CN109394543A - A kind of pharmaceutical purpose stick note molding machine and its application method - Google Patents
A kind of pharmaceutical purpose stick note molding machine and its application method Download PDFInfo
- Publication number
- CN109394543A CN109394543A CN201811169778.XA CN201811169778A CN109394543A CN 109394543 A CN109394543 A CN 109394543A CN 201811169778 A CN201811169778 A CN 201811169778A CN 109394543 A CN109394543 A CN 109394543A
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- China
- Prior art keywords
- conveyer belt
- roller
- groove
- wall
- support
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
Abstract
The invention discloses a kind of pharmaceutical purpose stick of molding machine technical field note molding machine and its application methods, transmission device is supported including conveyer belt, the outer wall of driving wheel is socketed with conveyer belt belt in conveyer belt support transmission device, conveyer belt belt outer wall is uniformly provided with the first groove from front to back, support frame outer wall top right part is bolted with heater box in conveyer belt support transmission device, two groups of support rods are mutually connected with roller depending on wall top, the outer wall of roller is uniformly provided with the second groove from front to back, the outer wall even circumferential of roller and the second groove is fixedly installed with slice, starting heater box is preheated, thin slice medicine puree is heated case after being formed by roller extrusion shearing and is heated as Metronidazole Tablet, the configuration of the present invention is simple, it is easy to use, medicine disintegration and dissolution rate is effectively reduced.
Description
Technical field
The invention discloses a kind of pharmaceutical purpose stick note molding machine and its application methods, specially molding machine technical field.
Background technique
Metronidazole is mainly used for system caused by treating or preventing above-mentioned anaerobic bacteria or local infection, such as abdominal cavity, digestion
The anaerobic infection at the positions such as road, female reproductive system, lower respiratory tract, skin and soft tissue, bone and joint, to septicemia, intracardiac
Film is scorching, infection of meninges and also effective using colitis caused by antibiotic, treatment tetanus often with tetanus antitoxin (TAT)
Combination, it may also be used for oral cavity anaerobium infection, the carcinogenic substance inventory that international cancer research institution, the World Health Organization announces are preliminary
Reference is arranged, metronidazole is in 2B class carcinogenic substance inventory, and existing Metronidazole Tablet mostly uses medicinal powder direct pressing in blocks, but medicinal powder
Direct tablet compressing disintegration and dissolution rate are larger, and the Metronidazole Tablet outer used time, direct powder compression did Metronidazole Tablet as slow type medicament
When slow type medicament, disintegration and dissolution rate are larger, and generation pharmacological property is larger in the short time, furthermore the efficacy of a drug are caused to waste.
Summary of the invention
The purpose of the present invention is to provide a kind of pharmaceutical purpose stick note molding machine and its application methods, to solve above-mentioned background skill
The existing Metronidazole Tablet proposed in art mostly uses medicinal powder direct pressing in blocks, but medicinal powder direct tablet compressing disintegration and dissolution rate compared with
Greatly, the Metronidazole Tablet outer used time is as slow type medicament, when direct powder compression does Metronidazole Tablet and delays type medicament, disintegration and dissolution rate
Larger, generation pharmacological property is larger in the short time, furthermore the efficacy of a drug is caused to waste.
To achieve the above object, the invention provides the following technical scheme: a kind of pharmaceutical purpose stick remembers molding machine, including conveyer belt
Transmission device is supported, the outer wall of driving wheel is socketed with conveyer belt belt, the conveyer belt in the conveyer belt support transmission device
Belt outer wall is uniformly provided with the first groove, support frame outer wall top right part spiral shell in the conveyer belt support transmission device from front to back
It is connected to heater box, support frame roof left part is welded with support plate, the top of the support plate in the conveyer belt support transmission device
Wall is contacted with the bottom wall of conveyer belt belt, is welded with branch before and after support frame roof left part in the conveyer belt support transmission device
Strut, support rod described in two groups are mutually connected with roller depending on wall top, and the outer wall of support rod described in rear portion is fixedly installed with roller
Motor, and the rear end of the output shaft of roller motor and roller connects, the support plate is located at the underface of roller, the roller
Outer wall is uniformly provided with the second groove from front to back, and the outer wall even circumferential of the roller and the second groove is fixedly installed with slice,
The slice of the roller and the second groove outer wall is contacted with the roof of conveyer belt belt and the first groove respectively, the conveyer belt branch
Support frame roof left part is welded with U-shaped support frame in support transmission device, and the U-shaped support frame is located at the right part of support rod, the U
Uniform welding has material scraping plate from front to back on the left wall top of type support frame, and the left end of the material scraping plate and the outer wall of the second groove connect
Touching, the conveyer belt support the right wall top of support frame in transmission device to be welded with finished product buffering frid, the conveyer belt support
The roof of support frame is welded with rim charge blanking panel assembly in transmission device, the rim charge blanking panel assembly be located at U-shaped support frame with
Between heater box.
Preferably, the cross section of the slice is tapered.
Preferably, the depth of first groove and the second groove is identical.
Preferably, the heater box is electric heating case.
Preferably, the roller is stainless steel hollow roller drum.
A kind of application method of pharmaceutical purpose stick note molding machine, comprising the following steps:
By metronidazole powder, starch and sodium carboxymethylcellulose powder add water and stir uniformly at pureed after, pass through screw extruder
After medicine puree is squeezed into round bar shape, round bar shape medicine puree is rolled into flakiness medicine puree by pressure roller, starting heater box is preheated；
Start conveyer belt support transmission device and roller motor, thin slice medicine puree is placed on conveyer belt belt, conveyer belt belt
Drive thin slice medicine puree mobile towards heater box direction, when thin slice medicine puree enters roller, thin slice medicine puree is by roller, transmission belt leather
Band, the first groove and the segmentation of the second groove are squeezed into short-movie shape and rim charge, and short-movie shape medicine puree enters heater box 3, in short-movie medicine puree
Moisture be evaporated into as Metronidazole Tablet.
Compared with prior art, the beneficial effects of the present invention are:
The first groove, the second groove and roller is arranged in the present invention, de- at heating after wet Metronidazole Tablet by roller extrusion shearing
Water becomes Metronidazole Tablet, and the Metronidazole Tablet disintegration and dissolution rate that the present invention is fabricated to are smaller, and generation pharmacological property is smaller in the short time,
The efficacy of a drug is avoided to waste；Rim charge blanking panel assembly is set, is remake convenient for collecting edge recycling, scraper version is set, avoids moistening
Tablet is bonded in the second groove, and furthermore the present apparatus is fabricated to Metronidazole Tablet by wet Metronidazole Tablet, will not be flown because of medicinal powder
It raises and workshop is caused to pollute, also medicinal powder is avoided to waste, the configuration of the present invention is simple is easy to use, and medicine disintegration and molten is effectively reduced
Out-degree.
Detailed description of the invention
Fig. 1 is schematic structural view of the invention；
Fig. 2 is that conveyer belt belt of the present invention overlooks partial schematic diagram；
Fig. 3 is roller schematic top plan view of the present invention；
Fig. 4 is that roller of the present invention faces schematic cross-sectional view；
Fig. 5 is that conveyer belt belt of the present invention faces section view partial schematic diagram.
In figure: 1 conveyer belt supports transmission device, 2 conveyer belt belts, 201 first grooves, 3 heater boxes, 4 support plates, 5
Strut, 6 rollers, 601 second grooves, 602 slices, 7 U-shaped support frames, 8 material scraping plates, 9 finished products buffer frid, 10 rim charge blanking plates
Device.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Fig. 1-5 is please referred to, the present invention provides a kind of technical solution: a kind of pharmaceutical purpose stick note molding machine, including conveyer belt branch
Transmission device 1 is supportted, the outer wall of driving wheel is socketed with conveyer belt belt 2, the conveyer belt in the conveyer belt support transmission device 1
2 outer wall of belt is uniformly provided with the first groove 201, support frame outer wall top in the conveyer belt support transmission device 1 from front to back
Right part is bolted with heater box 3, and support frame roof left part is welded with support plate 4, the branch in the conveyer belt support transmission device 1
The roof of fagging 4 is contacted with the bottom wall of conveyer belt belt 2, in the conveyer belt support transmission device 1 before support frame roof left part
It is welded with support rod 5 afterwards, support rod 5 described in two groups is mutually connected with roller 6 depending on wall top, outside support rod 5 described in rear portion
Wall is fixedly installed with roller motor, and the output shaft of roller motor is connect with the rear end of roller 6, and the support plate 4 is located at roller 6
Underface, the outer wall of the roller 6 is uniformly provided with the second groove 601 from front to back, the roller 6 and the second groove 601
Outer wall even circumferential is fixedly installed with slice 602, the slice of 601 outer wall of the roller 6 and the second groove respectively with transmission belt leather
With 2 and first groove 201 roof contact, support frame roof left part is welded with U-shaped branch in conveyer belt support transmission device 1
Support 7, the U-shaped support frame 7 are located at the right part of support rod 5, and the left wall top of the U-shaped support frame 7 is uniformly welded from front to back
It is connected to material scraping plate 8, the left end of the material scraping plate 8 is contacted with the outer wall of the second groove 601, and the conveyer belt supports transmission device 1
The right wall top of middle support frame is welded with finished product buffering frid 9, the roof weldering of support frame in the conveyer belt support transmission device 1
It is connected to rim charge blanking panel assembly 10, the rim charge blanking panel assembly 10 is between U-shaped support frame 7 and heater box 3.
Wherein, be sliced 602 cross section it is tapered, convenient for cutting off wet Metronidazole Tablet, the first groove 201 and the second groove
601 depth is identical, identical with the molding Metronidazole Tablet thickness of 601 shear extrusion of the second groove by the first groove 201, heating
Case 3 is electric heating case, and heating rate is fast, and heating efficiency is high, and roller 6 is stainless steel hollow roller drum, and stainless hardness of steel is higher, corrosion resistant
Erosion, is set as hollow roller drum, light weight.
A kind of application method of pharmaceutical purpose stick note molding machine, comprising the following steps:
By metronidazole powder, starch and sodium carboxymethylcellulose powder add water and stir uniformly at pureed after, pass through screw extruder
After medicine puree is squeezed into round bar shape, round bar shape medicine puree is rolled into flakiness medicine puree by pressure roller, starting heater box 3 carries out pre-
Heat；
Start conveyer belt support transmission device 1 and roller motor, thin slice medicine puree is placed on conveyer belt belt 2, transmits belt leather
Band 2 drives thin slice medicine puree mobile towards 3 direction of heater box, and roller motor drives roller 6 in rotating counterclockwise, when thin slice medicine puree into
When entering roller 6, thin slice medicine puree is squeezed into short-movie by the segmentation of roller 6, conveyer belt belt 2, the first groove 201 and the second groove 601
Shape and rim charge, thin slice medicine puree central part respectively enter the first groove 201 and the second groove 601, form long sheet medicine puree, with
Long sheet medicine puree is cut into short-movie shape medicine puree by the transmission of roller 6 and conveyer belt belt 2, slice 602, and short-movie shape medicine puree, which enters, to be added
Hot tank 3, the thin slice medicine puree positioned at 201 outer end of the first groove form rim charge by the cutting of roller 6, and rim charge is by rim charge blanking panel assembly 10
Stopping, rim charge is uniformly collected, avoids rim charge from entering in heater box 3 and be dehydrated, convenient for being re-worked after rim charge integration, short-movie medicine
Moisture in mud is evaporated into as Metronidazole Tablet.
Working principle: starting heater box 3 is preheated, when temperature rises to required dehydration temperaturre in heater box 3, starting
Conveyer belt supports transmission device 1 and roller motor, thin slice medicine puree is placed on conveyer belt belt 2, conveyer belt belt 2 drives thin
Piece medicine puree is mobile towards 3 direction of heater box, and when thin slice medicine puree enters roller 6, thin slice medicine puree is by roller 6,201 and of the first groove
The segmentation of second groove 601 is squeezed into short-movie shape and rim charge, and it is recessed that thin slice medicine puree central part respectively enters the first groove 201 and second
Slot 601 forms long sheet medicine puree, and with the transmission of roller 6 and conveyer belt belt 2, long sheet medicine puree is cut into short by slice 602
Sheet medicine puree carries out the thin slice medicine puree on conveyer belt belt 2 in slice 602,6 first groove 201 of roller and the second groove 601
When cutting squeezes, support plate 4 provides upward support force, moistens metronidazole tablet with conveyer belt belt 2 positioned at the first groove 201
It is mobile towards 3 direction of heater box, it is scraped positioned at the wet metronidazole tablet material scraping plate 8 of the second groove 601 and falls in conveyer belt belt 2
On, rim charge is stopped to collect by rim charge blanking panel assembly 10, is avoided rim charge from entering in heater box 3 and is dehydrated, after rim charge integration
It re-works, wet metronidazole tablet follows conveyer belt belt 2 mobile towards heater box 3, and wet Metronidazole Tablet enters heater box
3, high temperature makes wet Metronidazole Tablet be dehydrated into Metronidazole Tablet, then Metronidazole Tablet with conveyer belt belt 2 it is slow by finished product
Sloted punched plate 9 leaves.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (6)
1. a kind of pharmaceutical purpose stick remembers molding machine, including conveyer belt support transmission device (1), it is characterised in that: the conveyer belt branch
The outer wall of driving wheel is socketed with conveyer belt belt (2) in support transmission device (1), and conveyer belt belt (2) outer wall is from front to back
It is uniformly provided with the first groove (201), support frame outer wall top right part is bolted with heating in conveyer belt support transmission device (1)
Case (3), the conveyer belt support support frame roof left part in transmission device (1) to be welded with support plate (4), the support plate (4)
Roof contacted with the bottom wall of conveyer belt belt (2), in conveyer belt support transmission device (1) before and after support frame roof left part
It is welded with support rod (5), support rod described in two groups (5) is mutually connected with roller (6) depending on wall top, support rod described in rear portion
(5) outer wall is fixedly installed with roller motor, and the output shaft of roller motor is connect with the rear end of roller (6), the support plate
(4) it is located at the underface of roller (6), the outer wall of the roller (6) is uniformly provided with the second groove (601), the roller from front to back
The outer wall even circumferential of cylinder (6) and the second groove (601) is fixedly installed with slice (602), the roller (6) and the second groove
(601) slice of outer wall is contacted with the roof of conveyer belt belt (2) and the first groove (201) respectively, and the conveyer belt support passes
Support frame roof left part is welded with U-shaped support frame (7) in dynamic device (1), and the U-shaped support frame (7) is located at the right side of support rod (5)
Portion, uniform welding has material scraping plate (8) from front to back on the left wall top of the U-shaped support frame (7), the left end of the material scraping plate (8)
It is contacted with the outer wall of the second groove (601), the right wall top of support frame is welded with into conveyer belt support transmission device (1)
Product buffer frid (9), and the roof of support frame is welded with rim charge blanking panel assembly in conveyer belt support transmission device (1)
(10), the rim charge blanking panel assembly (10) is between U-shaped support frame (7) and heater box (3).
2. a kind of pharmaceutical purpose stick according to claim 1 remembers molding machine, it is characterised in that: described to be sliced the transversal of (602)
Face is tapered.
3. a kind of pharmaceutical purpose stick according to claim 1 remembers molding machine, it is characterised in that: first groove (201) and
The depth of second groove (601) is identical.
4. a kind of pharmaceutical purpose stick according to claim 1 remembers molding machine, it is characterised in that: the heater box (3) is that electricity adds
Hot tank.
5. a kind of pharmaceutical purpose stick according to claim 1 remembers molding machine, it is characterised in that: the roller (6) is stainless steel
Hollow roller drum.
6. a kind of application method of pharmaceutical purpose stick note molding machine, comprising the following steps:
By metronidazole powder, starch and sodium carboxymethylcellulose powder add water and stir uniformly at pureed after, pass through screw extruder
After medicine puree is squeezed into round bar shape, round bar shape medicine puree is rolled into flakiness medicine puree by pressure roller, starting heater box (3) carries out pre-
Heat；
Start conveyer belt support transmission device (1) and roller motor, thin slice medicine puree is placed on conveyer belt belt (2), transmits
Band belt (2) drives thin slice medicine puree mobile towards heater box (3) direction, when thin slice medicine puree enters roller (6), thin slice medicine puree quilt
Roller (6), conveyer belt belt (2), the first groove (201) and the second groove (601) segmentation are squeezed into short-movie shape and rim charge, short-movie
Shape medicine puree enters heater box (3), and the moisture in short-movie medicine puree is evaporated into as Metronidazole Tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811169778.XA CN109394543B (en) | 2018-10-08 | 2018-10-08 | Pharmaceutical bar mark forming machine and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811169778.XA CN109394543B (en) | 2018-10-08 | 2018-10-08 | Pharmaceutical bar mark forming machine and using method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109394543A true CN109394543A (en) | 2019-03-01 |
| CN109394543B CN109394543B (en) | 2021-05-04 |
Family
ID=65466843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811169778.XA Active CN109394543B (en) | 2018-10-08 | 2018-10-08 | Pharmaceutical bar mark forming machine and using method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109394543B (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4437823A1 (en) * | 1994-10-13 | 1996-04-18 | Schering Ag | Feed system for tablet press |
| CN101583483A (en) * | 2006-11-15 | 2009-11-18 | 新东工业株式会社 | Tabletting method and roll compression molding machine for the method |
| CN203380941U (en) * | 2013-08-02 | 2014-01-08 | 安徽汇仁堂中药饮片股份有限公司 | Cutting device for traditional Chinese medicine decoction pieces |
| CN203510761U (en) * | 2013-07-25 | 2014-04-02 | 重庆帕泰克机械设备制造有限公司 | Abrasion resistance type rotating banded extruder |
| CN205553320U (en) * | 2015-10-15 | 2016-09-07 | 王树 | Special tablet press of medicine |
| CN205800273U (en) * | 2016-05-23 | 2016-12-14 | 许昌恒生制药有限公司 | A kind of tablet machine for pharmacy |
| CN207519521U (en) * | 2017-11-25 | 2018-06-22 | 刘广天 | A kind of split cutter formula machine for making noodles with stuffing |
| CN108379080A (en) * | 2018-02-28 | 2018-08-10 | 柳州市妇幼保健院 | A kind of device of automated production drug paste |
-
2018
- 2018-10-08 CN CN201811169778.XA patent/CN109394543B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4437823A1 (en) * | 1994-10-13 | 1996-04-18 | Schering Ag | Feed system for tablet press |
| CN101583483A (en) * | 2006-11-15 | 2009-11-18 | 新东工业株式会社 | Tabletting method and roll compression molding machine for the method |
| CN203510761U (en) * | 2013-07-25 | 2014-04-02 | 重庆帕泰克机械设备制造有限公司 | Abrasion resistance type rotating banded extruder |
| CN203380941U (en) * | 2013-08-02 | 2014-01-08 | 安徽汇仁堂中药饮片股份有限公司 | Cutting device for traditional Chinese medicine decoction pieces |
| CN205553320U (en) * | 2015-10-15 | 2016-09-07 | 王树 | Special tablet press of medicine |
| CN205800273U (en) * | 2016-05-23 | 2016-12-14 | 许昌恒生制药有限公司 | A kind of tablet machine for pharmacy |
| CN207519521U (en) * | 2017-11-25 | 2018-06-22 | 刘广天 | A kind of split cutter formula machine for making noodles with stuffing |
| CN108379080A (en) * | 2018-02-28 | 2018-08-10 | 柳州市妇幼保健院 | A kind of device of automated production drug paste |
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| Publication number | Publication date |
|---|---|
| CN109394543B (en) | 2021-05-04 |
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