CN109336950A - A kind of magnetic frame - Google Patents
A kind of magnetic frame Download PDFInfo
- Publication number
- CN109336950A CN109336950A CN201811407913.XA CN201811407913A CN109336950A CN 109336950 A CN109336950 A CN 109336950A CN 201811407913 A CN201811407913 A CN 201811407913A CN 109336950 A CN109336950 A CN 109336950A
- Authority
- CN
- China
- Prior art keywords
- test tube
- hole
- permanent magnet
- magnetic
- rack
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000005291 magnetic effect Effects 0.000 title claims abstract description 156
- 238000012360 testing method Methods 0.000 claims abstract description 155
- 239000011324 bead Substances 0.000 claims abstract description 29
- 239000011859 microparticle Substances 0.000 claims abstract description 21
- 238000004220 aggregation Methods 0.000 claims abstract description 7
- 230000002776 aggregation Effects 0.000 claims abstract description 7
- 238000004140 cleaning Methods 0.000 abstract description 5
- BGPVFRJUHWVFKM-UHFFFAOYSA-N N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] Chemical compound N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] BGPVFRJUHWVFKM-UHFFFAOYSA-N 0.000 description 36
- 238000010586 diagram Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000005389 magnetism Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000003463 adsorbent Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- -1 antibody Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 230000005298 paramagnetic effect Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Abstract
The present invention relates to biological device fields, disclose a kind of magnetic frame, including rack for test tube component, and the rack for test tube component is provided with the test tube hole for inserting test tube, is additionally provided with through-hole in the middle part of the rack for test tube component；Permanent magnet is rotatablely installed in the through-hole, the permanent magnet is used to the invisible spectro magnetic bead microparticle aggregation being adsorbed on the test tube tube wall.Magnetic frame provided by the invention realizes the switch in magnetic frame magnetic field by rotation permanent magnet, simple to operate, and cleaning release magnetic bead need to only rotate permanent magnet, time saving and energy saving.
Description
Technical field
The present invention relates to biological device fields, more particularly to a kind of magnetic frame.
Background technique
It is obtained in the technology of liquid phase separation large biological molecule on biomedical boundary using super paramagnetic beads microparticle and is answered extensively
With, such as protein isolate matter, antibody and nucleic acid.After the solution containing magnetic bead microparticle is put into test tube, in the feelings of not magnetic force
Under condition, magnetic bead microparticle can be distributed in the solution after agitation；But when the test tube is placed in the magnetic field of some strength, superparamagnetic
Magnetic bead microparticle is magnetized while being attracted to the strongest position in magnetic field and being gathered into closely one on test tube wall.
It is integrated inseparable structure that existing magnetic frame product, which is largely magnet with rack for test tube, is needed common
The stirring of magnetic bead microparticle is completed on rack for test tube, uniformly mixes, adsorb the operation of substance to be separated, and is completed on existing magnetic frame
The aggregation operator of magnetic bead microparticle, user need to be repeated several times one by one transfer of the test tube between magnetic frame and common test tube frame.?
There is the magnetic frame of some split type structures, but needs being dismounted for multiple times, it is cumbersome, it expends the time and is easily damaged magnetic frame.
Summary of the invention
(1) technical problems to be solved
The object of the present invention is to provide a kind of easy to operate, time saving and energy saving, the magnetic force of magnetic bead microparticle in test tube is acted on
The magnetic frame that can be opened and closed or close.
(2) technical solution
In order to solve the above technical problem, the present invention provides a kind of magnetic frame, including rack for test tube component, the rack for test tube group
Part is provided with the test tube hole for inserting test tube, is additionally provided with through-hole in the middle part of the rack for test tube component；Rotation peace in the through-hole
Permanent magnet is filled, the permanent magnet is used to the invisible spectro magnetic bead microparticle aggregation being adsorbed on the test tube tube wall.
It wherein, further include magnetizer, the magnetizer is parallel to the axis setting of the test tube hole, is fixedly installed in described
Through-hole end, the permanent magnet and the magnetizer are rotatablely connected.
Wherein, the axis of the through-hole is arranged perpendicular to the axis of the test tube hole, and the surfaces of revolution of the permanent magnet is vertical
In the axis of the through-hole, the two poles of the earth line radially extending along the through-hole of the permanent magnet.
Wherein, the rack for test tube component has multiple, multiple rack for test tube components along the through-hole axis direction sequentially
It is connected.
Wherein, the rack for test tube component is symmetrical arranged in the through-hole two sides there are two the test tube hole.
Wherein, the opposite two sides of the rack for test tube component are correspondingly arranged on the first protrusion and the first groove, described in one
First protrusion of rack for test tube component is connected with first groove of rack for test tube component described in another.
Wherein, the permanent magnet side be provided with second protrusion and the second groove, described the second of a permanent magnet
Protrusion is connected with the second groove of permanent magnet described in another.
Wherein, the test tube hole is slotted eye, and the minor axis length of section ellipse is 9.5-10.5mm, long axis and short axle
Length ratio be 1.2-1.4.
Wherein, the test tube hole aperture is provided with boss.
Wherein, there are two the boss of each test tube hole aperture setting, the height of the boss is 1-5mm, institute
The width for stating boss is 1-3mm.
(3) beneficial effect
Magnetic frame provided by the invention, permanent magnet are installed in rack for test tube component, can be made forever by the rotation of permanent magnet
The magnetic pole of magnet is close to or far from the test tube inserted in test tube hole.When the magnetic pole of permanent magnet rotate to far from test tube position when,
The magnetic line of force across test tube is more sparse, and magnetic frame can consider in magnetic force closed state, and can be used as common test tube
Frame uses, and testing crew is made to eliminate the complex operations for shifting test tube back and forth, one by one between rack for test tube and common magnetic frame.When
When the magnetic pole of permanent magnet is rotated to close to the position of test tube, the magnetic line of force intensively passes through test tube, and magnetic bead microparticle is in stronger magnetic
In, can be attracted to the strongest position in magnetic field while magnetic bead microparticle is magnetized and with the immediate examination of permanent magnet pole
Close one is gathered on tube wall；At this point, magnetic frame is in the folding condition of magnetic force load, it can be washed, be purified
Operation.The magnetic frame of the embodiment of the present invention realizes the switch in magnetic frame magnetic field by rotation permanent magnet, simple to operate, clearly
Permanent magnet need to only be rotated by washing release magnetic bead, time saving and energy saving.
Detailed description of the invention
Fig. 1 is magnetic frame of embodiment of the present invention schematic perspective view；
Fig. 2 is magnetic frame of embodiment of the present invention magnetic force folding condition schematic diagram；
Fig. 3 is magnetic frame of embodiment of the present invention magnetic force closed mode schematic diagram；
Fig. 4 is rack for test tube of embodiment of the present invention component schematic perspective view；
Fig. 5 is permanent magnet of the embodiment of the present invention and magnetizer structure schematic diagram；
Permanent magnet and magnetizer schematic cross-section when Fig. 6 is magnetic frame of embodiment of the present invention magnetic force closed state；
In figure: 1, rack for test tube component；2, test tube hole；3, through-hole；4, permanent magnet；5, magnetizer；6, test tube；7, the magnetic line of force；
8, boss；9, knob；10, the first groove；11, the first protrusion；12, the second protrusion；13, magnetic bead aggregation；14, magnetic conduction face.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Implement below
Example is not intended to limit the scope of the invention for illustrating the present invention.
In the description of the present invention, it should be noted that term " center ", " longitudinal direction ", " transverse direction ", "upper", "lower",
The orientation or positional relationship of the instructions such as "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", "outside" is
It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description of the present invention and simplification of the description, rather than instruction or dark
Show that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as pair
Limitation of the invention.In addition, term " first ", " second ", " third " etc. are used for description purposes only, and should not be understood as instruction or
Imply relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can
To be mechanical connection, it is also possible to be electrically connected；It can be directly connected, can also can be indirectly connected through an intermediary
Connection inside two elements.For the ordinary skill in the art, concrete condition can be regarded and understand that above-mentioned term exists
Concrete meaning in the present invention.
In addition, in the description of the present invention, unless otherwise indicated, " multiple ", " more ", " multiple groups " be meant that two or
It is more than two.
As shown in figures 1 to 6, the magnetic frame of the embodiment of the present invention, including rack for test tube component 1, rack for test tube component 1 are arranged useful
Through-hole 3 is additionally provided in the middle part of the test tube hole 2 for inserting test tube 6, rack for test tube component 1；Permanent magnet 4 is rotatably equipped in through-hole 3, forever
Magnet 4 is used to the magnetic bead microparticle aggregation in test tube 6 being adsorbed on 6 side wall of test tube.
The magnetic frame of the embodiment of the present invention, permanent magnet 4 can pass through permanent magnetism in being installed in the through-hole 3 of rack for test tube component 1
The rotation of body 4 makes the magnetic pole of permanent magnet 4 close to or far from the test tube 6 inserted in test tube hole 2.Magnetic bead is placed in solution in test tube 6
Microparticle, protein, antibody, nucleotide of the magnetic bead microparticle in adsorbent solution wait separate substance.When the magnetic of permanent magnet 4
Pole rotate to far from test tube 6 position when, the magnetic line of force 7 across test tube 6 is more sparse, and magnetic bead microparticle dispersed distribution is in solution
In；By agitating solution, magnetic bead microparticle can be made preferably to adsorb substance to be separated, magnetic frame can consider in magnetic at this time
Power closed state, magnetic frame can be used as common rack for test tube and use, and eliminate testing crew in rack for test tube and common magnetic force
The complex operations of test tube 6 are shifted between frame back and forth, one by one.When the magnetic pole of permanent magnet 4 is rotated to close to the position of test tube 6, magnetic
The line of force 7 intensively passes through test tube 6, and magnetic bead microparticle is in stronger magnetic field, can be attracted while magnetic bead microparticle is magnetized
To the strongest position in magnetic field and be gathered into close one on immediate 6 tube wall of test tube of 4 magnetic pole of permanent magnet, form magnetic bead
Aggregation 13；At this point, magnetic frame is in the folding condition of magnetic force load, it the operation such as can be washed, be purified.It is more compared to needing
Secondary dismounting, cumbersome time-consuming and easy to damage detachable magnetic frame, the magnetic frame of the embodiment of the present invention, by rotating permanent magnet 4
Realize the switch of magnetic frame magnetic force, simple to operate, cleaning release magnetic bead need to only rotate permanent magnet 4, time saving and energy saving.
Connection 4 the two poles of the earth of permanent magnet can be set in magnetic field strength when in order to further weaken magnetic force closed state in test tube 6
Magnetizer 5, make permanent magnet 4 issue the magnetic line of force 7 by magnetizer 5 formed closed circuit, thus the magnetic that permanent magnet 4 is issued
The line of force 7 constrains in 5 range of magnetizer, reduces the magnetic force leakage of permanent magnet 4.Magnetizer 5 can be parallel to the axis of test tube hole 2
Setting, is fixedly installed in the end of through-hole 3, and permanent magnet 4 and magnetizer 5 are rotation connection.When permanent magnet 4 rotation to be parallel to examination
When 2 axis direction of pore, 4 liang of magnetic poles of permanent magnet are far from 6 tube wall of test tube, while two magnetic poles of permanent magnet 4 are close to magnetizer 5, magnetic
Power frame is in magnetic force closed state.For example, magnetizer 5 can be U-shaped, the both ends of U-shaped are to fit with the both ends of permanent magnet 4
Magnetic conduction face 14, when the rotation of permanent magnet 4 is to when being parallel to 2 axis direction of test tube hole, two magnetic poles far from 6 tube wall of test tube, 4 liang of permanent magnet
It holds the magnetic line of force 7 of magnetic pole that can pass through magnetic conduction face 14 and closed circuit is formed by magnetizer 5.In order to make test tube 6 with vertical shape
State inserts in test tube hole 2, and the axis of test tube hole 2, which can be, to be vertically arranged.The axis of the through-hole 3 of rack for test tube component 1 can be with
Be it is horizontally disposed with 2 axis perpendicular of test tube hole, the surfaces of revolution that permanent magnet 4 rotates in through-hole 3 mutually hangs down with 3 axis of through-hole
Directly, permanent magnet 4 can be strip, line the radially extending along through-hole 3 at north and south the two poles of the earth.Through-hole 3 can be circle, can also
To be oval.When permanent magnet 4 turns to horizontal position, 4 magnetic pole of permanent magnet and 6 tube wall of test tube have minimum distance, magnetic force
Frame is in the folding condition of magnetic force load；When permanent magnet 4 turns to vertical position, 4 magnetic pole of permanent magnet has with 6 tube wall of test tube
Maximum distance, magnetic frame are in magnetic force closed state.Magnetizer 5 can be vertically arranged, and permanent magnet 4 turns to vertical position
When, the magnetic pole at 4 both ends of permanent magnet fits with the magnetic conduction face 14 of magnetizer 5, further weakens the magnetic field strength in test tube 6.
The rack for test tube component 1 that the magnetic frame of the embodiment of the present invention can be equipped with fixed quantity test tube hole by one forms,
It can be and be made of the rack for test tube component 1 that multiple axis directions along through-hole 3 are sequentially connected, each rack for test tube component 1 can be
3 two sides of through-hole are symmetrical arranged two test tube holes 2.In this way, user can need to assemble the rack for test tube group of different number according to test
Part 1 is magnetic frame, to insert the different test tube 6 of quantity while be operated.Rack for test tube component 1 front and back connection can by
Its opposite front and rear sides face is correspondingly arranged the first protrusion 11 and the first groove 10 is realized, the first of a rack for test tube component 1 is convex
11 are played to be connected together with the first groove 10 of another rack for test tube component 1.The second protrusion 12 has can be set in the side of permanent magnet 4
With the second groove, the permanent magnet 4 being installed in 1 through-hole 3 of a rack for test tube component by its second protrusion 12 be installed on it is another
Second groove of the permanent magnet 4 in a 1 through-hole 3 of rack for test tube component is connected together, and realizes that the front and back connection of permanent magnet 4 and rotation pass
It passs.A knob 9 can be installed in the rack for test tube component 1 for being set to magnetic frame one end, knob 9 is installed on rack for test tube component 1
It is connected at through-hole 3 and with the second protrusion 12 of permanent magnet 4 or the second groove, permanent magnetism of the embodiment of the present invention is rotated by knob 9
The rotation of body 4, it is simple and convenient.
The test tube hole 2 of the embodiment of the present invention can be slotted eye, and the minor axis length of section ellipse can be slightly less than city
The minimum value that test tube 6 is commonly used on field generates a small amount of deformation, generated extruding and frictional force after so that test tube 6 is inserted into slotted eye
The firm fixation of test tube 6 can be made to insert in test tube hole 2；Even if oval long axis makes test tube, 6 tolerance is larger, can also by compared with
Small deformation inserts in test tube hole 2, is unlikely to the situation that cylinder is easy under locking disassembly not with circular hole occur.Short axle can be
The length ratio of 9.5-10.5mm, long axis and short axle is 1.2-1.4.Such as the section ellipse short shaft that test tube hole 2 can be set is
10.5mm, long axis 11.5mm.Make test tube 6 and the more firm fixation of magnetic frame by the way that slotted eye is arranged, allows user
Test tube 6 and magnetic frame such as are overturned as a whole, tilt, rotate, shakes at operation, the completion and overturns mixing, make magnetic bead and
Solution comes into full contact with, and guarantees the quality of absorption or cleaning, further increases the operation homogeneity between working efficiency and test tube 6.
In addition, boss 8 has can be set in the orifice edge of test tube hole 2, thus after test tube 6 is inserted into test tube hole 2, the side of 6 nozzle of test tube
It keeps being unlikely to fit closely, facilitating and pick and place test tube 6 not less than at a distance from 8 height of boss along with the vent surface of test tube hole 2.
The boss 8 of each 2 aperture of test tube hole setting can there are two, the height of boss 8 can be 1-5mm, and the width of boss 8 can be
1-3mm.For example, can be 1.5mm in the 2 short axle both ends of test tube hole of ellipse setting height, the boss 8 that width is 3mm.
As can be seen from the above embodiments, magnetic frame provided by the invention, permanent magnet 4 are installed in rack for test tube component 1, energy
Enough make the magnetic pole of permanent magnet 4 close to or far from the test tube 6 inserted in test tube hole 2 by the rotation of permanent magnet 4.When permanent magnet 4
Magnetic pole rotate to far from test tube 6 position when, the magnetic line of force 7 across test tube 6 is more sparse, and magnetic frame can consider in magnetic force
Closed state, and can be used as common rack for test tube and use, eliminate testing crew between rack for test tube and common magnetic frame
One by one, the complex operations of test tube 6 are shifted back and forth.When the magnetic pole of permanent magnet 4 is rotated to close to the position of test tube 6, the magnetic line of force 7 is close
Across test tube 6, magnetic bead microparticle is in stronger magnetic field collection, can be attracted to magnetic field most while magnetic bead microparticle is magnetized
Strong position and be gathered into close one on immediate 6 tube wall of test tube of 4 magnetic pole of permanent magnet；At this point, magnetic frame is in
The folding condition of magnetic force load, the operation such as can be washed, be purified.Magnetic frame of the present invention realizes magnetic force by rotation permanent magnet 4
The switch in frame magnetic field, simple to operate, cleaning release magnetic bead need to only rotate permanent magnet 4, time saving and energy saving.In order to further
Magnetic field strength when weakening magnetic force closed state in test tube 6 can be set the magnetizer 5 at connection 4 the two poles of the earth of permanent magnet, make permanent magnet
4 magnetic lines of force 7 issued form closed circuit by magnetizer 5, so that the magnetic line of force 7 that permanent magnet 4 issues is constrained in magnetizer 5
In range, the magnetic force leakage of permanent magnet 4 is reduced.Magnetic frame of the present invention can by before and after multiple rack for test tube components 1 connect combination and
At it is magnetic frame that user can need to assemble the rack for test tube component 1 of different number according to test, to insert the different test tube of quantity
6 are operated simultaneously.Further, the test tube hole 2 of magnetic frame of the present invention can be set to slotted eye, make test tube 6 and magnetic frame
More firm fixation allows user the test tube 6 and magnetic frame such as to overturn, tilt, rotate, shake as a whole and grasps
Make, mixing is overturned in completion, comes into full contact with magnetic bead with solution, guarantees the quality of absorption or cleaning, further increases work effect
Operation homogeneity between rate and test tube 6.In addition, boss 8 has can be set in the orifice edge of test tube hole 2, facilitates and pick and place test tube 6.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of magnetic frame, which is characterized in that including rack for test tube component, the rack for test tube component is provided with for inserting test tube
Test tube hole, the rack for test tube component middle part are additionally provided with through-hole；Permanent magnet is rotatablely installed in the through-hole, the permanent magnet is used for
The invisible spectro magnetic bead microparticle aggregation is adsorbed on the test tube tube wall.
2. magnetic frame according to claim 1, which is characterized in that further include magnetizer, the magnetizer is parallel to described
The axis of test tube hole is arranged, and is fixedly installed in the through-hole end, and the permanent magnet and the magnetizer are rotatablely connected.
3. magnetic frame according to claim 2, which is characterized in that axis of the axis of the through-hole perpendicular to the test tube hole
Line setting, the surfaces of revolution of the permanent magnet is perpendicular to the axis of the through-hole, and the two poles of the earth line of the permanent magnet is along the through-hole
Radially extend.
4. magnetic frame according to claim 1, which is characterized in that the rack for test tube component has multiple, multiple test tubes
Frame component is sequentially connected along the axis direction of the through-hole.
5. magnetic frame according to claim 4, which is characterized in that the rack for test tube component is symmetrically set in the through-hole two sides
The test tube hole there are two setting.
6. magnetic frame according to claim 4, which is characterized in that the opposite two sides of the rack for test tube component are correspondingly arranged
There are the first protrusion and the first groove, first protrusion and another rack for test tube component of a rack for test tube component
First groove is connected.
7. magnetic frame according to claim 4, which is characterized in that the permanent magnet side is provided with the second protrusion and second
Second protrusion of groove, a permanent magnet is connected with the second groove of permanent magnet described in another.
8. magnetic frame according to claim 1, which is characterized in that the test tube hole is slotted eye, section ellipse
Minor axis length is 9.5-10.5mm, and the length ratio of long axis and short axle is 1.2-1.4.
9. magnetic frame according to claim 1, which is characterized in that the test tube hole aperture is provided with boss.
10. magnetic frame according to claim 9, which is characterized in that the boss of each test tube hole aperture setting
There are two, the height of the boss is 1-5mm, and the width of the boss is 1-3mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811407913.XA CN109336950A (en) | 2018-11-23 | 2018-11-23 | A kind of magnetic frame |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811407913.XA CN109336950A (en) | 2018-11-23 | 2018-11-23 | A kind of magnetic frame |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109336950A true CN109336950A (en) | 2019-02-15 |
Family
ID=65317645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811407913.XA Pending CN109336950A (en) | 2018-11-23 | 2018-11-23 | A kind of magnetic frame |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109336950A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020192090A1 (en) * | 2019-03-27 | 2020-10-01 | 苏州长光华医生物医学工程有限公司 | Kit storage rack preventing magnetic particle deposition |
| CN113088430A (en) * | 2021-04-09 | 2021-07-09 | 广州新成生物科技有限公司 | Rotary magnetic attraction device |
| CN116419699A (en) * | 2021-11-10 | 2023-07-11 | 飞利浦家电控股有限公司 | Kitchen appliance |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204434596U (en) * | 2015-01-13 | 2015-07-01 | 河南赛诺特生物技术有限公司 | A kind of magnetic frame extracting Nucleotide for paramagnetic particle method |
| CN205095460U (en) * | 2015-05-13 | 2016-03-23 | 上海快灵生物科技有限公司 | Magnetic bead reagent magnetization unit |
| CN105459141A (en) * | 2015-12-30 | 2016-04-06 | 华南理工大学 | Magnetic manipulator adopting magnetic frame principle |
| CN105665132A (en) * | 2014-11-20 | 2016-06-15 | 瀚吉康生物科技（北京）有限公司 | Combined type magnetic frame |
| CN206375924U (en) * | 2016-12-21 | 2017-08-04 | 北京擎科新业生物技术有限公司 | Nucleic acid purification magnetic frame |
| CN206683922U (en) * | 2017-08-07 | 2017-11-28 | 广州市达瑞生物技术股份有限公司 | A kind of tubular type magnetic bead separating device |
-
2018
- 2018-11-23 CN CN201811407913.XA patent/CN109336950A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105665132A (en) * | 2014-11-20 | 2016-06-15 | 瀚吉康生物科技（北京）有限公司 | Combined type magnetic frame |
| CN204434596U (en) * | 2015-01-13 | 2015-07-01 | 河南赛诺特生物技术有限公司 | A kind of magnetic frame extracting Nucleotide for paramagnetic particle method |
| CN205095460U (en) * | 2015-05-13 | 2016-03-23 | 上海快灵生物科技有限公司 | Magnetic bead reagent magnetization unit |
| CN105459141A (en) * | 2015-12-30 | 2016-04-06 | 华南理工大学 | Magnetic manipulator adopting magnetic frame principle |
| CN206375924U (en) * | 2016-12-21 | 2017-08-04 | 北京擎科新业生物技术有限公司 | Nucleic acid purification magnetic frame |
| CN206683922U (en) * | 2017-08-07 | 2017-11-28 | 广州市达瑞生物技术股份有限公司 | A kind of tubular type magnetic bead separating device |
Non-Patent Citations (1)
| Title |
|---|
| 赵镛浩: "热处理考工题解", 辽宁人民出版社, pages: 95 - 96 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020192090A1 (en) * | 2019-03-27 | 2020-10-01 | 苏州长光华医生物医学工程有限公司 | Kit storage rack preventing magnetic particle deposition |
| CN113088430A (en) * | 2021-04-09 | 2021-07-09 | 广州新成生物科技有限公司 | Rotary magnetic attraction device |
| CN116419699A (en) * | 2021-11-10 | 2023-07-11 | 飞利浦家电控股有限公司 | Kitchen appliance |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109336950A (en) | A kind of magnetic frame | |
| ES2366653T3 (en) | DEVICE AND PROCEDURE FOR THE SEPARATION OF MAGNETIC OR MAGNETIZABLE PARTICLES OF A LIQUID. | |
| JP6030197B2 (en) | Device and method for manipulating and mixing magnetic particles in a liquid medium | |
| ES2335080T3 (en) | METHOD FOR IMPROVING UNION INTERACTIONS BETWEEN UNION COUPLE MEMBERS. | |
| EP1467817B1 (en) | Apparatus for retaining magnetic particles within a flow-through cell | |
| US8585279B2 (en) | Device and method for manipulating and mixing magnetic particles in a liquid medium | |
| US8870446B2 (en) | Device and method for manipulating and mixing magnetic particles in a liquid medium | |
| US8993342B2 (en) | Magnetic separation unit, magnetic separation device and method for separating magnetic substance in bio-samples | |
| CN209226887U (en) | A kind of magnetic frame | |
| CN105185504A (en) | Flow sorting device for cell beads | |
| CN101203757A (en) | Apparatus for moving magnetic particles | |
| CN206004166U (en) | A kind of transmission cabinet adopting 11 folded sections | |
| CN204807380U (en) | Clinical laboratory is with automatic device that thoughtlessly shakes of blood | |
| CN207596873U (en) | A kind of tilting magnetic force rack device | |
| CN215655765U (en) | Centrifugal equipment is used in inspection of clinical laboratory of hospital | |
| CN208839494U (en) | Agitating device | |
| CN204946637U (en) | Cell magnetic bead airflow classification device | |
| CN207619380U (en) | A kind of comprehensive nucleic acid extraction magnetic frame | |
| CN212403585U (en) | Compound excitation wave magnetizer | |
| CN218290866U (en) | Magnetic force frame | |
| CN207554472U (en) | A kind of chassis locking device for security device | |
| CN205868068U (en) | Triaxial lift dyestuff mixer | |
| CN205868069U (en) | Biax lift dyestuff mixer | |
| CN205797482U (en) | A kind of mineral magnetic separator | |
| CN211111956U (en) | Magnetic rack for efficiently adsorbing magnetic beads |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |