment may be a screw rod device matching with a motor, and the motor drives the screw rod to rotate to realize position adjustment, or may be an air cylinder or an oil cylinder arranged along a preset direction, and also can realize adjustment of the relative position of the detection unit 10 and the object stage 20.
In addition, the present invention also provides a sample testing device 100. The sample testing device 100 in this embodiment includes the pushing means 40 and the sample analyzing means described above.
The pushing device 40 in this embodiment is disposed at one side of the detection track 30, and is used for pushing the carrier 110 carrying the inspection sample to the detection position along the different detection tracks 30. It should be understood that, in order to make the process of pushing the carrier 110 more smooth, the pushing member of the pushing device 40 is bar-shaped or column-shaped and has a size matched with the detection track 30 so as to push the carrier 110 to a designated position of the detection position along the detection track 30 and further perform the detection. In addition, since there are a plurality of detection tracks 30, the relative position between the pushing device 40 and the object stage 20 provided with the detection tracks 30 is not fixed during each pushing process, and the relative position between the pushing device 40 and the object stage 20 should be adjusted for the detection tracks 30 where the carrier 110 is located during each pushing process.
In one embodiment, the pushing device 40 is fixed on a substrate, and the substrate can move within a small range under the driving of the driver. In a specific using process, when a sample needs to be pushed onto the first detection track 30A, the substrate is driven by the driver to move to the pushing device 40 to be aligned with the first detection track 30A; correspondingly, when the sample needs to be pushed onto the second detection track 30B, the substrate is driven by the driver to move to the pushing device 40 to align with the second detection track 30B, the driver in this embodiment may be an air cylinder or an oil cylinder, or may be an electric motor or a motor, and further drives the substrate to move through a transmission mechanism such as a screw rod. Obviously, in other embodiments, the pushing device 40 may be stationary, and the detection track 30 may be movable, so that the adjustment of the relative position between the pushing device 40 and the detection track 30 can be realized. In a further embodiment, the pushing device 40 is provided with a number of pushing members equal to the number of detection tracks 30, and each pushing member is dedicated to pushing the carrier 110 on the corresponding pushing track, which also enables pushing the carrier 110 carrying the inspection sample into different detection tracks 30.
In a specific use process, when the first detection track 30A or the second detection track 30B where the sample to be repeatedly detected is located moves to the detection position, the pushing device 40 suspends the pushing action. The sample to be retested is a censored sample of which the sample information meets the preset conditions, specifically, the censored sample is a censored sample of which the detection result is positive or is manually confirmed to be required to be retested. In the embodiment, by arranging a plurality of parallel detection tracks 30, after the sample on one detection track 30 is detected, and during the waiting period of the detection result, the position of the detection unit 10 is switched by using the displacement device to detect the samples to be detected on the other detection tracks 30, so that the samples to be detected are continuously detected, and the detection time is saved. Meanwhile, in the process of waiting for the detection result of the previous sample to be detected and detecting the current sample to be detected, the previous sample to be detected is located on the detection track 30, and if the detection result of the previous sample to be detected does not need to be rechecked, the subsequent sample to be detected can be pushed to the detection track 30 where the previous sample to be detected is located through the pushing device 40 and replaces the position of the previous sample to be detected; if the previously submitted sample needs to be retested, the position of the detection unit 10 can be switched back by the displacement device to retest the previously submitted sample. In the process, continuous detection of the submission samples is ensured, extra workload is not wasted for storing and sorting the submission samples of the to-be-detected results, and convenient and rapid retesting of the to-be-retested samples is realized.
Obviously, in the present embodiment, the carrier 110 may be manually placed on the detection track 30, and the carrier 110 may be pushed to a designated position by the pushing device 40. For further convenience of operation, in an embodiment, a conveying device 50 for conveying the carrier 110 is further included, the conveying device 50 is disposed between the pushing device 40 and the detecting track 30, and the pushing device 40 is used for pushing the carrier 110 on the conveying device 50 to the detecting position through the different detecting tracks 30.
The conveying device 50 in this embodiment may be a guide rail, a conveyor belt, a mechanical arm, or the like, and in this embodiment, the conveyor belt is taken as an example, and the conveyor belt is disposed between the detection track 30 and the pushing device 40. In order to save space, the conveying direction of the conveyor belt is perpendicular to the direction of the detection guide rail in this embodiment, and obviously, in some other embodiments, the conveying of the carrier 110 can be realized if the direction of the conveyor belt is not perpendicular to the direction of the detection guide rail.
In use, the belt transfers the carrier 110 carrying the sample to be tested to the end of the detection track 30, and then the pushing device 40 pushes the carrier 110 to the detection position along the corresponding detection track 30, and further completes the detection of the sample to be tested by using the detection unit 10.
In one embodiment, the sample adding device 70 is further included, and the sample adding device 70 is configured to add the sample to be tested located in the sampler to the carrier 110, and dilute the sample to be tested according to a preset manner.
It should be understood that in some assays, the sample collected is directly available for testing, while in some assays, the sample collected must be pre-processed for further testing. Obviously, for a sample which can be directly detected, the detection can be directly carried out; for the sample needing to be pretreated, the sample adding device 70 is further arranged to pretreat the collected sample in this embodiment.
In one embodiment, the sample application device 70 comprises a sample application guide 72 and a sampling member 71, wherein the sampling member 71 slides on the sample application guide 72 by being driven by an air cylinder or an oil cylinder. Generally, the samples to be tested are contained in different containers during the collection and testing processes, for example, in the case of blood sample testing, the collected blood samples are stored in a blood sampling bottle, and when the blood samples need to be further tested, the blood samples need to be transferred to other containers, such as a slide, and then further tested. In the present embodiment, the sampling member 71 is arranged to transfer the sample to be tested in the sampling container to the carrier 110. The sampling container can be various existing and improved sampling containers such as a sampling blood bottle, a urine cup and the like.
In some embodiments, to prevent cross-contamination of the sample under test, a washing device may be provided to wash the sample piece 71 after each dilution of the sample under test.
It should be understood that the sampling member 71 should be selected according to the specific detection item, and the sampling member 71 can be, but is not limited to, a sampling needle, a sampling pipette, and other existing and improved sampling tools. In one embodiment, the sample testing device is used to test a blood sample, and the corresponding sampling member 71 uses a sampling pipette to draw the blood sample from the sampling blood bottle and drop it onto the slide. It will be appreciated that in this embodiment, the detection of a blood sample is aimed at, so the sample member 71 is a sample tube and the carrier 110 is a slide. In other embodiments, the adjustment should be made specifically, for example, if a sample of excrement is to be detected, the sampling member 71 should select the sampling needle accordingly.
In order to facilitate the taking of a sample to be tested from a sampling container by using the sampling member 71, a sample feeding device 80 and a carrier output device 90 are further provided in the present embodiment. The sample feeding device 80 is used for transporting the sampling container containing the sample to be tested to a designated position, so that the sample feeding device 70 can obtain the sample to be tested in the sampling container. The carrier output device 90 includes a carrier storage box 91 for storing the carrier 110 and a carrier guide 92 for conveying the carrier 110, and is specifically configured to convey the empty carrier 110 in the carrier storage box 91 to a designated position, so that the sample adding device 70 can add the sample to be tested in the sample container onto the carrier 110.
In an embodiment, in order to facilitate recycling of the inspected samples and carriers 110, a waste material box 60 is further provided, in this embodiment, the waste material box 60 is disposed on one side of the inspection track 30 away from the pushing device 40, when a new carrier 110 is pushed to the inspection position by the pushing device 40 along the inspection track 30, the new carrier 110 ejects the carrier 110 located on the inspection position to be separated from the inspection track 30 and falls into the waste material box 60, thereby completing recycling of the inspected samples and carriers 110.
In one embodiment, in order to count the number of detected samples, a counting sensor (not shown) is further provided, and the counting sensor cooperates with the pushing device 40 to count the number of detected samples by counting the pushing times of the pushing device 40.
The counting sensor in this embodiment may be a photoelectric sensor, and includes a transmitter and a receiver disposed on two sides of a pushing rod or a pushing plate of the pushing device 40, when the pushing device 40 executes a pushing action, the pushing rod or the pushing plate blocks or avoids an optical signal sent by the transmitter during a moving process, and the receiver may count the number of times of pushing according to the received optical signal, so as to obtain the number of detected samples to be inspected.
In addition, in order to achieve the above object, the present invention further provides a real-time review method, which is applied to any one of the above sample testing devices.
Referring to fig. 2, in one embodiment, the method includes the steps of:
s10, pushing the a-th test sample to the first detection track 30A by the pushing device 40, and detecting the a-th test sample by the detection unit 10;
s20, after the detection of the a-th submission sample is completed, pushing the a + 1-th submission sample to the second detection track 30B, so as to detect the a + 1-th submission sample by using the detection unit 10, obtain a detection result of the a-th submission sample, and determine whether the a-th submission sample needs to be retested, where the second detection track is located at the detection position;
s30, when the A-th submission sample needs to be retested, after the A + 1-th submission sample is detected, the first detection track is moved to the detection position, and the A-th submission sample is retested by the detection unit;
in the technical solution of this embodiment, after the pushing device 40 pushes the a-th submission sample to the detection position through the first detection track 30A, the detection unit 10 detects the a-th submission sample, and after the detection of the a-th submission sample is completed, the detection unit 10 detects the a + 1-th submission sample in the second detection track. In this embodiment, the relative positions of the object stage 20 and the detecting unit 10 may be adjusted first to move the second detecting track 30B to the detecting position, and then the a +1 th sample to be detected is pushed into the second detecting track 30B, or the a +1 th sample to be detected is pushed into the second detecting track 30B, and then the relative positions of the object stage 20 and the detecting unit 10 are adjusted to position the second detecting track 30B on the detecting position.
In the process of detecting the A +1 th submission sample, the detection result of the A th submission sample can be obtained at the same time, and whether the A th submission sample needs to be rechecked or not is judged, so that the detection process is continuously carried out, and the phenomenon that the detection is interrupted and the time is wasted when the A +1 th submission sample is waited is avoided.
If the A-th submission sample needs to be retested, after the A + 1-th submission sample is detected, the relative position of the stage 20 and the detection unit 10 is adjusted, so that the first detection track 30A where the A-th submission sample is located at the detection position again, and the A-th submission sample is further retested.
Further, as shown in fig. 3, in an embodiment, the method further includes step S31:
and S31, when the retest of the A-th submission sample is not needed, pushing the A-th submission sample out of the first detection track through the pushing device, and pushing the A + 2-th submission sample to the first detection track, wherein the first detection track is located on the detection position.
It should be understood that, if the a-th inspection sample does not need to be retested, a new a + 2-th inspection sample is pushed into the first detection track 30A where the a-th inspection sample is located before, specifically, the a + 2-th inspection sample may be pushed into the first detection track 30A where the a-th inspection sample is located before, and then the relative position of the first detection track 30A and the detection unit 10 is adjusted, or the relative position of the first detection track 30A and the detection unit 10 may be adjusted first, and then the a + 2-th inspection sample is pushed into the first detection track 30A where the a-th inspection sample is located before.
According to the technical scheme of the embodiment, the continuous and uninterrupted detection of the delivery sample can be realized by circularly executing the operation, the A-th delivery sample is positioned on the first detection track 30A in the process of waiting for the detection result of the A-th delivery sample and detecting the A + 1-th delivery sample, and if the A-th delivery sample does not need to be retested, the A + 2-th delivery sample to be subsequently detected can be pushed to the first detection track 30A where the A-th delivery sample is positioned by the pushing device 40 and replaces the position of the A-th delivery sample; if the A < th > censored sample needs to be retested, the position of the detection unit 10 can be switched back by the displacement device to retest the A < th > censored sample. In the process, continuous detection of the samples to be detected is ensured, extra workload is not wasted, and the samples of the results to be detected are saved and sorted, so that the samples to be detected are detected conveniently and quickly.
As shown in fig. 4, in some embodiments, the step S20 of determining whether the retest of the inspection sample a is required includes:
s201, judging whether the detection result of the A-th censorship sample is positive or not;
s202, when the detection result of the A-th submission sample is positive, confirming that the A-th submission sample needs to be subjected to rechecking;
s203, when the detection result of the A-th submission sample is not positive, confirming that the A-th submission sample does not need to be subjected to recheck;
referring to fig. 5, in some other embodiments, in step S20, the step of determining whether the review of the inspection sample a is required may further include:
s211, judging whether a retest instruction aiming at the A-th inspection sample is received or not;
s212, when a retest instruction for the A-th submission sample is received, confirming that the A-th submission sample needs to be retested;
s213, if no review instruction for the a-th review sample is received, it is determined that the a-th review sample is not required to be reviewed.
It should be understood that, in general, if the detection result is normal, i.e. the detection result is not positive, i.e. the detection result is negative, the corresponding test sample does not need to be tested again; if the test result is abnormal, i.e., the test result is positive, it is necessary to perform further tests on the sample to determine possible problems. Obviously, in some specific cases, the determination is not necessarily accurate only according to the detection result, and it is necessary to combine with other cases to further confirm whether further review is needed, for example, an experienced physician confirms whether further review is needed for some particular problem, and in this case, whether further review is needed for a certain sample to be inspected can be confirmed according to whether there is a review instruction for the certain sample to be inspected.
The above examples only show some embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (9)
1. A sample testing device, comprising:
a sample analysis device comprising:
a substrate on which a detection site is disposed; the detection unit corresponds to the detection position and is used for acquiring sample information of the to-be-detected sample on the detection position;
the object stage is movably arranged on the substrate, a first detection track and a second detection track are arranged on the object stage, and the samples to be inspected can be accommodated on the first detection track or the second detection track;
the object stage can reciprocate relative to the substrate, so that the first detection track and the second detection track are alternately positioned on the detection position;
the pushing device is arranged corresponding to the detection position and is in communication connection with the detection unit, and the first detection track and the second detection track alternately correspond to the pushing device in the process that the objective table moves back and forth relative to the substrate;
the pushing device can execute a pushing action to push out the current inspection sample on the corresponding first detection track or the second detection track and push the next inspection sample into the corresponding first detection track or the second detection track;
when the first detection track or the second detection track where the sample to be repeatedly detected is located moves to the detection position, the pushing device suspends the execution of the pushing action; the sample to be retested is the censored sample of which the sample information meets the preset condition.
2. The apparatus according to claim 1, wherein the detection unit is one or more of an image detection module, a physical detection module, a chemical detection module, and a biological analysis module.
3. The sample testing device of claim 1, further comprising a transport device for transporting said censored sample between said testing location and said pushing device.
4. The sample testing device of claim 3, wherein said transport means comprises:
a carrier cassette for storing a carrier for containing a sample for submission;
the conveying piece is used for conveying the carrier containing the inspection sample to a position between the pushing device and the objective table;
and the carrier pushing-out part is used for pushing the carrier out of the carrier box to the conveying part.
5. The apparatus according to claim 1, further comprising a waste box disposed on a side of the stage away from the pusher and opposite to the detection site.
6. The sample testing device of claim 1, further comprising a sample application device for diluting the sample to be tested in a predetermined pattern.
7. A sample testing method applied to the sample testing device according to any one of claims 1 to 6, the sample testing method comprising the steps of:
pushing an A-th submission sample to the first detection track through the pushing device, and detecting the A-th submission sample by using the detection unit;
after the detection of the A < th > submission sample is finished, pushing the A < th > and +1 < th > submission sample to the second detection track, so as to detect the A < th > and +1 < th > submission sample by using the detection unit, simultaneously obtain the detection result of the A < th > and judge whether the A < th > submission sample needs to be retested, wherein the second detection track is positioned on the detection position;
when the A < th > submission sample needs to be retested, after the A +1 < th > submission sample is detected, the first detection track is moved to the detection position, and the A < th > submission sample is retested by the detection unit.
8. The method for detecting a specimen according to claim 7, further comprising the steps of:
when the retest of the A-th submission sample is not needed, the pushing device pushes the A-th submission sample out of the first detection track and pushes the A + 2-th submission sample to the first detection track, and at the moment, the first detection track is located on the detection position.
9. The method for detecting a sample according to claim 7, wherein the step of determining whether the retest of the a-th specimen is required comprises:
judging whether the detection result of the A-th submission sample is positive or not; or
And judging whether a rechecking request aiming at the A-th submission sample is received.
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| CN110487795B (en) * | 2019-10-21 | 2020-02-07 | 湖南莱博赛医用机器人有限公司 | Cell analysis apparatus having two stages and control method |
| WO2022116112A1 (en) * | 2020-12-03 | 2022-06-09 | 深圳迈瑞生物医疗电子股份有限公司 | Sample analysis system and method, sample image analysis system and blood analyzer |
| CN114812395A (en) * | 2021-01-27 | 2022-07-29 | 深圳中科飞测科技股份有限公司 | Detection system and detection method |
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