CN109374353B - Automatic sampling device for automatic analyzer - Google Patents
Automatic sampling device for automatic analyzer Download PDFInfo
- Publication number
- CN109374353B CN109374353B CN201811615024.2A CN201811615024A CN109374353B CN 109374353 B CN109374353 B CN 109374353B CN 201811615024 A CN201811615024 A CN 201811615024A CN 109374353 B CN109374353 B CN 109374353B
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- CN
- China
- Prior art keywords
- automatic
- motor
- connecting column
- vertical connecting
- plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000005070 sampling Methods 0.000 title claims abstract description 17
- 238000005520 cutting process Methods 0.000 claims abstract description 29
- 230000004927 fusion Effects 0.000 claims abstract description 12
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229910052742 iron Inorganic materials 0.000 claims abstract description 5
- 238000005476 soldering Methods 0.000 claims abstract description 5
- 239000007788 liquid Substances 0.000 claims description 12
- 230000001360 synchronised effect Effects 0.000 claims description 3
- 239000004020 conductor Substances 0.000 claims description 2
- 239000000155 melt Substances 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 4
- 210000000078 claw Anatomy 0.000 description 4
- 239000011111 cardboard Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 206010011409 Cross infection Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
- G01N2001/1418—Depression, aspiration
- G01N2001/1427—Positive displacement, piston, peristaltic
Abstract
The invention discloses an automatic sampling device for an automatic analyzer, which comprises a multidimensional movement mechanism, wherein a vertical connecting column driven by a translation motor, a lifting motor and a rotating motor is arranged on the multidimensional movement mechanism, and a fusion cutter and a pipetting gun are arranged on the vertical connecting column; the fusion cutter is an electric soldering iron with a cylindrical cutting head at the tail end, and the bottom surface of the cylindrical cutting head is obliquely arranged; the pipette comprises a suction cylinder connected with a vertical connecting column, a piston rod driven by a pushing motor is sleeved in the suction cylinder, a rubber clamping block is sleeved at the tail end of a suction head communicated with the suction cylinder, and the rubber clamping block is of an inverted cone structure with a limiting baffle at the top. The invention has simple structure, convenient use, safety and no pollution, and meets the requirement of batch detection of an automatic analyzer and the working beat of automatic analysis.
Description
Technical Field
The invention relates to the technical field of automatic sampling of a pipette, in particular to an automatic sampling device for an automatic analyzer.
Background
At present, manual suction samples are matched with an analyzer to analyze samples. When the existing sample bottle with the plastic screwing cover is used for sampling, the bottle cover is manually unscrewed, and liquid is taken through the liquid-transferring gun. When the sample bottle is matched with the automatic analyzer, if the sampling method is still adopted, the bottle caps are required to be completely taken down and put into the analyzer, and the risk of toppling of the bottle bodies exists in the moving process or the sampling process of the sample bottle; another concept is to integrate a melt-cutting device in an automatic analyzer, i.e. to melt-cut an opening in the cap and then sample the sample, so that liquid pouring can be avoided. However, when the conventional fusion cutter is adopted, the cut part of the bottle cap naturally falls into the bottle body, so that sample pollution is caused. Secondly, in order to prevent cross infection, each detection sample needs to be matched with a pipette tip, namely, the pipette tip needs to be replaced before the pipette is used for taking out liquid. The existing pipetting gun mostly adopts manual installation gun heads, liquid sucking and discharging and unloading gun heads, and when the number of samples is large, more time and energy are required to be consumed; secondly, when the operation is not standard, the sample is easy to pollute, and the accuracy of the detection result is affected; again, it is clearly impractical to use a manually operated pipette in conjunction with an automatic analyzer.
Disclosure of Invention
In order to solve the above problems, the present invention provides an automatic sampling device for an automatic analyzer, which has the following specific technical scheme:
the automatic sampling device for the automatic analyzer comprises a multidimensional movement mechanism, wherein a vertical connecting column driven by a translation motor, a lifting motor and a rotating motor is arranged on the multidimensional movement mechanism, and a fusion cutter and a pipetting gun are arranged on the vertical connecting column; the fusion cutter is an electric soldering iron with a cylindrical cutting head at the tail end, and the bottom surface of the cylindrical cutting head is obliquely arranged; the pipette comprises a suction cylinder connected with a vertical connecting column, a piston rod driven by a pushing motor is sleeved in the suction cylinder, a rubber clamping block is sleeved at the tail end of a suction head communicated with the suction cylinder, and the rubber clamping block is of an inverted cone structure with a limiting baffle at the top.
The multidimensional movement mechanism comprises a vertical plate, a moving frame is arranged on the vertical plate in a sliding manner along the horizontal direction, the moving frame is connected with a ball screw driven by a translation motor, a lifting motor is arranged on a top plate of the moving frame, a lifting plate is arranged in the moving frame in a sliding manner, the lifting plate is connected with the ball screw driven by the lifting motor, a rotating motor is arranged on the lifting plate, the rotating motor is connected with a vertical connecting column through a synchronous belt mechanism, and the vertical connecting column penetrates through a bottom plate of the moving frame and extends downwards.
The included angle between the inclined surface of the cylindrical cutting head and the horizontal plane is 30-60 degrees.
The cylindrical cutting head is internally provided with a pushing column, and the pushing column and the bottom of the cylindrical cutting head are arranged in a coplanar manner.
Be provided with the guide sleeve between suction tube and the vertical spliced pole, be provided with in the guide sleeve bulldoze motor driven ball, ball's screw nut links to each other with bulldozing the pole, and the guide sleeve is provided with from the top down outward and is used for the card to solid the card board of suction tube, goes up clamping and lower clamping, the piston rod pass through the bulldozing the board with bulldoze the pole and link to each other.
The upper clamping clamp and the lower clamping clamp are identical in structure and comprise a left clamping jaw and a right clamping jaw which are hinged with the guide sleeve, and the left clamping jaw and the right clamping jaw are connected through a return spring.
The automatic analyzer is simple in structure, convenient to use, safe and pollution-free, under the action of the multidimensional movement mechanism, the fusion cutting device and the liquid transferring gun can alternately work, fusion cutting is firstly carried out on the bottle cap of the sample bottle, then liquid suction is carried out on the sample bottle, meanwhile, the liquid transferring gun can realize automatic replacement of the gun head under the matching action of the gun head installer and the gun head unloader, and the requirements of batch detection of the automatic analyzer and the working beat of automatic analysis are met.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Fig. 2 is a schematic view of the structure of the melter of fig. 1.
Detailed Description
As shown in fig. 1, the automatic sampling device for an automatic analyzer according to the present invention includes a multi-dimensional movement mechanism having translation, elevation and rotation functions, and a melt cutter and a pipette connected thereto.
Specifically, the multidimensional movement mechanism comprises a vertical plate 1.1, a moving frame 1.2 is slidably arranged on the vertical plate 1.1 along the horizontal direction, the moving frame 1.2 is connected with a ball screw driven by a translation motor 1.3, a lifting motor 1.4 is arranged on a top plate of the moving frame 1.2, a lifting plate 1.5 is slidably arranged in the moving frame 1.2, the lifting plate 1.5 is connected with the ball screw driven by the lifting motor 1.4, a rotating motor 1.6 is arranged on the lifting plate 1.5, the rotating motor 1.6 is connected with a vertical connecting column 1.7 through a synchronous belt mechanism, and the vertical connecting column 1.7 penetrates through a bottom plate of the moving frame 1.2 and extends downwards. Thus, the vertical connection column 1.7 can perform translational, lifting and rotational functions.
One side of the vertical connecting column 1.7 is connected with a fusion cutter, the fusion cutter is an electric soldering iron with a cylindrical cutting head 2.1 at the tail end, and the bottom surface of the cylindrical cutting head 2.1 is obliquely arranged to form an inclined plane with an included angle of 30-60 degrees with the horizontal plane. Further, a pushing post 2.2 made of a non-heat conducting material is installed in the cylindrical cutting head 1, and the pushing post 2.2 is arranged coplanar with the bottom of the cylindrical cutting head 2.1, that is, the bottom surface of the pushing post 2.2 has the same inclination with the bottom surface of the cylindrical cutting head 2.1.
The other side of the vertical connecting column 1.7 is connected with a pipette gun consisting of a suction cylinder 3.1, a piston rod 3.2 and a suction head 3.3. Specifically, install guide sleeve 3.4 on the vertical spliced pole 1.7, install the ball that bulldozes motor 3.5 drive in the guide sleeve 3.4, ball's screw nut links to each other with bulldozing pole 3.6, and the guide sleeve 3.4 installs outward from the top down and inserts cardboard 3.7, goes up clamping 3.8 and lower clamping 3.9, it links to each other with suction cylinder 3.1 to insert cardboard 3.7, last clamping 3.8 and lower clamping 3.9, and piston rod 3.2 links to each other with bulldozing pole 3.6 through bulldozing board 3.10. The tail end of the suction head 3.3 is sleeved with a rubber clamping block 3.11 for connecting the gun head of the liquid-transfering gun, and the rubber clamping block 3.11 is of an inverted cone structure with a limiting baffle at the top. The upper clamping clamp 3.8 and the lower clamping clamp 3.9 have the same structure and comprise a left claw and a right claw which are hinged with the guide sleeve 3.4, and the left claw and the right claw are connected through a return spring, so that the pipette gun with different models (different outer diameters of the finger suction barrels) can be clamped.
In general, the present invention is used in conjunction with a gun head installer and a gun head unloader. The gun head installer adopts a common commercial gun head box or other structures, and the gun head unloader comprises a collecting box and a gun head clamping plate arranged on the collecting box. Under the action of the multidimensional movement mechanism, the pipetting gun moves to the position above the gun head installer, and the suction head 3.3 moves downwards after aligning with the disposable gun head opening, so that the gun head is sleeved on the rubber clamping block 3.11 of the suction head 3.3; then, alternately moving the fusion cutter and the liquid transferring gun to the upper part of the sample bottle, fusing and cutting the bottle cap, sucking the sample, and then injecting the sample in the liquid transferring gun into a liquid storage container matched with the analyzer, such as a sample cup; and finally, moving the liquid-transferring gun to a gun head clamping plate of a gun head unloader, enabling the upper surface of the gun head to be in contact with the lower surface of the gun head clamping plate, and then lifting the suction head 3.3 to separate the gun head from the rubber clamping block 3.11. Thus, one automatic sampling operation is completed.
The bottle cap melt cutting process specifically comprises the following steps: firstly, electrifying to enable the electric soldering iron to reach the set temperature, and then enabling the cylindrical cutting head 2.1 to vertically downwards melt and cut the bottle cap of the sample bottle. Because the bottom of the cylindrical cutting head 2.1 is a bevel, one end of the lower end of the cylindrical cutting head is contacted with the bottle cap for fusion cutting, and the other end of the bottle cap is still connected with the bottle cap main body; along with the continuous downward pushing of the cylindrical cutting head 2.1, the cutting contour on the bottle cap is gradually prolonged, and the cut part moves downward to be separated from the bottle cap main body under the action of the pushing column 2.2, so as to form a suction hole for the pipette gun head to pass through. In order to avoid that the root of the cut-off part is thoroughly separated from the bottle cap main body, so that the cut-off part falls into the sample bottle, and at the end point of the cut-off, the highest point of the chamfer of the cylindrical cutting head 2.1 still needs to be above the bottle cap.
Claims (5)
1. An automatic sampling device for an automatic analyzer, characterized by:
the automatic liquid transferring device comprises a multidimensional movement mechanism, wherein a vertical connecting column driven by a translation motor, a lifting motor and a rotating motor is arranged on the multidimensional movement mechanism, and a melt cutter and a liquid transferring gun are arranged on the vertical connecting column;
the fusion cutter is an electric soldering iron with a cylindrical cutting head at the tail end, and the bottom surface of the cylindrical cutting head is obliquely arranged; a pushing column made of non-heat-conducting material is arranged in the cylindrical cutting head, and the pushing column and the bottom of the cylindrical cutting head are arranged in a coplanar manner;
the pipetting gun consists of a suction cylinder, a piston rod and a suction head; a guide sleeve is arranged on the vertical connecting column, a ball screw driven by a pushing motor is arranged in the guide sleeve, a screw nut of the ball screw is connected with a pushing rod, an inserting clamping plate, an upper clamping clip and a lower clamping clip are arranged outside the guide sleeve from top to bottom, and the inserting clamping plate, the upper clamping clip and the lower clamping clip are connected with a suction cylinder; a piston rod driven by a pushing motor is sleeved in the suction cylinder, and the piston rod is connected with the pushing rod through a pushing plate; the end of the suction head communicated with the suction cylinder is sleeved with a rubber clamping block, and the rubber clamping block is of an inverted cone structure with a limiting baffle at the top.
2. The automatic sampling device for an automatic analyzer of claim 1, wherein: the multidimensional movement mechanism comprises a vertical plate, a moving frame is arranged on the vertical plate in a sliding manner along the horizontal direction, the moving frame is connected with a ball screw driven by a translation motor, a lifting motor is arranged on a top plate of the moving frame, a lifting plate is arranged in the moving frame in a sliding manner, the lifting plate is connected with the ball screw driven by the lifting motor, a rotating motor is arranged on the lifting plate, the rotating motor is connected with a vertical connecting column through a synchronous belt mechanism, and the vertical connecting column penetrates through a bottom plate of the moving frame and extends downwards.
3. The automatic sampling device for an automatic analyzer of claim 1, wherein: the included angle between the inclined surface of the cylindrical cutting head and the horizontal plane is 30-60 degrees.
4. The automatic sampling device for an automatic analyzer of claim 1, wherein: a guide sleeve is arranged between the suction cylinder and the vertical connecting column.
5. The automatic sampling device for an automatic analyzer of claim 4, wherein: the upper clamping clamp and the lower clamping clamp are identical in structure and comprise a left clamping jaw and a right clamping jaw which are hinged with the guide sleeve, and the left clamping jaw and the right clamping jaw are connected through a return spring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811615024.2A CN109374353B (en) | 2018-12-27 | 2018-12-27 | Automatic sampling device for automatic analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811615024.2A CN109374353B (en) | 2018-12-27 | 2018-12-27 | Automatic sampling device for automatic analyzer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109374353A CN109374353A (en) | 2019-02-22 |
| CN109374353B true CN109374353B (en) | 2023-09-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811615024.2A Active CN109374353B (en) | 2018-12-27 | 2018-12-27 | Automatic sampling device for automatic analyzer |
Country Status (1)
| Country | Link |
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| CN (1) | CN109374353B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111235031B (en) * | 2020-03-11 | 2023-04-07 | 广州医科大学附属第三医院（广州重症孕产妇救治中心、广州柔济医院） | Intelligent semen optimization system |
| CN111346682B (en) * | 2020-03-11 | 2022-12-06 | 广州医科大学附属第三医院（广州重症孕产妇救治中心、广州柔济医院） | Liquid accurate suction proportioning system |
| CN111514952A (en) * | 2020-05-14 | 2020-08-11 | 广东体必康生物科技有限公司 | Pipetting device and method capable of self-checking air tightness and accurately extracting |
| CN115569680B (en) * | 2022-10-11 | 2023-08-29 | 成都迪安医学检验所有限公司 | Magnetic force controllable ceiling type pipettor |
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2018
- 2018-12-27 CN CN201811615024.2A patent/CN109374353B/en active Active
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| Publication number | Publication date |
|---|---|
| CN109374353A (en) | 2019-02-22 |
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Effective date of registration: 20240226 Address after: 323-K, 3rd Floor, Comprehensive Xinxing Phase I, No.1 Haihong Road, Fubao Community, Fubao Street, Futian District, Shenzhen City, Guangdong Province, 518000 Patentee after: Lepaien (Shenzhen) Biotechnology Co.,Ltd. Country or region after: China Address before: No. 3, Building 3, Yard 25, Jingwu Road, Jinshui District, Zhengzhou City, Henan Province, 450000 Patentee before: Yang Yongjun Country or region before: China |