CN109453104A - Light spot skin toner Essence and its preparation process - Google Patents
Light spot skin toner Essence and its preparation process Download PDFInfo
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- CN109453104A CN109453104A CN201811601590.8A CN201811601590A CN109453104A CN 109453104 A CN109453104 A CN 109453104A CN 201811601590 A CN201811601590 A CN 201811601590A CN 109453104 A CN109453104 A CN 109453104A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention discloses a kind of light spot skin toner Essence and its preparation process, the preparation process includes the following steps: that (1) weighs each raw material by weight；(2) it is 300-900r/min mixing 5-15min with revolving speed with high-speed mixer by each raw material, obtains mixture；(3) add mixture into and carry out melt blending in double screw extruder, cooling after squeezing out, dry, pelletizing to get.By research, the toner found will not only play the role of skin toner, should also protect the barrier function of skin the present invention, skin barrier function cannot be made to be destroyed instead because of the temporary moisturizing on surface；Using the honey of ecosystem as primary raw material, there is the amino acid in honey moisture-keeping function skin can be made moist；Water-soluble chitosan, the compatibilities such as arasaponin are selected, skin toner nutritive validity is strengthened, constitutes the two-in-one product of novel natural skin toner, nutrition, skin toner nutrition Essence；It is used for a long time, the delicate exquisiteness of skin, skin barrier function enhancing can be made.
Description
Technical field
The invention belongs to technical field of skin care, specifically, being related to a kind of light spot skin toner Essence and its preparation process.
Background technique
With the growth at the age of people, human skin will receive different degrees of injury, such as be exposed to seriously polluted sky
In gas, ultraviolet light irradiation or eat contaminated food etc. various factors, all can be different degrees of cause skin dehydration, it is dim
It is unglazed, follow the string etc..
Skin is the maximum organ of human body, the 5-15% of total weight percentage of liveweight, thickness because people or because of position it is different, be 0.5-
4 millimeters.Skin covers whole body, it makes various tissues in vivo and organ from physical, mechanicalness, chemically and pathogenic microorganism
Property invasion, there are two the barrier actions of aspect for skin tool, on the one hand prevent internal water, and electrolyte and other substances are lost
It loses, on the other hand organizes the intrusion of extraneous harmful substance, keep the stabilization of human internal environment, physiologically playing important protection
Function, while skin also assists in the metabolic process of human body.Skin is made of epidermis, corium and subcutaneous tissue three parts.
Epidermis is the direct part with extraneous contact and is the part for having most deep relationship with cosmetics.Epidermal thickness is only 0.2mm,
It is to be piled up to constitute by horn cell.On the inside of skin, epidermis can be divided into again basal layer, spinosity layer, stratum granulosum with
And cuticula.The metabolism of skin is constantly divided by the horn cell of basal layer, and about 28 day period is one
Bout.Cuticula has the function for keeping moisture and prevents the barrier machine that skin internal moisture is volatilized and external foreign matter immerses
Can, natural moisturizing factor, intercellular lipid, sodium hyaluronate in cuticula largely reduce, skin just will appear it is dry, coarse,
A series of problems, such as decortication.In addition, basal layer there are generate Mai Laning melanocyte, it have by Mai Laning come pair
The defensive enginery of ultraviolet light.
Skin aging by objective factors such as age, heredity other than being influenced, also by many factors such as daylight, environment, health
It influences.Excessive solarization is exposed to the sun, and is not only speeded up skin aging, is also also easy to produce pigmented spots；Seriously polluted environment is lived in for a long time
In or excessive contact to the harmful chemical substance of skin, can all make skin damage, accelerated ageing；Malnutrition, lassitude, disease
Disease is burdened with, and skin is easier to premature aging.Especially modern life pressure is big, overtime work stays up late, for a long time to computer, smoke, sleep
Sleep it is insufficient, stay in air-conditioned room for a long time, drink, excess eye-using etc. becomes life normality.According to the beautiful scientific center of Dior Christian Dior U.S.
Research, daily, each layer of skin can accumulate the largely cellular elements toxin as caused by inherent or external factor, and it is thin to will lead to skin
Born of the same parents' asphyxia, and the toxin Scavenging activity of skin itself is affected, to just produce, the colour of skin is obscure, lack gloss, tired state is showed fully
Etc. worries；The burden of skin has been aggravated, skin aging is accelerated.
Moisturizing is direct supply skin corneocyte with required moisture, moisturizing.Moisturizing is then to prevent skin
The evaporation of moisture while moisturizing, can more improve microcirculation, enhance skin wettability.Optimal moisturizing is skin and is mended
The good interaction of aquatic products.The sequence of correct moisturizing moisturizing should be: first moisturizing moisturizing again.Existing moisturizer, moisturizing
Time is shorter, at the same after a period of time moisturizing the effect of can also have a greatly reduced quality.
Skin aging is the various factors comprehensive function such as a progressive physiology course, and heredity, environment, social mentality
Result.As the improvement of people's living standards, the functional requirement to skin care item is higher and higher, has the skin care of anti-aging effects
Product also emerge one after another.Essence is a kind of skin care item of high nutrition ingredient added with concentration, according to its be formulated specific aim,
With anti-ageing, crease-resistant, compact, moisturizing, Bearberry Extract.If special profit repairs essence to the EsteLauder in the fashionable world immediately,
Sisley polywater composite essence, JasonNatural esterification C whitening anti-aging perfection Essence etc..It is added in these product compositions
A variety of concentration essence, while more preservatives are also added to, especially it is easy the preservative of sensitization, such as dibutyl hydroxy toluene
And benzyl alcohol.This toner is used for a long time, unavoidably skin is caused to damage, destroys skin barrier function.Therefore, seek
Safer, milder, more effective skin care item are very urgent.
Summary of the invention
Of the existing technology in order to solve the problems, such as, the present invention provides a kind of light spot skin toner Essence and its preparation works
Skill can reach the two-in-one expection of skin toner, nutrition；It is used for a long time, the delicate exquisiteness of skin, skin barrier function enhancing can be made.
The present invention is implemented as follows:
A kind of light spot skin toner Essence, including following raw materials: natural honey, carboxyl chitosan, notoginseng total saponin, water.
A kind of light spot skin toner Essence, the raw material including following mass percents: natural honey 3-6%, carboxyl chitosan
0.1-0.5%, notoginseng total saponin 0.01-0.05%, surplus are water.
Preferably, the natural honey is tangerine nectar, honey of lychee flowers, honey of lungan flowers, wolf's fang honey, citrus honey, loquat honey, rape
Honey, locust tree honey, clover honey, Mel Jujubae, Osmanthus forrestii honey, chaste honey, motherwort honey, at least one in mother chrysanthemum nectar, honey of various flowers
Kind.
Preferably, it is that 0.4-4% has the function of cell repair that the light spot skin toner Essence, which further includes mass percent,
Composition.
The prior art the study found that almost all of disease all there is corresponding organs or the cellular damages of tissue.Therefore,
Become the important thinking for preventing and treating various diseases to the reparation of damaging cells.Cell is one to the injury repair of itself
Ongoing extremely complex process, based on a complicated repair system.Although cell repair system is extremely complex, make
For system, usually it is made of structure, mechanism, function three parts.Structure is the material base of system.It is system operation and function hair
The basis waved and necessary condition.Relevant research achievement is integrated it is found that the material base of cell repair system is including at least following
Three classes: (1) growth factor group.Have now been found that such as epidermal growth factor (EGF), platelet-derived growth factor
(PDGF), fibroblast growth factor (FGF), hepatocyte growth factor (HGF), insulin like growth factor-1 (IGF-1),
IGF- II, LIF ELISA (LIF), nerve growth factor (NGF), oncostatinM (OSM), platelet-derived endothelium are thin
The intracellular growth factor (PDECGF), transforminggrowthfactor-α (TGF- α), vascular endothelial growth factor (VEGF), nerve growth
The factor (NGF), brain-derived neurotrophic factor (PDGF) etc. more than 40.(2) with the protein group of repair function.Comprehensive phase
Close the study found that according to the difference at the position damaged in different cells and cell, by different special reparation protein
Responsible for rehabilitation.At present, it has been found that and the reparation protein reported has the height for promoting DNA of researcher's discovery of University of Rochester
The protein s IRT6 repaired is imitated, North Carolina, USA university research personnel study the protein etc. for being known as Ku of discovery.(3)
The basic substance of other supply synthesis repair function protein, such as amino acid, peptide, nucleic acid.It is specific about cell repair system
Repair mechanism, mankind's face this further investigate.Meanwhile going deep into research, more protein of repairing will be sent out
It is existing.Functional study about cell repair system is found: (1) cell has the function of self-regeneration, there is a whole set of self-regeneration
Function system.The reparation of cellular damage is controlled by gene.It all include that can carry out quick injury repair in most cells
Gene.(2) directly exercising and repairing the substance of damage is the various protein with repair function, is synthesized by special damage
Revision points control.(3) cell can lose the ability for repairing itself with the aging of itself and constantly, and the aging of cell makes it certainly
The repair system of body finally loses function, leads to the decline of function of organization and the increase of Tumor incidence.(4) from cellular level
From the point of view of, the reparation of cellular damage is mainly the reproducibility reparation of cell.What is wherein played a crucial role is growth factor.(5) with
Cell senescence, the ability decline of DNA plerosis and the horizontal reduction of protein involved in repair process occur simultaneously.
(6) equally, the reproducibility repair ability of cell is as its aging is also faded until disappearing.For example people is in Children and teenager
Tissue regeneration ability is strong, and wound healing is fast；The elderly's tissue regeneration ability is weak, and healing is slow.
The composition with cell repair function is to take teenage mammal whole, and anatomical isolation goes out internal organ, obtains
Adipose tissue is removed to internal organ and non-visceral tissue, and by obtained non-visceral tissue, is then gone out by broken, enzymatic hydrolysis, virus
Refrigerated centrifuge after work, takes intermediate fluid；Intermediate fluid is obtained through ultrafiltration, degerming again.The preferably described group with cell repair function
Object is closed the preparation method comprises the following steps: (1) takes teenage mammal whole, anatomical isolation goes out internal organ, obtains internal organ and non-visceral tissue, will
Obtained non-visceral tissue removal adipose tissue, the mammal is pig, ox or sheep；(2) with it is sterile, without heat source water to step
Suddenly the internal organ and non-visceral tissue that (1) obtains are rinsed respectively；(3) internal organ respectively obtained step (2) and non-visceral group
Knit and successively carry out tissue rubbing and clasmatosis, until material grain diameter be not more than 2 μm, obtain internal organ homogenate and it is non-visceral
Homogenate；(4) by non-visceral homogenate that step (3) obtains with water for injection by 1:(2-5) weight ratio mix homogenate, then
To homogenate in by zymolyte concentration 0.5-5%w/w pancreatin or trypsase is added, in 40-60 DEG C hydrolysis 1-6 hours, then pass through
Non-visceral enzymolysis liquid is obtained after enzyme deactivation；(5) the non-visceral enzymatic hydrolysis that step (4) obtain is added in the internal organ homogenate that step (3) obtains
In liquid, it is uniformly mixed, obtains mixed enzymolysis liquid；(6) add in the mixed enzymolysis liquid that step (5) obtains by 0.09-0.15mol/L
Enter sodium chloride, holding 0.5-3 hours of 25-50 DEG C of constant temperature obtains the molten mixture of salt；(7) the molten mixture of salt for obtaining step (6)
It is virus inactivated rear refrigerated centrifuge, takes intermediate fluid；Intermediate fluid obtains described repairing with cell again through ultrafiltration, bacteria removing
The composition of multiple function.The preferred mammal embryo of teenage mammal or neonatal mammals.Preferably, described
The preferred pig of mammal, ox or sheep.Further, the composition with cell repair function specifically can be according to application
Number for 201310369405.8 Chinese patent shown in method preparation.
Preferably, the light spot skin toner Essence further includes the jasmine flower extract that mass percent is 0.4-4%.
The jasmine flower extract the preparation method comprises the following steps: the new fresh jasmine piece of picking is uniformly spread out into 2-8cm thickness,
Temperature is 25-45 DEG C, and to air-dry to water content be 8-15wt%, and the jasmine flower after air-drying crushed 10-50 mesh, obtains powder
Jasmine after broken；The bacterium solution of smashed jasmine flower weight 8-15% is uniformly sprayed to smashed Jasmine, then
It is even to spread into 15-20cm thickness out, it is sent out under conditions of temperature is 28-35 DEG C, air humidity 55-70%, oxygen content are 35-45%
Ferment 4-10d, the Jasmine after being fermented；Take fermentation after Jasmine, water be in mass ratio 1:(15-25) mixing after in temperature
It is that 25-45kHz carries out ultrasonic extraction 50-70min for 50-70 DEG C, ultrasonic power 200-400W, supersonic frequency, uses 200-800
Mesh filter-cloth filtering obtains a filter residue and first-time filtrate；Filter residue, glycal, volume fraction 65-75% ethanol water are pressed
Mass ratio is 1:(0.005-0.03): (15-25) mixing after temperature be 50-70 DEG C, ultrasonic power 200-400W, supersonic frequency
Rate carries out ultrasonic extraction 40-60min for 25-45kHz and obtains secondary filter residue and secondary filtrate with 200-800 mesh filter-cloth filtering；
Merge first-time filtrate and secondary filtrate, then temperature is 50-65 DEG C, absolute pressure is that 0.005-0.02MPa is concentrated in vacuo to original
The 5-20% of volume, obtains concentrate；0.1-0.5 μm of polypropylene filter of concentrate is filtered, jasmine flower extract is obtained.
The glycal is at least one of D- glucal, acetylation malt glycal.Further, the glycal is D-
Glucal, acetylation malt glycal are 1:(0.2-0.3 in mass ratio) mixture.
The bacterium solution the preparation method comprises the following steps: aloe is squeezed the juice with juice extractor, then use 200-800 mesh filter-cloth filtering,
Obtain asparagus juice；In mass ratio it is 1:(1-2 by aspergillus niger, bacillus coagulans, asparagus juice, water): (45-55): (19000-
21000) it is uniformly mixed, obtains bacterium solution.Up to the present, extracting and developing, identification and assay go out to change from aloe plant
Study several hundred kinds of part or more, such as aloin, cuspidatin, hexose, macromolecule polysaccharide body, aloe pavilion, aloe are mould soft, also
The compositions such as the necessary amino acid of a variety of human bodies, minerals, microelement, various vitamins and biostimulant.Glycal has anti-
Virus, anti-inflammation and sterilization, wound reparation, the function of removing free radical.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 45-55wt% of water to be uniformly mixed, stands 4-7h, be with revolving speed
3000-5000r/min is centrifuged 4-10min, takes intermediate liquid, with 0.1-0.5 μm of membrane filtration, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 0.5-1.5h, with 2-5 μm of membrane filtration, then
Notoginseng total saponin is added to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 500-1000r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added to hydromel
In, the addition speed of the carboxyl chitosan saponin mixed liquor be 0.01-0.1g/s to get.
Preferably, the preparation process of the light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 45-55wt% of water to be uniformly mixed, stands 4-7h, be with revolving speed
3000-5000r/min is centrifuged 4-10min, takes intermediate liquid, with 0.1-0.5 μm of membrane filtration, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 0.5-1.5h, with 2-5 μm of membrane filtration, then
Notoginseng total saponin is added to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 500-1000r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added to hydromel
In, the addition speed of the carboxyl chitosan saponin mixed liquor is 0.01-0.1g/s, and carboxyl chitosan saponin mixed liquor has been added
The composition with cell repair function is added after finishing, jasmine flower extract continues to be that 500-1000r/min stirs 5- with revolving speed
15min to get.
The application method of above-mentioned light spot skin toner Essence can be to use face cleaning product cleaning cotton face, emphasis free wool
Position is concentrated in hole, and clear water is cleaned after massage skin 1 minute in a manner of looping, and smears light spot skin toner Essence.
The present invention has following technical effect that
1, by research, the toner found will not only play the role of skin toner, should also protect the barrier function of skin,
Skin barrier function cannot be made to be destroyed instead because of the temporary moisturizing on surface.
2, it has selected using the honey of ecosystem as primary raw material.There is amino acid in honey moisture-keeping function can moisten skin
Pool；Wherein enzyme material abundant has natural antibacterial action again, and abundant vitamins and amino acids can have skin again
Imitate nutrition protection, can booster action in spot, acne etc..However, pollen, high molecular saccharide compound in honey and other
Miscellany substance, but be easy to cause skin hypersensitivity to react, or even cause small pox etc..Therefore, to the purifying of natural honey, removal has
Evil substance is the key that honey is applied to skin care item.Meanwhile single honey is powerful not enough to the defencive function of skin, therefore
Need its skin care effect of the cooperation competence exertion of other materials.
3, the compatibilities such as ecosystem honey effect substance after selection purification and water-soluble chitosan, arasaponin, strengthen
Skin toner nutritive validity constitutes the two-in-one product of novel natural skin toner, nutrition, skin toner nutrition Essence.
4, the application of the present invention light spot skin toner Essence the result shows that, product can reach two-in-one pre- of skin toner, nutrition really
Phase.It is used for a long time, the delicate exquisiteness of skin, skin barrier function enhancing can be made.
Specific embodiment
The present invention is further described below by way of specific embodiment, but the present invention is not limited only to following embodiment.?
It in the scope of the present invention or is not departing from the contents of the present invention, in spirit and scope, the present invention is suitably modified, is replaced
The identical component of effect, it will become apparent to those skilled in the art that they are considered as including of the invention
Within the scope of.
Embodiment is raw materials used as follows:
The acacia honey (also known as locust tree honey) that acacia honey provides for Fujian Shenfeng Science And Technology Development Co., Ltd., collecting season:
Spring, source area: Fujian.
Carboxyl chitosan provides for Zhejiang golden shell medicine company limited liability company, rank: excellent pure grade GR, carboxylation degree >=60%,
Product specification: sheet.
Notoginseng total saponin consolidates Biotechnology Co., Ltd by Shaanxi and provides, content: 80%, appearance: buff powder mentions
Fetch source: for the drying cauline leaf of panax araliaceae plant pseudo-ginseng, the specific place of production is Yunnan mountain of papers, and notoginseng haulm shines
Dry raw material.
Composition with cell repair function is according to embodiment 1 in the Chinese patent application No. is 201310369405.8
Shown method preparation.
D- glucal, No. CAS: 13265-84-4.
Juice extractor is the fruit juice extractor that Da Ruibao Food Machinery Co., Ltd. in Shanghai provides, model: DRB-0.5T.
Aloe is aloe barbadensis Miller, Classification system: Aloe vera L.Aloe barbadensis miller.
Bacillus coagulans are provided by Jinan Meng Shi great achievement Chemical Co., Ltd., model: powder, gemma number: 20,000,000,000/
Gram.
Aspergillus niger is the aspergillus niger that Shandong Changtai Biotechnology Co., Ltd provides, model: SY4006, spore content: 50
Hundred million/gram.
Jasmine produces Jasmine by Hengxian County.
Acetylation malt glycal is according to method system shown in embodiment 3 in the Chinese patent application No. is 201010281671.1
It is standby.
Embodiment 1
Light spot skin toner Essence, the raw material including following mass percents: natural honey 4.5%, carboxyl chitosan
0.25%, notoginseng total saponin 0.025%, surplus are water.
The natural honey is acacia honey.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 50wt% of water to be uniformly mixed, stands 5h, be 5000r/ with revolving speed
Min is centrifuged 5min, takes intermediate liquid, is filtered with 0.22 μm of polypropylene filter, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 1h, filtered with 3 μm of polypropylene filters, then plus
Enter notoginseng total saponin to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 600r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, it is described
The addition speed of carboxyl chitosan saponin mixed liquor is 0.02g/s to get light spot skin toner Essence.
Embodiment 2
Light spot skin toner Essence, the raw material including following mass percents: natural honey 4.5%, carboxyl chitosan
0.25%, notoginseng total saponin 0.025%, the composition 1.5% with cell repair function, surplus is water.
The natural honey is acacia honey.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 50wt% of water to be uniformly mixed, stands 5h, be 5000r/ with revolving speed
Min is centrifuged 5min, takes intermediate liquid, is filtered with 0.22 μm of polypropylene filter, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 1h, filtered with 3 μm of polypropylene filters, then plus
Enter notoginseng total saponin to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 600r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, it is described
The addition speed of carboxyl chitosan saponin mixed liquor is 0.02g/s, and tool is added after being added in carboxyl chitosan saponin mixed liquor
Having the composition of cell repair function to continue is that 600r/min stirs 10min to get light spot skin toner Essence with revolving speed.
Embodiment 3
Light spot skin toner Essence, the raw material including following mass percents: natural honey 4.5%, carboxyl chitosan
0.25%, notoginseng total saponin 0.025%, the composition 1.5% with cell repair function, jasmine flower extract 2.5%, surplus
For water.
The natural honey is acacia honey.
The jasmine flower extract the preparation method comprises the following steps: the new fresh jasmine piece of picking is uniformly spread out into 5cm thickness, in temperature
It is 10wt% that degree, which air-dries for 35 DEG C to water content, and the jasmine flower after air-drying crushed 20 meshes, obtain smashed jasmine
Flower；The bacterium solution that smashed jasmine flower weight 12% is uniformly sprayed to smashed Jasmine, then uniformly spreads into 18cm out
Thickness, ferment 7d under conditions of temperature is 30 DEG C, air humidity 60%, oxygen content are 40%, the Jasmine after being fermented；
Jasmine, water after taking fermentation are after 1:20 mixing temperature is 60 DEG C, ultrasonic power 300W, supersonic frequency are in mass ratio
40kHz carries out ultrasonic extraction 60min, is filtered with 600 mesh nylon filtering cloths, obtains a filter residue and first-time filtrate；By a filter residue,
Glycal, 70% ethanol water of volume fraction are after 1:0.012:20 mixing temperature is 60 DEG C, ultrasonic power is in mass ratio
300W, supersonic frequency are that 40kHz carries out ultrasonic extraction 50min, are filtered with 600 mesh nylon filtering cloths, obtain secondary filter residue and secondary
Filtrate；Merge first-time filtrate and secondary filtrate, then temperature is 60 DEG C, absolute pressure is that 0.01MPa is concentrated in vacuo to original volume
10%, obtain concentrate；0.22 μm of polypropylene filter of concentrate is filtered, jasmine flower extract is obtained.
The glycal is D- glucal.
The bacterium solution the preparation method comprises the following steps: by aspergillus niger, bacillus coagulans, water be in mass ratio 1:2:20050 mix
Uniformly, bacterium solution is obtained.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 50wt% of water to be uniformly mixed, stands 5h, be 5000r/ with revolving speed
Min is centrifuged 5min, takes intermediate liquid, is filtered with 0.22 μm of polypropylene filter, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 1h, filtered with 3 μm of polypropylene filters, then plus
Enter notoginseng total saponin to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 600r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, it is described
The addition speed of carboxyl chitosan saponin mixed liquor is 0.02g/s, and tool is added after being added in carboxyl chitosan saponin mixed liquor
Having the composition of cell repair function, jasmine flower extract to continue is that 600r/min stirs 10min to get light spot skin toner with revolving speed
Essence.
Embodiment 4
Light spot skin toner Essence, the raw material including following mass percents: natural honey 4.5%, carboxyl chitosan
0.25%, notoginseng total saponin 0.025%, the composition 1.5% with cell repair function, jasmine flower extract 2.5%, surplus
For water.
The natural honey is acacia honey.
The jasmine flower extract the preparation method comprises the following steps: the new fresh jasmine piece of picking is uniformly spread out into 5cm thickness, in temperature
It is 10wt% that degree, which air-dries for 35 DEG C to water content, and the jasmine flower after air-drying crushed 20 meshes, obtain smashed jasmine
Flower；The bacterium solution that smashed jasmine flower weight 12% is uniformly sprayed to smashed Jasmine, then uniformly spreads into 18cm out
Thickness, ferment 7d under conditions of temperature is 30 DEG C, air humidity 60%, oxygen content are 40%, the Jasmine after being fermented；
Jasmine, water after taking fermentation are after 1:20 mixing temperature is 60 DEG C, ultrasonic power 300W, supersonic frequency are in mass ratio
40kHz carries out ultrasonic extraction 60min, is filtered with 600 mesh nylon filtering cloths, obtains a filter residue and first-time filtrate；By a filter residue,
Glycal, 70% ethanol water of volume fraction are after 1:0.012:20 mixing temperature is 60 DEG C, ultrasonic power is in mass ratio
300W, supersonic frequency are that 40kHz carries out ultrasonic extraction 50min, are filtered with 600 mesh nylon filtering cloths, obtain secondary filter residue and secondary
Filtrate；Merge first-time filtrate and secondary filtrate, then temperature is 60 DEG C, absolute pressure is that 0.01MPa is concentrated in vacuo to original volume
10%, obtain concentrate；0.22 μm of polypropylene filter of concentrate is filtered, jasmine flower extract is obtained.
The glycal is D- glucal.
The bacterium solution the preparation method comprises the following steps: aloe is squeezed the juice with juice extractor, then filtered with 600 mesh nylon filtering cloths,
Obtain asparagus juice；Aspergillus niger, bacillus coagulans, asparagus juice, water are uniformly mixed in mass ratio for 1:2:50:20000, obtained
Bacterium solution.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 50wt% of water to be uniformly mixed, stands 5h, be 5000r/ with revolving speed
Min is centrifuged 5min, takes intermediate liquid, is filtered with 0.22 μm of polypropylene filter, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 1h, filtered with 3 μm of polypropylene filters, then plus
Enter notoginseng total saponin to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 600r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, it is described
The addition speed of carboxyl chitosan saponin mixed liquor is 0.02g/s, and tool is added after being added in carboxyl chitosan saponin mixed liquor
Having the composition of cell repair function, jasmine flower extract to continue is that 600r/min stirs 10min to get light spot skin toner with revolving speed
Essence.
Embodiment 5
Light spot skin toner Essence, the raw material including following mass percents: natural honey 4.5%, carboxyl chitosan
0.25%, notoginseng total saponin 0.025%, the composition 1.5% with cell repair function, jasmine flower extract 2.5%, surplus
For water.
The natural honey is acacia honey.
The jasmine flower extract the preparation method comprises the following steps: the new fresh jasmine piece of picking is uniformly spread out into 5cm thickness, in temperature
It is 22wt% that degree, which air-dries for 35 DEG C to water content, and the jasmine flower after air-drying crushed 20 meshes, obtain smashed jasmine
Flower；Take smashed Jasmine, water in mass ratio and be after 1:20 mixing temperature be 60 DEG C, ultrasonic power 300W, supersonic frequency
Rate is that 40kHz carries out ultrasonic extraction 60min, is filtered with 600 mesh nylon filtering cloths, obtains a filter residue and first-time filtrate；It will be primary
Filter residue, glycal, 70% ethanol water of volume fraction be in mass ratio after 1:0.012:20 mixing temperature be 60 DEG C, ultrasonic function
Rate is 300W, supersonic frequency be 40kHz carry out ultrasonic extraction 50min, with 600 mesh nylon filtering cloths filter, obtain secondary filter residue and
Secondary filtrate；Merge first-time filtrate and secondary filtrate, then temperature is 60 DEG C, absolute pressure is that 0.01MPa is concentrated in vacuo to original
The 10% of volume, obtains concentrate；0.22 μm of polypropylene filter of concentrate is filtered, jasmine flower extract is obtained.
The glycal is D- glucal.
The bacterium solution the preparation method comprises the following steps: aloe is squeezed the juice with juice extractor, then filtered with 600 mesh nylon filtering cloths,
Obtain asparagus juice；Aspergillus niger, bacillus coagulans, asparagus juice, water are uniformly mixed in mass ratio for 1:2:50:20000, obtained
Bacterium solution.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 50wt% of water to be uniformly mixed, stands 5h, be 5000r/ with revolving speed
Min is centrifuged 5min, takes intermediate liquid, is filtered with 0.22 μm of polypropylene filter, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 1h, filtered with 3 μm of polypropylene filters, then plus
Enter notoginseng total saponin to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 600r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, it is described
The addition speed of carboxyl chitosan saponin mixed liquor is 0.02g/s, and tool is added after being added in carboxyl chitosan saponin mixed liquor
Having the composition of cell repair function, jasmine flower extract to continue is that 600r/min stirs 10min to get light spot skin toner with revolving speed
Essence.
Embodiment 6
Light spot skin toner Essence, the raw material including following mass percents: natural honey 4.5%, carboxyl chitosan
0.25%, notoginseng total saponin 0.025%, the composition 1.5% with cell repair function, jasmine flower extract 2.5%, surplus
For water.
The natural honey is acacia honey.
The jasmine flower extract the preparation method comprises the following steps: the new fresh jasmine piece of picking is uniformly spread out into 5cm thickness, in temperature
It is 10wt% that degree, which air-dries for 35 DEG C to water content, and the jasmine flower after air-drying crushed 20 meshes, obtain smashed jasmine
Flower；The bacterium solution that smashed jasmine flower weight 12% is uniformly sprayed to smashed Jasmine, then uniformly spreads into 18cm out
Thickness, ferment 7d under conditions of temperature is 30 DEG C, air humidity 60%, oxygen content are 40%, the Jasmine after being fermented；
Jasmine, water after taking fermentation are after 1:20 mixing temperature is 60 DEG C, ultrasonic power 300W, supersonic frequency are in mass ratio
40kHz carries out ultrasonic extraction 60min, is filtered with 600 mesh nylon filtering cloths, obtains a filter residue and first-time filtrate；By a filter residue,
Glycal, 70% ethanol water of volume fraction are after 1:0.012:20 mixing temperature is 60 DEG C, ultrasonic power is in mass ratio
300W, supersonic frequency are that 40kHz carries out ultrasonic extraction 50min, are filtered with 600 mesh nylon filtering cloths, obtain secondary filter residue and secondary
Filtrate；Merge first-time filtrate and secondary filtrate, then temperature is 60 DEG C, absolute pressure is that 0.01MPa is concentrated in vacuo to original volume
10%, obtain concentrate；0.22 μm of polypropylene filter of concentrate is filtered, jasmine flower extract is obtained.
The glycal is acetylation malt glycal.
The bacterium solution the preparation method comprises the following steps: aloe is squeezed the juice with juice extractor, then filtered with 600 mesh nylon filtering cloths,
Obtain asparagus juice；Aspergillus niger, bacillus coagulans, asparagus juice, water are uniformly mixed in mass ratio for 1:2:50:20000, obtained
Bacterium solution.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 50wt% of water to be uniformly mixed, stands 5h, be 5000r/ with revolving speed
Min is centrifuged 5min, takes intermediate liquid, is filtered with 0.22 μm of polypropylene filter, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 1h, filtered with 3 μm of polypropylene filters, then plus
Enter notoginseng total saponin to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 600r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, it is described
The addition speed of carboxyl chitosan saponin mixed liquor is 0.02g/s, and tool is added after being added in carboxyl chitosan saponin mixed liquor
Having the composition of cell repair function, jasmine flower extract to continue is that 600r/min stirs 10min to get light spot skin toner with revolving speed
Essence.
Embodiment 7
Light spot skin toner Essence, the raw material including following mass percents: natural honey 4.5%, carboxyl chitosan
0.25%, notoginseng total saponin 0.025%, the composition 1.5% with cell repair function, jasmine flower extract 2.5%, surplus
For water.
The natural honey is acacia honey.
The jasmine flower extract the preparation method comprises the following steps: the new fresh jasmine piece of picking is uniformly spread out into 5cm thickness, in temperature
It is 10wt% that degree, which air-dries for 35 DEG C to water content, and the jasmine flower after air-drying crushed 20 meshes, obtain smashed jasmine
Flower；The bacterium solution that smashed jasmine flower weight 12% is uniformly sprayed to smashed Jasmine, then uniformly spreads into 18cm out
Thickness, ferment 7d under conditions of temperature is 30 DEG C, air humidity 60%, oxygen content are 40%, the Jasmine after being fermented；
Jasmine, water after taking fermentation are after 1:20 mixing temperature is 60 DEG C, ultrasonic power 300W, supersonic frequency are in mass ratio
40kHz carries out ultrasonic extraction 60min, is filtered with 600 mesh nylon filtering cloths, obtains a filter residue and first-time filtrate；By a filter residue,
Glycal, 70% ethanol water of volume fraction are after 1:0.012:20 mixing temperature is 60 DEG C, ultrasonic power is in mass ratio
300W, supersonic frequency are that 40kHz carries out ultrasonic extraction 50min, are filtered with 600 mesh nylon filtering cloths, obtain secondary filter residue and secondary
Filtrate；Merge first-time filtrate and secondary filtrate, then temperature is 60 DEG C, absolute pressure is that 0.01MPa is concentrated in vacuo to original volume
10%, obtain concentrate；0.22 μm of polypropylene filter of concentrate is filtered, jasmine flower extract is obtained.
The glycal is D- glucal, acetylation malt glycal is the mixture of 1:0.25 in mass ratio.
The bacterium solution the preparation method comprises the following steps: aloe is squeezed the juice with juice extractor, then filtered with 600 mesh nylon filtering cloths,
Obtain asparagus juice；Aspergillus niger, bacillus coagulans, asparagus juice, water are uniformly mixed in mass ratio for 1:2:50:20000, obtained
Bacterium solution.
The preparation process of above-mentioned light spot skin toner Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 50wt% of water to be uniformly mixed, stands 5h, be 5000r/ with revolving speed
Min is centrifuged 5min, takes intermediate liquid, is filtered with 0.22 μm of polypropylene filter, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 1h, filtered with 3 μm of polypropylene filters, then plus
Enter notoginseng total saponin to be uniformly mixed, obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 600r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, it is described
The addition speed of carboxyl chitosan saponin mixed liquor is 0.02g/s, and tool is added after being added in carboxyl chitosan saponin mixed liquor
Having the composition of cell repair function, jasmine flower extract to continue is that 600r/min stirs 10min to get light spot skin toner with revolving speed
Essence.
Test case 1
Performance of keeping humidity test is carried out to the light spot skin toner Essence of embodiment preparation.Specific test result is shown in Table 1.
70 people of women's health subject is selected, is randomly divided into 7 groups, every group of 10 people.
Subject's is included in standard:
(1) age is between 25~35 years old；
(2) subject is without any dermatopathy；
(3) recipient site skin is without exception；
(4) recipient site does not smear the external preparations such as any moisturizing cosmetic and any drug.
Usage: select left and right inner forearm as test zone.Subject washes with water forearm and bends side before testing, and on a left side
The square Experimental Area that 2cm × 2cm size positional symmetry is marked on right forearm, using left arm as the test section for smearing experiment product
Light spot skin toner Essence 0.4g is uniformly applied to subject's left arm test zone by domain, is sky with the corresponding symmetrical region of right arm
White control, once in the morning and once at night.After a week, the test of hydration rate is carried out.
Hydration rate is measured using capacitance method: using skin capacitance tester (Beijing Jin Hongfan commerce and trade Co., Ltd
There is provided, model Corneometer CM 825PC) each experiment position of test, it is repeated 5 times respectively, obtains its average value.It surveys
The value for trying region is test value, and the value of the corresponding symmetrical region of right arm is blank value, hydration rate (%)=(test value-blank
Value)/blank value × 100.Numerical value is higher, shows that sample moisture-retention function of skin is better.
The personnel of each experimental group constitute composition distribution and moisture content of skin (P > 0.05) difference without statistics in skin type
Meaning is learned, is comparable.Test front and back, each group skin hydration rate are compared, and P < 0.05, difference has statistical significance.
Table 1: performance of keeping humidity test result table
| Hydration rate (%) | |
| Embodiment 1 | 65 |
| Embodiment 2 | 67 |
| Embodiment 3 | 74 |
| Embodiment 4 | 78 |
| Embodiment 5 | 71 |
| Embodiment 6 | 77 |
| Embodiment 7 | 83 |
Test case 2
The removing free radical performance for the light spot skin toner Essence that embodiment is prepared is tested.Specific test result
It is shown in Table 2.
The measurement of free radical resisting, using DPPH method: DPPH is accurately weighed, the solution of 0.2mmol/L DPPH is configured to, in
Brown bottle is protected from light cryo-conservation.Light spot skin toner Essence sample is diluted to 10mg/mL with deionized water, obtains sample liquid.It takes
2mL sample liquid is uniformly mixed in 2mL, 0.2mmol/L DPPH solution in test tube, is added, and is protected from light after standing 30min, uses at room temperature
Ultraviolet specrophotometer UV-2000 (You Nike (Shanghai) limited instrument company) measures absorbance value at 517nm, is calculated as Ai, together
When measurement 2mL sample liquid add 2mL dehydrated alcohol, be protected from light after standing 30min at room temperature, it is (outstanding with ultraviolet specrophotometer UV-2000
Ni Ke (Shanghai) limited instrument company) measurement absorbance value at 517nm, it is calculated as Aj and 2mL, 0.2mmol/L DPPH is molten
Liquid adds 2mL distilled water to stand, and is existed with ultraviolet specrophotometer UV-2000 (You Nike (Shanghai) limited instrument company) measurement
Absorbance value at 517nm, is calculated as Ac.Each sample test is averaged three times, and sample presses the clearance rate of DPPH free radical
Formula calculates: DPPH free radical scavenging activity=[1- (Ai-Aj)/Ac] × 100%.
Table 2: free radical the performance test results table is removed
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe
The personage for knowing this technology all without departing from the spirit and scope of the present invention, carries out modifications and changes to above-described embodiment.Cause
This, institute is complete without departing from the spirit and technical ideas disclosed in the present invention by those of ordinary skill in the art such as
At all equivalent modifications or change, should be covered by the claims of the present invention.
Claims (10)
1. a kind of light spot skin toner Essence, which is characterized in that including following raw materials: the total soap of natural honey, carboxyl chitosan, Radix Notoginseng
Glucoside, water.
2. a kind of light spot skin toner Essence, which is characterized in that the raw material including following mass percents: natural honey 3-6%, carboxylic
Change chitosan 0.1-0.5%, notoginseng total saponin 0.01-0.05%, surplus is water.
3. light spot skin toner Essence as claimed in claim 2, which is characterized in that the natural honey is tangerine nectar, honey of lychee flowers, dragon
Eye honey, wolf's fang honey, citrus honey, loquat honey, rape honey, locust tree honey, clover honey, Mel Jujubae, Osmanthus forrestii honey, chaste honey, benefit are female
At least one of careless honey, mother chrysanthemum nectar, honey of various flowers.
4. light spot skin toner Essence as claimed in claim 2, which is characterized in that the light spot skin toner Essence, further includes quality
Percentage is the composition with cell repair function of 0.4-4%.
5. light spot skin toner Essence as claimed in claim 4, which is characterized in that the composition with cell repair function is
Take teenage mammal whole, anatomical isolation goes out internal organ, obtains internal organ and non-visceral tissue, and the non-visceral tissue that will be obtained
Adipose tissue is removed, then by refrigerated centrifuge after broken, enzymatic hydrolysis, inactivation of virus, takes intermediate fluid；Intermediate fluid again through ultrafiltration, remove
Bacterium obtains.
6. light spot skin toner Essence as claimed in claim 4, which is characterized in that the light spot skin toner Essence, further includes quality
Percentage is the jasmine flower extract of 0.4-4%.
7. light spot skin toner Essence as claimed in claim 6, which is characterized in that the jasmine flower extract the preparation method comprises the following steps:
The new fresh jasmine piece of picking is uniformly spread out into 2-8cm thickness, being 25-45 DEG C in temperature, to air-dry to water content be 8-15wt%,
Jasmine flower after air-drying be crushed into 10-50 mesh, obtain smashed Jasmine；It is uniformly sprayed to smashed Jasmine
Then the bacterium solution of smashed jasmine flower weight 8-15% uniformly spreads into 15-20cm thickness out, be 28-35 DEG C, air in temperature
Humidity is 55-70%, oxygen content is fermented under conditions of being 35-45% 4-10d, the Jasmine after being fermented；After taking fermentation
Jasmine, water are 1:(15-25 in mass ratio) mixing after temperature be 50-70 DEG C, ultrasonic power 200-400W, supersonic frequency
Ultrasonic extraction 50-70min, which is carried out, for 25-45kHz obtains a filter residue and first-time filtrate with 200-800 mesh filter-cloth filtering；It will
Filter residue, glycal, volume fraction 65-75% ethanol water are 1:(0.005-0.03 in mass ratio): after (15-25) mixing
Temperature be 50-70 DEG C, ultrasonic power 200-400W, supersonic frequency be 25-45kHz carry out ultrasonic extraction 40-60min, use
200-800 mesh filter-cloth filtering, obtains secondary filter residue and secondary filtrate；Merge first-time filtrate and secondary filtrate, then in temperature is 50-
65 DEG C, absolute pressure be that 0.005-0.02MPa is concentrated in vacuo to the 5-20% of original volume, obtain concentrate；Concentrate is used
0.1-0.5 μm of polypropylene filter filtering, obtains jasmine flower extract.
8. light spot skin toner Essence as claimed in claim 7, which is characterized in that the glycal is D- glucal, acetylation wheat
At least one of bud glycal；The bacterium solution the preparation method comprises the following steps: aloe is squeezed the juice with juice extractor, then use 200-800
Mesh filter-cloth filtering, obtains asparagus juice；In mass ratio it is 1:(1-2 by aspergillus niger, bacillus coagulans, asparagus juice, water): (45-
55): (19000-21000) is uniformly mixed, and obtains bacterium solution.
9. the preparation process of light spot skin toner Essence as described in Claims 2 or 3, which comprises the following steps:
(1) it takes natural honey to be added in the water of the total dosage 45-55wt% of water to be uniformly mixed, stands 4-7h, be 3000- with revolving speed
5000r/min is centrifuged 4-10min, takes intermediate liquid, with 0.1-0.5 μm of membrane filtration, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 0.5-1.5h and added with 2-5 μm of membrane filtration
Notoginseng total saponin is uniformly mixed, and obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 500-1000r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, institute
State carboxyl chitosan saponin mixed liquor addition speed be 0.01-0.1g/s to get.
10. the preparation process of light spot skin toner Essence as described in claim 6 or 7 or 8, which is characterized in that the light spot skin toner
The preparation process of Essence, comprising the following steps:
(1) it takes natural honey to be added in the water of the total dosage 45-55wt% of water to be uniformly mixed, stands 4-7h, be 3000- with revolving speed
5000r/min is centrifuged 4-10min, takes intermediate liquid, with 0.1-0.5 μm of membrane filtration, obtains hydromel；
(2) it takes carboxyl chitosan to be added in remaining water to be uniformly mixed, stands 0.5-1.5h and added with 2-5 μm of membrane filtration
Notoginseng total saponin is uniformly mixed, and obtains carboxyl chitosan saponin mixed liquor；
(3) in the case where revolving speed is 500-1000r/min stirring, carboxyl chitosan saponin mixed liquor is slowly added in hydromel, institute
The addition speed for stating carboxyl chitosan saponin mixed liquor is 0.01-0.1g/s, after carboxyl chitosan saponin mixed liquor is added
The composition with cell repair function is added, jasmine flower extract continues to be that 500-1000r/min stirs 5- with revolving speed
15min to get.
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| CN117224450A (en) * | 2023-11-10 | 2023-12-15 | 广州市玑蜜生物科技有限公司 | Fennel face essence with good moisture retention and preparation method thereof |
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