CN105394048A - Bactericidal composition containing prothioconazole and efficient metalaxyl-M - Google Patents
Bactericidal composition containing prothioconazole and efficient metalaxyl-M Download PDFInfo
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- CN105394048A CN105394048A CN201510963642.6A CN201510963642A CN105394048A CN 105394048 A CN105394048 A CN 105394048A CN 201510963642 A CN201510963642 A CN 201510963642A CN 105394048 A CN105394048 A CN 105394048A
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- prothioconazoles
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
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Abstract
A bactericidal composition containing prothioconazole and efficient metalaxyl-M is compounded from the active ingredients of prothioconazole and efficient mefenoxam, and the balance of auxiliary components. The pesticide composition comprises the active ingredients prothioconazole and efficient metalaxyl-M in the weight ratio of 1-50:50-1. The active ingredients prothioconazole and metalaxyl-M account for 1-80 wt% of the preparation, and the balance are auxiliary components acceptable in pesticide. The dosage form of the pesticide composition can be missible oil, suspension, wettable powder, water dispersible granule, emulsion in water, micro-emulsion, granules, micro-capsule and water aqua. The composition effectively controls gray mold, powdery mildew and rust disease of vegetables, flowers and fruits.
Description
Technical field
The present invention relates to technical field of pesticide combination, particularly relate to a kind of bactericidal composition containing prothioconazoles and high-efficiency precision metalaxyl.
Background technology
Prothioconazoles is a kind of New-type wide-spectrum triazolinthione series bactericidal agent of Beyer Co., Ltd's development, and prothioconazoles toxicity is low, to human and environment safety.Prothioconazoles is mainly used in control cereal crop as numerous diseases such as wheat, barley, rape, peanut, paddy rice and legume crops.Almost there is good control efficiency, as the powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot, rust, stalk break, net blotch, moire disease etc. of Wheat and barley to all wheat class diseases.The soil-borne disease of oily Lay and peanut can also be prevented and treated, as stalk break, and main foliage disease, as gray mold, black spot, brown spot, balck shank, stalk break and rust etc.The chemistry of prothioconazoles (RS)-2-by name (its chemical structural formula is for 2-(1-chlorine cyclopropyl)-3-(2-chlorphenyl)-2-hydroxypropyl-1-2-dihydro-3-1,2,4-triazole-3-thioketones:
High-efficiency precision metalaxyl belongs to phenylamide; for efficient, low toxicity, low-residual, the lasting period is long, insecticide-applying way is diversified, the wide spectrum systemic fungicide of the equal excellence of protection and result for the treatment of; cauline leaf process, seed treatment and soil treatment can be made, have aobvious control efficiency of removing from office to the crop pest that downy mildew, phytophthora, pythium spp etc. cause.
In the real process of agricultural production, using chemical agent is the most effective means of control plant pest, but is the generation of disease drug resistance by the problem that chemical control disease the most easily produces.In the chemical control of bacteriosis, years of researches are carried out both at home and abroad, although some antibacterium medicaments have started to enter practical stage, but the medicament of chemosynthesis has cycle long, the shortcoming such as cost is high, toxicity is large, environmental pollution is serious, can not meet the requirement of agricultural sustainable development far away.And long-term use single pesticidal preparations continuously high dose, easily cause the problems such as the remaining of medicament, environmental pollution and resistance to pesticide resistance fungi development.And by contrast, exploitation is efficient with research, low toxicity, low-residual composite and mixture has small investment, the lead time is short and be subject to domestic and international attention, numerous and confused increasing develops dynamics.We are on the basis of lab screening and field trial, filter out prothioconazoles and high-efficiency precision metalaxyl carries out composite, have obvious synergistic effect.And about prothioconazoles and high-efficiency precision metalaxyl composite composition pesticide and apply and there is no people at present and reported.
Summary of the invention
Based on above situation, the object of the invention is to provide a kind of new and effective composition pesticide, effectively controls the diseases such as the gray mold on vegetables, flowers and fruits, powdery mildew, rust.
Technical scheme of the present invention is realized by following measures:
Contain a bactericidal composition for prothioconazoles and high-efficiency precision metalaxyl, active ingredient prothioconazoles and the high-efficiency precision metalaxyl two yuan of this composition pesticide are composite, and all the other are auxiliary element.In wherein said composition pesticide, the mass ratio of active ingredient prothioconazoles and high-efficiency precision metalaxyl is 1 ~ 50: 50 ~ 1, described composition pesticide of the present invention is through toxicity test experimental verification, when the mass ratio of prothioconazoles and high-efficiency precision metalaxyl is 1 ~ 10: 10 ~ 1, synergistic effect is optimum.
The formulations of pesticide that described composition pesticide of the present invention can be prepared are missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations, aqua.Wherein active ingredient prothioconazoles and high-efficiency precision metalaxyl gross mass in the formulation account for 1% ~ 80% of the whole quality of the pharmaceutical preparations, and when wherein accounting for 1% ~ 50%, toxicity reaches good balance with residual, and cost is also lower.
The specific embodiments of the formulations of pesticide that composition pesticide of the present invention is mixed with is as follows:
Described bactericidal composition is cream preparation, and the mass fraction of component is: prothioconazoles 1 ~ 50 part; High-efficiency precision metalaxyl 1 ~ 50 part; Conventional emulsifier 10 ~ 30 parts; Conventional solvents 20 ~ 50 parts; Conventional synergist 1 ~ 5 part.The concrete production stage of this cream preparation be first active ingredient prothioconazoles and high-efficiency precision metalaxyl are added dissolve completely in solvent after add emulsifier again, synergist becomes transparent and homogeneous oily liquids after stirring, filling, namely can be made into the cream preparation of the present composition.
Described bactericidal composition is suspending agent, and the mass fraction of component is: prothioconazoles 1 ~ 50 part; High-efficiency precision metalaxyl 1 ~ 50 part; Dispersant 5 ~ 20 parts; Antifreezing agent 1 ~ 5 part; Thickener 0.1 ~ 2 part; Defoamer 0.1 ~ 0.8 part; Penetrating agent 0 ~ 10 part; PH value regulator 0.1 ~ 5 part; Water, surplus.The concrete production stage of this suspending agent is for first to mix other auxiliary agents, mix through high speed shear, add active ingredient prothioconazoles and high-efficiency precision metalaxyl, abrading-ball 2 ~ 3 hours in ball crusher, make a diameter all at below 5mm, namely can be made into the aqueous suspension formulations of the present composition.
Described bactericidal composition is wetting powder, and the mass fraction of component is: prothioconazoles 1 ~ 50 part; High-efficiency precision metalaxyl 1 ~ 50 part; Dispersant 3 ~ 10 parts; Wetting agent 1 ~ 5 part; Filler, surplus.The concrete production stage of this wetting powder is: mixed with high-efficiency precision metalaxyl and dispersant, wetting agent and filler by active ingredient prothioconazoles by above-mentioned formula, uniform stirring in stirred tank, mixing after airslide disintegrating mill, namely can be made into the wetting powder of the present composition.
Described bactericidal composition is water dispersible granules, and the mass fraction of component is: prothioconazoles 1 ~ 50 part; High-efficiency precision metalaxyl 1 ~ 50 part; Dispersant 3 ~ 10 parts; Wetting agent 1 ~ 10 part; Disintegrant 1 ~ 5 part; Filler, surplus.The concrete production stage of this water dispersible granules is: mixed with high-efficiency precision metalaxyl and dispersant, wetting agent, disintegrant and filler by active ingredient prothioconazoles by above-mentioned formula, pulverize with micro jet, through mediating, then add in fluidized-bed granulation dryer and to carry out after granulation, drying, screening, through sample analysis, namely can be made into the water dispersible granules of the present composition.
Described bactericidal composition is aqueous emulsion, and the mass fraction of component is: prothioconazoles 1 ~ 50 part; High-efficiency precision metalaxyl 1 ~ 50 part; Emulsifier 3 ~ 30 parts; Solvent 5 ~ 15 parts; Stabilizing agent 2 ~ 15 parts; Antifreezing agent 1 ~ 5 part; Defoamer 0.1 ~ 8 part; Thickener 0.2 ~ 2 part; Water, surplus.The concrete production stage of this aqueous emulsion is: first prothioconazoles and high-efficiency precision metalaxyl, solvent and emulsifier, cosolvent are added together, and makes to be dissolved into uniform oil phase; By part water, antifreeze, other the insecticides adjuvant such as antimicrobial mixes uniformly aqueous phase; While high-speed stirred, oil phase is added aqueous phase in a kettle., slowly add water until reach phase inversion point, open clipper and carry out high speed shear, and add remaining water, shear about half an hour, form the aqueous emulsion of oil-in-water type, namely can be made into the aqueous emulsion of the present composition.
Described bactericidal composition is microemulsion, and the mass fraction of component is: prothioconazoles 1 ~ 50 part, high-efficiency precision metalaxyl 1 ~ 50 part, emulsifier 10 ~ 30 parts, antifreezing agent 1 ~ 8 part, stabilizing agent 0.5 ~ 10 part, Conventional solvents cosolvent 20 ~ 50 parts.Prothioconazoles and high-efficiency precision metalaxyl cosolvent are dissolved completely, then add other compositions such as emulsifier, antifreezing agent stabilizing agent, Homogeneous phase mixing, finally adds water, can be made into microemulsion after fully stirring.
Described bactericidal composition is granule, and the mass fraction of component is: prothioconazoles 1 ~ 50 part, high-efficiency precision metalaxyl 1 ~ 50 part, wetting dispersing agent 1 ~ 10 part; Thickener 0.1 ~ 5 part; Defoamer 0.1 ~ 5 part; Castor oil, surplus is supplied.Each components such as active ingredient prothioconazoles and high-efficiency precision metalaxyl, dispersant, stabilizing agent, defoamer and solvent are mixed in the ratio of filling a prescription, after putting into the grinding of sand milling still, sends into mixing in mixer for well-distribution and get product.
Described bactericidal composition is microcapsule formulations, and the mass fraction of component is: prothioconazoles 1 ~ 50 part, high-efficiency precision metalaxyl 1 ~ 50 part, 5 ~ 20 parts, urea; 5 ~ 20 parts, formaldehyde; Emulsifying dispersant 5 ~ 20 parts; Antifreezing agent 1 ~ 5 part; Thickener 0.1 ~ 2 part; Defoamer 0.1 ~ 0.8 part; Water, surplus.Urea and formaldehyde (amount of substance ratio is about l:1.5 ~ 2.0) is added in the there-necked flask that agitating device is housed, regulate the pH value of solution to about 8 ~ 9 with sodium hydroxide solution, then be warming up to 70 ~ 80 DEG C, be obtained by reacting stable urea resin prepolymer.Get a certain amount of prothioconazoles and high-efficiency precision metalaxyl is dissolved in cyclohexane, and add emulsifying dispersant in the solution, with vigorous stirring, the O/W type stable emulsion that to be made into the aqueous solution containing emulsifying dispersant be aqueous phase.Above-mentioned urea resin prepolymer is added in emulsion, adjust ph, polymerization reaction take place under acid catalysed conditions, oil phase substance is wrapped, form microcapsule granule.Slow intensification, solidification, temperature controls at 40 ~ 50 DEG C, hardening time 1h.Select to add appropriate auxiliary agent, stable microcapsules.
Described sterilization worm composition is aqua, and the mass fraction of component is: prothioconazoles 1 ~ 50 part, high-efficiency precision metalaxyl 1 ~ 50 part, wetting dispersing agent 0.1 ~ 30 part; Antifreezing agent 2 ~ 8 parts; Defoamer 0.1 ~ 1 part; Thickener 0.1 ~ 3 part; Spreader-sticker 5 ~ 15 parts; Water, surplus is supplied.By active ingredient prothioconazoles and high-efficiency precision metalaxyl, dissolve completely with cosolvent, then add other compositions such as dispersant, antifreezing agent, defoamer, Homogeneous phase mixing, finally adds water, after fully stirring, finished product.
Wherein above-described emulsifier is selected from calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, alkylphenol polyoxyethylene sulfosuccinate, styrylphenol polyoxyethylene ether, polyoxyethylene nonylphenol ether, castor oil polyoxyethylene ether, aliphatic acid polyethenoxy base ester, any one in polyoxyethylene aliphatic alcohol ether or more than one any mixtures than composition.
Described solvent is dimethylbenzene or biodiesel, toluene, diesel oil, methyl alcohol, ethanol, n-butanol, isopropyl alcohol, turpentine-based vegetable oil code name is ND-45, solvent naphtha, dimethyl formamide, dimethyl sulfoxide (DMSO), one or more in water equal solvent are arbitrarily than the mixture of composition.
It is LG-3, GY-D1252, GY-D1256, SNWGF-01 that described dispersant is selected from polycarboxylate code name, lignosulfonates code name is 201107,201108, alkylphenol polyoxyethylene methyl ether condensate sulfate, alkylsulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, polyoxyethylene carboxylate, aliphatic amine polyoxyethylene ether, one or more in fatty acid glyceride APEO.
Described wetting agent is selected from lauryl sodium sulfate, calcium dodecyl benzene sulfonate, Nekal BX, moistening bleeding agent F, alkylbenzenesulfonate polyoxyethylene triphen phosphenylic acid salt dimly, spaonin powder, silkworm excrement, one or more in soapberry powder.
Described disintegrant is selected from bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, one or more in sodium bicarbonate.
Described thickener is selected from xanthans, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, Magnesiumaluminumsilicate, in polyvinyl alcohol one or more.
Described stabilizing agent is selected from sodium citrate, the one in resorcinol.
Described antifreezing agent is selected from ethylene glycol, propane diols, one or more in glycerine.
Described defoamer is selected from silicone oil, silicone compound, C
10-20saturated fat acid compounds, C
8-10one or more of fatty alcohol.
Described filler is selected from kaolin, diatomite, bentonite, attapulgite, white carbon, starch, one or more in precipitated calcium carbonate.
The composite bactericide that the present invention is active ingredient with prothioconazoles and high-efficiency precision metalaxyl has obvious synergistic effect, delay the drug-fast generation in key, and reduce into product cost and use cost, effectively control the diseases such as the gray mold on vegetables, flowers and fruits, powdery mildew, rust.
Embodiment
For making technical scheme of the present invention, object and advantage are clearly understood, the following specific embodiment of the present invention is described, but the present invention is not limited to these examples.The mode that effect experimental of the present invention adopts indoor biometrics and field trial to combine, if no special instructions, the ratio below mentioned is all ratio of quality and the number of copies.
Embodiment: prothioconazoles and high-efficiency precision metalaxyl different ratio co-toxicity are tested.
1.1 reagent agent
The former medicine of 95% prothioconazoles, the former medicine of 95% high-efficiency precision metalaxyl, above-mentioned former medicine provides by research and development department of extra large rel medicine company limited company.
1.2 test targets
Never executed prothioconazoles and high-efficiency precision metalaxyl and cucumber of the same type to gather potted plantly be separated, for examination cucumber variety: Chang Chun Mi Ci from Shouguang, Shandong.
1.3 test method
1.3.1 medicament preparation
First use the former medicine of acetone solution, appropriate two former medicines are made into several different ratio by the result according to preliminary experiment, then it is stand-by with acetone, each process to be diluted to several concentration gradients respectively.
By susceptible cucumber variety Chang Chun Mi Ci cultivation in pot for growing seedlings, be placed in greenhouse and cultivate, plant grows to three to four leaf after dates, gathers the blade of identical leaf age, for cultivation and the mensuration of gray mold of cucumber germ.
1.3.2 the cultivation of gray mold of cucumber germ and the preparation of spore suspension
Gray mold of cucumber germ adopt plants method 20 DEG C, cultivate under the condition of 12h alternation of light and darkness, every 30d turns culture 1 time.With the conidium on sterile water wash-out incidence of leaf during inoculation, being mixed with spore concentration is l × 10
6the suspension of individual/mL.
1.3.3 strains tested sensitivity testing
Leaf dish moisturizing method is adopted to carry out toxicity test.First the blade of collection is prepared into the leaf dish that diameter is 1.5cm, random mixing, be placed in the series concentration liquid configured respectively and soak lh, each concentration 50 leaf dishes, test with the process of not adding medicine as blank, after immersion terminates, leaf faces up and puts on the blotting paper that identical liquor strength is wetting, liquid on leaf dish is blotted, the spore suspension l0L prepared is inoculated in leaf dish central authorities, room temperature is placed after 5min, is placed in 20 DEG C, cultivates under the condition of 12h alternation of light and darkness, measure the onset area on leaf dish after 10d, calculate EC
50.
The percentage accounting for leaf disc area according to lesion area divides disease level
0 grade: anosis;
1 grade: sorus area accounts for less than 5% of whole leaf area;
3 grades: sorus area accounts for below the 6%-10% of whole leaf area;
5 grades: sorus area accounts for below the 11%-20% of whole leaf area;
7 grades: sorus area accounts for below the 21%-50% of whole leaf area;
9 grades: sorus area accounts for more than 50% of whole leaf area;
1.3.4 mixture toxicity test and interpretation of result
Carry out the toxicity test of mixture according to mixed ratio by single dose toxicity test method.
If contrast lethality <5%, does not correct, contrast lethality, between 5%-20%, corrects by formula 2, and contrast lethality >20%, test need be reformed.
Be independent variable x with the logarithm value of drug concentration (mg/L), with the probability value of corrected mortality for dependent variable y, set up virulence regression equation formula respectively, adopt DPS software to calculate the EC of single dose and each proportioning mixture
50co-toxicity coefficient (CTC) is calculated according to the abundant method of Sun Yun.Co-toxicity coefficient CTC, computing formula is as follows: (take prothioconazoles as standard agent, its toxicity index is 100):
The EC of toxicity index (the TI)=prothioconazoles of high-efficiency precision metalaxyl
50the EC of/high-efficiency precision metalaxyl
50× 100
The EC of true toxicity index (the ATI)=prothioconazoles of M
50the EC of/M
50× 100
TI × P high-efficiency precision metalaxyl of the TI × P prothioconazoles+high-efficiency precision metalaxyl of theoretical toxicity index (the TTI)=prothioconazoles of M
TTI × 100 of the ATI/M of co-toxicity coefficient (the CTC)=M of M
In formula:
M is the mixture of prothioconazoles and high-efficiency precision metalaxyl different ratio
P prothioconazoles is the ratio of prothioconazoles shared by mixture
P high-efficiency precision metalaxyl is the ratio of high-efficiency precision metalaxyl shared by mixture.
2.1 toxicity test results
Table 1 prothioconazoles and high-efficiency precision metalaxyl are to the toxicity test of gray mold of cucumber
As can be seen from the table, the result of the test of different proportion proportioning shows, dilute respectively in active ingredient ratio and all show stronger synergistic effect, wherein with prothioconazoles: time high-efficiency precision metalaxyl is 1:10 ~ 10:1, synergistic effect is best, suggestion carries out further field control effectiveness test to suitable proportion about 1:10 ~ 10:1 mixture preparation, to evaluate its field practical application effect.
3, the experimental result of field trial control wheat powdery mildew, gray mold of cucumber
3.1 field trial control wheat powdery mildews
3.1.1 test method
Test site is in great Tong Qiao village, capital town, Fengyang County, and be wheat for studying thing, kind is short morning 781, broadcasts sowing, and growing way is better, and test establishes every mu to establish contrast totally 10 process.Often process repetition 4 times, random district group arranges, plot area 30 square metres.
3.1.2 control time and number of times
Before dispenser, after the 1st medicine after 7 days and the 2nd dispenser 7 days, 14 days, every community adopted diagonal 5 sampling, investigates 20 strains at often, before blooming, 2 leaves are got in every strain from upper end, sword-like leave 2 leaf is got in the every strain of Post flowering, by leaf classification investigation occurring degree, calculates disease and refers to and control efficiency.
Grade scale is as follows:
0 grade: anosis;
1 grade: lesion area accounts for less than 5% of one-piece blade area;
3 grades: lesion area accounts for the 6%-15% of one-piece blade area;
5 grades: lesion area accounts for the 16%-25% of one-piece blade area;
7 grades: lesion area accounts for the 26%-50% of one-piece blade area;
9 grades: lesion area accounts for more than 50% of one-piece blade area.
3.1.3 drug effect computational methods
Sick leaf rate (%)=sick number of sheets/investigate the total number of sheets × 100
Disease index=∑ (the sick number of sheets × relative level numerical value at different levels)/(investigating the total number of sheets × 9) × 100
Control efficiency (%)=(1-(before blank district medicine after disease index × treatment region medicine disease index)/(after blank district medicine before disease index × treatment region medicine disease index)) × 100.
3.1.4 poisoning investigation method
Whether after dispenser, continuous 14d estimates medicament has poisoning to crop.
3.1.5 result of the test and analysis
The effect of wheat powdery mildew prevented and treated by table 2 respectively process
Prothioconazoles and high-efficiency precision metalaxyl composite bactericide control successful higher than prothioconazoles and high-efficiency precision metalaxyl single dose for wheat powdery mildew as shown in Table 2, and bactericidal effect increases progressively with the increase of dosage.According to field range estimation, within the scope of test dose, plant growth is normal, and the poisoning phenomenon to wheat does not all appear in each treatment agent, illustrates that it is safe to wheat.Advise that the bactericide different from the mechanism of action is used in combination to delay the drug-fast generation of germ.
3.2 field trial control gray molds of cucumber
3.2.1 test method
Test on Shandong Pingdu City cucumber ground, test kind is middle peasant No. 8, and often process 4 times and repeat, every community double diagonal line investigates 5 points, often some investigation 3 strain cucumber, and record occurring degree by staging, grade scale is as follows:
0 grade: anosis;
1 grade: scab heap area accounts for less than 5% of whole leaf area;
3 grades: scab heap area accounts for below the 6%-10% of whole leaf area;
5 grades: scab heap area accounts for below the 11%-20% of whole leaf area;
7 grades: scab heap area accounts for below the 21%-50% of whole leaf area;
9 grades: scab heap area accounts for more than 50% of whole leaf area.
3.2.2 control time and number of times
Test altogether investigate 4 times, before medicine radix investigation, first time medicine after 7 days, second time 7 days and medicine after within 15 days, investigate.
3.2.3 drug effect computational methods
Sick leaf rate (%)=sick number of sheets/investigate the total number of sheets × 100
Disease index=∑ (the sick number of sheets × relative level numerical value at different levels)/(investigating the total number of sheets × 9) × 100
Control efficiency (%)=(1-(before blank district medicine after disease index × treatment region medicine disease index)/(after blank district medicine before disease index × treatment region medicine disease index)) × 100.
3.2.4 poisoning investigation method
Whether after dispenser, continuous 15d estimates medicament has poisoning to crop.
3.2.5 result of the test and analysis
Table 3 different disposal prevents and treats measurement result to gray mold of cucumber
Shown by above field experiment, prothioconazoles and high-efficiency precision metalaxyl complex preparation are obviously better than single dose for the preventive effect of gray mold of cucumber, and bactericidal effect increases progressively with the increase of dosage.According to field range estimation, within the scope of test dose, plant growth is normal, occurs without poisoning situation, significant for agricultural produce, is worthy to be popularized.
In sum, the present invention contains the bactericidal composition of prothioconazoles and high-efficiency precision metalaxyl, have good control efficiency, and it is to Target crops safety to wheat powdery mildew, gray mold.Complex preparation not only increases preventive effect, and expands the control to bacterium, so this compounded combination tool in production practices is of great significance.
Claims (4)
1. one kind contains the bactericidal composition of prothioconazoles and high-efficiency precision metalaxyl, it is characterized in that: the active ingredient of this composition pesticide is prothioconazoles and high-efficiency precision metalaxyl binary built, all the other are auxiliary element, and wherein the mass ratio of active ingredient prothioconazoles and high-efficiency precision metalaxyl is 1 ~ 50: 50 ~ 1.
2. composition pesticide according to claim 1, is characterized in that: prothioconazoles and high-efficiency precision metalaxyl gross weight in the formulation account for 1% ~ 80% of the whole quality of the pharmaceutical preparations.
3. composition pesticide according to claim 2, is characterized in that: prothioconazoles and high-efficiency precision metalaxyl gross weight in the formulation account for 1% ~ 50% of the whole quality of the pharmaceutical preparations.
4. the composition pesticide according to claim 1 or 2 or 3, is characterized in that: the formulation of this composition pesticide is missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule formulations, granule, aqua.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113142232A (en) * | 2021-04-22 | 2021-07-23 | 安徽辉隆集团银山药业有限责任公司 | Seed treatment agent containing prothioconazole, metalaxyl-M and clothianidin and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103783046A (en) * | 2013-12-09 | 2014-05-14 | 海利尔药业集团股份有限公司 | Fungicidal composition containing prothioconazole and pyrimethanil |
| CN104621129A (en) * | 2013-11-15 | 2015-05-20 | 南京华洲药业有限公司 | Sterilization composition containing prothioconazole and metalaxyl-M and application thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104621129A (en) * | 2013-11-15 | 2015-05-20 | 南京华洲药业有限公司 | Sterilization composition containing prothioconazole and metalaxyl-M and application thereof |
| CN103783046A (en) * | 2013-12-09 | 2014-05-14 | 海利尔药业集团股份有限公司 | Fungicidal composition containing prothioconazole and pyrimethanil |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113142232A (en) * | 2021-04-22 | 2021-07-23 | 安徽辉隆集团银山药业有限责任公司 | Seed treatment agent containing prothioconazole, metalaxyl-M and clothianidin and application thereof |
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