CN109432137A - The preparation method of the prepared slices of Chinese crude drugs - Google Patents
The preparation method of the prepared slices of Chinese crude drugs Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A61K2236/10—Preparation or pretreatment of starting material
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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Abstract
The invention discloses a kind of preparation methods of prepared slices of Chinese crude drugs, comprising steps of by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；Cleaning treated Chinese medicine is subjected to sofening treatment, is transferred in sterile shady and cool library and stands immediately after Chinese medicine softening, thinly sliced later using slicer；Thin slice after slice is dried by circulating baking oven, obtains the prepared slices of Chinese crude drugs.The present invention carries out cleaning processing to Chinese medicine by using water catalyst technology and, to improve the demulcen bating effect in prepared slices of Chinese crude drugs process, sterilization rate and effective component storage rate, improves the quality of the prepared slices of Chinese crude drugs in combination with sofening treatment etc..
Description
Technical field
The present invention relates to drug preparation technique fields, and in particular to a kind of preparation method of the prepared slices of Chinese crude drugs.
Background technique
The prepared slices of Chinese crude drugs be traditional Chinese medicine basic theory guidance under, by Chinese medicine by clean, cutting and process three big processes,
The finished product of certain specification is made.In existing processing method, after selecting, often medicinal material is not cleaned, is substantially reduced
The cleanliness of medicinal material；Giant is such as only used using conventional method cleaning, to remove soil on medicinal material etc., still
Cleanliness is not high.When cutting, medicine materical crude slice is uneven, thickness, length, and granularity difference is too big.Just it will appear during decocting for Chinese herbal medicine
Medicinal ingredient dissolution is different, influences drug effect；If desired further heating processes, and there is also uneven heating, raw ripe different, drug effect
There is different situation, therefore, cutting is extremely important to the quality of the prepared slices of Chinese crude drugs.Currently, sofening treatment method of the medicinal material before cutting
Mainly have: no matter leaching method, elutriation method, bubble method, drift method, profit method, vacuum heating tenderizer and decompression cold soaking tenderizer etc. select which
Kind method will adhere to the more profits of few bubble, the permeable most principle of medicine.If excessive, long soaking time normally results in medicine with water
Material hurts water, and the ingredient in medicinal material is largely lost, and lessens the curative effect, and next difficult to the dry zone of medicine materical crude slice, is also easy to discoloration length occur
It is mould.For defect present in existing method, it is necessary for developing the novel prepared slices of Chinese crude drugs processing method of one kind.
Summary of the invention
For the defects in the prior art, the present invention provides a kind of preparation method of prepared slices of Chinese crude drugs, to touch by using water
Matchmaker's technology carries out cleaning processing to Chinese medicine, in combination with sofening treatment etc., to improve in prepared slices of Chinese crude drugs process
Demulcen bating effect, sterilization rate and effective component storage rate, improve the quality of the prepared slices of Chinese crude drugs.
To achieve the above object, technical solution provided by the invention are as follows:
The present invention provides a kind of preparation methods of prepared slices of Chinese crude drugs, comprising steps of by Chinese medicine by manually or mechanically into
The part that row screening, removal impurity and separation cannot be used as medicine；Chinese medicine after screening is cleaned using water catalytic control machine
Purified treatment；Cleaning treated Chinese medicine is subjected to sofening treatment, is transferred to sterile cool place immediately after Chinese medicine softening
It stands in library, is thinly sliced later using slicer；Thin slice after slice is dried by circulating baking oven, obtains Chinese medicine
Medicine materical crude slice.
Preferably, in the preparation method of the prepared slices of Chinese crude drugs, dry temperature is 55~60 DEG C；Dry pressure be 0.1~
0.2Mpa；The water content of medicinal material after drying is not higher than 15%.
Preferably, in the preparation method of the prepared slices of Chinese crude drugs, sofening treatment specifically includes step: by cleaning during treated
Medicinal material is put into steamer, pressurization plus water, 8~12min of Steam by water bath.
Preferably, in the preparation method of the prepared slices of Chinese crude drugs, sofening treatment specifically includes step: by cleaning during treated
Medicinal material is put into closed container, is passed through the vapor that temperature is lower than 60 DEG C, is saturated vapor in closed container sufficiently, passes through increasing
Press pump makes interior pressure be higher than 3~4 times of atmospheric pressure to vapor pressurization is passed through, it is closed after ultrasonic frequency control 20~
30KHz ultrasound.
It is further preferred that the closed rear ultrasonic time of rhizome traditional Chinese medicinal materials is greater than the closed rear ultrasound of caulis Chinese medicine
Time；The closed rear ultrasonic time of caulis Chinese medicine is greater than the closed rear ultrasonic time of traditional Chinese medicinal herbs from entire grass.
It is further preferred that rhizome traditional Chinese medicinal materials it is closed after ultrasonic time be 60~90min, caulis Chinese medicine it is close
Closing rear ultrasonic time is 20~30min, and the closed rear ultrasonic time of traditional Chinese medicinal herbs from entire grass is 15~18min.
It preferably, further include removing heavy metals and chemical fertilizer, pesticide residue before dry in the preparation method of the prepared slices of Chinese crude drugs
The step of, it specifically includes step: the thin slice after slice is cleaned by bathing preparation, embathing the time is 10~15min；Its
In, bathing preparation is ethanol water；The volume fraction of ethanol water is 30%~45%.
Preferably, in the preparation method of the prepared slices of Chinese crude drugs, the gas in sterile cool place library includes: oxygen, carbon dioxide, nitrogen
And ozone；Wherein, the volume ratio of oxygen, carbon dioxide, nitrogen and ozone is 1:(0.4~0.6): (2.0~2.6): (0.2~
0.4)；The total concentration of all gas is 0.5~0.6 μ L/L.
Preferably, in the preparation method of the prepared slices of Chinese crude drugs, the temperature in sterile cool place library is 26~28 DEG C, and relative humidity is
12%~18%.
The preparation method of the prepared slices of Chinese crude drugs provided by the invention, Chinese medicine may include tubers, caulis, whole grass etc.,
Including but not limited to dandelion, rhizome of cyrtomium, smelly Changshan, cape jasmine, Herba Andrographitis, cortex moutan, oriental wormwood, caulis akebiae, the shell of areca nut, lepidium seed, mulberry
Branch, the tuber of multiflower knotweed, reed root, Longstamen Onion Bulb, ginseng, hairyvein agrimony, barberry, caulis lonicerae, wild chrysanthemum, radix paeoniae rubra, fuling peel, pueraria lobata, Radix Paeoniae Alba, Huang
Essence, Radix Salviae Miltiorrhizae, radix bupleuri, wild chrysanthemum, folium isatidis, tribulus terrestris, Radix Astragali, tobacco, azedarach, white portion, cortex dictamni, kuh-seng, radix saposhnikoviae, wormwood artemisia
Sheet, the root of Dahurain angelica, Cassia occidentalis, salvia chinensis, fructus viticis, gleditsia sinensis, radix ampelopsis, Rhizoma Gastrodiae, the root bark of white mulberry, the root of gansui, hypericum japonicum, radix aucklandiae, Rhizoma Chuanxiong, Radix Angelicae Sinensis,
Blackberry lily, Asian puccoon, the leaf of bamboo, field pennycress, Centipeda minima, Herba Ecliptae, pipewort, the seed of feather cockscomb, radix pseudostellariae, edible tulip, the bletilla striata, uncaria,
West safflower, dendrobium nobile, cordate houttuynia, saddle grass, aleppo avens, Verbena officinalis, Chinese gall, peppermint, Radix zanthoxyli, Equisetum hiemale Linne, radix scrophulariae, Niu Xi,
Schizonepeta, HERBA HEDYOTIS DIFFUSAE, lobelia chinensis, frutus cnidii, rhizoma cyperi, corydalis tuber, caulis bambusae in taenian, Wikstroemia indica, Radix Notoginseng, safflower, ramulus cinnamomi, dried orange peel, semen coicis, party
One of ginseng, Caulis Perillae, oldenlandia diffusa, dandelion, lily, fingered citron, Poria cocos, Radix Glycyrrhizae are a variety of.It should be noted that this
The preparation method provided is provided, can be also used for the processing preparation of the agricultural product such as tealeaves.
Technical solution provided by the invention, with following the utility model has the advantages that the preparation of (1) prepared slices of Chinese crude drugs provided by the invention
Method carries out cleaning processing to Chinese medicine by using water catalyst technology, in combination with sofening treatment etc., thus in improving
Demulcen bating effect, sterilization rate and effective component storage rate in medicine medicine materical crude slice process, improve the quality of the prepared slices of Chinese crude drugs；(2)
The preparation method of the prepared slices of Chinese crude drugs provided by the invention can be improved the Storing quality of the prepared slices of Chinese crude drugs, extend the shelf life, and reduce micro- life
The hyperplasia of object avoids the destruction of effective component, provides scientific and effective method for the preservation of the prepared slices of Chinese crude drugs；(3) present invention mentions
The preparation method of the prepared slices of Chinese crude drugs of confession is simple, low in cost, extensive using type, has a good application prospect.
Additional aspect and advantage of the invention will be set forth in part in the description, and will partially become from the following description
Obviously, or practice through the invention is recognized.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical solution of the present invention is clearly and completely described.Implement below
Example is only used for clearly illustrating technical solution of the present invention, therefore is intended only as example, and cannot be used as a limitation and limit this hair
Bright protection scope.
Experimental method in following embodiments is unless otherwise specified conventional method.Examination as used in the following examples
Material is tested, is to be commercially available from regular shops unless otherwise specified.Quantitative test in following embodiment, is respectively provided with three
Secondary to repeat to test, data are the average value or mean+SD of three repeated experiments.
The present invention provides a kind of preparation method of prepared slices of Chinese crude drugs, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；
Wherein, sofening treatment specifically includes step: by cleaning, treated that Chinese medicine is put into steamer, pressurization,
Add water, 8~12min of Steam by water bath；Alternatively, sofening treatment specifically includes step: by cleaning, treated that Chinese medicine is put into is close
It closes in container, is passed through temperature and is lower than 60 DEG C of vapor, be saturated vapor in closed container sufficiently, by booster pump to being passed through
Vapor pressurization makes interior pressure higher than 3~4 times of atmospheric pressure, and closed rear ultrasonic frequency control is in 20~30KHz ultrasound；Root
Stem class Chinese medicine it is closed after ultrasonic time be 60~90min, caulis Chinese medicine it is closed after ultrasonic time be 20~
The closed rear ultrasonic time of 30min, traditional Chinese medicinal herbs from entire grass are 15~18min；
Temperature in sterile cool place library is 26~28 DEG C, and relative humidity is 12%~18%, the gas in sterile cool place library
It is 1:(0.4~0.6 including volume ratio): (2.0~2.6): oxygen, carbon dioxide, nitrogen and the ozone of (0.2~0.4) own
The total concentration of gas is 0.5~0.6 μ L/L；
S4: the thin slice after slice is dried by circulating baking oven, is obtained Chinese medicine of the water content not higher than 15% and is drunk
Piece；Wherein, dry temperature is 55~60 DEG C；Dry pressure is 0.1~0.2Mpa.
It further include removing heavy metals and chemical fertilizer, pesticide residue before dry in further embodiment of the invention
Step specifically includes step: the thin slice after slice being cleaned by bathing preparation, embathing the time is 10~15min；Wherein,
Bathing preparation is the ethanol water that volume fraction is 30%~45%.
The preparation method of the prepared slices of Chinese crude drugs provided by the invention is described further combined with specific embodiments below.
Embodiment 1
The present embodiment provides a kind of preparation methods of prepared slices of Chinese crude drugs rhizoma polygonati, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；Wherein, sofening treatment specifically includes step: after cleaning is handled
Chinese medicine be put into steamer, pressurization, plus water, Steam by water bath 10min；
S4: it will be dried by the thin slice of S3 processing by circulating baking oven, and obtain water content and be not higher than in 15%
Medicine medicine materical crude slice；Wherein, dry temperature is 58 DEG C；Dry pressure is 0.15Mpa.
Embodiment 2
The present embodiment provides a kind of preparation methods of prepared slices of Chinese crude drugs rhizoma polygonati, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；Wherein, sofening treatment specifically includes step: after cleaning is handled
Chinese medicine be put into steamer, pressurization, plus water, Steam by water bath 10min；Temperature in sterile cool place library is 27 DEG C, relative humidity
It is 15%, the gas in sterile cool place library includes oxygen, carbon dioxide, nitrogen and the ozone that volume ratio is 1:0.5:2.3:0.3,
The total concentration of all gas is 0.54 μ L/L；
S4: it will be dried by the thin slice of S3 processing by circulating baking oven, and obtain water content and be not higher than in 15%
Medicine medicine materical crude slice；Wherein, dry temperature is 58 DEG C；Dry pressure is 0.15Mpa.
Embodiment 3
The present embodiment provides a kind of preparation methods of prepared slices of Chinese crude drugs rhizoma polygonati, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；Wherein, sofening treatment specifically includes step: after cleaning is handled
Chinese medicine be put into steamer, pressurization, plus water, Steam by water bath 10min；Temperature in sterile cool place library is 27 DEG C, relative humidity
It is 15%, the gas in sterile cool place library includes oxygen, carbon dioxide, nitrogen and the ozone that volume ratio is 1:0.5:2.3:0.3,
The total concentration of all gas is 0.54 μ L/L；
S4: the thin slice after slice is cleaned by bathing preparation ethanol water, and embathing the time is 12min, with removal
Heavy metal and chemical fertilizer, pesticide residue；Wherein, the volume fraction of ethanol water is 35%；
S5: it will be dried by the thin slice of S4 processing by circulating baking oven, and obtain water content and be not higher than in 15%
Medicine medicine materical crude slice；Wherein, dry temperature is 58 DEG C；Dry pressure is 0.15Mpa.
Embodiment 4
The present embodiment provides a kind of preparation methods of prepared slices of Chinese crude drugs rhizoma polygonati, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；Wherein, sofening treatment specifically includes step: after cleaning is handled
Chinese medicine be put into closed container, be passed through temperature and be lower than 60 DEG C of vapor, be saturated vapor in closed container sufficiently, lead to
Booster pump is crossed to vapor pressurization is passed through, makes interior pressure higher than 3.5 times of atmospheric pressure, closed rear ultrasonic frequency control exists
25KHz ultrasound 75min；Temperature in sterile cool place library is 27 DEG C, relative humidity 15%, and the gas in sterile cool place library includes
Volume ratio is oxygen, carbon dioxide, nitrogen and the ozone of 1:0.5:2.3:0.3, and the total concentration of all gas is 0.54 μ L/L；
S4: the thin slice after slice is cleaned by bathing preparation ethanol water, and embathing the time is 12min, with removal
Heavy metal and chemical fertilizer, pesticide residue；Wherein, the volume fraction of ethanol water is 35%；
S5: it will be dried by the thin slice of S4 processing by circulating baking oven, and obtain water content and be not higher than in 15%
Medicine medicine materical crude slice；Wherein, dry temperature is 58 DEG C；Dry pressure is 0.15Mpa.
Embodiment 5
The present embodiment provides a kind of preparation methods of prepared slices of Chinese crude drugs rhizoma polygonati, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；Wherein, sofening treatment specifically includes step: after cleaning is handled
Chinese medicine be put into closed container, be passed through temperature and be lower than 60 DEG C of vapor, be saturated vapor in closed container sufficiently, lead to
Booster pump is crossed to vapor pressurization is passed through, makes interior pressure higher than 3 times of atmospheric pressure, closed rear ultrasonic frequency control is in 20KHz
Ultrasonic 60min；Temperature in sterile cool place library is 26 DEG C, relative humidity 12%, and the gas in sterile cool place library includes volume
Than being 0.5 μ L/L for the total concentration of the oxygen of 1:0.4:2.0:0.2, carbon dioxide, nitrogen and ozone, all gas；
S4: the thin slice after slice is cleaned by bathing preparation ethanol water, and embathing the time is 10min, with removal
Heavy metal and chemical fertilizer, pesticide residue；Wherein, the volume fraction of ethanol water is 30%；
S5: it will be dried by the thin slice of S4 processing by circulating baking oven, and obtain water content and be not higher than in 15%
Medicine medicine materical crude slice；Wherein, dry temperature is 55 DEG C；Dry pressure is 0.1Mpa.
Comparative example 1
This comparative example provides a kind of preparation method of prepared slices of Chinese crude drugs rhizoma polygonati, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；
Wherein, sofening treatment specifically includes step: by cleaning, treated that Chinese medicine is put into closed container, is passed through
Temperature is lower than 60 DEG C of vapor, is saturated vapor in closed container sufficiently, by booster pump to vapor pressurization is passed through, makes
Interior pressure is higher than 3.5 times of atmospheric pressure, and closed rear ultrasonic frequency control is in 25KHz ultrasound 75min；Temperature in sterile cool place library
Degree is 27 DEG C, relative humidity 15%, and it is the oxygen of 1:0.5:2.3, titanium dioxide that the gas in sterile cool place library, which includes volume ratio,
Carbon, nitrogen, the total concentration of all gas are 0.54 μ L/L；
S4: the thin slice after slice is cleaned by bathing preparation ethanol water, and embathing the time is 12min, with removal
Heavy metal and chemical fertilizer, pesticide residue；Wherein, the volume fraction of ethanol water is 35%；
S5: it will be dried by the thin slice of S4 processing by circulating baking oven, and obtain water content and be not higher than in 15%
Medicine medicine materical crude slice；Wherein, dry temperature is 58 DEG C；Dry pressure is 0.15Mpa.
Comparative example 2
This comparative example provides a kind of preparation method of prepared slices of Chinese crude drugs rhizoma polygonati, comprising steps of
S1: by Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
S2: the Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
S3: carrying out sofening treatment for cleaning treated Chinese medicine, is transferred to sterile yin immediately after Chinese medicine softening
It stands in cool library, is thinly sliced later using slicer；
Wherein, sofening treatment specifically includes step: by cleaning, treated that Chinese medicine is put into closed container, is passed through
Temperature is lower than 60 DEG C of vapor, is saturated vapor in closed container sufficiently, and closed rear ultrasonic frequency control is super in 25KHz
Sound 75min；Temperature in sterile cool place library is 27 DEG C, relative humidity 15%, and the gas in sterile cool place library includes volume ratio
For the oxygen of 1:0.5:2.3:0.3, carbon dioxide, nitrogen and ozone, the total concentration of all gas is 0.54 μ L/L；
S4: the thin slice after slice is cleaned by bathing preparation ethanol water, and embathing the time is 12min, with removal
Heavy metal and chemical fertilizer, pesticide residue；Wherein, the volume fraction of ethanol water is 35%；
S5: it will be dried by the thin slice of S4 processing by circulating baking oven, and obtain water content and be not higher than in 15%
Medicine medicine materical crude slice；Wherein, dry temperature is 58 DEG C；Dry pressure is 0.15Mpa.
The prepared slices of Chinese crude drugs that the embodiment of the present invention 1 to embodiment 5, comparative example 1 and comparative example 2 are prepared imitate softening
Fruit, sterilization rate, residual quantity of heavy metal and effective component storage rate are evaluated.
Bating effect, sterilization rate and effective component storage rate result are as shown in table 1 below.In the evaluation of bating effect, 1 is nothing
Bating effect, 5 is best (no breakage) for bating effect；Residual quantity of heavy metal is with the residual quantity of heavy metal in embodiment 1
100%；Effective component is with respect to storage rate with the effective component storage rate in embodiment 1 for 100%.
1 bating effect of table, sterilization rate and effective component are with respect to storage rate result
It should be noted that unless otherwise indicated, technical term or scientific term used in this application should be this hair
The ordinary meaning that bright one of ordinary skill in the art are understood.Unless specifically stated otherwise, it otherwise illustrates in these embodiments
Component and opposite step, numerical expression and the numerical value of step are not limit the scope of the invention.It is illustrated and described herein
In all examples, unless otherwise prescribed, any occurrence should be construed as merely illustratively, not as limitation, because
This, other examples of exemplary embodiment can have different values.
In the description of the present invention, it is to be understood that, term " first ", " second " are used for description purposes only, and cannot
It is interpreted as indication or suggestion relative importance or implicitly indicates the quantity of indicated technical characteristic.Define as a result, " the
One ", the feature of " second " can explicitly or implicitly include one or more of the features.In the description of the present invention,
The meaning of " plurality " is two or more, unless otherwise specifically defined.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme should all cover within the scope of the claims and the description of the invention.
Claims (10)
1. a kind of preparation method of the prepared slices of Chinese crude drugs, which is characterized in that comprising steps of
By Chinese medicine by manually or mechanically sieving, removing impurity and separating the part that cannot be used as medicine；
Chinese medicine after screening is subjected to cleaning processing using water catalytic control machine；
Cleaning treated Chinese medicine is subjected to sofening treatment, is transferred to immediately after Chinese medicine softening quiet in sterile shady and cool library
It sets, is thinly sliced later using slicer；
Thin slice after slice is dried by circulating baking oven, obtains the prepared slices of Chinese crude drugs.
2. the preparation method of the prepared slices of Chinese crude drugs according to claim 1, it is characterised in that:
The temperature of the drying is 55~60 DEG C；
The pressure of the drying is 0.1~0.2Mpa；
The water content of medicinal material after drying is not higher than 15%.
3. the preparation method of the prepared slices of Chinese crude drugs according to claim 1, it is characterised in that:
The sofening treatment specifically includes step: by cleaning, treated that Chinese medicine is put into steamer, pressurization plus water,
8~12min of Steam by water bath.
4. the preparation method of the prepared slices of Chinese crude drugs according to claim 1, it is characterised in that:
The sofening treatment specifically includes step: by cleaning, treated that Chinese medicine is put into closed container, is passed through temperature
Vapor lower than 60 DEG C is saturated vapor in closed container sufficiently, by booster pump to vapor pressurization is passed through, makes internal pressure
Power is higher than 3~4 times of atmospheric pressure, and closed rear ultrasonic frequency control is in 20~30KHz ultrasound.
5. the preparation method of the prepared slices of Chinese crude drugs according to claim 4, it is characterised in that:
The closed rear ultrasonic time of rhizome traditional Chinese medicinal materials is greater than the closed rear ultrasonic time of caulis Chinese medicine；
The closed rear ultrasonic time of caulis Chinese medicine is greater than the closed rear ultrasonic time of traditional Chinese medicinal herbs from entire grass.
6. the preparation method of the prepared slices of Chinese crude drugs according to claim 5, it is characterised in that:
The closed rear ultrasonic time of the rhizome traditional Chinese medicinal materials is 60~90min, the closed rear ultrasound of the caulis Chinese medicine
Time is 20~30min, and the closed rear ultrasonic time of the traditional Chinese medicinal herbs from entire grass is 15~18min.
7. the preparation method of the prepared slices of Chinese crude drugs according to claim 1, it is characterised in that:
Before the drying, further includes the steps that removing heavy metals and chemical fertilizer, pesticide residue, specifically include step: after slice
Thin slice cleaned by bathing preparation, embathe the time be 10~15min；
Wherein, the bathing preparation is ethanol water；The volume fraction of the ethanol water is 30%~45%.
8. the preparation method of the prepared slices of Chinese crude drugs according to claim 1, it is characterised in that:
Gas in the sterile shady and cool library includes: oxygen, carbon dioxide, nitrogen and ozone；
Wherein, the volume ratio of the oxygen, the carbon dioxide, the nitrogen and the ozone is 1:(0.4~0.6): (2.0
~2.6): (0.2~0.4)；The total concentration of all gas is 0.5~0.6 μ L/L.
9. the preparation method of the prepared slices of Chinese crude drugs according to claim 1, it is characterised in that:
Temperature in the sterile shady and cool library is 26~28 DEG C, and relative humidity is 12%~18%.
10. the preparation method of -9 described in any item prepared slices of Chinese crude drugs according to claim 1, it is characterised in that:
The Chinese medicine includes but is not limited to dandelion, rhizome of cyrtomium, smelly Changshan, cape jasmine, Herba Andrographitis, cortex moutan, oriental wormwood, caulis akebiae, big
Abdomen skin, lepidium seed, ramulus mori, the tuber of multiflower knotweed, reed root, Longstamen Onion Bulb, ginseng, hairyvein agrimony, barberry, caulis lonicerae, wild chrysanthemum, radix paeoniae rubra, fuling peel,
Pueraria lobata, Radix Paeoniae Alba, rhizoma polygonati, Radix Salviae Miltiorrhizae, radix bupleuri, wild chrysanthemum, folium isatidis, tribulus terrestris, Radix Astragali, tobacco, azedarach, white portion, cortex dictamni, hardship
Ginseng, radix saposhnikoviae, ligusticum sinense oliver, the root of Dahurain angelica, Cassia occidentalis, salvia chinensis, fructus viticis, gleditsia sinensis, radix ampelopsis, Rhizoma Gastrodiae, the root bark of white mulberry, the root of gansui, hypericum japonicum, radix aucklandiae,
Rhizoma Chuanxiong, Radix Angelicae Sinensis, blackberry lily, Asian puccoon, the leaf of bamboo, field pennycress, Centipeda minima, Herba Ecliptae, pipewort, the seed of feather cockscomb, radix pseudostellariae, edible tulip,
The bletilla striata, uncaria, west safflower, dendrobium nobile, cordate houttuynia, saddle grass, aleppo avens, Verbena officinalis, Chinese gall, peppermint, Radix zanthoxyli, Equisetum hiemale Linne,
It is radix scrophulariae, Niu Xi, schizonepeta, HERBA HEDYOTIS DIFFUSAE, lobelia chinensis, frutus cnidii, rhizoma cyperi, corydalis tuber, caulis bambusae in taenian, Wikstroemia indica, Radix Notoginseng, safflower, ramulus cinnamomi, old
One of skin, semen coicis, Radix Codonopsis, Caulis Perillae, oldenlandia diffusa, dandelion, lily, fingered citron, Poria cocos, Radix Glycyrrhizae are a variety of.
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| CN109966257A (en) * | 2019-04-24 | 2019-07-05 | 安徽济顺中药饮片有限公司 | A kind of processing method of the prepared slices of Chinese crude drugs |
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