CN109374353A - Automatic sampling device for automatic analyzer - Google Patents

Automatic sampling device for automatic analyzer Download PDF

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Publication number
CN109374353A
CN109374353A CN201811615024.2A CN201811615024A CN109374353A CN 109374353 A CN109374353 A CN 109374353A CN 201811615024 A CN201811615024 A CN 201811615024A CN 109374353 A CN109374353 A CN 109374353A
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China
Prior art keywords
connecting column
vertical connecting
automatic
suction cylinder
sampling device
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CN201811615024.2A
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Chinese (zh)
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CN109374353B (en
Inventor
杨永俊
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Lepaien Shenzhen Biotechnology Co ltd
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Individual
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14Suction devices, e.g. pumps; Ejector devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14Suction devices, e.g. pumps; Ejector devices
    • G01N2001/1418Depression, aspiration
    • G01N2001/1427Positive displacement, piston, peristaltic

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  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hydrology & Water Resources (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a kind of automatic sampling devices for automatic analyzer, including multi-dimensional movement mechanism, it is provided with the vertical connecting column that translation motor, lifting motor, rotating electric machine drive in the multi-dimensional movement mechanism, is provided with molten cutter and liquid-transfering gun on the vertical connecting column;The molten cutter is the electric iron that end has tubular cutting head, the inclined bottom surface setting of the tubular cutting head;The liquid-transfering gun includes the suction cylinder being connected with vertical connecting column, it is socketed in the suction cylinder by pushing motor-driven piston rod, the dust collecter end being connected with suction cylinder is arranged with rubber holding block, and the rubber holding block is the inverted cone-shaped structure that top tape has limit baffle.The configuration of the present invention is simple, easy to use, safety non-pollution meet the work pace that automatic analyzer carries out the requirement of batch detection and automatically analyzed.

Description

Automatic sampling device for automatic analyzer
Technical field
The present invention relates to liquid-transfering gun automatic sampling technical fields, more particularly, to a kind of taking automatically for automatic analyzer Sampling device.
Background technique
Artificial suction sample is mostly used to match the analysis for carrying out sample with analyzer at present.It is existing with plastics screw cap Sample bottle is when being sampled, and generally by artificial twist-off closure, then carries out taking liquid by liquid-transfering gun.Above-mentioned sample bottle is mating automatic Bottle cap need to all be removed in use, if still using above-mentioned sampling method and be put into analyzer, be moved through in sample bottle by analyzer There are the risks that bottle body is toppled in journey or sampling process;It is exactly to integrate to melt in automatic analyzer to cut dress that another, which is imagined, It sets, i.e., first melts cut-out hole on bottle cap, be then sampled, can be poured down or forth in this way to avoid liquid again.But it is cut using existing melt When device, the cut-out meeting nature of bottle cap is fallen in bottle body, and sample is caused to pollute.Secondly, cross-infection in order to prevent, each Detection sample is both needed to match a liquid-transfering gun pipette tips, i.e., needs to carry out pipette tips replacement before liquid-transfering gun takes liquid.Current shifting Liquid rifle mostly uses manually installed pipette tips, liquid sucking-discharging and unloading pipette tips, when sample size is more, need to expend more time and Energy;Secondly, sample is easy to happen pollution, influences the accuracy of testing result when operating lack of standardization;Again, using artificial Operation liquid-transfering gun is matched with automatic analyzer, it is clear that is unpractical.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of automatic sampling device for automatic analyzer, particular technique Scheme is as follows:
Automatic sampling device of the present invention for automatic analyzer, including multi-dimensional movement mechanism, the multi-dimensional movement machine It is provided with the vertical connecting column that translation motor, lifting motor, rotating electric machine drive on structure, is arranged on the vertical connecting column There are molten cutter and liquid-transfering gun;The molten cutter is the electric iron that end has tubular cutting head, the bottom surface of the tubular cutting head It is obliquely installed;The liquid-transfering gun includes the suction cylinder being connected with vertical connecting column, is socketed in the suction cylinder by pushing electricity The piston rod of machine driving, the dust collecter end being connected with suction cylinder are arranged with rubber holding block, and the rubber holding block is top Inverted cone-shaped structure of the portion with limit baffle.
The multi-dimensional movement mechanism includes vertical plate, and sliding is provided with mobile framework in the horizontal direction on the vertical plate, described Mobile framework is connected with the ball-screw that the translation motor drives, and the lifting motor is provided on the top plate of mobile framework, Sliding is provided with lifter plate in mobile framework, and the lifter plate is connected with the ball-screw that lifting motor drives, sets on lifter plate It is equipped with the rotating electric machine, rotating electric machine is connected by synchronous belt mechanism with the vertical connecting column, and vertical connecting column, which passes through, to be moved The bottom plate of dynamic frame simultaneously extends downwardly.
The inclined surface of the tubular cutting head and the angle of horizontal plane are 30-60 °.
Pushing column is provided in the tubular cutting head, the bottom for pushing column and tubular cutting head is coplanar with.
It is provided with pilot sleeve between the suction cylinder and vertical connecting column, the pushing is provided in the pilot sleeve The feed screw nut of motor-driven ball-screw, the ball screw is connected with push strut, is arranged from top to bottom outside pilot sleeve There are plug-in card plate, upper clip and the lower clip for fixing suction cylinder, the piston rod is connected by push plate with the push strut.
The upper clip is identical with the structure of lower clip, includes the left jamming claw being hinged and connected with the pilot sleeve and the right side Claw, and the left and right claw is connected by return spring.
The configuration of the present invention is simple, easy to use, safety non-pollution melt cutter and shifting under the action of multi-dimensional movement mechanism Liquid rifle can work alternately, and first melt to sample bottle cap and cut, then carries out aspirated liquid from sample bottle, meanwhile, liquid-transfering gun exists Under the mating reaction of pipette tips erector and pipette tips emptier, it can also realize the automatic replacement of pipette tips, meet automatic analyzer The work pace for carrying out the requirement of batch detection and being automatically analyzed.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention.
Fig. 2 is the structural schematic diagram that cutter is melted in Fig. 1.
Specific embodiment
As shown in Figure 1, the automatic sampling device of the present invention for automatic analyzer, including there is translation, lifting With the multi-dimensional movement mechanism of rotation function and coupled molten cutter and liquid-transfering gun.
Specifically, above-mentioned multi-dimensional movement mechanism includes vertical plate 1.1, is slidably fitted with movement in the horizontal direction on vertical plate 1.1 Frame 1.2, mobile framework 1.2 are connected with the ball-screw that translation motor 1.3 drives, are equipped on the top plate of mobile framework 1.2 Lifting motor 1.4 is slidably fitted with lifter plate 1.5, the ball that lifter plate 1.5 and lifting motor 1.4 drive in mobile framework 1.2 Lead screw is connected, and rotating electric machine 1.6 is equipped on lifter plate 1.5, and rotating electric machine 1.6 passes through synchronous belt mechanism and vertical connecting column 1.7 are connected, and vertical connecting column 1.7 passes through the bottom plate of mobile framework 1.2 and extends downwardly.Therefore, which can be with Realize translation, lifting and rotation function.
Vertical 1.7 side of connecting column is connected with molten cutter, which is that end is ironed with the electricity of tubular cutting head 2.1 Iron, the inclined bottom surface setting of the tubular cutting head 2.1, forms the scarf that angle with horizontal plane is 30-60 °.Further, cylinder It is equipped in shape cutting head 1 and pushes column 2.2 made of non-thermally conductive material, the bottom of the pushing column 2.2 and tubular cutting head 2.1 is total The bottom surface of face setting, i.e. pushing column 2.2 is identical as the bottom surface gradient of tubular cutting head 2.1.
Vertical 1.7 other side of connecting column is connected with the liquid-transfering gun that suction cylinder 3.1, piston rod 3.2 and dust collecter 3.3 form. Specifically, pilot sleeve 3.4 is installed on vertical connecting column 1.7, is equipped in pilot sleeve 3.4 and pushes what motor 3.5 drove The feed screw nut of ball-screw, ball screw is connected with push strut 3.6, is equipped with plug-in card plate outside pilot sleeve 3.4 from top to bottom 3.7, upper clip 3.8 and lower clip 3.9, the plug-in card plate 3.7, upper clip 3.8 and lower clip 3.9 are connected with suction cylinder 3.1, living Stopper rod 3.2 is connected by push plate 3.10 with push strut 3.6.3.3 end of dust collecter is arranged with for connecting liquid-transfering gun pipette tips Rubber holding block 3.11, the rubber holding block 3.11 are the inverted cone-shaped structure that top tape has limit baffle.Above-mentioned 3.8 He of upper clip The structure of lower clip 3.9 is identical, includes the left jamming claw and right jamming claw being hinged and connected with pilot sleeve 3.4, and left and right claw is logical It crosses return spring to be connected, so as to clamp the liquid-transfering gun of different model (referring to that suction cylinder outer diameter is different).
Under normal conditions, the present invention is used cooperatively with pipette tips erector, pipette tips emptier.Above-mentioned pipette tips erector is using general Lead to commercially available pipette tips box or other structures, pipette tips emptier includes collection box and the pipette tips snap-gauge that is disposed thereon.It is transported in multidimensional Under the action of motivation structure, liquid-transfering gun is moved to above pipette tips erector, and dust collecter 3.3 is aligned after disposable pipette tips are open to lower fortune It is dynamic, it is socketed in pipette tips on the rubber holding block 3.11 of dust collecter 1;Later, molten cutter and liquid-transfering gun are alternately moved into sample bottle Top, first progress bottle cap is molten cuts, then carries out sample suction, and the sample in liquid-transfering gun is then injected into specimen cup etc. and analysis again In the matched liquid storage container of instrument;Finally, liquid-transfering gun is moved at the pipette tips snap-gauge of pipette tips emptier, and make pipette tips upper surface and rifle Head snap-gauge lower surface is in contact, and then, is lifted dust collecter 3.3, separates pipette tips with rubber holding block 3.11.So far, one is completed Secondary automatic sampling work.
Above-mentioned bottle cap is molten, and to cut through journey specific as follows: being first powered makes electric iron reach set temperature, then makes tubular cutting head 2.1 carry out molten cut to sample bottle cap straight down.Since the bottom of tubular cutting head 2.1 is scarf, on the lower One end is first in contact melt with bottle cap and cut, and the bottle cap other end is still connected with bottle cap body;With tubular cutting head 2.1 constantly to Lower passage, the cutting contour on bottle cap gradually extend, and are moved down under the action of pushing column 2.2 and bottle cap by cut portion Main body separation, forms the suction hole passed through for liquid-transfering gun pipette tips.In order to avoid the molten root for cutting part is thoroughly divided with bottle cap body From causing molten slice to fall in sample bottle, it is molten cut terminal when, the scarf highest point of tubular cutting head 2.1 is still needed in bottle It is more than lid.

Claims (6)

1. a kind of automatic sampling device for automatic analyzer, it is characterised in that: including multi-dimensional movement mechanism, the multidimensional fortune Be provided on motivation structure translation motor, lifting motor, rotating electric machine driving vertical connecting column, on the vertical connecting column It is provided with molten cutter and liquid-transfering gun;The molten cutter is the electric iron that end has tubular cutting head, the tubular cutting head Inclined bottom surface setting;The liquid-transfering gun includes the suction cylinder being connected with vertical connecting column, is socketed in the suction cylinder by pushing away The piston rod of Medium-voltage Motor driving, the dust collecter end being connected with suction cylinder is arranged with rubber holding block, the rubber holding block There is the inverted cone-shaped structure of limit baffle for top tape.
2. the automatic sampling device according to claim 1 for automatic analyzer, it is characterised in that: the multi-dimensional movement Mechanism includes vertical plate, and sliding is provided with mobile framework, the mobile framework and translation electricity in the horizontal direction on the vertical plate The ball-screw of machine driving is connected, and the lifting motor is provided on the top plate of mobile framework, and sliding is provided in mobile framework Lifter plate, the lifter plate are connected with the ball-screw that lifting motor drives, and the rotating electric machine is provided on lifter plate, rotation Motor is connected by synchronous belt mechanism with the vertical connecting column, vertical connecting column across mobile framework bottom plate and to downward It stretches.
3. the automatic sampling device according to claim 1 for automatic analyzer, it is characterised in that: the tubular cutting The inclined surface of head and the angle of horizontal plane are 30-60 °.
4. the automatic sampling device according to claim 1 for automatic analyzer, it is characterised in that: the tubular cutting Pushing column is provided in head, the bottom for pushing column and tubular cutting head is coplanar with.
5. the automatic sampling device according to claim 1 for automatic analyzer, it is characterised in that: the suction cylinder and It is provided with pilot sleeve between vertical connecting column, the motor-driven ball-screw of pushing is provided in the pilot sleeve, The feed screw nut of the ball screw is connected with push strut, is provided with from top to bottom outside pilot sleeve for fixing inserting for suction cylinder Snap-gauge, upper clip and lower clip, the piston rod are connected by push plate with the push strut.
6. the automatic sampling device according to claim 5 for automatic analyzer, it is characterised in that: the upper clip and The structure of lower clip is identical, includes the left jamming claw and right jamming claw being hinged and connected with the pilot sleeve, and the left and right claw It is connected by return spring.
CN201811615024.2A 2018-12-27 2018-12-27 Automatic sampling device for automatic analyzer Active CN109374353B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111235031A (en) * 2020-03-11 2020-06-05 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Intelligent semen optimization system
CN111346682A (en) * 2020-03-11 2020-06-30 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Liquid accurate suction proportioning system
CN111514952A (en) * 2020-05-14 2020-08-11 广东体必康生物科技有限公司 Pipetting device and method capable of self-checking air tightness and accurately extracting
CN114279978A (en) * 2021-12-29 2022-04-05 南京祥中生物科技有限公司 Novel full-automatic detection and analysis workstation
CN115569680A (en) * 2022-10-11 2023-01-06 成都迪安医学检验所有限公司 Magnetic force controllable type ceiling type pipettor

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111235031A (en) * 2020-03-11 2020-06-05 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Intelligent semen optimization system
CN111346682A (en) * 2020-03-11 2020-06-30 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Liquid accurate suction proportioning system
CN111235031B (en) * 2020-03-11 2023-04-07 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Intelligent semen optimization system
CN111514952A (en) * 2020-05-14 2020-08-11 广东体必康生物科技有限公司 Pipetting device and method capable of self-checking air tightness and accurately extracting
CN114279978A (en) * 2021-12-29 2022-04-05 南京祥中生物科技有限公司 Novel full-automatic detection and analysis workstation
CN115569680A (en) * 2022-10-11 2023-01-06 成都迪安医学检验所有限公司 Magnetic force controllable type ceiling type pipettor
CN115569680B (en) * 2022-10-11 2023-08-29 成都迪安医学检验所有限公司 Magnetic force controllable ceiling type pipettor

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Effective date of registration: 20240226

Address after: 323-K, 3rd Floor, Comprehensive Xinxing Phase I, No.1 Haihong Road, Fubao Community, Fubao Street, Futian District, Shenzhen City, Guangdong Province, 518000

Patentee after: Lepaien (Shenzhen) Biotechnology Co.,Ltd.

Country or region after: China

Address before: No. 3, Building 3, Yard 25, Jingwu Road, Jinshui District, Zhengzhou City, Henan Province, 450000

Patentee before: Yang Yongjun

Country or region before: China