CN218973943U - Automatic liquid-based cell pelleter - Google Patents

Abstract

The utility model relates to the technical field of cell detection, in particular to an automatic liquid-based cell pelleter which comprises a rack, wherein a workbench is arranged on the rack; the carrying assembly is arranged on the workbench and can move in a three-dimensional space; the electric claw assembly is arranged on the carrying assembly; the oscillator is arranged on the workbench and is used for oscillating the sample bottle; the clamping device is fixedly arranged on the workbench; the centrifugal machine is arranged on the workbench; the pipetting assembly is arranged on the carrying assembly; go film-making storehouse subassembly, go film-making storehouse subassembly setting to be in on the workstation. The utility model can realize automatic film-making work, ensure the accuracy of liquid transfer and ensure film-making effect.

Description

Automatic liquid-based cell pelleter

Technical Field

The utility model relates to the technical field of cell detection, in particular to an automatic liquid-based cell pelleter.

Background

In medical testing, it is often necessary to slide and stain a cell sample for better visualization. The traditional centrifugal film-making process adopts manual operation, and has the following problems due to complicated actions: 1. the manual flaking workload is large, and workers are easy to fatigue; 2. the film-making action is complicated, the time is difficult to control and is consistent, the film-making effect depends on the proficiency of manpower, and the film-making effect is uneven; 3. the manual liquid adding amount is difficult to accurately control.

Thus, there is a need for an automated liquid-based cell pelleter that addresses the above-described problems.

Disclosure of Invention

The utility model aims to provide an automatic liquid-based cell pelleter which can realize automatic pelleter work, ensure accurate liquid transfer amount and ensure pelleter effect.

To achieve the purpose, the utility model adopts the following technical scheme:

an automated liquid-based cell pelleter comprising:

the machine frame is provided with a workbench;

the carrying assembly is arranged on the workbench and can move in a three-dimensional space;

the electric claw assembly is arranged on the carrying assembly;

the oscillator is arranged on the workbench and is used for oscillating the sample bottle;

the clamping device is fixedly arranged on the workbench and can clamp the sample bottle, and the electric claw assembly can remove the bottle cap of the sample bottle;

the centrifugal machine is arranged on the workbench, and a flaking bin assembly is arranged on the centrifugal machine;

the pipetting assembly is arranged on the carrying assembly and can move the liquid in the sample bottle into the flaking bin assembly;

go the film-making storehouse subassembly, go the film-making storehouse subassembly setting to be in on the workstation, accomplish the centrifugation the film-making storehouse subassembly can be fixed go on the film-making storehouse subassembly, go the film-making storehouse subassembly can with liquid in the film-making storehouse subassembly is fallen, the electric claw subassembly can take out the slide in the film-making storehouse subassembly.

Further, the electric claw assembly comprises a first motor, a second motor and a first clamping jaw assembly, the first motor is arranged on the carrying assembly, the first motor is in transmission connection with the second motor, the second motor is in transmission connection with the first clamping jaw assembly, the first motor can drive the first clamping jaw assembly to rotate through the second motor, and the second motor can drive the first clamping jaw assembly to open or clamp.

Further, the clamping device comprises a first air cylinder and a clamping claw, the first air cylinder is fixedly arranged on the workbench, the clamping claw is connected with a piston rod of the first air cylinder, and the first air cylinder can drive the clamping claw to clamp or loosen.

Further, the pipetting component comprises a pump component and a liquid taking component, the pump component is arranged on the workbench, the pump component is communicated with the liquid taking component, the liquid taking component is arranged on the carrying component, the pump component can transfer samples in the sample bottles to the flaking bin component through the liquid taking component, and the flaking bin component is added with buffer liquid.

Further, the pump assembly comprises a liquid drawing pump and a liquid injection pump, the liquid taking assembly comprises a pipette, a first conduit and a second conduit, the pipette is arranged on the carrying assembly, the first conduit and the second conduit are arranged in the pipette, one end of the first conduit is communicated with the liquid drawing pump, and one end of the second conduit is communicated with the liquid injection pump.

Further, the carrying assembly is provided with a lifting assembly, the lifting assembly is in transmission connection with the pipette, and the lifting assembly can drive the pipette to lift in the vertical direction.

Further, still include the guide assembly, the guide assembly includes slide rail, slider and guide block, the slide rail is fixed to be set up on the transport subassembly, the slider slides and sets up on the slide rail, the pipette wears to establish in the guide block, just the pipette with the slider is connected.

Further, the pipette further comprises a support, a pipette tip is arranged on the support, and the pipette can be inserted into the pipette tip and drive the pipette tip to move.

Further, go film-making storehouse subassembly to include rotating electrical machines, driving motor and second clamping jaw subassembly, the rotating electrical machines sets up on the workstation, just the rotating electrical machines with the driving motor transmission is connected, driving motor with second clamping jaw subassembly transmission is connected, the rotating electrical machines can pass through driving motor drives second clamping jaw subassembly rotates, driving motor can drive second clamping jaw subassembly opens or presss from both sides tight action.

Further, a waste port is formed in the workbench, and a waste barrel communicated with the waste port is arranged on the rack.

The utility model has the beneficial effects that:

the utility model provides an automatic liquid-based cell pelleter, which is characterized in that a carrying assembly, an oscillator, a clamping device, a pelleter removing assembly and a centrifugal machine are arranged on a workbench, and an electric claw assembly is arranged on the carrying assembly. After the sample bottle oscillates on the oscillator, the carrying assembly clamps the sample bottle to the clamping device through the electric claw assembly, then the electric claw assembly removes the bottle cap, the liquid in the sample bottle is moved into the slide making bin assembly placed in the centrifugal machine through the liquid transferring assembly, the centrifugal machine starts to work for centrifugation, after the liquid centrifugation is completed, the electric claw assembly clamps the slide making bin assembly to move to the slide making bin assembly through the carrying assembly, the slide making bin assembly pours the liquid in the slide making bin assembly, and then the electric claw assembly takes the slide out and places the slide into the material box. At this in-process, realize automatic film-making work, adopt the pipetting module to carry out automatic pipetting moreover, can guarantee to move the liquid measure accurate, guarantee the film-making effect.

Drawings

FIG. 1 is a schematic diagram of an automated liquid-based cell pelleter of the present utility model;

FIG. 2 is a schematic view of a pipetting assembly and a lifting assembly in an automated liquid-based cell pelleter of the utility model;

FIG. 3 is a schematic illustration of an assembly of an automatic liquid-based cell pelleter to a pelleter warehouse according to the present utility model;

FIG. 4 is a schematic illustration of a fixture in an automated liquid-based cell pelleter according to the present utility model.

In the figure:

1. a frame; 11. a work table; 12. a waste bin; 2. a handling assembly; 21. a first motion module; 22. a second motion module; 23. a third motion module; 24. an electric claw assembly; 25. a first jaw assembly; 3. a pipetting assembly; 31. a liquid pump; 32. a liquid injection pump; 33. a pipette; 34. a belt wheel motor; 35. a belt; 36. a guide block; 4. an oscillator; 41. a sample bottle; 5. a bracket; 51. pipetting gun heads; 6. a centrifuge; 7. a clamping device; 71. a first cylinder; 72. clamping claws; 8. removing a flaking bin assembly; 81. a rotating electric machine; 82. a driving motor; 9. a tabletting bin assembly; 91. a rubber cylinder; 92. and a supporting plate.

Detailed Description

The technical scheme of the utility model is further described below with reference to the attached drawings and the embodiments. It is to be understood that the specific embodiments described herein are merely illustrative of the utility model and are not limiting thereof. It should be further noted that, for convenience of description, only some, but not all of the drawings related to the present utility model are shown.

In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixed or removable, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

In the present utility model, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.

In medical testing, it is often necessary to slide and stain a cell sample for better visualization. In order to realize the automatic operation of cell pelleting, and ensure the accurate liquid transfer amount and the pelleting effect, the utility model provides an automatic liquid-based cell pelleter as shown in figures 1-4. The automatic liquid-based cell pelleter comprises a frame 1, a carrying assembly 2, an electric claw assembly 24, an oscillator 4, a clamping device 7, a centrifugal machine 6, a pipetting assembly 3 and a pelleter removing bin assembly 8.

Wherein, the frame 1 is provided with a workbench 11; the carrying assembly 2 is arranged on the workbench 11 and can move in a three-dimensional space; the electric claw assembly 24 is arranged on the carrying assembly 2; the oscillator 4 is provided on the table 11 for oscillating the sample bottle 41; the clamping device 7 is fixedly arranged on the workbench 11, can clamp the sample bottle 41, and the electric claw assembly 24 can remove the bottle cap of the sample bottle 41; the centrifugal machine 6 is arranged on the workbench 11, and the tablet making bin assembly 9 is arranged on the centrifugal machine 6; the pipetting assembly 3 is arranged on the carrying assembly 2, and the pipetting assembly 3 can move the liquid in the sample bottle 41 into the pelleter assembly 9; go film-making storehouse subassembly 8 setting on workstation 11, accomplish centrifugal film-making storehouse subassembly 9 can fix on going film-making storehouse subassembly 8, go film-making storehouse subassembly 8 and can pour the liquid in the film-making storehouse subassembly 9, electric claw subassembly 24 can take out the slide in the film-making storehouse subassembly 9.

After the sample bottle 41 oscillates on the oscillator 4, the carrying assembly 2 transfers the sample bottle 41 to the clamping device 7 to clamp through the electric claw assembly 24, then the electric claw assembly 24 removes the bottle cap, the liquid in the sample bottle 41 is moved into the flaking bin assembly 9 placed in the centrifugal machine 6 by the liquid transferring assembly 3, the centrifugal machine 6 starts to work for centrifugation, after the liquid centrifugation is completed, the electric claw assembly 24 clamps the flaking bin assembly 9 to move to the flaking bin assembly 8 through the carrying assembly 2, the liquid in the flaking bin assembly 9 is poured out by the flaking bin assembly 8, and then the glass slide is taken out by the electric claw assembly 24 and placed into a material box. At this in-process, realize automatic film-making work, adopt pipetting module 3 to carry out automatic pipetting moreover, can guarantee to move the liquid measure accurate, guarantee the film-making effect.

Further, the carrying assembly 2 is of a triaxial movement structure and comprises a first movement module 21, a second movement module 22 and a third movement module 23, the first movement module 21 is arranged on the workbench 11, the second movement module 22 is arranged on the first movement module 21, the second movement module 22 is in transmission connection with the first movement module 21, and the first movement module 21 can drive the second movement module 22 to move along the X-axis direction; the third movement module 23 is arranged on the second movement module 22, the third movement module 23 is in transmission connection with the second movement module 22, and the second movement module 22 can drive the third movement module 23 to move along the Y-axis direction; the electric claw assembly 24 is arranged on the third movement module 23, the electric claw assembly 24 is in transmission connection with the third movement module 23, and the third movement module 23 can drive the electric claw assembly 24 to move up and down along the Z-axis direction. Through the arrangement, the carrying assembly 2 can drive the electric claw assembly 24 to realize three-dimensional space movement.

Further, the electric claw assembly 24 includes a first motor, a second motor and a first clamping jaw assembly 25, the first motor is disposed on the third moving module 23 of the carrying assembly 2, the first motor is in transmission connection with the second motor, the second motor is in transmission connection with the first clamping jaw assembly 25, the first motor can drive the first clamping jaw assembly 25 to rotate through the second motor, and the second motor can drive the first clamping jaw assembly 25 to open or clamp. Specifically, the first jaw assembly 25 includes a first clamping member, a second clamping member, a first gear, a first rack and a second rack, the first rack is connected with the first clamping member, the second rack is connected with the second clamping member, the first gear is meshed with the first rack and the second rack, and the first gear is connected with an output shaft of the second motor. The first gear can be driven to rotate through the second motor, so that the first clamping piece and the second clamping piece are close to each other or far away from each other. The first motor can drive the first clamping jaw assembly 25 to rotate through the second motor, so that screwing action is realized. By adopting motor transmission, the transmission precision can be ensured. In other embodiments, a lead screw and nut structure may be used instead of the rack and pinion structure, without limitation.

Further, the clamping device 7 comprises a first air cylinder 71 and a clamping claw 72, the first air cylinder 71 is fixedly arranged on the workbench 11, the clamping claw 72 is connected with a piston rod of the first air cylinder 71, and the first air cylinder 71 can drive the clamping claw 72 to perform clamping or loosening actions. The sampling bottle can be gripped or released by driving the gripping claw 72 by the first cylinder 71.

Further, the pipetting module 3 comprises a pump module and a liquid taking module, the pump module is fixedly arranged on the workbench 11 and is communicated with the liquid taking module, the liquid taking module is arranged on the third movement module 23 of the carrying module 2, and the pump module can transfer samples in the sample bottle 41 to the flaking bin module 9 through the liquid taking module and add buffer liquid to the flaking bin module 9. Through above-mentioned setting, can realize that sample liquid is automatic to be shifted, through controlling the pump assembly moreover, can guarantee accurate liquid removal volume.

Further, the pump assembly comprises a liquid pump 31 and a liquid injection pump 32, the liquid taking assembly comprises a pipette 33, a first conduit and a second conduit, the pipette 33 is arranged on the carrying assembly 2, the first conduit and the second conduit are arranged in the pipette 33, one end of the first conduit is communicated with the liquid pump 31, and one end of the second conduit is communicated with the liquid injection pump 32. The liquid pump 31 transfers the sample to the tablet housing assembly 9 through the first conduit, and the liquid pump 32 injects the buffer into the corresponding tablet housing assembly 9. By the mode, the sample can be transferred.

Further, the carrying assembly 2 is provided with a lifting assembly, the lifting assembly is in transmission connection with the pipette 33, and the lifting assembly can drive the pipette 33 to lift in the vertical direction. Through setting up the lifting unit, can drive the pipette 33 motion to further expand the lift scope of pipette 33, thereby satisfy the requirement of pipetting. Specifically, in this embodiment, a belt wheel motor 34 is fixedly arranged on the carrying assembly 2, the belt wheel motor 34 drives a belt 35 to drive the assembly to move, the pipette 33 is connected with a belt 35 in the belt 35 drive assembly, and the belt 35 is driven to move by the belt wheel motor 34, so that the lifting movement of the pipette 33 is realized. In other embodiments, a lifting cylinder may be used, and the piston rod of the lifting cylinder is used to drive the pipette 33 to move, so that the lifting assembly is not excessively limited.

Further, the automatic liquid-based cell pelleter further comprises a guide assembly, the guide assembly comprises a sliding rail, a sliding block and a guide block 36, the sliding rail is fixedly arranged on the carrying assembly 2, the sliding block is arranged on the sliding rail in a sliding manner, the pipette 33 is arranged in the guide block 36 in a penetrating manner, and the pipette 33 is connected with the sliding block. By providing the guide assembly, the movement of the pipette 33 can be guided, so that the smoothness and accuracy of the movement of the pipette 33 are ensured, and the pipetting operation can be smoothly completed.

Further, the automatic liquid-based cell pelleter further comprises a support 5, a pipette tip 51 is arranged on the support 5, and the pipette 33 can be inserted into the pipette tip 51 and drive the pipette tip 51 to move. Specifically, in each pipetting process, the pipette 33 is inserted into a disposable pipette tip 51, the liquid pump 31 pumps sample liquid into the pipette tip 51 through the first conduit, then the sample liquid is pipetted into the slide-making bin assembly 9, the liquid pump 32 injects buffer liquid through the second conduit, and the lifting assembly drives the pipette 33 to move upwards, so that the pipette tip 51 falls off after collision with the guide block 36.

Further, go film-making storehouse subassembly 8 includes rotating electrical machines 81, driving motor 82 and second clamping jaw subassembly, and rotating electrical machines 81 sets up on workstation 11, and rotating electrical machines 81 is connected with the driving motor 82 transmission, and driving motor 82 is connected with the second clamping jaw subassembly transmission, and rotating electrical machines 81 can drive the second clamping jaw subassembly through driving motor 82 and rotate, and driving motor 82 can drive the second clamping jaw subassembly and open or press from both sides tight action. Specifically, the slide preparing bin assembly 9 comprises a supporting plate 92, a slide and a rubber cylinder 91, wherein the slide is fixed on the supporting plate 92 through the rubber cylinder 91, and the rubber cylinder 91 is in threaded connection with the supporting plate 92. After centrifugation is completed, the electric claw assembly 24 carries the slide preparation bin assembly 9 to the second clamping jaw assembly through the carrying assembly 2, the second clamping jaw assembly can clamp the supporting plate 92 under the drive of the driving motor 82, then the rotating motor 81 drives the second clamping jaw assembly to rotate, liquid in the rubber cylinder 91 is poured off, then the rubber cylinder 91 is screwed out by the electric claw assembly 24, and the slide is clamped by the electric claw assembly 24. In this embodiment, the second jaw assembly and the first jaw assembly 25 have the same structure, and are not described herein in detail.

Further, in order to ensure the cleaning of the slide-making bin assembly 9, to avoid the residual sample liquid on the slide, the pump assembly further comprises a cleaning pump, a third conduit is arranged in the pipette 33, the cleaning pump is communicated with the third conduit, after the liquid in the rubber cylinder 91 is poured out, the cleaning pump injects clear water into the rubber cylinder 91 for cleaning through the third conduit, and then the cleaning pump is poured out again, so that the cleaning of the slide is ensured.

Further, a waste port is formed in the workbench 11, and a waste barrel 12 communicated with the waste port is arranged on the frame 1. Specifically, the waste port is directly opposite the second jaw assembly, facilitating dumping of waste liquid and recycling of the disposable pipette tip 51.

It is to be understood that the above examples of the present utility model are provided for clarity of illustration only and are not limiting of the embodiments of the present utility model. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. Any modification, equivalent replacement, improvement, etc. which come within the spirit and principles of the utility model are desired to be protected by the following claims.

Claims (10)

1. An automated liquid-based cell pelleter comprising:

the device comprises a frame (1), wherein a workbench (11) is arranged on the frame (1);

a carrying assembly (2), the carrying assembly (2) being arranged on the workbench (11) and being movable in three-dimensional space;

-an electric jaw assembly (24), the electric jaw assembly (24) being arranged on the handling assembly (2);

an oscillator (4), the oscillator (4) being arranged on the table (11) for oscillating the sample bottle (41);

the clamping device (7) is fixedly arranged on the workbench (11) and can clamp the sample bottle (41), and the electric claw assembly (24) can remove the bottle cap of the sample bottle (41);

the centrifugal machine (6), the centrifugal machine (6) is arranged on the workbench (11), and the centrifugal machine (6) is provided with a flaking bin assembly (9);

a pipetting assembly (3), the pipetting assembly (3) being arranged on the handling assembly (2), the pipetting assembly (3) being capable of transferring liquid from the sample bottle (41) into the slide-making bin assembly (9);

go film-making storehouse subassembly (8), go film-making storehouse subassembly (8) to set up on workstation (11), accomplish the centrifugation film-making storehouse subassembly (9) can fix go on film-making storehouse subassembly (8), go film-making storehouse subassembly (8) can with liquid in film-making storehouse subassembly (9) is poured, electric claw subassembly (24) can take out the slide in film-making storehouse subassembly (9).

2. The automated liquid-based cell pelleter of claim 1, wherein the electrical jaw assembly (24) comprises a first motor, a second motor and a first jaw assembly (25), the first motor being disposed on the handling assembly (2), the first motor being in driving connection with the second motor, the second motor being in driving connection with the first jaw assembly (25), the first motor being capable of driving the first jaw assembly (25) in rotation by the second motor, the second motor being capable of driving the first jaw assembly (25) in an opening or clamping action.

3. The automatic liquid-based cell pelleter according to claim 1, wherein the clamping device (7) comprises a first air cylinder (71) and a clamping jaw (72), the first air cylinder (71) is fixedly arranged on the workbench (11), the clamping jaw (72) is connected with a piston rod of the first air cylinder (71), and the first air cylinder (71) can drive the clamping jaw (72) to perform clamping or loosening actions.

4. The automated liquid-based cell pelleter of claim 1, wherein the pipetting assembly (3) comprises a pump assembly and a pipetting assembly, the pump assembly being arranged on the table (11) and in communication with the pipetting assembly, the pipetting assembly being arranged on the handling assembly (2), the pump assembly being capable of transferring samples from the sample bottles (41) into the pelleter cartridge assembly (9) via the pipetting assembly and adding buffer at the pelleter cartridge assembly (9).

5. The automated liquid-based cell pelleter of claim 4 wherein the pump assembly comprises a liquid pump (31) and a liquid injection pump (32), the liquid extraction assembly comprises a pipette (33), a first conduit and a second conduit, the pipette (33) is disposed on the handling assembly (2), the first conduit and the second conduit are disposed in the pipette (33), and one end of the first conduit is in communication with the liquid pump (31) and one end of the second conduit is in communication with the liquid injection pump (32).

6. The automatic liquid-based cell pelleter according to claim 5, wherein a lifting assembly is arranged on the carrying assembly (2), the lifting assembly is in transmission connection with the pipette (33), and the lifting assembly can drive the pipette (33) to lift in the vertical direction.

7. The automated liquid-based cell pelleter of claim 6 further comprising a guide assembly comprising a slide rail, a slider and a guide block (36), the slide rail being fixedly disposed on the handling assembly (2), the slider being slidingly disposed on the slide rail, the pipette (33) being threaded into the guide block (36), and the pipette (33) being connected to the slider.

8. The automated liquid-based cell pelleter of claim 5, further comprising a stand (5), wherein a pipette tip (51) is provided on the stand (5), wherein the pipette (33) is insertable into the pipette tip (51) and moves the pipette tip (51).

9. The automatic liquid-based cell pelleter according to claim 1, wherein the pelleter removal bin assembly (8) comprises a rotating motor (81), a driving motor (82) and a second clamping jaw assembly, wherein the rotating motor (81) is arranged on the workbench (11), the rotating motor (81) is in transmission connection with the driving motor (82), the driving motor (82) is in transmission connection with the second clamping jaw assembly, the rotating motor (81) can drive the second clamping jaw assembly to rotate through the driving motor (82), and the driving motor (82) can drive the second clamping jaw assembly to perform opening or clamping actions.

10. The automatic liquid-based cell pelleter according to claim 9, wherein a waste port is formed in the workbench (11), and a waste barrel (12) communicated with the waste port is arranged on the frame (1).

Images