CN109512867A - The Chinese medicine composition for treating abdominal pain - Google Patents
The Chinese medicine composition for treating abdominal pain Download PDFInfo
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- CN109512867A CN109512867A CN201811455024.0A CN201811455024A CN109512867A CN 109512867 A CN109512867 A CN 109512867A CN 201811455024 A CN201811455024 A CN 201811455024A CN 109512867 A CN109512867 A CN 109512867A
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- abdominal pain
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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Abstract
The invention discloses a kind of Chinese medicine composition for treating abdominal pain, raw material includes: that white pepper, alumen, corydalis tuber, Fructus meliae toosendan, the root of three-nerved spicebush and Bi are dialled.Chinese medicine composition of the invention is herb medicinal paste for external application, not by oral administration, a variety of abdominal pain in children can be treated by being directly applied with, including the abdomen syncope due to pathogenic cold card of abdominal pain, and functional abdominal pain, functional dyspepsia FD and mesenteric lymphadenitis, diarrhea, nocturnal fretfulness in infants, dysmenorrhea etc. demonstrate,prove shower with abdomen syncope due to pathogenic cold.Abdominal pain patch preparation of the invention is simple, easy to use.
Description
Technical field
The present invention relates to traditional Chinese medicine research technical fields, and in particular to a kind of Chinese medicine composition for treating abdominal pain.
Background technique
Abdominal pain in children is pediatric common disease disease, is often referred to abdomen hereinafter, around navel and pubis is ached with upper bit
A kind of illness that pain is characterized.The reason of causing abdominal pain is more, such as roundworm disease, acute appendicitis, incarceration hernia, children's intestines convulsion
Contraction, anaphylactoid purpura, chronic gastritis, mesenteric lymphadenitis, abdomen type nettle rash etc..Except these entities that can clarify a diagnosis out
The abdominal pain of the cause of disease, abdominal pain can also be caused by experiencing cold-evil, infantile dyspeptic gastroenteropathy, qi depression to blood stasis, emotional stimulation etc..In addition, going back some abdominal pain
It can not find the specific cause of disease, substantive lesion is can not check in inspection.
Since children's body is still in the stage of development, and medication submissiveness is poor, therefore the unsuitable children of oral drugs
The treatment of abdominal pain.The external application Chinese medicine of common treatment abdominal pain is mainly patch, such as:
" abdominal pain patch treatment abdominal pain in children 350 " (Zhang Minsu, new Chinese medicine in August, 2002 the 8th phase 19-1993 of volume 34)
A kind of abdominal pain patch medicine is disclosed, object composition has wrinkled giant hyssop, the root of Dahurain angelica, perilla leaf, rhizoma corydalis, Cortex Magnoliae Officinalis, radix aucklandiae, fennel seeds etc..It treats small
A kind of functional abdominal pain 350 without alimentary infection and without Surgical Acute Venter Diseases indication of youngster, total effective rate 96%.
" 90 observation of curative effect of abdominal pain cream Acupoint Application in Treating children abdominal pain due to cold " (iron etc., Acupuncture Clinical magazine 1995
Year volume 11 the 11st, 12 phases: 21) disclosing one kind fennel seeds, evodia rutaecarpa, rhizoma zingiberis, rhizoma corydalis and break into paste made of fine powder,
Ointment is placed in omphalos, and after 90 treatments, recovery from illness accounts for 80%, and improvement accounts for 14.4%, accounts for 5.6% in vain.
" Chinese medicine application method treats infantile indigestion with food retention abdominal pain 58 " (Jiang Xia, Chinese community doctor, the 22nd phase in 2006 are (comprehensive
Close version): 68) a kind of Chinese prescription is disclosed, medicine group becomes: dried immature fruit of citron orange 15g, dried orange peel 10g, Fructus meliae toosendan 15g, Radix Paeoniae Alba 20g, rheum officinale
3g, hawthorn 10g, tuber of pinellia 5g.Mixed grinding takes 1.5g every time and fills out navel, use immobilization with adhesive tape at powder.Treating total effective rate is
91.4%.
The Chinese patent of CN105169329A discloses a kind of peaceful navel patch of abdominal pain in children, and it includes Radix Codonopsis that drug, which forms, white
Art, Poria cocos, dried orange peel, Cortex Magnoliae Officinalis, the dried immature fruit of citron orange, Radix Paeoniae Alba, Radix Angelicae Sinensis, Rhizoma Chuanxiong, corydalis tuber, cortex cinnamomi, pepper, cloves, rhizoma zingiberis and moxibustion hay.For controlling
It treats phlegm wet and becomes silted up and hinder, abdominal pain in children caused by mechanism of qi is obstructed.
The Chinese patent of CN102233010A discloses a kind of abdominal pain in children note, by the bulk pharmaceutical chemicals wrinkled giant hyssop, root of Dahurain angelica, purple perilla, white
Chinese herbaceous peony, Radix Glycyrrhizae, corydalis tuber, radix aucklandiae, fennel seeds and auxiliary material glycerol, sodium cellulose glycolate, sorbierite composition, for treating children's paroxysm
Property abdominal pain.
Although the Chinese herbs paste for the treatment of abdominal pain in children there are some reports, it generally can only be directed to some type of abdomen
Pain is treated effectively, and most of patch medicine components are more, and complicated component, children bear a pretty, delicate skin, and each internal organs of system are immature,
The uncertainty of drug side-effect is improved using multi-component Chinese medicine compound prescription, drug risk increases.
Summary of the invention
The object of the present invention is to provide one kind to the medicative Chinese medicine composition of a plurality of types of abdominal pain, the Chinese medicine
Composition components are simple, and drug effect is significant.
The first aspect of the present invention, provides a kind of Chinese medicine composition for treating abdominal pain, raw material include: white pepper, alumen,
Corydalis tuber, Fructus meliae toosendan, the root of three-nerved spicebush and Bi are dialled.
The nearly mature or ripening fruits of the drying that white pepper is Piperaceae plant PipernigrumL..Autumn end is to secondary spring fruit
Harvesting when reddening wipes pulp with the water retting a few days, dries, and is white pepper.White pepper surface canescence or yellowish white are put down
It is sliding, there is the linear striped of most light color between top and base portion.The main chemical compositions of white pepper include alisol, piperine, pepper
Aldehyde, N- isobutyl group-(2E, 4E, 12Z)-octadecyl -1- amide, syringic acid, 5 hydroxymethyl furfural etc..
Alumen is alum KAl (SO4)2·12H2O is through anhydrous K Al (SO made of fumed4)2.Net alum is taken, is forged according to method of direct calcination
It is extremely crisp.
Corydalis tuber also known as rhizoma corydalis are the dried pieces of papaveraceae plant corydalis CorydalisyanhusuoW.T.Wang
Stem.Early summer cauline leaf is excavated when withered, removes fibrous root, is cleaned, and is set when boiled in boiling water to proper without the white heart, is taken out, dry.Section is yellow
Color, cutin sample have waxy gloss.The main chemical compositions of corydalis tuber include Corydaline, tetrahydropalmatine,
Pontevedrine, Tetrahydrocoptisine, dehydrocorydaline, former Protopine etc..
Fructus meliae toosendan is the dry mature fruit of Meliaceae plant melia toosendan MeliatoosendanSieb.etZucc.Winter fruit
It is harvested when mature, removes impurity, it is dry.
The root of three-nerved spicebush is the dried root of lauraceae plant root of three-nerved spicebush Lindera aggregata (Sims) Kosterm..It is annual
Excavation removes radicula, cleans, takes advantage of fresh slices, dry, or directly dry.
The nearly mature or mature fruit cluster of drying that Bi dials as Piperaceae plant fructus piperis longi Piper longum L..Fruit ear is by green change
It is harvested when black, removes impurity, dry.
Above-mentioned raw materials medicine can be used in formula, the water and/or organic solvent that above-mentioned raw materials medicine also can be used take object.
In inventive formulation, white pepper is monarch drug in a prescription, pungent, warm, enters stomach, large intestine channel.Warming spleen and stomach for dispelling cold, lower gas dissolving phlegm.The root of three-nerved spicebush and
It is ministerial drug that Bi, which is dialled, and the root of three-nerved spicebush is pungent, warm, enters spleen, lung, kidney, bladder meridian.Promoting qi circulation and relieving pain, warming kidney for dispelling cold.The Bi property dialled is pungent, heat.Return stomach, spleen,
Large intestine channel.Warming spleen and stomach for dispelling cold, lower gas analgesic.Corydalis tuber and Fructus meliae toosendan are adjutant.Corydalis tuber acrid, bitter, warm.Return liver, spleen, the heart channel of Hang-Shaoyin.Huoxue San "
The stasis of blood, sharp gas analgesic.Fructus meliae toosendan is bitter, trembles with fear.Return liver, small intestine, bladder meridian.It is soothing the liver to expel the heat-evil, promoting qi circulation and relieving pain.Alumen is to make medicine.
It is optional or preferred, above-mentioned Chinese medicine composition, by weight score meter, each raw material dosage are as follows: 2~3 parts of white pepper, withered
2~3 parts of alum, 4~6 parts of corydalis tuber, 4~6 parts of Fructus meliae toosendan, 4~6 parts of the root of three-nerved spicebush and Bi dial 3~5 parts.
The second aspect of the present invention provides a kind of abdominal pain patch, and effective component includes the Chinese medicine group of any description above
Close object.
Optional or preferred, above-mentioned abdominal pain patch further includes auxiliary material, the auxiliary material be selected from glycerol, vaseline, Laurocapram,
One of paraffin, lanolin, honey are a variety of.
Optional or preferred, above-mentioned abdominal pain patch further includes dressing patch, the dressing patch by spun laced fabric, stretch fabric, non-woven fabrics,
One or more of adhesion-proof cloth, release paper, pressure sensitive adhesive, PU film adhesive plaster composition.Wherein preferred PU film adhesive plaster, waterproofness, thoroughly
It is moist good；Slim softness, portable propelling, not pickup stain, clean hygiene is Clear & Transparent, slightly high.Chinese medicine composition powder is led to
It crosses auxiliary material and is mixed and made into cake and be fixed on dressing patch again, can be placed directly against on skin and be treated, it is very convenient.
It is optional or preferred, above-mentioned abdominal pain patch the preparation method comprises the following steps: that each raw material is ground into fine powder is spare, take vaseline to put
Enter vessel in heating to boil, Guan Huo；Fine powder is uniformly poured into container, edge to edge stirring, subject at pureed, placing cooling is in
Paste.
Abdominal pain of the invention is attached in use, should be noted following item:
1, every time application 3 hours, if occur rubefaction or consciously itch be difficult to endure, please throw off, not grab in advance
It scratches；If there is skin ulceration, timely Office visits are needed；
If 2, children age is smaller, application time should suitably shorten；
3, it is not suitable for the case where sticking: according to dialectical category heat symptom-complex person；To sticking drug extreme sensitivity, special constitution and contact
The dermatosis patients such as property dermatitis；Stick the acupuncture point local skin person that has ulceration.
4, careful user:
High fever, angina pectoris, local skin fester, pregnant woman, 3 months or less children, cloth hypersensitivity person is used with caution；
It is magnetic ingredient since some stick drug, the cardiac to implant a pacemaker will be used with caution.
Compared with prior art, the invention has the following advantages:
Chinese medicine composition of the invention, not by oral administration, a variety of abdominal pain in children, including the abdomen of abdominal pain can be treated by being directly applied with
Portion's syncope due to pathogenic cold card and functional abdominal pain, functional dyspepsia FD and mesenteric lymphadenitis, the companions such as diarrhea, nocturnal fretfulness in infants, dysmenorrhea
There is abdomen syncope due to pathogenic cold to demonstrate,prove shower.
Abdominal pain patch preparation of the invention is simple, easy to use.
Specific embodiment
Formula, preparation method, the using effect etc. of the present invention will be described in detail combined with specific embodiments below Chinese medicine composition.
The patch preparation of 1 abdominal pain of embodiment
Formula: 2~3g of white pepper, 2~3g of alumen, 4~6g of corydalis tuber, 4~6g of Fructus meliae toosendan, the root of three-nerved spicebush 4~6g and Bi dial 3~
5g。
The raw materials used drug weight part composition of each embodiment of table 1
| Number | White pepper | Alumen | Corydalis tuber | Fructus meliae toosendan | The root of three-nerved spicebush | Bi is dialled |
| Prescription 1 | 2g | 2g | 4g | 4g | 4g | 3g |
| Prescription 2 | 3g | 3g | 6g | 6g | 6g | 5g |
| Prescription 3 | 3g | 2g | 4g | 4g | 4g | 3g |
| Prescription 4 | 2g | 3g | 5g | 5g | 5g | 4g |
| Prescription 5 | 2g | 2g | 5g | 6g | 5g | 5g |
| Prescription 6 | 2g | 3g | 6g | 4g | 6g | 6g |
| Prescription 7 | 3g | 3g | 4g | 5g | 6g | 4g |
| Prescription 8 | 2g | 2g | 4g | 5g | 5g | 6g |
Preparation: it is spare to be ground into fine powder for drug, takes vaseline to be put into vessel in heating and boils, Guan Huo.Fine powder is uniform
It pours into container, edge to edge stirring, subject at pureed, placing cooling is in paste, and round pie is made in ointment.
Application method: by round pie external application of ointment in the abdomen middle part of gastric cavity, SHENQUE acupoint, anti-anaphylaxis immobilization with adhesive tape applies 3h, daily every time
1 time, 1 week as a treatment course.
2 abdominal pain of embodiment is pasted for treating functional abdominal pain
Certain Pediatric Clinic case, 4~13 years old case age.Meet functional abdominal pain after diagnosing, using random digits table,
Infant is randomly divided into two groups, treatment group and control group each 37.
Diagnostic criteria:
Referring to IV standard of Rome of Functional Gastrointestinal Disease, before diagnosis, at least 2 months symptoms meet following all conditions,
And 4 abdominal pain at least occur for every month:
(1) ictal or persistent abdominal pain is not exclusively related to physiological event (such as feed, menstrual period)；
(2) diagnostic criteria of IBS, FD or abdominal migraine is not met；
(3) by appropriate assessment, abdominal pain cannot be explained with other diseases.
Meet the case of above-mentioned standard, while meeting abdomen syncope due to pathogenic cold card diagnostic criteria (abdominal pain is more acute, and sore spot happiness is warm, obtains warm
Then relax, pain exaggerated by catching cold, pale tongue, white,slippery and moist fur).
Exclusion criteria:
(1) intraperitoneal organic disease patient, such as it is alimentary infection (acute appendicitis, colitis), Gastrointestinal Obstruction, slow
Property entembole etc.；
(2) other function gastrointestinal disease (FAPD) patient, such as irritable bowel syndrome (IBS), functional dyspepsia FD (FD)
Or abdominal migraine etc.；
(3) with the infant of obvious Behavioral disturbances；
(4) there are alarm features, i.e. fever, bleeding, anaemia, the weight decline of non-deliberately property or physical examination is found
The abdominal mass that can not be explained with Functional Gastrointestinal Disease；
(5) merge the primary patients such as severe cardiac, liver, kidney, digestion and hemopoietic system.
(6) drug for having alleviation to colic symptoms or other treatment means person were used in this patch first 24 hours；
(7) allergic constitution (to the above allergies person of 2 classes), or to trial drug composition (including matrix component)
Allergy sufferers；
(8) according to the judgment of doctors, it be easy to cause person lost to follow-up.
Fall off rejecting standard:
(1) there are allergic reaction or serious adverse events, experimenter should be stopped according to the judgment of doctors；
(2) during testing, patient's secondary infection, or other diseases, the person of affecting the treatment occurs；
(3) subject's compliance is poor, or automatic midway dressing；
(4) the midway unblinding case of a variety of causes；
(5) no matter which kind of reason, patient is unwilling or can not continue clinical test, exits to physician proposition
Test requirements document and stop experimenter；
(6) though subject is not known proposes to exit test, no longer receive medication and detection and person lost to follow-up.
Treatment group: the abdominal pain patch of prescription 2 in embodiment 1 is given, round pie is made in medicine end, is externally applied to umbilical region, anti-anaphylaxis glue
Cloth is fixed, and applies 3h every time, one time a day.
Control group: giving the patch treatment for the treatment of group's half dose, be externally applied to umbilical region, and 3h is applied in anti-anaphylaxis immobilization with adhesive tape every time,
One time a day.
Two groups of courses for the treatment of are 4 weeks, and treatment sets up intermediate interview point in 2 weeks.It exhorts that infant and parent want reasonable diet, avoided
Hungry, satiety, the product for the stimulation such as avoid pungent food, is cold and cool, and give psychological counseling.
Abdominal pain degree standards of grading:
1 point: without colic symptoms；
2 points: abdominal pain lesser extent is only told abdominal pain, the movement of unused hand Continued depression abdomen, and can be continued just
In the activity of progress；
3 points: abdominal pain is heavier, the movement of useful hand Continued depression abdomen, but still to continue ongoing activity,
And the person of going to see a doctor when selecting；
4 points: abdominal pain degree weight, the movement of useful hand Continued depression abdomen, and ongoing activity can not be continued, it needs
Immediately do not go to see a doctor person.
Abdominal pain breaking-out duration standards of grading:
1 point: no abdominal pain breaking-out remembers 1 point；
2 points: abdominal pain be it is slight, the abdominal pain duration < 15min, abdomen is slightly swollen, remember 2 points；
3 points: abdomen is moderate, and abdominal pain continues 15-30min, and abdomen is more swollen, remembers 3 points；
4 points: abdominal pain is severe, and the abdominal pain duration > 30min, abdominal distension is obvious, remembers 4 points.
Abdominal pain seizure frequency standards of grading:
1 point: no abdominal pain breaking-out remembers 1 point；
2 points: abdominal pain be it is slight, abdominal pain number is monthly < 4 time；
3 points: abdominal pain is moderate, abdominal pain number monthly >=4 time, and < 12 times；
4 points: abdominal pain is severe, and abdominal pain number is monthly >=12 time.
The evaluation of disease total effects
Recovery from illness: colic symptoms disappear, without recurrence in March；
Effective: abdominal pain degree, attack times and duration integral reduce 2 points altogether；
Effective: abdominal pain degree, attack times and duration integral reduce 1 point altogether；
Invalid: abdominal pain is integrated without improvement without reduction.
It is for statistical analysis to all data using 24.0 software of SPSS.
Paired t-test is relatively used in measurement data group；Comparison among groups use independent samples t test；Ranked data use
Rank sum test.P < 0.05 is that difference is statistically significant.
During test, treatment group falls off rejecting 2, and 1 lost to follow-up, 1 plus is treated with other drugs, actually accomplishes 35
Example；Control group falls off rejecting 2, and 2 are treated plus with other drugs, actually accomplish 35.
Treatment group: male 19, female 16；Age 4-12 years old；The course of disease 3-34 month.
Control group: male 17, female 18；Age 4-12.5 years old；The course of disease 4-35 month.
Treatment results:
2 two groups of Clinical efficacy comparisons of table
| Group | Number of cases | Recovery from illness | It is effective | Effectively | In vain | It is total effective |
| Control group | 35 | 1 (2.86%) | 10 (28.57%) | 16 (45.71%) | 8 (22.86%) | 27 (77.14%) |
| Treatment group | 35 | 5 (14.29%) | 17 (48.57%) | 11 (31.43%) | 2 (5.71%) | 33 (94.29%) |
Treatment group's total effective rate is 94.29%, cure-remarkable-effectiveness rate 62.86%, hence it is evident that is better than control group, two comparison among groups, difference
Statistically significant (P < 0.05).Show that treatment group is substantially better than control group, abdominal pain pastes high dose group clinical efficacy and is better than low dose
Amount group.
3 two groups of table pretherapy and post-treatment abdominal pain degree compare
| Group | Case load | Before treatment | After treatment | t | p |
| Control group | 35 | 3.63±0.490 | 2.83±0.747 | 5.938 | < 0.05 |
| Treatment group | 35 | 3.57±0.502 | 2.26±0.741 | 8.639 | < 0.05 |
| t | 0.482 | 3.212 | |||
| p | > 0.05 | < 0.05 |
Two groups of infant abdominal pain degree scorings significantly reduce (P < 0.05) before relatively treating after treatment；Treatment group's infant after treatment
The scoring of abdominal pain degree is substantially less than control group (P < 0.05).
4 two groups of table pretherapy and post-treatment abdominal pain seizure frequency scorings are compared
The scoring of infant abdominal pain seizure frequency significantly reduces (P < 0.05) before relatively treating；Treatment group's infant abdominal pain is sent out after treatment
Working frequency scoring is substantially less than control group (P < 0.05).
5 two groups of table pretherapy and post-treatment abdominal pain breaking-out duration scorings are compared
| Group | Case load | Before treatment | After treatment | t | p |
| Control group | 35 | 3.60±0.497 | 2.54±0.657 | 8.178 | < 0.05 |
| Treatment group | 35 | 3.63±0.490 | 2.20±0.759 | 11.435 | < 0.05 |
| t | 0.242 | 3.212 | |||
| p | > 0.05 | < 0.05 |
Two groups of infant abdominal pain breaking-out duration scorings significantly reduce (P < 0.05) before relatively treating after treatment；It is controlled after treatment
Treatment group infant abdominal pain breaks out duration scoring substantially less than control group (P < 0.05).
Conclusion:
It is 94.29% that abdominal pain, which pastes high-dose therapy children functional abdominal pain curative effect total effective rate, cure-remarkable-effectiveness rate 62.86%, compared with
Low dosage is imitated.
It can obviously reduce abdominal pain seizure frequency, mitigate abdominal pain degree, shorten abdominal pain and break out the duration.
Adverse reaction is not found, it is safe and reliable.
3 abdominal pain of embodiment patch is used for other types abdominal pain
Clinical application example:
Between 2014~2018 years, following clinic case is directed on certain hospital clinical, using the traditional chinese medicine composition of the invention patch,
Specific case is to should look like this:
First group: abdominal pain abdomen syncope due to pathogenic cold card
Case-data: patient age half years old to 12 years old, amounting to 58, wherein male 22, female 36.
Clinical manifestation is abdomen arrested anxious pain, and sore spot happiness is warm, get Wen Zeshu, pain exaggerated by catching cold, and agitation is cry and screamed, pale complexion,
Limb cold it is not warm or and vomit and diarrhoea, clear abundant urine, pale tongue, white,slippery and moist fur.
Second group: functional dyspepsia FD
Medical history information: the age 7 months to 11 years old, amounting to 64, wherein male 35, female 29.
Diagnostic criteria:
(1) malaise symptoms such as epigastric pain, abdominal distension, early satiety, belch, loss of appetite, nausea, anorexia, sour regurgitation, vomiting, through examining
Look into the organic disease for excluding to cause above-mentioned symptom.
(2) continue or Recurrent Abdominal Pain 2 months or more, at least 1 time weekly, without alleviation after defecation.
(3) inflammation, organic, metabolic disease or tumour are excluded.
Partial symptoms are demonstrate,proved with abdomen syncope due to pathogenic cold simultaneously.
Third group: mesenteric lymphadenitis
Case-data: patient age half years old to 12 years old, 53 are amounted to, male 28, female 25.
Clinical manifestation is fever, abdominal pain, vomiting etc., sometimes with diarrhea or constipation, wherein 18 swollen with cervical lymph node
Greatly.Exclude that acute appendicitis, enterocinesia be hyperfunction, intestines ascariasis after diagnosing.Partial symptoms are demonstrate,proved with abdomen syncope due to pathogenic cold simultaneously.
4th group: diarrhea
Case-data: patient age 5 months to 4 years old, wherein accounting for 2/3rds within 2 years old, 45 are amounted to, 20 male, female
25.
Clinical manifestation is uneasy, loss of appetite of crying, and occasionally has vomiting or the cream that overflows.It is warmed up with abdominal pain and sore spot happiness, obtains Wen Ze
Relax, pain exaggerated by catching cold, agitation is cry and screamed, pale complexion, limb cold it is not warm or and vomit and diarrhoea, clear abundant urine, pale tongue, at least one in white,slippery and moist fur
?.Daily times of defecation is more than 2 times, the dilute water sample of serious person stool.Stool microscopy shows fat globule, rare pyocyte, red thin
Born of the same parents.
5th group: nocturnal fretfulness in infants
Case-data: patient age 10 days to 1 years old, 23 are amounted to, male 14, female 19.
Clinical manifestation is that steady and sure can not fall asleep at night, and intermittent to cry loudly, irritated more than, daytime is as usual.While with
Abdomen syncope due to pathogenic cold demonstrate,proves partial symptoms.
Treatment method: the abdominal pain patch of Examples 1 to 8 composition of raw materials preparation makes according to conditions of patients degree and age selection
With one formula, it is externally applied to the abdomen middle part of gastric cavity, SHENQUE acupoint, 3h is applied in anti-anaphylaxis immobilization with adhesive tape every time, and one time a day, 1 week as a treatment course.Most
It is 2 days short, three course for the treatment of of longest.It is still invalid after one course for the treatment of that abdominal pain of the present invention is stopped using to paste, nothing after baby diarrhea group uses 1 day
What is alleviated stops using abdominal pain of the present invention to paste, and reformulates other treatment schemes.The label stopped using is.
Curative effect determinate standard:
It is effective: the colic symptoms disappear or mostly disappear after medication
Improving: there is substantially reduced colic symptoms before relatively treating after medication；
Invalid: symptom is unchanged before relatively treating after medication or aggravates.
Total effective rate=obvious effective rate+improvement rate.
6 clinical efficacy result of table
| Group | Case load | Effectively | It improves | In vain | Total effective rate |
| First group | 58 | 29 | 26 | 3 | 94.83% |
| Second group | 46 | 26 | 18 | 2 | 95.65% |
| Third group | 64 | 38 | 24 | 2 | 96.88% |
| 4th group | 53 | 30 | 19 | 4 | 92.45% |
| 5th group | 45 | 24 | 18 | 3 | 93.33% |
Dysmenorrhea clinical case:
Lee, female 18 years old, continue abdominal pain, happiness pressing, aversion to cold and preference for warmth is dark through water colour, and amount is normal, and four limbs are not during passing through
Temperature, small eilema, pale complexion, the weary inability of body.It is pasted using the abdominal pain of prescription 1, is externally applied to abdomen SHENQUE acupoint, anti-anaphylaxis adhesive plaster is solid
It is fixed, 3h is applied every time, and one time a day, symptom is substantially reduced after pasting using abdominal pain, continues to use after menstrual period, continues to 1 week.Afterwards
Phase, Effect of follow-up visit by telephone indicated no recurrence without further consultation.
Mr. Wang, female 21 years old, have a pain, menstrual period blood volume is few, pale complexion, and body is weary for 2-3 days before menstrual period to underbelly silk floss during passing through
It is powerless, occasionally there is dizziness.It pasting using the abdominal pain of prescription 3, is externally applied to abdomen SHENQUE acupoint, 3h is applied in anti-anaphylaxis immobilization with adhesive tape every time, and daily 1
Secondary, pain symptom mitigates after being pasted using abdominal pain, and complexion is restored, and dizziness disappears.It continues to use, continues to 1 week after menstrual period.Afterwards
Phase, Effect of follow-up visit by telephone indicated no recurrence without further consultation.
Zhang, female, 36 years old, menstrual period underbelly intermittent paroxysm severe pain, Mao Lenghan continued or so half an hour alleviation, four limbs
Send out cool, it is dark through color, carry clot, once in a while nausea and vomiting secretly.It is pasted using the abdominal pain of prescription 6, is externally applied to abdomen SHENQUE acupoint, anti-anaphylaxis glue
Cloth is fixed, and applies 3h every time, one time a day.Pain symptom is substantially reduced after being pasted using abdominal pain.It continues to use, amounts to after menstrual period
Three courses for the treatment of, recovery from illness.
Specific case used herein elaborates inventive concept, the explanation of above example is only intended to
Help understands core of the invention thought.It should be pointed out that for those skilled in the art, not departing from this
Under the premise of inventive concept, any obvious modification, equivalent replacement or the other improvements made should be included in the present invention
Protection scope within.
Claims (5)
1. a kind of Chinese medicine composition for treating abdominal pain, which is characterized in that raw material includes: white pepper, alumen, corydalis tuber, Fructus meliae toosendan, crow
Medicine and Bi are dialled.
2. Chinese medicine composition according to claim 1, which is characterized in that score meter by weight, each raw material dosage are as follows: white Hu
2~3 parts of green pepper, 2~3 parts of alumen, 4~6 parts of corydalis tuber, 4~6 parts of Fructus meliae toosendan, 4~6 parts of the root of three-nerved spicebush and Bi dial 3~5 parts.
3. a kind of abdominal pain patch, which is characterized in that effective component includes Chinese medicine composition of any of claims 1 or 2.
4. abdominal pain patch according to claim 3, which is characterized in that further include auxiliary material, the auxiliary material is selected from glycerol, all scholars
One of woods, Laurocapram, paraffin, lanolin, honey are a variety of.
5. abdominal pain patch according to claim 3 or 4, which is characterized in that the preparation method comprises the following steps: it is standby that each raw material is ground into fine powder
With, it takes vaseline to be put into vessel in heating and boils, Guan Huo；Fine powder is uniformly poured into container, edge to edge stirring, to be at pureed
Standard, placing cooling is in paste.
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| CN111920891A (en) * | 2020-09-27 | 2020-11-13 | 四川省中医药科学院中医研究所 | Medicine composition for warming middle energizer and relieving pain and preparation method and application thereof |
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| CN108635443A (en) * | 2018-07-28 | 2018-10-12 | 遵义医学院珠海校区 | A kind of navel paster for treating abdominal distention |
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| CN108635443A (en) * | 2018-07-28 | 2018-10-12 | 遵义医学院珠海校区 | A kind of navel paster for treating abdominal distention |
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| CN111920891A (en) * | 2020-09-27 | 2020-11-13 | 四川省中医药科学院中医研究所 | Medicine composition for warming middle energizer and relieving pain and preparation method and application thereof |
| CN111920891B (en) * | 2020-09-27 | 2022-02-22 | 四川省中医药科学院中医研究所 | Medicine composition for warming middle energizer and relieving pain and preparation method and application thereof |
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Application publication date: 20190326 |