CN109475293A - 用于在对象的深度表征中使用的系统和方法 - Google Patents

用于在对象的深度表征中使用的系统和方法 Download PDF

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Publication number
CN109475293A
CN109475293A CN201780032350.8A CN201780032350A CN109475293A CN 109475293 A CN109475293 A CN 109475293A CN 201780032350 A CN201780032350 A CN 201780032350A CN 109475293 A CN109475293 A CN 109475293A
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China
Prior art keywords
sample
light
depth
unit
image data
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Pending
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CN201780032350.8A
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English (en)
Chinese (zh)
Inventor
泽埃夫·扎勒夫斯基
哈维尔·加西亚
尼西姆·尼桑·奥扎娜
兰·卡里法
摩西·阿里·阿里尔·施瓦兹
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Con Tius Bioassay Co Ltd
ContinUse Biometrics Ltd
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Con Tius Bioassay Co Ltd
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Publication of CN109475293A publication Critical patent/CN109475293A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02094—Speckle interferometers, i.e. for detecting changes in speckle pattern
    • G01B9/02095—Speckle interferometers, i.e. for detecting changes in speckle pattern detecting deformation from original shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/16—Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/16—Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge
    • G01B11/161—Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge by interferometric means
    • G01B11/162—Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge by interferometric means by speckle- or shearing interferometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
    • G01B9/02007—Two or more frequencies or sources used for interferometric measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02094—Speckle interferometers, i.e. for detecting changes in speckle pattern
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/50—Depth or shape recovery
    • G06T7/514—Depth or shape recovery from specularities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
    • A61B5/0051—Detecting, measuring or recording by applying mechanical forces or stimuli by applying vibrations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01H—MEASUREMENT OF MECHANICAL VIBRATIONS OR ULTRASONIC, SONIC OR INFRASONIC WAVES
    • G01H9/00—Measuring mechanical vibrations or ultrasonic, sonic or infrasonic waves by using radiation-sensitive means, e.g. optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G01N2021/4711—Multiangle measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4788—Diffraction
    • G01N2021/479—Speckle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21—Polarisation-affecting properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10101—Optical tomography; Optical coherence tomography [OCT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20048—Transform domain processing
    • G06T2207/20056—Discrete and fast Fourier transform, [DFT, FFT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Radar Systems Or Details Thereof (AREA)
CN201780032350.8A 2016-05-23 2017-05-23 用于在对象的深度表征中使用的系统和方法 Pending CN109475293A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662340264P 2016-05-23 2016-05-23
US62/340,264 2016-05-23
US201662349750P 2016-06-14 2016-06-14
US62/349,750 2016-06-14
PCT/IL2017/050574 WO2017203525A1 (en) 2016-05-23 2017-05-23 System and method for use in depth characterization of objects

Publications (1)

Publication Number Publication Date
CN109475293A true CN109475293A (zh) 2019-03-15

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Country Status (6)

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US (1) US10724846B2 (enExample)
EP (1) EP3463056A4 (enExample)
JP (1) JP2019523393A (enExample)
CN (1) CN109475293A (enExample)
IL (1) IL262792B (enExample)
WO (1) WO2017203525A1 (enExample)

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CN114503000A (zh) * 2019-10-02 2022-05-13 科格尼菲博有限公司 光学神经元单元及其网络
CN115053168A (zh) * 2020-01-14 2022-09-13 Pxe 计算成像有限公司 用于物体的光学成像和测量的系统和方法
CN116368347A (zh) * 2020-08-27 2023-06-30 诺威有限公司 高吞吐量的光学计量
CN116507877A (zh) * 2020-11-20 2023-07-28 斯图加特大学 单帧斜波干涉仪

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JP6580012B2 (ja) * 2016-09-28 2019-09-25 富士フイルム株式会社 撮影画像評価装置および方法並びにプログラム
IL253862B (en) * 2017-08-06 2021-04-29 Elbit Systems Land & C4I Ltd Photoacoustic excitation sensing enhanced by cross-correlated unfocused speckle images
ES2787887T3 (es) * 2017-10-27 2020-10-19 Humboldt Univ Zu Berlin Procedimiento fotoacústico con una luz de medición que presenta una gama de longitud de onda predeterminada para determinar propiedades de una muestra no homogénea
WO2019215717A1 (en) * 2018-05-10 2019-11-14 ContinUse Biometrics Ltd. A system and method for depth flow inspection
IL261039B (en) * 2018-08-07 2020-10-29 Elbit Systems Land & C4I Ltd A two-stage system and method for sensing photoacoustic excitation
US10931881B2 (en) * 2018-09-20 2021-02-23 ContinUse Biometrics Ltd. Sample inspection utilizing time modulated illumination
US11740128B2 (en) * 2019-07-24 2023-08-29 Sanguis Corporation System and method for non-invasive measurement of analytes in vivo
EP4130652A4 (en) * 2020-04-03 2023-10-04 Xtia Ltd MEASURING DEVICE, MEASURING METHOD AND PROGRAM
US11850026B2 (en) 2020-06-24 2023-12-26 The Governing Council Of The University Of Toronto Remote portable vital signs monitoring
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DE102021208775B8 (de) * 2021-08-11 2023-01-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Verfahren zur Erkennung von Defekten an stoffschlüssigen Verbindungen
US20230296510A1 (en) * 2022-03-16 2023-09-21 Meta Platforms Technologies, Llc System and method for separating volumetric and surface scattering of optical component
CN115187644B (zh) * 2022-06-10 2025-07-29 奥比中光科技集团股份有限公司 应用于单目结构光的深度计算模型的训练方法和计算方法
CN122041752B (zh) * 2026-04-16 2026-06-30 太行国家实验室 一种可时序控制的非接触式变形的测量方法、装置、计算机设备及介质

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CN114503000A (zh) * 2019-10-02 2022-05-13 科格尼菲博有限公司 光学神经元单元及其网络
CN115053168A (zh) * 2020-01-14 2022-09-13 Pxe 计算成像有限公司 用于物体的光学成像和测量的系统和方法
CN115053168B (zh) * 2020-01-14 2024-09-06 Pxe计算成像有限公司 用于物体的光学成像和测量的系统和方法
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CN116507877A (zh) * 2020-11-20 2023-07-28 斯图加特大学 单帧斜波干涉仪

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WO2017203525A1 (en) 2017-11-30
JP2019523393A (ja) 2019-08-22
EP3463056A4 (en) 2020-07-29
EP3463056A1 (en) 2019-04-10
IL262792A (en) 2018-12-31
IL262792B (en) 2022-05-01
US20190212124A1 (en) 2019-07-11
US10724846B2 (en) 2020-07-28

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Application publication date: 20190315