CN104383245A

CN104383245A - Traditional Chinese medicine mixture for treating yin deficiency and yang excess type insomnia

Info

Publication number: CN104383245A
Application number: CN201410664438.XA
Authority: CN
Inventors: 王正琦
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-11-20
Filing date: 2014-11-20
Publication date: 2015-03-04

Abstract

The invention provides a traditional Chinese medicine mixture for treating yin deficiency and yang excess type insomnia. The traditional Chinese medicine mixture is characterized by being prepared from the following traditional Chinese medicinal raw materials in parts by weight: 20-45 parts of prepared rhizome of adhesive rehmannia, 5-15 parts of glycyrrhiza, 10-25 parts of cortex moutan, 10-25 parts of cochinchinese asparagus root, 5-15 parts of polygala tenuifolia, 10-25 parts of Indian bread with pine, 10-25 parts of angelica sinensis, 10-30 parts of Chinese yam, 5-15 parts of common macrocarpium fruit, 10-30 parts of jujube kernel, 20-45 parts of radix ophiopogonis, 10-30 parts of glossy privet fruit and 10-30 parts of white peony root. According to the traditional Chinese medicine mixture provided by the invention, as the components in the traditional Chinese medicine prescription all adopt natural traditional Chinese medicinal raw materials, the traditional Chinese medicine mixture is convenient and simple in preparation, is wide in traditional Chinese medicine source and is low in cost; the traditional Chinese medicine mixture follows the principle of prescription drugs of the traditional Chinese medicine, and the components are taken by decocting by water. Proven by clinical application, the traditional Chinese medicine mixture is remarkable in curative effect, is reliable in functions and is mild in drug property without toxic and side effects.

Description

A kind of Traditional Chinese drug mixture for the treatment of type of deficiency of YIN leading to hyper activity of YANG insomnia

Technical field:

The present invention relates to technical field of Chinese medicine, particularly a kind of Traditional Chinese drug mixture for the treatment of type of deficiency of YIN leading to hyper activity of YANG insomnia.

Background technology:

The deficiency of YIN refers to the virtual loss of essence and blood or body fluid.Generally in normal state, Yin and Yang are relative equilibriums, condition each other and coordinate.Cloudy gas loss, yang-energy loses restriction, will produce the pathological change of high Sheng, occurs pathologic hyperfunctioning, is called " yang hyperactivity ".Therefore, the deficiency of YIN can cause the high Sheng of yang-energy, and yang hyperactivity then can make cloudy liquid consume, both reciprocal causations.So the common dysphoria with feverish sensation in the chest palms and soles of this disease, irritable etc., this wherein has a sleepless night is exactly the most common, and mostly this insomnia is to occur in the sleep initial stage, show as be difficult to fall asleep, for full night broken sleep, to occur in sleep final, patient revives too early, can not fall asleep again.The paradoxical sleep of these patients is all few, and the arousal reaction of easy evoked brain potential.

Summary of the invention:

Object of the present invention be exactly improve a kind ofly to prepare conveniently, medicine source is wide, cost is low, evident in efficacy, with strong points, the Chinese medicinal formulae for the treatment of hyperactivity of YANG due to deficiency of YIN pattern of syndrome insomnia that has no side effect.

The invention provides following technical scheme:

Treat a Traditional Chinese drug mixture for type of deficiency of YIN leading to hyper activity of YANG insomnia, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Radix Rehmanniae Preparata 20-45 part, Radix Glycyrrhizae 5-15 part, Cortex Moutan 10-25 part, Radix Asparagi 10-25 part, Radix Polygalae 5-15 part, lie prostrate refreshing 10-25 part, Radix Angelicae Sinensis 10-25 part, Rhizoma Dioscoreae 10-30 part, Fructus Corni 5-15 part, Semen Ziziphi Spinosae 10-30 part, Radix Ophiopogonis 20-45 part, Fructus Ligustri Lucidi 10-30 part, Radix Paeoniae Alba 10-30 part.

Formula is preferably:

40 parts, Radix Rehmanniae Preparata, 6 parts, Radix Glycyrrhizae, Cortex Moutan 15 parts, Radix Asparagi 18 parts, Radix Polygalae 10 parts, volt god 15 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Dioscoreae 18 parts, Fructus Corni 8 parts, Semen Ziziphi Spinosae 20 parts, Radix Ophiopogonis 30 parts, Fructus Ligustri Lucidi 15 parts, Radix Paeoniae Alba 15 parts.

Form being described in detail as follows of each raw material of Chinese medicine of the present invention:

Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature.Return liver, kidney channel.There is yin nourishing of enriching blood, the effects such as life essence-filling, marrow-benefitting.Be usually used in blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, the diseases such as metrorrhagia, diseases such as also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, pass out semen, quench one's thirst.Radix Rehmanniae Preparata decoct has gold ground hypertension, the effects such as blood pressure, serum cholesterol and triglyceride.

Radix Glycyrrhizae: sweet in the mouth, property is put down.Return stomach, lung, spleen channel.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effects such as coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, the disease such as strong.This product has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic, anticancer, conditioner body immunity function, arrhythmia, blood fat reducing, anti- atherosclerosis, anticoagulant, the pharmacological action such as antitumor.

Cortex Moutan: bitter in the mouth; Cold nature.GUIXIN; Liver; Kidney; Lung meridian.There is clearing away heat and cooling blood; The diseases such as promoting blood circulation to remove blood stasis.Be usually used in the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The pathogenic bacteria later stage brimful of tears, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; The diseases such as beriberoid pyretic arthralgia.The decoct of this product all has stronger antibacterial action to bacillus subtilis, escherichia coli, Bacillus typhi, Salmonella paratyphi, Bacillus proteus, bacillus pyocyaneus, staphylococcus, Hemolytic streptococcus, streptococcus pneumoniae, vibrio cholera etc., leaf of paeonia suffruticosa ardr. decoct has remarkable antibacterial action to dysentery bacterium, bacillus pyocyaneus and staphylococcus aureus, and its active ingredient is gallic acid.

Radix Asparagi: sweet in the mouth, hardship, cold in nature.Return lung, kidney, stomach, large intestine channel.There is replenishing YIN and removing heat, the effects such as lung moistening nourishing kidney.Be usually used in diseases such as controlling fever due to yin deficiency, lung abscess, quench one's thirst.Radix Asparagi contains asparagine, B-sitosterol, steroid saponin, the composition such as phlegmatic temperament, furfural derivatives.Radix Asparagi has hemocytes increasing, strengthens the effect of reticuloendothelial system phagocytic function and prolongation antibody life period.Water decoction, the ethanol formulation of this product have antitumaous effect to the cancerous cell that the rectal cancer of human body separation, colon cancer, fiber meat are stolen in tumor tissues culture fluid; The breathing of cell to Leukemia Patients and dehydrogenase have certain inhibitory action.Water decoction all has bacteriostasis in various degree to staphylococcus aureus, Diplococcus pneumoniae, dark courageous and upright streptococcus, diphtheria corynebacterium, bacillus pyocyaneus, anthrax bacillus.

Radix Polygalae: bitter in the mouth, pungent, slightly warm in nature.GUIXIN, kidney, lung meridian.There is Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the effects such as detumescence.Be usually used in the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, the diseases such as breast swell and pain.Saponin contained in this product, has the effect of stronger lysed erythrocyte.

Volt god: sweet in the mouth, light, property is put down.GUIXIN, spleen channel.There is mind calming, calm the nerves, the effect such as diuretic.Be usually used in palpitation with fear of having a guilty conscience, forgetful, insomnia, infantile convulsion, the diseases such as dysuria.Laboratory animal, with after Poria cum Radix Pini 10-20g/kg gavage, enters quiet sleepy state, but without sleep phenomenon; For the mice of caffeine sodium benzoate excitement, make lumbar injection with Poria cum Radix Pini's decoct 5g/kg, it can be made calm, and calm rate is 90%, calm index 3.11; If use 20g/kg gavage instead, then calm rate is 85.7%, calm index 1.64.

Radix Angelicae Sinensis: warm in nature, hides sweet, pungent.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effects such as loosening bowel to relieve constipation.Be usually used in the diseases such as blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.This product has antithrombus formation, improve blood circulation, to arrhythmia, there is protection, improve coronary circulation, antiinflammatory, analgesia, blood sugar lowering, reduce Acute Hypoxic Pulmonary Hypertension in Anesthetized, improve detection of glomeruli filtration function and reabsorption function after renal ischaemia, Radix Angelicae Sinensis polysaccharide activates the macrophage in hematopoieticmicroenviron-ment by direct and (or) degradation pathways, lymphocyte etc., also muscular tissue can be stimulated, promote that it produces the hematopoietic regulation factor, and then promotion functions hematopoietic stem cell granular leukocyte macrophage colony becomes the proliferation and differentiation of unit, stimulate the effects such as proliferation of Bone Marrow CFU-GM hemopoietic.

Rhizoma Dioscoreae: sweet in the mouth, property is put down.Return spleen, lung, kidney channel.There is spleen reinforcing nourishing the stomach, the effects such as promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.Be usually used in insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat such as to be quenched one's thirst the disease.Rhizoma Dioscoreae is rich in multivitamin, aminoacid and mineral, can prevent and treat Human Lipid Metabolism abnormal, and arteriosclerosis, to safeguarding that insulin normal function also has certain effect, there is enhancing body immunity, beneficial heart and tranquilizing mind, rather cough Dingchuan, the health-care effects such as slow down aging; Improve the immunity of body, strengthen the phagocytosis of macrophage.In addition, Rhizoma Dioscoreae Aqueous extracts also can eliminate urine protein, mutant cell is had to the effect suppressing to produce.

Fructus Corni: sour in the mouth, puckery, slightly warm in nature.Return liver, kidney channel.Be usually used in liver and kidney tonifying, the effects such as essence astringing and desertion stemming.Be usually used in vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat such as to be quenched one's thirst the disease.This product also has antioxidation, anticancer, inflammation-inhibiting reaction, shock, blood sugar lowering and the effect such as antibacterial.

Semen Ziziphi Spinosae: sweet in the mouth, acid, property is put down.GUIXIN, spleen, liver, gallbladder meridian.There is nourishing conscience, calm the nerves, the effects such as arresting sweating.Be commonly used to restlessness of asrhenia type and insomnia; Palpitation with fear palpitation with a distress feeling; The empty disease such as spontaneous perspiration, night sweat of body.Containing volume fatty oil and protein in this product, and containing sterol, triterpenes, Semen Ziziphi Spinosae saponin, volume vitamin C.In addition, this product also has the effects such as calmness, hypnosis, stable, analgesia, cooling.

Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature.GUIXIN, lung, stomach warp.Have YIN nourishing and the production of body fluid promoting, lung moistening such as to clear away heart-fire at the effect.Be usually used in dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; The diseases such as pharyngeal diphtheria.This product can improve immunologic function; Inhibitory action is had to various bacteria; Pituitary adrenal system function can be strengthened, improve organism adaptation ability; There are arrhythmia and the peripheral vascular effect of expansion; Hypoxia-bearing capability can be improved; There is hypoglycemic activity.

Fructus Ligustri Lucidi: sweet in the mouth, hardship, cool in nature.Return liver, kidney channel.There is nourishing the liver and kidney, the effects such as improving eyesight black hair.Be usually used in vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, the diseases such as poor vision.Fructus Ligustri Lucidi can improve peripheral leukocytes, strengthen reticuloendothelial system phagocytic activity, has the effect strengthening cellular immunization and humoral immunization.There is blood fat reducing again, study of anti-atherogenic effect.Rising effect is had to the leukopenia that tired chemotherapy or radiotherapy cause.The growth of some transplanted tumor of animal can be suppressed.There are heart tonifying, diuresis and hepatoprotective effect; And have cough-relieving, cathartic, the effect such as antibacterial.

The Radix Paeoniae Alba: cool in nature, bitter in the mouth acid, is slightly cold, has blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain.The effects such as astringing YIN to stop sweating, are applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.In this product, contained paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose; Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.In addition, research shows: the phagocytic function of the Radix Paeoniae Alba to macrophage has potentiation.

The invention has the advantages that:

The component of Chinese medicinal formulae of the present invention all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, mild in medicine property and, do not occur toxic and side effects, total effective rate 96%, cure rate reaches 84%.

Detailed description of the invention:

Embodiment 1:

Treat a Traditional Chinese drug mixture for type of deficiency of YIN leading to hyper activity of YANG insomnia, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: 40 parts, Radix Rehmanniae Preparata, 6 parts, Radix Glycyrrhizae, Cortex Moutan 15 parts, Radix Asparagi 18 parts, Radix Polygalae 10 parts, volt god 15 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Dioscoreae 18 parts, Fructus Corni 8 parts, Semen Ziziphi Spinosae 20 parts, Radix Ophiopogonis 30 parts, Fructus Ligustri Lucidi 15 parts, Radix Paeoniae Alba 15 parts.

Embodiment 2:

Treat a Traditional Chinese drug mixture for type of deficiency of YIN leading to hyper activity of YANG insomnia, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: 20 parts, Radix Rehmanniae Preparata, 5 parts, Radix Glycyrrhizae, Cortex Moutan 10 parts, Radix Asparagi 10 parts, Radix Polygalae 5 parts, volt god 10 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Dioscoreae 10 parts, Fructus Corni 5 parts, Semen Ziziphi Spinosae 10 parts, Radix Ophiopogonis 20 parts, Fructus Ligustri Lucidi 10 parts, Radix Paeoniae Alba 10 parts.

Embodiment 3:

Treat a Traditional Chinese drug mixture for type of deficiency of YIN leading to hyper activity of YANG insomnia, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: 35 parts, Radix Rehmanniae Preparata, 10 parts, Radix Glycyrrhizae, Cortex Moutan 20 parts, Radix Asparagi 20 parts, Radix Polygalae 15 parts, volt god 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Dioscoreae 25 parts, Fructus Corni 12 parts, Semen Ziziphi Spinosae 25 parts, Radix Ophiopogonis 35 parts, Fructus Ligustri Lucidi 25 parts, Radix Paeoniae Alba 25 parts.

Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.

Concrete grammar is as follows: each raw material of Chinese medicine of formula is put into container, adds cold water and cover powder, soaks 15-20 minute, then adds water and do not have powder about four finger, decoct.At a simmer before make to decoct with high heat, with slow fire boiling 20-30 minute after boiling; Second decocts, and adds water and does not have powder about two finger, decoct 15-20 minute after water boils.Twice decoction is removed slag extracting juice, merges.300ML was taken before half an hour before sleeping.

Claims

1. treat a Traditional Chinese drug mixture for type of deficiency of YIN leading to hyper activity of YANG insomnia, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Radix Rehmanniae Preparata 20-45 part, Radix Glycyrrhizae 5-15 part, Cortex Moutan 10-25 part, Radix Asparagi 10-25 part, Radix Polygalae 5-15 part, lie prostrate refreshing 10-25 part, Radix Angelicae Sinensis 10-25 part, Rhizoma Dioscoreae 10-30 part, Fructus Corni 5-15 part, Semen Ziziphi Spinosae 10-30 part, Radix Ophiopogonis 20-45 part, Fructus Ligustri Lucidi 10-30 part, Radix Paeoniae Alba 10-30 part.

2., according to a kind of Traditional Chinese drug mixture for the treatment of type of deficiency of YIN leading to hyper activity of YANG insomnia described in claim 1, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: 40 parts, Radix Rehmanniae Preparata, 6 parts, Radix Glycyrrhizae, Cortex Moutan 15 parts, Radix Asparagi 18 parts, Radix Polygalae 10 parts, volt god 15 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Dioscoreae 18 parts, Fructus Corni 8 parts, Semen Ziziphi Spinosae 20 parts, Radix Ophiopogonis 30 parts, Fructus Ligustri Lucidi 15 parts, Radix Paeoniae Alba 15 parts.