CN109528622A - A kind of anti-acne repairs essence and preparation method thereof - Google Patents

A kind of anti-acne repairs essence and preparation method thereof Download PDF

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Publication number
CN109528622A
CN109528622A CN201811616891.8A CN201811616891A CN109528622A CN 109528622 A CN109528622 A CN 109528622A CN 201811616891 A CN201811616891 A CN 201811616891A CN 109528622 A CN109528622 A CN 109528622A
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Prior art keywords
acne
extract
herba dendrobii
essence
proline
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CN201811616891.8A
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杨鹏
黄伟
欧阳陈
胡晓莉
王乐平
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Yingteli (guangzhou) Biotechnology Co Ltd
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Yingteli (guangzhou) Biotechnology Co Ltd
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Priority to CN201811616891.8A priority Critical patent/CN109528622A/en
Publication of CN109528622A publication Critical patent/CN109528622A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48Thickener, Thickening system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Pharmacology & Pharmacy (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to cosmetic fields, it in particular discloses a kind of anti-acne and repairs essence and preparation method thereof, now propose following scheme, raw material including following weight percent: gold fork Herba Dendrobii extract 0.5-1%, dendrobium candidum extract 0.5-1%, matrine 0.8-1.2%, bright string coccus/radish root tunning filtrate 3-4%, transdermal EGF 0.0003-0.0008%, glycerol 5-10%, proline 5-10%, polypropylene acyl group dimethyltaurine ammonium 0.2-0.5%, Sodium Hyaluronate 0.05-0.1%, surplus is deionized water, gold is pitched into Herba Dendrobii extract, transdermal EGF sequentially adds emulsion pot, it is evenly stirred until that product is transparent.Anti-acne of the invention is repaired essence and is made of the plant extracts with acne-removing, does not stimulate naturally, and safe and efficient antibacterial anti-inflammatory soothes the skin redness, has and smooths acne hole, reduce acne print, inhibits the regenerated effect of small pox.

Description

A kind of anti-acne repairs essence and preparation method thereof
Technical field
The present invention relates to cosmetic technical fields more particularly to a kind of anti-acne to repair essence and preparation method thereof.
Background technique
Small pox, scientific name acne are the sebaceous glands excessive secretion grease since 3male hormone secretion is vigorous, hair follicle and sebaceous glands Pipe obstruction, a kind of scytitis that inflammation causes.Skin type, the lack of standardization, pressure of diet work and rest, bad environments may all be led Small pox is caused to generate.
Currently, the product for resolving poxes for being used in a manner of smearing in cosmetics, mainly has with salicylic acid composite bactericide The product of Western medicine mode and has effects that similar Chinese medicine and plant extract with Cortex Phellodendri bark extract, black extract of willow bark etc. The product of object compounding mode.The former is quick, but irritation is strong, side effect is big, the mild safety of the latter, but slow effect, when effect Between it is long, be both difficult to realize mild efficiently anti-acne and repair the double effects of impaired skin.Therefore, it is necessary to research and develop a kind of temperature Economic benefits and social benefits unification, while the essence that skin sense is salubrious are repaired with efficient, anti-acne.
Chinese patent application CN 104188849A discloses a kind of containing purslane extract, white willow bark extract Removing acnes and controlling oil composition.Chinese patent CN 105012479B disclose it is a kind of containing Butyrospermum parkii fruit rouge, it is phellodendron extract, black Extract of willow bark, purslane extract, extractive of perilla, Gotu Kola P.E and Semen phaseoli radiati extract acne-removing composition and its Applied to the Whelk-eliminating paste containing the acne-removing composition.It being described according to patent, effect is concentrated mainly on anti-acne and inhibits small pox regeneration, Smooth acne hole, desalination acne print in terms of, through retrieving, at present it is not yet found that include gold fork Herba Dendrobii extract, dendrobium candidum extract, Have both anti-acne while the ingredients such as matrine, bright string coccus/radish root tunning filtrate, transdermal EGF and reparation skin is dual The essence class product of effect.
For this purpose, the present invention proposes that a kind of anti-acne repairs essence and preparation method thereof.
Summary of the invention
The purpose of the present invention is to solve disadvantage existing in the prior art, and a kind of anti-acne proposed repair essence and Preparation method.
To achieve the goals above, present invention employs following technical solutions:
A kind of anti-acne reparation essence, the raw material including following weight percent: gold fork Herba Dendrobii extract 0.5-1%, dendrobium candidum mention Take object 0.5-1%, matrine 0.8-1.2%, bright string coccus/radish root tunning filtrate 3-4%, transdermal EGF 0.0003- 0.0008%, glycerol 5-10%, proline 5-10%, polypropylene acyl group dimethyltaurine ammonium 0.2-0.5%, Sodium Hyaluronate 0.05-0.1%, surplus are deionized water.
Preferably, the raw material including following weight percent: gold fork Herba Dendrobii extract 1%, dendrobium candidum extract 1%, hardship Join alkali 1%, bright string coccus/radish root tunning filtrate 3.5%, transdermal EGF 0.0006%, glycerol 5%, proline 5%, polypropylene Acyl group dimethyltaurine ammonium 0.3%, Sodium Hyaluronate 0.06%, surplus are deionized water.
Preferably, the weight ratio of the gold fork Herba Dendrobii extract and dendrobium candidum extract is 1:1.
Preferably, the weight ratio of the glycerol and proline is 1:1.
A kind of anti-acne repairs the preparation method of essence, includes the following steps,
S1 adds the deionized water of above-mentioned specific gravity, glycerol, proline, polypropylene acyl group dimethyltaurine ammonium, Sodium Hyaluronate Enter emulsion pot, be stirred and heated to 80-85 DEG C, mixing speed is 40-50 revs/min, insulated and stirred 30-40 minutes, cools to 45 ℃;
S2, by gold fork Herba Dendrobii extract, dendrobium candidum extract, matrine, bright string coccus/radish root tunning filtrate, saturating Skin EGF sequentially adds emulsion pot, is evenly stirred until that product is transparent.
Compared with prior art, the beneficial effects of the present invention are:
1, anti-acne of the invention is repaired essence and is made of the plant extracts with acne-removing, does not stimulate naturally, safe and efficient Antibacterial anti-inflammatory soothes the skin redness, has and smooths acne hole, reduce acne print, inhibits the regenerated effect of small pox.
2, anti-acne of the invention repairs essence, has the transdermal EGF made from biological method, can promote cell Proliferation, Accelerate skin metabolism, has effects that actively to repair impaired skin.
3, anti-acne of the invention repairs essence, is free of preservative, is sent out using bright string coccus made from biofermentation/radish root Ferment Product filtrate is formulated milder, while having anti-inflammatory effect of releiving.Essence is made using polypropylene acyl group dimethyltaurine ammonium For thickener, formulation stable, irritation is low, and skin sense is very salubrious, is beneficial to functional component and plays a role.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.
Embodiment one
A kind of anti-acne proposed by the present invention repairs essence, the raw material including following weight percent: gold fork Herba Dendrobii extract 0.5%, Dendrobium candidum extract 0.5%, matrine 0.8%, bright string coccus/radish root tunning filtrate 3%, transdermal EGF 0.0003%, Glycerol 5%, proline 5%, polypropylene acyl group dimethyltaurine ammonium 0.2%, Sodium Hyaluronate 0.05%, surplus are deionized water.
A kind of anti-acne proposed by the present invention repairs the preparation method of essence, includes the following steps,
S1 adds the deionized water of above-mentioned specific gravity, glycerol, proline, polypropylene acyl group dimethyltaurine ammonium, Sodium Hyaluronate Enter emulsion pot, be stirred and heated to 80-85 DEG C, mixing speed is 40-50 revs/min, insulated and stirred 30-40 minutes, cools to 45 ℃;
S2, by gold fork Herba Dendrobii extract, dendrobium candidum extract, matrine, bright string coccus/radish root tunning filtrate, saturating Skin EGF sequentially adds emulsion pot, is evenly stirred until that product is transparent.
Embodiment two
A kind of anti-acne proposed by the present invention repairs essence, the raw material including following weight percent: gold fork Herba Dendrobii extract 1%, iron Skin Herba Dendrobii extract 1%, matrine 1.2%, bright string coccus/radish root tunning filtrate 4%, transdermal EGF 0.0008%, glycerol 10%, proline 10%, polypropylene acyl group dimethyltaurine ammonium 0.5%, Sodium Hyaluronate 0.1%, surplus are deionized water.
A kind of anti-acne proposed by the present invention repairs the preparation method of essence, includes the following steps,
S1 adds the deionized water of above-mentioned specific gravity, glycerol, proline, polypropylene acyl group dimethyltaurine ammonium, Sodium Hyaluronate Enter emulsion pot, be stirred and heated to 80-85 DEG C, mixing speed is 40-50 revs/min, insulated and stirred 30-40 minutes, cools to 45 ℃。
S2 filters gold fork Herba Dendrobii extract, dendrobium candidum extract, matrine, bright string coccus/radish root tunning Liquid, transdermal EGF sequentially add emulsion pot, are evenly stirred until that product is transparent.
Embodiment three
A kind of anti-acne proposed by the present invention repairs essence, the raw material including following weight percent: gold fork Herba Dendrobii extract 1%, iron Skin Herba Dendrobii extract 1%, matrine 1%, bright string coccus/radish root tunning filtrate 3.5%, transdermal EGF 0.0006%, glycerol 5%, proline 5%, polypropylene acyl group dimethyltaurine ammonium 0.3%, Sodium Hyaluronate 0.06%, surplus are deionized water.
A kind of anti-acne proposed by the present invention repairs the preparation method of essence, includes the following steps,
S1 adds the deionized water of above-mentioned specific gravity, glycerol, proline, polypropylene acyl group dimethyltaurine ammonium, Sodium Hyaluronate Enter emulsion pot, be stirred and heated to 80-85 DEG C, mixing speed is 40-50 revs/min, insulated and stirred 30-40 minutes, cools to 45 ℃。
S2 filters gold fork Herba Dendrobii extract, dendrobium candidum extract, matrine, bright string coccus/radish root tunning Liquid, transdermal EGF sequentially add emulsion pot, are evenly stirred until that product is transparent.
Comparative example
The embodiment 1 of Chinese patent CN 105012479B.
Product evaluation:
Test crowd: selecting 30 20-45 years old triers, and face has apparent acne and small pox, no skin allergy history.As this The test crowd of invention.
Test method: taking appropriate given the test agent to be coated in affected part easy to clean, 2 times a day, each 1 time sooner or later, uses 2 weeks.By Examination person keeps good daily life system time and eating habit during use.The feedback result of subject is counted after 7 days, it is specific to tie Fruit see the table below.
Compared with prior art, the beneficial effects of the present invention are:
1, anti-acne of the invention is repaired essence and is made of the plant extracts with acne-removing, does not stimulate naturally, safe and efficient Antibacterial anti-inflammatory soothes the skin redness, has and smooths acne hole, reduce acne print, inhibits the regenerated effect of small pox.
2, anti-acne of the invention repairs essence, has the transdermal EGF made from biological method, can promote cell Proliferation, Accelerate skin metabolism, has effects that actively to repair impaired skin.
3, anti-acne of the invention repairs essence, is free of preservative, is sent out using bright string coccus made from biofermentation/radish root Ferment Product filtrate is formulated milder, while having anti-inflammatory effect of releiving.Essence is made using polypropylene acyl group dimethyltaurine ammonium For thickener, formulation stable, irritation is low, and skin sense is very salubrious, is beneficial to functional component and plays a role.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (5)

1. a kind of anti-acne repairs essence, which is characterized in that the raw material including following weight percent: gold fork Herba Dendrobii extract 0.5- 1%, dendrobium candidum extract 0.5-1%, matrine 0.8-1.2%, bright string coccus/radish root tunning filtrate 3-4%, transdermal EGF 0.0003-0.0008%, glycerol 5-10%, proline 5-10%, polypropylene acyl group dimethyltaurine ammonium 0.2-0.5%, thoroughly Bright matter acid sodium 0.05-0.1%, surplus are deionized water.
2. a kind of anti-acne according to claim 1 repairs essence, which is characterized in that the original including following weight percent Material: gold fork Herba Dendrobii extract 1%, dendrobium candidum extract 1%, matrine 1%, bright string coccus/radish root tunning filtrate 3.5%, transdermal EGF 0.0006%, glycerol 5%, proline 5%, polypropylene acyl group dimethyltaurine ammonium 0.3%, Sodium Hyaluronate 0.06%, surplus is deionized water.
3. a kind of anti-acne according to claim 1 repairs essence, which is characterized in that the gold fork Herba Dendrobii extract and iron sheet The weight ratio of Herba Dendrobii extract is 1:1.
4. a kind of anti-acne according to claim 1 repairs essence, which is characterized in that the weight ratio of the glycerol and proline For 1:1.
5. the preparation method that a kind of anti-acne described in claim 1 repairs essence, which is characterized in that include the following steps,
S1 adds the deionized water of above-mentioned specific gravity, glycerol, proline, polypropylene acyl group dimethyltaurine ammonium, Sodium Hyaluronate Enter emulsion pot, be stirred and heated to 80-85 DEG C, mixing speed is 40-50 revs/min, insulated and stirred 30-40 minutes, cools to 45 ℃;
S2, by gold fork Herba Dendrobii extract, dendrobium candidum extract, matrine, bright string coccus/radish root tunning filtrate, saturating Skin EGF sequentially adds emulsion pot, is evenly stirred until that product is transparent.
CN201811616891.8A 2018-12-28 2018-12-28 A kind of anti-acne repairs essence and preparation method thereof Pending CN109528622A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514053A (en) * 2019-11-06 2020-08-11 广州妮趣化妆品有限公司 Composition with acne removing effect and preparation method and application thereof
WO2021232334A1 (en) * 2020-05-21 2021-11-25 极臣生物科技(深圳)有限公司 Traditional chinese medicine composition having anti-acne effect, preparation method therefor, and use thereof
CN114432211A (en) * 2020-11-03 2022-05-06 广州樱奈儿化妆品有限公司 Dendrobium acne removing and repairing cream and preparation method thereof
CN115124804A (en) * 2021-03-29 2022-09-30 上普博源(北京)生物科技有限公司 Composition for treating skin inflammation
CN117323271A (en) * 2023-12-01 2024-01-02 广州百孚润化工有限公司 Acne-removing composition, and preparation method and application thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514053A (en) * 2019-11-06 2020-08-11 广州妮趣化妆品有限公司 Composition with acne removing effect and preparation method and application thereof
CN111514053B (en) * 2019-11-06 2023-02-07 广州妮趣化妆品有限公司 Composition with acne removing effect and preparation method and application thereof
WO2021232334A1 (en) * 2020-05-21 2021-11-25 极臣生物科技(深圳)有限公司 Traditional chinese medicine composition having anti-acne effect, preparation method therefor, and use thereof
CN114432211A (en) * 2020-11-03 2022-05-06 广州樱奈儿化妆品有限公司 Dendrobium acne removing and repairing cream and preparation method thereof
CN115124804A (en) * 2021-03-29 2022-09-30 上普博源(北京)生物科技有限公司 Composition for treating skin inflammation
CN115124804B (en) * 2021-03-29 2023-10-31 上普博源(北京)生物科技有限公司 a composition
CN117323271A (en) * 2023-12-01 2024-01-02 广州百孚润化工有限公司 Acne-removing composition, and preparation method and application thereof
CN117323271B (en) * 2023-12-01 2024-01-26 广州百孚润化工有限公司 Acne-removing composition, and preparation method and application thereof

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Application publication date: 20190329

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