CN109432341A - The application of Chinese medicine composition and Chinese materia medica preparation and they - Google Patents

The application of Chinese medicine composition and Chinese materia medica preparation and they Download PDF

Info

Publication number
CN109432341A
CN109432341A CN201811547266.2A CN201811547266A CN109432341A CN 109432341 A CN109432341 A CN 109432341A CN 201811547266 A CN201811547266 A CN 201811547266A CN 109432341 A CN109432341 A CN 109432341A
Authority
CN
China
Prior art keywords
weight
content
parts
medicine composition
chinese medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811547266.2A
Other languages
Chinese (zh)
Inventor
徐修信
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201811547266.2A priority Critical patent/CN109432341A/en
Publication of CN109432341A publication Critical patent/CN109432341A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/10—Peat; Amber; Turf; Humus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/52—Juglandaceae (Walnut family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/69—Polygalaceae (Milkwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8988—Gastrodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The present invention relates to food and medicine consangunity field of Chinese medicinal composition, disclose the application of a kind of Chinese medicine composition and Chinese materia medica preparation and they, the Chinese medicine composition contains following raw material: hollyhock essence, ginkgo leaf, ginseng, Radix Astragali, semen coicis, pilose antler, triangle vine, cynomorium songaricum, very little rue, complanate astragalus seed, Cortex Cinnamomi, asarum, process rhizoma typhonii, radix glycyrrhizae preparata, wherein, the total weight of the Chinese medicine composition relative to 100 parts by weight, the content of the hollyhock essence is 5-20 parts by weight, ginkgo leaf, ginseng, Radix Astragali, semen coicis, triangle vine, cynomorium songaricum, the content of very little rue is respectively 8-12 parts by weight, the content of pilose antler is 3-8 parts by weight, the content of complanate astragalus seed is 6-10 parts by weight, the content of Cortex Cinnamomi is 0.5-3 parts by weight, the content of asarum is 0.3-0.8 parts by weight, the content for processing rhizoma typhonii is 0.5-3 weight Part, the content of radix glycyrrhizae preparata be 3-8 parts by weight.Chinese materia medica preparation provided by the invention has effects that adjust blood stasis and acidic constitution.

Description

The application of Chinese medicine composition and Chinese materia medica preparation and they
Technical field
The present invention relates to food and medicine consangunity field of Chinese medicinal composition, and in particular to a kind of Chinese medicine composition and its is used in preparation Improving the drug of sleep quality and substance in vivo dysbolism and/or application in food and one kind with the Chinese medicine composition is The Chinese materia medica preparation of active constituent and its application in drug of the preparation for improving sleep quality and substance in vivo dysbolism.
Background technique
Obstacle occurs for lipid metaboli in human body, and fatty quantity has exceeded normal range (NR), can be deposited on organ, generates to organ Toxicity forms injury, leads to serious lipid metaboli disease.Such as cardiovascular and cerebrovascular diseases, diabetes, fatty liver, these extra rouge Fat is medically known as " rouge poison " to the toxicity of human body.
Oxygen radical can be generated into intracorporal oxygen, oxygen radical is extremely active, flees hither and thither in vivo, attacks and kills Various cells, lead to the metabolism and dysfunction of cell and organ, and gene mutation can be promoted to induce cancer.Healthy People is in nature Under state, vivo oxidation and anti-oxidant movement are in dynamic equilibrium.When the accumulation of oxygen poison will lead to human body and generate photis, unreal in human body It listens, the symptoms such as olfactory hallucination, oral peculiar smell and abnormal feeling.
It is damp and hot poison contain card, be that cold-evil accumulates long, it is strongly fragrant and change heat, it is damp and hot contamination and occur syndrome.It is common in the gangrene of finger or toe.Cold-evil is long Accumulate, strongly fragrant and change heat, damp and hot contamination then suffers from the red and swollen routed purulence of toe (finger)；Pyretic damage of yin can cause fire excess from yin deficiency.The sick deficiency of vital energy positive long cannot resist Heresy, gangrene, high fever, severe pain continue with the passing of time, to may occur in which body syntexis, burnout out of strength, neurolysis, do not feel like eating, unconsciousness due to high fever Etc. critical syndrome.Clinical manifestation is suffering limb severe pain, and day at light night is heavy, local swelling, and skin is purple dark, and contamination sprawling, ulceration is rotten, meat Color is not fresh；The hot dry of body, constipation is urinated red；Tongue is red, yellow and greasy fur, wiry and frequent pulse.
Blood stasis, that is, blood operation is unsmooth, all blood for leaving passages through which vital energy circulates cannot dissipate in time with the stasis of blood it is stagnant in certain or blood flow not Freely, operation is obstructed, and is pooled within passages through which vital energy circulates or organ in the state of stagnating, is all blood stasis.Blood stasis constitution person is easy to appear silt blueness, face Color is black, pigmentation easily occur, easily long spot, tongue be dim, body is easy to happen the easy bleeding of pain, gum；It is shown as in psychological aspects It is easy agitation, is also easy to the symptoms such as amnesia occur.When various toxin, waste will cause metabolic disorder because blood stasis retains in vivo, Hinder qi and blood operate normally, destroy internal organs function and internal organs it is dirty between it is mutually coordinated.
Chinese medicine thinks to reduce the generations of toxins in human body such as internal rouge is malicious, oxygen is malicious, chill is damp and hot, keeps gas row healthy and vigorous and blood Row is unimpeded, adjusts lining qi and blood balance, and the colour of skin could be full ruddy, and people are just able to maintain energetic, and body and mind is happy, and physique is strong It is strong, it prolongs life.
There are many medicament categories of sleep quality and substance in vivo dysbolism and dosage form is various for improving currently on the market, Although certain effect can be played, there are still eating, medicine decocting time is long, not portable, unbalanced nutrition, is unfavorable for inhaling The problems such as receipts and holding time are short.
Summary of the invention
The purpose of the invention is to overcome the drug for being currently used for improving sleep quality and substance in vivo dysbolism to deposit Medicine decocting time is long, not portable, unbalanced nutrition, is unfavorable for absorbing and the defects of the holding time is short, provides one kind and have both eating It is convenient to take, portable, nutrition is balanced, conducive to absorb and the holding time it is long the advantages that Chinese medicine composition and its preparation for improving The drug of sleep quality and substance in vivo dysbolism and/or application in food and it is a kind of with the Chinese medicine composition be activity The Chinese materia medica preparation of ingredient and its application in drug of the preparation for improving sleep quality and substance in vivo dysbolism.
To achieve the goals above, one aspect of the present invention provides a kind of Chinese medicine composition, which contains following Raw material: hollyhock essence, black hyacinth bean, uncaria, Rhizoma Gastrodiae, peach kernel, safflower, fushen, Radix Polygalae, amber, rhizoma acori graminei, goldleaf, fructus alpiniae oxyphyllae, wild jujube Benevolence, fructus schisandrae, lotus nut, walnut kernel, cape jasmine, sweet wormwood, humus flava usta, Radix Glycyrrhizae, wherein the Chinese medicine relative to 100 parts by weight The total weight of composition, the content of the hollyhock essence is 3-15 parts by weight, the content of black hyacinth bean is that 3-15 parts by weight, uncaria contain Amount is 3-15 parts by weight, the content of Rhizoma Gastrodiae is 2-12 parts by weight, the content of peach kernel is 2-12 parts by weight, the content of safflower is 2-12 Parts by weight, the content of fushen are 2-12 parts by weight, the content of Radix Polygalae is 2-10 parts by weight, the content of amber be 2-10 parts by weight, The content of rhizoma acori graminei is 0.5-8 parts by weight, the content of goldleaf is 0.01-0.05 parts by weight, the content of fructus alpiniae oxyphyllae is 2-10 weight Part, the content of semen ziziphi spinosae be 2-10 parts by weight, the content of fructus schisandrae is 2-10 parts by weight, the content of lotus nut is 2-10 weight Part, the content of walnut kernel be 2-10 parts by weight, the content of cape jasmine is 0.5-7 parts by weight, the content of sweet wormwood be 0.3-6 parts by weight, The content of humus flava usta is 0.5-7 parts by weight, the content of Radix Glycyrrhizae is 0.3-6 parts by weight.
Second aspect of the present invention provides above-mentioned Chinese medicine composition in preparation for improving sleep quality and substance in vivo metabolism Application in the drug of obstacle.
Third aspect present invention provides above-mentioned Chinese medicine composition in preparation for improving sleep quality and substance in vivo metabolism Application in the food of obstacle.
Fourth aspect present invention provides a kind of Chinese materia medica preparation, which contains active constituent and auxiliary material, wherein described Active constituent is aforementioned Chinese medicine composition.
Fifth aspect present invention provides a kind of aforementioned Chinese materia medica preparation in preparation for improving sleep quality and substance in vivo generation Thank to the application in the drug of obstacle.
Chinese medicine composition and Chinese drugs agentia provided by the invention have it is convenient to take, portable, nutrition is balanced, be conducive to absorb and The advantages that holding time is long can be effectively improved sleep quality and substance in vivo dysbolism.
Other features and advantages of the present invention will the following detailed description will be given in the detailed implementation section.
Specific embodiment
The endpoint of disclosed range and any value are not limited to the accurate range or value herein, these ranges or Value should be understood as comprising the value close to these ranges or value.For numberical range, between the endpoint value of each range, respectively It can be combined with each other between the endpoint value of a range and individual point value, and individually between point value and obtain one or more New numberical range, these numberical ranges should be considered as specific open herein.
As previously mentioned, first aspect present invention provides a kind of Chinese medicine composition, which contains following raw material: another name for Sichuan Province Certain herbaceous plants with big flowers essence, black hyacinth bean, uncaria, Rhizoma Gastrodiae, peach kernel, safflower, fushen, Radix Polygalae, amber, rhizoma acori graminei, goldleaf, fructus alpiniae oxyphyllae, semen ziziphi spinosae, north five Taste, lotus nut, walnut kernel, humus flava usta, cape jasmine, sweet wormwood, Radix Glycyrrhizae, wherein the Chinese medicine composition relative to 100 parts by weight Total weight, the content of the hollyhock essence is 3-15 parts by weight, the content of black hyacinth bean is 3-15 parts by weight, the content of uncaria is 3-15 Parts by weight, the content of Rhizoma Gastrodiae are 2-12 parts by weight, the content of peach kernel is 2-12 parts by weight, the content of safflower be 2-12 parts by weight, The content of fushen is 2-12 parts by weight, the content of Radix Polygalae is 2-10 parts by weight, the content of amber is 2-10 parts by weight, rhizoma acori graminei Content is 0.5-8 parts by weight, the content of goldleaf is 0.01-0.05 parts by weight, the content of fructus alpiniae oxyphyllae is 2-10 parts by weight, semen ziziphi spinosae Content be 2-10 parts by weight, the content of fructus schisandrae is 2-10 parts by weight, the content of lotus nut is 2-10 parts by weight, walnut kernel Content is 2-10 parts by weight, the content of cape jasmine is 0.5-7 parts by weight, the content of sweet wormwood is 0.3-6 parts by weight, the content of humus flava usta It is 0.3-6 parts by weight for 0.5-7 parts by weight, the content of Radix Glycyrrhizae.
Under preferable case, the content of the total weight of the Chinese medicine composition relative to 100 parts by weight, the hollyhock essence is 5-12 parts by weight, the content of black hyacinth bean are 5-12 parts by weight, the content of uncaria is 5-12 parts by weight, the content of Rhizoma Gastrodiae is 3-10 weight Measure part, the content of peach kernel is 3-10 parts by weight, the content of safflower is 3-10 parts by weight, the content of fushen is 3-10 parts by weight, remote The content of will is 3-8 parts by weight, the content of amber is 3-8 parts by weight, the content of rhizoma acori graminei is that 1-5.5 parts by weight, goldleaf contain Amount is 0.01-0.03 parts by weight, the content of fructus alpiniae oxyphyllae is 3-8 parts by weight, the content of semen ziziphi spinosae is 3-8 parts by weight, fructus schisandrae Content be 3-8 parts by weight, the content of lotus nut is 3-8 parts by weight, the content of walnut kernel is 3-8 parts by weight, the content of cape jasmine is 1-5 parts by weight, the content of sweet wormwood are 0.5-4 parts by weight, the content of humus flava usta is 1-5 parts by weight, the content of Radix Glycyrrhizae is 0.5-4 weight Measure part.
A kind of preferred embodiment according to the present invention, the total weight of the Chinese medicine composition relative to 100 parts by weight, The content of the hollyhock essence is 8 parts by weight, the content of black hyacinth bean is 8 parts by weight, the content of uncaria is that 8 parts by weight, Rhizoma Gastrodiae contain Amount is 6 parts by weight, the content of peach kernel is 6 parts by weight, the content of safflower is 6 parts by weight, the content of fushen is 6 parts by weight, Radix Polygalae Content be 5.5 parts by weight, the content of amber is 5.5 parts by weight, the content of rhizoma acori graminei is 4.5 parts by weight, the content of goldleaf is 0.04 parts by weight, the content of fructus alpiniae oxyphyllae are 5.5 parts by weight, the content of semen ziziphi spinosae is 5.5 parts by weight, the content of fructus schisandrae is 5.5 parts by weight, the content of lotus nut are 5.5 parts by weight, the content of walnut kernel is 5.5 parts by weight, the content of cape jasmine is 2.7 weight Part, the content of sweet wormwood be 1.8 parts by weight, the content of humus flava usta is 2.7 parts by weight, the content of Radix Glycyrrhizae is 1.8 parts by weight.
According to the present invention, the pharmacological action of each bulk pharmaceutical chemicals of the Chinese medicine composition and side's solution are as follows:
The hollyhock essence is root, leaf, flower and the kind of Malvaceae hollyhock platymiscium hollyhock (Althaearosea (L.) Cavan) At least one of son.With treating stranguria, the effect of detumescence, removing toxic substances, it is usually used in controlling stranguria syndrome, swollen ulcer drug, the burning hot wound of soup.
The black hyacinth bean is the leaf and kind of dicotyledon medicine leguminous plant Dolichos lablab (DolichoscultatusThunb.) Son, sweet in flavor, tepor.Enter spleen, stomach meridian.Has effects that invigorating spleen, dampness elimination of relieving summer heat, to summer-heat and damp is vomited and diarrhoea, spleen deficiency is vomitted, and inverse, deficiency of food is long It lets out, the symptoms such as water stops quenching one's thirst, leukorrhea with reddish discharge and infantile malnutrition have significant improvement result.
The uncaria is madder wort uncaria (Uncariarhynchophylla (Miq.) Miq.exHavil), great Ye Uncaria (Uncariamacrophylla Wall.), uncaria hirsuta (UncariahirsutaHavil.), Uncaria sinensis In (Uncariasinensis (Oliv.) Havil.) and stockless fruit uncaria (UncariasessilifructusRoxb.) extremely A kind of few drying buckle stem branch, sweet-bitter flavor；Cold nature.Have effects that The flat liver of heat-clearing, relieving convulsion and spasm, calm decompression, for The symptoms such as headache and dizziness, dysphoric cold, twitch, pre-eclampsia and hypertension have significant improvement result.
The Rhizoma Gastrodiae is the dry tuber of orchid Rhizoma Gastrodiae (GastrodiaelataBlume), sweet in flavor, mild-natured.Have The effect of calming the liver to stop the wind, relieving convulsion.Have for symptoms such as headache and dizziness, extremity numbness, child convulsion, epilepsy clonus and tetanus Significant improvement result.
The peach kernel is rosaceous plant peach (Prunuspersica (L.) Batsch) or mountain peach (Prunusdavidiana (Carr.) Franch.) dry mature seed, it is bitter, sweet, it is mild-natured；Enter the heart, liver, large intestine channel.It is logical with activating blood circulation and dissipating phlegm, ease constipation Just the effect of.Have for symptoms such as amenorrhea and algomenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, pulmonary abscess acute appendicitis, injury from falling down and dry constipation of intestines asthmas significant Improvement result.
The safflower is the dry flower of compositae plant safflower (Carthamustinctorius L.), and acrid flavour is warm-natured.Have The effect of blood circulation, removing blood stasis and acesodyne.For menostasis, dysmenorrhea, lochia, abdominal mass lump in the abdomen, chest impediment and cardialgia, stasis of blood, chest Coercing the symptoms such as shouting pain, injury from falling down and sore swell and ache curative has significant improvement result.
The hollyhock essence, black hyacinth bean, uncaria, Rhizoma Gastrodiae, peach kernel and safflower are monarch drug in a prescription altogether, and above-mentioned six kinds of substances are with use appropriate Amount can play the role of clearing heat and detoxicating, nourishing yin and purging fire, tranquilizing and allaying excitement than being used cooperatively.
Fushen's Polyporaceae crouch hole platymiscium Poria cocos (Poria cum Radix Pini) dry sclerotia body among Entertain the white portion of pine stump, it is sweet in flavor, light flat.With excreting dampness, invigorating the spleen, calming heart and other effects.For palpitation with fear of having a guilty conscience, amnesia, insomnia, The symptoms such as frightened epilepsy, difficult urination have significant improvement result.
The Radix Polygalae is Polygalaceae polygala Radix Polygalae (Polygala tenuifoliaWilld) or ovum leaf Radix Polygalae The dry root of (Polygala sibirica L.), it is bitter, pungent, it is warm-natured.With tranquilize the mind and promote the intelligence, eliminating the phlegm, detumescence and other effects.For The symptoms tool such as insomnia and dreamful sleep caused by breakdown of the normal physiological coordination between the heart and the kidney, amnesia and pavor, despicable, expectoration is not well, sore swollen toxin and breast swell and pain It is significantly improved effect.
The amber be ancient times pinaceae plant resin burial ground under hydrocarbon made of prolonged condensation, slightly sweet flavor, It is mild-natured.Enter the heart, liver, small intestinl channel.With tranquillizing the mind by relieving convulsion, dissipating stasis and stanching bleeding, promoting diuresis for stranguria and other effects.Infantile convulsion epilepsy, palpitation with fear are lost Dormancy, blood strangury blood urine, urinary obstruction, women's amenorrhoea, postpartum stop the symptoms such as stasis of blood abdominal pain, skin sore and traumatic injuries with significant Improvement result.
The rhizoma acori graminei is the dry rhizome of acorus gramineus araceae plant (Acorustatarinowii Schott), taste It is pungent, bitter, it is warm-natured.Return heart, stomach meridian.With dampness elimination appetizing, slit phlegm of having one's ideas straightened out, inducing resuscitation intelligence development and other effects.For gastral cavity ruffian is not hungry, keep silent under mouth Dysentery, coma epilepsy, which are changed, has significant improvement result with symptoms such as forgetfulness and deafness.
The goldleaf is the paper-like thin slice of gold hammer out, and the original shape state of the gold can be rusty gold, the rusty gold It is generally divided into lode gold (mountain gold) and two kinds of gold dust, lode gold originates in quartz vein, and gold dust originates in alluvium.The goldleaf is arduous, It is mild-natured.With relieving palpitation, tranquilizing the mind, removing toxic substances and other effects.Work is significantly improved for the symptoms such as frightened epilepsy, demented, palpitaition and sore tool With.
The fruit of the fructus alpiniae oxyphyllae zingiberaceous plant intelligence development (AlpiniaoxyphyllaMiq.), acrid flavour, warm-natured spleen.Kidney channel. Saliva, warm kidney astringent sperm contracting urine and other effects are taken the photograph with warming spleen and stopping diarrha.For crymodynia in malaria diarrhea, abdomen, the more salivas of mouth, enuresis with renal asthenia, The symptoms such as frequent urination and spermatorrhea gonorrhoea have significant improvement result.
Above-mentioned fushen, Radix Polygalae, amber, rhizoma acori graminei, goldleaf, six medicine of fructus alpiniae oxyphyllae share as ministerial drug, for assisting monarch drug in a prescription to reinforce Treat main disease or main symptom or for and disease or accompanying symptoms play therapeutic effect, six with amount ratio appropriate with the use of can be into one Step reinforces the effect of clearing heat and detoxicating, nourishing yin and purging fire, mental-tranquilization.
The semen ziziphi spinosae is rhamnaceae plant wild jujube (ZiziphusjujubaMill.var.spinosa (Bunge) Hu ex H.F.Chou dry mature seed), it is sweet in flavor, sour, it is mild-natured；Return liver, gallbladder, the heart channel of Hang-Shaoyin.With nourishing heart tonifying liver, antitoxic heart-soothing and sedative, arrest sweating, Promote the production of body fluid and other effects.There is significant improvement result for symptoms such as neurasthenia, insomnia, dreaminess and night sweat.
The fructus schisandrae is the perennial fallen leaves bejuco Schisandra chinensis (Schisandrachinesis of Magnoliaceae (Turcz.) Baill) dry mature fruit, it is sour, it is warm-natured.Enter lung, kidney channel.With astringing lung-QI nourshing kidney, only saliva hidroschesis, arresting seminal emission are stopped The effect of rushing down, calming the nerves.Work is significantly improved for the symptoms such as empty cough asthma, Diarrhoea, night sweat due to yin deficiency and insomnia forgetfulness tool With.
The lotus nut be spire in the mature seed of nymphaeaceae plant lotus (NelumbonuciferaGaertn.) and Radicle, bitter are cold in nature.Enter the heart, lung, kidney three to pass through.With clear away heart-fire be amusing, tonifying spleen and stopping diarrhea, mental-tranquilization improving eyesight, bowl spares are reposed, are good for Spleen mends stomach, antidiarrheal controlling nocturnal emission with astringent drugs, kidney-nourishing relieving leukorrhea by astringents, nourishing vigour and other effects.For the invasion of pericardium by heat, coma and delirium, breakdown of the normal physiological coordination between the heart and the kidney, mistake The symptoms such as spermatorrhea and blood-head haematemesis of sleeping have significant improvement result.
The walnut kernel is the seed of juglandaceae plant English walnut (Juglansregia), sweet in flavor, warm-natured；Enter lung, kidney channel.Tool There are temperature compensation lung kidney, Dingchuan ease constipation and other effects.For lumbago due to the kidney deficiency, foot is soft, the cold of insufficiency type is breathed with cough have with symptoms such as dry feces it is significant Improvement result.
The cape jasmine is the fruit of madder wort cape jasmine (Gardenia jasminoides Ellis), bitter, cold in nature. Enter the heart, liver, lung, stomach, tri-jiao channel.The cold energy heat-clearing of the cape jasmine, bitter energy eliminating dampness, body gently enter gas, color red blood, under capable of reaching on Have a thorough knowledge of three cokes, and it is hot and suffocating to be apt to clear chest diaphragm.With purging intense heat relieving restlessness, reducing fever and causing diuresis and removing pattogenic heat from the blood and toxic material from the body and other effects.For icteric hepatitis, The symptoms such as bruise, hypertension, diabetes have significant improvement result.
The sweet wormwood is the dry aerial parts of compositae plant artemisia annua (Artemisia annua L.), bitter, pungent, property It is cold.Return liver, gallbladder channel, three burnt, kidney channels.With clear abnormal heat, cool blood except steaming, relieving summer-heat and preventing malaria and other effects.For warm evil impairment of yin, night The symptoms such as hot early cool, fever due to yin deficiency, hectic fever due to yin labor heat, summer-heat evil fever, malaria fever and chills and jaundice with damp-heat pathogen have significant improvement result.
Above-mentioned semen ziziphi spinosae, fructus schisandrae, lotus nut, walnut kernel, cape jasmine, six medicine of sweet wormwood share as adjutant, for assisting monarch, minister Medicine is to reinforce therapeutic effect, or directly treats secondary accompanying symptoms, and restrict monarch, ministerial drug high strong property, or be mitigated or eliminated monarch, The drug of ministerial drug toxicity, at the same can also according to the need of certain diseases, compatibility on a small quantity with monarch drug in a prescription nature and flavor or the opposite and energy of effect Serve in the treatment and coordinates.
The humus flava usta is the sallow soil block for burning the Tu Zaonei bottom centre of firewood or weeds, is overhauling firewood furnace or firewood When fiery, the soil block of sintering is removed, prunes burned black part and impurity also known as humus flava usta with knife.It mainly include silicic acid (H2SiO3), aluminium oxide (Al2O3) and di-iron trioxide (Fe2O3) ingredient, also contain sodium oxide molybdena (Na2O), potassium oxide (K2O), oxygen Change magnesium (MgO), calcium oxide (CaO) and calcium phosphate [Ca3(PO4)2] etc. ingredients.The humus flava usta acrid flavour, slightly warm in nature.Enter spleen, stomach Through.Astringing to arrest bleeding, warming middle energizer to arrest vomiting.
Above-mentioned humus flava usta is to make medicine, can be used as harmonizing drug, is used for coordinating the drug actions of a prescription, priming channel tropism.
The Radix Glycyrrhizae is glycyrrhizic legume (GlycyrrhizauralensisFisch.), swollen fruit Radix The dry root and rhizome of (Glycyrrhizainflata Bat.) or glycyrrhiza glabra (Glycyrrhizaglabra L.), sweet in flavor, It is mild-natured.Return heart enters lung, spleen, stomach meridian.Have effects that tonifying spleen stomach function regulating, Yiqi and vein recovery.In addition, the Radix Glycyrrhizae has priming channel tropism Function, the efficacy of a drug of other medicines can be guided to reach diseased region or a certain passages through which vital energy circulates, play the role of " guide ".
Above-mentioned various raw materials can buy the product cooked on the market, can also be obtained by conventional concocting method It arrives, such as can be made and being dried and being ground into powder commonly used in the art for raw material.Dry method can be Drying is dried naturally, is preferably dried naturally.The method of grinding can for the field of Chinese medicines it is conventional by Chinese medicine grind into powder Method, the condition of grinding preferably makes the average particle size 150-200 mesh of the raw material, more preferably 160-180 mesh.
Chinese medicine composition provided by the invention can be made by mixing the various raw materials.As long as mixed condition It is uniformly mixed various raw materials.
Chinese medicine composition provided by the invention contain acetylcholine, lecithin, sodium succinate, flavones, low sugar, protein, The ingredients such as low fat, microelement, multi-vitamins and cellulose can when each raw material component is used cooperatively at a specific ratio To confused and worried, unwisely, vivotoxin accumulation, dysphoria and insomnia, palpitation and amnesia, dizziness and tinnitus, soreness of waist spermatorrhea, five vexed The symptoms such as heat, dry throat generate good improvement result, especially suitable for refreshment and tranquilization, promote blood oxygen metabolism, improve sleep Quality and the content for reducing toxin caused by the intracorporal rouge poison of people, oxygen poison, the damp and hot malicious and intense strain of chill.
The present invention also provides a kind of aforementioned Chinese medicine composition in preparation for improving sleep quality and substance in vivo metabolism Application in the drug of obstacle.
The present invention also provides a kind of aforementioned Chinese medicine composition in preparation for improving sleep quality and substance in vivo metabolism Application in the food of obstacle.
The present invention also provides a kind of Chinese materia medica preparation, which contains active constituent and auxiliary material, wherein the activity Ingredient is Chinese medicine composition provided by the invention.
The Chinese materia medica preparation provided according to the present invention, on the basis of the total weight of the Chinese materia medica preparation, the active constituent contains Amount can be 10-90 weight %, and the content of the auxiliary material can be 10-90 weight %.Under preferable case, the active constituent Content is 40-60 weight %, and the content of the auxiliary material is 40-60 weight %.
The Chinese materia medica preparation provided according to the present invention can be mixture, pill, particle, syrup, paste, capsule and tablet One of.
The Chinese materia medica preparation provided according to the present invention, the auxiliary material can be common pharmaceutically acceptable auxiliary for Chinese materia medica preparation Material, such as can be at least one of pharmaceutically acceptable carrier, diluent, filler and bonding agent.The carrier includes But it is not limited to starch or derivatives thereof, lactose, polyethylene glycol；The diluent includes but is not limited to starch or derivatives thereof, cream Sugar, sucrose, vegetable oil, wax, fatty acid；Filler includes but is not limited to talcum powder；The auxiliary material can also include as preservative, In lubricant, dispersing agent, corrigent, moisturizer, antioxidant, colorant, stabilizer, buffer and pH adjusting agent at least It is a kind of.
The auxiliary material can also include binder, filler, disintegrating agent, lubricant in other excipient, such as tablet； Wine, vinegar, decoction in medicine pill etc.；Host material in semi-solid preparation ointment, creme；Anti-corrosion in liquid preparation Agent, antioxidant, corrigent, aromatic, cosolvent, emulsifier, solubilizer, osmotic pressure regulator, colorant etc..The auxiliary material structure At drug or antigen, it is inactive substance (such as Arabic gum, syrup, honey, lanolin or starch)；Espespecially in medicinal mixture In have under sufficient amount liquid case, to make mixture toughness, the substance that is added to prepare pill or tablet.Above-mentioned substance The stability being formulated is helped as needed or is helped to improve activity or biological effectiveness or is generated and can connect in the case where oral The mouthfeel or smell received.
A kind of preferred embodiment according to the present invention, when the Chinese materia medica preparation is pill or paste, the auxiliary material is At least one of starch, rye flour and honey.In further preferred situation, the auxiliary material is that weight ratio is 0-10: 100 Starch and honey.
According to the present invention, when the Chinese materia medica preparation be pill when, the preparation method of the pill may include by activity at Divide and auxiliary material mixes, then forms.The mixed temperature can be 100-130 DEG C, preferably 105-110 DEG C, when mixed Between can be 10-60 minutes.The molding method can be using the conventional forming method for being used to prepare pill, such as can be with The Traditional Chinese drug mixture being mixed to form is put into pelletization in pellet processing machine.
According to the present invention, when the Chinese materia medica preparation be paste when, the preparation method of the paste may include by activity at Divide and auxiliary material mixes, then forms.The mixed temperature can be 100-130 DEG C, preferably 105-110 DEG C, when mixed Between can be 10-30 minutes.The molding method can be using the conventional forming method for being used to prepare paste, such as can be with The Traditional Chinese drug mixture being mixed to form is put into Manufacturing medicine extract machine, paste is made.
According to the present invention, when the Chinese materia medica preparation be tablet when, the preparation method of the tablet may include by activity at Divide and auxiliary material mixes, then forms.The mixed temperature can be 100-130 DEG C, preferably 105-110 DEG C, when mixed Between can be 10-30 minutes.The molding method can be using the conventional forming method for being used to prepare tablet, such as can be with The Traditional Chinese drug mixture being mixed to form is put into pelleter in flakes.
According to the present invention, when the Chinese materia medica preparation be mixture when, the preparation method of the mixture may include by activity at Divide and auxiliary material mixes, then successively extracts effective component, concentration and purification process.
According to the present invention it is possible to such as be decocted using various conventional traditional Chinese medicine extyaction methods come effective component extracting Cooking method, water extraction and alcohol precipitation method, salting out method and organic solvent extraction etc., since said extracted method can obtain aforementioned Chinese medicine preparation In main pharmacodynamics ingredient, therefore can have refreshment and tranquilization, promote blood oxygen metabolism, improve sleep quality and reduce human body in Rouge poison, oxygen poison, chill it is damp and hot poison and intense strain caused by toxin content the effect of, to confused and worried, unwisely, internal The symptoms such as toxin accumulation, dysphoria and insomnia, palpitation and amnesia, dizziness and tinnitus, soreness of waist spermatorrhea, dysphoria in chestpalms-soles, dry throat have certain Curative effect.
According to the present invention, the water extraction and alcohol precipitation method may include: and first take water as a solvent to extract medicinal material effective component, then with not Ethyl alcohol with concentration uses the precipitation method to remove the impurity in extracting solution.When being extracted with water, the weight ratio of medicinal material and water can be 1 : 6-10 extracts 1-3 times and combined extract.When being precipitated with alcohol, the aqueous extract of every gram of medicinal material can be 65-80 with 1mL concentration The ethyl alcohol of weight % is precipitated.In general, using the primary water-soluble in the extractable medicinal material out of water extraction and alcohol precipitation method being more than 70% Active constituent.
According to the present invention, the organic solvent extraction may include: commonly used with ethyl acetate, acetic acid, triethylamine etc. it is molten After agent and ethyl alcohol or water are mixed in a certain ratio, the specific effective component in medicinal material is targetedly extracted.By organic molten The extractable higher specific effective component of purity out of agent extraction method.
According to the present invention, again through conventional step concentration, purifying or drying after the Chinese medicine composition effective component extracting Obtain Chinese medical extract.The method being wherein concentrated includes but is not limited to: atmospheric evaporation, reduction vaporization, thin film evaporation, multiple-effect are steamed Hair, the method for purifying includes but is not limited to: method of purification of saltouing, macroporous resin adsorption method of purification, ethanol precipitation method of purification, ion effect Purifying resin method, flocculation sedimentation method of purification, membrane separating and purifying method, polycaprolactam method of purification, silica gel absorption chromatographic purifying etc. are changed, Dry method includes but is not limited to: oven drying method, drum-type seasoning, belt drying method, hygroscopic desiccation method, fluid-bed drying, spray Mist seasoning, hypobaric drying method, freeze-drying, infrared drying, micro-wave drying method etc..
According to the present invention, according to the characteristic of crude drug effective components different in the Chinese medicine composition, different mention can be used Taking technique.
Preferably, each Chinese medicine material of the invention is first processed before extraction, wherein to hollyhock essence, ginkgo leaf, people Ginseng, Radix Astragali, semen coicis, pilose antler, triangle vine, cynomorium songaricum, very little rue, complanate astragalus seed, Cortex Cinnamomi and asarum honey refine laggard leaching of serving a round of liquor to the guests；It is white attached to processing Son and radix glycyrrhizae preparata, which are placed in small fire, to be propagandized hotly 30-60 minutes.
The present invention also provides a kind of aforementioned Chinese materia medica preparation in preparation for improving sleep quality and substance in vivo metabolism barrier The application in drug hindered.
Chinese materia medica preparation provided by the invention has effects that promote substance in vivo metabolism, to confused and worried, unwisely, internal The symptoms such as toxin accumulation, dysphoria and insomnia, palpitation and amnesia, dizziness and tinnitus, soreness of waist spermatorrhea, dysphoria in chestpalms-soles and dry throat, which have, significantly to be changed Kind effect.
Below by embodiment, the present invention will be described in more detail.
The processing method of raw material used in following embodiment is as follows:
Respectively by hollyhock essence, black hyacinth bean, uncaria, Rhizoma Gastrodiae, peach kernel, safflower, fushen, Radix Polygalae, amber, rhizoma acori graminei, goldleaf, benefit Intelligence benevolence, semen ziziphi spinosae, fructus schisandrae, lotus nut, walnut kernel, humus flava usta, cape jasmine, sweet wormwood and Radix Glycyrrhizae are ground to 180 purposes after drying Powder.
Wherein, the specification of every goldleaf is 9.33cm × 9.33cm × 0.12 μm (length × width x thickness), specific gravity 15.6- 18.3, weight 0.02g.
Embodiment 1-5
Embodiment 1-5 is used to prepare the present invention and provides the Chinese medicine composition of object.
Each raw material is mixed according to dosage shown in table 1, composition A1-A5 is made respectively.
Table 1
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5
Chinese medicine composition number A1 A2 A3 A4 A5
Hollyhock essence 14.5g 18.5g 11g 6g 23g
Black hyacinth bean 14.5g 10.5g 18g 23g 6g
Uncaria 14.5g 16.5g 14.5g 8.5g 20.5g
Rhizoma Gastrodiae 11g 9g 11g 20g 5g
Peach kernel 11g 9g 11g 5g 20g
Safflower 11g 11g 9g 5g 5g
Fushen 11g 16g 14g 18g 10g
Radix Polygalae 10g 8g 11g 5g 15g
Amber 10g 9g 9g 15g 5g
Rhizoma acori graminei 8g 6g 6g 4g 5g
Goldleaf 2 1 3 2 2
Fructus alpiniae oxyphyllae 10g 11g 9g 15g 5g
Semen ziziphi spinosae 10g 11g 10g 5g 15g
Fructus schisandrae 10g 8g 9g 11g 5g
Lotus core 10g 9g 11g 8g 12g
Walnut kernel 10g 11g 8g 8g 13g
Cape jasmine 4.75g 5.75g 5.25g 10g 1g
Sweet wormwood 3g 3g 4.5g 0.5g 8g
Humus flava usta 4.75g 5.75g 5.25g 10g 1.5g
Radix Glycyrrhizae 3g 3g 4.5g 4g 6g
Embodiment 6-10
Embodiment 6-10 is used to prepare the pill in Chinese materia medica preparation provided by the invention.
Will starch and honey by weight being heated to 110 DEG C after 1: 10 mixing, then respectively prepared by embodiment 1-5 Drug composition A1-A5 is added in the mixture of starch and honey (wherein, the weight of the mixture of A1-A3 and starch and honey It is 2 than the weight ratio for 1: 4, A4-A5 and the mixture of starch and honey: 1), is boiled 20 minutes at 110 DEG C.Then natural It is cooled to after room temperature to be added in pellet processing machine and ball is made, the weight of every ball is 181 grams to get pill B1-B5.
Embodiment 11-15
Embodiment 11-15 is used to prepare the paste in Chinese materia medica preparation provided by the invention.
Honey is heated to 110 DEG C, Chinese medicine composition A1-A5 prepared by exemplified 1-5 is then added to honey respectively In (wherein, the weight ratio of A1-A3 and honey is 1: 9, A4-A5 and the weight ratio of honey is 7: 1), and 20 points of the tanning at 110 DEG C Clock.It is then added to and impartial fritter is made in Manufacturing medicine extract machine.Every piece of weight is 181 grams to get paste C1-C5.
Experimental example 1-5
Experimental example 1-5 is used to illustrate the effect of Chinese materia medica preparation provided by the invention.
(1) absent-minded, attention can not be concentrated, melancholy does not determine, haves the fidgets, speech logic is chaotic, narration is unclear Patient (physical examination: look indefinite, it is absent-minded, have the fidgets, ask non-answered；Tongue fur: micro- Huang, arteries and veins: heavy, thin, slow, puckery) control Therapeutic effect
Selection 400 with absent-minded, attention can not be concentrated, melancholy does not determine, haves the fidgets, voice is patrolled in various degree 16-65 years old patient for collecting symptom chaotic, that narration is unclear, is randomly divided into 10 treatment groups (every group of 40 patients).Wherein, 5 Pill B1-B5 takes respectively in treatment group, and instructions of taking is once in the morning and once at night 1 ball every time, and boiled water is oral, when taking one section Between after observing effect, compared with before medication, the label that symptom completely disappears is that the substantially reduced label of symptom is symptom The label being not improved is that the therapeutic effect of 5 treatment groups is as shown in table 1-3；Paste is taken respectively by other 5 treatment groups C1-C5, instructions of taking are once in the morning and once at night one piece every time, and boiled water is oral, observing effect after a period of time is taken, with clothes Compared before medicine, the label that symptom completely disappears is, the substantially reduced label of symptom is, the label that symptom is not improved be ×, the therapeutic effect of 5 treatment groups is as shown in Table 2-4.
Table 2 takes effect after 15 days
Table 3 takes effect after 30 days
Table 4 takes effect after 60 days
(2) the aching and tired therapeutic effect felt cold of waist lower limb is shown in soreness of waist spermatorrhea, companion
Selection 250 have the spermatorrhea of the different degrees of soreness of waist, with see waist lower limb it is aching and tired feel cold (physical examination: tongue is red, whitish tongue or It is greasy, rapid pulse is thin) 20-60 years old male patient, be randomly divided into 10 treatment groups (every group of 25 patients).Wherein, 5 therapeutic components Pill B1-B5 is not taken, and instructions of taking is that once in the morning and once at night, 2 ball, boiled water take orally, observe after taking a period of time every time Effect, compared with before medication, the label that symptom completely disappears is, the substantially reduced label of symptom is, symptom is without obviously changing Kind label is that the therapeutic effect of 5 treatment groups is as illustrated in tables 5-6；Paste C1-C5 takes respectively in other 5 treatment groups, clothes It is once in the morning and once at night one piece every time with method, boiled water is oral, observing effect after a period of time is taken, compared with before medication, The label that symptom completely disappears is that the substantially reduced label of symptom is that the label that symptom is not improved is 5 treatments The therapeutic effect of group is as shown in 5-6.
After table 5 takes 30
After table 6 takes 90
(3) to dysphoria in chestpalms-soles, dry throat therapeutic effect
Dysphoria in chestpalms-soles, dry throat 16-55 years old patient of 400 tools is selected, (every group 40 of 10 treatment groups are randomly divided into People).Paste B1-B5 takes respectively in 5 treatment groups, and instructions of taking is once in the morning and once at night one piece every time, and boiled water is oral, clothes With observing effect after a period of time, compared with before medication, the label that symptom completely disappears is, the substantially reduced label of symptom be Δ, the label that symptom is not improved are that the therapeutic effect of 5 treatment groups is as shown in table 7-8；Other 5 treatment groups difference Paste C1-C5 is taken, instructions of taking is once in the morning and once at night one piece every time, and boiled water is oral, observes effect after taking a period of time Fruit, compared with before medication, the label that symptom completely disappears is, the substantially reduced label of symptom is, what symptom was not improved Labeled as ×, the therapeutic effect of 5 treatment groups is as shown in table 7-8.
After table 7 takes 30
After table 8 takes 60
From the measurement result of the above experimental example can be seen that Chinese materia medica preparation provided by the invention for treat it is absent-minded, Attention can not be concentrated, melancholy does not determine, haves the fidgets, sound logical miss, narration is unclear, the soreness of waist is passed out semen, sour with waist lower limb are seen It is tired feel cold, be dysphoria in chestpalms-soles, the therapeutic effect of the symptoms such as dry throat and dry throat it is good, Chinese materia medica preparation provided by the invention can To be effectively improved sleep quality, refreshment and tranquilization promotes blood oxygen, blood lipid metabolism.
The preferred embodiment of the present invention has been described above in detail, still, during present invention is not limited to the embodiments described above Detail within the scope of the technical concept of the present invention can be with various simple variants of the technical solution of the present invention are made, this A little simple variants all belong to the scope of protection of the present invention.
It is further to note that specific technical features described in the above specific embodiments, in not lance In the case where shield, can be combined in any appropriate way, in order to avoid unnecessary repetition, the present invention to it is various can No further explanation will be given for the combination of energy.
In addition, various embodiments of the present invention can be combined randomly, as long as it is without prejudice to originally The thought of invention, it should also be regarded as the disclosure of the present invention.

Claims (10)

1. a kind of Chinese medicine composition, which is characterized in that the Chinese medicine composition contains following raw material: hollyhock essence, black hyacinth bean, uncaria, Rhizoma Gastrodiae, peach kernel, safflower, fushen, Radix Polygalae, amber, rhizoma acori graminei, goldleaf, fructus alpiniae oxyphyllae, semen ziziphi spinosae, fructus schisandrae, lotus nut, walnut kernel, Cape jasmine, sweet wormwood, humus flava usta, Radix Glycyrrhizae, wherein the total weight of the Chinese medicine composition relative to 100 parts by weight, the hollyhock essence Content be 3-15 parts by weight, the content of black hyacinth bean is 3-15 parts by weight, the content of uncaria is 3-15 parts by weight, the content of Rhizoma Gastrodiae For 2-12 parts by weight, the content of peach kernel be 2-12 parts by weight, the content of safflower is 2-12 parts by weight, the content of fushen is 2-12 weight Amount part, Radix Polygalae content be 2-10 parts by weight, the content of amber is 2-10 parts by weight, the content of rhizoma acori graminei be 0.5-8 parts by weight, The content of goldleaf is 0.01-0.05 parts by weight, the content of fructus alpiniae oxyphyllae is 2-10 parts by weight, the content of semen ziziphi spinosae is 2-10 weight Part, the content of fructus schisandrae be 2-10 parts by weight, the content of lotus nut is 2-10 parts by weight, the content of walnut kernel is 2-10 weight Part, the content of cape jasmine be 0.5-7 parts by weight, the content of sweet wormwood is 0.3-6 parts by weight, the content of humus flava usta be 0.5-7 parts by weight, The content of Radix Glycyrrhizae is 0.3-6 parts by weight.
2. Chinese medicine composition according to claim 1, wherein the Chinese medicine composition relative to 100 parts by weight it is total Weight, the content of the hollyhock essence is 5-12 parts by weight, the content of black hyacinth bean is 5-12 parts by weight, the content of uncaria is 5-12 weight Measure part, the content of Rhizoma Gastrodiae is 3-10 parts by weight, the content of peach kernel is 3-10 parts by weight, the content of safflower is 3-10 parts by weight, Fu The content of mind is 3-10 parts by weight, the content of Radix Polygalae is 3-8 parts by weight, the content of amber is 3-8 parts by weight, the content of rhizoma acori graminei It for 1-5.5 parts by weight, the content of goldleaf is 0.01-0.03 parts by weight, the content of fructus alpiniae oxyphyllae is that 3-8 parts by weight, semen ziziphi spinosae contain Amount is 3-8 parts by weight, the content of fructus schisandrae is 3-8 parts by weight, the content of lotus nut is 3-8 parts by weight, the content of walnut kernel is 3-8 parts by weight, the content of cape jasmine are 1-5 parts by weight, the content of sweet wormwood is 0.5-4 parts by weight, the content of humus flava usta is 1-5 weight Part, the content of Radix Glycyrrhizae be 0.5-4 parts by weight.
3. Chinese medicine composition described in any one of -2 according to claim 1, wherein the raw material is powder, average particle size For 150-200 mesh.
4. Chinese medicine composition described in any one of claim 1-3 is in preparation for improving sleep quality and substance in vivo generation Thank to the application in the drug of obstacle.
5. Chinese medicine composition described in any one of claim 1-3 is in preparation for improving sleep quality and substance in vivo generation Thank to the application in the food of obstacle.
6. a kind of Chinese materia medica preparation, which contains active constituent and auxiliary material, which is characterized in that the active constituent is right It is required that Chinese medicine composition described in any one in 1-3.
7. Chinese materia medica preparation according to claim 6, wherein on the basis of the total weight of the Chinese materia medica preparation, it is described activity at The content divided is 10-90 weight %, and the content of the auxiliary material is 10-90 weight %.
8. Chinese materia medica preparation according to claim 7, wherein the content of the active constituent is 40-60 weight %, described auxiliary The content of material is 40-60 weight %.
9. the Chinese materia medica preparation according to any one of claim 6-8, wherein the auxiliary material includes pharmaceutically acceptable load At least one of body, diluent, filler and bonding agent.
10. Chinese materia medica preparation described in any one of claim 6-9 is in preparation for improving sleep quality and substance in vivo metabolism Application in the drug of obstacle.
CN201811547266.2A 2018-12-17 2018-12-17 The application of Chinese medicine composition and Chinese materia medica preparation and they Pending CN109432341A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811547266.2A CN109432341A (en) 2018-12-17 2018-12-17 The application of Chinese medicine composition and Chinese materia medica preparation and they

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811547266.2A CN109432341A (en) 2018-12-17 2018-12-17 The application of Chinese medicine composition and Chinese materia medica preparation and they

Publications (1)

Publication Number Publication Date
CN109432341A true CN109432341A (en) 2019-03-08

Family

ID=65559465

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811547266.2A Pending CN109432341A (en) 2018-12-17 2018-12-17 The application of Chinese medicine composition and Chinese materia medica preparation and they

Country Status (1)

Country Link
CN (1) CN109432341A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748774A (en) * 2005-10-20 2006-03-22 北京阜康仁生物制药科技有限公司 Brain tonifying preparation and new preparing method
CN103550532A (en) * 2013-10-26 2014-02-05 荣成市科学技术情报研究所 Traditional Chinese medicine (TCM) composition for treating palpitation
CN105456582A (en) * 2015-12-15 2016-04-06 赵乾锋 Traditional Chinese medicine for treating depressive disorder and anxiety disorder
CN107050364A (en) * 2017-05-02 2017-08-18 李军 It is a kind of to treat medicine of insomnia and preparation method thereof and application method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748774A (en) * 2005-10-20 2006-03-22 北京阜康仁生物制药科技有限公司 Brain tonifying preparation and new preparing method
CN103550532A (en) * 2013-10-26 2014-02-05 荣成市科学技术情报研究所 Traditional Chinese medicine (TCM) composition for treating palpitation
CN105456582A (en) * 2015-12-15 2016-04-06 赵乾锋 Traditional Chinese medicine for treating depressive disorder and anxiety disorder
CN107050364A (en) * 2017-05-02 2017-08-18 李军 It is a kind of to treat medicine of insomnia and preparation method thereof and application method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
景秀香: "补脑丸治疗失眠健忘的疗效及安全性", 《中国当代医药》 *
王丽: "当归健脑抗衰合剂治疗中风后抑郁症疗效观察", 《中西医结合心脑血管病杂志》 *
金熙胜等: "针灸配合中药治疗不寐证33例", 《实用中医内科杂志》 *

Similar Documents

Publication Publication Date Title
CN102048933B (en) Chinese medicinal composition for treating infantile diarrhea and preparation method thereof
CN104799146A (en) Functional nutritional good composition for improving sub-health and preparation method thereof
CN103652361A (en) Feed for postpartum sow in lactation period of 1-20 days and preparation method thereof
CN104799115A (en) Chicken compound feed and preparation method thereof
CN106035861A (en) Inonotus obliquus substitutional tea with health-care functions and preparation method thereof
CN104367879A (en) Pharmaceutical composition for chickens' internal lesion caused by overexertion and preparation method of pharmaceutical composition
CN103405728B (en) A kind of Chinese medicine composition for the treatment of climacteric syndrome and preparation method thereof
CN104305205B (en) A kind of Semen Cuscutae oral liquid improving immunity and preparation method thereof
CN103690919A (en) Medicine for treating piglet iron-deficiency anemia and preparation method of medicine
CN104208581A (en) Schisandra chinensis health care oral liquid capable of preventing alcoholic liver and preparation method thereof
KR101826737B1 (en) A composition containing herbs extract, and manufacturing method of the same
CN102579896B (en) Natural Chinese herbal medicine anticancer pill
KR20160000695A (en) Herbal-medicine containing dha for recovering fatigue and enhancing memory, and method of manufacturing the same
CN106215118A (en) Antineoplastic health preparation and preparation method thereof
TW202330006A (en) Composition for preventing, improving or alleviating symptoms relating to qi deficiency and/or blood deficiency
CN103933538A (en) Medicine for treating spleen-kidney yang deficiency type cirrhosis ascites and preparation method thereof
CN109224021A (en) Treat diabetes, the health protecting tea of lowering blood pressure and blood fat and preparation method
KR20120024186A (en) A composition of health supplementary food and method thereof
CN104258224A (en) Schisandra chinensis oral solution for treating lung-and-kidney yin-deficiency type chronic bronchitis and preparation method thereof
CN109432341A (en) The application of Chinese medicine composition and Chinese materia medica preparation and they
CN111084878A (en) Biological medicine and medical total nutrient food for lung and respiratory system diseases and preparation method thereof
CN104206597B (en) A kind of schisandra health care tea alleviating YIN-deficiency of the lung and kidney symptom and preparation method thereof
CN109170052A (en) A kind of dendrobium nobile stomach-nourishing health tea and preparation method thereof
CN114712466B (en) Medicine with weight-reducing and beautifying effects and preparation method thereof
CN107034094A (en) A kind of preparation method of channels sootheing and network vessel quickening bee honey health-care wine

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20190308

RJ01 Rejection of invention patent application after publication