CN113876924A

CN113876924A - Traditional Chinese medicine formula for treating depression

Info

Publication number: CN113876924A
Application number: CN202111347159.7A
Authority: CN
Inventors: 何彦生
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-11-15
Filing date: 2021-11-15
Publication date: 2022-01-04

Abstract

The invention discloses a traditional Chinese medicine formula for treating depression, which is prepared from the following raw materials in parts by weight: 30g of prepared rehmannia root, 12g of cassia twig, 15g of bighead atractylodes rhizome, 20g of Chinese magnoliavine fruit, 20g of dwarf lilyturf tuber, 9g of prepared monkshood, 12g of roasted liquorice, 9g of dried ginger, 30g of astragalus root, 15g of epimedium, 15g of morinda officinalis, 15g of ligusticum wallichii, 15g of angelica, 15g of rhizoma cyperi, 10g of fructus amomi, 20g of rhizoma acori graminei and 15g of cortex albiziae. The formula of the invention mainly warms the yang of heart, liver, spleen and kidney, and has the functions of benefiting qi, nourishing blood, regulating qi, promoting blood circulation, eliminating phlegm, resolving stagnation and calming the nerves; is especially suitable for middle-aged and elderly people to treat depression and senile dementia due to yang deficiency.

Description

Traditional Chinese medicine formula for treating depression

Technical Field

The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating depression.

Background

Depression (Depressive Disorder), also known as Depressive Disorder (Major Depressive Disorder MADD), is a common mood Disorder, which is mainly characterized by marked and persistent low mood, thought retardation, cognitive impairment, and hypovolemia. The World Health Organization (WHO) has pointed out that MADD is likely to be the second largest disease after ischemic heart disease by 2020. According to the records of ancient Chinese literature, MADD belongs to depression in the categories of depression syndrome, hysteria, lily disease, depressive syndrome and the like in traditional Chinese medicine, and is a common mood disorder disease. For the treatment of depression, traditional Chinese medical doctors usually treat from the liver, mainly soothe the liver and relieve depression, and treat from Xiaoyao san, Yueju Wan and other prescriptions, and obtain certain curative effect. However, depression is mainly manifested by lowered mood, decreased interest and decreased energy in clinic, i.e. the symptoms of depressed yin, such as tarnish, depressed yin, and fading, are still, medial and descending according to syndrome differentiation, and are due to the category of yin diseases.

At present, because MADD has complex etiology, hidden morbidity and slow course of disease, long-term taking of medicine is needed after the disease, although the curative effect of chemical medicines in the medicine for treating MADD is obvious, the medicine for treating MADD has serious toxic and side effects after long-term taking, has large harm to the body of a patient, is easy to generate stage reaction after stopping taking, is easy to generate dependence after long-term taking, is easy to relapse, and has poor compliance because the proportion of MADD patients willing to accept the medicine taking treatment is only about 10 percent.

Disclosure of Invention

The invention aims to provide a traditional Chinese medicine formula for treating depression, which mainly warms the yang of heart, liver, spleen and kidney, and has the functions of benefiting qi, nourishing blood, regulating qi, promoting blood circulation, eliminating phlegm, resolving stagnation and soothing the nerves; is especially suitable for middle-aged and elderly people to treat depression and senile dementia due to yang deficiency.

In order to solve the technical problems, the invention adopts the following technical scheme:

the invention provides a traditional Chinese medicine formula for treating depression, which is characterized by being prepared from the following raw materials in parts by weight: 30g of prepared rehmannia root, 12g of cassia twig, 15g of bighead atractylodes rhizome, 20g of Chinese magnoliavine fruit, 20g of dwarf lilyturf tuber, 9g of prepared monkshood, 12g of roasted liquorice, 9g of dried ginger, 30g of astragalus root, 15g of epimedium, 15g of morinda officinalis, 15g of ligusticum wallichii, 15g of angelica, 15g of rhizoma cyperi, 10g of fructus amomi, 20g of rhizoma acori graminei and 15g of cortex albiziae.

The taking method comprises the following steps:

the method comprises the following steps: one dose is taken every day by decocting with water. Decocting with water 600ml, and orally administering 200ml each time for 3 times.

The method 2 comprises the following steps: making into tablet, powder, pill or capsule at a certain proportion, and taking 12g each time 3 times daily.

The invention has the beneficial effects that: the formula mainly warms the heart, liver, spleen and kidney, and has the effects of tonifying qi, nourishing blood, regulating qi, promoting blood circulation, eliminating phlegm, resolving stagnation and soothing nerves; is especially suitable for middle-aged and elderly people to treat depression and senile dementia due to yang deficiency.

The following further explains the beneficial effects of the invention by combining the effects of the main components in the invention:

prepared rehmannia root: [ PROPERTIES AND FLAVOUR GUIDING JING ] is sweet and warm. It enters liver and kidney meridians. [ FUNCTIONS ] can nourish yin, tonify blood, replenish vital essence and replenish marrow. Can be used for treating deficiency of liver-yin and kidney-yin, soreness of waist and knees, hectic fever, night sweat, nocturnal emission, internal heat, diabetes, blood deficiency, sallow complexion, cardiopalmus, severe palpitation, menoxenia, metrorrhagia, metrostaxis, hemorrhage, giddiness, tinnitus, and early white beard and hair.

Cassia twig: [ PROPERTIES AND FLAVOUR GUIJING ] is pungent, sweet and warm. It enters heart, lung and bladder meridians. [ FUNCTIONS ] can induce sweat, dispel muscles, warm and dredge meridians, strengthen yang, regulate qi, and calm the adverse flow of qi. Can be used for treating wind-cold type common cold, abdominal psychroalgia, blood cold amenorrhea, arthralgia, phlegm retention, edema, palpitation, and galloping.

White atractylodes rhizome: [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] bitter, sweet and warm. It enters spleen and stomach meridians. [ FUNCTIONS INDICATIONS ] can invigorate spleen, replenish qi, eliminate dampness, promote diuresis, stop sweating, and prevent miscarriage. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion. Tu Bai Zhu strengthens spleen, harmonizes stomach and prevents abortion. Can be used for treating spleen deficiency, anorexia, diarrhea, loose stool, and threatened abortion.

Schisandra chinensis: [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] is sour, sweet and warm. It enters lung, heart and kidney meridians. [ FUNCTIONS INDICATIONS ] has effects of astringing, arresting discharge, invigorating qi, promoting fluid production, invigorating kidney, and calming heart. Can be used for treating chronic cough, asthma, nocturnal emission, enuresis, frequent micturition, chronic diarrhea, spontaneous perspiration, night sweat, thirst due to body fluid consumption, short breath, weak pulse, internal heat, diabetes, palpitation, and insomnia.

Radix ophiopogonis: [ PROPERTIES AND WESTERN CHANNELS ] is sweet, slightly bitter and slightly cold. It enters heart, lung and stomach meridians. [ FUNCTIONS ] can nourish yin, promote the production of body fluid, moisten lung and clear away heart-fire. Can be used for treating dry cough due to lung dryness. Cough due to consumptive disease, thirst due to body fluid consumption, vexation, insomnia, internal heat, diabetes, constipation due to intestinal dryness; and (4) pharyngeal diphtheria.

Preparing monkshood: [ PROPERTIES, WEI GUIJING ] is pungent, sweet and hot. It enters heart, kidney and spleen meridians. [ FUNCTIONS ] can restore yang, restore adverse qi, supplement fire, strengthen yang, and dispel pathogenic wind, cold, and dampness. Can be used for treating yang exhaustion, collapse, cold limbs, slight pulse, sexual impotence, cold womb, psychroalgia of heart and abdomen, vomiting and diarrhea due to deficiency-cold, edema due to yin-cold, affection of exogenous pathogenic factor due to yang deficiency, and arthralgia due to cold-dampness.

And (3) liquorice moxibustion: [ FUNCTIONS ] has effects of nourishing yin and blood, invigorating qi, activating yang, recovering pulse, and stopping palpitation. The traditional Chinese medicine is mainly used for treating heart yin and yang deficiency, and later-aged physicians expand the traditional Chinese medicine to treat consumptive disease, consumptive lung disease, lung dryness and yin injury and other symptoms based on Zhang Zhongjing clinical application.

Dried ginger: [ PROPERTIES, WEI GUIJING ] is pungent and hot. It enters spleen, stomach, kidney, heart and lung meridians. [ FUNCTIONS INDICATION ] Zingiberis rhizoma has effects of warming spleen and stomach, dispelling cold, restoring yang, dredging collaterals, eliminating dampness and eliminating phlegm. Can be used for treating abdominal psychroalgia, emesis, diarrhea, cold limbs, slight pulse, phlegm retention, asthma, and cough.

Astragalus root: [ PROPERTIES AND FLAVOUR GUIDING JING ] is sweet and warm. It enters lung and spleen meridians. [ FUNCTIONS INDICATIONS ] has effects of invigorating qi, consolidating superficial resistance, inducing diuresis, removing toxic substances, expelling pus, healing sore, and promoting granulation. Can be used for treating deficiency of vital energy, asthenia, anorexia, loose stool, collapse of middle-warmer energy, chronic diarrhea, rectocele, hematochezia, metrorrhagia, exterior deficiency, spontaneous perspiration, qi deficiency, edema, carbuncle, cellulitis, intractable ulcer, blood deficiency, sallow complexion, internal heat, and diabetes; proteinuria due to chronic nephritis and diabetes.

Herba Epimedii: [ PROPERTIES AND FLAVOUR GUIJING ] is pungent, sweet and warm. It enters liver and kidney meridians. [ FUNCTIONS ] can tonify kidney yang, strengthen tendons and bones, and dispel wind-damp. Can be used for treating sexual impotence, spermatorrhea, tendons and bones flaccidity, rheumatalgia, numbness and contracture; climacteric hypertension.

Radix morindae officinalis: [ PROPERTIES AND FLAVOUR ] mild in nature and pungent and sweet in flavor. [ FUNCTIONS INDICATION ] has the effects of invigorating kidney yang, and strengthening tendons and bones. It can be used for treating kidney essence deficiency, soreness of waist and knees, cold womb, menoxenia, lower abdomen psychroalgia, and rheumatalgia.

Ligusticum wallichii: [ PROPERTIES, WEI GUIJING ] is pungent and warm. It enters liver, gallbladder and pericardium meridians. [ FUNCTIONS ] can promote blood circulation, promote the circulation of qi, dispel wind, and relieve pain. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia.

Chinese angelica: [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] is sweet, pungent and warm. It enters liver, heart and spleen meridians. [ FUNCTIONS ] can tonify blood, promote blood circulation, regulate menstruation, relieve pain, moisten intestines and relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, superficial infection, pyocutaneous disease. The wine angelica sinensis can activate blood and promote menstruation. Can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.

Rhizoma cyperi: [ PROPERTIES AND WESTERN CHANNELS ] is pungent, slightly bitter, slightly sweet and mild. It enters liver, spleen and triple energizer meridians. [ FUNCTIONS INDICATION ] can promote the circulation of qi, relieve depression, regulate menstruation and relieve pain. Can be used for treating stagnation of qi due to stagnation of liver-qi, chest pain, hypochondrium pain, abdominal distention and pain, dyspepsia, chest and abdominal distention and fullness, hernia due to cold, abdominal pain, breast pain, menoxenia, amenorrhea, and dysmenorrhea.

Amomum fruit: [ PROPERTIES, WEI GUIJING ] is pungent and warm. It enters spleen, stomach and kidney meridians. [ FUNCTIONS INDICATIONS ] can remove dampness, stimulate appetite, warm spleen, arrest diarrhea, regulate qi-flowing, and prevent miscarriage. Can be used for treating damp turbidity obstruction in middle energizer, abdominal distention, inappetence, deficiency-cold of spleen and stomach, emesis, diarrhea, vomiting, and threatened abortion.

Grassleaf sweelflag rhizome: [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] is pungent, bitter and warm. It enters heart and stomach meridians. [ FUNCTIONS INDICATION ] can remove dampness, stimulate appetite, induce resuscitation, eliminate phlegm, refresh mind and promote intelligence. Can be used for treating epigastric fullness, inappetence, dysentery, coma, epilepsy, amnesia, and deafness.

Silktree albizzia bark: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ FUNCTIONS ] can soothe five internal organs, nourish heart, harmonize blood, alleviate pain, improve eyesight, relieve swelling, reunite tendons and grow muscles.

Detailed Description

The technical solutions of the present invention will be described clearly and completely in the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

A traditional Chinese medicine formula for treating depression is prepared from the following raw materials by weight: 30g of prepared rehmannia root, 12g of cassia twig, 15g of bighead atractylodes rhizome, 20g of Chinese magnoliavine fruit, 20g of dwarf lilyturf tuber, 9g of prepared monkshood, 12g of roasted liquorice, 9g of dried ginger, 30g of astragalus root, 15g of epimedium, 15g of morinda officinalis, 15g of ligusticum wallichii, 15g of angelica, 15g of rhizoma cyperi, 10g of fructus amomi, 20g of rhizoma acori graminei and 15g of cortex albiziae.

Compatibility of medicines and curative effect

The prescription uses a large dose of prepared rehmannia root to nourish liver yin, nourish liver blood, reduce deficiency hyperactivity, recover the normal functions of yang qi growth and hair growth to the maximum extent, and is matched with fructus amomi to prevent the fructus amomi from stagnating and obstructing the spleen. The appearance of the patient is the sign of yin deficiency with yang hyperactivity, and the essence is the deficiency of astringing and storing function of yang qi in the state of yang deficiency. The aconite, cassia twig, herba epimedii and morinda officinalis tonify kidney yang (kidney yang is the root of all yang), and the prepared rehmannia root is clinically applied to the yin-middle yang-seeking theory; the cassia twig, the monkshood, the dried ginger and the roasted liquorice warm the lung, the spleen, the heart, the liver and the kidney to normally operate with the function of assisting yang-qi warming, the astragalus and the bighead atractylodes rhizome raise yang and benefit the qi of the lung and the spleen and reduce the generation of phlegm-dampness, and the astragalus and the angelica have the functions of tonifying qi and nourishing blood and have synergistic effect in the compound for warming the kidney-yang and treating depression.

The essence of nourishing yin is to astringe yang qi, and by nourishing yin to nourish yang qi, the latent accumulation of yang qi is to restore its normal physiological function. Liver qi mainly ascends, lung qi mainly descends, and Jinkemu and Zongjin Pingmu are helpful for improving depression (chronic stress) state. Ophiopogon root and Schisandra chinensis fruit have the effects of astringing, descending and lung-qi, and guiding yang-qi to enter kidney. "tonify consumptive disease, nourish five internal organs" of fructus Schisandrae chinensis recorded in Ming Yi Bie Lu, and "impairment, emaciation, tonification deficiency, yin-strengthening, male essence" of fructus Schisandrae chinensis recorded in Ben Cao Jing Shu. The effects of the schisandra chinensis such as 'tonifying consumptive disease', 'nourishing five internal organs', 'tonifying deficiency' and 'benefiting man essence' are to regulate the running state of yang qi.

Depression affects smooth qi and blood circulation, the ligusticum wallichii, the angelica and the rhizoma cyperi regulate qi, activate blood and relieve depression, the rhizoma cyperi can invigorate qi movement of liver and spleen, the fructus amomi can eliminate dampness and stimulate appetite, the rhizoma acori graminei can resuscitate and reduce phlegm and dampness; acorus gramineus soland and cortex albiziae can nourish heart, tranquilize mind and relieve depression.

Clinical trials applying the present invention:

100 patients with depression, 50 patients with senile dementia and 50 patients with 100 patients with age 15-80.

The treatment method comprises the following steps: is formulated into tablet, powder, pill or capsule at a certain proportion, and is administered orally at a dose of 12g 3 times a day for 1 year.

Diagnostic criteria for depression

And (3) curing: the feeling of anxiety and depression disappears.

The method has the following advantages: the feeling of anxiety and depression is relieved.

And (4) invalidation: anxiety and depression did not have any relief.

As a result: 50 testers cure 40, 5 effective parts and the effective rate is 90%.

Diagnostic criteria for senile dementia

The method has the following advantages: the decline in cognitive function slows.

And (4) invalidation: cognitive decline was not improved.

As a result: 50 testers, 35 effective, the effective rate is 70%.

It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims

1. The traditional Chinese medicine formula for treating depression is characterized by being prepared from the following raw materials in parts by weight: 30g of prepared rehmannia root, 12g of cassia twig, 15g of bighead atractylodes rhizome, 20g of Chinese magnoliavine fruit, 20g of dwarf lilyturf tuber, 9g of prepared monkshood, 12g of roasted liquorice, 9g of dried ginger, 30g of astragalus root, 15g of epimedium, 15g of morinda officinalis, 15g of ligusticum wallichii, 15g of angelica, 15g of rhizoma cyperi, 10g of fructus amomi, 20g of rhizoma acori graminei and 15g of cortex albiziae.