CN109486563A - A kind of scope multienzyme cleaning agent and preparation method thereof - Google Patents

A kind of scope multienzyme cleaning agent and preparation method thereof Download PDF

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Publication number
CN109486563A
CN109486563A CN201811213627.XA CN201811213627A CN109486563A CN 109486563 A CN109486563 A CN 109486563A CN 201811213627 A CN201811213627 A CN 201811213627A CN 109486563 A CN109486563 A CN 109486563A
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scope
cleaning agent
multienzyme cleaning
added
agent
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CN201811213627.XA
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Inventor
王卫
施君君
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Nanjing Jusha Display Technology Co Ltd
Nanjing Jusha Medical Technology Co Ltd
Nanjing Jusha Commercial and Trading Co Ltd
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Nanjing Jusha Display Technology Co Ltd
Nanjing Jusha Medical Technology Co Ltd
Nanjing Jusha Commercial and Trading Co Ltd
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Priority to CN201811213627.XA priority Critical patent/CN109486563A/en
Publication of CN109486563A publication Critical patent/CN109486563A/en
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    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/825—Mixtures of compounds all of which are non-ionic
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/02—Inorganic compounds ; Elemental compounds
    • C11D3/04—Water-soluble compounds
    • C11D3/06—Phosphates, including polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/162—Organic compounds containing Si
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2003—Alcohols; Phenols
    • C11D3/2041—Dihydric alcohols
    • C11D3/2044—Dihydric alcohols linear
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2003—Alcohols; Phenols
    • C11D3/2065—Polyhydric alcohols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2068—Ethers
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/26—Organic compounds containing nitrogen
    • C11D3/33—Amino carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/34—Organic compounds containing sulfur
    • C11D3/349—Organic compounds containing sulfur additionally containing nitrogen atoms, e.g. nitro, nitroso, amino, imino, nitrilo, nitrile groups containing compounds or their derivatives or thio urea
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/36—Organic compounds containing phosphorus
    • C11D3/362—Phosphates or phosphites
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers
    • C11D3/3746—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3757—(Co)polymerised carboxylic acids, -anhydrides, -esters in solid and liquid compositions
    • C11D3/3765—(Co)polymerised carboxylic acids, -anhydrides, -esters in solid and liquid compositions in liquid compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618—Protease or amylase in liquid compositions only
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38645—Preparations containing enzymes, e.g. protease or amylase containing cellulase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/72—Ethers of polyoxyalkylene glycols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/72—Ethers of polyoxyalkylene glycols
    • C11D1/721—End blocked ethers
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/75—Amino oxides

Abstract

The invention discloses a kind of scope multienzyme cleaning agents and preparation method thereof, the scope multienzyme cleaning agent configured includes 1%~10% solubilizer, 5%~30% polyoxyethylene ether, 1%~10% low foaming surfactant, 1~5% amine-oxides class surfactant, 1%~10% defoaming agent, 5%~15% Combizym, 1%~3% fungicide, 1%~3% antirust agent, 1%~3% chelating agent and 2%~15% solvent.Required scope multienzyme cleaning agent is stirred to get by the way that above each component to be added in stirred tank by step.The cleaning agent that the present invention is configured has many advantages, such as Low-foam and easily rinsing, high-effective cleansing, removal biomembrane.

Description

A kind of scope multienzyme cleaning agent and preparation method thereof
Technical field
The invention belongs to medical cleaning agent fields, and in particular to a kind of scope multienzyme cleaning agent and preparation method thereof.
Background technique
Endoscope after use, the human body in surface and pipeline in normal remained blood, mucus and biopsy hole and suction hole Tissue.And scope will lead to the accumulation for bringing biomembrane in Reusability, it is worth mentioning at this point that, general cleaning method is very Difficulty is thoroughly removed biomembrane.Biomembrane have very big harmfulness, it is estimated that 65% human body bacterium infection all with biology Film is related.After biofilm formation, need 2400 times of antibiotic dosage, in many institutes the outburst of scope infections relating be all with clearly Wash be not thorough it is closely related.
Preferably removal Biofilm Environment is that enzyme cleaning agent is used when scope is cleaned on the market at present.But due to The regulation of medical cleaning agent is not perfect, and the scope multienzyme cleaning agent of many producers more or less all has some problems, such as Foam is excessively high to cause automatic occasion of rinsing device to be alarmed, and rinsing liquid is not thorough enough, influences subsequent Disinfection Effect；Detergency does not cause by force Dirt remains in endoscope surface；It only uses a kind of enzyme or cleaning force does not cause by force to remove biomembrane and is not thorough；It is rinsability poor Cause cleaning agent part to remain in endoscope surface, causes scope metal surface to be shaded, influence subsequent disinfection process.
Summary of the invention
In view of the above-mentioned problems, the present invention is configured with a kind of scope multienzyme cleaning agent and preparation method thereof.
It realizes above-mentioned technical purpose, reaches above-mentioned technical effect, the invention is realized by the following technical scheme:
A kind of scope multienzyme cleaning agent includes following component according to mass percentage content: 1%~10% solubilizer, 1%~10% low foaming surfactant, 5%~30% polyoxyethylene ether, 1~5% amine-oxides class surfactant, 1% ~10% defoaming agent, 5%~15% Combizym, 1%~3% fungicide, 1%~3% antirust agent, 1%~3% Chelating agent and 2%~15% solvent.
As a further improvement of the present invention, the low foaming surfactant is using C8~C20 alcohol polyoxyethylene Ether butyl end-capping.
As a further improvement of the present invention, the Combizym is to include amylase, protease, cellulase, rouge The mixture of four kinds of enzymes of fat enzyme, in mass ratio 7:2:1~2:1 are mixed.
As a further improvement of the present invention, the molecular structural formula of the polyoxyethylene ether is R- (OC2H4) x-OH；Its In, R indicates that the line style or branched-alkyl of C8-C18, the number of X are selected from 3~9.
As a further improvement of the present invention, the amine-oxides class surfactant is selected from N, N- dimethyl dodecyl base Amine-oxides, N, N- dimethyl tetradecyl base amine-oxides, N, any one of N- dimethyl hexadecyl base amine-oxides.
As a further improvement of the present invention, the fungicide is selected from non-formaldehyde release class fungicide, chloro- 2 methyl-of 5- One of -3 ketone of 4 isothiazoline, 2-methyl-4-isothiazolin-3-one, 1,2- benzisothiazole-3-ketone are several mixed Close object.
As a further improvement of the present invention, the chelating agent be selected from sodium tripolyphosphate, four sodium of glutamic acid diacetic acid and One of methyl-glycine diacetate tri-sodium or several mixtures.
As a further improvement of the present invention, the solvent is organic solvent soluble easily in water, is selected from glycerol, propylene glycol, second Any one or more of glycol, propandiol butyl ether, dipropylene.
A method of preparing a kind of above-described scope multienzyme cleaning agent, comprising the following steps:
S1: solubilizer and water are added in stirred tank, and heating stirring is until dissolution；
S2: polyoxyethylene ether, low foaming surfactant, defoaming agent, amine-oxides class surfactant and molten are proportionally added into Agent, stirring to dissolution；
S3: chelating agent is added and is stirred until homogeneous；
S4: Combizym mixed liquor is added after dropping to room temperature and fungicide is stirred to dissolution；
S5: antirust agent is added and stirs to dissolution；
S6: while stirring, the scope multienzyme cleaning agent configured is diluted with water.
Further, amylase in mass ratio: protease: cellulase: lipase=7:2:1~2:1 ratio is mixed Close the configuration Combizym.
Beneficial effects of the present invention: cleaning agent provided by the present invention, surfactant, solubilizer system in make The substances such as complex enzyme, fungicide and chelating agent more preferably contact biomembrane faster.Have using complex enzyme energy decomposing organism film surface Machine substance, fungicide can then kill exposed bacterium in biomembrane, while cooperate on chelant ties bacterial cell membrane Calcium ion reaches better bactericidal effect to enable the easier inside for penetrating into bacterium of fungicide.Wherein we also use Defoaming agent turns down cleaning foam and increases easily rinsability, to reach Low-foam and easily rinsing, high-effective cleansing, removal biomembrane etc. are excellent Point.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
In following embodiment, the component for configuring the raw material of scope multienzyme cleaning agent is specifically as shown in table 1:
Table 1: scope multienzyme cleaning agent source list is prepared
Embodiment one
(1) scope multienzyme cleaning agent, the component including following mass fraction:
(2) preparation method:
S1: being added 8%Triton H-66 after suitable water is added into the stirred tank after disinfection, is warming up to 45 DEG C, stirring To dissolution.S2: respectively by 5% surfactant LF221,2%Dehypon LS104,1%N, the oxidation of N- dimethyl dodecyl base Ammonium, 15% propylene glycol are added in stirred tank, stirring to dissolution.
S3: 3% sodium tripolyphosphate is added and is uniformly mixed.
S4: it drops to after room temperature and is added 12% Combizym and 3% Kathon CG is stirred to dissolution, wherein Combizym ratio are as follows: Protease: lipase: amylase: cellulase=7:2:1:1.
S5: 1% antirust agent Corrguard SI and 0.1%AFE-1247 is added and stirs to dissolution.
S5: the water for adding surplus is diluted, and is filtered after being stirred for half an hour, and scope multienzyme cleaning agent is obtained.
Embodiment two
(1) scope multienzyme cleaning agent, the component including following mass fraction:
(2) preparation method
S1: 1%Deriphat 160C is added after suitable water is added into the stirred tank after disinfection, is warming up to 45 DEG C, stirs It mixes to dissolution.S2: respectively by 30% surfactant LF221,10%Dehypon LS104,5%N, N- dimethyl tetradecyl base Amine-oxides, 2% glycerol are added in stirred tank, stirring to dissolution.
S3: 1%GL47 is added and is uniformly mixed.
S4: it drops to after room temperature and is added 5% Combizym and 1% Kathon CG is stirred to dissolution, wherein Combizym ratio are as follows: egg White enzyme: lipase: amylase: cellulase=7:2:1:1.
S5: 1%Corrguard SI and 0.1%AFE-1226 is added and stirs to dissolution.
S5: the water for adding surplus is diluted, and is filtered after being stirred for half an hour, and scope multienzyme cleaning agent is obtained.
Embodiment 3
(1) scope multienzyme cleaning agent, the component including following mass fraction:
(2) preparation method
S1: 10%Emulsogen HCO040 is added after suitable water is added into the stirred tank after disinfection, is warming up to 45 DEG C, stirring to dissolution.S2: respectively by 5% surfactant LF401,2%Dehypon LS104L, 1%N, N- dimethyl 16 Alkyl amine-oxides, 15% glycerol are added in stirred tank, stirring to dissolution.
S3: 3%GL47 is added and is uniformly mixed.
S4: it drops to after room temperature and is added 10% Combizym and 3%Proxel GXL is stirred to dissolution, wherein Combizym ratio Example are as follows: protease: lipase: amylase: cellulase=7:2:2:1.
S5: 3%190P and 0.1%AFE-1267 is added and stirs to dissolution.
S5: the water for adding surplus is diluted, and is filtered after being stirred for half an hour, and scope multienzyme cleaning agent is obtained.
After stirred tank cleaning and sterilizing, it is first passed through the water of half, turn on agitator is rear that 10% solubilizer is added, and is warming up to 45 DEG C, stirring is to dissolving, respectively by 5% surfactant LF401,2%Dehypon LS104L, 1%N, N- dimethyl hexadecyl Base amine-oxides, 15% glycerol are added in stirred tank, and stirring adds 3%GL47, Combizym is added after dropping to room temperature to dissolving 10% and 3%Proxel GXL is stirred to dissolution, wherein Combizym ratio are as follows: 7:2:2:1 adds the stirring of 3% antirust agent To dissolution, then the water of surplus is added, filtered after being stirred for half an hour, obtains scope multienzyme cleaning agent.
By cleaning agent prepared by three of the above embodiment and multienzyme cleaning agent on the market in cleaning effect, sequestering Energy, biomembrane removal energy-absorbing are evaluated, and the results are shown in Table 2.
Cleaning effect evaluation method: dilution being placed in isothermal vibration device and is heated to 50 degrees Celsius, places stf card, 5min is shaken, observation is taken out.Observation red whether there is, and determine cleaning effect with the red stain removal time.Chelating ability side Method: the multienzyme cleaning agent detergent of injection different brands is subsequent in calcium solution (400ppm), and the carbonic acid of corresponding high concentration is added Radical ion solution is heated to 50 DEG C, is kept at least 18 hours.Filter off the calcium carbonate formed.Calcium after analysis filtering in solution contains Amount, calculates the percentage of calcium content.
Removal effect test of the biomembrane removal effect using ATP test and blood and bacterial mixture, specific test side Method is shown in medical cleaning agent standard (declaration version).
Table 2: the cleaning effect of present invention cleaning agent produced
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent thereof.

Claims (10)

1. a kind of scope multienzyme cleaning agent, includes following component according to mass percentage content:
1%~10% solubilizer, 1%~10% low foaming surfactant, 5%~30% polyoxyethylene ether, 1~5% Amine-oxides class surfactant, 1%~10% defoaming agent, 5%~15% Combizym, 1%~3% fungicide, 1% ~3% antirust agent, 1%~3% chelating agent and 2%~15% solvent.
2. a kind of scope multienzyme cleaning agent according to claim 1, it is characterised in that: the low foaming surfactant is adopted It is C8~C20 alcohol polyoxyethylene ether butyl end-capping.
3. a kind of scope multienzyme cleaning agent according to claim 1, it is characterised in that: the Combizym is comprising forming sediment Powder enzyme, protease, cellulase, four kinds of enzymes of lipase mixture, 7:2:1~2:1 in mass ratio mixed.
4. a kind of scope multienzyme cleaning agent according to claim 1, it is characterised in that: the molecule of the polyoxyethylene ether Structural formula is R- (OC2H4)x-OH；
Wherein, R indicates C8-C18Line style or branched-alkyl, the number of X be selected from 3~9.
5. a kind of scope multienzyme cleaning agent according to claim 1, it is characterised in that: the amine-oxides class surface-active Agent is selected from N, N- dimethyl dodecyl base amine-oxides, N, N- dimethyl tetradecyl base amine-oxides, N, N- dimethyl hexadecyl base oxygen Change any one of ammonium.
6. a kind of scope multienzyme cleaning agent according to claim 1, it is characterised in that: the fungicide is selected from non-formaldehyde Discharge class fungicide, chloro- -3 ketone of -4 isothiazoline of 2 methyl of 5-, 2-methyl-4-isothiazolin-3-one, 1,2- benzisothiazole One of quinoline -3- ketone or several mixtures.
7. a kind of scope multienzyme cleaning agent according to claim 1, it is characterised in that: the chelating agent is selected from trimerization phosphorus One of sour sodium, four sodium of glutamic acid diacetic acid and methyl-glycine diacetate tri-sodium or several mixtures.
8. a kind of scope multienzyme cleaning agent according to claim 1, it is characterised in that: the solvent is soluble easily in water organic Solvent is selected from any one or more of glycerol, propylene glycol, ethylene glycol, propandiol butyl ether, dipropylene.
9. a kind of prepare a kind of described in any item methods of scope multienzyme cleaning agent of claim 1-8, comprising the following steps:
S1: solubilizer and water are added in stirred tank, and heating stirring is until dissolution；
S2: it is proportionally added into polyoxyethylene ether, low foaming surfactant, defoaming agent, amine-oxides class surfactant and solvent, is stirred It mixes to dissolution；
S3: chelating agent is added and is stirred until homogeneous；
S4: Combizym mixed liquor is added after dropping to room temperature and fungicide is stirred to dissolution；
S5: antirust agent is added and stirs to dissolution；
S6: while stirring, the scope multienzyme cleaning agent configured is diluted with water.
10. preparation method according to claim 9, it is characterised in that: amylase in mass ratio: protease: cellulase: Lipase=7:2:1~2:1 ratio carries out Combizym described in mixed configuration.
CN201811213627.XA 2018-10-18 2018-10-18 A kind of scope multienzyme cleaning agent and preparation method thereof Pending CN109486563A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110003991A (en) * 2019-04-23 2019-07-12 南京巨鲨显示科技有限公司 A kind of medical multienzyme cleaning cream and preparation method thereof removing the heavy scale
CN111171978A (en) * 2020-01-07 2020-05-19 南京巨鲨显示科技有限公司 Cleaning agent for cleaning methyl silicone oil of soft endoscope and preparation method thereof
CN111560292A (en) * 2020-05-08 2020-08-21 南京巨鲨显示科技有限公司 Special foamless multienzyme cleaning agent for reduced pressure boiling and preparation method thereof
CN112011410A (en) * 2020-07-29 2020-12-01 韩兴宏 Preparation method of environment-friendly hexadecyl industrial detergent
CN112391241A (en) * 2019-08-16 2021-02-23 3M创新有限公司 Liquid cleaning composition and method of making same
CN114164060A (en) * 2021-11-15 2022-03-11 山东消博士消毒科技股份有限公司 Medical multienzyme cleaning agent and large-scale mixer thereof
CN115247106A (en) * 2022-01-15 2022-10-28 郑州大学第一附属医院 Endoscope multienzyme cleaning composition and application thereof
CN115558559A (en) * 2021-12-08 2023-01-03 上海利康消毒高科技有限公司 Compound multienzyme biomembrane scavenger

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101696371A (en) * 2009-10-26 2010-04-21 广州泰成生化科技有限公司 Lubricating detergent, preparation method and application thereof
CN103261392A (en) * 2010-12-28 2013-08-21 花王株式会社 Method for cleaning medical appliance
CN103484267A (en) * 2013-09-12 2014-01-01 广东环凯微生物科技有限公司 Multienzyme cleaning solution special for endoscope cleaning and disinfection machine and preparation process of multienzyme cleaning solution
CN104073366A (en) * 2013-12-05 2014-10-01 成都老肯科技股份有限公司 Alkaline cleaner suitable for cleaning medical appliance and preparation method thereof
CN105121353A (en) * 2013-03-07 2015-12-02 鲁沃夫公司 Methods and enzymatic detergents for removing biofilm
CN106281761A (en) * 2016-08-19 2017-01-04 南京巨鲨显示科技有限公司 A kind of medical apparatus and instruments multienzyme cleaning agent and preparation method thereof
CN106456667A (en) * 2014-06-24 2017-02-22 3M创新有限公司 Low foaming multi enzymatic cleaner
CN106544164A (en) * 2016-11-02 2017-03-29 广州润虹医药科技有限公司 A kind of high-effective low foam antibacterial type multienzyme cleaning agent and its preparation technology

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101696371A (en) * 2009-10-26 2010-04-21 广州泰成生化科技有限公司 Lubricating detergent, preparation method and application thereof
CN103261392A (en) * 2010-12-28 2013-08-21 花王株式会社 Method for cleaning medical appliance
CN105121353A (en) * 2013-03-07 2015-12-02 鲁沃夫公司 Methods and enzymatic detergents for removing biofilm
CN103484267A (en) * 2013-09-12 2014-01-01 广东环凯微生物科技有限公司 Multienzyme cleaning solution special for endoscope cleaning and disinfection machine and preparation process of multienzyme cleaning solution
CN104073366A (en) * 2013-12-05 2014-10-01 成都老肯科技股份有限公司 Alkaline cleaner suitable for cleaning medical appliance and preparation method thereof
CN106456667A (en) * 2014-06-24 2017-02-22 3M创新有限公司 Low foaming multi enzymatic cleaner
CN106281761A (en) * 2016-08-19 2017-01-04 南京巨鲨显示科技有限公司 A kind of medical apparatus and instruments multienzyme cleaning agent and preparation method thereof
CN106544164A (en) * 2016-11-02 2017-03-29 广州润虹医药科技有限公司 A kind of high-effective low foam antibacterial type multienzyme cleaning agent and its preparation technology

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110003991A (en) * 2019-04-23 2019-07-12 南京巨鲨显示科技有限公司 A kind of medical multienzyme cleaning cream and preparation method thereof removing the heavy scale
CN112391241A (en) * 2019-08-16 2021-02-23 3M创新有限公司 Liquid cleaning composition and method of making same
CN111171978A (en) * 2020-01-07 2020-05-19 南京巨鲨显示科技有限公司 Cleaning agent for cleaning methyl silicone oil of soft endoscope and preparation method thereof
CN111560292A (en) * 2020-05-08 2020-08-21 南京巨鲨显示科技有限公司 Special foamless multienzyme cleaning agent for reduced pressure boiling and preparation method thereof
CN112011410A (en) * 2020-07-29 2020-12-01 韩兴宏 Preparation method of environment-friendly hexadecyl industrial detergent
CN114164060A (en) * 2021-11-15 2022-03-11 山东消博士消毒科技股份有限公司 Medical multienzyme cleaning agent and large-scale mixer thereof
CN115558559A (en) * 2021-12-08 2023-01-03 上海利康消毒高科技有限公司 Compound multienzyme biomembrane scavenger
CN115247106A (en) * 2022-01-15 2022-10-28 郑州大学第一附属医院 Endoscope multienzyme cleaning composition and application thereof

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