CN109394543B - Pharmaceutical bar mark forming machine and using method thereof - Google Patents

Pharmaceutical bar mark forming machine and using method thereof Download PDF

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Publication number
CN109394543B
CN109394543B CN201811169778.XA CN201811169778A CN109394543B CN 109394543 B CN109394543 B CN 109394543B CN 201811169778 A CN201811169778 A CN 201811169778A CN 109394543 B CN109394543 B CN 109394543B
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wall
conveyor belt
roller
groove
transmission device
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CN109394543A (en
Inventor
王志良
李勇义
杨彦熙
胡宇
鲁烨
肖廷文
王志刚
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Youhua Pharmaceutical Leshan Co ltd
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Youhua Pharmaceutical Leshan Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a pharmaceutical note forming machine and a using method thereof in the technical field of forming machines, and the pharmaceutical note forming machine comprises a conveyor belt supporting transmission device, wherein a conveyor belt is sleeved on the outer wall of a transmission wheel in the conveyor belt supporting transmission device, first grooves are uniformly formed in the outer wall of the conveyor belt from front to back, a heating box is screwed at the right part of the top end of the outer wall of a support frame in the conveyor belt supporting transmission device, rollers are pinned at the upper parts of the viewing walls of two groups of support rods, second grooves are uniformly formed in the outer wall of the rollers from front to back, slices are uniformly and fixedly arranged on the circumferences of the outer walls of the rollers and the second grooves, the heating box is started for preheating, and the slice drug mud is extruded, cut and formed by the rollers and then heated by the heating box to form metronidazole.

Description

Pharmaceutical bar mark forming machine and using method thereof
Technical Field
The invention discloses a pharmacy note forming machine and a using method thereof, and particularly relates to the technical field of forming machines.
Background
Metronidazole, mainly used for treating or preventing the above anaerobic bacteria induced system or local infection, such as the anaerobic bacteria infection of abdominal cavity, alimentary canal, female reproductive system, lower respiratory tract, skin and soft tissue, bone and joint, also effective to septicemia, endocarditis, meningeal infection and colitis caused by using antibiotics, and treat tetanus commonly combined with Tetanus Antitoxin (TAT), and also can be used for oral anaerobic bacteria infection, and the precautionary reference of carcinogenic list published by international cancer research organization of world health organization, metronidazole is in 2B carcinogenic list, the existing metronidazole tablet mostly adopts medicinal powder to directly compress, but the medicinal powder directly compresses tablet has larger disintegration and dissolution, the metronidazole tablet is used as a slow medicament when being externally used, when the powder is directly compressed into a metronidazole tablet slow medicament, the disintegration and dissolution are larger, the medicinal property is generated in a short time, in addition, the drug efficacy is wasted.
Disclosure of Invention
The invention aims to provide a pharmaceutical bar forming machine and a using method thereof, aiming at solving the problems that the existing metronidazole tablets proposed in the background technology are mostly formed by directly pressing medicinal powder into tablets, but the medicinal powder has larger disintegration and dissolution rate when the medicinal powder is directly pressed into tablets, the metronidazole tablets are used as slow medicaments when being externally used, and the powder has larger disintegration and dissolution rate when being directly pressed into tablets to form the slow medicaments of the metronidazole tablets, so that the medicinal property is larger in a short time, and the medicinal efficacy is wasted.
In order to achieve the purpose, the invention provides the following technical scheme: a pharmaceutical bar forming machine comprises a conveyor belt supporting transmission device, wherein a conveyor belt is sleeved on the outer wall of a transmission wheel in the conveyor belt supporting transmission device, a first groove is uniformly formed in the outer wall of the conveyor belt from front to back, a heating box is screwed at the right part of the top end of the outer wall of a support frame in the conveyor belt supporting transmission device, a support plate is welded at the left part of the top wall of the support frame in the conveyor belt supporting transmission device, the top wall of the support plate is in contact with the bottom wall of the conveyor belt, support rods are welded at the front and back of the left part of the top wall of the support frame in the conveyor belt supporting transmission device, rollers are connected with the upper parts of the visual walls of the two groups of support rods in a pin mode, a roller motor is fixedly installed on the outer wall of the rear part of the support rods, the output shaft of the roller motor, the even fixed mounting of outer wall circumference of roller and second recess has the section, the section of roller and second recess outer wall contacts with the roof of conveyer belt and first recess respectively, the welding of support frame roof left part has U type support frame among the conveyer belt support transmission, U type support frame is located the right part of bracing piece, the even welding in the past of left wall upper portion to the back of U type support frame has the flitch of scraping, the left end of scraping the flitch contacts with the outer wall of second recess, the welding of right wall upper portion of support frame has finished product buffering frid among the conveyer belt support transmission, the welding of the roof of support frame has rim charge flitch device down among the conveyer belt support transmission, rim charge flitch device is located between U type support frame and the heating cabinet.
Preferably, the cross-section of the slice is tapered.
Preferably, the first and second grooves have the same depth.
Preferably, the heating box is an electric heating box.
Preferably, the roller is a stainless steel hollow roller.
A method of using a pharmaceutical token forming machine, comprising the steps of:
adding water into metronidazole powder, starch and sodium carboxymethylcellulose powder, stirring uniformly to form paste, extruding the medicinal mud into round bar shape by a screw extruder, rolling the round bar-shaped medicinal mud into slice medicinal mud by a compression roller, and starting a heating box for preheating;
start conveyer belt and support transmission and roller motor, place thin slice medicine mud on the conveyer belt, the conveyer belt drives thin slice medicine mud and removes towards the heating cabinet direction, and when thin slice medicine mud got into the roller, thin slice medicine mud was cut apart by roller, conveyer belt, first recess and second recess and is extruded into short slice and rim charge, and short slice medicine mud gets into heating cabinet 3, and moisture in the short slice medicine mud is evaporated and becomes the metronidazole piece.
Compared with the prior art, the invention has the beneficial effects that:
the metronidazole tablet is provided with the first groove, the second groove and the roller, is extruded and sheared into the wet metronidazole tablets by the roller, and is heated and dehydrated into the metronidazole tablets, so that the prepared metronidazole tablet is low in disintegration and dissolution, low in drug property in a short time, and avoids the waste of drug potency; set up flitch device under the rim charge, be convenient for collect rim charge and retrieve and make again, set up the scraper version, avoid moist tablet to bond in the second recess, this device makes into the metronidazole piece through moist metronidazole piece in addition, can not fly upward because of powder and cause the workshop to pollute, also avoid powder extravagant, the invention simple structure, convenient to use effectively reduces medicine disintegration and degree of dissolving out.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a top partial schematic view of the conveyor belt of the present invention;
FIG. 3 is a schematic top view of a roll of the present invention;
FIG. 4 is a schematic cross-sectional elevational view of a roll of the present invention;
fig. 5 is a front cross-sectional partial schematic view of a conveyor belt of the present invention.
In the figure: the device comprises a conveying belt supporting transmission device 1, a conveying belt 2, a first groove 201, a heating box 3, a supporting plate 4, a supporting rod 5, a roller 6, a second groove 601, a 602 slice, a 7U-shaped supporting frame, a scraping plate 8, a finished product buffer groove plate 9 and a leftover material discharging plate 10.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical solution: a pharmaceutical bar forming machine comprises a conveyor belt supporting transmission device 1, wherein a conveyor belt 2 is sleeved on the outer wall of a transmission wheel in the conveyor belt supporting transmission device 1, first grooves 201 are uniformly formed in the outer wall of the conveyor belt 2 from front to back, a heating box 3 is screwed at the right part of the top end of the outer wall of a support frame in the conveyor belt supporting transmission device 1, a support plate 4 is welded at the left part of the top wall of the support frame in the conveyor belt supporting transmission device 1, the top wall of the support plate 4 is contacted with the bottom wall of the conveyor belt 2, support rods 5 are welded at the front part and the back part of the left part of the top wall of the support frame in the conveyor belt supporting transmission device 1, rollers 6 are connected to the upper parts of the visual walls of the two groups of support rods 5 in a pin joint mode, a roller motor is fixedly installed on the outer wall of the rear part, the outer wall of the roller 6 is uniformly provided with second grooves 601 from front to back, the circumferences of the outer wall of the roller 6 and the second grooves 601 are uniformly and fixedly provided with slices 602, the slices of the outer walls of the roller 6 and the second groove 601 are respectively contacted with the top walls of the conveyor belt 2 and the first groove 201, the left part of the top wall of the support frame in the conveyor belt supporting transmission device 1 is welded with a U-shaped support frame 7, the U-shaped support frame 7 is positioned at the right part of the support rod 5, scraping plates 8 are uniformly welded on the upper portion of the left wall of the U-shaped supporting frame 7 from front to back, the left ends of the scraping plates 8 are in contact with the outer wall of the second groove 601, the upper part of the right wall of the support frame in the conveyor belt supporting transmission device 1 is welded with a finished product buffer groove plate 9, and an edge material blanking plate device 10 is welded on the top wall of the support frame in the conveyor belt supporting transmission device 1, and the edge material blanking plate device 10 is positioned between the U-shaped support frame 7 and the heating box 3.
Wherein, the cross section of section 602 is the toper, is convenient for cut off moist metronidazole piece, and the degree of depth of first recess 201 and second recess 601 is the same, and the metronidazole piece thickness of shearing extrusion shaping through first recess 201 and second recess 601 is the same, and heating cabinet 3 is electric heating cabinet, and the programming rate is fast, and heating efficiency is high, and roller 6 is stainless steel hollow roller, and stainless steel intensity is higher, and is corrosion-resistant, sets up to hollow roller, and the quality is light.
A method of using a pharmaceutical token forming machine, comprising the steps of:
adding water into metronidazole powder, starch and sodium carboxymethylcellulose powder, stirring uniformly to form paste, extruding the medicinal mud into round bar shape by a screw extruder, rolling the round bar-shaped medicinal mud into slice medicinal mud by a compression roller, and starting a heating box 3 for preheating;
the conveying belt supporting transmission device 1 and the roller motor are started, the thin slice medicine mud is placed on the conveying belt 2, the conveying belt 2 drives the thin slice medicine mud to move towards the heating box 3, the roller motor drives the roller 6 to rotate anticlockwise, when the thin slice medicine mud enters the roller 6, the thin slice medicine mud is divided and extruded into short slices and rim charge by the roller 6, the conveying belt 2, the first groove 201 and the second groove 601, the central part of the thin slice medicine mud respectively enters the first groove 201 and the second groove 601 to form long slice medicine mud, the long slice medicine mud is cut into short slice medicine mud by the slicing piece 602 along with the transmission of the roller 6 and the conveying belt 2, the short slice medicine mud enters the heating box 3, the thin slice medicine mud at the outer end of the first groove 201 is cut by the roller 6 to form rim charge, the rim charge is blocked by the rim charge plate device 10, the rim charge is uniformly collected, and the rim charge is prevented from entering the heating box 3 to be dehydrated, the leftover bits are integrated and then processed again, and the water in the short tablet medicine mud is evaporated into metronidazole tablets.
The working principle is as follows: the heating box 3 is started to preheat, when the temperature in the heating box 3 rises to the required dehydration temperature, the conveyor belt supporting transmission device 1 and the roller motor are started, the slice medicine mud is placed on the conveyor belt 2, the conveyor belt 2 drives the slice medicine mud to move towards the heating box 3, when the slice medicine mud enters the roller 6, the slice medicine mud is divided and extruded into short slices and rim charge by the roller 6, the first groove 201 and the second groove 601, the central part of the slice medicine mud respectively enters the first groove 201 and the second groove 601 to form long slice medicine mud, the slice 602 cuts the long slice medicine mud into short slice medicine mud along with the transmission of the roller 6 and the conveyor belt 2, when the slice 602, the first groove 201 and the second groove 601 of the roller 6 cut and extrude the slice medicine mud on the conveyor belt 2, the support plate 4 provides upward support force, the metronidazole tablet wetted in the first groove 201 moves towards the heating box 3 along with the conveyor belt 2, the moist metronidazole tablet that is located second recess 601 scrapes flitch 8 and scrapes down and fall on conveyer belt 2, flitch device 10 blocks the rim charge under the rim charge and collects, avoid the rim charge to get into in the heating cabinet 3 by the dehydration, be convenient for remachine after the rim charge integrates, moist metronidazole tablet is followed conveyer belt 2 and is removed towards the heating cabinet 3, moist metronidazole piece gets into the heating cabinet 3, high temperature makes moist metronidazole piece dehydration become the metronidazole piece, then the metronidazole piece leaves through finished product buffer frid 9 along with conveyer belt 2.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A pharmacy note make-up machine, includes conveyer belt support transmission (1), its characterized in that: the outer wall of a driving wheel in the conveyor belt supporting transmission device (1) is sleeved with a conveyor belt (2), the outer wall of the conveyor belt (2) is uniformly provided with a first groove (201) from front to back, the right part of the top end of the outer wall of a support frame in the conveyor belt supporting transmission device (1) is screwed with a heating box (3), the left part of the top wall of the support frame in the conveyor belt supporting transmission device (1) is welded with a support plate (4), the top wall of the support plate (4) is contacted with the bottom wall of the conveyor belt (2), the front part and the back part of the left part of the top wall of the support frame in the conveyor belt supporting transmission device (1) are both welded with support rods (5), the upper parts of the viewing walls of the two groups of support rods (5) are in pin joint connection with a roller (6), the outer wall of the rear part of, the supporting plate (4) is positioned under the roller (6), the outer wall of the roller (6) is uniformly opened with a second groove (601) from the front to the back, slices (602) are uniformly and fixedly installed on the circumferences of the outer wall of the roller (6) and the outer wall of the second groove (601), the slices of the outer wall of the roller (6) and the outer wall of the second groove (601) are respectively contacted with the top walls of the conveyor belt (2) and the first groove (201), a U-shaped supporting frame (7) is welded at the left part of the top wall of the supporting frame in the conveyor belt supporting transmission device (1), the U-shaped supporting frame (7) is positioned at the right part of the supporting rod (5), a scraping plate (8) is uniformly welded at the upper part of the left wall of the U-shaped supporting frame (7) from the front to the back, the left end of the scraping plate (8) is contacted with the outer wall of the second groove (601), a finished product buffer groove plate (9) is welded, the top wall welding of support frame has rim charge flitch device (10) among conveyer belt support transmission (1), rim charge flitch device (10) are located between U type support frame (7) and heating cabinet (3).
2. A pharmaceutical rodding forming machine according to claim 1, wherein: the cross section of the slice (602) is tapered.
3. A pharmaceutical rodding forming machine according to claim 1, wherein: the depth of the first groove (201) is the same as that of the second groove (601).
4. A pharmaceutical rodding forming machine according to claim 1, wherein: the heating box (3) is an electric heating box.
5. A pharmaceutical rodding forming machine according to claim 1, wherein: the roller (6) is a stainless steel hollow roller.
6. A method of using a pharmaceutical baseball forming machine of claim 1, comprising the steps of:
adding water into metronidazole powder, starch and sodium carboxymethylcellulose powder, stirring uniformly to form paste, extruding the medicinal mud into round bar shape by a screw extruder, rolling the round bar-shaped medicinal mud into slice medicinal mud by a compression roller, and starting a heating box (3) for preheating;
start conveyer belt and support transmission (1) and roller motor, place thin slice medicine mud on conveyer belt (2), conveyer belt (2) drive thin slice medicine mud and remove towards heating cabinet (3) direction, when thin slice medicine mud gets into roller (6), thin slice medicine mud is by roller (6), conveyer belt (2), first recess (201) and second recess (601) are cut apart and are extruded into short slice and rim charge, short slice medicine mud gets into heating cabinet (3), moisture in the short slice medicine mud is evaporated and becomes the metronidazole piece.
CN201811169778.XA 2018-10-08 2018-10-08 Pharmaceutical bar mark forming machine and using method thereof Active CN109394543B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201811169778.XA CN109394543B (en) 2018-10-08 2018-10-08 Pharmaceutical bar mark forming machine and using method thereof

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CN109394543B true CN109394543B (en) 2021-05-04

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Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4437823C2 (en) * 1994-10-13 1996-09-05 Schering Ag Feeding device for molding compounds in tabletting machines
JP4380784B2 (en) * 2006-11-15 2009-12-09 新東工業株式会社 Tablet molding method and roll compression molding machine
CN203510761U (en) * 2013-07-25 2014-04-02 重庆帕泰克机械设备制造有限公司 Abrasion resistance type rotating banded extruder
CN203380941U (en) * 2013-08-02 2014-01-08 安徽汇仁堂中药饮片股份有限公司 Cutting device for traditional Chinese medicine decoction pieces
CN205553320U (en) * 2015-10-15 2016-09-07 王树 Special tablet press of medicine
CN205800273U (en) * 2016-05-23 2016-12-14 许昌恒生制药有限公司 A kind of tablet machine for pharmacy
CN207519521U (en) * 2017-11-25 2018-06-22 刘广天 A kind of split cutter formula machine for making noodles with stuffing
CN108379080A (en) * 2018-02-28 2018-08-10 柳州市妇幼保健院 A kind of device of automated production drug paste

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