CN109567934A - A kind of double optical-fiber laser treatment systems - Google Patents

A kind of double optical-fiber laser treatment systems Download PDF

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Publication number
CN109567934A
CN109567934A CN201811494995.6A CN201811494995A CN109567934A CN 109567934 A CN109567934 A CN 109567934A CN 201811494995 A CN201811494995 A CN 201811494995A CN 109567934 A CN109567934 A CN 109567934A
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China
Prior art keywords
laser
light
fiber
contact
optical fiber
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CN201811494995.6A
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CN109567934B (en
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梁瑶
詹凯
傅喜泉
王洪波
潘友华
李泊文
梁雷
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China Polytron Technologies Inc
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China Polytron Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared

Abstract

The present invention provides a kind of double optical-fiber laser treatment systems, by the way that two laser transmission channels are arranged, optothermal material wherein is set on the end face of contact type optical fiber, the Thermogenesis of probe is improved using the efficient photothermal conversion of optothermal material, improve optical fiber connector temperature, it is directly contacted with tissue in the course of surgery, the laser with non-contact fiber outgoing cooperates again, so that high temperature and laser act on tissue simultaneously, so that procedure efficiency greatly improves, required laser power is many compared to the decline of traditional fiber non-contact method, reduces the generation of the fuel factor problem of optical fiber.Laser probe uses changeable type structure, after first use, replaces cutter head, does not have to replacement laser conduction optical fiber, is greatly saved consuming cost.

Description

A kind of double optical-fiber laser treatment systems
Technical field
The present invention relates to area of medical devices, and in particular to a kind of double optical-fiber laser treatment systems.
Background technique
Laser is because of extraordinary cutting power, good coagulating effectiveness and lesser thermal damage, in surgical field It gets the attention.The high energy pulse laser that laser generates, is passed out by optical fiber, and optical fiber is entered by endoscope again Human body, by the incoming position for needing laser therapy of the energy of laser, using the high energy, collimation, action time of laser it is short and The features such as heat-affected zone is small carries out treatment effectively and safely for patient.Laser is doctor to the interaction of bio-tissue The physical basis of application is learned, the fuel factor of laser is medically to imitate using the laser tissue being most recognized extensively and earliest One of answer.Laser light incident bio-tissue, within the scope of light penetration depth, absorbed luminous energy is converted into heat.When heating speed Needed for degree (thermal energy comes from laser irradiation, related with laser intensity and two factors of tissue absorption coefficient) significantly larger than evaporation tissue The speed of heat, then tissue is by vaporization quickly.
The laser of the exportable 1.65~2.1um wavelength of thulium-doped fiber laser is widest in all rare earth ions, phase For solid state laser, have that structure is simple, high-efficient, heat dissipation characteristics are good, narrow linewidth, quality for outputting laser beam height etc. are excellent Point, thus the thulium optical fiber laser of high peak power pulse output had obtained extensive research in recent years.But thulium is mixed near 2 μm Optical fiber laser the operations such as is cut to tissue, is gasified and needing biggish pulse energy, and laser power is mainly by mixing thulium Fibre core provides.But with the significant reinforcement for mixing optical power density in thulium gain fibre, it may appear that serious fuel factor causes thermotropic Phenomena such as birefringent, phase distortion, hot focus, thermal lens, seriously affects the output power and beam quality of laser, becomes limitation The lethal factor that laser performance improves.
It is sharp that the Chinese invention patent of Publication No. CN104638506A discloses a kind of 1.9 microns of high-power prostates Photo-therapeutic instrument can carry out the compensation of different modes for different operation power, solve thulium-doped fiber laser to increase Power and occur efficiency decline and beam quality be deteriorated the problems such as.But the fuel factor that this scheme still can not solve optical fiber is asked Topic.
CN107412957A discloses a kind of photo-thermal therapy probe based on photo-thermal nano material comprising closed at one end Cylinder-like shell, the photo-thermal nano material for being filled in interior of shell closed end kill tumour and other diseases by implementing high temperature Become histocyte.But this scheme is implemented to treat only with high temperature, and it closes nano material inside the shell, knot Structure is complicated, heat production low efficiency.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of double optical-fiber laser treatment systems, by the way that two lasers are arranged Wherein optothermal material is arranged on the end face of contact type optical fiber in defeated channel, improves probe using the efficient photothermal conversion of optothermal material Thermogenesis, improve optical fiber connector temperature, directly contacted with tissue in the course of surgery, then is with non-contact fiber outgoing sharp Light cooperation, so that high temperature and laser act on tissue simultaneously, so that procedure efficiency greatly improves, required laser power is compared to biography There are many optical fiber non-contact method decline of uniting, and reduce the generation of the fuel factor problem of optical fiber.Laser probe uses changeable type Structure after first use, replaces cutter head, does not have to replacement laser conduction optical fiber, is greatly saved consuming cost.
Technical solution of the present invention specifically:
A kind of double optical-fiber laser treatment systems, the system comprises laser light source and device for laser therapy, the laser is controlled Treating device includes insertion tube, and service aisle is provided in the insertion tube, and contact laser biography is provided in the service aisle Fine and non-contact laser transmission fiber is lost, wherein contact laser transmission fiber includes hop and light out part point, institute It states light out part point removably to connect with the hop, and is formed with photo-thermal material in the distal end faces of the light out part point Material, the contact laser transmission fiber can be axially moveable in service aisle, the laser light source include mix thulium light source and Infrared light supply.
The optothermal material covers fiber end face, and the efficient photothermal conversion of optothermal material improves the Thermogenesis of probe, mentions High fiber optic temperature.Contact laser optical fiber of the end face with optothermal material transmits infrared light, the transmission of non-contact laser transmission fiber From the output laser for mixing thulium gain fibre.
In the course of surgery, contact laser transmission fiber can stretch out service aisle, directly be contacted with tissue.
It is preferred that contact laser transmission fiber and non-contact laser transmission fiber are located at different service aisles, it is non-to connect Service aisle end has transparent light exit window where touch laser transmission fiber, and optical fiber will not be contaminated in use, It may be reused.
The optothermal material can pass through any one method shape in coating, vapor deposition, magnetron sputtering, vapor deposition, welding The surface of optical fiber described in Cheng Yu.Welding carries out under protective atmosphere, using the atmosphere by He gas composition, can effectively prevent in this way The only oxidation of material under high temperature.
The optothermal material can be one of metal optothermal material, diamond or semiconductor light hot material or a variety of.
It is preferred that the optothermal material is nano material.
The photo-thermal nano material can be metal photo-thermal nano material, Nano diamond or semiconductor nano optothermal material One of or it is a variety of.
The metal photo-thermal nano material can be one of gold, platinum, nanometer Pd material or a variety of.
The semiconductor nano material can be copper sulfide, molybdenum sulfide, bismuth sulfide, antimony trisulfide, aurosulfo copper selenide, selenizing One of molybdenum, bismuth selenide, antimony selenide or Auric selenide are a variety of.
According to the density and thickness that optothermal material is arranged needed for laser power and clinical temperature.For example, thickness can be 100 microns hereinafter, further, 50 microns hereinafter, further, 1 micron hereinafter, further, 500 nanometers or less and not small In 1 nanometer.
The laser light source includes pumping source, beam splitter, resonant cavity, and resonant cavity includes two hysteroscopes and doping gain light Fibre, two hysteroscopes are semi-transparent semi-reflecting lens, and the first hysteroscope transmits pump light, the signal light that reflection gain optical fiber generates, the second chamber The signal light that mirror transmittance gain optical fiber generates, reflected pump light, beam splitter can control the pumping light quantity into resonant cavity.
Pumping source uses near-infrared semiconductor laser pumping.
The beam splitter structure includes three blades, and one of blade is half-silvered mirror, so that simultaneously with 45 degree of angle incidences And the not part (transmission light quantity can be controlled by the thickness or coating area for controlling deposit) of light that coated absorbs It is transmitted, rest part is reflected, and a blade is total reflection mirror, another blade is total transmissivity mirror.The beam splitter can To be rotated as needed around axle center, controls any of three blades and be located in optical path.When such as carrying out optical dynamic therapy, make to be all-trans It penetrates mirror to be located in optical path, reflects whole pump lights, in this way, optical fiber output near infrared light is used for optical dynamic therapy.Such as carry out laser When treatment, it is located at full projecting mirror in optical path, transmits whole pump lights, pump light enters resonant cavity and generates output laser, optical fiber It exports 2um high energy pulse laser and is used for laser therapy.When being used cooperatively such as optical dynamic therapy and laser therapy, make half-silvered mirror position In optical path, reflective portion pump light, transmissive portion pump light.
It is preferred that the half-silvered mirror can be replaced as needed, regulated and controled by using the half-silvered mirror of different transmittance example Export the ratio of near-infrared and 2um high energy pulse laser.
The half-silvered mirror can using in a sheet glass or plastics splash-proofing sputtering metal coating, formed discontinuous coating or Continuous coated zonule is removed by chemically or mechanically acting on to generate.
The hop of contact type optical fiber is connected through a screw thread or is connected together realization with the light out part point can Dismantling connection.Sheath of the light out part point with covering service aisle.The sheath covers service aisle, can prevent steam Into service aisle, the pollution to service aisle is prevented.
The sheath is made of elastic material, it is preferred to use rubber material is made.
The service aisle edge protrusion endoscope tip plane certain length is used for the fixation of the sheath.
Optionally, the service aisle bordered profiles circularize the fixation that recess is used for the sheath.
The contact type optical fiber can be axially moveable in service aisle, and the service aisle front end is provided with and contacts The bayonet of formula optical fiber cooperation, the bayonet include the elastic brake lining for closing bayonet, and bayonet outer is provided with opening for control brake lining It closes, opens brake lining, the hop can stretch out bayonet, connect with the cutter head, after treatment end, to the cutter head and institute It states sheath to be cleaned, releases connection of the light out part point with the hop, the hop is withdrawn into bayonet, lock Piece rebounds automatically, closes bayonet, then releases being fixedly connected for the sheath and service aisle, in this way, only needing after primary operation Disinfection is purged to external tothe endoscope, without carrying out cleaning and sterilizing to endoscopic working channel.
The shape of the brake lining can according to need setting, can be two semicircle brake linings, or multiple triangles Blade.
Further, described device includes the temperature sensor being arranged near optic fibre end, is monitored to temperature.
Further, described device includes cooling and flushing channel, is used for by liquid injection to target site, to target portion It is cleaned and is cooled down in position.
Be compared with the prior art, the present invention there are following the utility model has the advantages that
1, probe gets involved in lesion tissue position by minimally invasive, then passes through the optothermal material on wherein contact type optical fiber end face Efficient photothermal conversion mechanism, improve fiber optic temperature, carry out surgical operation of the optical Fiber Contact with non-contact laser in conjunction with, height Mild laser acts on tissue simultaneously and procedure efficiency is greatly improved, have laser surgey high energy, collimation, action time it is short with And the feature that heat-affected zone is small, while required laser power is many compared to the decline of traditional fiber non-contact method, reduces The generation of the fuel factor problem of optical fiber.
2, optical fiber is directly contacted with optothermal material in the present invention, and structure is simple, in addition also greatly reduces laser energy Loss.
3, system complexity is low.Since this product power is low, and when work, other parts temperature will not be risen other than syringe needle Height greatly reduces system complexity so not needing water-cooling system.
4, laser probe uses changeable type structure, after first use, replaces cutter head, and it is guide-lighting not have to replacement laser Fibre is greatly saved consuming cost.
Detailed description of the invention
Fig. 1 is device for laser therapy structural schematic diagram.
Fig. 2 is laser light source structural schematic diagram.
Fig. 3 is jacket structure schematic diagram.
In figure, 1- non-contact laser transmission fiber, 2- contact laser transmission fiber, 3- optothermal material, 4- doping increasing Beneficial the second hysteroscope of optical fiber 5- 6- bundling device.
Specific embodiment
In order to be more clear goal of the invention of the invention, technical solution and advantageous effects, with reference to embodiments, The present invention will be described in further detail.It should be understood that embodiment described in this specification is just for the sake of explanation The present invention, be not intended to limit the present invention, embodiment design parameter setting etc. can adaptation to local conditions make a choice and simultaneously to result Without substantial effect.
Embodiment 1
As shown in Figure 1, a kind of double optical-fiber laser treatment systems, the system comprises laser light source and device for laser therapy, The device for laser therapy includes insertion tube, and service aisle is provided in the insertion tube, is provided with and connects in the service aisle Touch laser transmission fiber 2 and non-contact laser transmission fiber 1, wherein contact laser transmission fiber 2 includes hop And light out part point, the light out part point are removably connect with the hop, and in the distal end faces of the light out part point It is formed with optothermal material, and can be axially moveable in service aisle, the laser light source includes mixing thulium light source and infrared light supply.
The optothermal material 3 covers fiber end face, and the efficient photothermal conversion of optothermal material improves the Thermogenesis of probe, mentions High fiber optic temperature.Contact laser optical fiber 2 of the end face with optothermal material 3 transmits infrared light, and non-contact laser transmission fiber 1 passes It is defeated from the output laser for mixing thulium gain fibre.
In the course of surgery, contact laser transmission fiber 2 can stretch out service aisle, directly be contacted with tissue.
Contact laser transmission fiber 2 and non-contact laser transmission fiber 1 are located at different service aisles, contactless 1 place service aisle end of laser transmission fiber has transparent light exit window 9, and optical fiber will not be contaminated in use, can To reuse.
The optothermal material 3 can pass through any one method shape in coating, vapor deposition, magnetron sputtering, vapor deposition, welding The surface of optical fiber described in Cheng Yu.Welding carries out under protective atmosphere, using the atmosphere by He gas composition, can effectively prevent in this way The only oxidation of material under high temperature.
The optothermal material can be one of metal optothermal material, diamond or semiconductor material or a variety of.
The optothermal material is nano material.
The photo-thermal nano material can be in metal photo-thermal nano material, Nano diamond or semiconductor nano material It is one or more.
The metal photo-thermal nano material can be one of gold, platinum, nanometer Pd material or a variety of.
The semiconductor nano material can be copper sulfide, molybdenum sulfide, bismuth sulfide, antimony trisulfide, aurosulfo copper selenide, selenizing One of molybdenum, bismuth selenide, antimony selenide or Auric selenide are a variety of.
According to the density and thickness that optothermal material is arranged needed for laser power and clinical temperature.For example, thickness can be 100 microns hereinafter, further, 50 microns hereinafter, further, 1 micron hereinafter, further, 500 nanometers or less and not small In 1 nanometer.
As shown in Fig. 2, the laser light source includes pumping source 4, beam splitter 8 and resonant cavity, resonant cavity includes two chambers Mirror 5,7 and doped gain fiber 6, two hysteroscopes 5,7 are semi-transparent semi-reflecting lens, and the first hysteroscope 5 transmits pump light, reflection gain light Fibre generate signal light, 7 transmittance gain optical fiber of the second hysteroscope generate signal light, reflected pump light, beam splitter 8 can control into Enter the pumping light quantity of resonant cavity.
Pumping source 4 uses near-infrared semiconductor laser pumping.
The beam splitter structure 8 includes three blades, and one of blade is half-silvered mirror, so that simultaneously with 45 degree of angle incidences And the not part (transmission light quantity can be controlled by the thickness or coating area for controlling deposit) of light that coated absorbs It is transmitted, rest part is reflected, and a blade is total reflection mirror, another blade is total transmissivity mirror.The beam splitter can To be rotated as needed around axle center, controls any of three blades and be located in optical path.When such as carrying out optical dynamic therapy, make to be all-trans It penetrates mirror to be located in optical path, reflects whole pump lights, in this way, optical fiber output near infrared light is used for optical dynamic therapy.Such as carry out laser When treatment, it is located at full projecting mirror in optical path, transmits whole pump lights, pump light enters resonant cavity and generates output laser, optical fiber It exports 2um high energy pulse laser and is used for laser therapy.When being used cooperatively such as optical dynamic therapy and laser therapy, make half-silvered mirror position In optical path, reflective portion pump light, transmissive portion pump light.
The half-silvered mirror can be replaced as needed, and it is close to regulate and control output by using the half-silvered mirror of different transmittance example The infrared ratio with 2um high energy pulse laser.
The half-silvered mirror can using in a sheet glass or plastics splash-proofing sputtering metal coating, formed discontinuous coating or Continuous coated zonule is removed by chemically or mechanically acting on to generate.
The hop of contact type optical fiber 2 is connected through a screw thread or is connected together realization with the light out part point can Dismantling connection.Sheath of the light out part point with covering service aisle as shown in Figure 3.The sheath covers service aisle, It can prevent steam from entering service aisle, prevent the pollution to service aisle.
The sheath is made of elastic material, it is preferred to use rubber material is made.
The service aisle edge protrusion endoscope tip plane certain length is used for the fixation of the sheath.
The service aisle bordered profiles circularize the fixation that recess is used for the sheath.
The contact type optical fiber 2 can be axially moveable in service aisle, and the service aisle front end is provided with and connects The bayonet of touch optical fiber cooperation, the bayonet include the elastic brake lining for closing bayonet, and bayonet outer is provided with control brake lining Switch opens brake lining, and the hop can stretch out bayonet, connect with the cutter head, after treatment end, to the cutter head and The sheath is cleaned, and connection of the light out part point with the hop is released, and the hop is withdrawn bayonet, Brake lining rebounds automatically, closes bayonet, then releases being fixedly connected for the sheath and service aisle, in this way, after primary operation, only Disinfection need to be purged to external tothe endoscope, without carrying out cleaning and sterilizing to endoscopic working channel.
The shape of the brake lining can according to need setting, can be two semicircle brake linings, or multiple triangles Blade.
Described device includes the temperature sensor being arranged near optic fibre end, is monitored to temperature.
Described device includes cooling and flushing channel, for carrying out liquid injection to target site to target site clear It washes and cools down.
The preferred embodiment of the patent is described in detail above, but this patent is not limited to above-mentioned embodiment party Formula within the knowledge of one of ordinary skill in the art can also be under the premise of not departing from this patent objective It makes a variety of changes.

Claims (10)

1. a kind of double optical-fiber laser treatment systems, which is characterized in that the system comprises laser light source and device for laser therapy, institutes Stating device for laser therapy includes insertion tube, and service aisle is provided in the insertion tube, contact is provided in the service aisle Formula laser transmission fiber and non-contact laser transmission fiber, wherein contact laser transmission fiber includes hop and light out Part, the light out part point are removably connect with the hop, and are formed in the distal end faces of the light out part point Optothermal material, the contact laser transmission fiber can be axially moveable in service aisle, and the laser light source includes mixing thulium Light source and infrared light supply.
2. laser therapeutic system according to claim 1, which is characterized in that contact of the end face with optothermal material swashs Light optical fiber transmits infrared light, and the non-contact laser transmission fiber transmission is from the output laser for mixing thulium gain fibre.
3. laser therapeutic system according to claim 1, which is characterized in that contact laser transmission fiber and contactless Laser transmission fiber is located at different service aisles, and service aisle end has transparent light where non-contact laser transmission fiber Exit window.
4. laser therapeutic system according to claim 1, which is characterized in that the optothermal material is heavy by coating, gas phase Product, magnetron sputtering, vapor deposition, any one method is formed in the surface of the optical fiber in welding.
5. laser therapeutic system according to claim 1, which is characterized in that the photo-thermal nano material is that metal photo-thermal is received One of rice material, Nano diamond or semiconductor nano optothermal material are a variety of.
6. laser therapeutic system according to claim 1, which is characterized in that the laser light source includes pumping source, beam splitting Device and resonant cavity, resonant cavity include two hysteroscopes and doped gain fiber, and two hysteroscopes are semi-transparent semi-reflecting lens, the first hysteroscope Transmit pump light, the signal light that reflection gain optical fiber generates, the signal light that the second hysteroscope transmittance gain optical fiber generates, reflection pumping Light, beam splitter can control the pumping light quantity into resonant cavity.
7. laser therapeutic system according to claim 6, which is characterized in that pumping source is pumped using near-infrared semiconductor laser Pu.
8. laser therapeutic system according to claim 1, which is characterized in that the hop of contact type optical fiber is with institute Stating light out part divides the realization that is connected through a screw thread or is connected together to be detachably connected.
9. laser therapeutic system according to claim 1, which is characterized in that the light out part point is with covering service aisle Sheath.
10. laser therapeutic system according to claim 9, which is characterized in that the sheath is made of elastic material.
CN201811494995.6A 2018-12-07 2018-12-07 Double-optical-fiber laser treatment system Active CN109567934B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114406499A (en) * 2022-02-24 2022-04-29 桂林市啄木鸟医疗器械有限公司 Laser cutting device and laser cutting method

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Publication number Priority date Publication date Assignee Title
US4273109A (en) * 1976-07-06 1981-06-16 Cavitron Corporation Fiber optic light delivery apparatus and medical instrument utilizing same
CN1415388A (en) * 2002-11-13 2003-05-07 吉林大学 Therapeutic apparatus combining light and heat for curing prostate
CN102688095A (en) * 2012-06-15 2012-09-26 上海安通医疗科技有限公司 Laser ablation conduit for renal artery
WO2015160064A1 (en) * 2014-04-18 2015-10-22 부경대학교산학협력단 Probe comprising optically diffusing fiber, method for manufacturing same and applications thereof
CN107412957A (en) * 2017-07-12 2017-12-01 华东师范大学 A kind of photo-thermal therapy probe based on photo-thermal nano material
CN108577964A (en) * 2018-04-25 2018-09-28 南京市口腔医院 Semiconductor laser therapeutic instrument, control method and temperature signal processing method

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273109A (en) * 1976-07-06 1981-06-16 Cavitron Corporation Fiber optic light delivery apparatus and medical instrument utilizing same
CN1415388A (en) * 2002-11-13 2003-05-07 吉林大学 Therapeutic apparatus combining light and heat for curing prostate
CN102688095A (en) * 2012-06-15 2012-09-26 上海安通医疗科技有限公司 Laser ablation conduit for renal artery
WO2015160064A1 (en) * 2014-04-18 2015-10-22 부경대학교산학협력단 Probe comprising optically diffusing fiber, method for manufacturing same and applications thereof
CN107412957A (en) * 2017-07-12 2017-12-01 华东师范大学 A kind of photo-thermal therapy probe based on photo-thermal nano material
CN108577964A (en) * 2018-04-25 2018-09-28 南京市口腔医院 Semiconductor laser therapeutic instrument, control method and temperature signal processing method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114406499A (en) * 2022-02-24 2022-04-29 桂林市啄木鸟医疗器械有限公司 Laser cutting device and laser cutting method

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