CN109432336A - A kind of Uygur medicine herbal-composition and preparation method thereof for treating bronchial asthma - Google Patents

A kind of Uygur medicine herbal-composition and preparation method thereof for treating bronchial asthma Download PDF

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CN109432336A
CN109432336A CN201910018826.3A CN201910018826A CN109432336A CN 109432336 A CN109432336 A CN 109432336A CN 201910018826 A CN201910018826 A CN 201910018826A CN 109432336 A CN109432336 A CN 109432336A
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外力·依米提
帕尔哈提·吐尔逊
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/55Linaceae (Flax family), e.g. Linum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61P11/06Antiasthmatics
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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Abstract

The invention discloses a kind of Uygur medicine herbal-compositions and preparation method thereof for treating bronchial asthma, and the composition includes that the following raw material is made: chamomile, wild alfalfa, barley, Trigonella foenum-graecum, linseed, Hyssopus officinalis, venushair fern, Althaea roseal and rose oil.The present invention is the Uygur medicine herbal-composition for treating bronchial asthma, pass through the synergistic effect of each raw material, change histiocytic physiology, biochemical process, it generates analgesia, detumescence, promote blood and Lymphatic Circulation, enhance autoimmunity, human body is acted on by instrument for circulation of body fluid, plays the role for the treatment of bronchial asthma;Composition of the invention is paste, and application treatment application method is simple, and securely and reliably, no skin irritation, no pain can be widely applied to clinic, the deep welcome by vast Bronchial Asthmas;The preparation method of composition of the invention is simple, the effective component in each raw material can be extracted, play better therapeutic effect.

Description

A kind of Uygur medicine herbal-composition and preparation method thereof for treating bronchial asthma
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of Uygur medicine herbal-composition for treating bronchial asthma And preparation method thereof.
Background technique
Bronchial asthma (Bronchial Asthma, abbreviation asthma) is by various kinds of cell especially mast cell, acidophilus Property granulocyte and T lymphocyte participate in chronic airway inflammation;In susceptible person such inflammation can cause the wheezing of recurrent exerbation, The symptoms such as shortness of breath, uncomfortable in chest and/or cough, mostly occur at night or morning;Such symptom is often accompanied by extensive and changeable expiratory flow Speed is limited, but part natural remission or can alleviate through treatment;Such symptom is also with air flue to a variety of stimulating factor reactivity.
The method for treating bronchial asthma in the prior art mostly uses therapy for oral administration, interior anti-inflammatory drug, and healing time is longer, Disease relapse rate is high, and patient's agony when inputting liquid, the more influence patient of night expectoration normally rests, to daily life band It is inconvenient to come, and easily occurs dependence and drug resistance to drug after healing.Even most of patients needs hospitalization, brings pain to patient Financial burden is generated while bitter, and bronchitis asthma easily causes pulmonary heart disease, chronic obstructive disease of lung, Secondary breathing The sequelae such as failure.
Treating Bronchial Asthma mainly controls symptom by hormone mainly based on doctor trained in Western medicine at present, keeps lung function close Optimum state, patient are easy to produce the dependence to hormone.
For these reasons, the present invention is specifically proposed.
Summary of the invention
In order to solve problem above of the existing technology, the present invention provides a kind of Uygur for treating bronchial asthma Herbal-composition and preparation method thereof is cured, composition of the invention is paste, passes through the synergistic effect of each raw material, thus it is possible to vary people The movement of body body fluid compartments, power and vital essence, the permeability etc. of membranous system change histiocytic physiology, biochemical process, generate Analgesia, promotes blood and Lymphatic Circulation at detumescence, enhances autoimmunity, to mitigate symptom.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of Uygur medicine herbal-composition for treating bronchial asthma, the composition include that the following raw material is made, Chamomile, wild alfalfa, barley, Trigonella foenum-graecum, linseed, Hyssopus officinalis, venushair fern, Althaea roseal and rose oil.
Irascibility is moved back in chamomile mildly bitter flavor, improving eyesight, and treatment insomnia reduces blood pressure, can invigorate, refresh oneself.Enhancing memory Power reduces cholesterol.Bronchitis and asthma can be effectively relieved in expelling phlegm and arresting coughing, caused by the headache that can releive, migraine or flu Courbature, centering and gastric acid, calm nerves are helpful.The caused DOMS of flu can be eliminated, can calm spirit, slow feelings of relaxing Thread promotes sleep quality, can also improve the skin of allergy.Helpful sleep, moist skin, treatment prolonged constipation, eliminate it is nervous, Eye fatigue, moistening lung, health, and can treat anxiety and it is nervous caused by indigestion, and to insomnia, neuralgia and cramp, Enterogastritis is all benefited, mitigates headache.
Bronchus and asthma can be effectively relieved in the sub- swelling and pain relieving of wild alfalfa, anti-inflammatory, clearing lung-heat.
Barley have consumer edema, property sweet in flavor and, can help to remove the greasy feeling in mouth, have shield stomach quench one's thirst, except heat function Effect.
Trigonella foenum-graecum kidney-replenishing, dispellieg cold and dampness.Cold hernia is controlled, abdomen coerces turgor, the disturbance of lower legs due to pathogenic cold and dampness, the kidney deficiency soreness of waist, impotence.
Linseed has good effect for removing respiratory secretions and improving constipation, simultaneously for bronchus Inflammation, flu are also effective in cure.
The effect of Hyssopus officinalis is delivered with heat-clearing, preventing phlegm from forming and stopping coughing.For cold, fever, phlegm-heat cough.
Venushair fern all herbal medicine.Hardship, it is cool.There are clearing heat and promoting diuresis, subdhing swelling and detoxicating, relieving cough and asthma, inducing diuresis for treating strangurtia.For Scrofula, mazoitis, dysentery, snake bite, cough with lung heat, haematemesis, metrorrhagia, postpartum blood stasis, urinary tract infections and calculus, Infection of the upper respiratory tract etc..
The effect of Althaea roseal has and blood hemostasis, detoxicating and resolving a mass.For spitting blood, bleeding from five sense organs or subcutaneous tissue, menorrhalgia, leukorrhea with reddish discharge, two Just obstructed, rubella in children, malaria, ulcer furuncle, wasp and scorpion sting, scald, burn.
Further, according to parts by weight, the composition includes that the following raw material is made: chamomile 25-35 parts by weight, open country The sub- 25-35 parts by weight of clover, barley 25-35 parts by weight, Trigonella foenum-graecum 25-35 parts by weight, linseed 25-35 parts by weight, Hyssopus officinalis 10-20 parts by weight, venushair fern 10-20 parts by weight, Althaea roseal 10-20 parts by weight and rose oil 80-120 parts by weight.
Further, according to parts by weight, the composition includes that the following raw material is made: 30 parts by weight of chamomile, wild lucerne 30 parts by weight of Mu, 30 parts by weight of barley, 30 parts by weight of Trigonella foenum-graecum, 30 parts by weight of linseed, 15 parts by weight of Hyssopus officinalis, venushair fern 100 parts by weight of 15 parts by weight, 15 parts by weight of Althaea roseal and rose oil.
Further, the composition is paste.
The present invention also provides the preparation method of the Uygur medicine herbal-composition of the treatment bronchial asthma described in one kind, Include the following steps:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) other raw materials in addition to rose oil are ground into fine powder, rose oil is then added and is mixed, heating, It is cooling to obtain the paste.Further, 30-50 DEG C is heated in step (2).
Further, Hyssopus officinalis and venushair fern are mixed first after extracting, is that other each raw materials carry out mixed powder It is broken.
Further, the extracting method of Hyssopus officinalis and venushair fern is as follows: 5-7 times of weight will be added in Hyssopus officinalis and venushair fern Water, decocted, recycle volatile matter, decocting liquid and volatile matter are mixed, filtered, concentration is dried, crushed into fine powder, obtains mind The extract of vanilla and venushair fern.
Wherein, the weight of water is 5-7 times of Hyssopus officinalis and venushair fern total weight.
Preparation method of the invention first extracts Hyssopus officinalis and venushair fern, is then mixed with other raw materials Paste, the present inventor have found that the therapeutic effect after extracting Hyssopus officinalis and venushair fern is more preferable, this is because refreshing by a large number of experiments Vanilla and venushair fern decoct by high temperature, and effective component therein adequately releases, and have preferably treatment bronchus heavy breathing The effect of asthma.
Further, the time of decoction is 10-12 hours.
Further, the partial size of fine powder is 100 mesh.
Compared with prior art, the invention has the benefit that
(1) the Uygur medicine herbal-composition for the treatment of bronchial asthma of the invention is made by the synergistic effect of each raw material Histiocytic physiology, biochemical process change, and generate analgesia, detumescence, promote blood and Lymphatic Circulation, enhance autoimmunity, Human body is acted on by instrument for circulation of body fluid, plays the role for the treatment of bronchial asthma;
(2) composition of the invention is paste, and application treatment application method is simple, securely and reliably, not damaged, no pain, It can be widely used in clinic, be well received by the majority of patients;
(3) preparation method of composition of the invention is simple, the effective component in each raw material can be extracted, be played Better therapeutic effect.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work Other embodiment belongs to the range that the present invention is protected.
Embodiment 1
A kind of Uygur medicine herbal-composition for treating bronchial asthma of the present embodiment, the composition include as follows Raw material is made: the sub- 25g of chamomile 25g, wild alfalfa, barley 25g, Trigonella foenum-graecum 25g, linseed 25g, Hyssopus officinalis 10g, venushair fern 10g, Althaea roseal 10g and rose oil 80g.
The composition of the present embodiment is paste, the preparation method is as follows:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) other raw materials in addition to rose oil are ground into fine powder, rose oil is then added and is mixed, is heated to 30 DEG C, the retention time is 2 hours, cooling to obtain the paste.
Embodiment 2
A kind of Uygur medicine herbal-composition for treating bronchial asthma of the present embodiment, the composition include as follows Raw material is made: the sub- 30g of chamomile 30g, wild alfalfa, barley 30g, Trigonella foenum-graecum 30g, linseed 30g, Hyssopus officinalis 15g, venushair fern 15g, Althaea roseal 15g and rose oil 100g.
The composition of the present embodiment is paste, the preparation method is as follows:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) other raw materials in addition to rose oil are ground into fine powder, rose oil is then added and is mixed, is heated to 40 DEG C, the retention time is 1.5 hours, cooling to obtain the paste.
Embodiment 3
A kind of Uygur medicine herbal-composition for treating bronchial asthma of the present embodiment, the composition include as follows Raw material is made;The sub- 35g of chamomile 35g, wild alfalfa, barley 35g, Trigonella foenum-graecum 35g, linseed 35g, Hyssopus officinalis 20g, venushair fern 20g, Althaea roseal 20g and rose oil 120g.
The composition of the present embodiment is paste, the preparation method is as follows:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) other raw materials in addition to rose oil are ground into fine powder, rose oil is then added and is mixed, is heated to 50 DEG C, the retention time is 1 hour, cooling to obtain the paste.
Embodiment 4
The composition and ratio of each raw material of the present embodiment are same as Example 2, and difference is the preparation method of paste Difference, the preparation method is as follows:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) water of 5 times of weight will be added in Hyssopus officinalis and venushair fern, carry out decoction 10h, recycle volatile matter, by decocting liquid and Volatile matter mixing, is filtered, and concentration, being dried, crushed into partial size is 100 targeted fine powders, obtains the extract of Hyssopus officinalis and venushair fern;
(3) by except rose oil with for other raw materials crush, extract with Hyssopus officinalis and venushair fern is uniformly mixed, Rose oil is added, is heated to 40 DEG C, the retention time is 1.5 hours, cooling to obtain the paste.
Embodiment 5
The composition and ratio of each raw material of the present embodiment are same as Example 2, and difference is the preparation method of paste Difference, the preparation method is as follows:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) water of 6 times of weight will be added in Hyssopus officinalis and venushair fern, carry out decoction 11h, recycle volatile matter, by decocting liquid and Volatile matter mixing, is filtered, and concentration, being dried, crushed into partial size is 100 targeted fine powders, obtains the extract of Hyssopus officinalis and venushair fern;
(3) by except rose oil with for other raw materials crush, extract with Hyssopus officinalis and venushair fern is uniformly mixed, Rose oil is added, is heated to 40 DEG C, the retention time is 1.5 hours, cooling to obtain the paste.
Embodiment 6
The composition and ratio of each raw material of the present embodiment are same as Example 2, and difference is the preparation method of paste Difference, the preparation method is as follows:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) water of 7 times of weight will be added in Hyssopus officinalis and venushair fern, carry out decoction 12h, recycle volatile matter, by decocting liquid and Volatile matter mixing, is filtered, and concentration, being dried, crushed into partial size is 100 targeted fine powders, obtains the extract of Hyssopus officinalis and venushair fern;
(3) by except rose oil with for other raw materials crush, extract with Hyssopus officinalis and venushair fern is uniformly mixed, Rose oil is added, is heated to 40 DEG C, the retention time is 1.5 hours, cooling to obtain the paste.
Test example 1
Choosing through clinical diagnosis is patient 1200 of bronchial asthma, and men and women's number is identical, the age 45-55 one full year of life it Between, 6 groups are divided into, sticks three courses for the treatment of of paste of embodiment 1-6 preparation respectively, 7 days as a course for the treatment of, sticks one daily Patch, asthma are calmed down, and symptom disappears to cure, and cure rate is shown in Table 1.
Table 1
Sample Cure rate (%)
Embodiment 1 82
Embodiment 2 85
Embodiment 3 84
Embodiment 4 92
Embodiment 5 93
Embodiment 6 91
As can be seen from the above table, the cure rate of pharmaceutical composition of the present invention is higher, and using first by Hyssopus officinalis and iron wire It is higher that fern extracts rear cure rate.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

1. a kind of Uygur medicine herbal-composition for treating bronchial asthma, which is characterized in that the composition includes as follows Raw material is made, chamomile, wild alfalfa, barley, Trigonella foenum-graecum, linseed, Hyssopus officinalis, venushair fern, Althaea roseal and rose oil.
2. the Uygur medicine herbal-composition for the treatment of bronchial asthma according to claim 1, which is characterized in that according to weight Part is measured, the composition includes that the following raw material is made: the sub- 25-35 parts by weight of chamomile 25-35 parts by weight, wild alfalfa, barley 25-35 parts by weight, Trigonella foenum-graecum 25-35 parts by weight, linseed 25-35 parts by weight, Hyssopus officinalis 10-20 parts by weight, venushair fern 10-20 Parts by weight, Althaea roseal 10-20 parts by weight and rose oil 80-120 parts by weight.
3. the Uygur medicine herbal-composition for the treatment of bronchial asthma according to claim 2, which is characterized in that according to weight Part is measured, the composition includes that the following raw material is made;30 parts by weight of chamomile, wild alfalfa sub 30 parts by weight, 30 weight of barley Part, 30 parts by weight of Trigonella foenum-graecum, 30 parts by weight of linseed, 15 parts by weight of Hyssopus officinalis, 15 parts by weight of venushair fern, 15 parts by weight of Althaea roseal With 100 parts by weight of rose oil.
4. the Uygur medicine herbal-composition for the treatment of bronchial asthma according to claim 1 to 3, feature It is, the composition is paste.
5. a kind of preparation method of the Uygur medicine herbal-composition for the treatment of bronchial asthma as claimed in claim 4, feature It is, includes the following steps:
(1) it is weighed respectively according to the weight of each raw material spare;
(2) other raw materials in addition to rose oil are ground into fine powder, rose oil is then added and is mixed, heats, it is cooling Obtain the paste.
6. preparation method according to claim 5, which is characterized in that step is heated to 30-50 DEG C in (2).
7. preparation method according to claim 5, which is characterized in that mix Hyssopus officinalis and venushair fern extract first Afterwards, it is that other each raw materials carry out co-grinding.
8. preparation method according to claim 7, which is characterized in that the extracting method of Hyssopus officinalis and venushair fern is as follows: will The water of 5-7 times of weight is added in Hyssopus officinalis and venushair fern, is decocted, volatile matter is recycled, decocting liquid and volatile matter are mixed, mistake Filter, concentration, is dried, crushed into fine powder, obtains the extract of Hyssopus officinalis and venushair fern.
9. preparation method according to claim 8, which is characterized in that the time of decoction is 10-12 hours.
10. preparation method according to claim 8, which is characterized in that the partial size of fine powder is 100 mesh.
CN201910018826.3A 2019-01-08 2019-01-08 A kind of Uygur medicine herbal-composition and preparation method thereof for treating bronchial asthma Pending CN109432336A (en)

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Application publication date: 20190308