CN109526944A - A kind of exhaust bubble structure in Perfused isolated heart system - Google Patents
A kind of exhaust bubble structure in Perfused isolated heart system Download PDFInfo
- Publication number
- CN109526944A CN109526944A CN201910012888.3A CN201910012888A CN109526944A CN 109526944 A CN109526944 A CN 109526944A CN 201910012888 A CN201910012888 A CN 201910012888A CN 109526944 A CN109526944 A CN 109526944A
- Authority
- CN
- China
- Prior art keywords
- threeway
- rule
- heat insulation
- insulation tank
- snakelike
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000009413 insulation Methods 0.000 claims abstract description 32
- 238000009434 installation Methods 0.000 claims abstract description 17
- 239000007921 spray Substances 0.000 claims abstract description 9
- 239000007788 liquid Substances 0.000 claims description 19
- 239000003814 drug Substances 0.000 claims description 15
- 239000012530 fluid Substances 0.000 claims description 14
- 238000004321 preservation Methods 0.000 claims description 8
- 230000002459 sustained effect Effects 0.000 claims description 5
- 238000000034 method Methods 0.000 description 4
- 230000010412 perfusion Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000270295 Serpentes Species 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000010247 heart contraction Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
Abstract
The present invention relates to Perfused isolated heart fields, specifically, the exhaust bubble structure being related in a kind of Perfused isolated heart system, including installation base plate, heat insulation tank, two overflow cups and two snakelike heaters, each snakelike heater is connected to the first port of Rule threeway below one, the second port of two Rule threeways one is connected to two ports of Rule threeway two respectively, the third port of Rule threeway two and the top of heat insulation tank connect, T-type threeway there are two being also set up on installation base plate corresponding with Rule threeway one, two T-type threeways are connected with the third port of corresponding Rule threeway one respectively, the upper end of each T-type threeway is connected with corresponding overflow cup, the lower end of each T-type threeway is respectively connected with a spray pump, the present invention predominantly provides great convenience in operation exhaust bubble.
Description
Technical field
The present invention relates to Perfused isolated heart fields, and in particular, to the exhaust bubble in a kind of Perfused isolated heart system
Structure.
Background technique
Perfused isolated heart device is an important device for carrying out Perfused isolated heart, and Perfused isolated heart is by heart
It taking out, is continuously injected into perfusate appropriate, perfusate must be able to replace blood, so that the animation of isolated heart is kept,
In experiment keep in mind it is dirty before have to the discharge of bubble in pipeline to perfusion, if be not discharged, in perfusing course
Bubble in pipeline is possibly into arriving cardiovascular, and since air has a compressibility, when heart contraction, intravascular pressure increases,
Blood flow should be pushed, but because air has compressibility, air is compressed by, and the medical fluid before air does not just flow forward
, therefore medical fluid is caused to recycle, consequence as one can imagine, therefore being vented bubble process is the important step and base of an experiment
This.Equipment on the market all exists in the discharge process of bubble mostly and has very big difficulty and inconvenience.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides the exhaust bubble structure in a kind of Perfused isolated heart system, this knot
Structure predominantly provides great convenience in operation exhaust bubble.
Exhaust bubble structure in a kind of Perfused isolated heart system disclosed by the invention, including installation base plate, heat insulation tank, two
A overflow cup and two snakelike heaters, the state setting in a vertical shape of installation base plate, heat insulation tank and two snakelike heaters, two
Snakelike heater and heat insulation tank are arranged at the same side of installation base plate, and two snakelike heaters are in sustained height and are arranged, and two
The other side of installation base plate is arranged in a overflow cup, and two overflow cups are in sustained height setting, and heat insulation tank is arranged in two snakes
The underface in shape heater middle position, each snakelike heater are connected to the first port of Rule threeway below one, and two
The second port of Rule threeway one is connected to two ports of Rule threeway two respectively, the third port and heat preservation of Rule threeway two
The top of tank connects, and is also set up on installation base plate corresponding with Rule threeway one there are two T-type threeway, two T-type threeways are distinguished
It is connected with the third port of corresponding Rule threeway one, the upper end of each T-type threeway is connected with corresponding overflow cup, each T
The lower end of type threeway is respectively connected with a spray pump.
Preferably, helix tube is equipped in heat insulation tank, the outside upper and lower side of heat insulation tank is in be horizontally disposed with to have medical fluid entrance respectively
And medicine liquid outlet, medicine company entrance and medicine liquid outlet are connect with the upper and lower side of helix tube respectively, and needle is connected with below medicine liquid outlet
Head.
Preferably, the outside upper and lower side of heat insulation tank is respectively arranged with heat preservation outlet and the heat preservation entrance of internal connection.
Preferably, between snakelike heater and Rule threeway one, between heat insulation tank and Rule threeway two, Rule threeway one with
Between Rule threeway two, between overflow cup and T-type threeway, between Rule threeway one and T-type threeway, between heat insulation tank and syringe needle
Pass through piping connection.
Preferably, pipeline is identical as the diameter of helix tube and is 3 ~ 4mm.
The utility model has the advantages that the principle of the present invention is the pressure for being greater than top according to the pressure of lower end, so as to cause liquid to
Upper flowing, gas is lighter than liquid, to take bubble out of, which not only plays the function of heating again to not used liquid,
And medical fluid enters and exits that the horizontal saliva of mouth is flat, and internal helix tube caliber is uniform in size, has reached discharge bubble and goes downstream and has more held
Easily.
Detailed description of the invention
The drawings described herein are used to provide a further understanding of the present application, constitutes part of this application, this Shen
Illustrative embodiments and their description please are not constituted an undue limitation on the present application for explaining the application.In the accompanying drawings:
Fig. 1 is main view of the invention;
Fig. 2 is left view of the invention;
Fig. 3 is right view of the invention;
Fig. 4 is the structure chart of heat insulation tank;
Description of symbols: 1- Rule threeway one, 2-T type threeway, the snakelike heater of 3-, 4- heat insulation tank, 5- helix tube, 6- medical fluid
Entrance, 7- medicine liquid outlet, 8- keep the temperature entrance, 9- heat preservation outlet, 10- Rule threeway two.
Specific embodiment
Multiple embodiments of the invention will be disclosed with schema below, as clearly stated, the details in many practices
It will be explained in the following description.It should be appreciated, however, that the details in these practices is not applied to limit the present invention.Also
It is to say, in some embodiments of the invention, the details in these practices is non-essential.In addition, for the sake of simplifying schema,
Some known usual structures and component will be painted it in the drawings in simply illustrative mode.
In addition, the description for being such as related to " first ", " second " in the present invention is used for description purposes only, not especially censure
The meaning of order or cis-position, also non-to limit the present invention, the component described just for the sake of difference with same technique term
Or operation, it is not understood to indicate or imply its relative importance or implicitly indicates the number of indicated technical characteristic
Amount." first " is defined as a result, the feature of " second " can explicitly or implicitly include at least one of the features.In addition, each
Technical solution between a embodiment can be combined with each other, but must can be implemented as base with those of ordinary skill in the art
Plinth will be understood that the combination of this technical solution is not present when conflicting or cannot achieve when occurs in the combination of technical solution,
Also not the present invention claims protection scope within.
The exhaust bubble structure in a kind of Perfused isolated heart system referring to figs. 1 to 4, including installation base plate, guarantor
4, two overflow cups of warm tank and two snakelike heaters 3, installation base plate, heat insulation tank 4 and two snakelike heaters 3 are in a vertical shape
State setting, two snakelike heaters 3 and heat insulation tank 4 are arranged at the same side of installation base plate, and two snakelike heaters 3 are in same
One height is arranged, and the other side of installation base plate is arranged in two overflow cups, and two overflow cups are in sustained height setting, heat insulation tank
4 are arranged in the underface in two snakelike 3 middle positions of heater, and the of each snakelike heater 3 and Rule threeway below 1
Single port connection, the second port of two Rule threeways 1 are connected to two ports of Rule threeway 2 10 respectively, Rule threeway
2 10 third port is connect with the top of heat insulation tank 4, is also set up on installation base plate corresponding with Rule threeway 1 there are two T
Type threeway 2, two T-type threeways 2 are connected with the third port of corresponding Rule threeway 1 respectively, the upper end of each T-type threeway 2
It is connected with corresponding overflow cup, the lower end of each T-type threeway 2 is respectively connected with a spray pump.
Helix tube 5 is equipped in heat insulation tank 4, the outside upper and lower side of heat insulation tank 4 is in be horizontally disposed with to have medical fluid entrance 6 and medicine respectively
Liquid outlet 7, medicine company entrance and medicine liquid outlet 7 are connect with the upper and lower side of helix tube 5 respectively, and the lower section of medicine liquid outlet 7 is connected with needle
Head.
The outside upper and lower side of heat insulation tank 4 is respectively arranged with heat preservation outlet 9 and the heat preservation entrance 8 of internal connection.
Between snakelike heater 3 and Rule threeway 1, between heat insulation tank 4 and Rule threeway 21, Rule threeway 1 and Shandong
Between your threeway 2 10, between overflow cup and T-type threeway 2, between Rule threeway 1 and T-type threeway 2, heat insulation tank 4 and syringe needle it
Between pass through piping connection.
Pipeline is identical as the diameter of helix tube 5 and is 3 ~ 4mm.
If two T-type threeway 2 upper, middle and lower three interface code names are respectively B1/B2, C1/C2, A1/A2, two Rule three
Pipeline code name between logical 1 and heat insulation tank 4 is E and D, and the pipeline code name between E, D and medical fluid entrance 6 is F, medicine liquid outlet 7
Pipeline code name between syringe needle is G, and the code name of two spray pumps is a and b.
Working principle: being respectively provided with different perfusion solutions in two overflow cups (opening, medical fluid face leads to atmosphere), the first
Perfusion solution is got medical fluid by spray pump a and is entered from A1 mouthfuls, by T-type threeway 2, enters overflowing for the first via by B1 all the way
Flow cup, another way enters Rule threeway 1 by C1, when the direction of Rule threeway 1 is upward, adds since A1-C1- is snakelike
The pressure of hot device 3 be provided by spray pump, and from overflow cup to the pressure of snakelike heater 3 be by water gravity provide, upwards
Pressure be greater than downward pressure, so entire liquid flows from the bottom up, therefore can be by the snakelike heater 3 of the first via
In bubble through row upwards discharge, reach self-bleeding effect;Second of perfusion solution gets medical fluid from A2 by spray pump b
Mouth enters, and by T-type threeway 2, enters the overflow cup on the second tunnel by B2 all the way, another way enters Rule threeway by C2
1, when the direction of Rule threeway 1 is upward, due to the pressure of the snakelike heater 3 of A2-C2- be provided by spray pump, and from
The pressure of overflow cup to snakelike heater 3 is provided by the gravity of water, and upward pressure has been greater than downward pressure, so entirely
Liquid flows from the bottom up, therefore can reach automatic row by the bubble in the snakelike heater 3 on the second tunnel through row discharge upwards
The effect of gas;Most latter two medical fluid is converged by E, D pipeline, eventually by a kind of only medical fluid of heart.
The principle of the present invention is the pressure for being greater than top according to the pressure of lower end, so as to cause flowing up for liquid, gas
It is lighter than liquid, to take bubble out of.Medical fluid entrance 6 and medicine liquid outlet 7 be all made of it is horizontal into go out, while internal helix tube
5 and external interface inner diameter size be 3-4mm caliber, furthermore D, E, F, G use the silicone tube of 5 × φ of φ 3mm, with
Caliber for guaranteeing one 1 end portion of Rule threeway is almost the same, to be conducive to the discharge of bubble.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (5)
1. the exhaust bubble structure in a kind of Perfused isolated heart system, it is characterised in that: including installation base plate, heat insulation tank (4), two
A overflow cup and two snakelike heaters (3), installation base plate, heat insulation tank (4) and two snakelike heater (3) states in a vertical shape
Setting, two snakelike heaters (3) and heat insulation tank (4) are arranged at the same side of installation base plate, at two snakelike heaters (3)
It is arranged in sustained height, the other side of installation base plate is arranged in two overflow cups, and two overflow cups are in sustained height setting, protect
Warm tank (4) setting is in the underface in two snakelike heater (3) middle positions, each snakelike heater (3) and Rule below
The first port of threeway one (1) is connected to, the second port of two Rule threeways one (1) two with Rule threeway two (10) respectively
Port connection, the third port of Rule threeway two (10) is connect with the top of heat insulation tank (4), corresponding with Rule threeway one (1)
Also set up on installation base plate there are two T-type threeway (2), two T-type threeways (2) respectively with corresponding Rule threeway one (1) the
The connection of three ports, the upper end of each T-type threeway (2) are connected with corresponding overflow cup, and the lower end of each T-type threeway (2) connects
It is connected to a spray pump.
2. the exhaust bubble structure in a kind of Perfused isolated heart system according to claim 1, it is characterised in that: heat insulation tank
(4) helix tube (5) are equipped in, the outside upper and lower side of heat insulation tank (4) is in be horizontally disposed with to have medical fluid entrance (6) and medicine liquid outlet respectively
(7), medicine company entrance and medicine liquid outlet (7) are connect with the upper and lower side of helix tube (5) respectively, and medicine liquid outlet is connected with below (7)
Syringe needle.
3. the exhaust bubble structure in a kind of Perfused isolated heart system according to claim 2, it is characterised in that: heat insulation tank
(4) outside upper and lower side is respectively arranged with the heat preservation outlet (9) and heat preservation entrance (8) of internal connection.
4. the exhaust bubble structure in a kind of Perfused isolated heart system according to claim 3, it is characterised in that: snakelike to add
Between hot device (3) and Rule threeway one (1), between heat insulation tank (4) and Rule threeway two (10), Rule threeway one (1) and Rule
Between threeway two (10), between overflow cup and T-type threeway (2), between Rule threeway one (1) and T-type threeway (2), heat insulation tank (4)
Pass through piping connection between syringe needle.
5. the exhaust bubble structure in a kind of Perfused isolated heart system according to claim 4, it is characterised in that: pipeline with
The diameter of helix tube (5) is identical and is 3 ~ 4mm.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201910012888.3A CN109526944A (en) | 2019-01-07 | 2019-01-07 | A kind of exhaust bubble structure in Perfused isolated heart system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910012888.3A CN109526944A (en) | 2019-01-07 | 2019-01-07 | A kind of exhaust bubble structure in Perfused isolated heart system |
Publications (1)
Publication Number | Publication Date |
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CN109526944A true CN109526944A (en) | 2019-03-29 |
Family
ID=65834449
Family Applications (1)
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CN201910012888.3A Pending CN109526944A (en) | 2019-01-07 | 2019-01-07 | A kind of exhaust bubble structure in Perfused isolated heart system |
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JP2008029606A (en) * | 2006-07-28 | 2008-02-14 | Jms Co Ltd | Medical tube joint and line for use in infusion or blood transfer using the same |
JP2008220417A (en) * | 2007-03-08 | 2008-09-25 | Jms Co Ltd | Extracorporeal circulation apparatus |
US7591812B1 (en) * | 2004-01-22 | 2009-09-22 | Yehuda Tamari | Passive venous air purging chamber with vent/sucker blood handling capabilities |
CN202421174U (en) * | 2012-01-30 | 2012-09-05 | 徐州医学院 | Isolated heart perfusion device |
CN203414459U (en) * | 2013-08-27 | 2014-01-29 | 四川省医学科学院(四川省人民医院) | Isolated heart perfusion device |
JP2014016299A (en) * | 2012-07-11 | 2014-01-30 | Shimadzu Corp | Automatic analyzer and method for incorporating bubbles |
CN204699123U (en) * | 2015-04-30 | 2015-10-14 | 珠海健帆生物科技股份有限公司 | Extracorporeal circulation pipeline |
CN204763020U (en) * | 2015-02-16 | 2015-11-18 | 杭州电子科技大学 | External intelligent support system of subnormal temperature transplant organ |
CN205235040U (en) * | 2015-12-09 | 2016-05-18 | 兰州大学第一医院 | Hemoperfusion pipeline based on bright blood clearing machine of shellfish |
CN107467011A (en) * | 2017-08-14 | 2017-12-15 | 武汉大学 | A kind of liver oxygen carrying machine perfusion device |
CN207040657U (en) * | 2017-07-28 | 2018-02-27 | 武汉大学 | A kind of in vitro low temperature oxygen carrying machine perfusion device of toy liver |
-
2019
- 2019-01-07 CN CN201910012888.3A patent/CN109526944A/en active Pending
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7591812B1 (en) * | 2004-01-22 | 2009-09-22 | Yehuda Tamari | Passive venous air purging chamber with vent/sucker blood handling capabilities |
JP2008029606A (en) * | 2006-07-28 | 2008-02-14 | Jms Co Ltd | Medical tube joint and line for use in infusion or blood transfer using the same |
JP2008220417A (en) * | 2007-03-08 | 2008-09-25 | Jms Co Ltd | Extracorporeal circulation apparatus |
CN202421174U (en) * | 2012-01-30 | 2012-09-05 | 徐州医学院 | Isolated heart perfusion device |
JP2014016299A (en) * | 2012-07-11 | 2014-01-30 | Shimadzu Corp | Automatic analyzer and method for incorporating bubbles |
CN203414459U (en) * | 2013-08-27 | 2014-01-29 | 四川省医学科学院(四川省人民医院) | Isolated heart perfusion device |
CN204763020U (en) * | 2015-02-16 | 2015-11-18 | 杭州电子科技大学 | External intelligent support system of subnormal temperature transplant organ |
CN204699123U (en) * | 2015-04-30 | 2015-10-14 | 珠海健帆生物科技股份有限公司 | Extracorporeal circulation pipeline |
CN205235040U (en) * | 2015-12-09 | 2016-05-18 | 兰州大学第一医院 | Hemoperfusion pipeline based on bright blood clearing machine of shellfish |
CN207040657U (en) * | 2017-07-28 | 2018-02-27 | 武汉大学 | A kind of in vitro low temperature oxygen carrying machine perfusion device of toy liver |
CN107467011A (en) * | 2017-08-14 | 2017-12-15 | 武汉大学 | A kind of liver oxygen carrying machine perfusion device |
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