CN207619380U - A kind of comprehensive nucleic acid extraction magnetic frame - Google Patents
A kind of comprehensive nucleic acid extraction magnetic frame Download PDFInfo
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- CN207619380U CN207619380U CN201721636417.2U CN201721636417U CN207619380U CN 207619380 U CN207619380 U CN 207619380U CN 201721636417 U CN201721636417 U CN 201721636417U CN 207619380 U CN207619380 U CN 207619380U
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- pedestal
- upper cover
- magnetic frame
- nucleic acid
- acid extraction
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Abstract
The utility model discloses a kind of comprehensive nucleic acid extraction magnetic frames, including the pedestal mutually fastened and upper cover, pedestal includes base board and the pedestal step at base board both ends is arranged, and upper cover includes upper cover plate and the upper cover step at upper cover plate both ends is arranged, and pedestal step is connected with upper cover step;It is provided with two rows of the first mounting holes being mutually parallel on upper cover plate, there are two the second mounting holes for setting on the pedestal step of pedestal side.The magnetic frame of the utility model can be used for fixing the EP pipes of different size specification, to increase the practical ranges of magnetic frame by the way that two kinds of mounting holes are arranged on the pedestal step of upper cover plate and pedestal side respectively;The stability that EP pipes are placed on magnetic frame can be effectively ensured, provided a convenient to experimental implementation;Its is simple in structure, easy to operate, easy to carry, highly practical, has a extensive future.
Description
Technical field
The utility model is related to molecular biology apparatus fields, more particularly, to a kind of comprehensive nucleic acid extraction magnetic force
Frame.
Background technology
With the development of biotechnology, nucleic acid extraction and construction of gene library technology based on paramagnetic particle method more adapt to produce
The requirement of object high-purity, sample high throughput.Magnetic frame designs and application has a significant impact to experimental result.The type of magnetic frame is numerous
More, purposes is various.Divide according to purposes, there is nucleic acid extraction magnetic frame and gene library magnetic frame etc.;Divide according to specification, has
PCR EP pipes magnetic frame, 1.5ml EP pipes magnetic frame, 2ml EP pipes magnetic frames and 15ml EP pipe magnetic frames etc..The material of magnetic frame
Expect varied, there is shaped plastics, magnetic material type etc..The structure of magnetic frame is also not quite similar.
The principal element for influencing the application effect of magnetic frame has:Material forms and physical arrangement;The material of magnetic frame forms
Stability not only determine service life of magnetic frame, but also influence experimental result, physical arrangement determines the purposes of magnetic frame, to reality
Simplicity, the sample throughput etc. for testing operation have a very big impact.
However, existing magnetic frame exist mostly of single specification, inefficiency and it is complicated the defects of, practical application by
To considerable restraint.In conclusion on the basis of existing magnetic frame structure design achievement, the knot present in existing magnetic frame is overcome
Structure defect, design and develop a kind of high efficiency, high throughput, multipurpose, it is economical and practical and be easy to portable magnetic frame have it is important
Practical significance.
Invention content
In view of the deficienciess of the prior art, the utility model provides a kind of comprehensive nucleic acid extraction magnetic frame.
The utility model adopts the following technical solution:
A kind of comprehensive nucleic acid extraction magnetic frame, including the pedestal and upper cover that mutually fasten, the pedestal includes base board
With the pedestal step at base board both ends is set, the upper cover includes upper cover plate and the upper cover step at upper cover plate both ends is arranged,
The pedestal step is connected with the upper cover step;Two rows of the first installations being mutually parallel are provided on the upper cover plate
Hole, there are two the second mounting holes for setting on the pedestal step of the pedestal wherein side.
In the above-mentioned technical solutions, length direction of the pedestal step for being provided with the second mounting hole along the base board
Thickness be 1.5-2.5cm, be equipped with elastic fastener on the inside of the hole of second mounting hole.
Preferably, in the above-mentioned technical solutions, the pedestal step, which is equipped with, fastens protrusion, and the upper cover step is equipped with
The compatible buckled recess with fastening protrusion;Or the upper cover step is equipped with and fastens protrusion, is set on the pedestal step
There is the compatible buckled recess with fastening protrusion.
Preferably, in the above-mentioned technical solutions, the base board is equipped with two rows of first positioning holes being mutually parallel, each institute
First positioning hole is stated to correspond with each first mounting hole;On the inside of the pedestal step of the pedestal other side there are two settings
Second location hole, each second location hole are corresponded with each second mounting hole.
It is further preferred that in the above-mentioned technical solutions, the madial wall of the pedestal step is equipped with for clamping magnet
Card slot.
Still further preferably, in the above-mentioned technical solutions, the base board is equipped with rectangle positive stop strip, described rectangular
The setting of shape positive stop strip is between two rows of first positioning holes.
It is further preferred that in the above-mentioned technical solutions, the width of the width and the card slot of the rectangle positive stop strip
Spend equal, the height of the rectangle positive stop strip is 2.5-4mm.
Preferably, in the above-mentioned technical solutions, first mounting hole and the first positioning hole respectively with 1.5ml EP
The outer edge and bottom mating of pipe;Second mounting hole and the second location hole respectively with the outer edge of 15ml EP pipes and
Bottom mating.
In the above-mentioned technical solutions, the cross section for fastening protrusion is rectangle, circle or semicircle.
In the above-mentioned technical solutions, the base board is an integral molding structure with the pedestal step, the upper cover plate with
The upper cover step is an integral molding structure.
The utility model has the advantages that:
(1) comprehensive nucleic acid extraction magnetic frame provided by the utility model passes through respectively in upper cover plate and pedestal side
Two kinds of mounting holes are set on pedestal step, can be used for fixing the EP pipes of different size specification, to increase the reality of magnetic frame
Application range, in addition by controlling the depth for the second mounting hole being arranged on pedestal step and adding elastic fastener, effectively
The fixed effect of the second mounting hole is enhanced, practical application effect is good;
(2) comprehensive nucleic acid extraction magnetic frame provided by the utility model by the first mounting hole and first positioning hole,
The stability that EP pipes are placed on magnetic frame can be effectively ensured in the cooperation of second mounting hole and second location hole, give experimental implementation
It provides a convenient;
(3) comprehensive nucleic acid extraction magnetic frame provided by the utility model between two rows of first positioning holes by being arranged
Rectangle positive stop strip improves conventional efficient, and provide to experimental implementation to which the separation of magnetic bead and solution be effectively ensured
It is convenient;
(4) by fastening protrusion between the pedestal and upper cover of comprehensive nucleic acid extraction magnetic frame provided by the utility model
Fastening installation is carried out with buckled recess, it is simple in structure, it is easy to operate, it is easy to carry, it is operated, can be subtracted convenient for passing through the volley of rifle fire
Few operating process substantially increases the flux of nucleic acid purification, and shorten nucleic acid purification because of error caused by multiple liquid relief
Time, it is highly practical, have a extensive future.
Description of the drawings
Fig. 1 is a kind of structural representation of the comprehensive nucleic acid extraction magnetic frame provided according to the utility model embodiment 1
Figure;
Fig. 2 for a kind of pedestal of the comprehensive nucleic acid extraction magnetic frame provided according to the utility model embodiment 1 knot
Structure schematic diagram;
Fig. 3 for a kind of upper cover of the comprehensive nucleic acid extraction magnetic frame provided according to the utility model embodiment 1 knot
Structure schematic diagram;
In figure:
Pedestal 1 (base board 11, first positioning hole 111, rectangle positive stop strip 112, pedestal step 12, the second mounting hole
121, elastic fastener 1211 fastens protrusion 122, second location hole 123, card slot 124), upper cover 2 (upper cover plate 21, the first installation
Hole 211, upper cover step 22, buckled recess 221).
Specific implementation mode
With reference to specific embodiment, specific embodiment of the present utility model is described in further detail.Following reality
It applies example and is merely to illustrate the utility model, be not intended to limit the specific protection domain of the utility model.
In the description of the present invention, unless otherwise indicated, the meaning of " plurality " is two or more;Term
The orientation of the instructions such as "upper", "lower", "left", "right", "inner", "outside", " front end ", " rear end ", " head ", " tail portion " or position are closed
System is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of describing this practicality newly plough and simplified description, rather than
Indicate or imply that signified device or element must have a particular orientation, with specific azimuth configuration and operation, therefore cannot
It is construed as a limitation of the present invention.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can
It, can also be indirectly connected through an intermediary to be to be connected directly.It for the ordinary skill in the art, can be specific
Situation understands the concrete meaning of above-mentioned term in the present invention.
Embodiment 1
As shown in Figs. 1-3, a kind of comprehensive nucleic acid extraction magnetic frame that the utility model embodiment is provided, including it is mutual
The pedestal 1 and upper cover 2 of fastening, wherein:The pedestal 1 includes base board 11, and the both ends of the base board 11 are equipped with pedestal step
12, the upper cover 2 includes upper cover plate 21, and the both ends of the upper cover plate 21 are equipped with upper cover step 22;It is set on the pedestal step 12
There are fastening protrusion 122, the upper cover step 22 to be equipped with compatible buckled recess 221, the pedestal 1 with fastening protrusion
It is connected as one by fastening protrusion 122 and the cooperation of buckled recess 221 with upper cover 2.
Two rows of the first mounting holes 211 being mutually parallel are provided on the upper cover plate 21, what the two rows were mutually parallel
First mounting hole 211 is arranged along the length direction of the upper cover plate 21 to be extended;Meanwhile two rows of phases are equipped on the base board 11
Mutually parallel first positioning hole 111, length direction of the first positioning hole 111 that the two rows are mutually parallel along the base board 11
Arrangement extends, and each first positioning hole 111 is corresponded with each first mounting hole 211.
There are two the second mounting holes 121 for setting on the pedestal step 12 of 1 side of the pedestal, described to be provided with the second peace
The pedestal step 12 in dress hole 121 is 2.0cm along the thickness of the length direction of the base board 11, the hole of second installation 121
Inside is pasted with elastic fastener 1211 made of rubber material;Meanwhile in the pedestal step 12 of 1 other side of the pedestal
There are two second location hole 123, each second location holes 123 to be corresponded with each second mounting hole 121 for side setting.
Specifically, the surface structure of first mounting hole 211 and 1.5ml EP pipes matches, the first positioning hole
111 match with the bottom structures of 1.5ml EP pipes;The surface structure of second mounting hole 121 and 15ml EP pipes matches,
The bottom structure of the second location hole 123 and 15ml EP pipes matches.
The card slot 124 for clamping magnet is equipped on the madial wall of the pedestal step 12;On the base board 11
Equipped with rectangle positive stop strip 112, the rectangle positive stop strip 112 is arranged between two rows of first positioning holes 111, and described
The width of rectangle positive stop strip 112 is equal with the width of the card slot 124, and the height of the rectangle positive stop strip 112 is 3mm.
The base board 11 is an integral molding structure with the pedestal step 12, the upper cover plate 21 and the tegmen table
Rank 22 is also an integral molding structure.
In use, being first mounted on magnet in the card slot 124 of the pedestal 1, upper cover 2 is then mounted on the pedestal 1
On, when installation, it is recessed that the fastening protrusion 122 on the pedestal step 12 is fastened to the fastening being mounted on the upper cover step 22
In slot 221, you can realize that pedestal 1 and the fastening of upper cover 2 are installed, then 1.5ml EP pipes are sequentially arranged at the first mounting hole 211
In, and the bottom of 1.5ml EP pipes is positioned by first positioning hole 111, has ensured the installation site of 1.5ml EP pipes, so
Afterwards, 15ml EP pipes are sequentially arranged in the second mounting hole 121, and the bottom of 15ml EP pipes by second location hole 123 into
Row positioning, has ensured the installation site of 15ml EP pipes.
Embodiment 2
A kind of comprehensive nucleic acid extraction magnetic frame that the utility model embodiment is provided, it is basic with the structure of embodiment 1
Pedestal and upper cover identical, including mutually fasten, wherein:The pedestal includes base board, and the both ends of the base board are equipped with bottom
Seat stand rank, the upper cover include upper cover plate, and the both ends of the upper cover plate are equipped with upper cover step.
With embodiment 1 difference lies in:The pedestal step is equipped with buckled recess, and the upper cover step, which is equipped with, to be fastened
Protrusion;In addition,
The first positioning hole on the first mounting hole and the base board on the upper cover plate is outer with 2ml EP pipes respectively
Edge and bottom mating;The second mounting hole and second location hole on the pedestal step respectively with the outer edge of PCR EP pipes and
Bottom mating.
In the above-described embodiments, the cross section for fastening protrusion could be provided as rectangle, circle or semicircle, certainly
It can be set as other shapes according to actual demand.
In summary, the comprehensive nucleic acid extraction magnetic frame that the utility model embodiment is provided passes through respectively in upper cover plate
With two kinds of mounting holes of setting on the pedestal step of pedestal side, it can be used for fixing the EP pipes of different size specification, to increase
The practical ranges of magnetic frame;By the cooperation of the first mounting hole and first positioning hole, the second mounting hole and second location hole,
The stability that EP pipes are placed on magnetic frame can be effectively ensured, provided a convenient to experimental implementation;By ranked first positioning two
Rectangle positive stop strip is set between hole, to which the separation of magnetic bead and solution be effectively ensured, improves conventional efficient, and to experiment
Operation is provided convenience;It carries out fastening installation by the fastening protrusion between pedestal and upper cover with buckled recess, simple in structure,
It is easy to operate, it is easy to carry, it is operated convenient for passing through the volley of rifle fire, operating process can be reduced because caused by multiple liquid relief accidentally
Difference, substantially increases the flux of nucleic acid purification, and shortens the time of nucleic acid purification, highly practical, has a extensive future.
Finally, the preferred embodiment that these are only the utility model is not intended to limit the protection model of the utility model
It encloses.Within the spirit and principle of the utility model, any modification, equivalent replacement, improvement and so on should be included in this
Within the protection domain of utility model.
Claims (10)
1. a kind of comprehensive nucleic acid extraction magnetic frame, which is characterized in that including the pedestal mutually fastened and upper cover, the pedestal packet
It includes base board and the pedestal step at base board both ends is set, the upper cover includes upper cover plate and is arranged in the upper of upper cover plate both ends
Lid step, the pedestal step are connected with the upper cover step;Two rows of the to be mutually parallel are provided on the upper cover plate
One mounting hole, there are two the second mounting holes for setting on the pedestal step of the pedestal wherein side.
2. comprehensive nucleic acid extraction magnetic frame according to claim 1, which is characterized in that described to be provided with the second mounting hole
Pedestal step along the thickness of the length direction of the base board be 1.5-2.5cm, be equipped on the inside of the hole of second mounting hole
Elastic fastener.
3. comprehensive nucleic acid extraction magnetic frame according to claim 2, which is characterized in that the pedestal step is equipped with button
Protrusion is closed, the upper cover step is equipped with the compatible buckled recess with fastening protrusion;Or the upper cover step is equipped with
Protrusion is fastened, the pedestal step is equipped with the compatible buckled recess with fastening protrusion.
4. comprehensive nucleic acid extraction magnetic frame according to claim 2, which is characterized in that the base board is equipped with two rows
The first positioning hole being mutually parallel, each first positioning hole are corresponded with each first mounting hole;The pedestal is another
There are two second location hole, each second location hole is a pair of with each second mounting hole one for setting on the inside of the pedestal step of side
It answers.
5. comprehensive nucleic acid extraction magnetic frame according to claim 4, which is characterized in that the madial wall of the pedestal step
It is equipped with the card slot for clamping magnet.
6. comprehensive nucleic acid extraction magnetic frame according to claim 5, which is characterized in that the base board is equipped with rectangular
Shape positive stop strip, the rectangle positive stop strip setting is between two rows of first positioning holes.
7. comprehensive nucleic acid extraction magnetic frame according to claim 6, which is characterized in that the width of the rectangle positive stop strip
Degree is equal with the width of the card slot, and the height of the rectangle positive stop strip is 2.5-4mm.
8. comprehensive nucleic acid extraction magnetic frame according to claim 4, which is characterized in that first mounting hole and described
The first positioning hole outer edge and bottom mating with 1.5ml EP pipes respectively;Second mounting hole and the second location hole point
Not with the outer edge and bottom mating of 15ml EP pipes.
9. comprehensive nucleic acid extraction magnetic frame according to claim 3, which is characterized in that the cross section for fastening protrusion
For rectangle, circle or semicircle.
10. according to the comprehensive nucleic acid extraction magnetic frame of claim 1-9 any one of them, which is characterized in that the base board
It is an integral molding structure with the pedestal step, the upper cover plate is an integral molding structure with the upper cover step.
Priority Applications (1)
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CN201721636417.2U CN207619380U (en) | 2017-11-29 | 2017-11-29 | A kind of comprehensive nucleic acid extraction magnetic frame |
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CN201721636417.2U CN207619380U (en) | 2017-11-29 | 2017-11-29 | A kind of comprehensive nucleic acid extraction magnetic frame |
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CN207619380U true CN207619380U (en) | 2018-07-17 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114366171A (en) * | 2021-12-23 | 2022-04-19 | 滁州学院 | Full-automatic sampler and method for detecting nucleic acid of new coronavirus |
-
2017
- 2017-11-29 CN CN201721636417.2U patent/CN207619380U/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114366171A (en) * | 2021-12-23 | 2022-04-19 | 滁州学院 | Full-automatic sampler and method for detecting nucleic acid of new coronavirus |
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