CN109331170A - A kind of qi-blood tonifying crocodile donkey-hide gelatin composition - Google Patents
A kind of qi-blood tonifying crocodile donkey-hide gelatin composition Download PDFInfo
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- CN109331170A CN109331170A CN201811473787.8A CN201811473787A CN109331170A CN 109331170 A CN109331170 A CN 109331170A CN 201811473787 A CN201811473787 A CN 201811473787A CN 109331170 A CN109331170 A CN 109331170A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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Abstract
The invention discloses a kind of qi-blood tonifying crocodile donkey-hide gelatin compositions, including following parts by weight of component: 5-40 parts of crocodile polypeptides and 4-10 parts of donkey-hide gelatin liquid.The present invention passes through the crocodile polypeptide for being added to prepare using modern biotechnology zymolysis technique in formula, more conducively absorption of human body amino acid and polypeptide, can more effectively retain the active constituent of crocodile, improve the bioavilability of composition to greatest extent and its effect that fills blood.
Description
Technical field
The present invention relates to a kind of qi-blood tonifying crocodile donkey-hide gelatin compositions.
Background technique
QI belonging to YANG, blood pertaining to YIN, airway dysfunction to push, it is warm based on, blood function with nutrition, moisten based on.It is deposited between qi and blood
In the relationship of qi being the governor of blood, blood being the material foundation of QI.Qi being the governor of blood refers to that qi promoting blood production, the promoting circulation of blood of gas energy and gas can unite blood etc. two
Broad aspect.Qi promoting blood production: the metaplasia process of blood be unable to do without gasification.Either ingesta is converted to essence of water and grain, essence of water and grain turns
Chemical conversion ying-qi and body fluid, ying-qi and body fluid are converted to the process of blood, or essence is converted to the process of blood, requires by gas
Effect.Arrogant, then green blood is sufficient.The deficiency of vital energy then influences the metaplasia of blood, the deficiency of blood even occurs.So tonifying Qi will enrich blood simultaneously, support
Life must know gas and blood relationship.
Summary of the invention
The present invention is intended to provide a kind of qi-blood tonifying crocodile donkey-hide gelatin composition.
To achieve the goals above, present invention provide the technical scheme that a kind of qi-blood tonifying crocodile donkey-hide gelatin composition,
Including following parts by weight of component: 5-40 parts of crocodile polypeptides and 4-10 parts of donkey-hide gelatin liquid.
As a preferred solution of the present invention, the qi-blood tonifying crocodile donkey-hide gelatin composition includes following parts by weight of component:
10-30 parts of crocodile polypeptides and 6-9 parts of donkey-hide gelatin liquid.
Wherein, the crocodile polypeptide is prepared by following step: after crocodile meat is cleaned removal adipose tissue, being cut into broken
Block is set after boiling water bath boils, and homogenate, after trypsin digestion is added, being placed in boiling water bath inactivates enzyme, is cooled to room temperature, and is filtered,
It is dry to get.
The solid-liquid ratio of the crocodile fragment and boiling water is 1:1.2-2.2.
The time that the boiling water bath boils is 25-35min.
The dosage of the trypsase is the 0.6-0.8%, enzymolysis time 2-3h of crocodile meat quality.
Wherein, the donkey-hide gelatin liquid is prepared by following step: add water to be put into pulverizer in blocky donkey-hide gelatin and crushes, 86-89
After DEG C heating water bath and stirring and dissolving, centrifugation removal oil reservoir.
The ratio of the bulk donkey-hide gelatin and water is 1:16-18, centrifugal rotational speed 9000r/min, is centrifuged 6-8min.
As a preferred solution of the present invention, the qi-blood tonifying crocodile donkey-hide gelatin composition further includes following parts by weight group
Point: 10-25 parts of Radix Astragalis, 5-8 parts of Rhizoma Atractylodis Macrocephalaes, 10-25 parts of Radix Codonopsis, 7-13 portions of fructus lyciis, 9-13 parts of Rehmannia glutinosas, 10-17 portions of Chinese yams and
2-12 portions of Radix Glycyrrhizaes.
As a preferred solution of the present invention, the qi-blood tonifying crocodile donkey-hide gelatin composition further includes following parts by weight group
Point: 13-18 parts of Radix Astragalis, 5-7 parts of Rhizoma Atractylodis Macrocephalaes, 17-23 parts of Radix Codonopsis, 10-12 portions of fructus lyciis, 10-12 parts of Rehmannia glutinosas, 11-14 portions of Chinese yams
With 4-9 portions of Radix Glycyrrhizaes.
The beneficial effects of the present invention are:
Composition provided by the present invention is added to more using the crocodile of modern biotechnology zymolysis technique preparation in formula
Peptide, more conducively absorption of human body amino acid and polypeptide can more effectively retain active constituent in crocodile, improve combination to greatest extent
The bioavilability of object and its effect that fills blood.
In addition, donkey-hide gelatin is as women tonic, donkey-hide gelatin is mainly based on bulk in the market, and inconvenient to use, mouthfeel is bad, and
Nutrition is more single.In view of the foregoing drawbacks, water bath with thermostatic control is dissolved into donkey-hide gelatin liquid after the present invention crushes donkey-hide gelatin.
The present invention is also equipped with Radix Astragali, Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, fructus lycii, Rehmannia glutinosa, Chinese yam and Radix Glycyrrhizae, enhances the bowl spares of composition
QI invigorating, the effect of nourishing yin and supplementing blood.
Specific embodiment
Claim of the invention is described in further detail With reference to embodiment, but is not constituted to this
Any restrictions of invention, any limited times modification made within the claims in the present invention protection scope, still of the invention
Within claims.
Embodiment 1
A kind of qi-blood tonifying crocodile donkey-hide gelatin composition, including following parts by weight of component: 23 parts of crocodile polypeptides and 7 parts of donkey-hide gelatin
Liquid.
Embodiment 2
A kind of qi-blood tonifying crocodile donkey-hide gelatin composition, including following parts by weight of component: 10 parts of crocodile polypeptides and 9 parts of donkey-hide gelatin
Liquid, 13 parts of Radix Astragalis, 7 parts of Rhizoma Atractylodis Macrocephalaes, 17 parts of Radix Codonopsis, 12 portions of fructus lyciis, 10 parts of Rehmannia glutinosas, 14 portions of Chinese yams and 4 portions of Radix Glycyrrhizaes.
Embodiment 3
A kind of qi-blood tonifying crocodile donkey-hide gelatin composition, including following parts by weight of component: 30 parts of crocodile polypeptides and 6 parts of donkey-hide gelatin
Liquid, 18 parts of Radix Astragalis, 5 parts of Rhizoma Atractylodis Macrocephalaes, 23 parts of Radix Codonopsis, 10 portions of fructus lyciis, 12 parts of Rehmannia glutinosas, 11 portions of Chinese yams and 9 portions of Radix Glycyrrhizaes.
Embodiment 4
A kind of qi-blood tonifying crocodile donkey-hide gelatin composition, including following parts by weight of component: 20 parts of crocodile polypeptides and 7 parts of donkey-hide gelatin
Liquid, 16 parts of Radix Astragalis, 6 parts of Rhizoma Atractylodis Macrocephalaes, 21 parts of Radix Codonopsis, 11 portions of fructus lyciis, 11 parts of Rehmannia glutinosas, 13 portions of Chinese yams and 6 portions of Radix Glycyrrhizaes.
Crocodile polypeptide in embodiment 1-4 is prepared by following step: after crocodile meat is cleaned removal adipose tissue, being cut into
Fragment is added in boiling water by solid-liquid ratio 1:1.2-2.2, and 25-35min is boiled in bath, is homogenized, and is added crocodile meat quality 0.6-0.8%'s
Trypsase digests 2-3h, and being placed in boiling water bath inactivates enzyme, is cooled to room temperature, and filters, it is dry to get.
Donkey-hide gelatin liquid in embodiment 1-4 is prepared by following step: blocky donkey-hide gelatin is added to water by solid-liquid ratio 1:16-18
In, it crushes, after 86-89 DEG C of heating water bath and stirring and dissolving, 6-8min is centrifuged under 9000r/min, removes oil reservoir.
Composition in embodiment 1-4 is prepared by following step: after mixing by each component, sterilizing, packaging.
Clinical research of the present invention carries out clinical verification to 100 syndrome of deficiency of both qi and blood and deficient qi and blood card dysmenorrhea patient.As a result
Prove: 1-4 of the embodiment of the present invention, which prepares resulting composition, has the effect of blood-enrich, for syndrome of deficiency of both qi and blood and asthenia of qi and blood
The having a dizzy spell of weak card, the diseases such as deficiency of QI with disinclination to talk, shortness of breath, spontaneous perspiration, palpitation and insomnia, lustreless complexion have obviously improvement result,
Peripheral blood HB, RBC increases significant after treatment；Treating syndrome of deficiency of both qi and blood and deficient qi and blood card dysmenorrhea total effective rate is respectively 94.7%
With 98.9%, obvious adverse reaction and toxic side effect are had no.
Claims (10)
1. a kind of qi-blood tonifying crocodile donkey-hide gelatin composition, which is characterized in that including following parts by weight of component: 5-40 portions of crocodiles are more
Peptide and 4-10 parts of donkey-hide gelatin liquid.
2. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 1, which is characterized in that including following parts by weight group
Point: 10-30 parts of crocodile polypeptides and 6-9 parts of donkey-hide gelatin liquid.
3. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 1 or claim 2, which is characterized in that the crocodile polypeptide is logical
It crosses following step preparation: after crocodile meat is cleaned removal adipose tissue, being cut into fragment, set after boiling water bath boils, pancreas egg is added in homogenate
After white enzyme enzymatic hydrolysis, being placed in boiling water bath inactivates enzyme, is cooled to room temperature, and filters, it is dry to get.
4. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 3, which is characterized in that the crocodile fragment and boiling water
Solid-liquid ratio be 1:1.2-2.2.
5. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 3, which is characterized in that the time that the boiling water bath boils
For 25-35min.
6. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 3, which is characterized in that the dosage of the trypsase
For the 0.6-0.8% of crocodile meat quality, enzymolysis time 2-3h.
7. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 1 or claim 2, which is characterized in that the donkey-hide gelatin liquid passes through
Following step preparation: adding water to be put into pulverizer in blocky donkey-hide gelatin and crush, after 86-89 DEG C of heating water bath and stirring and dissolving, centrifugation
Remove oil reservoir.
8. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 7, which is characterized in that the bulk donkey-hide gelatin and water
Ratio is 1:16-18, centrifugal rotational speed 9000r/min, is centrifuged 6-8min.
9. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 1, which is characterized in that further include following parts by weight group
Point: 10-25 parts of Radix Astragalis, 5-8 parts of Rhizoma Atractylodis Macrocephalaes, 10-25 parts of Radix Codonopsis, 7-13 portions of fructus lyciis, 9-13 parts of Rehmannia glutinosas, 10-17 portions of Chinese yams and
2-12 portions of Radix Glycyrrhizaes.
10. qi-blood tonifying crocodile donkey-hide gelatin composition according to claim 9, which is characterized in that further include following parts by weight
Component: 13-18 parts of Radix Astragalis, 5-7 parts of Rhizoma Atractylodis Macrocephalaes, 17-23 parts of Radix Codonopsis, 10-12 portions of fructus lyciis, 10-12 parts of Rehmannia glutinosas, 11-14 parts of mountains
Medicine and 4-9 portions of Radix Glycyrrhizaes.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811473787.8A CN109331170A (en) | 2018-12-04 | 2018-12-04 | A kind of qi-blood tonifying crocodile donkey-hide gelatin composition |
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| CN201811473787.8A CN109331170A (en) | 2018-12-04 | 2018-12-04 | A kind of qi-blood tonifying crocodile donkey-hide gelatin composition |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101878849A (en) * | 2010-06-13 | 2010-11-10 | 厦门大学 | Polypeptide powder of crocodile and preparation method and application thereof |
| CN105963422A (en) * | 2016-07-07 | 2016-09-28 | 广东伊茗药业有限公司 | Blood-enriching medicine oral liquid containing donkey-hide gelatin |
| CN106075057A (en) * | 2016-07-05 | 2016-11-09 | 缪建林 | A kind of formula for qi and blood tonifying |
| CN106310209A (en) * | 2016-11-11 | 2017-01-11 | 东莞市百替生物科技有限公司 | Chinese herb preparation for treating qi-blood deficiency and preparation method |
-
2018
- 2018-12-04 CN CN201811473787.8A patent/CN109331170A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101878849A (en) * | 2010-06-13 | 2010-11-10 | 厦门大学 | Polypeptide powder of crocodile and preparation method and application thereof |
| CN106075057A (en) * | 2016-07-05 | 2016-11-09 | 缪建林 | A kind of formula for qi and blood tonifying |
| CN105963422A (en) * | 2016-07-07 | 2016-09-28 | 广东伊茗药业有限公司 | Blood-enriching medicine oral liquid containing donkey-hide gelatin |
| CN106310209A (en) * | 2016-11-11 | 2017-01-11 | 东莞市百替生物科技有限公司 | Chinese herb preparation for treating qi-blood deficiency and preparation method |
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Application publication date: 20190215 |