CN109567934B - Double-optical-fiber laser treatment system - Google Patents
Double-optical-fiber laser treatment system Download PDFInfo
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- CN109567934B CN109567934B CN201811494995.6A CN201811494995A CN109567934B CN 109567934 B CN109567934 B CN 109567934B CN 201811494995 A CN201811494995 A CN 201811494995A CN 109567934 B CN109567934 B CN 109567934B
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
Abstract
The invention provides a double-fiber laser treatment system, which is characterized in that two laser transmission channels are arranged, wherein a photo-thermal material is arranged on the end face of a contact type optical fiber, the high-efficiency photo-thermal conversion of the photo-thermal material is utilized to improve the heat production capacity of a probe and improve the temperature of the tail end of the optical fiber, the optical fiber is directly contacted with a tissue in the operation process and then is matched with laser emitted by the non-contact optical fiber, so that high temperature and laser simultaneously act on the tissue, the operation efficiency is greatly improved, the required laser power is greatly reduced compared with that of the traditional optical fiber non-contact method, and the problem of the. The laser cutter head adopts a replaceable structure, and after the laser cutter head is used for one time, the laser cutter head can be replaced without replacing the laser conduction optical fiber, so that the consumption cost is greatly saved.
Description
Technical Field
The invention relates to the field of medical equipment, in particular to a double-fiber laser treatment system.
Background
Lasers have gained considerable attention in the field of surgery because of their very good cutting power, good coagulation and little thermal damage. The high-energy pulse laser generated by the laser is transmitted out through the optical fiber, the optical fiber enters the human body through the endoscope, the energy of the laser is transmitted into the part needing laser treatment, and effective and safe treatment is carried out on a patient by utilizing the characteristics of high energy, collimation, short action time, small heat affected area and the like of the laser. The interaction of laser light on biological tissue is the physical basis of medical applications, and the thermal effect of laser light is one of the most widely used and earliest recognized effects of laser tissue in medicine. The laser light is incident on the tissue of the living body, and the absorbed light energy is converted into heat in the light penetration depth range. When the heating rate (the heat energy comes from laser irradiation, and is related to two factors of laser intensity and tissue absorption coefficient) is far higher than the rate of heat required for vaporizing the tissue, the tissue is vaporized and ablated quickly.
The thulium-doped fiber laser can output laser with the wavelength of 1.65-2.1 um, is the widest of all rare earth ions, and has the advantages of simple structure, high efficiency, good heat dissipation characteristic, narrow line width, high quality of output laser beams and the like compared with a solid laser, so that the thulium fiber laser with high peak power pulse output is widely researched in recent years. However, the thulium-doped fiber laser with the wavelength of about 2 μm needs larger pulse energy for cutting and gasifying the tissues, and the laser power is mainly provided by the thulium-doped fiber core. However, with the significant enhancement of the optical power density in the thulium-doped gain fiber, a severe thermal effect occurs, which causes phenomena such as thermal birefringence, phase distortion, thermal focusing, thermal lens, etc., which seriously affects the output power and beam quality of the laser, and becomes a fatal factor for limiting the performance improvement of the laser.
Chinese patent publication No. CN104638506A discloses a 1.9 micron high-power prostate laser therapeutic apparatus, which can perform compensation in different ways for different operating powers, and solve the problems of efficiency reduction and light beam quality deterioration of thulium-doped fiber laser in order to increase power. But this solution still does not solve the problem of thermal effects of the fiber.
CN107412957A discloses a photothermal therapy probe based on photothermal nano material, which comprises a cylindrical shell with one end closed, and photothermal nano material filled in the closed end inside the shell, and kills tumor and other pathological tissue cells by implementing high temperature. However, this solution only uses high temperature to perform the treatment, and it encloses the nano-material in the housing, which is complicated in structure and inefficient in heat generation.
Disclosure of Invention
In order to solve the problems, the invention provides a dual-fiber laser treatment system, two laser transmission channels are arranged, wherein a photo-thermal material is arranged on the end face of a contact type optical fiber, the heat generating capacity of a probe is improved by utilizing the efficient photo-thermal conversion of the photo-thermal material, the temperature of the tail end of the optical fiber is improved, the optical fiber is directly contacted with a tissue in the operation process and then is matched with laser emitted by the non-contact optical fiber, so that high temperature and laser simultaneously act on the tissue, the operation efficiency is greatly improved, the required laser power is greatly reduced compared with that of a traditional optical fiber non-contact method, and the problem of the thermal effect of the. The laser cutter head adopts a replaceable structure, and after the laser cutter head is used for one time, the laser cutter head can be replaced without replacing the laser conduction optical fiber, so that the consumption cost is greatly saved.
The technical scheme of the invention is as follows:
the utility model provides a two optical fiber laser treatment systems, the system includes laser light source and laser treatment device, the laser treatment device is including the insert tube, be provided with working channel in the insert tube, be provided with contact laser transmission optic fibre and non-contact laser transmission optic fibre in the working channel, wherein contact laser transmission optic fibre includes transmission part and light-emitting part, light-emitting part with transmission part detachable connects, just be formed with the optothermal material on the terminal surface of light-emitting part, contact laser transmission optic fibre can be along axial displacement in working channel, laser light source is including mixing thulium light source and infrared light source.
The photo-thermal material covers the end face of the optical fiber, and the high-efficiency photo-thermal conversion of the photo-thermal material improves the heat generating capacity of the probe and the temperature of the optical fiber. The contact type laser optical fiber with the end surface provided with the photo-thermal material transmits infrared light, and the non-contact type laser transmission optical fiber transmits output laser from the thulium-doped gain optical fiber.
During operation, the contact type laser transmission optical fiber can extend out of the working channel and directly contact with tissues.
Preferably, the contact type laser transmission fiber and the non-contact type laser transmission fiber are located in different working channels, and the tail end of the working channel where the non-contact type laser transmission fiber is located is provided with the transparent light exit window, so that the fibers cannot be polluted in the using process and can be reused.
The photo-thermal material can be formed on the surface of the optical fiber by any one of coating, vapor deposition, magnetron sputtering, evaporation and welding. The fusion bonding is performed under a protective atmosphere using an atmosphere composed of He gas, which is effective in preventing oxidation of the material at high temperatures.
The photothermal material may be one or more of a metal photothermal material, diamond, or a semiconductor photothermal material.
Preferably, the photothermal material is a nanomaterial.
The photo-thermal nano material can be one or more of metal photo-thermal nano material, nano diamond or semiconductor nano photo-thermal material.
The metal photo-thermal nano material can be one or more of gold, platinum and palladium nano materials.
The semiconductor nano material can be one or more of copper sulfide, molybdenum sulfide, bismuth sulfide, antimony sulfide, gold sulfide copper selenide, molybdenum selenide, bismuth selenide, antimony selenide or gold selenide.
The density and thickness of the photothermal material are set according to the laser power and clinical temperature requirements. For example, the thickness may be 100 micrometers or less, further, 50 micrometers or less, further, 1 micrometer or less, further, 500 nanometers or less and not less than 1 nanometer.
The laser light source comprises a pumping source, a beam splitter and a resonant cavity, the resonant cavity comprises two cavity mirrors and a doped gain fiber, the two cavity mirrors are semi-transparent and semi-reflective mirrors, the first cavity mirror transmits pumping light and reflects signal light generated by the gain fiber, the second cavity mirror transmits the signal light generated by the gain fiber and reflects the pumping light, and the beam splitter can control the amount of the pumping light entering the resonant cavity.
The pumping source adopts near infrared semiconductor laser pumping.
The beam splitter structure includes three blades, one of which is a half-silvered mirror so that a portion of light that is incident at a 45-degree angle and is not absorbed by the coating (the amount of transmitted light can be controlled by controlling the thickness of the deposit or the coating area) is transmitted and the remaining portion is reflected, one of which is a total reflection mirror and the other of which is a total transmission mirror. The beam splitter can rotate around the axis as required to control any one of the three blades to be positioned in the light path. When the photodynamic therapy is carried out, the total reflection mirror is positioned in the optical path to reflect all the pump light, so that the optical fiber outputs near infrared light for the photodynamic therapy. When laser therapy is carried out, the full-projection lens is positioned in the light path, all the pump light is transmitted, the pump light enters the resonant cavity to generate output laser, and the optical fiber outputs 2um high-energy pulse laser for laser therapy. When the photodynamic therapy and the laser therapy are used in a matched mode, the half-silvered mirror is located in the light path, part of pump light is reflected, and part of pump light is transmitted.
Preferably, half silvered mirror can be changed as required, adjusts and controls the proportion of output near-infrared and 2um high energy pulse laser through using the half silvered mirror of different transmission ratios.
The half-silvered mirror may be produced by sputtering a metal coating onto a sheet of glass or plastic, forming a discontinuous coating or by removing small areas of a continuous coating by chemical or mechanical action.
The transmission part and the light-emitting part of the contact type optical fiber are detachably connected through threaded connection or clamping connection. The light exit portion is provided with a sheath covering the working channel. The sheath covers the working channel, can prevent that steam from getting into the working channel, prevents the pollution to the working channel.
The sheath is made of elastic materials, and preferably rubber materials.
The edge of the working channel protrudes out of the plane of the end of the endoscope by a certain length and is used for fixing the sheath.
Optionally, the working channel rim is formed with an annular recess for fixation of the sheath.
The contact type optical fiber can move in the working channel along the axial direction, a bayonet matched with the contact type optical fiber is arranged at the front end of the working channel, the bayonet comprises an elastic brake pad for sealing the bayonet, a switch for controlling the brake pad is arranged outside the bayonet, the brake pad is opened, the transmission part can extend out of the bayonet and is connected with the cutter head, after treatment is finished, the cutter head and the sheath are cleaned, the connection between the light output part and the transmission part is released, the transmission part is retracted into the bayonet, the brake pad automatically rebounds to seal the bayonet, and then the fixed connection between the sheath and the working channel is released, so that after an operation, only the outside of the endoscope is cleaned and disinfected, and the working channel of the endoscope is not required to be cleaned and disinfected.
The shape of brake lining can set up as required, can be two semicircular brake linings, also can be a plurality of triangle blade.
Further, the apparatus includes a temperature sensor disposed near the fiber tip to monitor the temperature.
Further, the device comprises a cooling and cleaning channel for spraying liquid to the target part to clean and cool the target part.
Compared with the prior art, the invention has the following beneficial effects:
1. the probe intervenes in a focus tissue part through minimally invasive, the temperature of the optical fiber is increased through a high-efficiency photothermal conversion mechanism of photothermal materials on the end face of the contact type optical fiber, the optical fiber contact type and non-contact type laser combined surgical operation is carried out, high temperature and laser simultaneously act on the tissue, so that the operation efficiency is greatly improved, the laser operation has the characteristics of high energy, collimation, short action time and small heat affected zone, meanwhile, the required laser power is greatly reduced compared with that of the traditional optical fiber non-contact type method, and the heat effect problem of the optical fiber is reduced.
2. The optical fiber is directly contacted with the photo-thermal material, the structure is simple, and in addition, the loss of laser energy is greatly reduced.
3. The system complexity is low. Because the power of the product is low, and the temperature of other parts except the pinhead can not rise during working, a water cooling system is not needed, and the complexity of the system is greatly reduced.
4. The laser cutter head adopts a replaceable structure, and after the laser cutter head is used for one time, the laser cutter head can be replaced without replacing the laser conduction optical fiber, so that the consumption cost is greatly saved.
Drawings
Fig. 1 is a schematic structural diagram of a laser treatment device.
Fig. 2 is a schematic structural diagram of a laser light source.
Fig. 3 is a schematic view of the sheath structure.
In the figure, 1-non-contact laser transmission fiber, 2-contact laser transmission fiber, 3-photo-thermal material, 4-doped gain fiber, 5-second cavity mirror, 6-beam combiner.
Detailed Description
In order to make the objects, technical solutions and advantageous technical effects of the present invention clearer, the present invention is further described in detail with reference to the following embodiments. It should be understood that the embodiments described in this specification are only for explaining the present invention and are not to be limited thereto, and the specific parameter settings and the like of the embodiments can be selected according to the circumstances without substantially affecting the results.
Example 1
As shown in fig. 1, a two optic fibre laser therapy system, the system includes laser light source and laser therapy device, the laser therapy device is including the insert tube, be provided with working channel in the insert tube, be provided with contact laser transmission optic fibre 2 and non-contact laser transmission optic fibre 1 in the working channel, wherein contact laser transmission optic fibre 2 is including transmission part and light-emitting part, light-emitting part with transmission part detachable connects, just be formed with the optothermal material on the terminal surface of light-emitting part, and can follow axial displacement in working channel, laser light source is including thulium-doped light source and infrared light source.
The photo-thermal material 3 covers the end face of the optical fiber, and the high-efficiency photo-thermal conversion of the photo-thermal material improves the heat generating capacity of the probe and the temperature of the optical fiber. The contact type laser optical fiber 2 with the end surface provided with the photo-thermal material 3 transmits infrared light, and the non-contact type laser transmission optical fiber 1 transmits output laser from the thulium-doped gain optical fiber.
During operation, the contact type laser transmission optical fiber 2 can extend out of the working channel to directly contact with tissues.
The contact type laser transmission optical fiber 2 and the non-contact type laser transmission optical fiber 1 are positioned in different working channels, and the tail end of the working channel where the non-contact type laser transmission optical fiber 1 is positioned is provided with the transparent light exit window 9, so that the optical fibers cannot be polluted in the using process and can be reused.
The photo-thermal material 3 may be formed on the surface of the optical fiber by any one of coating, vapor deposition, magnetron sputtering, evaporation and fusion. The fusion bonding is performed under a protective atmosphere using an atmosphere composed of He gas, which is effective in preventing oxidation of the material at high temperatures.
The photothermal material may be one or more of a metallic photothermal material, diamond, or a semiconductor material.
The photo-thermal material is a nano material.
The photo-thermal nano material may be one or more of a metal photo-thermal nano material, a nano diamond or a semiconductor nano material.
The metal photo-thermal nano material can be one or more of gold, platinum and palladium nano materials.
The semiconductor nano material can be one or more of copper sulfide, molybdenum sulfide, bismuth sulfide, antimony sulfide, gold sulfide copper selenide, molybdenum selenide, bismuth selenide, antimony selenide or gold selenide.
The density and thickness of the photothermal material are set according to the laser power and clinical temperature requirements. For example, the thickness may be 100 micrometers or less, further, 50 micrometers or less, further, 1 micrometer or less, further, 500 nanometers or less and not less than 1 nanometer.
As shown in fig. 2, the laser light source includes a pumping source 4, a beam splitter 8 and a resonant cavity, the resonant cavity includes two cavity mirrors 5,7 and a doped gain fiber 6, both the two cavity mirrors 5,7 are semi-transparent semi-reflective mirrors, the first cavity mirror 5 transmits pumping light and reflects signal light generated by the gain fiber, the second cavity mirror 7 transmits signal light generated by the gain fiber and reflects the pumping light, and the beam splitter 8 can control the amount of pumping light entering the resonant cavity.
The pump source 4 adopts near infrared semiconductor laser pumping.
The beam splitter structure 8 comprises three blades, one of which is a half-silvered mirror so that the part of the light that is incident at a 45 degree angle and is not absorbed by the coating (the amount of transmitted light can be controlled by controlling the thickness of the deposit or the coating area) is transmitted and the rest is reflected, one of which is a total reflection mirror and the other of which is a total transmission mirror. The beam splitter can rotate around the axis as required to control any one of the three blades to be positioned in the light path. When the photodynamic therapy is carried out, the total reflection mirror is positioned in the optical path to reflect all the pump light, so that the optical fiber outputs near infrared light for the photodynamic therapy. When laser therapy is carried out, the full-projection lens is positioned in the light path, all the pump light is transmitted, the pump light enters the resonant cavity to generate output laser, and the optical fiber outputs 2um high-energy pulse laser for laser therapy. When the photodynamic therapy and the laser therapy are used in a matched mode, the half-silvered mirror is located in the light path, part of pump light is reflected, and part of pump light is transmitted.
The semi-silvered mirror can be replaced as required, and the proportion of outputting near infrared and 2um high-energy pulse laser is regulated and controlled by using the semi-silvered mirror with different transmission proportions.
The half-silvered mirror may be produced by sputtering a metal coating onto a sheet of glass or plastic, forming a discontinuous coating or by removing small areas of a continuous coating by chemical or mechanical action.
The transmission part and the light-emitting part of the contact type optical fiber 2 are detachably connected through threaded connection or clamping connection. The light exit portion is provided with a sheath covering the working channel as shown in figure 3. The sheath covers the working channel, can prevent that steam from getting into the working channel, prevents the pollution to the working channel.
The sheath is made of elastic materials, and preferably rubber materials.
The edge of the working channel protrudes out of the plane of the end of the endoscope by a certain length and is used for fixing the sheath.
The edge of the working channel is formed with an annular recess for fixing the sheath.
The contact type optical fiber 2 can move in the working channel along the axial direction, a bayonet matched with the contact type optical fiber is arranged at the front end of the working channel, the bayonet comprises an elastic brake pad for sealing the bayonet, a switch for controlling the brake pad is arranged outside the bayonet, the brake pad is opened, the transmission part can extend out of the bayonet and is connected with the cutter head, after treatment is finished, the cutter head and the sheath are cleaned, the connection between the light output part and the transmission part is released, the transmission part is retracted into the bayonet, the brake pad automatically rebounds to seal the bayonet, and then the fixed connection between the sheath and the working channel is released, so that after an operation, only the outside of the endoscope is cleaned and disinfected, and the working channel of the endoscope is not required to be cleaned and disinfected.
The shape of brake lining can set up as required, can be two semicircular brake linings, also can be a plurality of triangle blade.
The apparatus includes a temperature sensor disposed near the end of the optical fiber to monitor temperature.
The device comprises a cooling and cleaning channel for spraying liquid to a target part to clean and cool the target part.
Although the preferred embodiments of the present patent have been described in detail, the present patent is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present patent within the knowledge of those skilled in the art.
Claims (9)
1. The utility model provides a two optical fiber laser treatment system, its characterized in that, the system includes laser light source and laser treatment device, laser treatment device includes the insert tube, be provided with working channel in the insert tube, be provided with contact laser transmission optic fibre and non-contact laser transmission optic fibre in the working channel, wherein contact laser transmission optic fibre includes transmission part and light-emitting part, light-emitting part with transmission part detachable connects, just be formed with the optothermal material on the terminal surface of light-emitting part, contact laser transmission optic fibre can be along axial displacement in working channel, laser light source includes thulium-doped light source and infrared light source; the laser light source comprises a pumping source, a beam splitter and a resonant cavity, the resonant cavity comprises two cavity mirrors and a doped gain fiber, the two cavity mirrors are semi-transparent and semi-reflective mirrors, the first cavity mirror transmits pumping light and reflects signal light generated by the gain fiber, the second cavity mirror transmits the signal light generated by the gain fiber and reflects the pumping light, and the beam splitter can control the amount of the pumping light entering the resonant cavity.
2. The laser therapy system according to claim 1, wherein the end face has a contact laser fiber of a photo-thermal material to transmit infrared light and the non-contact laser fiber transmits output laser light from a thulium doped gain fiber.
3. The laser therapy system according to claim 1, wherein the contact laser delivery fiber and the non-contact laser delivery fiber are located in different working channels, and the non-contact laser delivery fiber is located at the end of the working channel with a transparent light exit window.
4. The laser therapy system according to claim 1, wherein the photothermal material is formed on the surface of the optical fiber by any one of coating, vapor deposition, magnetron sputtering, evaporation, and fusion.
5. The laser therapy system according to claim 1, wherein the photothermal material is one or more of a metallic photothermal nanomaterial, a nanodiamond, or a semiconductor photothermal material.
6. The laser therapy system according to claim 1, wherein the pump source employs near infrared semiconductor laser pumping.
7. The laser therapy system according to claim 1, wherein the transmission portion of the contact optical fiber and the light emitting portion are detachably connected by a screw connection or a snap connection.
8. The laser therapy system according to claim 1, wherein the light exit portion is provided with a sheath covering the working channel.
9. The laser therapy system according to claim 8, wherein the sheath is made of an elastic material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811494995.6A CN109567934B (en) | 2018-12-07 | 2018-12-07 | Double-optical-fiber laser treatment system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811494995.6A CN109567934B (en) | 2018-12-07 | 2018-12-07 | Double-optical-fiber laser treatment system |
Publications (2)
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| CN102688095B (en) * | 2012-06-15 | 2014-08-27 | 上海安通医疗科技有限公司 | Laser ablation conduit for renal artery |
| US20170050043A1 (en) * | 2014-04-18 | 2017-02-23 | Yukyong National University Industry-University Cooperation Foundation | Probe comprising optically diffusing fiber, method for manufacturing same and applications thereof |
| CN107412957B (en) * | 2017-07-12 | 2019-09-10 | 华东师范大学 | A kind of photo-thermal therapy probe based on photo-thermal nano material |
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