CN109481364A - A kind of pure natural light blue lotion and the preparation method and application thereof containing liquid crystalline phase - Google Patents
A kind of pure natural light blue lotion and the preparation method and application thereof containing liquid crystalline phase Download PDFInfo
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- CN109481364A CN109481364A CN201811493943.7A CN201811493943A CN109481364A CN 109481364 A CN109481364 A CN 109481364A CN 201811493943 A CN201811493943 A CN 201811493943A CN 109481364 A CN109481364 A CN 109481364A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0295—Liquid crystals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The pure natural light blue lotion containing liquid crystalline phase that the invention discloses a kind of, including deep-sea aqueous extract magnolia obovata extract and emulsifier, grease, and the weight ratio of deep-sea water magnolia obovata extract and emulsifier, grease is 60-90:0.01-0.1:3-10:0.1-5.The present invention is by by deep-sea aqueous extract and Magnolia cortex P.E and emulsifier, grease is according to specified weight than carrying out prescription design, and it is aided with the lower alcohol of specified weight part, thickener, acid-base modifier and nonionic surfactant, pass through the coordinated of each component, the pure natural light blue emulsion matrix of liquid crystalline phase that contains being prepared is keeping skin wet, on the basis of the effect of constructing healthy skin, with pure natural light blue, containing liquid crystalline phase, microelement is provided for skin and is easily absorbed by the skin, functional component can be sustained and reach deep skin across skin, it can be widely applied to cosmetics, in hair shampoo article.
Description
Technical field
The present invention relates to traditional Chinese medicine or daily use chemicals technical field, in particular to a kind of pure natural light blue lotion containing liquid crystalline phase
And the preparation method and application thereof.
Background technique
With economic rapid development, requirement of the people to cosmetics is higher and higher, health, safely, effectively, high-tech,
Simultaneously again do not lose fashionable element cosmetics be in recent years people to cosmetics requirement.The appearance color of cosmetics is no longer
Only dull white emulsion system, healthy pure natural color increasingly become minimum requirements of the people to cosmetics, therefore, people
The raw material of cosmetics is more paid attention to, chemicals are increasingly repelled, and pure natural pure plant substance gains great popularity.
Science and technology development also make people to cosmetics science and technology more stringent requirements are proposed, be relevant to toiletries knowledge, people
More or less all know about, science and technology-oriented cosmetics are preferably to serve skin to preferably serve the mankind.With
Skin research is goed deep into, moisture-keeping functions, quickly absorbed research is more and more deep, and application of the liquid crystal in cosmetics is ground
Study carefully and just embodies.According to scientific research, firstly, liquid crystal type cosmetics can increase emulsion intercalation method, around oil droplet, deposit
In multilayered structure, this result can play the role of hindering coacervation in rheological characteristic；In addition, liquid crystal type cosmetics have enhancing moisturizing
The effect of property, glue reticular structure in water and contains the multilayered structure for being swollen water there are the multilayered structure around oil droplet, when
When being coated in skin surface, the moisture in multilayered structure is not easy to volatilize at once to have reached permanent moisturizing；In addition, liquid crystal type
Cosmetic can accomplish the sustained release of both effectiveness ingredient, and this effect is also attributed to the liquid crystal of layer structure；In addition, liquid crystal type cosmetics
And it is easier to prepare, and have salubrious skin sense.According to current scientific statistics, liquid crystal can be prepared by also having multiple companies to have been developed that
The emulsifier of type cosmetics, abbreviation liquid crystal type emulsifier, but price are more expensive and application has limitation, will not form natural face
Color.
Summary of the invention
For overcome the deficiencies in the prior art or defect, primary and foremost purpose of the invention are directed to a kind of containing the pure of liquid crystalline phase
Natural light blue lotion.
Another object of the present invention is to provide the preparation method of the above-mentioned pure natural light blue lotion containing liquid crystalline phase；
Another object of the present invention is to provide the application of the above-mentioned pure natural light blue lotion containing liquid crystalline phase.
Technical scheme is as follows:
A kind of pure natural light blue lotion containing liquid crystalline phase of the present invention, including deep-sea aqueous extract magnolia obovata extract
Object and emulsifier, grease, and the weight ratio of deep-sea aqueous extract magnolia obovata extract and emulsifier, grease is 60-90:
0.01-0.1:3-10:0.1-5.
The weight ratio for only adjusting deep-sea aqueous extract magnolia obovata extract and emulsifier, grease is 60-90:0.01-
0.1:3-10:0.1-5, the pure natural light blue lotion containing liquid crystalline phase being prepared are keeping skin wet, construct healthy skin
On the basis of the effect of skin, have it is pure natural light blue, contain liquid crystalline phase, provide microelement for skin and be easily absorbed by the skin, function
Effect ingredient can be sustained and reach deep skin across skin, can be widely applied to cosmetics, in hair shampoo article.And when deep-sea water extracts
The weight ratio of liquid magnolia obovata extract and emulsifier, grease is excessive (being greater than 60-90:0.01-0.1:3-10:0.1-5), system
Standby obtained pure natural light blue lotion, emulsifying ability are not enough easily layered, aneroid crystalline formation and higher cost；And when deep-sea water mentions
Take the weight ratio of liquid magnolia obovata extract and emulsifier, grease too small (being less than 60-90:0.01-0.1:3-10:0.1-5),
The pure natural light blue lotion being prepared, Material is more greasy, aneroid crystalline formation, and is keeping skin wet, building strong
Health skin, the microelement and functional component that provide for skin absorption effect can reduce.
Preferably, the weight ratio of the deep-sea aqueous extract magnolia obovata extract and emulsifier, grease is 75-85:
0.04-0.08:4:1-3, preferably 80:0.06:4:2.
Wherein, the emulsifier is selected from acrylic copolymer, stearine, poly alkyl alcohol ethers, polyglycereol class
One or more of；Preferably acrylic acid receives/sodium acryloyldimethyl taurate.
Wherein, it is sweet to be selected from cetanol ethylhexoate, octyl dodecanol, siloxanes, saualane, caprylic capric for the grease
One or more of oily three esters.
In addition, the pure natural light blue lotion of the present invention containing liquid crystalline phase can also include by weight 5-20
Part deionized water, 1-10 parts of lower alcohols, 0.1-2 parts of acid-base modifiers, 0.1-1 portions of nonionic surfactants.
Wherein, the lower alcohol is selected from one of glycerol, 1,3- butanediol, sorbierite, propylene glycol, pentanediol or several
Kind；The acid-base modifier is selected from one of arginine, sodium citrate, sodium hydroxide, triethanolamine, monoethanolamine or several
Kind；The nonionic surfactant is selected from Cremophor RH40, PEG-60 rilanit special, PEG-7 glycerol coconut oil
One or more of ester, PEG-400.
A kind of preparation method of the above-mentioned pure natural light blue lotion containing liquid crystalline phase, includes the following steps:
1) grease, emulsifier are mixed, stirs evenly, obtains mixture 1；
2) acid-base modifier is dispersed in deionized water and is completely dissolved；
3) Magnolia cortex P.E is dispersed in nonionic surfactant；
4) deep-sea water is added in lower alcohol according to the proportion and is stirred evenly, then it is living to be already dispersed in non-ionic surface for addition
Magnolia cortex P.E in property agent stirs evenly, and obtains mixture 2；
5) mixture 2 is added in mixture 1, and stirred evenly, until forming uniform lotion；
6) it is eventually adding the acid-base modifier decomposed completely in deionized water, is stirred evenly, adjusts pH value to skin
Skin optimum range is to get the pure natural light blue lotion containing liquid crystalline phase.
The invention also discloses the pure natural light blue lotions containing liquid crystalline phase that above-mentioned preparation method is prepared to make up
Application in product, hair shampoo article
Compared with prior art, the present invention has following excellent effect:
The present invention by by deep-sea aqueous extract and Magnolia cortex P.E and emulsifier, grease, according to specified weight ratio into
Row compounding, and it is aided with the lower alcohol, thickener, acid-base modifier and nonionic surfactant of specified weight part, pass through each group
Collaboration, the connection effect divided, the pure natural light blue lotion containing liquid crystalline phase being prepared are keeping skin wet building health
On the basis of the effect of skin, have it is pure natural light blue, contain liquid crystalline phase, provide microelement for skin and be easily absorbed by the skin,
Functional component can be sustained and reach deep skin across skin, can be widely applied to cosmetics, in hair shampoo article.
Detailed description of the invention
Fig. 1 is 1 microscope effect liquid crystal of the embodiment of the present invention；
Fig. 2 is the moisture-retaining capacity test schematic diagram of the embodiment of the present invention 1；
Fig. 3 is that the Transdermal absorption of the embodiment of the present invention 1 tests schematic diagram.
Specific embodiment
Further illustrate that the present invention, following embodiment are the preferable embodiment party of the present invention below by specific embodiment
Formula, but embodiments of the present invention are not limited by following embodiments.
The raw material that the embodiment of the present invention and comparative example use is as shown in table 1, but is not limited only to these raw materials:
Table 1
Micro- sem observation liquid crystalline phase: being made tabletting for lotion, is observed under 400 times of amplification using petrographic microscope,
It is as shown in Figure 1 to observe result.
Colour stability comparison: deep-sea aqueous extract is replaced with deionized water, while indigo pigment is added, visually observes face
Variation of the color under high/low temperature, illumination condition；Lotion is prepared using deep-sea aqueous extract, visual color is in high/low temperature, light
Variation according under the conditions of.
The data test of colour stability comparison: it weighs and waits weight emulsions, chromascope is used to carry out the measurement of Lab value.Color
Difference, Lab Value Data is inconsistent, Δ E < 1 and Δ E value is smaller, and parallel laboratory test Δ E variation less, is considered as colour stable three times
Lotion.
Material form: being placed in suitable environment, using naked eyes paired observation, is coated in skin surface, sensory feel.
Material stability: sample is placed under 50 DEG C of high temperature, 4 DEG C of low temperature, room temperature and illumination condition, is seen whether point
Layer, water-oil separating.It is not layered, non-water-oil separating is considered as and has good stability.
The test method of preservation challenge: sample is taken to dispense each 100g, one bottle of addition mixed cell, one bottle of addition mixing is very
Bacterium is respectively placed in corresponding incubator, i.e. the sample of addition bacterial suspension is placed in 30-35 DEG C of incubator, and addition fungi is outstanding
The sample of liquid is placed in 20-25 DEG C of incubator.Sample after inoculation is living by certain time interval sample detection in challenge process
Bacterium number.Sample time is set to: (0 day), 7 days, 14 days, 21 days, 28 days immediately after inoculation.Corresponding culture medium is selected when sample detection
It is detected.Detection method can refer to " checked operation regulation (yeast and mold) " and " checked operation regulation (total plate count) "
It carries out, test result is as shown in table 3.
Moisture retention: using Germany's CK keratoderma moisture content tester by test in specific region on the inside of forearm
It is required that the effect of objectively evaluating the function of moisture of skin protective layer, that is, objectively evaluate lotion, test result is as schemed using after sample
Shown in 2.
Transdermal absorption: it uses Franz diffusion cell instrument (transmission area: 1cm2 receives pool volume: 8ml)；With physiological saline
20% methanol of middle addition is passed through 37 DEG C of thermostatical circulating waters as acceptable solution；Using 7 week old nude mice skins, as simulation human body skin
Skin；After equivalent sample is added, preservative film is covered, prevents solution evaporation in diffusion cell, effect 5h, for 24 hours takes connecing for each time respectively
Certain functional component (this patent such as Magnolia cortex P.E) is measured by liquid progress HPLC and is gone out peak area or content, and test result is such as
Shown in Fig. 3.
Embodiment 1-5 and comparative example 1-9: the preparation of the pure natural light blue lotion containing liquid crystalline phase
Grease, emulsifier are mixed, stirs evenly, obtains mixture 1；Acid-base modifier is dispersed in complete in deionized water
Fully dissolved；Magnolia cortex P.E is dispersed in nonionic surfactant；Deep-sea water is added in lower alcohol according to the proportion and is stirred
Uniformly, the Magnolia cortex P.E being already dispersed in nonionic surfactant is then added to stir evenly, obtains mixture 2；It will
Mixture 2 is added in mixture 1, and stirs evenly, until forming uniform lotion；It is eventually adding complete in deionized water
The acid-base modifier decomposed entirely, stirs evenly, and adjusts pH value to skin optimum range to get pure natural light blue containing liquid crystalline phase
Lotion, test result are as shown in table 2.
The each group distribution ratio (parts by weight) and test result of table 2 embodiment 1-5 and comparative example 1-9
3 embodiment of table, 1 preservation challenge analysis detection result
Claims (8)
1. a kind of pure natural light blue lotion containing liquid crystalline phase, which is characterized in that including deep-sea aqueous extract magnolia obovata extract,
And emulsifier, grease, and the weight ratio of deep-sea aqueous extract magnolia obovata extract and emulsifier, grease is 60-90:
0.01-0.1:3-10:0.1-5.
2. the pure natural light blue lotion according to claim 1 containing liquid crystalline phase, which is characterized in that the deep-sea water mentions
Take liquid magnolia obovata extract and emulsifier, the weight ratio of grease is 75-85:0.04-0.08:4:1-3, preferably 80:
0.06:4:2.
3. the pure natural light blue lotion according to claim 1 or 2 containing liquid crystalline phase, which is characterized in that the emulsification
Agent is selected from one or more of acrylic copolymer, stearine, poly alkyl alcohol ethers, polyglycereol class；Preferably
Acrylic acid receives/sodium acryloyldimethyl taurate.
4. the pure natural light blue lotion according to claim 1 or 2 containing liquid crystalline phase, which is characterized in that the grease
Selected from one or more of cetanol ethylhexoate, octyl dodecanol, siloxanes, saualane, Miglyol 812N.
5. the pure natural light blue lotion according to claim 1-4 containing liquid crystalline phase, which is characterized in that by weight
Part meter is measured, further includes 5-20 parts of deionized waters, 1-10 parts of lower alcohols, 0.1-2 parts of acid-base modifiers, 0.1-1 parts of non-ionic surfaces
Activating agent.
6. the pure natural light blue lotion according to claim 5 containing liquid crystalline phase, which is characterized in that the lower alcohol choosing
From one or more of glycerol, 1,3- butanediol, sorbierite, propylene glycol, pentanediol；The acid-base modifier is selected from smart ammonia
One or more of acid, sodium citrate, sodium hydroxide, triethanolamine, monoethanolamine；The nonionic surfactant is selected from
One or more of Cremophor RH40, PEG-60 rilanit special, PEG-7 glyceryl cocoate, PEG-400.
7. a kind of preparation method of the pure natural light blue lotion as claimed in any one of claims 1 to 6 containing liquid crystalline phase,
It is characterized in that, includes the following steps:
1) grease, emulsifier are mixed, stirs evenly, obtains mixture 1；
2) acid-base modifier is dispersed in deionized water and is completely dissolved；
3) Magnolia cortex P.E is dispersed in nonionic surfactant；
4) deep-sea water is added in lower alcohol according to the proportion and is stirred evenly, be then added and be already dispersed in nonionic surfactant
In Magnolia cortex P.E stir evenly, obtain mixture 2；
5) mixture 2 is added in mixture 1, and stirred evenly, until forming uniform lotion；
6) it is eventually adding the acid-base modifier decomposed completely in deionized water, is stirred evenly, it is suitable to skin to adjust pH value
Suitable range is to get the pure natural light blue lotion containing liquid crystalline phase.
8. the pure natural light blue lotion containing liquid crystalline phase that preparation method as claimed in claim 7 is prepared is in cosmetics, hair washing
Application in articles.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811493943.7A CN109481364A (en) | 2018-12-07 | 2018-12-07 | A kind of pure natural light blue lotion and the preparation method and application thereof containing liquid crystalline phase |
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| CN201811493943.7A CN109481364A (en) | 2018-12-07 | 2018-12-07 | A kind of pure natural light blue lotion and the preparation method and application thereof containing liquid crystalline phase |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101143308B1 (en) * | 2011-07-26 | 2012-07-02 | 하정오 | Cosmetic composition with high moisturing and producing method thereof |
| CN106580745A (en) * | 2016-11-29 | 2017-04-26 | 广州市禾基生物科技有限公司 | Composition capable of solubilizing animal oil and application thereof, and cosmetic prepared from composition |
| CN107137241A (en) * | 2017-05-23 | 2017-09-08 | 广州市花安堂生物科技有限公司 | A kind of microemulsion spraying and preparation method thereof |
| CN108785160A (en) * | 2018-06-25 | 2018-11-13 | 广州市禾基生物科技有限公司 | A kind of transparent blue lotion of the pure natural crystal grain containing pearly-lustre or gel and the preparation method and application thereof |
-
2018
- 2018-12-07 CN CN201811493943.7A patent/CN109481364A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101143308B1 (en) * | 2011-07-26 | 2012-07-02 | 하정오 | Cosmetic composition with high moisturing and producing method thereof |
| CN106580745A (en) * | 2016-11-29 | 2017-04-26 | 广州市禾基生物科技有限公司 | Composition capable of solubilizing animal oil and application thereof, and cosmetic prepared from composition |
| CN107137241A (en) * | 2017-05-23 | 2017-09-08 | 广州市花安堂生物科技有限公司 | A kind of microemulsion spraying and preparation method thereof |
| CN108785160A (en) * | 2018-06-25 | 2018-11-13 | 广州市禾基生物科技有限公司 | A kind of transparent blue lotion of the pure natural crystal grain containing pearly-lustre or gel and the preparation method and application thereof |
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