CN109452969B - A kind of laser surgey optical fiber of the flexible end with optothermal material - Google Patents

A kind of laser surgey optical fiber of the flexible end with optothermal material Download PDF

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Publication number
CN109452969B
CN109452969B CN201811494964.0A CN201811494964A CN109452969B CN 109452969 B CN109452969 B CN 109452969B CN 201811494964 A CN201811494964 A CN 201811494964A CN 109452969 B CN109452969 B CN 109452969B
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optical fiber
laser
optothermal material
laser surgey
optothermal
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CN109452969A (en
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梁瑶
詹凯
傅喜泉
王洪波
潘友华
李泊文
梁雷
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China Polytron Technologies Inc
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China Polytron Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02Optical fibres with cladding with or without a coating
    • G02B6/036Optical fibres with cladding with or without a coating core or cladding comprising multiple layers
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/44Mechanical structures for providing tensile strength and external protection for fibres, e.g. optical transmission cables
    • G02B6/4401Optical cables
    • G02B6/4429Means specially adapted for strengthening or protecting the cables
    • G02B6/443Protective covering
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00595Cauterization
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2205Characteristics of fibres

Abstract

The present invention provides a kind of laser surgey optical fiber of the flexible end with optothermal material, by the way that optothermal material is arranged in fiber end face, the Thermogenesis of probe is improved using the efficient photothermal conversion of optothermal material, improve fiber optic temperature, optical Fiber Contact surgical operation is carried out again, the high temperature and laser of fiber tip act on tissue simultaneously and procedure efficiency are greatly improved, and required laser power is many compared to the decline of traditional fiber non-contact method, reduce the generation of the fuel factor problem of optical fiber.When being treated, cutter head can stretch out service aisle and energy free bend, adjust the angle, using flexible expands working range, can not be limited by endoscope diameter size, it can be applicable in narrow positions, may be implemented 360 degree without dead angle working range by the cooperation with laser probe.

Description

A kind of laser surgey optical fiber of the flexible end with optothermal material
Technical field
The present invention relates to laser therapy fields, and in particular to a kind of laser surgey of the flexible end with optothermal material Optical fiber.
Background technique
Laser is because of extraordinary cutting power, good coagulating effectiveness and lesser thermal damage, in surgical field It gets the attention.The high energy pulse laser that laser generates, is passed out by optical fiber, and optical fiber is entered by endoscope again Human body, by the incoming position for needing laser therapy of the energy of laser, using the high energy, collimation, action time of laser it is short and The features such as heat-affected zone is small carries out treatment effectively and safely for patient.Exportable 1.65~the 2.1um of thulium-doped fiber laser The laser of wavelength, be it is widest in all rare earth ions, for opposite solid state laser, have structure simple, high-efficient, scattered The advantages that thermal characteristics is good, narrow linewidth, high quality for outputting laser beam, thus the thulium optical fiber laser of high peak power pulse output Extensive research had been obtained in recent years.
Laser is the physical basis of medical application to the interaction of bio-tissue, and the fuel factor of laser is medically to make With one of the laser tissue effect being most recognized extensively and earliest.Laser light incident bio-tissue, in light penetration depth In range, absorbed luminous energy is converted into heat.When (thermal energy comes from laser irradiation to heating speed, inhales with laser intensity and tissue Receive two factors of coefficient in relation to) significantly larger than evaporate tissue institute calorific requirement speed, then tissue by vaporization quickly.Mix thulium light The laser of the exportable 1.65~2.1um wavelength of fibre laser, be it is widest in all rare earth ions, with respect to solid state laser Speech has many advantages, such as that structure is simple, high-efficient, heat dissipation characteristics are good, narrow linewidth, quality for outputting laser beam are high, thus peak value The thulium optical fiber laser of power pulse output had obtained extensive research in recent years.But the thulium-doped fiber laser pair near 2 μm It organizes the biggish pulse energy of operations needs such as cut, gasified, laser power is mainly provided by the fibre core for mixing thulium.But with Mix the significant reinforcement of optical power density in thulium gain fibre, it may appear that serious fuel factor causes thermally induced birefringence, phase abnormal Phenomena such as change, hot focus, thermal lens, seriously affects the output power and beam quality of laser, becomes limitation laser performance and mentions A high lethal factor.
The Chinese invention patent of Publication No. CN104638506A discloses 1.9 microns of high-power prostate laser of one kind and controls Instrument is treated, the compensation of different modes can be carried out for different operation power, solves thulium-doped fiber laser to increase power And there is the problems such as efficiency decline and beam quality variation.But this scheme still can not solve the problems, such as the fuel factor of optical fiber.
CN107412957A discloses a kind of photo-thermal therapy probe based on photo-thermal nano material comprising closed at one end Cylinder-like shell, the photo-thermal nano material for being filled in interior of shell closed end kill tumour and other diseases by implementing high temperature Become histocyte.But this scheme is implemented to treat only with high temperature, and it closes nano material inside the shell, knot Structure is complicated, heat production low efficiency.
Summary of the invention
To solve the above problems, the present invention provides a kind of laser surgey optical fiber of the flexible end with optothermal material, By the way that optothermal material is arranged in fiber end face, the Thermogenesis of probe is improved using the efficient photothermal conversion of optothermal material, is improved Fiber optic temperature, then optical Fiber Contact surgical operation is carried out, the high temperature and laser of fiber tip act on tissue simultaneously and to perform the operation Efficiency greatly improves, and required laser power is many compared to the decline of traditional fiber non-contact method, reduces the thermal effect of optical fiber Answer the generation of problem.When being treated, cutter head can stretch out service aisle and energy free bend, adjust the angle, using flexible, expand Big working range, can not be limited by endoscope diameter size, can be applicable in narrow positions, pass through the cooperation with laser probe 360 degree be may be implemented without dead angle working range.
Technical solution of the present invention is as follows:
A kind of laser surgey optical fiber of the flexible end with optothermal material, the operation optical fiber front end are provided with fixation Portion is fixed with control line on the fixed part, and the control line can control the operation fibre-optical bending, the operation optical fiber Optothermal material, the area of the optothermal material covering fiber end face 5%~60% are formed in distal end faces.
The operation optical fiber can be used cooperatively with endoscope, and the service aisle of endoscope can be inserted in the operation optical fiber In, and can be moved axially in the service aisle.
The optothermal material covering part fiber end face, in this way, the efficient photothermal conversion of optothermal material improves the production of probe Thermal energy power improves fiber optic temperature, but does not influence the output of laser.The covering shape of the optothermal material can be according to practical need It is arranged, for example can is shapes such as circle, annulus, spot distribution, threadiness, radial or combinations thereof.
The operation optical fiber includes operation portion, and the operation portion is provided with the component for pulling the control line, is used Person is by pulling the control line, to control the bending of the operation optical fiber.
The operation optical fiber includes fibre core and the covering for being sheathed on fibre core surface, and the covering includes inner cladding and outsourcing Layer, doped aluminium or germanium oxide in the inner cladding improve the refractive index of inner cladding, reduce the numerical aperture of fibre core, be arranged Surrounding layer on the inner cladding surface includes silica.
The operation optical fiber includes sheath made of resin, and the sheath is arranged after surrounding layer, the control line It is arranged in the resin sheath.
The case where control line can be two or four, two, two control lines are oppositely arranged, four feelings Condition, four control lines are circumferentially uniformly distributed.
The optothermal material can pass through any one method shape in coating, vapor deposition, magnetron sputtering, vapor deposition, welding The surface of optical fiber described in Cheng Yu.Welding carries out under protective atmosphere, using the atmosphere by He gas composition, can effectively prevent in this way The only oxidation of material under high temperature.
It is preferred that the area control of the optothermal material covering fiber end face is especially preferred 30%~50% with 35%.This Sample, the outgoing of influence laser that will not be too many, can improve the Thermogenesis of probe, improve fiber optic temperature, but do not influence to swash The output of light.
The optothermal material can be one of metal optothermal material, diamond or semiconductor light hot material or a variety of.
The photo-thermal nano material can be metal photo-thermal nano material, Nano diamond or semiconductor photo-thermal nano material One of or it is a variety of.
The metal photo-thermal nano material can be one of gold, platinum, nanometer Pd material or a variety of.
The semiconductor photo-thermal nano material can for copper sulfide, molybdenum sulfide, bismuth sulfide, antimony trisulfide, aurosulfo copper selenide, One of selenizing molybdenum, bismuth selenide, antimony selenide or Auric selenide are a variety of.
Compared with prior art, the beneficial effects of the present invention are:
Operation optical fiber can freely stretch out service aisle, and energy free bend, expand working range, can not be peeped by interior The limitation of mirror diameter dimension can be applicable in narrow positions, may be implemented 360 degree without dead angle work model by the cooperation with laser probe It encloses.
Probe gets involved in lesion tissue position by minimally invasive, then passes through the efficient photothermal conversion mechanism of optothermal material, passes through Fiber optic temperature is improved, then carries out optical Fiber Contact surgical operation, the high temperature and laser of fiber tip act on tissue simultaneously and makes Procedure efficiency greatly improves, and has laser surgey high energy, collimation, the feature that action time is short and heat-affected zone is small, simultaneously Required laser power is many compared to the decline of traditional fiber non-contact method, reduces the generation of the fuel factor problem of optical fiber.
1, optical fiber is directly contacted with optothermal material in the present invention, and structure is simple, in addition also greatly reduces laser energy Loss.
Detailed description of the invention
Fig. 1 is laser surgey optical fiber front-end architecture schematic diagram of the present invention;
Fig. 2 is laser surgey optical fiber general structure schematic diagram of the present invention;
In figure, 1- operation optical fiber, 2- fiber core, 3- fixed part, 4- control line, 5- sheath, 6- operation portion, 7-, which is turned to, to be revolved Button.
Specific embodiment
In order to be more clear goal of the invention of the invention, technical solution and advantageous effects, with reference to embodiments, The present invention will be described in further detail.It should be understood that embodiment described in this specification is just for the sake of explanation The present invention, be not intended to limit the present invention, formula, ratio of embodiment etc. can adaptation to local conditions make a choice and reality had no to result Matter influences.
Embodiment 1
As shown in Figure 1, the present invention devises a kind of laser surgey optical fiber 1 of the flexible end with optothermal material, institute It states operation 1 front end of optical fiber and is provided with fixed part 3, four control lines 4 are fixed on the fixed part 3, the control line 4 can be controlled The operation fibre-optical bending is made, is formed with optothermal material in the distal end faces of the operation optical fiber 1, the optothermal material covers light The area of fine end face 5%.
The operation optical fiber 1 can be used cooperatively with endoscope, and the work that endoscope can be inserted in the operation optical fiber 1 is logical In road, and it can be moved axially in the service aisle.
The optothermal material covering part fiber end face, in this way, the efficient photothermal conversion of optothermal material improves the production of probe Thermal energy power improves fiber optic temperature, but does not influence the output of laser.The covering shape of the optothermal material can be according to practical need It is arranged, for example can is shapes such as circle, annulus, spot distribution, threadiness, radial or combinations thereof.
As shown in Fig. 2, the operation optical fiber 1 includes operation portion 6, the operation portion 6 is provided with for pulling the control The component steering knob 7 of line 4, user pull the control line 4 by steering knob 7, to control the curved of the operation optical fiber 1 It is bent.
The operation optical fiber 1 includes fibre core 2 and the covering for being sheathed on fibre core surface, and the covering includes inner cladding and outsourcing Layer, doped aluminium or germanium oxide in the inner cladding improve the refractive index of inner cladding, reduce the numerical aperture of fibre core, be arranged Surrounding layer on the inner cladding surface includes silica.
The operation optical fiber 1 includes sheath 5 made of resin, and the sheath 5 is arranged after surrounding layer, the control Line 4 is arranged in the resin sheath.Four control lines are circumferentially uniformly distributed.
The optothermal material can pass through any one method shape in coating, vapor deposition, magnetron sputtering, vapor deposition, welding The surface of optical fiber described in Cheng Yu.Welding carries out under protective atmosphere, using the atmosphere by He gas composition, can effectively prevent in this way The only oxidation of material under high temperature.
The optothermal material can be one of metal optothermal material, diamond or semiconductor light hot material or a variety of.
The photo-thermal nano material can be metal photo-thermal nano material, Nano diamond or semiconductor photo-thermal nano material One of or it is a variety of.
The metal photo-thermal nano material can be one of gold, platinum, nanometer Pd material or a variety of.
The semiconductor photo-thermal nano material can for copper sulfide, molybdenum sulfide, bismuth sulfide, antimony trisulfide, aurosulfo copper selenide, One of selenizing molybdenum, bismuth selenide, antimony selenide or Auric selenide are a variety of.
Embodiment 2
As shown in Figure 1, the present invention devises a kind of laser surgey optical fiber 1 of the flexible end with optothermal material, institute It states operation 1 front end of optical fiber and is provided with fixed part 3, four control lines 4 are fixed on the fixed part 3, the control line 4 can be controlled The operation fibre-optical bending is made, is formed with optothermal material in the distal end faces of the operation optical fiber 1, the optothermal material covers light The area of fine end face 60%.
The operation optical fiber 1 can be used cooperatively with endoscope, and the work that endoscope can be inserted in the operation optical fiber 1 is logical In road, and it can be moved axially in the service aisle.
The optothermal material covering part fiber end face, in this way, the efficient photothermal conversion of optothermal material improves the production of probe Thermal energy power improves fiber optic temperature, but does not influence the output of laser.The covering shape of the optothermal material can be according to practical need It is arranged, for example can is shapes such as circle, annulus, spot distribution, threadiness, radial or combinations thereof.
As shown in Fig. 2, the operation optical fiber 1 includes operation portion 6, the operation portion 6 is provided with for pulling the control The component steering knob 7 of line 4, user pull the control line 4 by steering knob 7, to control the curved of the operation optical fiber 1 It is bent.
The operation optical fiber 1 includes fibre core 2 and the covering for being sheathed on fibre core surface, and the covering includes inner cladding and outsourcing Layer, doped aluminium or germanium oxide in the inner cladding improve the refractive index of inner cladding, reduce the numerical aperture of fibre core, be arranged Surrounding layer on the inner cladding surface includes silica.
The operation optical fiber 1 includes sheath 5 made of resin, and the sheath 5 is arranged after surrounding layer, the control Line 4 is arranged in the resin sheath.Four control lines are circumferentially uniformly distributed.
The optothermal material can pass through any one method shape in coating, vapor deposition, magnetron sputtering, vapor deposition, welding The surface of optical fiber described in Cheng Yu.Welding carries out under protective atmosphere, using the atmosphere by He gas composition, can effectively prevent in this way The only oxidation of material under high temperature.
The optothermal material can be one of metal optothermal material, diamond or semiconductor light hot material or a variety of.
The photo-thermal nano material can be metal photo-thermal nano material, Nano diamond or semiconductor photo-thermal nano material One of or it is a variety of.
The metal photo-thermal nano material can be one of gold, platinum, nanometer Pd material or a variety of.
The semiconductor photo-thermal nano material can for copper sulfide, molybdenum sulfide, bismuth sulfide, antimony trisulfide, aurosulfo copper selenide, One of selenizing molybdenum, bismuth selenide, antimony selenide or Auric selenide are a variety of.
Embodiment 3
As shown in Figure 1, the present invention devises a kind of laser surgey optical fiber 1 of the flexible end with optothermal material, institute It states operation 1 front end of optical fiber and is provided with fixed part 3, four control lines 4 are fixed on the fixed part 3, the control line 4 can be controlled The operation fibre-optical bending is made, is formed with optothermal material in the distal end faces of the operation optical fiber 1, the optothermal material covers light The area of fine end face 35%.
The operation optical fiber 1 can be used cooperatively with endoscope, and the work that endoscope can be inserted in the operation optical fiber 1 is logical In road, and it can be moved axially in the service aisle.
The optothermal material covering part fiber end face, in this way, the efficient photothermal conversion of optothermal material improves the production of probe Thermal energy power improves fiber optic temperature, but does not influence the output of laser.The covering shape of the optothermal material can be according to practical need It is arranged, for example can is shapes such as circle, annulus, spot distribution, threadiness, radial or combinations thereof.
As shown in Fig. 2, the operation optical fiber 1 includes operation portion 6, the operation portion 6 is provided with for pulling the control The component steering knob 7 of line 4, user pull the control line 4 by steering knob 7, to control the curved of the operation optical fiber 1 It is bent.
The operation optical fiber 1 includes fibre core 2 and the covering for being sheathed on fibre core surface, and the covering includes inner cladding and outsourcing Layer, doped aluminium or germanium oxide in the inner cladding improve the refractive index of inner cladding, reduce the numerical aperture of fibre core, be arranged Surrounding layer on the inner cladding surface includes silica.
The operation optical fiber 1 includes sheath 5 made of resin, and the sheath 5 is arranged after surrounding layer, the control Line 4 is arranged in the resin sheath.Four control lines are circumferentially uniformly distributed.
The optothermal material can pass through any one method shape in coating, vapor deposition, magnetron sputtering, vapor deposition, welding The surface of optical fiber described in Cheng Yu.Welding carries out under protective atmosphere, using the atmosphere by He gas composition, can effectively prevent in this way The only oxidation of material under high temperature.
The optothermal material can be one of metal optothermal material, diamond or semiconductor light hot material or a variety of.
The photo-thermal nano material can be metal photo-thermal nano material, Nano diamond or semiconductor photo-thermal nano material One of or it is a variety of.
The metal photo-thermal nano material can be one of gold, platinum, nanometer Pd material or a variety of.
The semiconductor photo-thermal nano material can for copper sulfide, molybdenum sulfide, bismuth sulfide, antimony trisulfide, aurosulfo copper selenide, One of selenizing molybdenum, bismuth selenide, antimony selenide or Auric selenide are a variety of.
The preferred embodiment of the patent is described in detail above, but this patent is not limited to above-mentioned embodiment party Formula within the knowledge of one of ordinary skill in the art can also be under the premise of not departing from this patent objective It makes a variety of changes.

Claims (10)

1. a kind of laser surgey optical fiber of flexible end with optothermal material, which is characterized in that the operation optical fiber front end It is provided with fixed part, control line is fixed on the fixed part, the control line can control the operation fibre-optical bending, described Optothermal material is formed in the distal end faces of operation optical fiber, the optothermal material covers the area of fiber end face 30%~50%, The high temperature and laser of fiber tip act on tissue simultaneously.
2. laser surgey optical fiber according to claim 1, which is characterized in that the operation optical fiber is inserted into endoscope In service aisle, and it can be moved axially in the service aisle.
3. laser surgey optical fiber according to claim 1, which is characterized in that the covering shape of the optothermal material is circle Shape, annulus, spot distribution, threadiness, radial or combinations thereof.
4. laser surgey optical fiber according to claim 1, which is characterized in that the operation optical fiber includes operation portion, described Operation portion is provided with the component for pulling the control line, and user is by pulling the control line, to control the operation The bending of optical fiber.
5. laser surgey optical fiber according to claim 1, which is characterized in that the operation optical fiber includes fibre core and is sheathed on The covering on fibre core surface, the covering include inner cladding and surrounding layer, and doped aluminium or germanium oxide, are arranged in the inner cladding Surrounding layer on the inner cladding surface includes silica.
6. laser surgey optical fiber according to claim 1, which is characterized in that the operation optical fiber includes made of resin Sheath, the sheath are arranged after surrounding layer, and the control line is arranged in the resin sheath.
7. laser surgey optical fiber according to claim 1, which is characterized in that the control line is two or four.
8. laser surgey optical fiber according to claim 1, which is characterized in that the optothermal material is heavy by coating, gas phase Product, magnetron sputtering, vapor deposition, any one method is formed in the surface of the optical fiber in welding.
9. laser surgey optical fiber according to claim 1, which is characterized in that the optothermal material be metal optothermal material, One of diamond or semiconductor light hot material are a variety of.
10. laser surgey optical fiber according to claim 1, which is characterized in that the optothermal material covering fiber end face Area control is 35%.
CN201811494964.0A 2018-12-07 2018-12-07 A kind of laser surgey optical fiber of the flexible end with optothermal material Active CN109452969B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103293593A (en) * 2013-05-27 2013-09-11 上海大学 Buckling and deforming optical fiber and application thereof in endoscopic catheter
CN104840251A (en) * 2015-05-07 2015-08-19 上海大学 Laser thermal therapy probe based on photothermal effect of optical fiber material
CN107412957A (en) * 2017-07-12 2017-12-01 华东师范大学 A kind of photo-thermal therapy probe based on photo-thermal nano material

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4261167B2 (en) * 2002-11-29 2009-04-30 Hoya株式会社 Photothermal actuator and device equipped with photothermal actuator

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103293593A (en) * 2013-05-27 2013-09-11 上海大学 Buckling and deforming optical fiber and application thereof in endoscopic catheter
CN104840251A (en) * 2015-05-07 2015-08-19 上海大学 Laser thermal therapy probe based on photothermal effect of optical fiber material
CN107412957A (en) * 2017-07-12 2017-12-01 华东师范大学 A kind of photo-thermal therapy probe based on photo-thermal nano material

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