CN109529015A - 一种女性hpv抗菌剂及其制备方法 - Google Patents
一种女性hpv抗菌剂及其制备方法 Download PDFInfo
- Publication number
- CN109529015A CN109529015A CN201811519546.2A CN201811519546A CN109529015A CN 109529015 A CN109529015 A CN 109529015A CN 201811519546 A CN201811519546 A CN 201811519546A CN 109529015 A CN109529015 A CN 109529015A
- Authority
- CN
- China
- Prior art keywords
- accounting
- motherwort
- turmeric
- glutathione
- kuh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003242 anti bacterial agent Substances 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims description 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 42
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims abstract description 28
- CHVZQMAANSUXJU-JJKGCWMISA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanamide;hydrochloride Chemical compound Cl.NC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO CHVZQMAANSUXJU-JJKGCWMISA-N 0.000 claims abstract description 14
- 241000193830 Bacillus <bacterium> Species 0.000 claims abstract description 14
- 244000157790 Buglossoides arvense Species 0.000 claims abstract description 14
- 235000004256 Buglossoides arvense Nutrition 0.000 claims abstract description 14
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 claims abstract description 14
- 244000163122 Curcuma domestica Species 0.000 claims abstract description 14
- 235000003392 Curcuma domestica Nutrition 0.000 claims abstract description 14
- 108010024636 Glutathione Proteins 0.000 claims abstract description 14
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 claims abstract description 14
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 14
- 235000003373 curcuma longa Nutrition 0.000 claims abstract description 14
- 229960003180 glutathione Drugs 0.000 claims abstract description 14
- 235000013976 turmeric Nutrition 0.000 claims abstract description 14
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 13
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 13
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 13
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 13
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000013717 Houttuynia Nutrition 0.000 claims abstract description 11
- 240000000691 Houttuynia cordata Species 0.000 claims abstract description 11
- 229960005323 phenoxyethanol Drugs 0.000 claims abstract description 11
- 238000000855 fermentation Methods 0.000 claims abstract description 10
- 230000004151 fermentation Effects 0.000 claims abstract description 10
- 238000004519 manufacturing process Methods 0.000 claims abstract 2
- 241000207925 Leonurus Species 0.000 claims description 12
- 239000003814 drug Substances 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 229940079593 drug Drugs 0.000 claims description 6
- 241000251468 Actinopterygii Species 0.000 claims description 3
- 244000025254 Cannabis sativa Species 0.000 claims description 3
- 241000270295 Serpentes Species 0.000 claims description 3
- YAVVGPBYBUYPSR-UHFFFAOYSA-N benzene;oxygen Chemical compound [O].C1=CC=CC=C1 YAVVGPBYBUYPSR-UHFFFAOYSA-N 0.000 claims description 3
- 239000008367 deionised water Substances 0.000 claims description 3
- 229910021641 deionized water Inorganic materials 0.000 claims description 3
- 238000004090 dissolution Methods 0.000 claims description 3
- 235000019441 ethanol Nutrition 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 235000020995 raw meat Nutrition 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 240000007890 Leonurus cardiaca Species 0.000 abstract 2
- 208000022361 Human papillomavirus infectious disease Diseases 0.000 description 20
- 239000000243 solution Substances 0.000 description 9
- 241000700605 Viruses Species 0.000 description 7
- 208000019065 cervical carcinoma Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 241000701806 Human papillomavirus Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 208000009608 Papillomavirus Infections Diseases 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 230000019522 cellular metabolic process Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 201000010153 skin papilloma Diseases 0.000 description 2
- 230000036548 skin texture Effects 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 230000002477 vacuolizing effect Effects 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 206010059313 Anogenital warts Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 241001631646 Papillomaviridae Species 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 201000004196 common wart Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 239000007938 effervescent tablet Substances 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 208000002672 hepatitis B Diseases 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 208000003154 papilloma Diseases 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 230000005582 sexual transmission Effects 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种女性HPV抗菌剂及其制造方法，包括以下成分：丙二醇、芽孢杆菌发酵产物、氨基葡萄糖盐酸盐、谷胱甘肽、苦参、黄柏、蛇床子、当归、姜黄、鱼腥草、益母草、山药、紫草、苯氧乙醇、水溶凉感剂HK8465和卡波U20，所述丙二醇占比为4%、所述芽孢杆菌发酵产物占比为1%、所述氨基葡萄糖盐酸盐占比为8.97%、所述谷胱甘肽占比为5%、所述苦参占比为15%、所述黄柏占比为10%、所述蛇床子占比为5%、所述当归占比为5%、所述姜黄占比为5%、所述鱼腥草占比为10%、所述益母草占比为15%、所述山药占比为5%、所述紫草占比为10%、所述苯氧乙醇占比为0.5%、所述水溶凉感剂HK8465占比为0.03%和所述卡波占U20比为0.5%。
Description
技术领域
本发明涉及医药技术领域，尤其是涉及一种女性HPV抗菌剂及其制备方法。
背景技术
人类乳头瘤病毒(Human Papilloma Virus，简称HPV)是一种嗜上皮性病毒，有高度的特异性，长期以来，已知HPV可引起人类良性的肿瘤和疣，如生长在生殖器官附近皮肤和粘膜上的人类寻常疣、尖锐湿疣以及生长在粘膜上的乳头状瘤。像乙肝病毒一样，HPV也是一种DNA病毒。它原是多瘤空泡病毒科的一员，1999年国际病毒分类委员会(ICTV)取消多瘤空泡病毒科，代之以乳头瘤病毒科，因此，HPV便归属此门下。HPV感染途径⒈性传播途径；⒉密切接触；⒊间接接触：通过接触感染者的衣物、生活用品、用具等；⒋医源性感染：医务人员在治疗护理时防护不好，造成自身感染或通过医务人员传给患者；⒌母婴传播：是由婴儿通过孕妇产道的密切接触；
75%的女人会在一生中感染过HPV病毒（人乳头瘤状病毒，99%的宫颈癌与其相关），但又有90%的女人会在1-2年内依靠自身免疫系统将HPV病毒清除出体外，只有极少数的“漏网之鱼”会发展为宫颈癌。目前，已知的HPV有100多种不同类型，其中大部分类型被视为“低风险”，与宫颈癌并无关联。但有14种HPV类型被列为“高风险”，并已经证实它们会导致几乎所有的宫颈癌；
目前针对HPV的治疗主要是通过手术、针剂注射和口服药物治疗，这些方法由于是西药，对于身体伤害副作用大，还有通过外用药物治疗，例如通过在病患处给药，常用的药物有栓剂，泡腾片等，但这些药物或多或少存在缺陷，作用较为单一。
发明内容
本发明要解决的技术问题是克服现有的缺陷，提供一种女性HPV抗菌剂及其制备方法，从而解决上述问题。
为实现上述目的，本发明提供如下技术方案一种女性HPV抗菌剂，包括以下成分：丙二醇、芽孢杆菌发酵产物、氨基葡萄糖盐酸盐、谷胱甘肽、苦参、黄柏、蛇床子、当归、姜黄、鱼腥草、益母草、山药、紫草、苯氧乙醇、水溶凉感剂HK8465和卡波U20，所述丙二醇占比为4%、所述芽孢杆菌发酵产物占比为1%、所述氨基葡萄糖盐酸盐占比为8.97%、所述谷胱甘肽占比为5%、所述苦参占比为15%、所述黄柏占比为10%、所述蛇床子占比为5%、所述当归占比为5%、所述姜黄占比为5%、所述鱼腥草占比为10%、所述益母草占比为15%、所述山药占比为5%、所述紫草占比为10%、所述苯氧乙醇占比为0.5%、所述水溶凉感剂HK8465占比为0.03%和所述卡波占U20比为0.5%。
本发明还提供一种女性HPV抗菌剂的制备方法，其特征在于，包括以下步骤；
步骤一；准备材料：按照比例准备：所述丙二醇占比为4%、所述芽孢杆菌发酵产物占比为1%、所述氨基葡萄糖盐酸盐占比为8.97%、所述谷胱甘肽占比为5%、所述苦参占比为15%、所述黄柏占比为10%、所述蛇床子占比为5%、所述当归占比为5%、所述姜黄占比为5%、所述鱼腥草占比为10%、所述益母草占比为15%、所述山药占比为5%、所述紫草占比为10%、所述苯氧乙醇占比为0.5%、所述水溶凉感剂HK8465占比为0.03%和所述卡波占U20比为0.5%；
步骤二：先添加按比例准备好的所述丙二醇、所述芽孢杆菌发酵产物，要先增容透明，增容透明了才加入去离子水；
步骤三；然后向步骤二中溶液内逐一添加氨基葡萄糖盐酸盐、谷胱甘肽、苦参、黄柏、蛇床子、当归、姜黄、鱼腥草、益母草、山药、紫草、苯氧乙醇、水溶凉感剂HK8465；
步骤四；最后在步骤三的溶液内添加卡波占U20，刚投入下去30分钟内不要搅拌，卡波散开溶解来再进行搅拌。
作为本发明一种女性HPV抗菌剂的制备方法的一种优选技术方案，溶液的PH值控制在6.5-7之间。
与现有技术相比，本发明的有益效果是：本发明立足于对HPV发病机理和治疗原理，配伍合理、科学，经大量临床验证，无毒无副作用，本发明的产品涂于患处以后，能迅速扩散至不适处，深入肌理，通过药物组合发挥的药效促进细胞新陈代谢，从而增强细胞对药物的吸收能力，在皮肤表面形成一层薄膜，有效阻绝外来细菌的侵入，并快速修复皮肤组织，提高创口愈合再生能力，该凝胶中的多种植物提取物还能够提高机体免疫力，能起到良好的抗病毒效果。
具体实施方式
对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例，基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
本发明提供一种技术方案：一种女性HPV抗菌剂，包括以下成分：丙二醇、芽孢杆菌发酵产物、氨基葡萄糖盐酸盐、谷胱甘肽、苦参、黄柏、蛇床子、当归、姜黄、鱼腥草、益母草、山药、紫草、苯氧乙醇、水溶凉感剂HK8465和卡波U20，所述丙二醇占比为4%、所述芽孢杆菌发酵产物占比为1%、所述氨基葡萄糖盐酸盐占比为8.97%、所述谷胱甘肽占比为5%、所述苦参占比为15%、所述黄柏占比为10%、所述蛇床子占比为5%、所述当归占比为5%、所述姜黄占比为5%、所述鱼腥草占比为10%、所述益母草占比为15%、所述山药占比为5%、所述紫草占比为10%、所述苯氧乙醇占比为0.5%、所述水溶凉感剂HK8465占比为0.03%和所述卡波占U20比为0.5%。
本发明还提供一种女性HPV抗菌剂的制备方法，其特征在于，包括以下步骤；
步骤一；准备材料：按照比例准备：所述丙二醇占比为4%、所述芽孢杆菌发酵产物占比为1%、所述氨基葡萄糖盐酸盐占比为8.97%、所述谷胱甘肽占比为5%、所述苦参占比为15%、所述黄柏占比为10%、所述蛇床子占比为5%、所述当归占比为5%、所述姜黄占比为5%、所述鱼腥草占比为10%、所述益母草占比为15%、所述山药占比为5%、所述紫草占比为10%、所述苯氧乙醇占比为0.5%、所述水溶凉感剂HK8465占比为0.03%和所述卡波占U20比为0.5%；
步骤二：先添加按比例准备好的所述丙二醇、所述芽孢杆菌发酵产物，要先增容透明，增容透明了才加入去离子水；
步骤三；然后向步骤二中溶液内逐一添加氨基葡萄糖盐酸盐、谷胱甘肽、苦参、黄柏、蛇床子、当归、姜黄、鱼腥草、益母草、山药、紫草、苯氧乙醇、水溶凉感剂HK8465；
步骤四；最后在步骤三的溶液内添加卡波占U20，刚投入下去30分钟内不要搅拌，卡波散开溶解来再进行搅拌。
作为本发明一种女性HPV抗菌剂的制备方法的一种优选技术方案，溶液的PH值控制在6.5-7之间。
本发明立足于对HPV发病机理和治疗原理，配伍合理、科学，经大量临床验证，无毒无副作用，本发明的产品涂于患处以后，能迅速扩散至不适处，深入肌理，通过药物组合发挥的药效促进细胞新陈代谢，从而增强细胞对药物的吸收能力，在皮肤表面形成一层薄膜，有效阻绝外来细菌的侵入，并快速修复皮肤组织，提高创口愈合再生能力，该凝胶中的多种植物提取物还能够提高机体免疫力，能起到良好的抗病毒效果。
最后应说明的是：以上所述仅为本发明的优选实施例而已，并不用于限制本发明，尽管参照前述实施例对本发明进行了详细的说明，对于本领域的技术人员来说，其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换,凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (3)
1.一种女性HPV抗菌剂及其制造方法，其特征在于，包括以下成分：丙二醇、芽孢杆菌发酵产物、氨基葡萄糖盐酸盐、谷胱甘肽、苦参、黄柏、蛇床子、当归、姜黄、鱼腥草、益母草、山药、紫草、苯氧乙醇、水溶凉感剂HK8465和卡波U20，所述丙二醇占比为4%、所述芽孢杆菌发酵产物占比为1%、所述氨基葡萄糖盐酸盐占比为8.97%、所述谷胱甘肽占比为5%、所述苦参占比为15%、所述黄柏占比为10%、所述蛇床子占比为5%、所述当归占比为5%、所述姜黄占比为5%、所述鱼腥草占比为10%、所述益母草占比为15%、所述山药占比为5%、所述紫草占比为10%、所述苯氧乙醇占比为0.5%、所述水溶凉感剂HK8465占比为0.03%和所述卡波占U20比为0.5%。
2.一种女性HPV抗菌剂的制备方法，其特征在于，包括以下步骤；
步骤一；准备材料：按照比例准备：所述丙二醇占比为4%、所述芽孢杆菌发酵产物占比为1%、所述氨基葡萄糖盐酸盐占比为8.97%、所述谷胱甘肽占比为5%、所述苦参占比为15%、所述黄柏占比为10%、所述蛇床子占比为5%、所述当归占比为5%、所述姜黄占比为5%、所述鱼腥草占比为10%、所述益母草占比为15%、所述山药占比为5%、所述紫草占比为10%、所述苯氧乙醇占比为0.5%、所述水溶凉感剂HK8465占比为0.03%和所述卡波占U20比为0.5%；
步骤二：先添加按比例准备好的所述丙二醇、所述芽孢杆菌发酵产物，要先增容透明，增容透明了才加入去离子水；
步骤三；然后向步骤二中溶液内逐一添加氨基葡萄糖盐酸盐、谷胱甘肽、苦参、黄柏、蛇床子、当归、姜黄、鱼腥草、益母草、山药、紫草、苯氧乙醇、水溶凉感剂HK8465；
步骤四；最后在步骤三的溶液内添加卡波占U20，刚投入下去30分钟内不要搅拌，卡波散开溶解来再进行搅拌。
3.根据权利要求2所述的一种女性HPV抗菌剂的制备方法，其特征在于，溶液的PH值控制在6.5-7之间。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811519546.2A CN109529015A (zh) | 2018-12-12 | 2018-12-12 | 一种女性hpv抗菌剂及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811519546.2A CN109529015A (zh) | 2018-12-12 | 2018-12-12 | 一种女性hpv抗菌剂及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109529015A true CN109529015A (zh) | 2019-03-29 |
Family
ID=65854589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811519546.2A Pending CN109529015A (zh) | 2018-12-12 | 2018-12-12 | 一种女性hpv抗菌剂及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109529015A (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110179839A (zh) * | 2019-07-03 | 2019-08-30 | 上海美哈医药科技有限公司 | 一种抗肌瘤凝胶剂及其制备方法 |
| CN110179840A (zh) * | 2019-07-03 | 2019-08-30 | 上海美哈医药科技有限公司 | 一种冬虫夏草阴道抗免疫抑菌剂及其制备方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104225015A (zh) * | 2014-10-09 | 2014-12-24 | 无限极（中国）有限公司 | 一种女性护理用中药组合物及其应用 |
| CN106729227A (zh) * | 2017-01-18 | 2017-05-31 | 张勇 | 一种治疗hpv感染宫颈癌的纯中药凝胶及其制备方法 |
| CN107137576A (zh) * | 2017-04-18 | 2017-09-08 | 陕西萃生医疗科技有限公司 | 一种防治人乳头瘤病毒感染的药物制剂及其制备方法 |
| CN108721449A (zh) * | 2018-07-30 | 2018-11-02 | 西安万和医药科技有限公司 | 一种用于抑制hpv感染，有效增强抗hpv感染的凝胶 |
-
2018
- 2018-12-12 CN CN201811519546.2A patent/CN109529015A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104225015A (zh) * | 2014-10-09 | 2014-12-24 | 无限极（中国）有限公司 | 一种女性护理用中药组合物及其应用 |
| CN106729227A (zh) * | 2017-01-18 | 2017-05-31 | 张勇 | 一种治疗hpv感染宫颈癌的纯中药凝胶及其制备方法 |
| CN107137576A (zh) * | 2017-04-18 | 2017-09-08 | 陕西萃生医疗科技有限公司 | 一种防治人乳头瘤病毒感染的药物制剂及其制备方法 |
| CN108721449A (zh) * | 2018-07-30 | 2018-11-02 | 西安万和医药科技有限公司 | 一种用于抑制hpv感染，有效增强抗hpv感染的凝胶 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110179839A (zh) * | 2019-07-03 | 2019-08-30 | 上海美哈医药科技有限公司 | 一种抗肌瘤凝胶剂及其制备方法 |
| CN110179840A (zh) * | 2019-07-03 | 2019-08-30 | 上海美哈医药科技有限公司 | 一种冬虫夏草阴道抗免疫抑菌剂及其制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109529015A (zh) | 一种女性hpv抗菌剂及其制备方法 | |
| CN111297961A (zh) | 一种促进伤口愈合的侗药 | |
| CN106309577A (zh) | 一种用于治疗鼻炎的抑菌膏及其制备方法 | |
| CN101439114B (zh) | 一种治疗烧烫伤的中药及其制备方法 | |
| CN103446227A (zh) | 一种治疗慢性前列腺炎的中药 | |
| CN104587033B (zh) | 一种纳米银鼻炎膏 | |
| CN106421590A (zh) | 一种用于治疗色斑的药物制剂及其用途 | |
| CN110393768A (zh) | 一种母猪子宫消炎的组合中药灌注药物及其制备方法和应用 | |
| CN102805800B (zh) | 一种治疗神经性皮炎的中药组合物 | |
| CN115463200A (zh) | 一种治疗腺样体肥大的中药组合物、贴剂及其制备方法 | |
| CN108938703A (zh) | 快速抗菌的妇科凝胶 | |
| CN108403570A (zh) | 对湿疹引起的皮肤瘙痒有改善效果的体用凝露及制备方法 | |
| CN101337008B (zh) | 治疗急性乳腺炎的外用药物及其制备方法 | |
| CN114306526A (zh) | 一种复方苦丁茶中药提取物及其在制备沐浴露或洗手液中的应用 | |
| CN107213261A (zh) | 有机硒组合物、其制备方法及其用途 | |
| CN106727893A (zh) | 用于放射性口炎的药物组合物及其制备方法 | |
| CN112156225A (zh) | 一种壳聚糖或和海藻多糖复合生物基质液体敷料凝胶制剂及其制备方法 | |
| CN105435048A (zh) | 一种治疗甲状腺肿瘤的中药 | |
| CN108721381A (zh) | 一种治食道癌的配方 | |
| CN104784311B (zh) | 用于防治动物口疮蹄癀的组合药物及其制备方法 | |
| CN116077582A (zh) | 一种用于面瘫治疗的中药制剂及其制备方法和应用 | |
| CN104623420B (zh) | 一种治疗扁平疣的中药软膏 | |
| CN104721424B (zh) | 一种治疗痰火壅结型耳鸣的中药 | |
| CN104922463B (zh) | 一种治疗小儿风热犯表型水痘的中药膏及其制备方法 | |
| CN102068471B (zh) | 一种治疗搭背类疾病的外用药 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190329 |
|
| WD01 | Invention patent application deemed withdrawn after publication |