CN109394554A - A kind of probiotics toothpaste and preparation method thereof - Google Patents
A kind of probiotics toothpaste and preparation method thereof Download PDFInfo
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- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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Abstract
The invention discloses a kind of probiotics toothpaste and preparation method thereof, are composed of the following raw materials in parts by weight: 50-60 parts of silicic acid hydrate, 50-60 parts of aluminium hydroxide, and 50-60 parts of lac resin, 20-30 parts of pectin；3-5 parts of moisturizer, 3-5 parts of sodium lauryl sulfonate, 5-8 parts of sodium carboxymethylcellulose, 3-5 parts of Peppermint essential oil, 0.5-2 parts of sweetener, 1-2 parts of chlorophyll, 10-15 parts and deionized water 50-80 parts of Freeze-dry Powder of Probioctics.There are also pectin and lac resins other than containing friction particles in toothpaste of the invention, the surface of process of brushing teeth Tooth is in addition to the film that is made of there are also one layer colloid and adhesive particle and foam, the presence of film avoid toothbrush bristle directly and tooth surface contact, toothbrush is evenly dispersed and is buffered by film to the active force of tooth, will not be damaged to tooth.Reduce the injury of toothpaste and toothbrush to sensitive teeth, gum.
Description
Technical field
The present invention relates to the present invention relates to a kind of field of oral care, more particularly, to a kind of probiotics toothpaste and its preparation
Method.
Background technique
Tooth is one of maximum organ of human senility speed difference, other than inherent cause, living habit, to tooth
Nursing care mode etc., factor is the largest to the health and aging effects of tooth.Mistake teeth brushing way: 1, long term lateral is brushed teeth,
2, it brushes teeth really up to the mark using toothbrush, 3, brushing teeth overexerts.Due to overexertion during brushing teeth, tooth is caused to be brushed off.Toothpaste
Improper use causes oral cavity bacterium accumulation and the generation of dental caries.The acid-resisting of dental calcium can be enhanced in fluorine, while inhibiting bacterium
Fermentation generate acid, therefore can firm bone and tooth, in order to prevent and treat saprodontia, fluoride is begun to appear in toothpaste.Allow science
Family is quite unexpected, and fluorine shows dual character quickly: eurodonticus is fewer and fewer, and den tal fluorosis patient is more and more.Fluorine
Dental plaque is primary warning of the fluoride to people, and more frighteningly, the long-term fluoride for taking in high dose may cause nerve
Disease and endocrine system malfunction.
Summary of the invention
In view of this, being solved general in view of the deficiencies of the prior art, it is an object of the present invention to provide a kind of probiotics toothpaste
Logical toothpaste cannot pre- anti-caries problem avoid the harm of toothpaste with fluoride bring is used for a long time simultaneously, and joined into toothpaste
Film glue, can be attached to the surface of tooth and toothbrush bristle, effectively slow down because the improper teeth brushing way such as overexert makes tooth
At damage, while avoiding toothpaste to sensitive gum, the stimulation of tooth.
In order to achieve the above objectives, the invention adopts the following technical scheme:
A kind of probiotics toothpaste, is composed of the following raw materials in parts by weight: 50-60 parts of silicic acid hydrate, aluminium hydroxide 50-60
Part, 50-60 parts of lac resin, 20-30 parts of pectin；3-5 parts of moisturizer, 3-5 parts of sodium lauryl sulfonate, sodium carboxymethylcellulose 5-
8 parts, 3-5 parts of Peppermint essential oil, 0.5-2 parts of sweetener, 1-2 parts of chlorophyll, 10-15 parts of Freeze-dry Powder of Probioctics and deionized water 50-
80 parts.
Further, the sweetener be etc. parts by weight stevioside and chrysanthemum flower extract mixing.
Further, the composition of the moisturizer are as follows: 6-8 parts of sorbierite, 4-5 parts of lecithin, 3-5 parts of chitosan, silk gum
2-3 parts of powder, 2-3 parts and deionized water 8-10 parts of marine algae extract；Preparation method is to mix the raw material of the parts by weight, is added
It is water-swellable to obtain the final product.
Lac resin of the present invention derives from Resources Insect Inst., Chinese Academy of Forestry Sciences's Specialty bio resource
Pilot Base is researched and developed to provide；The quality index of lac resin is as follows: hot ethanol insoluble matter (%)≤3；Volatile matter (moisture)
(%)≤2.5；Thermmohardening time (170 DEG C ± 0.5 DEG C) (min) >=7 hydrotrope (%)≤1；Wax (%)≤5.5；Acid value
(mg/g) 75~90；Rosin: nothing.
The preparation of the Freeze-dry Powder of Probioctics and its Activity determination are shown in Chinese patent CN 105434322B.
The present invention also provides the preparation methods of the probiotics toothpaste, include the following steps:
Step 1: glue: sodium carboxymethylcellulose, lac resin, pectin and sodium lauryl sulfonate are put into size making pot,
It is added deionized water under high-speed stirred, stirring to glue homogeneous transparent until no powder, then places a period of time, allows micelle
Sufficiently used after swelling；
Step 2: it mediates: glue being squeezed into kneader, silicic acid hydrate, aluminium hydroxide, moisturizer, Peppermint essential oil, sweet tea is added
Taste agent, chlorophyll and Freeze-dry Powder of Probioctics are mediated uniform；
Step 3: grinding: the lotion through mediating by gear pump or is back and forth pumped into colloid mill and is ground；In machinery
Under shearing force, makes the further homogeneous dispersion of the agglomerated masses of colloid or powder, reach the various particles in lotion and be uniformly distributed, grind
A period of time is placed after mill, the bubble for keeping subtle bubble auto-polymerization big reduces the total surface area of bubble, in favor of
The progress of next step degassing process；
Step 4: vacuum outgas: by the lotion vacuum outgas after grinding, until vacuum degree reaches -0.096Mpa or more, time
About 50 minutes；The operation is the molding situation in order to improve lotion, and degassed treated lotion is bright fine and smooth, stripping
It is good；
Step 5: canned packaging: the lotion after degassing can be packed into hose by automatic filling machine after standing, and carry out
Spotweld is or folding tail, the toothpaste after filling sealing are packed by manual or automatic packing machine.
Further, kneading time described in step 2 is 20-25 minutes.
Further, placement a period of time described in step 3 is 20-30 minutes.
The beneficial effects of the present invention are:
1. there are also pectin and lac resin, process of brushing teeth Tooths other than containing friction particles in toothpaste of the invention
Surface in addition to the film being made of there are also one layer colloid and adhesive particle and foam, it is straight that the presence of film avoids toothbrush bristle
It connects and tooth surface contact, toothbrush is evenly dispersed and is buffered by film to the active force of tooth, will not damaged to tooth.
Reduce the injury of toothpaste and toothbrush to sensitive teeth, gum.
2. can effectively kill oral cavity harmful bacteria rich in Freeze-dry Powder of Probioctics in toothpaste, retain a large amount of beneficial bacteriums, effectively
Improve oral environment.
3. the most important effect of sodium carboxymethylcellulose CMC is dirt-carrying effect, CMC is added in toothpaste, then when brushing teeth,
CMC is adsorbed on the surface of tooth while being also attracted to the surface of dirt particles, and another aspect CMC also has thickening, dispersion, cream
Change, the effect of suspension and stable foam, these effects can make dirt is stable to be suspended in solution, more difficult to occur to sink
Product.
4. being rich in natural freshener in toothpaste, oral cavity can be made persistently fragrant and sweet, breath freshening.
5. moisturizer has certain inoxidizability simultaneously, there is the oxidation of anti-tooth, beauty while keeping toothpaste viscosity
White effect.
Specific embodiment
Embodiment 1
A kind of probiotics toothpaste, is composed of the following raw materials in parts by weight: 50 parts of silicic acid hydrate, 50 parts of aluminium hydroxide, and lac
50 parts of resin, 20 parts of pectin；3 parts of moisturizer, 3 parts of sodium lauryl sulfonate, 5 parts of sodium carboxymethylcellulose, 3 parts of Peppermint essential oil, sweet tea
0.5 part of taste agent, 1 part of chlorophyll, 10 parts and 50 parts of deionized water of Freeze-dry Powder of Probioctics.
The sweetener be etc. parts by weight stevioside and chrysanthemum flower extract mixing.
The composition of the moisturizer are as follows: 6 parts of sorbierite, 4 parts of lecithin, 3 parts of chitosan, 2 parts of sericin powder, marine algae extract
2 parts and 8 parts of deionized water；Preparation method is to mix the raw materials of the parts by weight, add it is water-swellable to obtain the final product.
The present invention also provides the preparation methods of the probiotics toothpaste, include the following steps:
Step 1: glue: sodium carboxymethylcellulose, lac resin, pectin and sodium lauryl sulfonate are put into size making pot,
It is added deionized water under high-speed stirred, stirring to glue homogeneous transparent until no powder, then places a period of time, allows micelle
Sufficiently used after swelling；
Step 2: it mediates: glue being squeezed into kneader, silicic acid hydrate, aluminium hydroxide, moisturizer, Peppermint essential oil, sweet tea is added
Taste agent, chlorophyll and Freeze-dry Powder of Probioctics are mediated uniform；Kneading time described in step 2 is 20 minutes；
Step 3: grinding: the lotion through mediating by gear pump or is back and forth pumped into colloid mill and is ground；In machinery
Under shearing force, makes the further homogeneous dispersion of the agglomerated masses of colloid or powder, reach the various particles in lotion and be uniformly distributed, grind
It to be placed after mill 20 minutes, the bubble for keeping subtle bubble auto-polymerization big reduces the total surface area of bubble, in favor of under
The progress of one step degassing process；
Step 4: vacuum outgas: by the lotion vacuum outgas after grinding, until vacuum degree is up to -0.096Mpa, time
It is 50 minutes；The operation is the molding situation in order to improve lotion, and degassed treated lotion is bright fine and smooth, and stripping is good；
Step 5: canned packaging: the lotion after degassing can be packed into hose by automatic filling machine after standing, and carry out
Spotweld is or folding tail, the toothpaste after filling sealing are packed by manual or automatic packing machine.
Embodiment 2
A kind of probiotics toothpaste, is composed of the following raw materials in parts by weight: 60 parts of silicic acid hydrate, 60 parts of aluminium hydroxide, and lac
60 parts of resin, 30 parts of pectin；5 parts of moisturizer, 5 parts of sodium lauryl sulfonate, 8 parts of sodium carboxymethylcellulose, 5 parts of Peppermint essential oil, sweet tea
2 parts of taste agent, 2 parts of chlorophyll, 15 parts and 80 parts of deionized water of Freeze-dry Powder of Probioctics.
The sweetener be etc. parts by weight stevioside and chrysanthemum flower extract mixing.
The composition of the moisturizer are as follows: 8 parts of sorbierite, 5 parts of lecithin, 5 parts of chitosan, 3 parts of sericin powder, marine algae extract
3 parts and 10 parts of deionized water；Preparation method is to mix the raw materials of the parts by weight, add it is water-swellable to obtain the final product.
The present invention also provides the preparation methods of the probiotics toothpaste, include the following steps:
Step 1: glue: sodium carboxymethylcellulose, lac resin, pectin and sodium lauryl sulfonate are put into size making pot,
It is added deionized water under high-speed stirred, stirring to glue homogeneous transparent until no powder, then places a period of time, allows micelle
Sufficiently used after swelling；
Step 2: it mediates: glue being squeezed into kneader, silicic acid hydrate, aluminium hydroxide, moisturizer, Peppermint essential oil, sweet tea is added
Taste agent, chlorophyll and Freeze-dry Powder of Probioctics, mediating kneading time described in homogenizing step two is 25 minutes；
Step 3: grinding: the lotion through mediating by gear pump or is back and forth pumped into colloid mill and is ground；In machinery
Under shearing force, makes the further homogeneous dispersion of the agglomerated masses of colloid or powder, reach the various particles in lotion and be uniformly distributed, grind
It to be placed after mill 30 minutes, the bubble for keeping subtle bubble auto-polymerization big reduces the total surface area of bubble, in favor of under
The progress of one step degassing process.
Step 4: vacuum outgas: by the lotion vacuum outgas after grinding, until vacuum degree is up to -0.096Mpa, time
It is 60 minutes；The operation is the molding situation in order to improve lotion, and degassed treated lotion is bright fine and smooth, and stripping is good；
Step 5: canned packaging: the lotion after degassing can be packed into hose by automatic filling machine after standing, and carry out
Spotweld is or folding tail, the toothpaste after filling sealing are packed by manual or automatic packing machine.
Embodiment 3
A kind of probiotics toothpaste, is composed of the following raw materials in parts by weight: 55 parts of silicic acid hydrate, 55 parts of aluminium hydroxide, and lac
55 parts of resin, 25 parts of pectin；4 parts of moisturizer, 4 parts of sodium lauryl sulfonate, 6 parts of sodium carboxymethylcellulose, 4 parts of Peppermint essential oil, sweet tea
1.5 parts of taste agent, 1.5 parts of chlorophyll, 12 parts and 60 parts of deionized water of Freeze-dry Powder of Probioctics.
The sweetener be etc. parts by weight stevioside and chrysanthemum flower extract mixing.
The composition of the moisturizer are as follows: 7 parts of sorbierite, 4.5 parts of lecithin, 4 parts of chitosan, 2.5 parts of sericin powder, seaweed mentions
Take 2.5 parts and 9 parts of deionized water of object；Preparation method is to mix the raw materials of the parts by weight, add it is water-swellable to obtain the final product.
The present invention also provides the preparation methods of the probiotics toothpaste, include the following steps:
Step 1: glue: sodium carboxymethylcellulose, lac resin, pectin and sodium lauryl sulfonate are put into size making pot,
It is added deionized water under high-speed stirred, stirring to glue homogeneous transparent until no powder, then places a period of time, allows micelle
Sufficiently used after swelling；
Step 2: it mediates: glue being squeezed into kneader, silicic acid hydrate, aluminium hydroxide, moisturizer, Peppermint essential oil, sweet tea is added
Taste agent, chlorophyll and Freeze-dry Powder of Probioctics, mediating kneading time described in homogenizing step two is 22 minutes；
Step 3: grinding: the lotion through mediating by gear pump or is back and forth pumped into colloid mill and is ground；In machinery
Under shearing force, makes the further homogeneous dispersion of the agglomerated masses of colloid or powder, reach the various particles in lotion and be uniformly distributed, grind
It to be placed after mill 25 minutes, the bubble for keeping subtle bubble auto-polymerization big reduces the total surface area of bubble, in favor of under
The progress of one step degassing process.
Step 4: vacuum outgas: by the lotion vacuum outgas after grinding, until vacuum degree is up to -0.096Mpa, time
It is 55 minutes；The operation is the molding situation in order to improve lotion, and degassed treated lotion is bright fine and smooth, and stripping is good；
Step 5: canned packaging: the lotion after degassing can be packed into hose by automatic filling machine after standing, and carry out
Spotweld is or folding tail, the toothpaste after filling sealing are packed by manual or automatic packing machine.
Embodiment 4
A kind of probiotics toothpaste, is composed of the following raw materials in parts by weight: 52 parts of silicic acid hydrate, 52 parts of aluminium hydroxide, and lac
52 parts of resin, 22 parts of pectin；3 parts of moisturizer, 4 parts of sodium lauryl sulfonate, 6 parts of sodium carboxymethylcellulose, 5 parts of Peppermint essential oil, sweet tea
1 part of taste agent, 1 part of chlorophyll, 11 parts and 55 parts of deionized water of Freeze-dry Powder of Probioctics.
The sweetener be etc. parts by weight stevioside and chrysanthemum flower extract mixing.
The composition of the moisturizer are as follows: 6 parts of sorbierite, 4 parts of lecithin, 5 parts of chitosan, 2 parts of sericin powder, marine algae extract
3 parts and 8 parts of deionized water；Preparation method is to mix the raw materials of the parts by weight, add it is water-swellable to obtain the final product.
The present invention also provides the preparation methods of the probiotics toothpaste, include the following steps:
Step 1: glue: sodium carboxymethylcellulose, lac resin, pectin and sodium lauryl sulfonate are put into size making pot,
It is added deionized water under high-speed stirred, stirring to glue homogeneous transparent until no powder, then places a period of time, allows micelle
Sufficiently used after swelling；
Step 2: it mediates: glue being squeezed into kneader, silicic acid hydrate, aluminium hydroxide, moisturizer, Peppermint essential oil, sweet tea is added
Taste agent, chlorophyll and Freeze-dry Powder of Probioctics, mediating kneading time described in homogenizing step two is 21 minutes；
Step 3: grinding: the lotion through mediating by gear pump or is back and forth pumped into colloid mill and is ground；In machinery
Under shearing force, makes the further homogeneous dispersion of the agglomerated masses of colloid or powder, reach the various particles in lotion and be uniformly distributed, grind
It to be placed after mill 22 minutes, the bubble for keeping subtle bubble auto-polymerization big reduces the total surface area of bubble, in favor of under
The progress of one step degassing process；
Step 4: vacuum outgas: by the lotion vacuum outgas after grinding, until vacuum degree is up to -0.096Mpa, time
It is 52 minutes；The operation is the molding situation in order to improve lotion, and degassed treated lotion is bright fine and smooth, and stripping is good；
Step 5: canned packaging: the lotion after degassing can be packed into hose by automatic filling machine after standing, and carry out
Spotweld is or folding tail, the toothpaste after filling sealing are packed by manual or automatic packing machine.
Embodiment 5
A kind of probiotics toothpaste, is composed of the following raw materials in parts by weight: 58 parts of silicic acid hydrate, 56 parts of aluminium hydroxide, and lac
54 parts of resin, 23 parts of pectin；3 parts of moisturizer, 5 parts of sodium lauryl sulfonate, 7 parts of sodium carboxymethylcellulose, 3 parts of Peppermint essential oil, sweet tea
1 part of taste agent, 1 part of chlorophyll, 14 parts and 75 parts of deionized water of Freeze-dry Powder of Probioctics.
The sweetener be etc. parts by weight stevioside and chrysanthemum flower extract mixing.
The composition of the moisturizer are as follows: 6 parts of sorbierite, 5 parts of lecithin, 4 parts of chitosan, 2 parts of sericin powder, marine algae extract
3 parts and 9 parts of deionized water；Preparation method is to mix the raw materials of the parts by weight, add it is water-swellable to obtain the final product.
The present invention also provides the preparation methods of the probiotics toothpaste, include the following steps:
Step 1: glue: sodium carboxymethylcellulose, lac resin, pectin and sodium lauryl sulfonate are put into size making pot,
It is added deionized water under high-speed stirred, stirring to glue homogeneous transparent until no powder, then places a period of time, allows micelle
Sufficiently used after swelling；
Step 2: it mediates: glue being squeezed into kneader, silicic acid hydrate, aluminium hydroxide, moisturizer, Peppermint essential oil, sweet tea is added
Taste agent, chlorophyll and Freeze-dry Powder of Probioctics, mediating kneading time described in homogenizing step two is 24 minutes；
Step 3: grinding: the lotion through mediating by gear pump or is back and forth pumped into colloid mill and is ground；In machinery
Under shearing force, makes the further homogeneous dispersion of the agglomerated masses of colloid or powder, reach the various particles in lotion and be uniformly distributed, grind
It to be placed after mill 28 minutes, the bubble for keeping subtle bubble auto-polymerization big reduces the total surface area of bubble, in favor of under
The progress of one step degassing process；
Step 4: vacuum outgas: by the lotion vacuum outgas after grinding, until vacuum degree is up to -0.096Mpa, time
About 58 minutes；The operation is the molding situation in order to improve lotion, and degassed treated lotion is bright fine and smooth, stripping
It is good；
Step 5: canned packaging: the lotion after degassing can be packed into hose by automatic filling machine after standing, and carry out
Spotweld is or folding tail, the toothpaste after filling sealing are packed by manual or automatic packing machine.
Further, the control of the kneading time is extremely important, and kneading is the important procedure for preparing toothpaste.
Comparative example 1
Comparative example 1 and embodiment 3, the difference is that, by probiotics with etc. the fluorides of parts by weight substitute.
Comparative example 2
Comparative example 2 is substantially the same manner as Example 3, the difference is that, remove pectin and lac resin.As a result it investigates
The crowd of probiotics toothpaste obtained by the present invention will be used, carries out part statistics discovery, use probiotics of the invention
Toothpaste can be effectively reduced dental caries, periodontitis, the disease incidence of bleeding gums, effectively dispel halitosis, canker sore, pure and fresh oral cavity,
Remove oral cavity harmful bacteria, for because caused by teeth brushing way is improper dental part fall, for sensitivity of tooth, there is significant drop
It is low, den tal fluorosis can be significantly improved.
To use toothpaste 6-12 of the present invention months as the period, crowd has different degrees of dental caries, periodontitis from 6-75 one full year of life,
Totally 600 people, each 300 people of men and women are randomly divided into 6 groups, respectively blank group to the user of bleeding gums, canker sore and halitosis:
It is only gargled twice with physiological saline daily morning and evening；Toothpaste with fluoride group: it is brushed teeth twice with commercially available toothpaste with fluoride daily morning and evening；Medium-height grass
Medicine toothpaste group is brushed teeth with commercially available not fluorine-containing Chinese herbal toothpaste twice daily morning and evening；It 3 groups of embodiment, is sent out twice with this daily morning and evening
Bright 3 gained toothpaste of embodiment is brushed teeth；1 group of comparative example: being brushed teeth twice with 1 gained toothpaste of comparative example of the present invention daily morning and evening；Comparison
2 groups of example: being brushed teeth twice with 2 gained toothpaste of comparative example of the present invention daily morning and evening.Avoiding cold and uncooked food stimulates food.
Criterion of therapeutical effect:
Patient carries out curative effect statistics after 15-30 days to the treatment of top method.Criterion of therapeutical effect is as follows:
Cure: symptom disappears, and can be fed with normal occlusion, no discomfort；
Effective: symptom is substantially reduced, and occlusion feed has slight discomfort；
Improve: symptom is alleviated, and further treats, and symptom can disappear；
Invalid: symptom is without improvement, or even aggravates symptom.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, this field is common
Other modifications or equivalent replacement that technical staff makes technical solution of the present invention, without departing from technical solution of the present invention
Spirit and scope, be intended to be within the scope of the claims of the invention.
Claims (6)
1. a kind of probiotics toothpaste, which is characterized in that be composed of the following raw materials in parts by weight: 50-60 parts of silicic acid hydrate, hydroxide
50-60 parts of aluminium, 50-60 parts of lac resin, 20-30 parts of pectin；3-5 parts of moisturizer, 3-5 parts of sodium lauryl sulfonate, carboxymethyl is fine
Tie up plain 5-8 part of sodium, 3-5 parts of Peppermint essential oil, 0.5-2 parts of sweetener, 1-2 parts of chlorophyll, 10-15 parts of Freeze-dry Powder of Probioctics with go from
Sub- water 50-80 parts.
2. a kind of probiotics toothpaste according to claim 1, which is characterized in that the sweetener be etc. parts by weight stevia rebaudianum
Sugar and chrysanthemum flower extract mixing.
3. a kind of probiotics toothpaste according to claim 1, which is characterized in that the composition of the moisturizer are as follows: sorbierite
6-8 parts, 4-5 parts of lecithin, 3-5 parts of chitosan, 2-3 parts of sericin powder, 2-3 parts and deionized water 8-10 parts of marine algae extract；Its
Preparation method is to mix the raw materials of the parts by weight, add it is water-swellable to obtain the final product.
4. the preparation method of -3 probiotics toothpaste according to claim 1, which comprises the steps of:
Step 1: glue: sodium carboxymethylcellulose, lac resin, pectin and sodium lauryl sulfonate are put into size making pot, high speed
It is added with stirring deionized water, stirring to glue homogeneous transparent until no powder, then places a period of time, makes micelle abundant
It is used after swelling；
Step 2: it mediates: glue being squeezed into kneader, silicic acid hydrate, aluminium hydroxide, moisturizer, Peppermint essential oil, sweet taste is added
Agent, chlorophyll and Freeze-dry Powder of Probioctics are mediated uniform；
Step 3: grinding: the lotion through mediating by gear pump or is back and forth pumped into colloid mill and is ground；In mechanical shearing
Under power, makes the further homogeneous dispersion of the agglomerated masses of colloid or powder, reach the various particles in lotion and be uniformly distributed, after grinding
Place a period of time, the bubble for keeping subtle bubble auto-polymerization big；
Step 4: vacuum outgas: by the lotion vacuum outgas after grinding, until vacuum degree reaches -0.096Mpa or more, the time is
50-60 minutes；The operation is the molding situation in order to improve lotion, and degassed treated lotion is bright fine and smooth, and stripping is good；
Step 5: canned packaging: the lotion after degassing can be packed into hose by automatic filling machine after standing, and carry out spot welding
Seam is or folding tail, the toothpaste after filling sealing are packed by manual or automatic packing machine.
5. the preparation method according to claim 4, which is characterized in that kneading time described in step 2 is 20-25 minutes.
6. the preparation method according to claim 4, which is characterized in that placement a period of time described in step 3 is 20-30 points
Clock.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109908072A (en) * | 2019-04-09 | 2019-06-21 | 厦门蓝湾科技有限公司 | A kind of marine polysaccharide toothpaste and preparation method thereof containing profitable probliotics |
| CN112754987A (en) * | 2021-03-06 | 2021-05-07 | 博雅(广州)生物科技研究院有限公司 | Oral care composition containing probiotics and application thereof |
| CN115644301A (en) * | 2022-11-11 | 2023-01-31 | 义乌市嘉奇食品有限公司 | Toothpaste tube packaged pasty chewing gum and preparation method thereof |
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| CN105769745A (en) * | 2014-12-23 | 2016-07-20 | 深圳市绿微康生物工程有限公司 | Probiotics toothpaste composition capable of improving health of oral cavity |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109908072A (en) * | 2019-04-09 | 2019-06-21 | 厦门蓝湾科技有限公司 | A kind of marine polysaccharide toothpaste and preparation method thereof containing profitable probliotics |
| CN109908072B (en) * | 2019-04-09 | 2021-07-16 | 厦门蓝湾科技有限公司 | Marine organism polysaccharide toothpaste containing probiotics and preparation method thereof |
| CN112754987A (en) * | 2021-03-06 | 2021-05-07 | 博雅(广州)生物科技研究院有限公司 | Oral care composition containing probiotics and application thereof |
| CN115644301A (en) * | 2022-11-11 | 2023-01-31 | 义乌市嘉奇食品有限公司 | Toothpaste tube packaged pasty chewing gum and preparation method thereof |
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Application publication date: 20190301 |