CN109401858A - A kind of medical instrument solid cleaner and preparation method thereof - Google Patents

A kind of medical instrument solid cleaner and preparation method thereof Download PDF

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Publication number
CN109401858A
CN109401858A CN201811213747.XA CN201811213747A CN109401858A CN 109401858 A CN109401858 A CN 109401858A CN 201811213747 A CN201811213747 A CN 201811213747A CN 109401858 A CN109401858 A CN 109401858A
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CN
China
Prior art keywords
solid
cleaner
chamber
medical instrument
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811213747.XA
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Chinese (zh)
Inventor
王卫
施君君
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Jusha Display Technology Co Ltd
Nanjing Jusha Medical Technology Co Ltd
Nanjing Jusha Commercial and Trading Co Ltd
Original Assignee
Nanjing Jusha Display Technology Co Ltd
Nanjing Jusha Medical Technology Co Ltd
Nanjing Jusha Commercial and Trading Co Ltd
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Filing date
Publication date
Application filed by Nanjing Jusha Display Technology Co Ltd, Nanjing Jusha Medical Technology Co Ltd, Nanjing Jusha Commercial and Trading Co Ltd filed Critical Nanjing Jusha Display Technology Co Ltd
Priority to CN201811213747.XA priority Critical patent/CN109401858A/en
Publication of CN109401858A publication Critical patent/CN109401858A/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/72—Ethers of polyoxyalkylene glycols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0034—Fixed on a solid conventional detergent ingredient
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
    • C11D17/041—Compositions releasably affixed on a substrate or incorporated into a dispensing means
    • C11D17/042—Water soluble or water disintegrable containers or substrates containing cleaning compositions or additives for cleaning compositions
    • C11D17/045—Multi-compartment
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/34—Organic compounds containing sulfur
    • C11D3/349—Organic compounds containing sulfur additionally containing nitrogen atoms, e.g. nitro, nitroso, amino, imino, nitrilo, nitrile groups containing compounds or their derivatives or thio urea
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers
    • C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3707—Polyethers, e.g. polyalkyleneoxides
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/02—Inorganic compounds
    • C11D7/04—Water-soluble compounds
    • C11D7/06—Hydroxides
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/02—Inorganic compounds
    • C11D7/04—Water-soluble compounds
    • C11D7/10—Salts
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/02—Inorganic compounds
    • C11D7/04—Water-soluble compounds
    • C11D7/10—Salts
    • C11D7/12—Carbonates bicarbonates
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/02—Inorganic compounds
    • C11D7/04—Water-soluble compounds
    • C11D7/10—Salts
    • C11D7/14—Silicates
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/26—Organic compounds containing oxygen
    • C11D7/265—Carboxylic acids or salts thereof
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/40—Products in which the composition is not well defined

Abstract

The invention discloses a kind of medical instrument solid cleaners and preparation method thereof, the solid cleaner includes the solid matrix of stereochemical structure, two independent accommodating cavities are provided in the inside of the solid matrix, are respectively intended to place the second chamber of the first chamber and solid union enzyme of sealing package liquid cleaner up for safekeeping.Aqueous cleaning liquid and solid union enzyme are sealed by using water-soluble film, two accommodating cavities for being put into solid matrix later are prepared.Prepared solid cleaner can thoroughly clean surgical instrument surface contaminants by synergistic effect, while enzyme and other materials are separated, and higher activity can be always held at by also further ensuring enzyme activity in cleaning agent.And present invention solid cleaner produced also have it is small in size, it is light-weight, it is easy to use, be easy to the advantages that saving.

Description

A kind of medical instrument solid cleaner and preparation method thereof
Technical field
The invention belongs to medical fields, and in particular to a kind of medical instrument solid cleaner and preparation method thereof.
Background technique
Hospital's prevention and control infection need to clean the quasi- stringent process of surgical instrument sighting target, this is medical instrument The most important link sterilized before sterilizing and in reprocessing.Cleaning surgical instrument needs are carried out in strict accordance with process, and operating procedure is It rinses, washs, rinsing, the secondary rinsing of pure water lubricates the processes such as dry, and many surgical instruments need to carry out hand before being cleaned Work prerinse or ultrasonic cleaning first remove the visible bulk dirt of naked eyes.In order to guarantee Disinfection Effect, disinfection and supply center at present It needs scene to configure in proportion when the cleaning used, increases the workload of medical staff.With universal, the cleaning of specification cleaning Agent one is changed with one increasingly becomes normality, it is therefore desirable to configure a kind of formula of quickly and effectively cleaning agent.Storage current simultaneously The organized enzyme in cleaning agent is stored in the environment of liquid, over time, enzyme activity can a sharp decline until Initial 70~80% or so, cause cleaning force to decline, therefore the effective activity for guaranteeing enzyme in cleaning agent is also medical cleaning Industry institute problem to be solved.
Summary of the invention
In view of the above-mentioned problems, the present invention proposes a kind of medical instrument solid cleaner and preparation method thereof.
It realizes above-mentioned technical purpose, reaches above-mentioned technical effect, the invention is realized by the following technical scheme:
A kind of medical instrument solid cleaner, the solid matrix including stereochemical structure, in the inside of the solid matrix Provided with two independent accommodating cavities, it is respectively intended to place the first chamber and solid union enzyme for sealing package liquid cleaner up for safekeeping Second chamber.
As a further improvement of the present invention, using water-soluble film by the liquid cleaner or solid union enzyme into Row, which is sealed up for safekeeping, to be placed in first chamber or second chamber.
As a further improvement of the present invention, the liquid cleaner includes following components by mass percentage: 5%~ 30% polyoxyethylene ether, 1~5% decontamination synergist, 1%~10% antirust agent, 1%~3% fungicide, 1%~ 3% chelating agent, 0.1%~0.5% water and a small amount of solvent.
As a further improvement of the present invention, the molecular structural formula of the polyoxyalkyl ether is R- (OC2H4)x– (OC3H6)Y-OH；Wherein, R indicates C8-C18Line style or branched-alkyl, the number that the number of X is selected from 3~20, Y is selected from 0~ 15。
As a further improvement of the present invention, the chelating agent is sodium tripolyphosphate, four sodium of glutamic acid diacetic acid, methyl Glycine oxalic acid trisodium salt and the one or several kinds of mixtures of α-sodium glucoheptonate.
As a further improvement of the present invention, the fungicide non-formaldehyde discharges class fungicide, the different thiophene of chloro- 2 methyl -4 of 5- One of -3 ketone of oxazoline, 2-methyl-4-isothiazolin-3-one, 1,2- benzisothiazole-3-ketone or several mixtures.
As a further improvement of the present invention, the solid union enzyme includes protease, amylase, cellulase and rouge Two or more mixture in fat enzyme.
As a further improvement of the present invention, the solid matrix includes following components by mass percentage:
Prepare a kind of above-described medical instrument solid cleaner, comprising the following steps:
Seal liquid cleaner up for safekeeping: by polyoxyethylene ether, decontamination synergist, antirust agent, fungicide, chelating agent, water and solvent It is mixed evenly in a stirring kettle and mixed liquid is made, liquid is transferred in the mold A on the first molding machine later, is adopted Aqueous cleaning liquid is sealed with water-soluble film；
It seals solid union enzyme up for safekeeping: in the mold B on the second molding machine, a variety of biological enzyme will be mixed using water-soluble film Powder is sealed；
Prepare solid cleaner:
3-1: solid matrix is prepared: by NaOH, Na2CO3, sodium metasilicate, sodium sulphate, sodium citrate, paraffin, polyethylene glycol Be put into stirred tank with water by allocation ratio, 50~60 DEG C at a temperature of be uniformly mixed；Mixed liquor is put into later being capable of shape At being cooled down in the mold C of first chamber and second chamber；
3-2: it when mixed liquor cooling in mold C is in paste, is respectively put into and seals up for safekeeping in first chamber and second chamber Liquid cleaner and solid union enzyme, later in the mixed liquor of mold C Surface covering solid matrix until cooling.
Beneficial effects of the present invention: solid cleaner prepared by the present invention passes through the effective component liquid of cleaning agent is clear Lotion and solid union enzyme is independent is sealed in water-soluble solid matrix, can allow these substances to pass through successively different Dissolution sequence plays each self-applying.Cleaning agent substrate in solid matrix first washes off grease, the bloodstain of bulk, after then passing through Continuous surfactant and multienzyme cleans up the substances such as the biomembrane being difficult to clean off.By the synergistic effect of these substances, Thoroughly cleaning surgical instrument surface contaminants.Enzyme and other materials are separated simultaneously, also further ensure enzyme activity in cleaning agent Higher activity can be always held at.And present invention solid cleaner produced also has small in size, light-weight, user Just, it is easy to the advantages that saving.
Detailed description of the invention
Fig. 1 is the diagrammatic cross-section of present invention solid cleaner produced.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Application principle of the invention is explained in detail with reference to the accompanying drawing.
Medical instrument solid cleaner as described in Figure 1, the solid matrix 3 including stereochemical structure, in the solid-state base The inside of body 3 is provided with two independent accommodating cavities, is respectively intended to place 1 He of first chamber for sealing package liquid cleaner up for safekeeping The second chamber 2 of solid union enzyme.Wherein, the liquid cleaner or solid union enzyme are sealed using water-soluble film It deposits, and is placed in first chamber 1 or second chamber 2.
Specific preparation process is as follows:
(1) liquid cleaner is sealed up for safekeeping: by polyoxyalkyl ether, decontamination synergist, antirust agent, fungicide, chelating agent, water and molten Agent is mixed evenly in a stirring kettle is made mixed liquid, and liquid is transferred in the mold A on the first molding machine later, is adopted Aqueous cleaning liquid is sealed with water-soluble film；
(2) it seals solid union enzyme up for safekeeping: in the mold B on the second molding machine, a variety of lifes will be mixed using water-soluble film Object enzyme powder is sealed；
(3) solid cleaner is prepared:
3-1: prepare solid matrix 3: by alkali, soda ash, sodium metasilicate, sodium sulphate, sodium citrate, paraffin, polyethylene glycol and Water is put into stirred tank by allocation ratio, 50~60 DEG C at a temperature of be uniformly mixed；Mixed liquor is put into later and is capable of forming It is cooled down in the mold C of first chamber 1 and second chamber 2；
3-2: when mixed liquor cooling in mold C is in paste, envelope is respectively put into first chamber 1 and second chamber 2 The liquid cleaner and solid union enzyme deposited, later in the mixed liquor of mold C Surface covering solid matrix 3 until cooling.
In preparation process, used first molding machine and the second molding machine are fuse machine, the mold A and mold B The shape with first chamber 1 and second chamber 2 matches respectively, and the two is put into the heating mantle of fuse machine, water-soluble film It is close to the inner wall of mold A and mold B.The size of the volume of described in the present invention first chamber 1 and second chamber 2 with sealed The content of the liquid cleaner and solid union enzyme deposited is consistent.
Used mold C be include mold that dismountable upper-lower casing is formed by inner hollow, using constant displacement pump Will be in the hollow spaces inside the mixed liquor press-in die C that solid matrix 3 be prepared, being formed has first chamber 1 and the The lower half portion of the solid matrix 3 of two chambers 2, when mixed liquor is in almost when solidifying state paste, dismounting is located at the upper casing of inside Body completes sealing up for safekeeping for subsequent liquid cleaner and solid union enzyme.
In the present invention, such as table is selected from for configuring the raw material components of liquid cleaner, solid union enzyme and solid matrix 3 Following information shown in 1:
Table 1: solid cleaner raw material sources list is prepared
Solid cleaner is prepared using above-mentioned preparation method by the component ratio in following embodiment.
Embodiment one
(1) fluid chamber 1, the component including following mass fraction:
It (2) is 100% solid complex enzyme in multienzyme chamber (2), solid complex enzyme is Novi's letterCNS 8.0T。
(3) further, solid cleaner substrate (3) includes the component of following mass fraction:
Embodiment two
(1) fluid chamber 1, the component including following mass fraction:
It (2) is 100% solid complex enzyme in multienzyme chamber (2), solid complex enzyme is that Novi believes Medley Esstential 100T。
(3) further, solid cleaner substrate (3) includes the component of following mass fraction:
By above-mentioned two embodiment solid cleaner produced on the market liquid multienzyme cleaning agent cleaning effect, Chelating ability, biomembrane removal energy-absorbing are evaluated, and as a result see the table below 2.
Cleaning effect evaluation method: dilution being placed in isothermal vibration device and is heated to 50 degrees Celsius, places stf card, 5min is shaken, observation is taken out.Observation red whether there is, and determine cleaning effect with the red stain removal time.
Chelating ability method: the multienzyme cleaning agent detergent of injection different brands is subsequent in calcium solution (400ppm), adds The carbanion solution for entering corresponding high concentration is heated to 50 DEG C, is kept at least 18 hours.Filter off the calcium carbonate formed.Analysis Calcium content after filtering in solution calculates the percentage of calcium content.
Solution rate presses practical solid cleaner solution rate.
Table 2: the cleaning effect of present invention solid cleaner produced
Embodiment one Embodiment two Product A Product B Products C
Cleaning effect 7min 6.5min 7.5min 8min 9min
Chelating ability 90% 95% 90% 60% 70%
ATP result 9~20RLU 10~15RLU 25~55RLU 35~105RLU 45~98RLU
Dissolution time 5.5min 5min 2s 2s 2s
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent thereof.

Claims (9)

1. a kind of medical instrument solid cleaner, it is characterised in that: the solid matrix (3) including stereochemical structure is consolidated in described The inside of state matrix (3) is provided with two independent accommodating cavities, is respectively intended to place the first chamber for sealing package liquid cleaner up for safekeeping The second chamber (2) of room (1) and solid union enzyme.
2. a kind of medical instrument solid cleaner according to claim 1, it is characterised in that: use water-soluble film by institute The liquid cleaner or solid union enzyme stated, which seal up for safekeeping, to be placed in first chamber (1) or second chamber (2).
3. a kind of medical instrument solid cleaner according to claim 1, it is characterised in that: the liquid cleaner presses matter Measuring percentage includes following components:
5%~30% polyoxyethylene ether, 1~5% decontamination synergist, 1%~10% antirust agent, 1%~3% sterilization Agent, 1%~3% chelating agent, 0.1%~0.5% water and a small amount of solvent.
4. a kind of medical instrument solid cleaner according to claim 3, it is characterised in that: the polyoxyalkyl ether Molecular structural formula is R- (OC2H4)x–(OC3H6)Y-OH；
Wherein, R indicates C8-C18Line style or branched-alkyl, the number that the number of X is selected from 3~20, Y be selected from 0~15.
5. a kind of medical instrument solid cleaner according to claim 3, it is characterised in that: the chelating agent is trimerization Sodium phosphate, four sodium of glutamic acid diacetic acid, methyl-glycine diacetate tri-sodium and α-sodium glucoheptonate one or several kinds are mixed Close object.
6. a kind of medical instrument solid cleaner according to claim 2, it is characterised in that: the fungicide non-formaldehyde is released Put class fungicide, chloro- -3 ketone of -4 isothiazoline of 2 methyl of 5-, 2-methyl-4-isothiazolin-3-one, 1,2- benzisothiazole - One of 3- ketone or several mixtures.
7. a kind of medical instrument solid cleaner according to claim 1, it is characterised in that: the solid union enzyme packet Include the two or more mixture in protease, amylase, cellulase and lipase.
8. a kind of medical instrument solid cleaner according to claim 1, it is characterised in that: the solid matrix (3) By mass percentage include following components:
9. preparing a kind of described in any item medical instrument solid cleaners of claim 1-8, comprising the following steps:
(1) it seals liquid cleaner up for safekeeping: polyoxyethylene ether, decontamination synergist, antirust agent, fungicide, chelating agent, water and solvent is existed It is mixed evenly in stirred tank and mixed liquid is made, liquid is transferred in the mold A on the first molding machine later, using water Soluble film seals Aqueous cleaning liquid；
(2) it seals solid union enzyme up for safekeeping: in the mold B on the second molding machine, a variety of biological enzyme will be mixed using water-soluble film Powder is sealed；
(3) solid cleaner is prepared:
3-1: solid matrix (3) are prepared: by NaOH, Na2CO3, sodium metasilicate, sodium sulphate, sodium citrate, paraffin, polyethylene glycol and Water is put into stirred tank by allocation ratio, 50~60 DEG C at a temperature of be uniformly mixed；Mixed liquor is put into later and is capable of forming It is cooled down in the mold C of first chamber (1) and second chamber (2)；
3-2: when mixed liquor cooling in mold C is in paste, envelope is respectively put into first chamber (1) and second chamber (2) The liquid cleaner and solid union enzyme deposited, later in the mixed liquor of mold C Surface covering solid matrix (3) until cooling.
CN201811213747.XA 2018-10-18 2018-10-18 A kind of medical instrument solid cleaner and preparation method thereof Pending CN109401858A (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1409682A (en) * 1999-11-17 2003-04-09 雷克特本克斯尔(英国)有限公司 Injection-moulded water soluble container
CN108192771A (en) * 2018-02-23 2018-06-22 南京巨鲨显示科技有限公司 A kind of two chamber multienzyme of surgical instrument coagulates pearl and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1409682A (en) * 1999-11-17 2003-04-09 雷克特本克斯尔(英国)有限公司 Injection-moulded water soluble container
CN108192771A (en) * 2018-02-23 2018-06-22 南京巨鲨显示科技有限公司 A kind of two chamber multienzyme of surgical instrument coagulates pearl and preparation method thereof

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