CN109498778B - Antiviral oral liquid with good taste and production process thereof - Google Patents

Antiviral oral liquid with good taste and production process thereof Download PDF

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Publication number
CN109498778B
CN109498778B CN201811385879.0A CN201811385879A CN109498778B CN 109498778 B CN109498778 B CN 109498778B CN 201811385879 A CN201811385879 A CN 201811385879A CN 109498778 B CN109498778 B CN 109498778B
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oral liquid
box body
body shell
plate
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CN109498778A (en
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卢强
傅兆瑞
苏悌
章璇
赵志杰
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Anhui Dongsheng Youbang Pharmaceutical Co ltd
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Anhui Dongsheng Youbang Pharmaceutical Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26Accessories or devices or components used for biocidal treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/02Cleaning by the force of jets or sprays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04Cleaning involving contact with liquid
    • B08B3/10Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
    • B08B3/14Removing waste, e.g. labels, from cleaning liquid; Regenerating cleaning liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/21Pharmaceuticals, e.g. medicaments, artificial body parts

Abstract

The invention discloses an antiviral oral liquid with good taste and a production process thereof, wherein each 1100ml of the oral liquid is prepared from the following raw materials: 45.5g of isatis root, 8.5g of weeping forsythia, 12.5g of cablin potchouli herb, 15g of grassleaf sweelflag rhizome, 27g of gypsum, 18g of turmeric root-tuber, 35g of common anemarrhena rhizome, 13g of reed rhizome, 18g of rehmannia root, 12g of cane sugar, 9g of honey and 11g of xylitol, and the antiviral oral liquid with good taste is prepared by the following steps of: the method comprises the following steps: putting the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root into an extraction tank, adding water, and decocting the decoction pieces twice by using boiling water, wherein the time for decocting the decoction pieces for the first time is 3.2 hours; the antiviral oral liquid with good taste and the production process thereof can effectively improve the drinking taste of the antiviral oral liquid, improve the working efficiency of sterilization operation in the production link, play a role in fixing and protecting the finished oral liquid product in the sterilization process, enable the sterilization operation link to have a water body circulation structure, reduce resource waste and be more practical.

Description

Antiviral oral liquid with good taste and production process thereof
Technical Field
The invention belongs to the field of medicines, and particularly relates to antiviral oral liquid, and more particularly relates to antiviral oral liquid with good taste and a production process thereof.
Background
The antiviral oral liquid is a safe, effective, reasonable in price and convenient to use medicine, the traditional Chinese medicines are all traditional Chinese medicines commonly used in clinic, the treatment effect is obvious, the side effect is small, the use is convenient, a patient in need can use the antiviral oral liquid at ease, the antiviral oral liquid is an antiviral medicine, is an over-the-counter medicine for the cold of the department of medicine, is a composite preparation mainly composed of active ingredients such as radix isatidis, gypsum, rhizoma phragmitis, radix rehmanniae, radix curcumae, rhizoma anemarrhenae, rhizoma acori graminei, herba pogostemonis and fructus forsythiae, and auxiliary materials such as cane sugar, honey, sodium cyclamate, orange essence and the like, has the effects of clearing heat, eliminating dampness, cooling blood and detoxifying, contains various antiviral ingredients inside, can effectively inhibit viruses, can be quickly absorbed, quickly takes effect, and is a first-choice medicine for treating and preventing various viral infections such as cold, upper respiratory infection, parotitis, hand-foot-and mouth disease and the like;
present antiviral oral liquid has certain drawback at the in-process that uses, the taste of traditional antiviral oral liquid is relatively poor, because contain the reed rhizome in the antiviral oral liquid, radix rehmanniae, the curcuma aromatica, the concentrated liquid medicine of medicines such as rhizoma anemarrhenae, make the taste of antiviral oral liquid bitter, after the user took the antiviral oral liquid, the bitter can exist a period of time in the mouth, traditional antiviral oral liquid is disinfecting the in-process of monitoring carrying out, the user need place the medicine finished product in batches, required time when having increased disinfection detection procedure, the sterilizer is directly placed in to the medicine bottle goods shelves, make its rocking phenomenon appear in spraying the disinfection process easily, thereby cause breaking of medicine bottle, traditional disinfection detection link does not have the water cycle structure, this link can waste a large amount of water resources, bring certain adverse effect for the user.
Disclosure of Invention
In order to overcome the technical problems, the invention aims to provide an antiviral oral liquid with good taste and a production process thereof, 11g of xylitol is added into the original antiviral oral liquid, when a user drinks the antiviral oral liquid, the xylitol can improve the sweetness of the antiviral oral liquid under the condition of not increasing the sugar content in the antiviral oral liquid, and simultaneously, after the user drinks the antiviral oral liquid, the oral cavity of the user is cleaned, the bitter taste in the mouth of the user is reduced, so that the drinking taste of the antiviral oral liquid is effectively improved, through the arrangement of the movable buckle plate, when the user carries out air tightness detection and disinfection treatment on the packaged antiviral oral liquid, the user can carry a large amount of antiviral oral liquid by using a push-pull flat wagon, the movable buckle plate clamps and fixes two sides of the push-pull flat wagon by using a spring pin, so that the push-pull flat wagon and a box shell keep a relatively fixed state, thereby the object on the push-pull flat car is transferred more stably, the phenomenon that antiviral oral liquid is scattered in the process of cleaning detection is avoided, the safety of the operation link is improved, by arranging the solenoid and the fixed lining plate, when the trolley filled with the antiviral oral liquid enters the sterilization cabinet, the controller enables the surface coil of the solenoid to be electrified, the iron core inside the solenoid is magnetized, the electrified solenoid can be used for carrying out magnetic adsorption and fixation on the trolley entering the sterilization cabinet, thereby the phenomenon that the antiviral oral liquid on the trolley shakes in the process of spraying and cleaning is avoided, the stability in the cleaning process is increased, by arranging the drainage plate and the filter box, after the finished product of the antiviral oral liquid is cleaned and disinfected, the water consumed in the cleaning process enters the filter box through the drainage groove of the drainage plate, and is filtered by the four layers of filter plates of the filter box, the water can be guided into the spherical spray head through the guide pipe to carry out secondary cleaning operation, thereby reducing the water resource consumed during the production cycle and achieving a certain energy-saving effect.
The purpose of the invention can be realized by the following technical scheme:
an antiviral oral liquid with good taste is prepared from the following raw materials per 1100 ml: 45.5g of isatis root, 8.5g of weeping forsythia, 12.5g of cablin potchouli herb, 15g of grassleaf sweelflag rhizome, 27g of gypsum, 18g of turmeric root-tuber, 35g of common anemarrhena rhizome, 13g of reed rhizome, 18g of rehmannia root, 12g of cane sugar, 9g of honey and 11g of xylitol, and the antiviral oral liquid with good taste is prepared by the following steps of:
the method comprises the following steps: putting the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root into an extraction tank, adding water, boiling and decocting the decoction pieces twice by using boiling water, wherein the time for boiling for decocting for the first time is 3.2 hours, cooling for 1.5 hours, precipitating the decoction dregs, and decocting for the second time;
step two: pouring the decocted mixture into a straight barrel extraction tank, extracting volatile oil and hair oil emulsion, pouring the residual liquid into an alcohol precipitation tank, precipitating solid residues by using the alcohol precipitation tank, filtering out liquid medicine residues after liquid medicine is precipitated, concentrating the liquid medicine to 55% by using a double-effect concentrator, adding a volatile oil inclusion compound and a proper amount of honey, cane sugar, orange essence and xylitol into the liquid medicine, and removing the bitter taste in the original liquid medicine;
step three: adjusting pH with 12% sodium hydroxide solution, filtering with filter to obtain concentrated medicinal liquid, adding water to 1100ml, mixing the liquids, bottling with oral liquid bottle filling machine, and sterilizing with sterilizing cabinet to obtain the final product.
A production process of antiviral oral liquid with good taste comprises the following steps:
step one; putting the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root into an extraction tank, adding water, boiling and decocting the decoction pieces twice by using boiling water, wherein the time for boiling for decocting for the first time is 3.2 hours, cooling for 1.5 hours, precipitating the decoction dregs, and decocting for the second time;
step two: pouring the decocted mixture into a straight barrel extraction tank, extracting volatile oil and hair oil emulsion, pouring the residual liquid into an alcohol precipitation tank, precipitating solid residues by using the alcohol precipitation tank, filtering out liquid medicine residues after liquid medicine is precipitated, concentrating the liquid medicine to 55% by using a double-effect concentrator, adding a volatile oil inclusion compound and a proper amount of honey, cane sugar, orange essence and xylitol into the liquid medicine, and removing the bitter taste in the original liquid medicine;
step three: adjusting pH with 12% sodium hydroxide solution, filtering with filter to obtain concentrated medicinal liquid, adding water to 1100ml, mixing the liquids, bottling with oral liquid bottle filling machine, and sterilizing with sterilizing cabinet to obtain the final product.
A production process of antiviral oral liquid with good taste comprises the following steps that in the third step, the sterilization cabinet comprises a box body shell, a fixed lining plate, a movable buckle plate and a filter box, wherein a push-pull flat car is installed on the outer surface of the front end of the box body shell, four groups of damping pulleys are fixedly installed on the outer surface of the lower end of the box body shell, two groups of limiting sliding grooves are formed in the inner side of the upper part of the push-pull flat car, and a push-pull handle is fixedly installed on the outer surface of the upper end of the push-pull flat car;
an operation knob is movably mounted on the outer surface of the front end of the box body shell, two groups of pressure gauges are fixedly mounted on the outer surface of the front end of the box body shell, which is close to the upper portion of the operation knob, a sealing door plate is movably mounted on the front portion of the box body shell, two groups of air exhaust grooves are formed in the inner side of the sealing door plate at equal intervals, a fixing washer is fixedly mounted on the outer surface of the front end of the sealing door plate, four groups of ball nozzles are mounted at the top of the inner side of the box body shell at equal intervals, a vacuum machine is fixedly mounted on the outer surface of the upper end of the box body shell, two groups of communicating pipes are fixedly mounted on one side, which is close to the vacuum machine, of the outer surface of the upper end of the box body shell, and the push-pull flat car is fixedly connected with the box body shell through a movable pinch plate;
the elastic clamping piece is arranged on the lower portion of the movable buckling plate, the movable buckling plate and the elastic clamping piece are fixedly connected through a connecting bolt head, spring pins are fixedly arranged on two sides of the connecting bolt head, four groups of fixing bolts penetrate through the lower portion of the elastic clamping piece, the fixing lining plate is arranged on the inner side of the box body shell, the fixing ring is sleeved on the upper portion of the fixing lining plate, five groups of solenoids are arranged on the inner side of the fixing ring, an upper sealing plate is fixedly arranged at the top end of the fixing lining plate, the filter box is arranged on the inner side of the bottom of the box body shell, a drainage plate is arranged on the upper portion of the filter box, and four groups of filter plates are arranged on the inner side of the filter box at equal intervals;
the utility model discloses a filter box, including the filter tank, the one end of filter tank, the inboard equidistant two sets of drainage grooves that are equipped with of upper portion of drainage plate, the lower extreme surface fixed mounting of box shell has four groups of landing legs of moving away to avoid possible earthquakes, and the inboard movable mounting of landing leg of moving away to avoid possible earthquakes has three damping spring of group, and damping spring's upper end movable mounting has the screw thread tube head, the bottom fixed mounting of landing leg of moving away to avoid possible earthquakes has anti-skidding heelpiece, the inboard of screw thread tube head is equipped with fastening screw, one side surface through connection of box shell has two sets of inlet tubes, the controller is installed to the bottom of fixed welt.
As a further scheme of the invention, the inner surface of one side of the movable buckle plate is provided with a fixed clamping groove, and the longitudinal movement range of the movable buckle plate is zero to seven points and five centimeters.
As a further scheme of the invention, four groups of induced fans are installed on the inner side of the vacuum machine, and a dust cover is embedded on the inner side of the front end of the vacuum machine.
As a further scheme of the invention, two groups of limiting clamping seats are arranged in the box body shell, and the bottom of the box body shell is of a hollow structure.
As a further scheme of the invention, the bottom of the flow guide pipe is sleeved with two groups of filter heads, and the flow guide pipe is fixed in a threaded manner.
As a further scheme of the invention, the rotation angle range of the sealing door plate is 0-180 degrees, and four groups of lock bolts are embedded in the inner side of the sealing door plate at equal intervals.
The invention has the beneficial effects that:
1. according to the antiviral oral liquid with good mouthfeel, 11g of xylitol is added into the original antiviral oral liquid, when a user drinks the antiviral oral liquid, the xylitol can improve the sweetness of the antiviral oral liquid under the condition that the sugar content in the antiviral oral liquid is not increased, and meanwhile, after the user drinks the antiviral oral liquid, the oral liquid has a cleaning effect on the oral cavity of the user, the bitter taste in the oral cavity of the user is reduced, so that the drinking mouthfeel of the antiviral oral liquid is effectively improved.
2. According to the antiviral oral liquid with good taste, in the disinfection process, the disinfection cabinet is arranged, the movable buckle plate is arranged, when a user carries out air tightness detection and disinfection treatment on the packaged antiviral oral liquid, the user can move a large amount of antiviral oral liquid at one time by using the push-pull flatcar, the movable buckle plate clamps and fixes two sides of the push-pull flatcar by using the spring pins, so that the push-pull flatcar and the box body shell are kept in a relatively fixed state, an object on the push-pull flatcar is transferred more stably, the phenomenon that the antiviral oral liquid is scattered in the cleaning detection process is avoided, and the safety of the operation link is improved.
3. According to the antiviral oral liquid with good taste, in the disinfection process, the disinfection cabinet is arranged, the solenoid and the fixing lining plate are arranged, when a trolley filled with the antiviral oral liquid enters the disinfection cabinet, the controller enables the surface coil of the solenoid to be electrified, the iron core inside the solenoid is magnetized, and the electrified solenoid can be used for carrying out magnetic adsorption and fixation on the trolley entering the disinfection cabinet, so that the phenomenon of shaking of the antiviral oral liquid on the trolley in the spraying and cleaning process is avoided, and the stability of the antiviral oral liquid in the cleaning process is improved.
4. According to the antiviral oral liquid with good taste, in the disinfection process, the disinfection cabinet is arranged, the drainage plate and the filter box are arranged, after the finished product of the antiviral oral liquid is cleaned and disinfected, water consumed during cleaning enters the filter box through the drainage groove of the drainage plate, and after being filtered by the four layers of filter plates of the filter box, the water can be guided into the ball-shaped spray head through the flow guide pipe to perform secondary cleaning operation, so that water resources consumed during the production process are reduced, and a certain energy-saving effect is achieved.
Drawings
The invention will be further described with reference to the accompanying drawings.
FIG. 1 is a schematic view of the whole structure of the antiviral oral liquid with good taste and the sterilization cabinet in the production process thereof.
FIG. 2 is a schematic structural diagram of the antiviral oral liquid with good taste and the movable buckle plate of the sterilization cabinet in the production process of the antiviral oral liquid.
FIG. 3 is an overall structure diagram of the antiviral oral liquid with good taste and the sterilization cabinet fixing lining board in the production process thereof.
FIG. 4 is an overall structure diagram of the water circulation structure of the anti-virus oral liquid with good taste and the sterilization cabinet of the production process thereof.
FIG. 5 is a schematic structural view of an antiviral oral liquid with good taste and a sterilization shock-absorbing leg produced by the production process thereof.
In the figure: 1. a shock-absorbing pulley; 2. a limiting chute; 3. pushing and pulling the flat car; 4. a push-pull handle; 5. moving the buckle plate; 6. a shock-absorbing leg; 7. an air draft groove; 8. a stationary washer; 9. a sealing door panel; 10. a water inlet pipe; 11. a vacuum machine; 12. a spherical spray head; 13. a communicating pipe; 14. a pressure gauge; 15. an operation knob; 16. a case body shell; 17. fixing the bolt; 18. an elastic fastener; 19. a spring pin; 20. a connecting bolt head; 21. a controller; 22. fixing the lining plate; 23. a fixing ring; 24. a solenoid; 25. an upper sealing plate; 26. a filter plate; 27. a flow guide pipe; 28. a drainage groove; 29. a drainage plate; 30. a filter box; 31. an anti-slip base pad; 32. a damping spring; 33. a threaded tube head; 34. and (5) fastening the threads.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in figures 1-5, an antiviral oral liquid with good taste, every 1100ml of oral liquid is prepared from the following raw materials: 45.5g of isatis root, 8.5g of weeping forsythia, 12.5g of cablin potchouli herb, 15g of grassleaf sweelflag rhizome, 27g of gypsum, 18g of turmeric root-tuber, 35g of common anemarrhena rhizome, 13g of reed rhizome, 18g of rehmannia root, 12g of cane sugar, 9g of honey and 11g of xylitol, and the antiviral oral liquid with good taste is prepared by the following steps of:
the method comprises the following steps: putting the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root into an extraction tank, adding water, boiling and decocting the decoction pieces twice by using boiling water, wherein the time for boiling for decocting for the first time is 3.2 hours, cooling for 1.5 hours, precipitating the decoction dregs, and decocting for the second time;
step two: pouring the decocted mixture into a straight barrel extraction tank, extracting volatile oil and hair oil emulsion, pouring the residual liquid into an alcohol precipitation tank, precipitating solid residues by using the alcohol precipitation tank, filtering out liquid medicine residues after liquid medicine is precipitated, concentrating the liquid medicine to 55% by using a double-effect concentrator, adding a volatile oil inclusion compound and a proper amount of honey, cane sugar, orange essence and xylitol into the liquid medicine, and removing the bitter taste in the original liquid medicine;
step three: adjusting pH with 12% sodium hydroxide solution, filtering with filter to obtain concentrated medicinal liquid, adding water to 1100ml, mixing the liquids, bottling with oral liquid bottle filling machine, and sterilizing with sterilizing cabinet to obtain the final product.
The production process of the antiviral oral liquid with good mouthfeel comprises the following steps:
step one; putting the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root into an extraction tank, adding water, boiling and decocting the decoction pieces twice by using boiling water, wherein the time for boiling for decocting for the first time is 3.2 hours, cooling for 1.5 hours, precipitating the decoction dregs, and decocting for the second time;
step two: pouring the decocted mixture into a straight barrel extraction tank, extracting volatile oil and hair oil emulsion, pouring the residual liquid into an alcohol precipitation tank, precipitating solid residues by using the alcohol precipitation tank, filtering out liquid medicine residues after liquid medicine is precipitated, concentrating the liquid medicine to 55% by using a double-effect concentrator, adding a volatile oil inclusion compound and a proper amount of honey, cane sugar, orange essence and xylitol into the liquid medicine, and removing the bitter taste in the original liquid medicine;
step three: adjusting pH with 12% sodium hydroxide solution, filtering with filter to obtain concentrated medicinal liquid, adding water to 1100ml, mixing the liquids, bottling with oral liquid bottle filling machine, and sterilizing with sterilizing cabinet to obtain the final product.
A production process of antiviral oral liquid with good taste comprises the following steps that a sterilization cabinet in the third step comprises a box body shell 16, a fixed lining plate 22, a movable buckle plate 5 and a filter box 30, wherein a push-pull flat car 3 is installed on the outer surface of the front end of the box body shell 16, four groups of damping pulleys 1 are fixedly installed on the outer surface of the lower end of the box body shell 16, two groups of limiting chutes 2 are arranged on the inner side of the upper part of the push-pull flat car 3, and a push-pull handle 4 is fixedly installed on the outer surface of the upper end of the push-pull flat car 3;
an operation knob 15 is movably mounted on the outer surface of the front end of a box body shell 16, two groups of pressure gauges 14 are fixedly mounted on the outer surface of the front end of the box body shell 16 close to the upper portion of the operation knob 15, a sealing door plate 9 is movably mounted on the front portion of the box body shell 16, two groups of air suction grooves 7 are arranged on the inner side of the sealing door plate 9 at equal intervals, a fixing gasket 8 is fixedly mounted on the outer surface of the front end of the sealing door plate 9, four groups of ball nozzles 12 are mounted on the top of the inner side of the box body shell 16 at equal intervals, a vacuum machine 11 is fixedly mounted on the outer surface of the upper end of the box body shell 16, two groups of communicating pipes 13 are fixedly mounted on one side of the outer surface of the;
an elastic clamping piece 18 is installed at the lower part of the movable buckle plate 5, the movable buckle plate 5 and the elastic clamping piece 18 are fixedly connected through a connecting bolt head 20, spring pins 19 are fixedly installed on two sides of the connecting bolt head 20, four groups of fixing bolts 17 are installed at the lower part of the elastic clamping piece 18 in a penetrating mode, a fixing lining plate 22 is installed on the inner side of the box body shell 16, a fixing ring 23 is sleeved on the upper part of the fixing lining plate 22, five groups of solenoids 24 are installed on the inner side of the fixing ring 23, an upper sealing plate 25 is fixedly installed at the top end of the fixing lining plate 22, a filter box 30 is installed on the inner side of the bottom of the box body shell 16, a drainage plate 29 is installed at the upper part of the filter box 30, and four groups of filter plates 26 are installed on the inner side of the filter box 30 at equal intervals;
two groups of draft tubes 27 are fixedly arranged on the outer surface of one end of the filter box 30, two groups of drainage grooves 28 are arranged on the inner side of the upper part of the drainage plate 29 at equal intervals, four groups of shock-absorbing support legs 6 are fixedly arranged on the outer surface of the lower end of the box body shell 16, three groups of damping springs 32 are movably arranged on the inner sides of the shock-absorbing support legs 6, threaded pipe heads 33 are movably arranged on the upper ends of the damping springs 32, anti-skidding bottom cushions 31 are fixedly arranged on the bottoms of the shock-absorbing support legs 6, fastening threads 34 are arranged on the inner sides of the threaded pipe heads 33, two groups of water inlet pipes 10 are connected to the outer surface of one side of the box body shell 16 in a penetrating mode, and a controller 21 is arranged at the bottom of the fixed lining plate 22.
As a further scheme of the invention, the inner surface of one side of the movable buckle plate 5 is provided with a fixed clamping groove, the longitudinal movement range of the movable buckle plate 5 is zero to seven points and five centimeters, and the fixed clamping groove plays a role in fixing the movable buckle plate 5.
As a further scheme of the invention, four groups of induced fans are arranged on the inner side of the vacuum machine 11, and a dust cover is embedded in the inner side of the front end of the vacuum machine 11 and can prevent dust from entering the vacuum machine 11.
As a further scheme of the invention, two groups of limiting clamping seats are arranged in the box body shell 16, and the bottom of the box body shell 16 is of a hollow structure.
As a further scheme of the invention, two groups of filter heads are sleeved at the bottom of the flow guide pipe 27, the flow guide pipe 27 is fixed in a threaded manner, and the filter heads have a physical filtering effect on liquid discharged by the flow guide pipe 27.
As a further aspect of the present invention, the range of the rotation angle of the sealing door panel 9 is 0 to 180 °, and four sets of latches are embedded in the inner side of the sealing door panel 9 at equal intervals, and the latches perform a locking operation on the sealing door panel 9 when it is closed.
An antiviral oral liquid with good taste and a production process thereof, when in production, a user adds 11g of xylitol into the original antiviral oral liquid, when the user drinks the antiviral oral liquid, the xylitol can improve the sweetness of the antiviral oral liquid under the condition of not increasing the sugar content in the antiviral oral liquid, and simultaneously, after the user drinks the antiviral oral liquid, the oral cavity of the user is cleaned, the bitter taste in the mouth of the user is reduced, thereby effectively improving the drinking taste of the antiviral oral liquid, when the user carries out detection and cleaning operation on the antiviral oral liquid, the user pushes and pulls a push-pull handle 4, the push and pull flat wagon 3 is moved by utilizing a damping pulley 1, a large amount of packaged antiviral oral liquid is loaded through a limiting chute 2 of the push and pull flat wagon 3, and the head of the push and pull flat wagon 3 is aligned to the front part of a box body shell 16 by the user, pushing the push-pull flat car 3, enabling the movable buckle 5 to complete reset fixing operation under the action of the spring pin 19 and the connecting bolt head 20, fixing the push-pull flat car 3, avoiding displacement of the push-pull flat car 3, enabling the elastic clamping piece 18 to fix the spring pin 19 and the connecting bolt head 20, enabling a user to close the sealing door plate 9, enabling the fixing gasket 8 of the sealing door plate 9 to be attracted with the box body shell 16, rotating the operation knob 15, starting the vacuum machine 11 of the box body shell 16, enabling the operation principle of the vacuum machine 11 to be the same as that of a vacuum device DZ-660Z, discharging air in the box body shell 16 through the vacuum machine 11, detecting the sealing performance of antiviral oral liquid in the box body shell 16, increasing the temperature in the box body shell 16 by using the communicating pipe 13, carrying out high-temperature sterilization, enabling the pressure gauge 14 to display internal pressure change of the box body shell 16, and enabling the water inlet pipe 10 to be led into an external water body, the water body is sprayed out through the ball spray head 12, the sprayed water body carries out disinfection operation on the packaged antiviral oral liquid, through the arrangement of the drainage plate 29 and the filter box 30, after the finished product of the antiviral oral liquid is cleaned and disinfected, the water body consumed during cleaning enters the filter box 30 through the drainage groove 28 of the drainage plate 29, and after being filtered by the four layers of filter plates 26 of the filter box 30, the water body can be guided into the ball spray head 12 through the guide pipe 27 to carry out secondary cleaning operation, so that the water resource consumed during the production loop is reduced, a certain energy-saving effect is achieved, through the arrangement of the solenoid 24 and the fixed lining plate 22, when a trolley filled with the antiviral oral liquid enters a sterilization cabinet, the model of the controller 21 is ZM-7205A, the controller 21 enables the surface coil of the solenoid 24 to be electrified, the iron core inside the solenoid 24 is magnetized, and the solenoid 24 after being electrified can carry out magnetic adsorption and fixation on the trolley entering the sterilization cabinet, thereby avoid antiviral oral liquid on the shallow to appear rocking the phenomenon spraying the cleaning process in, increase the stability in its cleaning process, gu fixed ring 23 plays the fixed action with last shrouding 25 to solenoid 24, the screw tube head 33 of leg 6 of moving away to avoid possible earthquakes plays shock attenuation guard action, comparatively practical to the equipment operation under the damping spring 32 effect.
The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims (1)

1. A sterilization cabinet for a production process of an antiviral oral liquid with good taste is characterized in that the production process of the antiviral oral liquid is that every 1100ml of the oral liquid is prepared from the following raw materials: 45.5g of isatis root, 8.5g of weeping forsythia, 12.5g of cablin potchouli herb, 15g of grassleaf sweelflag rhizome, 27g of gypsum, 18g of turmeric root-tuber, 35g of common anemarrhena rhizome, 13g of reed rhizome, 18g of rehmannia root, 12g of cane sugar, 9g of honey and 11g of xylitol, and the antiviral oral liquid with good taste is prepared by the following steps of:
the method comprises the following steps: putting the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root into an extraction tank, adding water, boiling and decocting the decoction pieces twice by using boiling water, wherein the time for boiling for decocting for the first time is 3.2 hours, cooling for 1.5 hours, precipitating the decoction dregs, and decocting for the second time;
step two: pouring the decocted mixture into a straight barrel extraction tank, extracting volatile oil and hair oil emulsion, pouring the residual liquid into an alcohol precipitation tank, precipitating solid residues by using the alcohol precipitation tank, filtering out liquid medicine residues after liquid medicine is precipitated, concentrating the liquid medicine to 55% by using a double-effect concentrator, adding a volatile oil inclusion compound and a proper amount of honey, cane sugar, orange essence and xylitol into the liquid medicine, and removing the bitter taste in the original liquid medicine;
step three: adjusting pH with 12% sodium hydroxide solution, filtering with filter to obtain concentrated medicinal liquid, adding water to 1100ml, mixing the liquids, bottling with oral liquid bottle filling machine, and sterilizing with sterilizing cabinet to obtain oral liquid product;
the sterilization cabinet comprises a box body shell (16), a fixed lining plate (22), a movable buckle plate (5) and a filter box (30), wherein a push-pull flat car (3) is installed on the outer surface of the front end of the box body shell (16), four groups of damping pulleys (1) are fixedly installed on the outer surface of the lower end of the box body shell (16), two groups of limiting sliding grooves (2) are formed in the inner side of the upper portion of the push-pull flat car (3), and a push-pull handle (4) is fixedly installed on the outer surface of the upper end of the push-pull flat car (3);
an operating knob (15) is movably arranged on the outer surface of the front end of the box body shell (16), two groups of pressure gauges (14) are fixedly arranged on the outer surface of the front end of the box body shell (16) close to the upper part of the operation knob (15), a sealing door plate (9) is movably arranged on the front part of the box body shell (16), two groups of air draft grooves (7) are arranged on the inner side of the sealing door panel (9) at equal intervals, a fixed gasket (8) is fixedly arranged on the outer surface of the front end of the sealing door panel (9), four groups of ball nozzles (12) are arranged at the top of the inner side of the box body shell (16) at equal intervals, the outer surface of the upper end of the box body shell (16) is fixedly provided with a vacuum machine (11), and one side of the outer surface of the upper end of the box body shell (16) close to the vacuum machine (11) is fixedly provided with two groups of communicating pipes (13), the push-pull flat wagon (3) is fixedly connected with the box body shell (16) through a movable buckle plate (5);
an elastic clamping piece (18) is arranged at the lower part of the movable pinch plate (5), the movable pinch plate (5) and the elastic clamping piece (18) are fixedly connected through a connecting bolt head (20), spring pins (19) are fixedly arranged on two sides of the connecting bolt head (20), four groups of fixing bolts (17) are arranged on the lower portion of the elastic clamping piece (18) in a penetrating mode, the fixing lining plate (22) is arranged on the inner side of the box body shell (16), and the upper part of the fixed lining plate (22) is sleeved with a fixed ring (23), the inner side of the fixed ring (23) is provided with five groups of solenoids (24), an upper sealing plate (25) is fixedly arranged at the top end of the fixed lining plate (22), the filter box (30) is arranged at the inner side of the bottom of the box body shell (16), the upper part of the filter box (30) is provided with a drainage plate (29), four groups of filter plates (26) are arranged on the inner side of the filter box (30) at equal intervals;
the outer surface of one end of the filter box (30) is fixedly provided with two groups of flow guide pipes (27), the inner side of the upper part of the flow guide plate (29) is provided with two groups of flow guide grooves (28) at equal intervals, the outer surface of the lower end of the box shell (16) is fixedly provided with four groups of shock-absorbing support legs (6), the inner side of the shock-absorbing support legs (6) is movably provided with three groups of shock-absorbing springs (32), the upper ends of the shock-absorbing springs (32) are movably provided with threaded pipe heads (33), the bottom of the shock-absorbing support legs (6) is fixedly provided with an anti-skidding base (31), the inner side of each threaded pipe head (33) is provided with a fastening thread (34), the outer surface of one side of the box shell (16) is in through connection with two groups of water inlet pipes (10), and the bottom of the fixed lining plate (22) is provided with a controller (21);
a fixed clamping groove is formed in the inner surface of one side of the movable buckling plate (5), and the longitudinal movement range of the movable buckling plate (5) is zero to seven points and five centimeters;
four groups of induced fans are arranged on the inner side of the vacuum machine (11), and a dust cover is embedded in the inner side of the front end of the vacuum machine (11);
two groups of limiting clamping seats are arranged in the box body shell (16), and the bottom of the box body shell (16) is of a hollow structure;
the bottom of the flow guide pipe (27) is sleeved with two groups of filter heads, and the flow guide pipe (27) is fixed in a threaded manner;
the rotating angle range of the sealing door panel (9) is 0-180 degrees, and four groups of lock bolts are embedded into the inner side of the sealing door panel (9) at equal intervals.
CN201811385879.0A 2018-11-20 2018-11-20 Antiviral oral liquid with good taste and production process thereof Active CN109498778B (en)

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