CA2859122C - Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders - Google Patents
Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders Download PDFInfo
- Publication number
- CA2859122C CA2859122C CA2859122A CA2859122A CA2859122C CA 2859122 C CA2859122 C CA 2859122C CA 2859122 A CA2859122 A CA 2859122A CA 2859122 A CA2859122 A CA 2859122A CA 2859122 C CA2859122 C CA 2859122C
- Authority
- CA
- Canada
- Prior art keywords
- calcium
- acc
- composition
- subjects
- bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/612—Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA3056570A CA3056570C (en) | 2011-12-13 | 2012-12-13 | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161569805P | 2011-12-13 | 2011-12-13 | |
| US61/569,805 | 2011-12-13 | ||
| US201261680721P | 2012-08-08 | 2012-08-08 | |
| US61/680,721 | 2012-08-08 | ||
| PCT/IL2012/050521 WO2013088440A1 (en) | 2011-12-13 | 2012-12-13 | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3056570A Division CA3056570C (en) | 2011-12-13 | 2012-12-13 | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2859122A1 CA2859122A1 (en) | 2013-06-20 |
| CA2859122C true CA2859122C (en) | 2019-11-05 |
Family
ID=48611949
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2859122A Active CA2859122C (en) | 2011-12-13 | 2012-12-13 | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
| CA3056570A Active CA3056570C (en) | 2011-12-13 | 2012-12-13 | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3056570A Active CA3056570C (en) | 2011-12-13 | 2012-12-13 | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10064890B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2790710B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2015500333A (cg-RX-API-DMAC7.html) |
| CN (2) | CN109568338A (cg-RX-API-DMAC7.html) |
| AU (3) | AU2012354056B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2859122C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2790710T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2831699T3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL233107B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013088440A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016507553A (ja) * | 2013-02-11 | 2016-03-10 | アモーフィカル リミテッド． | 骨成長を促進する非晶質炭酸カルシウム |
| EP3174409A4 (en) | 2014-07-31 | 2018-01-17 | Amorphical Ltd. | Encapsulated amorphous calcium carbonate compositions |
| US12121538B2 (en) | 2015-06-04 | 2024-10-22 | Amorphical Ltd. | Compositions of amorphous calcium carbonate for inhalation, sublingual or buccal administration |
| HK1253702A1 (zh) * | 2015-06-04 | 2019-06-28 | 艾玛菲克有限公司 | 用聚磷酸/聚磷酸酯/聚磷酸盐或双膦酸/双膦酸酯/双膦酸盐稳定的无定形碳酸钙 |
| JP2017032550A (ja) * | 2015-07-30 | 2017-02-09 | 大塚製薬株式会社 | 胃粘膜萎縮の有無を判定する方法 |
| ES3052833T3 (en) | 2016-01-18 | 2026-01-15 | Amorphical Ltd | Stabilized amorphous calcium carbonate as a supplement for cell culture media |
| US20230365935A1 (en) * | 2016-01-18 | 2023-11-16 | Amorphical Ltd. | Stabilized amorphous calcium carbonate as a supplement for cell culture media |
| JP6873389B2 (ja) | 2016-01-18 | 2021-05-19 | アモーフィカル リミテッド． | 神経学的、筋肉、および不妊の疾患または症状の治療のための安定化無定形炭酸カルシウム |
| JP6872680B2 (ja) * | 2016-03-22 | 2021-05-19 | 国立大学法人 宮崎大学 | カルシウム吸収促進剤 |
| JP7152785B2 (ja) * | 2016-10-25 | 2022-10-13 | アモーフィカル リミテッド． | 白血病治療のための非晶質炭酸カルシウム |
| CN110123836A (zh) * | 2019-05-20 | 2019-08-16 | 昆明朗盛生物科技有限公司 | 钙锌维生素d泛酸片的应用 |
| IL289237B2 (en) | 2019-07-23 | 2026-03-01 | Amorphical Ltd | Amorphous calcium carbonate for improving athletic performance |
| WO2021181372A1 (en) * | 2020-03-11 | 2021-09-16 | Amorphical Ltd. | Amorphous calcium carbonate for treatment of acidosis |
| US20230223125A1 (en) * | 2020-05-04 | 2023-07-13 | University Of Louisville Research Foundation, Inc. | Artificial intelligence-based systems and methods for dosing of pharmacologic agents |
| CN121731510A (zh) * | 2020-09-15 | 2026-03-27 | 昂科因凡特解决方案公司 | 尺寸可控的放射性标记粒子 |
| JP7573310B2 (ja) * | 2022-02-28 | 2024-10-25 | 一般社団法人 Unical | ヒトによる経口摂取のためのカルシウム組成物 |
| AU2023378960A1 (en) * | 2022-11-08 | 2025-06-12 | Amorphical Ltd. | Methods for preparing amorphous calcium carbonate by fixation of carbon dioxide |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3875867T2 (de) | 1987-08-28 | 1993-04-01 | Norwich Eaton Pharma | Kalziumzusaetze. |
| GB2217988B (en) | 1988-04-11 | 1992-04-01 | Gould Leonard W | Regimen for increasing bone density in humans |
| WO1997024069A1 (en) | 1995-12-26 | 1997-07-10 | Holomed Aps | A method and system for generating an x-ray image |
| JPH10236957A (ja) | 1997-02-24 | 1998-09-08 | Bankaku Souhonpo:Kk | 骨粗鬆症の改善剤 |
| SE9702401D0 (sv) * | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
| JP2003292453A (ja) * | 2002-04-02 | 2003-10-15 | Asahi Kasei Corp | 骨疾患治療用医薬複合剤 |
| US7267832B2 (en) * | 2004-02-18 | 2007-09-11 | Kraft Foods Holdings, Inc. | Amorphous water-soluble calcium citrate salts and method of making and using same |
| CA2567972C (en) | 2004-05-26 | 2015-07-28 | Ben-Gurion University Of The Negev Research And Development Authority | Orally-administrable compositions comprising stable amorphous calcium carbonate |
| US20070041506A1 (en) | 2005-08-22 | 2007-02-22 | Michelle Bottino | Digital sensor holder |
| GB0522045D0 (en) | 2005-10-28 | 2005-12-07 | Novartis Ag | Pharmaceutical compositions |
| IL178495A (en) * | 2006-10-05 | 2014-12-31 | Univ Ben Gurion | Use of cancerous gastric components or artificial calcium containing carbonate, chitin and polypeptide preparations to treat calcium metabolism-related or calcium-signaling conditions |
| PL2211873T3 (pl) * | 2007-10-22 | 2013-01-31 | Amorphical Ltd | Stabilny amorficzny węglan wapnia wchodzący w skład fosforylowanych aminokwasów |
| WO2009087553A1 (en) | 2008-01-02 | 2009-07-16 | Aurobindo Pharma Limited | Kits for administering bisphosphonates |
| CN101314031A (zh) | 2008-07-14 | 2008-12-03 | 王冰 | 一种改善骨营养的制剂 |
| EP2334292B1 (en) * | 2008-10-17 | 2019-05-08 | Fresenius Medical Care Holdings, Inc. | Method of determining a phosphorus binder dosage for a dialysis patient |
| CN102085356B (zh) | 2010-12-28 | 2013-02-27 | 北京同仁堂健康药业股份有限公司 | 一种用于增加骨密度的组合物及其制备方法 |
-
2012
- 2012-12-13 EP EP12857932.3A patent/EP2790710B1/en active Active
- 2012-12-13 CN CN201910013584.9A patent/CN109568338A/zh active Pending
- 2012-12-13 CA CA2859122A patent/CA2859122C/en active Active
- 2012-12-13 US US14/364,992 patent/US10064890B2/en active Active
- 2012-12-13 AU AU2012354056A patent/AU2012354056B2/en active Active
- 2012-12-13 CN CN201280069595.5A patent/CN104114179A/zh active Pending
- 2012-12-13 DK DK12857932.3T patent/DK2790710T3/da active
- 2012-12-13 WO PCT/IL2012/050521 patent/WO2013088440A1/en not_active Ceased
- 2012-12-13 JP JP2014546729A patent/JP2015500333A/ja active Pending
- 2012-12-13 CA CA3056570A patent/CA3056570C/en active Active
- 2012-12-13 ES ES12857932T patent/ES2831699T3/es active Active
-
2014
- 2014-06-12 IL IL233107A patent/IL233107B/en active IP Right Grant
-
2017
- 2017-12-28 AU AU2017279824A patent/AU2017279824A1/en not_active Abandoned
-
2018
- 2018-05-08 JP JP2018089672A patent/JP2018138591A/ja active Pending
- 2018-07-31 US US16/050,651 patent/US10688124B2/en active Active
-
2019
- 2019-10-01 JP JP2019181138A patent/JP2019214631A/ja active Pending
-
2020
- 2020-01-31 AU AU2020200704A patent/AU2020200704A1/en not_active Abandoned
- 2020-05-18 IL IL274755A patent/IL274755B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012354056B2 (en) | 2017-10-05 |
| WO2013088440A1 (en) | 2013-06-20 |
| US20150056306A1 (en) | 2015-02-26 |
| ES2831699T3 (es) | 2021-06-09 |
| CA3056570A1 (en) | 2013-06-20 |
| CN104114179A (zh) | 2014-10-22 |
| AU2017279824A1 (en) | 2018-01-25 |
| EP2790710B1 (en) | 2020-08-26 |
| IL233107B (en) | 2020-06-30 |
| IL274755A (en) | 2020-07-30 |
| AU2012354056A1 (en) | 2014-07-10 |
| JP2015500333A (ja) | 2015-01-05 |
| JP2019214631A (ja) | 2019-12-19 |
| AU2020200704A1 (en) | 2020-02-20 |
| CA2859122A1 (en) | 2013-06-20 |
| DK2790710T3 (da) | 2020-11-30 |
| WO2013088440A8 (en) | 2013-08-01 |
| IL274755B (en) | 2021-04-29 |
| US10064890B2 (en) | 2018-09-04 |
| JP2018138591A (ja) | 2018-09-06 |
| CN109568338A (zh) | 2019-04-05 |
| EP2790710A1 (en) | 2014-10-22 |
| US20190022133A1 (en) | 2019-01-24 |
| US10688124B2 (en) | 2020-06-23 |
| EP2790710A4 (en) | 2015-11-11 |
| IL233107A0 (en) | 2014-07-31 |
| CA3056570C (en) | 2022-04-19 |
| AU2012354056A8 (en) | 2017-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20171213 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - STANDARD Year of fee payment: 12 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20241204 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20241204 Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20241204 |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 13TH ANNIV.) - STANDARD Year of fee payment: 13 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20251201 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20251201 |