CN109433094B - Liquid dispensing device - Google Patents

Liquid dispensing device Download PDF

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Publication number
CN109433094B
CN109433094B CN201811321064.6A CN201811321064A CN109433094B CN 109433094 B CN109433094 B CN 109433094B CN 201811321064 A CN201811321064 A CN 201811321064A CN 109433094 B CN109433094 B CN 109433094B
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China
Prior art keywords
liquid
gun
raw material
plate
gun head
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CN201811321064.6A
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Chinese (zh)
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CN109433094A (en
Inventor
张晗
康建龙
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Shenzhen University
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Shenzhen University
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Priority to CN201811321064.6A priority Critical patent/CN109433094B/en
Publication of CN109433094A publication Critical patent/CN109433094A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80Forming a predetermined ratio of the substances to be mixed
    • B01F35/83Forming a predetermined ratio of the substances to be mixed by controlling the ratio of two or more flows, e.g. using flow sensing or flow controlling devices
    • B01F35/832Flow control by weighing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Coating Apparatus (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Abstract

The invention provides a liquid preparation device which comprises a raw material box, a liquid preparation plate and a liquid preparation mechanical arm, wherein the liquid preparation plate is connected to a first guide rail in a sliding manner, the liquid preparation mechanical arm and the raw material box are connected to a second guide rail in a sliding manner, the liquid preparation mechanical arm is provided with a liquid preparation gun, the liquid preparation plate is provided with a liquid preparation groove, and the liquid preparation gun is used for moving in a three-dimensional space and sucking raw material liquid from the raw material box to drop into the liquid preparation groove. Through the arrangement, the operation of sucking liquid drop by the mechanical structure is realized, manual operation is not needed, the labor intensity is lightened, and compared with manual operation, the mechanical structure has better precision and good repeatability.

Description

Liquid dispensing device
Technical Field
The invention belongs to the technical field of biomedicine, and particularly relates to a liquid preparation device.
Background
Cancer tumor treatment is a worldwide difficult problem which is not completely solved at present, researchers find that a two-dimensional material (such as a black phosphorus nano sheet) has good drug loading characteristic and permeability characteristic, and can accurately convey drugs into tumor cells, and then laser or near infrared light irradiation is applied to the two-dimensional material, so that the two-dimensional material is heated to release the drugs, the drugs act on the tumor cells, and the purpose of treating tumor diseases is achieved. In the research process, a large number of materials with different components, concentrations and the like are required to be sampled and proportioned, and interact with different illumination conditions, so that by observing the effect result, it is particularly important to provide solid test data support for the cancer treatment scheme. The existing test method adopts manual operation, needs to consume a great deal of time and effort to carry out repeated operation, and is difficult to ensure that the test process is completely consistent each time, so that the reliability of the obtained test result is reduced.
Disclosure of Invention
The invention aims to provide a liquid preparation device which does not need manual operation and has higher accuracy in multiple operations.
In order to achieve the purpose of the invention, the invention provides the following technical scheme:
in a first aspect, an embodiment of the present invention provides a liquid dispensing device, including a raw material box, a liquid dispensing plate and a liquid dispensing mechanical arm, where the liquid dispensing plate is slidably connected to a first guide rail, the liquid dispensing mechanical arm and the raw material box are slidably connected to a second guide rail, the liquid dispensing mechanical arm is provided with a liquid dispensing gun, the liquid dispensing plate is provided with a liquid dispensing groove, and the liquid dispensing gun is used to move in a three-dimensional space, and draw raw material liquid from the raw material box and drop the raw material liquid into the liquid dispensing groove.
The liquid preparation device comprises a liquid preparation plate, a liquid preparation box, a liquid preparation gun and a liquid preparation tank, wherein a plurality of grid-shaped guide rails are arranged on the liquid preparation plate, the liquid preparation box is arranged on each grid-shaped guide rail, a plurality of liquid preparation tanks are arranged on the liquid preparation box, a plurality of raw material tanks are arranged on the raw material boxes, raw material liquid stored in the raw material tanks is different, and the liquid preparation gun absorbs the raw material liquid from the raw material tanks according to a preset program and drops the raw material liquid into the liquid preparation tank.
The liquid preparation device further comprises a gun head replacing assembly, the gun head replacing assembly is arranged on the second guide rail, the liquid adding gun comprises gun heads, when liquid suction is carried out in different raw material tanks, the liquid adding gun can replace the gun heads through the gun head replacing assembly and then drip the gun heads, so that different raw material liquids are prevented from being mixed and polluted.
The gun head replacing assembly comprises a mounting groove and a dismounting groove, wherein the mounting groove is adjacent to the dismounting groove, a gun head and a gun head lifting part are arranged in the mounting groove, a gun head dismounting part is arranged in the dismounting groove and used for lifting and jacking the gun head into the liquid adding gun, and the gun head dismounting part is used for pulling the gun head down from the liquid adding gun and storing the gun head in the dismounting groove.
The liquid preparation mechanical arm further comprises a sliding plate, a sliding table, a connecting plate, a rotating wheel and a hanging plate, wherein the sliding plate is slidably connected to the second guide rail, a first sliding rail is arranged on the sliding plate and perpendicular to the extending direction of the second guide rail, the sliding table is slidably connected to the first sliding rail, the connecting plate is connected with the sliding table, the rotating wheel is rotationally connected to the periphery of the connecting plate, the hanging plate is fixedly connected to the rotating wheel, the hanging plate extends along the horizontal direction, one end of the hanging plate is provided with a liquid adding gun, and the extending direction of the liquid adding gun is vertical and downward.
The gun head replacing device comprises a gun head replacing assembly, a gun head replacing assembly and a gun head replacing assembly, wherein a supporting rod is further arranged on the suspension board, a locating hole is formed in the gun head replacing assembly, and the supporting rod is used for extending into the locating hole, so that the position of the liquid adding gun, which is moved, is limited when the gun head of the liquid adding gun is replaced.
The sliding table comprises a base and a plurality of vertical rods, wherein the base is arranged on the first sliding rail of the sliding plate, the vertical rods are vertically arranged on the base, the vertical rods are arranged at intervals, the connecting plate is a cylindrical plate, the vertical rods are arranged in the axial direction of the connecting plate in a penetrating mode, and the rotating wheel is sleeved on the peripheral wall surface of the connecting plate.
The liquid adding device comprises a hanging plate, wherein a reinforcing strip is further arranged on the hanging plate, one end of the reinforcing strip is connected to the hanging plate, and the other end of the reinforcing strip supports the liquid adding gun.
The liquid preparation device further comprises a weighing assembly, wherein the weighing assembly is used for weighing the raw material liquid; the weighing assembly comprises a container, a floating piece, a light source and a grating sensor, wherein liquid is contained in the container, an object to be measured is placed on the floating piece, the floating piece is immersed in the liquid and is in a floating shape, the light source is arranged on the floating piece and emits light, the grating sensor is arranged on the container and is used for receiving the light, and the grating sensor is used for transmitting an electric signal of information of the light.
The liquid preparation device further comprises a control component, wherein the control component is used for receiving an electric signal of the light ray information transmitted by the grating sensor and calculating the weight information of the raw material liquid so as to control the movement of the liquid preparation mechanical arm.
Through setting up liquid dispensing board and liquid dispensing arm, liquid dispensing arm can slide on the second guide rail, and liquid dispensing rifle can be at three-dimensional space removal, and liquid dispensing board can slide on first guide rail, can mutually support between liquid dispensing arm and the liquid dispensing board for liquid dispensing rifle can follow the raw materials liquid of absorbing in the raw materials box and drip into liquid dispensing inslot, realizes that mechanical structure carries out the operation of liquid droplet liquid of inhaling, does not need the manual work to go on, has alleviateed intensity of labour, and mechanical structure compares in manual operation, can have better precision, and the repeatability is good.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of an arrangement of a liquid dispensing device according to an embodiment;
FIG. 2a is a schematic plan view of a liquid distribution plate according to an embodiment;
FIG. 2b is a schematic perspective view of a liquid distribution plate according to an embodiment;
FIG. 3a is a schematic plan view of a liquid dispensing mechanical arm according to an embodiment;
FIG. 3b is a schematic perspective view of a liquid dispensing robot according to an embodiment;
FIG. 3c is a schematic perspective view of the dispensing robot of FIG. 3b from another perspective;
FIG. 3d is a schematic perspective view of the other view of the dispensing robot of FIG. 3 b;
FIG. 4 is a schematic diagram of the weighing assembly of one embodiment.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1, 2a and 3b, an embodiment of the present invention provides a liquid dispensing device, which includes a raw material box 34, a liquid dispensing plate 22 and a liquid dispensing mechanical arm 32, wherein the liquid dispensing plate 22 is slidably connected to a first guide rail 21, and the liquid dispensing mechanical arm 32 and the raw material box 34 are slidably connected to a second guide rail 31. The liquid dispensing mechanical arm 32 is provided with a liquid dispensing gun 326, the liquid dispensing plate 22 is provided with a liquid dispensing groove 231, and the liquid dispensing gun 326 is used for moving in a three-dimensional space and sucking raw material liquid from the raw material box 34 to drop into the liquid dispensing groove 231.
Through setting up liquid dispensing plate 22 and liquid dispensing arm 32, liquid dispensing arm 32 can slide on second guide rail 31, and liquid dispensing rifle 326 can be at three-dimensional space removal, and liquid dispensing plate 22 can slide on first guide rail 21, can mutually support between liquid dispensing arm 32 and the liquid dispensing plate 22 for liquid dispensing rifle 326 can draw the raw materials liquid from raw materials box 34 in instil into liquid dispensing groove 231, realizes that mechanical structure carries out the operation of liquid droplet liquid that absorbs, does not need the manual work to go on, has alleviateed intensity of labour, and mechanical structure compares manual operation, can have better precision, and the repeatability is good.
Referring to fig. 1, in an embodiment, in an application of a typical liquid dispensing device, the liquid dispensing device of this embodiment may be used to provide a raw material liquid to a laboratory table 1. The test stand 1 may be provided with various functional devices, and the prepared raw material liquid may be sucked from the liquid preparation tank 231 on the liquid preparation plate 22 and used in various experimental steps.
In an embodiment, referring to fig. 2a, fig. 2b, fig. 3a, and fig. 3b, the liquid distribution plate 22 is provided with a plurality of grid-shaped rails 221, each grid-shaped rail 221 is provided with a liquid distribution box 23, the liquid distribution box 23 is provided with a plurality of liquid distribution boxes 231, the raw material box 34 is provided with a plurality of raw material tanks 341, each raw material tank 341 stores different raw material liquid, and the liquid feeding gun 326 sucks the raw material liquid from the raw material tank 341 according to a preset program and drops the raw material liquid into the liquid distribution boxes 231.
In this embodiment, by setting the plurality of grid-shaped rails 221 on the liquid dispensing plate 22, and setting the liquid dispensing boxes 23 on each grid-shaped rail 221, and setting the plurality of liquid dispensing tanks 231 on each liquid dispensing box 23, the liquid dispensing gun 326 can continuously drip liquid into the plurality of liquid dispensing tanks 231 according to a preset program, and setting the plurality of raw material tanks 341 with different raw material liquids, so that the raw material liquids dripped into the liquid dispensing tanks 231 can be different, thereby preparing various required liquids and supplying various experiments.
In this embodiment, the liquid dispensing boxes 23 may slide on the grid-shaped guide rails 221, and the extending directions of the plurality of grid-shaped guide rails 221 may be the same, so that the relative positions between the liquid dispensing boxes 23 on each grid-shaped guide rail 221 and the liquid dispensing boxes 23 on the adjacent grid-shaped guide rails 221 may be staggered, and the specific positions of the staggered arrangement may be controlled by a preset program according to the experiment requirement. On this basis, the purpose of batch transfer can be realized by sucking the raw material liquid in the liquid preparation tank 231 in the liquid preparation boxes 23 by functional devices on the experiment table, such as a matrix type liquid sucking gun (i.e. a liquid sucking gun with a plurality of suction nozzles and a plurality of suction nozzles arranged in a matrix type). Therefore, by providing a plurality of liquid dispensing boxes 23 and sliding the liquid dispensing boxes relative to the grid-shaped guide rail 221, liquid dispensing efficiency can be improved and experimental period can be shortened.
In this embodiment, the liquid dispensing tanks 231 on the liquid dispensing box 23 have the same size, and the liquid dispensing tanks 231 are arranged at intervals along the extending direction of the grid-type guide rail 221, preferably in an array arrangement. The grid-shaped guide rail 221 may be a structure protruding above the liquid dispensing plate 22, such as a screw, a rack, etc.; or may be a structure recessed inward from the surface of the liquid distribution plate 22. The liquid dispensing box 23 may be integrally connected to the grid-shaped rail 221, or a connection portion 232 may be provided at the bottom of the liquid dispensing box 23 to be connected to the grid-shaped rail 221.
In one embodiment, since the raw material liquid has a plurality of components, such as common and expensive components, and the expensive liquid is very expensive, such as 10000 RMB/. Mu.L, and needs a small amount of use and special condition for preservation, a heat-insulating structure can be further arranged on the liquid preparation plate 22 to ensure the effectiveness of the expensive liquid. During liquid preparation, the refined noble liquid is contained on a special refined noble raw material box, and the structure of the refined noble raw material box is similar to that of the liquid preparation box 23, except that the size of the refined noble raw material box is smaller, and a heat preservation structure can be arranged.
In an embodiment, please refer to fig. 3a to 3d, the dispensing device further includes a gun head replacing assembly 33, the gun head replacing assembly 33 is disposed on the second guide rail 31, the filling gun 326 includes a gun head (not shown in the drawing), and when different raw materials in the raw materials tank 341 are absorbed, the filling gun 326 replaces the gun head by the gun head replacing assembly 34 and then performs dripping, so as to avoid pollution caused by mixing different raw materials.
In this embodiment, referring to fig. 1 and 3d, the gun head assembly 33 may be fixedly connected to the dispensing mechanical arm 32, and the gun head assembly 33 is disposed on a side of the dispensing mechanical arm 32 away from the raw material box 34. The relative position between the gun head assembly 33 and the liquid preparation mechanical arm 32 is fixed, namely, the gun head assembly 33 moves on the second guide rail 31 along with the liquid preparation mechanical arm 32, so that the gun head can be replaced at any position on the second guide rail 31, the gun head can be replaced without moving the liquid preparation mechanical arm 32 to a fixed position, the gun head replacement efficiency is improved, and the overall liquid preparation efficiency is also improved.
In an embodiment, please refer to fig. 3b and 3c, the gun head assembly 33 includes a mounting groove 332 and a dismounting groove 333, the mounting groove 332 and the dismounting groove 333 are disposed adjacent, a gun head and a gun head lifting member are disposed in the mounting groove 332, a gun head dismounting member is disposed in the dismounting groove 333, the gun head lifting member is used for lifting and jacking the gun head into the filling gun 326, and the gun head dismounting member is used for pulling the gun head from the filling gun 326 and accommodating the gun head in the dismounting groove 333.
In this embodiment, the installation groove 332 and the disassembly groove 333 are provided, so that not only the gun head can be accommodated, but also a gun head lifting member or a gun head disassembly member is provided. When the filling gun 326 moves to the position right above the mounting groove 332, the gun head lifting piece can be lifted, and the gun head is mounted on the filling gun 326, so that the filling gun 326 can perform liquid sucking operation; when the liquid sucking and dropping is completed or different raw material liquids need to be sucked, the gun head needs to be replaced, at the moment, the liquid adding gun 326 is moved to the position right above the disassembling groove 332, and the gun head disassembling piece clamps the gun head and pulls the gun head towards the direction of the disassembling groove 332 until the gun head is pulled down. After the gun head is detached from the liquid adding gun 326, the gun head is mounted right above the mounting groove 332 by moving the liquid adding gun 326, and the liquid sucking operation is continued.
In this embodiment, the gun head lifting member and the gun head dismounting member may have existing structures, such as a lifting rod with a clamping portion, which can be lifted, and one end of the lifting rod is fixed on the bottom wall of the mounting groove 332 or the dismounting groove 333, and the other end has a holding portion, which can clamp the gun head and perform lifting movement. It will be appreciated that the end of the filling gun 326 is provided with a connection port for connection with the gun head. The connection port may be similar to the port of a syringe and the gun head may be similar to the structure of the needle of a syringe.
In an embodiment, please refer to fig. 3a to 3d, the liquid dispensing mechanical arm 32 further includes a sliding plate 321, a sliding table 322, a connecting plate 323, a rotating wheel 324 and a suspension plate 325, the sliding plate 321 is slidably connected to the second guide rail 31, a first sliding rail 3211 is disposed on the sliding plate 321, the first sliding rail 3211 is perpendicular to the extending direction of the second guide rail 31, the sliding table 322 is slidably connected to the first sliding rail 3211, the connecting plate 323 is connected to the sliding table 322, the rotating wheel 324 is rotatably connected to the periphery of the connecting plate 323, the suspension plate 325 is fixedly connected to the rotating wheel 324, the suspension plate 325 extends along the horizontal direction, and one end portion is provided with the liquid adding gun 326, and the extending direction of the liquid adding gun 326 is vertically downward.
In this embodiment, by arranging the sliding plate 321 and the first sliding rail 3211, the sliding table 322 is slidably connected to the first sliding rail 3211, the rotating wheel 324 is rotatably connected to the connecting plate 323, the cantilever plate 325 is connected to the rotating wheel 324, so that the liquid adding gun 326 arranged on the cantilever plate 325 can move along the first guiding rail 31 and the first sliding rail 3211 and also can rotate along the rotating wheel 324, and thus the liquid adding gun 326 can move in a three-dimensional space, and the liquid adding gun 326 can perform liquid sucking operation on any position.
Referring to fig. 3c, the suspension board 325 is further provided with a supporting rod 327, the gun head assembly 33 is provided with a positioning hole 331, and the supporting rod 327 is configured to extend into the positioning hole 327, so that the position of the liquid adding gun 326 is limited when the gun head is replaced.
In this embodiment, the gun head assembly 33 has an upward pushing action on the liquid filling gun 326 when the gun head is installed, so that the whole liquid dispensing mechanical arm 32 bears an upward pressure; when the gun head is detached, the gun head replacing assembly 33 will pull the liquid adding gun 326 downward, so that the whole liquid dispensing mechanical arm 32 is under downward pulling force. In order to make the dispensing mechanical arm 32 stable in structure, the dispensing mechanical arm 32 will not be unbalanced due to the pressure or the tension, so the support rod 327 is matched with the positioning hole 331, so that after the support rod 327 is fixed with the positioning hole 331, the gun exchange head assembly 33 shares a part of the pressure or the tension received by the dispensing mechanical arm 32. In addition, the positioning hole 331 is matched with the supporting rod 327, so that the alignment of the liquid adding gun 326 and the mounting groove 332 or the dismounting groove 333 can be realized, and the positioning effect can be realized.
Specifically, the gun head assembly 33 may be composed of a plurality of plate-like structures that are respectively enclosed to form the mounting groove 332 and the dismounting groove 333. In one embodiment, the mounting groove 332 is disposed on a side of the dismounting groove 333 facing away from the liquid dispensing mechanical arm 32, and the positioning hole 331 is disposed on a plate of the plate structure surrounding the mounting groove 332 on a side far from the dismounting groove 333.
In an embodiment, please refer to fig. 3c, the sliding table 322 includes a base and a plurality of vertical rods 3221, the base is disposed on the first sliding rail 3211 of the sliding plate 321, the plurality of vertical rods 3221 are vertically disposed on the base, and the plurality of vertical rods 3221 are disposed at intervals. The connecting plate 323 is a cylindrical plate, the plurality of vertical rods 3221 are arranged on the axial direction of the connecting plate 323 in a penetrating manner, and the rotating wheel 324 is sleeved on the peripheral wall surface of the connecting plate 323.
In this embodiment, by providing the plurality of vertical rods 3221, the plurality of vertical rods 3221 can achieve better support with lighter weight than if one rod-like structure were provided. The supporting structures formed by the plurality of vertical rods 3221 are respectively arranged around the axis of the center of the circle of the connecting plate 323, and are arranged in a central symmetry manner relative to the center of the circle. The number of the plurality of vertical rods 3221 is preferably 4, and the vertical rods 3221 may be elongated rods with circular cross sections. In one embodiment, the connecting plate 323 can slide relative to the plurality of vertical rods 3221, so that the liquid adding gun 326 can also realize up-and-down lifting motion, and the liquid sucking operation is more convenient. In addition, the liquid adding gun 326 can be lifted when the gun head is replaced, and the gun head lifting piece and the gun head dismounting piece can be moved simultaneously or not, so that the gun head can be replaced conveniently.
In one embodiment, referring to fig. 3c, the cantilever plate 325 is further provided with a reinforcing bar 3261, one end of the reinforcing bar 3261 is connected to the cantilever plate 325, and the other end supports the filling gun 326.
Referring to fig. 3c and 3d, in this embodiment, a spacer 3262 may be further provided, the spacer 3262 is connected between the cantilever plate 325 and the filling gun 326, one end of the reinforcing bar 3261 is connected to the spacer 3262, and the other end is connected to the filling gun 326. Further, a second sliding rail 3251 may be further disposed on a surface of the cantilever plate 325 facing the liquid filling gun 326, where an extending direction of the second sliding rail 3251 is the same as that of the cantilever plate 325, and the cushion blocks 3262 may be slidably connected to the second sliding rail 3251 along a radial direction of the connecting plate 323, so that the liquid filling gun 326 may move in the radial direction of the connecting plate 325, and further facilitate the liquid sucking and dropping operations from the liquid filling gun 326 to various positions. Of course, movement of the filler gun 326 also facilitates alignment of the filler gun 326 over the mounting slots 332 or the dismounting slots 333 during gun head replacement.
In one embodiment, referring to fig. 4, the liquid dispensing device further includes a weighing assembly 40, where the weighing assembly 40 is used for weighing the raw material liquid; the weighing assembly 40 comprises a container 41, a floating member 42, a light source 43 and a grating sensor 44, wherein a liquid 46 is contained in the container 41, an object 45 to be measured is placed on the floating member 41, the floating member 41 is immersed in the liquid 46 and is in a floating shape, the light source 43 is arranged on the floating member 42 and emits light, the grating sensor 44 is arranged on the container 41 and is used for receiving the light, and the grating sensor 44 is used for transmitting an electric signal of information of the light.
In this embodiment, by arranging the floating member 42 to float on the liquid 46 in the container 41, the weight of the object 45 to be measured is different, and the depth of the floating member 42 immersed in the liquid 46 is different, the position of the light emitted by the light source 43 and received by the grating sensor 44 is different, and the electric signal of the information of the light collected by the grating sensor 44 can be used to calculate the weight of the object 45 to be measured.
In this embodiment, the object 45 may be a glass bottle, and the glass bottle may contain a raw material liquid. In the initial state, i.e. when the raw material liquid is not contained, the weight of the empty glass bottle can be obtained, at this time, the weight corresponding to the electric signal of the light collected by the grating sensor 44 is 0, after the raw material liquid is contained in the glass bottle, the light collected by the grating sensor 44 changes due to the floating of the floating member 42, and at this time, the weight of the raw material liquid can be obtained according to the corresponding relation between the electric signal of the light and the weight of the preset standard.
In this embodiment, the container 41 includes a bottom wall and two opposite side walls, and the grating sensor 44 may be disposed on one side wall. The liquid 46 in the container 41 may be water or other liquid. The float 42 is immersed in the liquid 46 and does not contact the bottom wall or side walls of the container 41. The float 42 includes a main body 421, a weight 424, and a bracket, the main body 421 having a support surface for supporting the object 45 to be measured, and extension legs for immersing in the liquid 46. The weight 424 is disposed on the same side of the body 421 as the extension leg, and the weight 424 is also at least partially immersed in the liquid 46. A bracket is provided on the support surface and opposite the extension leg, the bracket being provided for the provision of a light source 43. Specifically, the body 421 may have a shape in which two legs (of course, two plates may be provided) extend from opposite side edges of a single plate, and the two legs are perpendicular to the plate. The weight portion 424 is disposed between the two legs such that the overall shape of the body 421 and the weight portion 424 is inverted "mountain" shaped. The support may be formed by a cross member 427 of the support bar 426, the support bar 426 may be provided in two and spaced apart relationship, one end of the support bar 426 is connected to the support surface of the main body 421, the opposite end extends in a direction away from the main body 421, preferably the support bar 426 is perpendicular to the support surface, and the cross member 427 is provided on the two support bars 426. The light source 43 is suspended from the beam 427 by suspension 428. In order to facilitate the design of the light path of the light source 43, a reflecting surface 425 may be provided on the supporting surface of the main body 421, and the light source 43 emits light toward the reflecting surface 425, and the line with an arrow on the straight line shown in fig. 4 is an indication of light, and the light is reflected to the sidewall of the container 41 by the reflecting surface 425 and collected by the grating sensor 44 on the sidewall of the container 41.
In this embodiment, since the weight of the raw material liquid to be measured is various, the weighing module of this embodiment needs to accommodate weighing of various weights, such as a large span of 0.1mg, 1g, 1kg, etc. In order to achieve a large scale of weighing, in this embodiment, a plurality of weight portions 424 may be provided, as shown in 3 in fig. 4, with reference numerals of a first disposition portion 422, a second weight portion 423, and a third weight portion 424, respectively, and the volumes of the plurality of weight portions 424 are different, so that the buoyancy of the liquid 46 after immersing in the liquid 46 is different. Preferably, the volumes of the plurality of weight portions 424 gradually decrease from the surface of the body portion 421 toward the bottom wall of the container 41, and a step is formed between two adjacent weight portions. Taking fig. 4 as an example, when the weight of the micro-amount of the material liquid is weighed, a part of the third weight portion 424 having the smallest volume is immersed in the liquid 46, when the weight of the material liquid increases, all of the third weight portion 424 enters the immersed liquid 46, and when the weight of the material liquid continues to increase, the second weight portion 424 also starts to be immersed in the liquid 46, and so on until all of the first weight portion 422 is immersed in the liquid 46, and the maximum range of the weighing assembly is reached.
It can be seen that the plurality of weight portions 424 are provided, each weight portion 424 has different sensitivity and accuracy, for example, as shown in fig. 4, the accuracy of the weight that the third weight portion 424 can measure is 0.1mg, the accuracy of the weight that the second weight portion 423 can measure is 1mg, and the accuracy of the weight that the first weight portion 422 can measure is 1g. So that the sensitivity of the measurement is highest when only the third weight 424 is immersed in the liquid 46, a minute amount of the raw material liquid can be measured. The sensitivity of the measurement of the second weight portion 423 immersed in the liquid 46 and the first weight portion 422 immersed in the liquid 46 gradually decreases. The weighing mode can be suitable for particularly delicate and precious raw material liquid, and can accurately measure when the weighing mode is used in a trace amount in order to reduce waste and save cost; the method can also be used for common raw material liquid, has low cost, is not particularly sensitive to weight, and can be used for rough measurement.
In an embodiment, referring to fig. 4 in combination with fig. 1, the liquid dispensing device further includes a control component, where the control component is configured to receive an electrical signal of the light information transmitted by the grating sensor 44, and calculate the weight information of the raw material liquid, so as to control the movement of the liquid dispensing mechanical arm 32.
In this embodiment, the control component may be provided with big data or artificial intelligence software, and the big data or artificial intelligence software may calculate to obtain the weight information of the raw material liquid, and may also control the movement of the liquid dispensing mechanical arm 32, so as to implement automatic liquid dispensing operation.
The above disclosure is only a preferred embodiment of the present invention, and it should be understood that the scope of the invention is not limited thereto, and those skilled in the art will appreciate that all or part of the procedures described above can be performed according to the equivalent changes of the claims, and still fall within the scope of the present invention.

Claims (7)

1. The liquid preparation device is characterized by comprising a raw material box, a liquid preparation plate and a liquid preparation mechanical arm, wherein the liquid preparation plate is connected to a first guide rail in a sliding manner, the liquid preparation mechanical arm and the raw material box are connected to a second guide rail in a sliding manner, the liquid preparation mechanical arm is provided with a liquid preparation gun, the liquid preparation plate is provided with a liquid preparation tank, and the liquid preparation gun is used for moving in a three-dimensional space and sucking raw material liquid from the raw material box to drop into the liquid preparation tank;
the liquid preparation device further comprises a weighing assembly, wherein the weighing assembly is used for weighing the weight of the raw material liquid; the weighing assembly comprises a container, a floating piece, a light source and a grating sensor, wherein liquid is contained in the container, an object to be measured is placed on the floating piece, the floating piece is immersed in the liquid and is in a floating shape, the light source is arranged on the floating piece and emits light, the grating sensor is arranged on the container and is used for receiving the light, and the grating sensor is used for transmitting an electric signal of information of the light; the container comprises a bottom wall and two opposite side walls, and the grating sensor is arranged on one side wall;
the liquid preparation mechanical arm further comprises a sliding plate, a sliding table, a connecting plate, a rotating wheel and a hanging plate, wherein the sliding plate is connected to the second guide rail in a sliding manner, a first sliding rail is arranged on the sliding plate, the first sliding rail is perpendicular to the extending direction of the second guide rail, the sliding table is connected to the first sliding rail in a sliding manner, the connecting plate is connected with the sliding table, the rotating wheel is connected to the periphery of the connecting plate in a rotating manner, the hanging plate is fixedly connected to the rotating wheel, the hanging plate extends along the horizontal direction, one end part of the hanging plate is provided with a liquid adding gun, and the extending direction of the liquid adding gun is vertical downward;
the sliding table comprises a base and a plurality of vertical rods, wherein the base is arranged on the first sliding rail of the sliding plate, the vertical rods are vertically arranged on the base, the vertical rods are arranged at intervals, the connecting plate is a cylindrical plate, the vertical rods are arranged in the axial direction of the connecting plate in a penetrating mode, and the rotating wheel is sleeved on the peripheral wall surface of the connecting plate.
2. The liquid dispensing device according to claim 1, wherein a plurality of grid-shaped guide rails are arranged on the liquid dispensing plate, a liquid dispensing box is arranged on each grid-shaped guide rail, a plurality of liquid dispensing tanks are arranged on the liquid dispensing box, a plurality of raw material tanks are arranged on the raw material box, raw material liquids stored in each raw material tank are different, and the liquid dispensing gun sucks the raw material liquids from the raw material tanks according to a preset program and drops the raw material liquids into the liquid dispensing tanks.
3. The liquid dispensing device of claim 2, further comprising a gun head changing assembly disposed on the second guide rail, wherein the liquid adding gun comprises a gun head, and when liquid is absorbed in different raw material tanks, the liquid adding gun is dripped through the gun head changing assembly to avoid mixing different raw material liquids.
4. A liquid dispensing device according to claim 3, wherein the gun head assembly comprises a mounting groove and a dismounting groove, the mounting groove and the dismounting groove are adjacently arranged, a gun head and a gun head lifting member are arranged in the mounting groove, a gun head dismounting member is arranged in the dismounting groove and is used for lifting and jacking the gun head into the liquid adding gun, and the gun head dismounting member is used for pulling the gun head from the liquid adding gun and is contained in the dismounting groove.
5. A dispensing device as claimed in claim 3 wherein the hanger plate is further provided with a spacer, the gun head assembly is provided with a locating hole, and the spacer is adapted to extend into the locating hole so that the gun is restrained from moving when the gun head is replaced.
6. The dispensing device of claim 1 wherein said hanger plate is further provided with a reinforcing bar, one end of said reinforcing bar being attached to said hanger plate and the other end of said reinforcing bar supporting said liquid dispensing gun.
7. The liquid dispensing device of claim 1, further comprising a control assembly for receiving an electrical signal from the information about the light transmitted by the grating sensor and calculating weight information of the feed liquid to control movement of the liquid dispensing robot.
CN201811321064.6A 2018-11-07 2018-11-07 Liquid dispensing device Active CN109433094B (en)

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CN111773984B (en) * 2020-07-27 2022-10-21 河南科技大学第一附属医院 A supplementary dispensing device of western medicine for clinical pharmacy

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010058184A (en) * 2008-09-01 2010-03-18 Gifu Univ Liquid conveyance apparatus
CN205437644U (en) * 2016-04-07 2016-08-10 佛山市百冠科技有限公司 Welder adjuster that can three -dimensionally adjust
CN105853223A (en) * 2016-04-28 2016-08-17 吉林大学 Automatic medicine dispensing device based on macro/micro driving and precise liquid medicine control
JP2017050460A (en) * 2015-09-03 2017-03-09 株式会社ディスコ Solution manufacturing device
CN107855072A (en) * 2017-11-30 2018-03-30 韩秋霞 A kind of molten robot that makes up a prescription of rotating disc type cillin bottle
CN107916222A (en) * 2017-12-05 2018-04-17 上海百力格生物技术有限公司 The accurate packing of a kind of DNA primer or probe and mixing arrangement and its application method
CN107917747A (en) * 2017-11-15 2018-04-17 中国计量大学 A kind of hand-held capacity calibration device of pipettor and its calibration method
CN209501600U (en) * 2018-11-07 2019-10-18 深圳大学 Liquid dispensing device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010058184A (en) * 2008-09-01 2010-03-18 Gifu Univ Liquid conveyance apparatus
JP2017050460A (en) * 2015-09-03 2017-03-09 株式会社ディスコ Solution manufacturing device
CN205437644U (en) * 2016-04-07 2016-08-10 佛山市百冠科技有限公司 Welder adjuster that can three -dimensionally adjust
CN105853223A (en) * 2016-04-28 2016-08-17 吉林大学 Automatic medicine dispensing device based on macro/micro driving and precise liquid medicine control
CN107917747A (en) * 2017-11-15 2018-04-17 中国计量大学 A kind of hand-held capacity calibration device of pipettor and its calibration method
CN107855072A (en) * 2017-11-30 2018-03-30 韩秋霞 A kind of molten robot that makes up a prescription of rotating disc type cillin bottle
CN107916222A (en) * 2017-12-05 2018-04-17 上海百力格生物技术有限公司 The accurate packing of a kind of DNA primer or probe and mixing arrangement and its application method
CN209501600U (en) * 2018-11-07 2019-10-18 深圳大学 Liquid dispensing device

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