CN109563516B - Gpr156变体及其用途 - Google Patents

Gpr156变体及其用途 Download PDF

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Publication number
CN109563516B
CN109563516B CN201780048589.4A CN201780048589A CN109563516B CN 109563516 B CN109563516 B CN 109563516B CN 201780048589 A CN201780048589 A CN 201780048589A CN 109563516 B CN109563516 B CN 109563516B
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seq
nucleic acid
gpr156
acid sequence
protein
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Chinese (zh)
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CN109563516A (zh
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克劳迪娅·贡萨加-贾雷吉
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
CN201780048589.4A 2016-07-28 2017-07-28 Gpr156变体及其用途 Active CN109563516B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662367973P 2016-07-28 2016-07-28
US62/367,973 2016-07-28
PCT/US2017/044321 WO2018022967A1 (en) 2016-07-28 2017-07-28 Gpr156 variants and uses thereof

Publications (2)

Publication Number Publication Date
CN109563516A CN109563516A (zh) 2019-04-02
CN109563516B true CN109563516B (zh) 2023-10-27

Family

ID=59649989

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Application Number Title Priority Date Filing Date
CN201780048589.4A Active CN109563516B (zh) 2016-07-28 2017-07-28 Gpr156变体及其用途

Country Status (13)

Country Link
US (4) US10266582B2 (enExample)
EP (2) EP4230648A3 (enExample)
JP (2) JP7556688B2 (enExample)
KR (2) KR102661616B1 (enExample)
CN (1) CN109563516B (enExample)
AU (1) AU2017302611B2 (enExample)
CA (1) CA3032124A1 (enExample)
DK (1) DK3491014T5 (enExample)
IL (1) IL264473A (enExample)
MX (2) MX2019001084A (enExample)
NZ (1) NZ751010A (enExample)
SG (1) SG11201900738YA (enExample)
WO (1) WO2018022967A1 (enExample)

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* Cited by examiner, † Cited by third party
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EP4230648A3 (en) * 2016-07-28 2023-10-18 Regeneron Pharmaceuticals, Inc. Gpr156 variants and uses thereof
SG11202001754RA (en) 2017-09-06 2020-03-30 Regeneron Pharma Single immunoglobulin interleukin-1 receptor related (sigirr) variants and uses thereof
PL3505157T3 (pl) 2017-12-29 2022-04-11 Celon Pharma S.A. Kompozycja ketaminy w postaci suchego proszku do podawania dopłucnego w leczeniu depresji opornej na leczenie
WO2020087031A1 (en) 2018-10-26 2020-04-30 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
AU2020209184A1 (en) * 2019-01-17 2021-07-08 Regeneron Pharmaceuticals, Inc. A rodent model of mood disorders

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CN1946685A (zh) * 2004-04-29 2007-04-11 默克公司 氮杂环丁烷甘氨酸转运蛋白抑制剂

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CN1946685A (zh) * 2004-04-29 2007-04-11 默克公司 氮杂环丁烷甘氨酸转运蛋白抑制剂

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AU2017302611A1 (en) 2019-03-14
US10266582B2 (en) 2019-04-23
DK3491014T3 (da) 2023-05-30
EP3491014B1 (en) 2023-04-05
US11155598B2 (en) 2021-10-26
KR102661616B1 (ko) 2024-04-30
CA3032124A1 (en) 2018-02-01
WO2018022967A1 (en) 2018-02-01
CN109563516A (zh) 2019-04-02
EP4230648A3 (en) 2023-10-18
US20190202891A1 (en) 2019-07-04
US20200231651A1 (en) 2020-07-23
NZ751010A (en) 2024-11-29
JP2023071704A (ja) 2023-05-23
US10562953B2 (en) 2020-02-18
EP3491014A1 (en) 2019-06-05
KR20190034532A (ko) 2019-04-02
AU2017302611B2 (en) 2021-12-09
IL264473A (en) 2019-02-28
KR20240027874A (ko) 2024-03-04
SG11201900738YA (en) 2019-02-27
JP2019527229A (ja) 2019-09-26
MX2024013403A (es) 2024-12-06
US20220073589A1 (en) 2022-03-10
DK3491014T5 (da) 2024-09-02
MX2019001084A (es) 2019-06-10
JP7556688B2 (ja) 2024-09-26
US20180030114A1 (en) 2018-02-01
EP4230648A2 (en) 2023-08-23

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