CN109392910A - A kind of bactericidal composition containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate - Google Patents

A kind of bactericidal composition containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate Download PDF

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Publication number
CN109392910A
CN109392910A CN201710694138.XA CN201710694138A CN109392910A CN 109392910 A CN109392910 A CN 109392910A CN 201710694138 A CN201710694138 A CN 201710694138A CN 109392910 A CN109392910 A CN 109392910A
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copper
hydroxyquinolinate
fluorine ether
ether bacterium
bactericidal composition
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CN201710694138.XA
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葛家成
司国栋
白复芹
刘晓晨
王金凤
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Hailir Pesticides and Chemicals Group Co Ltd
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Hailir Pesticides and Chemicals Group Co Ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16—Heavy metals; Compounds thereof
    • A01N59/20—Copper

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The present invention relates to a kind of bactericidal composition containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate, effective component is fluorine ether bacterium amide and copper 8-hydroxyquinolinate binary built.Wherein the mass ratio of fluorine ether bacterium amide and copper 8-hydroxyquinolinate is 1~25: 25~1, the mass parts ratio 1%~80% of effective component fluorine ether bacterium amide and copper 8-hydroxyquinolinate in preparation, remaining is the auxiliary element for allowing to use and receive in pesticide, and the dosage form of bactericidal composition of the present invention is missible oil, suspending agent, wettable powder, aqua, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations.It is mainly used for preventing and treating the diseases such as cucumber, downy mildew of garpe, gray mold.

Description

A kind of bactericidal composition containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate
Technical field
The present invention relates to technical field of pesticide compounding, more particularly to a kind of sterilization containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate Composition.
Background technique
Fluorine ether bacterium amide is a kind of new formamide class fungicide, to the vegetative propagation process of germ, permeability of cell membrane There is obvious inhibiting effect with tricarboxylic acid cycle.
Copper 8-hydroxyquinolinate (oxine-copper, No. CAS: 10380-28-6) is to clamp together state organic copper fungicide, for preventing and treating apple The pesticide composition of fruit tree ring spot etc..Have the characteristics that efficient, wide spectrum, safety, low toxicity, low-residual, to fungi, bacterial disease All there is excellent control efficiency.The product mode of action is unique, forms fine and close protective film in crop surface, kills cause of disease in film Bacterium.Inside pathogen, inhibit the activity and conduction of the main conduction object of pathogen, to kill pathogen.It is mainly used for preventing Control downy mildew, anthracnose and bacterial angular leaf spot.
Application chemical agent is the most effective means of controlling plant diseases.But it applies to long-term continuous high dose single Chemical bactericide, the problems such as be easy to causeing the residual of medicament, environmental pollution and drug-resistant fungi to develop.Reasonable chemistry It is bactericide compounded or it is mixed have expand fungicidal spectrum, improve control efficiency, extend the optimum period for applying fertilizer, reduce dosage, reduce phytotoxicity, The positive features such as residual, the generation for delaying drug resistance of fungi and development are reduced, bactericide compounded is to solve above-mentioned ask One of the maximally efficient method of topic.It is constantly soaring to develop new product fungicide price, and in contrast, exploitation with research efficiently, Low toxicity, low-residual compounding and mixture have small investment, the lead time is short and is paid attention to both at home and abroad, one after another increasing develop Dynamics.We filter out fluorine ether bacterium amide and are compounded with copper 8-hydroxyquinolinate based on the indoor screening and field trials, have bright Aobvious synergistic effect.And people there is no to report at present with the bactericidal composition of copper 8-hydroxyquinolinate compounded and application about fluorine ether bacterium amide It crosses.
Summary of the invention
Based on the above circumstances, it is an object of that present invention to provide a kind of new and effective pesticide sterilizing composites.It is mainly used for Prevent and treat the diseases such as cucumber, downy mildew of garpe, gray mold.
The technical solution of the present invention is achieved by the following measures:
A kind of bactericidal composition containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate, the effective component fluorine ether bacterium acyl of the bactericidal composition Amine is compounded with copper 8-hydroxyquinolinate two-spot, remaining is auxiliary element.Wherein effective component fluorine ether bacterium amide and quinoline in the bactericidal composition The mass ratio of quinoline copper is 1~25: 25~1, and the bactericidal composition of the present invention is through toxicity test experimental verification, fluorine ether bacterium amide When mass ratio with copper 8-hydroxyquinolinate is 1~10: 10~1, synergistic effect is preferable.
The formulations of pesticide that the bactericidal composition of the present invention can be prepared are missible oil, suspending agent, wettable powder, water Agent, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations.Wherein effective component fluorine ether bacterium amide and copper 8-hydroxyquinolinate exist Gross mass in preparation accounts for the 1%~80% of the entire quality of the pharmaceutical preparations, wherein toxicity and residues reach preferable when accounting for 10%~60% Balance, cost is relatively low.
The specific embodiment for the formulations of pesticide that bactericidal composition of the present invention is configured to is as follows:
The bactericidal composition is cream preparation, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Copper 8-hydroxyquinolinate 1 ~25 parts；10~30 parts of conventional emulsifier；20~50 parts of Conventional solvents；1~5 part of conventional synergist.The cream preparation it is specific Production stage is to add emulsifier, synergy after being first completely dissolved in effective component fluorine ether bacterium amide and copper 8-hydroxyquinolinate addition solvent Agent is filling after mixing evenly at homogeneous and transparent oily liquids, can the missible oil preparation made into the composition of the present invention.
The bactericidal composition is suspending agent, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Copper 8-hydroxyquinolinate 1~ 25 parts；5~20 parts of dispersing agent；1~5 part of antifreezing agent；0.1~2 part of thickener；0.1~0.8 part of defoaming agent；Penetrating agent 0~10 Part；0.1~5 part of pH adjusting agent；Water, surplus.The specific production stage of the suspending agent is first to mix other auxiliary agents, through high speed Shear-mixed is uniform, and effective component fluorine ether bacterium amide and copper 8-hydroxyquinolinate, abrading-ball 2~3 hours in ball crusher, which is added, keeps a diameter equal In 5mm hereinafter, can be made into the aqueous suspension formulations of the present composition.
The bactericidal composition is wettable powder, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Quinoline 1~25 part of copper；3~10 parts of dispersing agent；1~5 part of wetting agent；Filler, surplus.The specific production stage of the wettable powder are as follows: Effective component fluorine ether bacterium amide is mixed with copper 8-hydroxyquinolinate and dispersing agent, wetting agent and filler by above-mentioned formula, in a stirring kettle Uniform stirring is being uniformly mixed after airslide disintegrating mill, that is, can be made into the wettable powder of the present composition.
The bactericidal composition is water dispersible granules, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Quinoline 1~25 part of copper；3~10 parts of dispersing agent；1~10 part of wetting agent；1~5 part of disintegrating agent；Filler, surplus.The water dispersible granules Specific production stage are as follows: by above-mentioned formula by effective component fluorine ether bacterium amide and copper 8-hydroxyquinolinate and dispersing agent, wetting agent, disintegrating agent with And filler is uniformly mixed, and is crushed with micro jet, through mediating, is then added in fluidized-bed granulation dryer and is made Through sampling analysis after grain, dry, screening, that is, it can be made into the water dispersible granules of the present composition.
The bactericidal composition is aqueous emulsion, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Copper 8-hydroxyquinolinate 1~ 25 parts；3~30 parts of emulsifier；5~15 parts of solvent；2~15 parts of stabilizer；1~5 part of antifreezing agent；0.1~8 part of defoaming agent；Increase Thick dose 0.2~2 part；Water, surplus.The specific production stage of the aqueous emulsion are as follows: first by fluorine ether bacterium amide and copper 8-hydroxyquinolinate, solvent and Emulsifier, cosolvent are added together, and make to be dissolved into uniform oily phase；By part water, antifreeze, the others agriculture such as antimicrobial Medicine auxiliary agent mixes into uniform water phase；The oil phase is added to the aqueous phase while being stirred in the reactor at high speed, slowly plus water Until reaching phase inversion point, open cutter and carry out high speed shear, and remaining water is added, shearing about half an hour, forms oil-in-water The aqueous emulsion of type can be made into the aqueous emulsion of the present composition.
The bactericidal composition is microemulsion, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Copper 8-hydroxyquinolinate 1~ 25 parts；10~30 parts of emulsifier, 1~8 part of antifreezing agent, 0.5~10 part of stabilizer, 20~50 parts of Conventional solvents cosolvent.By fluorine Ether bacterium amide and copper 8-hydroxyquinolinate are completely dissolved with cosolvent, add the other compositions such as emulsifier, antifreezing agent stabilizer, uniformly mixed It closes, is eventually adding water, microemulsion can be made into after being sufficiently stirred.
The bactericidal composition is granule, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Copper 8-hydroxyquinolinate 1~ 25 parts；1~10 part of wetting dispersing agent；0.1~5 part of thickener；0.1~5 part of defoaming agent；Castor oil, surplus are supplied.It will be effective Ingredient fluorine ether bacterium amide is mixed according to the formula with each components such as copper 8-hydroxyquinolinate, dispersing agent, stabilizer, defoaming agent and solvents, puts Enter in sand milling kettle after grinding, is sent into mixing in mixer for well-distribution and gets product.
The bactericidal composition is aqua, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Copper 8-hydroxyquinolinate 1~25 Part；0.1~30 part of wetting dispersing agent；2~8 parts of antifreezing agent；0.1~1 part of defoaming agent；0.1~3 part of thickener；Spreader-sticker 5~15 Part；Water, surplus are supplied.Effective component fluorine ether bacterium amide is completely dissolved with copper 8-hydroxyquinolinate, with cosolvent, dispersing agent is added, prevents Freeze the other compositions such as agent, defoaming agent, uniformly mixes, be eventually adding water, after being sufficiently stirred, finished product can be obtained.
The bactericidal composition is microcapsule formulations, the mass fraction of component are as follows: 1~25 part of amide of fluorine ether bacterium；Copper 8-hydroxyquinolinate 1 ~25 parts；5~20 parts of urea；5~20 parts of formaldehyde；5~20 parts of emulsifying dispersant；1~5 part of antifreezing agent；Thickener 0.1~2 Part；0.1~0.8 part of defoaming agent；Water, surplus.Urea and the formaldehyde (amount of substance are added in three-necked flask with a mixing device Than being about l:1.5~2.0), the pH value for adjusting solution with sodium hydroxide solution then heats to 70~80 DEG C to 8~9 or so, Reaction obtains stable urea resin prepolymer.A certain amount of fluorine ether bacterium amide and copper 8-hydroxyquinolinate is taken to be dissolved in hexamethylene, and molten Emulsifying dispersant is added in liquid, with being vigorously stirred, is made into and stablizes cream by the O/W type of water phase of aqueous solution containing emulsified dispersant Liquid.Above-mentioned urea resin prepolymer is added in lotion, adjusts pH value, polymerization occurs under acid catalyzed conditions, makes oil Phase substance is wrapped, and forms microcapsule granule.Slowly heating, solidification, temperature control is at 40~50 DEG C, curing time 1h. Suitable auxiliary agent is added in selection, can obtain stable microcapsules.
Wherein above-described emulsifier is selected from calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, alkyl phenol polyoxy Ethylene ether sulfosuccinates, styrylphenol polyoxyethylene ether, nonylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, Aliphatic acid polyethenoxy base ester, any one of polyoxyethylene aliphatic alcohol ether or more than one a mixture of arbitrary proportions.
The solvent is xylene or biodiesel, toluene, diesel oil, methanol, ethyl alcohol, n-butanol, isopropanol, rosin-based Vegetable oil code name be ND-45, solvent naphtha, dimethylformamide, dimethyl sulfoxide, one of water equal solvent or more than one It anticipates than the mixture of composition.
It is LG-3, GY-D1252, GY-D1256, SNWGF-01, lignin that the dispersing agent, which is selected from polycarboxylate code name, Sulfonate code name is 201107,201108, alkylphenol polyoxyethylene ether methyl ether condensation sulfate, alkylsulfonate calcium salt, naphthalene Sulfonic formaldehyde condensation compound sodium salt, alkyl phenol polyoxyethylene ether, polyoxyethylene carboxylate, aliphatic amine polyoxyethylene ether, glycerolipid One or more of fat acid ester polyoxyethylene ether.
The wetting agent is selected from lauryl sodium sulfate, calcium dodecyl benzene sulfonate, and Nekal BX moistens bleeding agent F, Alkylbenzene sulfonate polyoxyethylene triphen phosphenylic acid salt dimly, spaonin powder, silkworm excrement, one of spaonin powder or a variety of.
The disintegrating agent is selected from bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, in sodium bicarbonate It is one or more.
The thickener be selected from xanthan gum, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, aluminum magnesium silicate, It is one or more in polyvinyl alcohol.
The stabilizer is selected from sodium citrate, one of resorcinol.
The antifreezing agent is selected from ethylene glycol, propylene glycol, one of glycerine or a variety of.
The defoaming agent is selected from silicone oil, silicone compound, C10-20Saturated fat acids compound, C8-10Fatty alcohol It is one or more.
The filler is selected from kaolin, diatomite, bentonite, attapulgite, white carbon black, starch, in precipitated calcium carbonate It is one or more.
The present invention has apparent synergistic effect using fluorine ether bacterium amide and copper 8-hydroxyquinolinate as the composite bactericide of effective component, prolongs The generation of slow key drug resistance, and production and application costs are reduced, it is mainly used for preventing and treating cucumber, downy mildew of garpe, ash The diseases such as mildew.
Specific embodiment
To make technical solution of the present invention, purpose and advantage are more clearly understood, present invention following specific embodiments It is illustrated, but the present invention is not limited to these examples.Effect experiment of the invention uses indoor biometrics and field trial phase In conjunction with mode, unless otherwise instructed, ratio mentioned below is all mass parts ratio.
Embodiment: fluorine ether bacterium amide and copper 8-hydroxyquinolinate virulence experiment with different proportions.
1.1 reagent agent
85% copper 8-hydroxyquinolinate raw medicine, 90% fluorine ether bacterium amide raw medicine, above-mentioned raw medicine is by extra large Lear medicine company limited liability company Research and development department provides.
1.2 test targets
Fluorine ether bacterium amide was never applied from Shandong Shouguang acquired with the cucumber potting of copper 8-hydroxyquinolinate and same type and separated, supplied Try cucumber variety: Chang Chun Mi Ci.
1.3 test method
1.3.1 medicament is prepared
Acetone solution raw medicine is first used, suitable two raw medicine is made by several different ratios according to the result of preliminary experiment, It is diluted each of the treatment into several concentration gradients for use with acetone again.
By the cultivation of susceptible cucumber variety Chang Chun Mi Ci in pot for growing seedlings, it is placed in a greenhouse culture, plant grows to three to four leaves After phase, the blade of identical leaf age is acquired, the culture and measurement for gray mold of cucumber germ.
1.3.2 the culture of gray mold of cucumber germ and the preparation of spore suspension
Gray mold of cucumber germ is cultivated under conditions of 20 DEG C, 12h alternation of light and darkness using plants method, and every 30d turns generation Culture 1 time.With the conidium on sterile water elution incidence of leaf when inoculation, being configured to spore concentration is l × 106A/mL's Suspension.
1.3.3 strains tested sensitivity testing
Toxicity test is carried out using leaf dish moisturizing method.The blade of acquisition is first prepared into the leaf dish that diameter is 1.5cm, at random It mixes, is respectively placed in configured series of concentrations medical fluid and impregnates lh, 25 leaf dishes of each concentration are tested with the place of not adding medicine Reason is blank control, and after immersion, leaf is face-up placed on the blotting paper of identical liquor strength wetting, in leaf dish Medical fluid blot, by prepared spore suspension l0L be inoculated in leaf dish center, after being placed at room temperature for 5min, be placed in 20 DEG C, 12h It is cultivated under conditions of alternation of light and darkness, the onset area in leaf dish is measured after 10d, calculates EC50。
The toxicity test of mixture is carried out according to mixed ratio with single agent virulence determination method.
The EC that will be managed everywhere in measurement according to Sun Yunpei's Method50Value is converted into practical mixed toxicity index (ATI)；According to mixture Proportion, obtain theoretical mixed toxicity index (TTI), the co-toxicity coefficient (CTC) of mixture be calculated according to the following formula.
Single dose toxicity index=(standard agent EC50/ reagent agent EC50)*100；
ATI=(standard agent EC50/ reagent agent (mixed) EC50)*100；
Content of the toxicity index X B of content (the %)+B of the toxicity index X A of TI I=A in using in using with (%)；
CTC=(ATI/TTI) * 100；
If co-toxicity coefficient is big by 120, show there is synergistic effect；If being significantly lower than 100 (80 or less), it is shown to be antagonism； Between 100~120, it is shown to be summation action.
2 toxicity test results
1 copper 8-hydroxyquinolinate of table is with fluorine ether bacterium amide to the toxicity test of gray mold of cucumber
As can be seen from the table, the test result of different proportion proportion shows to dilute equal table respectively in effective component ratio Reveal stronger synergistic effect, wherein with fluorine ether bacterium amide and copper 8-hydroxyquinolinate for 1:10~10:1 when synergistic effect is good suggests pair Suitable proportion 1:10~10:1 or so mixture preparation carries out further field control effectiveness test, to evaluate its field practical application Effect.
3. field trial prevents and treats cucumber downy mildew
3.1 test method
Twice, equivalent clear water is sprayed in check plot for application altogether for test.When making up a prescription, first with a small amount of water by medicament after completely dissolution, then Suitable quantity of water is added and carries out whole plant spray treatment, even spraying.It is all made of power driven sprayer when spray, operating pressure is 0.3~ 0.4MPa, spray head aperture 1.3mm.Cell spouting liquid is 40~50kg/667m2, it is continuous to be administered twice, interval 10 days, by medicine Liquid uniformly sprays application to crop complete stool.
3.2 investigation method
It is experimental field located at Shandong Shouguang, selecting natually morbid plastic tent cucumber is experimental field, and soil fertility is medium, irrigation and drainage side Just.Using double line sampling method, every cell takes at 5 points, and every is looked into 5 caves, and 2 blades in every plant of fixed middle part carry out fixed point inspection when investigation It looks into.
It is classified according to cucumber downy mildew grade scale, record total strain number, diseased plant number, severity, calculating diseased plant rate, Disease index and preventive effect.
Cucumber downy mildew grade scale is
0 grade: blade disease-free spot；
1 grade: lesion area accounts for 5% or less entire leaf area；
3 grades: lesion area accounts for the 6%~10% of entire leaf area；
5 grades: lesion area accounts for the 11%~25% of entire leaf area；
7 grades: lesion area accounts for the 26%~50% of entire leaf area；
9 grades: lesion area accounts for 50% or more of entire leaf area.
Test is investigated 3 times altogether, i.e. investigation of premedication disease index, preventive effect investigation in 10 days after the 1st medicine, after 2 medicines 10 days and Preventive effect investigation in 20 days.
3.3 phytotoxicity investigation
Whether continuous 7d range estimation medicament has phytotoxicity to crop after application.
3.4 drug effect calculation methods
Sick leaf rate (the %)=disease number of sheets/investigation total number of sheets × 100
Disease index=∑ (the disease numbers of sheets at different levels × opposite value of series)/(investigation total number of sheets × 9) × 100
Control efficiency (%)=(1- (disease index after disease index × treatment region medicine before blank district medicine)/(blank pair According to disease index before disease index after area's medicine × treatment region medicine)) × 100.
3.5 field control effectiveness test result of the tests
The experiment effect of each test medicine of table 2 prevention and treatment cucumber downy mildew
As shown in Table 2, the effect that 54% fluorine ether bacterium amide combines prevention and treatment cucumber downy mildew with 1: 2 mixture of copper 8-hydroxyquinolinate is relatively more aobvious It writes, the significant effect of compound preparation is better than two kinds of single doses, not only significantly improves the control efficiency for downy mildew, but also into one Step extends its lasting period, and generates under continuous phytotoxicity in 7 days observation without phytotoxicity.
Interpretation of result:
In conclusion the present invention contains the bactericidal composition of fluorine ether bacterium amide and copper 8-hydroxyquinolinate, to cucumber downy mildew, gray mold There is good control efficiency, and it is safe to Target crops.Compound preparation not only increases preventive effect, and expands fungicidal spectrum, Use scope is widened, cost is reduced, plays the role of that a medicine is simultaneous to be controlled to multiple diseases, mitigates manpower and material resources, improves productivity effect. So the invention of this compound preparation has a very important significance society with popularization.

Claims (4)

1. a kind of bactericidal composition containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate, it is characterised in that: the bactericidal composition it is effective at It is divided into fluorine ether bacterium amide and copper 8-hydroxyquinolinate binary built, remaining is auxiliary element, wherein effective component fluorine ether bacterium amide and copper 8-hydroxyquinolinate Mass ratio be 1~25: 25~1.
2. bactericidal composition according to claim 1, it is characterised in that: fluorine ether bacterium amide and copper 8-hydroxyquinolinate in the formulation total Weight accounts for the 1%~80% of the entire quality of the pharmaceutical preparations.
3. bactericidal composition according to claim 2, it is characterised in that: fluorine ether bacterium amide and copper 8-hydroxyquinolinate in the formulation total Weight accounts for the 5%~60% of the entire quality of the pharmaceutical preparations.
4. bactericidal composition according to claim 1 or 2 or 3, it is characterised in that: the dosage form of the bactericidal composition is cream Oil, suspending agent, aqua, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations.
CN201710694138.XA 2017-08-15 2017-08-15 A kind of bactericidal composition containing fluorine ether bacterium amide and copper 8-hydroxyquinolinate Pending CN109392910A (en)

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Application publication date: 20190301