CN109562188B - 与三价糖缀合物连接的核酸 - Google Patents

与三价糖缀合物连接的核酸 Download PDF

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CN109562188B
CN109562188B CN201780035060.9A CN201780035060A CN109562188B CN 109562188 B CN109562188 B CN 109562188B CN 201780035060 A CN201780035060 A CN 201780035060A CN 109562188 B CN109562188 B CN 109562188B
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CN109562188A (zh
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克里斯蒂安·弗劳恩多夫
马克·卡梅伦
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Silence Therapeutics GmbH
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CN201780035060.9A 2016-04-05 2017-04-05 与三价糖缀合物连接的核酸 Active CN109562188B (zh)

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EP16163939.8 2016-04-05
EP16163939.8A EP3228326A1 (en) 2016-04-05 2016-04-05 Nucleic acid linked to a trivalent glycoconjugate
PCT/EP2017/058112 WO2017174657A1 (en) 2016-04-05 2017-04-05 Nucleic acid linked to a trivalent glycoconjugate

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JP2023547512A (ja) 2020-11-04 2023-11-10 ウニベルジテート ベルン 細胞におけるpros1の発現を阻害するための核酸
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WO2022223557A1 (en) 2021-04-20 2022-10-27 Silence Therapeutics Gmbh Nucleic acids for inhibiting expression of xdh in a cell
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CN116444589B (zh) * 2023-06-15 2023-09-19 北京悦康科创医药科技股份有限公司 新型GalNAc化合物及其硫代寡核苷酸缀合物和偶联方法
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WO2017174657A1 (en) 2017-10-12
JP7120925B2 (ja) 2022-08-17
ES2805026T3 (es) 2021-02-10
JP2019510793A (ja) 2019-04-18
AU2017245687B2 (en) 2023-03-09
CN116036117A (zh) 2023-05-02
CA3019981A1 (en) 2017-10-12
US20190119676A1 (en) 2019-04-25
CN109562188A (zh) 2019-04-02
EP3744350A1 (en) 2020-12-02
US20210079397A1 (en) 2021-03-18
PL3439703T3 (pl) 2020-10-19
EP3439703B1 (en) 2020-04-29
US10913945B2 (en) 2021-02-09
AU2017245687A1 (en) 2018-10-25
EP3439703A1 (en) 2019-02-13
DK3439703T3 (da) 2020-06-29
HUE049931T2 (hu) 2020-11-30
US11912993B2 (en) 2024-02-27
EP3228326A1 (en) 2017-10-11

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