CN109432255A - Preparation method, fermenation raw liquid and the application of fermenation raw liquid - Google Patents
Preparation method, fermenation raw liquid and the application of fermenation raw liquid Download PDFInfo
- Publication number
- CN109432255A CN109432255A CN201811503557.1A CN201811503557A CN109432255A CN 109432255 A CN109432255 A CN 109432255A CN 201811503557 A CN201811503557 A CN 201811503557A CN 109432255 A CN109432255 A CN 109432255A
- Authority
- CN
- China
- Prior art keywords
- mass parts
- raw liquid
- fermenation raw
- vinegar
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/648—Myriapods, e.g. centipedes or millipedes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Insects & Arthropods (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of preparation method of fermenation raw liquid, fermenation raw liquid and applications, wherein, a kind of preparation method of fermenation raw liquid includes the following steps: that the tuber of pinellia for taking 300-500 mass parts is ground into powdery, the wheat vinegar that 300-500 mass parts are added, which be sealed by fermentation for the first time, obtains half cooked food, under stirring, the wheat vinegar that 200-300 mass parts are added in half cooked food carries out second and is sealed by fermentation to get fermenation raw liquid.The preparation method of above-mentioned fermenation raw liquid is simple, under the action of wheat vinegar.Through secondary seal fermentation process, tuber of pinellia swelling and pain relieving can be given full play of, sterilize anti-inflammatory effect, fermenation raw liquid of the invention is on the basis of many years practical application, through repetition test, it filters out by the tuber of pinellia and wheat vinegar, and the two fermented fermenation raw liquid obtained under proportion combination range of the invention has good effect to a variety of refractory skins are treated.
Description
Technical field
The present invention relates to treating skin disease technical fields, preparation method, proferment more particularly to a kind of fermenation raw liquid
Liquid and application.
Background technique
Skin disease be skin by the influence of internal and external factor after, form, structure and function change, generate pathology
Process, and various clinical manifestations are generated accordingly.Skin disease is also the common disease for seriously affecting health of people, common skin
Disease has psoriasis, venereal disease, eczema, dermatitis, neurodermatitis, anaphylaxis erythema, scabies, whelk, tinea of feet and hands, onychomycosis, piebald
Tinea, ringworm of the body, jock itch etc..
Traditional Chinese medicine treats skin disease, and formula has single type or limitation or medicinal material composition compatibility unreasonable,
Or because imperfect to the extraction of its effective component during processing or processing or extraction is unreasonable, not in place, in certain journey
The effect of depth therapy is not achieved on degree, thus treatment is caused to be not thorough easy recurrence.Cure rate is low, is easy recurrent exerbation.
Summary of the invention
Based on this, it is necessary to for traditional problem, provide that a kind of to treat skin disease, tinea pedis, allergic dermatitis effect good
Fermenation raw liquid preparation method, fermenation raw liquid and application.
A kind of preparation method of fermenation raw liquid, the preparation method of the fermenation raw liquid include the following steps:
The tuber of pinellia of 300-500 mass parts is taken to be ground into powdery, the wheat vinegar that 300-500 mass parts are added carries out first time sealing
Fermentation obtains half cooked food, and under stirring, second of the progress of wheat vinegar that 200-300 mass parts are added in half cooked food is close
Seal ferment is to get fermenation raw liquid.
The preparation method of above-mentioned fermenation raw liquid is simple, under the action of wheat vinegar.It, can be abundant through secondary seal fermentation process
It plays tuber of pinellia swelling and pain relieving, sterilize anti-inflammatory effect, fermenation raw liquid of the invention is on the basis of many years practical application, through repeatedly
Test is filtered out by the tuber of pinellia and wheat vinegar, and the two fermented fermenation raw liquid pair obtained under proportion combination range of the invention
Treating a variety of refractory skins has good effect.
The temperature that the first time is sealed by fermentation in one of the embodiments, is 15 DEG C -20 DEG C, the first time sealing
The time of fermentation is 160h-240h.
Described second temperature being sealed by fermentation is 20 DEG C -25 DEG C in one of the embodiments, second of sealing
The time of fermentation is 80h-100h.
Described second relative humidity being sealed by fermentation is 75%-80% in one of the embodiments,.
The present invention also provides a kind of fermenation raw liquids.
A kind of fermenation raw liquid is prepared using preparation method described in any embodiment of the present invention.
The present invention also provides a kind of fermenation raw liquids to treat the application in dermopathic drug in preparation.
The present invention also provides a kind of Chinese medicine compositions for the treatment of venereal.
A kind of Chinese medicine composition for the treatment of venereal, the raw material components of the Chinese medicine composition of the treating venereal include the present invention
Fermenation raw liquid described in any embodiment, wheat vinegar, the rose of Sharon and julid, wherein the fermenation raw liquid is 100-200 mass parts, described
Wheat vinegar is 180-360 mass parts, the rose of Sharon is 30-50 mass parts, the julid is 25-50 mass parts.
The Chinese medicine composition of above-mentioned treating venereal can effective treating venereal.
The present invention also provides a kind of Chinese medicine compositions for treating allergic dermatitis.
A kind of Chinese medicine composition for treating allergic dermatitis, the raw material group of the Chinese medicine composition of the treatment allergic dermatitis
Dividing includes fermenation raw liquid, wheat vinegar and julid described in any embodiment of the present invention, wherein the fermenation raw liquid is 100-200 mass
Part, the wheat vinegar are 700-750 mass parts, the julid is 55-110 mass parts.
The Chinese medicine composition of above-mentioned treatment allergic dermatitis can effectively treat allergic dermatitis.
The present invention also provides a kind of Chinese medicine compositions for treating tinea pedis.
The raw material components of a kind of Chinese medicine composition for treating tinea pedis, the Chinese medicine composition of the treatment tinea pedis include the present invention
Fermenation raw liquid described in any embodiment, wheat vinegar, the rose of Sharon and rice vinegar, wherein the fermenation raw liquid is 100-200 mass parts, described
Wheat vinegar is 1600-1900 mass parts, the rose of Sharon is 25-50 mass parts, the rice vinegar is 100-200 mass parts.
The Chinese medicine composition of above-mentioned treatment tinea pedis can effectively treat tinea pedis.
The present invention also provides a kind of Chinese medicine compositions for treating pityriasis rosea.
A kind of Chinese medicine composition for treating pityriasis rosea, the raw material components packet of the Chinese medicine composition of the treatment pityriasis rosea
Include fermenation raw liquid described in any embodiment of the present invention, wheat vinegar, the rose of Sharon and julid, wherein the fermenation raw liquid is 100-200 mass
Part, the wheat vinegar are 680-720 mass parts, the rose of Sharon is 100-150 mass parts, the julid is 10-15 mass parts.
The Chinese medicine composition of above-mentioned treatment pityriasis rosea can effectively treat pityriasis rosea.
Detailed description of the invention
Fig. 1 is the effect contrast figure that tinea pedis patient is pretherapy and post-treatment in one embodiment of the invention；
Fig. 2 is the effect contrast figure that psoriatic is pretherapy and post-treatment in one embodiment of the invention.
Note: left figure is skin effects figure before tinea pedis patient treats in Fig. 1, and right figure is skin after tinea pedis patient treatment in Fig. 1
Effect picture；Four width figures be skin effects figure before psoriatic treats above in Fig. 2, and three width figures are psoriasis trouble below in Fig. 2
Skin effects figure after person's treatment.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, with reference to the accompanying drawing to the present invention
Specific embodiment be described in detail.Many details are explained in the following description in order to fully understand this hair
It is bright.But the invention can be embodied in many other ways as described herein, those skilled in the art can be not
Similar improvement is done in the case where violating intension of the present invention, therefore the present invention is not limited by the specific embodiments disclosed below.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention
The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool
The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term " and or " used herein includes one or more phases
Any and all combinations of the listed item of pass.
A kind of preparation method of fermenation raw liquid, the preparation method packet of the fermenation raw liquid are provided in one embodiment of the invention
Include following steps:
The tuber of pinellia of 300-500 mass parts is taken to be ground into powdery, the wheat vinegar that 300-500 mass parts are added carries out first time sealing
Fermentation obtains half cooked food, and under stirring, second of the progress of wheat vinegar that 200-300 mass parts are added in half cooked food is close
Seal ferment is to get fermenation raw liquid.
It takes the tuber of pinellia of 350-450 mass parts to be ground into powdery in one of the embodiments, 400-500 mass parts is added
Wheat vinegar carry out for the first time be sealed by fermentation obtain half cooked food, under stirring, in half cooked food be added 200-260 mass
The wheat vinegar of part carries out second and is sealed by fermentation to get fermenation raw liquid.
Tuber of pinellia effective component is complicated, mainly there is alkaloids, amino acid, organic acid, β-sterol etc., and alkaloids is half
The main component of summer pharmacological activity proves that it is anti-with preventing or arresting vomiting, antibechic, eliminating the phlegm, swelling and pain relieving, sterilization in modern pharmacological research
Scorching, antitumor and raising memory effect.Nature is stablized, good water solubility, is not easy to be destroyed decomposition under general condition.
Fiber in wheat vinegar can promote excreting for noxious material, in addition, the active element selenium in wheat vinegar, in skin
On a kind of unstable " metal-selenium-albumen " compound can be formed with metal bonding, facilitate the discharge of internal noxious material.
It is believed that wheat vinegar has the health-care effects such as heat-clearing and fire-reducing, relieving dyspepsia, cool blood detumescence in Chinese medicine, have very high edible
Value and medical value.Wheat vinegar in the present invention preferably is selected from malt vinegar, and the degree of malt vinegar is selected from 4-6 degree.
The temperature that the first time is sealed by fermentation in one of the embodiments, is 15 DEG C -20 DEG C, the first time sealing
The time of fermentation is 160h-240h.At this temperature and fermentation time, stimulating component needle-like calcium oxalate crystal tip in the tuber of pinellia to needle
Body gradually corrodes, and strips off, rust, until disappearing, makes needle content from 2% dramatic decrease to 1% or less.Preferably, described
The temperature being sealed by fermentation for the first time is 16 DEG C -18 DEG C, and the time that the first time is sealed by fermentation is 180h-200h.Further,
The temperature that the first time is sealed by fermentation is 17 DEG C, and the time that the first time is sealed by fermentation is 190h.
Second of main function being sealed by fermentation is that half cooked food is made further to ferment, and decomposes the acid solution in wheat vinegar, makes half
Effective component alkaloids, amino acid, organic acid, β-sterol more alcohol in summer is ripe, makes the effective substance in the tuber of pinellia and wheat vinegar
Matter is sufficiently discharged into fermentation liquid.
Described second temperature being sealed by fermentation is 20 DEG C -25 DEG C in one of the embodiments, second of sealing
The time of fermentation is 80h-100h.It is discharged into the active principle in the tuber of pinellia and wheat vinegar sufficiently in fermentation liquid.Preferably,
Described second temperature being sealed by fermentation is 22 DEG C -24 DEG C, and described second time being sealed by fermentation is 85h-95h.Further
Ground, described second temperature being sealed by fermentation is 23 DEG C, and described second time being sealed by fermentation is 90h.
Described second relative humidity being sealed by fermentation is 75%-80% in one of the embodiments,.It is appreciated that
Described second relative humidity being sealed by fermentation is 75%, 78% or 80%.
The preparation method of above-mentioned fermenation raw liquid is simple, under the action of wheat vinegar.It, can be abundant through secondary seal fermentation process
It plays tuber of pinellia swelling and pain relieving, sterilize anti-inflammatory effect, fermenation raw liquid of the invention is on the basis of many years practical application, through repeatedly
Test, filters out with the tuber of pinellia and wheat vinegar and the two fermented fermenation raw liquid obtained under proportion combination range of the invention
There is good effect to a variety of refractory skins are treated.
A kind of fermenation raw liquid is prepared using preparation method described in any of the above-described embodiment.
A kind of fermenation raw liquid is also provided in one embodiment of the invention and treats the application in dermopathic drug in preparation.Include
The drug of fermenation raw liquid described in any embodiment of the present invention can effectively treat multiple dermatosis, including but not limited to venereal disease, foot
Tinea, psoriasis, pityriasis rosea, epifolliculitis, eczema, allergic dermatitis etc..
The present invention also provides a kind of Chinese medicine compositions for the treatment of venereal.
A kind of Chinese medicine composition for the treatment of venereal, the raw material components of the Chinese medicine composition of the treating venereal include the present invention
Fermenation raw liquid described in any embodiment, wheat vinegar, the rose of Sharon and julid, wherein the fermenation raw liquid is 100-200 mass parts, described
Wheat vinegar is 180-360 mass parts, the rose of Sharon is 30-50 mass parts, the julid is 25-50 mass parts.
The raw material components of the Chinese medicine composition of the treating venereal include following mass parts in one of the embodiments,
Each component, the fermenation raw liquid is 120-180 mass parts, the wheat vinegar is 200-300 mass parts, the rose of Sharon is 34-40 matter
Measure part, the julid is 30-50 mass parts.
The raw material components of the Chinese medicine composition of the treating venereal include following mass parts in one of the embodiments,
Each component, the fermenation raw liquid is 150 mass parts, the wheat vinegar is 2060 mass parts, the rose of Sharon is 3540 mass parts, described
Julid is 40 mass parts.
The rose of Sharon (scientific name: Hibiscus syriacus), one kind of Malvaceae Hibiscus are a kind of very common flower garden fillings
The wooden seeds of flowering plants.Shrub althea flower has the effect of clearing heat and cooling blood, removing toxicity for detumescence, and root skin and stem micromicro clearing heat and promoting diuresis, desinsection are antipruritic.Especially kill
Go out trichomonas vaginalis, Candida albicans, gonococcus, Chlamydia, microspironema pallidum, and destroying AIDS virus surface antigen etc. has very
Good drug effect.
Julid, main function have detoxication, have extraordinary therapeutic effect to skin disease, venereal disease containing carbuncle swells, carbuncle.
Julid shows broad-spectrum antibacterial action, has killing effect to bacterium.
A kind of Chinese medicine composition for treating allergic dermatitis is also provided in one embodiment of the invention.
A kind of Chinese medicine composition for treating allergic dermatitis, the raw material group of the Chinese medicine composition of the treatment allergic dermatitis
Dividing includes fermenation raw liquid, wheat vinegar and julid described in any embodiment of the present invention, wherein the fermenation raw liquid is 100-200 mass
Part, the wheat vinegar are 700-750 mass parts, the julid is 55-110 mass parts.
A kind of Chinese medicine composition for treating allergic dermatitis in one of the embodiments, the treatment allergic dermatitis
Chinese medicine composition raw material components include any embodiment of the present invention described in fermenation raw liquid, wheat vinegar and julid, wherein the hair
Ferment stoste is 120-180 mass parts, the wheat vinegar is 720-750 mass parts, the julid is 65-110 mass parts.
A kind of Chinese medicine composition for treating allergic dermatitis in one of the embodiments, the treatment allergic dermatitis
Chinese medicine composition raw material components include any embodiment of the present invention described in fermenation raw liquid, wheat vinegar and julid, wherein the hair
Ferment stoste is 140 mass parts, the wheat vinegar is 740 mass parts, the julid is 100 mass parts.
A kind of preparation method of Chinese medicine composition for treating allergic dermatitis is also provided in one embodiment of the invention, is wrapped
It includes: fermenation raw liquid 100-200 mass parts, the wheat vinegar 700-750 mass parts, julid that any embodiment of the present invention is prepared
55-110 mass parts are uniformly mixed, cryo-conservation.
The Chinese medicine composition of above-mentioned treatment allergic dermatitis can effectively treat allergic dermatitis.
A kind of Chinese medicine composition for treating tinea pedis is also provided in one embodiment of the invention.
The raw material components of a kind of Chinese medicine composition for treating tinea pedis, the Chinese medicine composition of the treatment tinea pedis include the present invention
Fermenation raw liquid described in any embodiment, wheat vinegar, the rose of Sharon and rice vinegar, wherein the fermenation raw liquid is 100-200 mass parts, described
Wheat vinegar is 1600-1900 mass parts, the rose of Sharon is 25-50 mass parts, the rice vinegar is 100-200 mass parts.
A kind of Chinese medicine composition for treating tinea pedis in one of the embodiments, the Chinese medicine composition of the treatment tinea pedis
Raw material components include any embodiment of the present invention described in fermenation raw liquid, wheat vinegar, the rose of Sharon and rice vinegar, wherein the fermenation raw liquid
For 120-180 mass parts, the wheat vinegar be 1800-1900 mass parts, the rose of Sharon is 30-50 mass parts, the rice vinegar is
140-160 mass parts.
A kind of Chinese medicine composition for treating tinea pedis in one of the embodiments, the Chinese medicine composition of the treatment tinea pedis
Raw material components include fermenation raw liquid, wheat vinegar, the rose of Sharon and rice vinegar of the present invention, wherein the fermenation raw liquid be 140 mass
Part, the wheat vinegar are 1850 mass parts, the rose of Sharon is 40 mass parts, the rice vinegar is 150 mass parts.
A kind of preparation method of Chinese medicine composition for treating tinea pedis is also provided in one embodiment of the invention comprising: by institute
State fermenation raw liquid 100-200 mass parts, the wheat vinegar 1600-1900 mass parts, the rose of Sharon 25-50 mass parts and the rice vinegar
100-200 mass parts are uniformly mixed, cryo-conservation.
Wherein, rice vinegar is mainly used for foot caused by inhibiting dermatophyte, yeast-like fungus and non-skin tinea bacterium property filamentous fungi
Tinea disease (being commonly called as tinea pedis).
The Chinese medicine composition of above-mentioned treatment tinea pedis can effectively treat tinea pedis.
A kind of Chinese medicine composition for treating pityriasis rosea is also provided in one embodiment of the invention.
A kind of Chinese medicine composition for treating pityriasis rosea, the raw material components packet of the Chinese medicine composition of the treatment pityriasis rosea
Include fermenation raw liquid described in any embodiment of the present invention, wheat vinegar, the rose of Sharon and julid, wherein the fermenation raw liquid is 100-200 mass
Part, the wheat vinegar are 680-720 mass parts, the rose of Sharon is 100-150 mass parts, the julid is 10-15 mass parts.
A kind of Chinese medicine composition for treating pityriasis rosea in one of the embodiments, in the treatment pityriasis rosea
The raw material components of drug composition include fermenation raw liquid, wheat vinegar, the rose of Sharon and julid of the present invention, wherein the fermenation raw liquid is
120-180 mass parts, the wheat vinegar are 700-720 mass parts, the rose of Sharon is 120-150 mass parts, the julid is 10-14
Mass parts.
A kind of Chinese medicine composition for treating pityriasis rosea in one of the embodiments, in the treatment pityriasis rosea
The raw material components of drug composition include fermenation raw liquid, wheat vinegar, the rose of Sharon and julid described in any embodiment of the present invention, wherein described
Fermenation raw liquid is 150 mass parts, the wheat vinegar is 710 mass parts, the rose of Sharon is 140 mass parts, the julid is 12 mass
Part.
The Chinese medicine composition of above-mentioned treatment pityriasis rosea can effectively treat pityriasis rosea.
A kind of preparation method of Chinese medicine composition for treating pityriasis rosea is also provided in one embodiment of the invention comprising will
Fermenation raw liquid 100-200 mass parts described in any embodiment of the present invention, the wheat vinegar 680-720 mass parts, the rose of Sharon 100-
150 mass parts, the julid 10-15 mass parts are uniformly mixed, cryo-conservation.
In order to which objects and advantages of the present invention are more clearly understood, the present invention is carried out with reference to embodiments further
It is described in detail.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not intended to limit the present invention.
Embodiment 1
A kind of preparation method of fermenation raw liquid comprising:
The tuber of pinellia of 300 mass parts is taken to be ground into powdery, 5 degree of malt vinegars that 300 mass parts are added carry out sealing hair for the first time
Ferment obtains half cooked food, and under stirring, the wheat vinegar that 200 mass parts are added in half cooked food carries out second of sealing hair
Ferment is to get fermenation raw liquid.The temperature that first time is sealed by fermentation is 15 DEG C, and the time that the first time is sealed by fermentation is
160h.Described second temperature being sealed by fermentation is 20 DEG C, and described second time being sealed by fermentation is 80h, described second
The relative humidity of sealing and fermenting is 75%.
Embodiment 2
A kind of preparation method of fermenation raw liquid comprising:
The tuber of pinellia of 450 mass parts is taken to be ground into powdery, 5 degree of malt vinegars that 450 mass parts are added carry out sealing hair for the first time
Ferment obtains half cooked food, and under stirring, the wheat vinegar that 240 mass parts are added in half cooked food carries out second of sealing hair
Ferment is to get fermenation raw liquid.The temperature that first time is sealed by fermentation is 20 DEG C, and the time that the first time is sealed by fermentation is
180h.Described second temperature being sealed by fermentation is 20 DEG C, and described second time being sealed by fermentation is 80h, described second
The relative humidity of sealing and fermenting is 78%.
Embodiment 3
A kind of preparation method of the Chinese medicine composition for the treatment of venereal: by fermenation raw liquid described in embodiment 1,5 degree of malt vinegars, wood
The rose of Sharon and julid are uniformly mixed, cryo-conservation.Wherein, the fermenation raw liquid is 120 mass parts, the malt vinegar is 180 matter
Measure part, the rose of Sharon is 36 mass parts, the julid is 30 mass parts.
Embodiment 4
A kind of preparation method of the Chinese medicine composition for the treatment of venereal: by fermenation raw liquid described in embodiment 2,5 degree of malt vinegars, wood
The rose of Sharon and julid are uniformly mixed, cryo-conservation.Wherein, the fermenation raw liquid is 180 mass parts, the malt vinegar is 300 matter
Measure part, the rose of Sharon is 46 mass parts, the julid is 45 mass parts.
Embodiment 5
A kind of preparation method of Chinese medicine composition that treating allergic dermatitis comprising following steps:
Fermenation raw liquid described in embodiment 1,5 degree of malt vinegars, the rose of Sharon and julid are uniformly mixed, cryo-conservation.Wherein,
The fermenation raw liquid is 150 mass parts, the malt vinegar is 700 mass parts, the julid is 60 mass parts.
Embodiment 6
A kind of preparation method of Chinese medicine composition that treating allergic dermatitis comprising following steps:
Fermenation raw liquid described in embodiment 2,5 degree of malt vinegars, the rose of Sharon and julid are uniformly mixed, cryo-conservation.Wherein,
The fermenation raw liquid is 200 mass parts, the malt vinegar is 720 mass parts, the julid is 60 mass parts.
Embodiment 7
A kind of preparation method of Chinese medicine composition that treating tinea pedis comprising following steps:
Fermenation raw liquid described in embodiment 1,5 degree of malt vinegars, the rose of Sharon and 5 degree of rice vinegars are uniformly mixed, cryo-conservation.Its
In, the fermenation raw liquid is 160 mass parts, the malt vinegar is 1600 mass parts, the rose of Sharon is 25-50 mass parts, described
Rice vinegar is 120 mass parts.
Embodiment 8
A kind of preparation method of Chinese medicine composition that treating tinea pedis comprising following steps:
Fermenation raw liquid described in embodiment 1,5 degree of malt vinegars, the rose of Sharon and 5 degree of rice vinegars are uniformly mixed, cryo-conservation.Its
In, the fermenation raw liquid is 200 mass parts, the malt vinegar is 1900 mass parts, the rose of Sharon is 25-50 mass parts, described
Rice vinegar is 180 mass parts.
Embodiment 9
A kind of preparation method of Chinese medicine composition that treating pityriasis rosea comprising following steps:
Fermenation raw liquid described in embodiment 1,5 degree of malt vinegars, the rose of Sharon and julid are uniformly mixed, cryo-conservation.Wherein,
The fermenation raw liquid is 170 mass parts, the malt vinegar is 690 mass parts, the rose of Sharon is 120 mass parts, the julid is
12 mass parts.
Embodiment 10
A kind of preparation method of Chinese medicine composition that treating pityriasis rosea comprising following steps:
Fermenation raw liquid described in embodiment 2,5 degree of malt vinegars, the rose of Sharon and julid are uniformly mixed, cryo-conservation.Wherein,
The fermenation raw liquid is 190 mass parts, the malt vinegar is 720 mass parts, the rose of Sharon is 120 mass parts, the julid is
12 mass parts.
Comparative example 1
The Chinese medicine composition only formed with 100 parts of the unfermentable tuber of pinellia and 100 mass parts malt vinegars.
Comparative example 2
The Chinese medicine composition only formed with the unfermentable tuber of pinellia of 100 mass parts and the 100 mass parts tubers of stemona.
Comparative example 3
A kind of preparation method of fermenation raw liquid comprising:
The tuber of pinellia of 100 mass parts is taken to be ground into powdery, 5 degree of malt vinegars that 60 mass parts are added carry out first time sealing and fermenting
Half cooked food is obtained, under stirring, the wheat vinegar that 70 mass parts are added in half cooked food carries out second and is sealed by fermentation,
Up to fermenation raw liquid.The temperature that the first time is sealed by fermentation is 15 DEG C, and the time that the first time is sealed by fermentation is 160h.Institute
The temperature for stating second of sealing and fermenting is 20 DEG C, and described second time being sealed by fermentation is 80h, described to be sealed by fermentation for the second time
Relative humidity be 75%.
Performance test 1:
Referring to " GB15979-2002 disposable sanitary articles sanitary standard " appendix C " product bactericidal property, bacteriostasis property with
Stability test method " antibiotic rate test is carried out to the Chinese medicine composition of embodiment 1-2 and comparative example 1-3, action time is 5 points
Clock.It the results are shown in Table 1.
Table 1
As shown in Table 1, the antibacterial effect in embodiment group is apparently higher than comparative example group, wherein although containing in comparative example 1
There are the tuber of pinellia and malt vinegar, but the two is only to be simply mixed, the not fermented ripe process of alcohol, acid solution and decomposition not yet in effect, effectively
Substance is not released, and antibacterial effect is bad.Although using the preparation process of fermenation raw liquid of the present invention in comparative example 3, partly
For the dosage of summer and malt vinegar not within the scope of proportion relation of the invention, antibacterial effect is poor, also illustrates fermenation raw liquid of the present invention
Formula is to grope to obtain through inventor's repetition test.
Performance test 2
Experimental design: moderate atopic dermatitis patient 4, wherein 1 patient smears the Chinese medicine composition in embodiment 1,
1 patient smears the Chinese medicine composition in embodiment 5, and 1 patient smears the Chinese medicine composition in embodiment 6, and 1 patient smears
Chinese medicine composition in comparative example 1.It is daily to smear Chinese medicine composition 3-5 times, it is continuous to smear 45 days.
As a result: the patient in embodiment 5, embodiment 6 cures, and erythema, swelling, papule, blister with it disappears.It smears
The patient symptom of the Chinese medicine composition of embodiment 1 is relieved, with it only a small amount of erythema, and the Chinese medicine group of comparative example 1
The patient symptom for closing object does not disappear, and still has erythema, swelling, the papule of large area with it.It is controlled to further verify the present invention
The therapeutic effect of the Chinese medicine composition of allergic dermatitis is treated, the patient for the Chinese medicine composition for smearing comparative example 1 is used again
Traditional Chinese medicine composition for treating in embodiment 5, it is daily to smear Chinese medicine composition 3-5 time, it is continuous to smear 40 days, it fully recovers, with it red
Spot, swelling, papule, blister disappear, and skin is without other allergic reactions.
Experimental design: pityriasis rosea patient 3, everyone respectively applies embodiment 9, embodiment 10 and comparative example 2 in the morning, afternoon and evening daily
In Chinese medicine composition, affected part warm water cleaning takes 75% concentration medicinal alcohol uniformly to smear affected part, 2 minutes alcohol waited to wave
After hair, then the Chinese medicine composition is taken to be evenly coated in affected part, is encased in affected part 20 minutes with preservative film.15 days courses for the treatment of, are controlled
Treat 2 courses for the treatment of.
As a result: the clinical symptoms performance for smearing two patients of embodiment 9, embodiment 10 is all eliminated, wound healing, purulence
Blister, erythema disappear, and skin starts self-healing, and follow-up 3 months do not recur, recovery from illness.Smear the Chinese medicine composition patient in comparative example 2
Though clinical symptoms have alleviation, wound does not heal, still there is warts, the erythema of larger area.Again to smearing in comparative example 2
The patient of Chinese medicine composition treated according to the above method using the Chinese medicine composition in embodiment 9, after 30 days, recovery from illness, wound is cured
Conjunction, warts, erythema disappear.
In addition, inventor also treats psoriasis, epifolliculitis and tinea pedis patient, wherein 10 psoriasis for the treatment of are suffered from
Person, fully recovers 5, invalid 0 by effective 5.9 epifolliculitis patients are treated, effective 5, are fully recovered 4, invalid 0.Treatment 8
Tinea pedis patient, fully recovers 6, invalid 0 by effective 2.It is pretherapy and post-treatment that Fig. 1 shows tinea pedis patient in one embodiment of the invention
Effect contrast figure；Fig. 2 shows the pretherapy and post-treatment effect contrast figures of psoriatic in one embodiment of the invention.
Other dermatosis patients also have obvious therapeutic effect, and therapeutic process is not repeating one by one herein.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (10)
1. a kind of preparation method of fermenation raw liquid, which is characterized in that the preparation method of the fermenation raw liquid includes the following steps:
The tuber of pinellia of 300-500 mass parts is taken to be ground into powdery, the wheat vinegar that 300-500 mass parts are added carries out first time sealing and fermenting
Half cooked food is obtained, under stirring, the wheat vinegar that 200-300 mass parts are added in half cooked food carries out second of sealing hair
Ferment is to get fermenation raw liquid.
2. the preparation method of fermenation raw liquid according to claim 1, which is characterized in that the temperature that the first time is sealed by fermentation
Degree is 15 DEG C -20 DEG C, and the time that the first time is sealed by fermentation is 160h-240h.
3. the preparation method of fermenation raw liquid according to claim 1, which is characterized in that second of temperature being sealed by fermentation
Degree is 20 DEG C -25 DEG C, and described second time being sealed by fermentation is 80h-100h.
4. the preparation method of fermenation raw liquid according to any one of claims 1 to 3, which is characterized in that described second close
The relative humidity of seal ferment is 75%-80%.
5. a kind of fermenation raw liquid, which is characterized in that be prepared using the described in any item preparation methods of Claims 1-4.
6. fermenation raw liquid described in claim 5 treats the application in dermopathic drug in preparation.
7. a kind of Chinese medicine composition for the treatment of venereal, which is characterized in that the raw material components of the Chinese medicine composition of the treating venereal
Including fermenation raw liquid described in claim 5, wheat vinegar, the rose of Sharon and julid, wherein the fermenation raw liquid is 100-200 mass parts, institute
State that wheat vinegar is 180-360 mass parts, the rose of Sharon is 30-50 mass parts, the julid is 25-50 mass parts.
8. a kind of Chinese medicine composition for treating allergic dermatitis, which is characterized in that the Chinese traditional medicine composition of the treatment allergic dermatitis
The raw material components of object include fermenation raw liquid described in claim 5, wheat vinegar and julid, wherein the fermenation raw liquid is 100-200 matter
Measure part, the wheat vinegar is 700-750 mass parts, the julid is 55-110 mass parts.
9. a kind of Chinese medicine composition for treating tinea pedis, which is characterized in that the raw material components of the Chinese medicine composition of the treatment tinea pedis
Including fermenation raw liquid described in claim 5, wheat vinegar, the rose of Sharon and rice vinegar, wherein the fermenation raw liquid is 100-200 mass parts, institute
State that wheat vinegar is 1600-1900 mass parts, the rose of Sharon is 25-50 mass parts, the rice vinegar is 100-200 mass parts.
10. a kind of Chinese medicine composition for treating pityriasis rosea, which is characterized in that the Chinese medicine composition of the treatment pityriasis rosea
Raw material components include fermenation raw liquid described in claim 5, wheat vinegar, the rose of Sharon and julid, wherein the fermenation raw liquid is 100-200
Mass parts, the wheat vinegar are 680-720 mass parts, the rose of Sharon is 100-150 mass parts, the julid is 10-15 mass parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811503557.1A CN109432255A (en) | 2018-12-10 | 2018-12-10 | Preparation method, fermenation raw liquid and the application of fermenation raw liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811503557.1A CN109432255A (en) | 2018-12-10 | 2018-12-10 | Preparation method, fermenation raw liquid and the application of fermenation raw liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109432255A true CN109432255A (en) | 2019-03-08 |
Family
ID=65557418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811503557.1A Pending CN109432255A (en) | 2018-12-10 | 2018-12-10 | Preparation method, fermenation raw liquid and the application of fermenation raw liquid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109432255A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857543A (en) * | 2006-03-27 | 2006-11-08 | 张新岭 | Externally applied Chinese medicine liniment for treating skin diseases |
| CN103356839A (en) * | 2013-07-19 | 2013-10-23 | 汤广银 | Chinese herbal compound preparation for treatment of skin diseases and its use method |
-
2018
- 2018-12-10 CN CN201811503557.1A patent/CN109432255A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857543A (en) * | 2006-03-27 | 2006-11-08 | 张新岭 | Externally applied Chinese medicine liniment for treating skin diseases |
| CN103356839A (en) * | 2013-07-19 | 2013-10-23 | 汤广银 | Chinese herbal compound preparation for treatment of skin diseases and its use method |
Non-Patent Citations (4)
| Title |
|---|
| 唐崇藏: "醋浸生半夏治疗手足癣 ", 《医学文选》 * |
| 夏传才: "《诗经学大辞典 下》", 31 March 2014, 河北教育出版社 * |
| 孙佳彬等: "发酵对半夏毒性和刺激性的影响", 《中药与临床》 * |
| 孙淑贞: "《科学原来如此 人类的神秘邻居》", 30 September 2013, 金盾出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107854367B (en) | Essence for repairing sensitive skin | |
| EP0279984B1 (en) | Pharmaceutical use of graminaceous extracts | |
| CN1939522A (en) | Externally-applied medicinal composition for treating dermatosis and its making method | |
| US7258876B2 (en) | Topical composition for treating infectious conditions of skin and mucosa | |
| CN109875940A (en) | A kind of preparation method and skin barrier reparation application of the Essence containing beta glucan | |
| CN101066285B (en) | Application of aweto preparation in preparing medicine for treating skin diseases | |
| CN107496792A (en) | A kind of gel of antiphlogistic antibacterial treatment onychomycosis and preparation method thereof | |
| CN1171259A (en) | Chinese medicine for curing burn and traumatic wound and its production method | |
| CN106620633A (en) | Skin repairing cream for tumor patients and preparation method of skin repairing cream | |
| KR20030055154A (en) | A composition for treating a dermatitis and a method of preparing the same | |
| CN109432255A (en) | Preparation method, fermenation raw liquid and the application of fermenation raw liquid | |
| CN1101856A (en) | Chinese medicine spray for curing burn and scald | |
| CN1084196C (en) | Burn ointment | |
| CN1524555A (en) | Exterior-applied Chinese herbal medicine preparation for traumatic infection and inflammation-relieving acesodyne and its preparation method | |
| CN1903222A (en) | Method and recipe for preparing cockroach band aid | |
| CN109200232A (en) | A kind of antipsoriatics object | |
| CN113368164B (en) | Anti-allergy traditional Chinese medicine formula leavening, preparation method and application thereof in cosmetics | |
| CN1060370C (en) | Medical ointment for treating arthritis and hyperosteogeny | |
| CN117815110B (en) | Moisturizing, soothing and whitening plant compound polysaccharide and preparation method and application thereof | |
| CN108785493B (en) | A composition for treating dermatoses, and its preparation method | |
| KR100915426B1 (en) | Functional cosmetics for improvement of atopic dermatitis using lotus and rice, and process for preparing the same | |
| CN116036149A (en) | Preparation method and application of nano-scale small molecular fruit nucleic acid ester composite antibacterial gel | |
| CN1177601C (en) | Medicine for treating scald | |
| CN104069056A (en) | Skin-soothing itching-relieving lotion | |
| CN118903358A (en) | Hemorrhoid treatment method containing ginger juice |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190308 |
|
| RJ01 | Rejection of invention patent application after publication |