CN109568338A - 用于治疗钙吸收不良和骨代谢紊乱的无定形碳酸钙 - Google Patents

用于治疗钙吸收不良和骨代谢紊乱的无定形碳酸钙 Download PDF

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Publication number
CN109568338A
CN109568338A CN201910013584.9A CN201910013584A CN109568338A CN 109568338 A CN109568338 A CN 109568338A CN 201910013584 A CN201910013584 A CN 201910013584A CN 109568338 A CN109568338 A CN 109568338A
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CN
China
Prior art keywords
calcium
acc
bone
subject
acid
Prior art date
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Pending
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CN201910013584.9A
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English (en)
Chinese (zh)
Inventor
阿米尔·萨希
阿萨夫·瑟尔特
盖利特·薛泰尔-高德
麦克·丹尼利
欧尔文·梅伦
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Amorphical Ltd
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Amorphical Ltd
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Publication of CN109568338A publication Critical patent/CN109568338A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/612Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN201910013584.9A 2011-12-13 2012-12-13 用于治疗钙吸收不良和骨代谢紊乱的无定形碳酸钙 Pending CN109568338A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161569805P 2011-12-13 2011-12-13
US61/569,805 2011-12-13
US201261680721P 2012-08-08 2012-08-08
US61/680,721 2012-08-08
CN201280069595.5A CN104114179A (zh) 2011-12-13 2012-12-13 用于治疗钙吸收不良和骨代谢紊乱的无定形碳酸钙

Related Parent Applications (1)

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CN201280069595.5A Division CN104114179A (zh) 2011-12-13 2012-12-13 用于治疗钙吸收不良和骨代谢紊乱的无定形碳酸钙

Publications (1)

Publication Number Publication Date
CN109568338A true CN109568338A (zh) 2019-04-05

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CN201910013584.9A Pending CN109568338A (zh) 2011-12-13 2012-12-13 用于治疗钙吸收不良和骨代谢紊乱的无定形碳酸钙
CN201280069595.5A Pending CN104114179A (zh) 2011-12-13 2012-12-13 用于治疗钙吸收不良和骨代谢紊乱的无定形碳酸钙

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Country Status (10)

Country Link
US (2) US10064890B2 (cg-RX-API-DMAC7.html)
EP (1) EP2790710B1 (cg-RX-API-DMAC7.html)
JP (3) JP2015500333A (cg-RX-API-DMAC7.html)
CN (2) CN109568338A (cg-RX-API-DMAC7.html)
AU (3) AU2012354056B2 (cg-RX-API-DMAC7.html)
CA (2) CA2859122C (cg-RX-API-DMAC7.html)
DK (1) DK2790710T3 (cg-RX-API-DMAC7.html)
ES (1) ES2831699T3 (cg-RX-API-DMAC7.html)
IL (2) IL233107B (cg-RX-API-DMAC7.html)
WO (1) WO2013088440A1 (cg-RX-API-DMAC7.html)

Families Citing this family (17)

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JP2016507553A (ja) * 2013-02-11 2016-03-10 アモーフィカル リミテッド. 骨成長を促進する非晶質炭酸カルシウム
EP3174409A4 (en) 2014-07-31 2018-01-17 Amorphical Ltd. Encapsulated amorphous calcium carbonate compositions
US12121538B2 (en) 2015-06-04 2024-10-22 Amorphical Ltd. Compositions of amorphous calcium carbonate for inhalation, sublingual or buccal administration
HK1253702A1 (zh) * 2015-06-04 2019-06-28 艾玛菲克有限公司 用聚磷酸/聚磷酸酯/聚磷酸盐或双膦酸/双膦酸酯/双膦酸盐稳定的无定形碳酸钙
JP2017032550A (ja) * 2015-07-30 2017-02-09 大塚製薬株式会社 胃粘膜萎縮の有無を判定する方法
ES3052833T3 (en) 2016-01-18 2026-01-15 Amorphical Ltd Stabilized amorphous calcium carbonate as a supplement for cell culture media
US20230365935A1 (en) * 2016-01-18 2023-11-16 Amorphical Ltd. Stabilized amorphous calcium carbonate as a supplement for cell culture media
JP6873389B2 (ja) 2016-01-18 2021-05-19 アモーフィカル リミテッド. 神経学的、筋肉、および不妊の疾患または症状の治療のための安定化無定形炭酸カルシウム
JP6872680B2 (ja) * 2016-03-22 2021-05-19 国立大学法人 宮崎大学 カルシウム吸収促進剤
JP7152785B2 (ja) * 2016-10-25 2022-10-13 アモーフィカル リミテッド. 白血病治療のための非晶質炭酸カルシウム
CN110123836A (zh) * 2019-05-20 2019-08-16 昆明朗盛生物科技有限公司 钙锌维生素d泛酸片的应用
IL289237B2 (en) 2019-07-23 2026-03-01 Amorphical Ltd Amorphous calcium carbonate for improving athletic performance
WO2021181372A1 (en) * 2020-03-11 2021-09-16 Amorphical Ltd. Amorphous calcium carbonate for treatment of acidosis
US20230223125A1 (en) * 2020-05-04 2023-07-13 University Of Louisville Research Foundation, Inc. Artificial intelligence-based systems and methods for dosing of pharmacologic agents
CN121731510A (zh) * 2020-09-15 2026-03-27 昂科因凡特解决方案公司 尺寸可控的放射性标记粒子
JP7573310B2 (ja) * 2022-02-28 2024-10-25 一般社団法人 Unical ヒトによる経口摂取のためのカルシウム組成物
AU2023378960A1 (en) * 2022-11-08 2025-06-12 Amorphical Ltd. Methods for preparing amorphous calcium carbonate by fixation of carbon dioxide

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WO1998057656A1 (en) * 1997-06-19 1998-12-23 Allelix Biopharmaceuticals Inc. A combined pharmaceutical preparation comprising parathyroid hormone and a bone resorption inhibitor
CN101123945A (zh) * 2004-05-26 2008-02-13 尼吉夫研究及发展机构本-格里昂大学 含有稳定的无定形碳酸钙的可口服给药的组合物
CN101969962A (zh) * 2007-10-22 2011-02-09 艾玛菲克有限公司 包含磷酸化氨基酸、合成的磷酸化肽和胃石蛋白的稳定的无定形碳酸钙

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DE3875867T2 (de) 1987-08-28 1993-04-01 Norwich Eaton Pharma Kalziumzusaetze.
GB2217988B (en) 1988-04-11 1992-04-01 Gould Leonard W Regimen for increasing bone density in humans
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Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO1998057656A1 (en) * 1997-06-19 1998-12-23 Allelix Biopharmaceuticals Inc. A combined pharmaceutical preparation comprising parathyroid hormone and a bone resorption inhibitor
CN101123945A (zh) * 2004-05-26 2008-02-13 尼吉夫研究及发展机构本-格里昂大学 含有稳定的无定形碳酸钙的可口服给药的组合物
CN101969962A (zh) * 2007-10-22 2011-02-09 艾玛菲克有限公司 包含磷酸化氨基酸、合成的磷酸化肽和胃石蛋白的稳定的无定形碳酸钙

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Publication number Publication date
AU2012354056B2 (en) 2017-10-05
WO2013088440A1 (en) 2013-06-20
US20150056306A1 (en) 2015-02-26
ES2831699T3 (es) 2021-06-09
CA3056570A1 (en) 2013-06-20
CN104114179A (zh) 2014-10-22
AU2017279824A1 (en) 2018-01-25
EP2790710B1 (en) 2020-08-26
IL233107B (en) 2020-06-30
IL274755A (en) 2020-07-30
AU2012354056A1 (en) 2014-07-10
JP2015500333A (ja) 2015-01-05
JP2019214631A (ja) 2019-12-19
AU2020200704A1 (en) 2020-02-20
CA2859122A1 (en) 2013-06-20
DK2790710T3 (da) 2020-11-30
WO2013088440A8 (en) 2013-08-01
IL274755B (en) 2021-04-29
CA2859122C (en) 2019-11-05
US10064890B2 (en) 2018-09-04
JP2018138591A (ja) 2018-09-06
EP2790710A1 (en) 2014-10-22
US20190022133A1 (en) 2019-01-24
US10688124B2 (en) 2020-06-23
EP2790710A4 (en) 2015-11-11
IL233107A0 (en) 2014-07-31
CA3056570C (en) 2022-04-19
AU2012354056A8 (en) 2017-10-12

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