CN111481633A - Traditional Chinese medicine composition for treating neurasthenia and insomnia - Google Patents

Traditional Chinese medicine composition for treating neurasthenia and insomnia Download PDF

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CN111481633A
CN111481633A CN202010463895.8A CN202010463895A CN111481633A CN 111481633 A CN111481633 A CN 111481633A CN 202010463895 A CN202010463895 A CN 202010463895A CN 111481633 A CN111481633 A CN 111481633A
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insomnia
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chinese medicine
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仲崇允
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254Acanthopanax or Eleutherococcus
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
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    • A61K36/88Liliopsida (monocotyledons)
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Abstract

The invention discloses a traditional Chinese medicine for treating neurasthenia and insomnia, which is prepared from the following raw material medicines in parts by weight: 1.5-3 parts of lotus plumule and schisandra chinensis; 3-9 parts of moldavica dragonhead and gastrodia elata; 6-12 parts of dogbane leaves; 10-20 parts by weight of Taibai tea, acanthopanax and lucid ganoderma; and 15-30 parts by weight of dancing grass, radix pseudostellariae and nostoc commune.

Description

Traditional Chinese medicine composition for treating neurasthenia and insomnia
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for treating neurasthenia and insomnia.
Background
Neurasthenia is a type of neurosis mainly characterized by a weakened brain and body function. It is characterized by easy excitation and fatigue, and is often accompanied by emotional symptoms such as tension, vexation and easy irritation, and physiological dysfunction symptoms such as muscle tension pain and sleep disorder. These symptoms are not secondary to somatic diseases and organic lesions of the brain, nor are they part of any other mental disorder. There may be persistent emotional stress and mental stress in the patient before illness. The western medicine mainly uses oryzanol tablets or anxiolytic and antidepressant drugs to treat neurasthenia, can improve anxiety and depression of patients, also can relax muscles and eliminate body discomfort.
The understanding of insomnia by clinical medicine science is limited at present, but clinical doctors begin to define insomnia according to clinical research, and a sleep disorder department of the neurology conference of the Chinese medical society in 2012 sets up a Chinese adult insomnia diagnosis and treatment guideline according to the existing evidence of evidence, wherein insomnia refers to subjective experience of patients on the condition that sleep time and/or quality are not satisfied and daily social functions are affected.
At present, no specific medicine for treating neurasthenia and insomnia exists.
Disclosure of Invention
The invention aims to improve the defects of the prior art and provide the traditional Chinese medicine composition for treating neurasthenia and insomnia, can effectively improve or even eliminate clinical symptoms of patients, and has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.
Neurasthenia belongs to the categories of depression, insomnia, palpitation and the like in traditional Chinese medicine. Is a neurological disease with various clinical symptoms caused by brain dysfunction due to the long-term overstrain, heavy mental burden or mental trauma of patients. The pathogenesis of this disease is mostly caused by seven emotions with internal injuries, especially the relationship with long-term mental depression, excessive anxiety and mental stress is the most closely related. Emotional internal injury often causes disharmony of qi, blood, yin and yang of the zang-fu organs, thereby causing a series of clinical symptoms. Therefore, it has the actions of soothing liver, purging fire, clearing phlegm-heat, nourishing yin, lowering fire, tonifying heart and spleen, nourishing heart, tranquilizing mind and harmonizing heart and kidney. The body of the human body is regulated on the whole so as to achieve the aim of thorough healing.
Based on the theory, the invention provides a traditional Chinese medicine for treating neurasthenia and insomnia, which is prepared from the following raw material medicines in parts by weight: 1.5-3 parts of lotus plumule and schisandra chinensis; 3-9 parts of moldavica dragonhead and gastrodia elata; 6-12 parts of dogbane leaves; 10-20 parts by weight of Taibai tea, acanthopanax and lucid ganoderma; and 15-30 parts by weight of dancing grass, radix pseudostellariae and nostoc commune.
In a preferred embodiment, the traditional Chinese medicine composition for treating neurasthenia and insomnia consists of the following raw material medicines in parts by weight: lotus plumule and schisandra fruit 3 weight portions; 9 parts of moldavica dragonhead and rhizoma gastrodiae; 12 parts of dogbane leaf; taibai tea, acanthopanax root and ganoderma lucidum 20 weight portions; 30 parts of dancing grass, heterophylly falsestarwort root and gynura divaricata.
Wherein, the dogbane leaf: sweet, bitter and cool. It enters liver meridian. Pacify liver, tranquilize mind, clear heat and induce diuresis. Can be used for treating vertigo due to liver-yang, neurasthenia, palpitation, insomnia due to liver-fire disturbing heart, and hypertension.
Lotus plumule with bitter taste; is cold. Returning to the heart; a lung; the kidney channel. Clearing away heart fire; calming liver fire, stopping bleeding; to arrest spontaneous emission. Can be used for treating vexation and insomnia due to liver fire disturbing heart.
Gastrodia elata: sweet and neutral. It enters liver meridian. Pacify liver, extinguish wind and stop spasm. Can be used for treating headache, vertigo, vexation, insomnia, and neurasthenia due to liver fire disturbing heart. Gastrodine (gastrodine) has effective rates of 89.44% and 86.87% for treating neurasthenia and neurasthenia syndrome. It can also inhibit central excitation caused by caffeine, and enhance sleep time effect of pentobarbital. Gastrodia elata has the functions of improving eyesight and obviously enhancing memory. The gastrodia elata has obvious protection and regulation effects on the brain nervous system of a human.
Radix pseudostellariae: sweet, slightly bitter and neutral. It enters spleen and lung meridians. To replenish qi, invigorate the spleen, promote the production of body fluid and moisten the lung. Can be used for treating spleen deficiency, asthenia, and weakness of spleen and stomach; neurasthenia, palpitation, insomnia, dizziness and amnesia due to deficiency of both heart and spleen.
Acanthopanax root: pungent, slightly bitter and warm. It enters spleen, kidney and heart meridians. The functions are mainly used for replenishing qi to invigorate the spleen, tonifying the kidney and soothing the nerves. It is especially effective in treating yang deficiency of spleen and kidney, asthenia, debilitation, anorexia, soreness of waist and knees, and insomnia and dreaminess due to deficiency of both heart and spleen.
Schisandra chinensis: sour, sweet and warm. It enters lung, heart and kidney meridians. Astringe to arrest discharge, benefit qi and promote the production of body fluid, tonify kidney and calm heart. Can be used for treating spontaneous perspiration, night sweat, thirst due to body fluid consumption, shortness of breath, weak pulse, internal heat, diabetes, palpitation, and insomnia due to disharmony between heart and kidney.
Taibai tea: sweet; bitter; diluting; cooling; entering the lung; the stomach; a core; the liver meridian. Clearing heat and promoting fluid production; refreshing and tranquilizing. Can be used for treating vexation, thirst, neurasthenia, insomnia due to hyperactivity of fire due to yin deficiency, hectic fever due to yin deficiency, hypertension, etc.
Ganoderma lucidum: sweet in taste; flattening; is nontoxic. Entering the lung; a core; a spleen; the kidney channel. Replenishing qi and blood; calming the heart; invigorating spleen and stomach. Can be used for treating neurasthenia, insomnia, amnesia, anorexia, tiredness, short breath, and hyperhidrosis; dizziness; mental fatigue, debilitation, etc.
And (3) bean vermicelli dish: sweet and mild in taste. Moisten lung to arrest cough, nourish heart to calm mind, remove food retention and expel ascaris. Can be used for treating bronchitis, neurasthenia, etc.
And (3) fragrant blue: pungent, bitter and cool. Clear lung-heat, relieve exterior syndrome, cool liver and stop bleeding. Can be used for treating tracheitis, asthma, heart disease, neurasthenia, etc.
Dancing grass: slightly astringent and flat. Tranquilizing, removing blood stasis, promoting tissue regeneration, promoting blood circulation, and relieving swelling. It is indicated for neurasthenia due to blood stasis blocking collaterals.
The invention is prepared from Chinese traditional herbal medicines, and the traditional Chinese medicine for effectively treating neurasthenia and insomnia is formed by orderly matching certain natural extracts with definite components and clear effects according to a plurality of principles of traditional Chinese medicine treatment based on syndrome differentiation and modern medicine.
The invention can be used throughout the whole process of treating neurasthenia and insomnia, treats both symptoms and root causes, is not easy to relapse, is safe and reliable, has no obvious toxic and side effects, is convenient for patients to insist on taking for a long time, has no adverse reaction for the patients after taking the medicine for many years, and tracks the blood examination to be normal.
The traditional Chinese medicine composition has the advantages of easily available raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises for medicine production and quality control; the product has low price and is easy to be accepted by patients.
The traditional Chinese medicine composition has remarkable treatment effect on neurasthenia and insomnia, and clinical experiment results show that the traditional Chinese medicine composition is used for treating neurasthenia and insomnia, one dose of the traditional Chinese medicine composition is taken every day, the traditional Chinese medicine composition is decocted with 100 ml of water and divided into two parts, the medicine composition is taken one part in the morning and at night, one part is taken one month as a treatment course, the effect is achieved in one treatment course, the three treatment courses are obviously improved, and the functions of the six treatment courses are basically cured. The cure rate is 88 percent, and the total effective rate is 100 percent.
The invention also provides an oral preparation prepared from the traditional Chinese medicine composition for treating neurasthenia and insomnia, the oral preparation comprises oral liquid, tablets, capsules, pills and the like, preferably the dosage forms are tablets and capsules, and one dose is taken every day in the morning and at night.
The traditional Chinese medicine composition can be prepared into various dosage forms. For example, the decocted liquid medicine is sterilized and disinfected and then packaged to prepare oral liquid; or concentrating the decoction, oven drying, adding pharmaceutically acceptable adjuvants, and making into tablet, capsule, pill, etc.
The medically acceptable auxiliary materials comprise starch, dextrin, sodium carboxymethylcellulose, polyethylene glycol, calcium hydrophosphate, sodium alginate, potassium sorbate and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.

Claims (4)

1. The traditional Chinese medicine for treating neurasthenia and insomnia is characterized by comprising the following raw material medicines in parts by weight: 1.5-3 parts of lotus plumule and schisandra chinensis; 3-9 parts of moldavica dragonhead and gastrodia elata; 6-12 parts of dogbane leaves; 10-20 parts by weight of Taibai tea, acanthopanax and lucid ganoderma; and 15-30 parts by weight of dancing grass, radix pseudostellariae and nostoc commune.
2. The traditional Chinese medicine for treating neurasthenia and insomnia as claimed in claim 1, which is characterized by comprising the following raw material medicines in parts by weight: lotus plumule and schisandra fruit 3 weight portions; 9 parts of moldavica dragonhead and rhizoma gastrodiae; 12 parts of dogbane leaf; taibai tea, acanthopanax root and ganoderma lucidum 20 weight portions; 30 parts of dancing grass, heterophylly falsestarwort root and gynura divaricata.
3. An oral preparation for treating neurasthenia and insomnia, which is characterized by being prepared from the traditional Chinese medicine composition as claimed in any one of claims 1 or 2.
4. The oral preparation for treating neurasthenia and insomnia according to claim 3, which is characterized by comprising oral liquid, tablets, capsules and pills, preferably oral liquid and tablets.
CN202010463895.8A 2020-05-28 2020-05-28 Traditional Chinese medicine composition for treating neurasthenia and insomnia Pending CN111481633A (en)

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CN202010463895.8A CN111481633A (en) 2020-05-28 2020-05-28 Traditional Chinese medicine composition for treating neurasthenia and insomnia
CN202110568034.0A CN113304227A (en) 2020-05-28 2021-05-25 Traditional Chinese medicine composition for treating neurasthenia and insomnia

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