CN109331155B - Traditional Chinese medicine composition for preventing and treating simple renal cyst - Google Patents
Traditional Chinese medicine composition for preventing and treating simple renal cyst Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for preventing and treating simple renal cyst, which comprises the following components in parts by weight: 10-15 parts of eucommia ulmoides, 10-15 parts of dipsacus root, 10-15 parts of parasitic loranthus, 10-15 parts of achyranthes bidentata, 20-30 parts of plantain seed, 20-30 parts of poria cocos, 15-20 parts of corn stigma, 10-15 parts of cowherb seed, 15-20 parts of chingma abutilon seed, 5-10 parts of spina gleditsiae, 5-10 parts of curcuma zedoary, 5-10 parts of roasted turtle shell and 15-20 parts of red peony root. Also discloses application of the traditional Chinese medicine composition in preparing a medicine for preventing and treating simple renal cyst and reducing postoperative recurrence rate of the simple renal cyst. The traditional Chinese medicine composition is a pure traditional Chinese medicine composition, has wide medicine sources, low cost, small toxic and side effects, good curative effect and short treatment course, particularly has obvious curative effect on reducing the recurrence rate of simple renal cyst treatment, and is suitable for clinical popularization and application.
Description
Technical Field
The invention belongs to the traditional Chinese medicine technology, and particularly relates to a traditional Chinese medicine composition for preventing and treating simple renal cyst.
Background
Simple Renal Cysts (SRCs) in the kidney of adults are common benign lesions, the incidence rate is generally less than 5%, and the pathogenesis of SRCs is not completely clear. The incidence of the disease increases with age, and is mainly considered to be due to aging of the body with loss of nephrons, and compensatory increase of the body with workload of the remaining nephrons, resulting in hypertrophy or hyperplasia of renal tubular cells, and finally cyst formation.
At present, the clinical treatment mainly adopts surgical open operation, B-ultrasonic or CT guided puncture drainage sclerotherapy, laparoscopic technology and other methods. Open surgery is rarely adopted at present due to the defects of large trauma, more pain, high cost, high complication incidence rate, slow recovery and the like; the sclerosing agent injected by percutaneous puncture has good effect on the small cysts, and for the cysts with large volume, the sclerosing agent is not easy to absorb, and the focus is easy to relapse; the laparoscope has the advantages of small wound, quick recovery, high curative effect and the like, and is one of the first-choice methods for renal cyst surgical treatment at present, but the laparoscope has the defects of expensive equipment, difficult technology control, need of performing general anesthesia and the like, and can generate complications such as retroperitoneal hematoma, damage to peripheral organs, hypercapnia, intestinal obstruction, internal hernia and the like, and a considerable number of patients change to open surgery for various reasons in the laparoscope. The B-ultrasonic guided percutaneous aspiration sclerotomy is accepted and implemented by hospitals and patients due to the advantages of small trauma, quick recovery, low cost, high safety and the like, but the high recurrence rate is still the main defect of the B-ultrasonic guided percutaneous aspiration sclerotomy compared with the surgical operation.
Disclosure of Invention
The purpose of the invention is as follows: in view of the above problems in the prior art, the present application provides a Chinese medicinal composition for preventing and treating simple renal cyst.
The technical scheme is as follows: the application provides a traditional Chinese medicine composition for preventing and treating simple renal cyst, which comprises the following components in parts by weight: 10-15 parts of eucommia ulmoides, 10-15 parts of dipsacus root, 10-15 parts of parasitic loranthus, 10-15 parts of achyranthes bidentata, 20-30 parts of plantain seed, 20-30 parts of poria cocos, 15-20 parts of corn stigma, 10-15 parts of cowherb seed, 15-20 parts of chingma abutilon seed, 5-10 parts of spina gleditsiae, 5-10 parts of curcuma zedoary, 5-10 parts of roasted turtle shell and 15-20 parts of red peony root.
The traditional Chinese medicine composition for preventing and treating simple renal cysts according to claim 1, which comprises the following components in parts by weight: 10 parts of eucommia ulmoides, 10 parts of dipsacus root, 15 parts of parasitic loranthus, 10 parts of radix achyranthis bidentatae, 20 parts of semen plantaginis, 20 parts of poria cocos, 15 parts of corn stigma, 10 parts of cowherb seed, 20 parts of cluster mallow seed, 10 parts of spina gleditsiae, 10 parts of rhizoma zedoariae, 10 parts of roasted turtle shell and 15 parts of red paeony root.
The decoction of the traditional Chinese medicine composition is carried out in a conventional manner, and specifically comprises the following steps: the herbs were soaked in tap water for 30 minutes. And (3) decocting at a high temperature, wherein the water adding amount of the first decoction is 3-5 cm higher than the medicine surface, the water adding amount of the second decoction is 2-3 cm higher than the medicine surface, the first decoction is preferably carried out for 20-30 minutes, and the second decoction is preferably carried out for 15-20 minutes. Mixing the two decoctions, and collecting 400ml of the decoction for warm administration twice in the morning and evening. The traditional Chinese medicine composition can also be prepared into powder, tablets, pills, capsules, granules and the like.
The traditional Chinese medicine composition disclosed by the invention has the main effects that the traditional Chinese medicine raw materials comprise:
eucommia ulmoides: tonify liver and kidney, strengthen tendons and bones. It can be used for treating soreness of waist and back, weakness of feet and knees, hypertension, renal interstitial fibrosis, and osteoporosis. And (3) radix dipsaci: strengthen tendons and bones, benefit liver and kidney, stop bleeding. Treating soreness of waist and back; limb atrophy and paralysis; traumatic injury, muscle and bone injury, metrorrhagia, spermatorrhea, leukorrhagia, superficial infection, sore and swelling. Parasitic loranthus: nourish liver and kidney, strengthen tendons and bones, dispel wind-damp. It is indicated for wind-damp arthralgia, soreness and weakness of waist and knees, weakness of tendons and bones, and hypertension. Achyranthes bidentata: tonify liver and kidney, strengthen tendons and bones, induce diuresis to treat stranguria, activate blood and remove stasis. Treating soreness of waist and knees; flaccidity of the lower limbs; mass; the cell coat is not dropped; hot spraying; blood stranguria; traumatic injury; carbuncle and swelling and malignant sore; swollen and sore throat. Tuckahoe, poria cocos: induce diuresis and drain dampness, invigorate spleen and calm heart. It is indicated for edema, proteinuria, hypertension, loose stool, diarrhea, palpitation, and insomnia. Plantain seed: clearing away heat, promoting urination, eliminating dampness, treating stranguria, improving eyesight, and eliminating phlegm. It is indicated for edema, heat stranguria, pain with astringents, hypertension, hyperuricemia, conjunctival congestion, swelling and pain, phlegm heat cough. Corn silk: induce diuresis to alleviate edema, clear liver heat and promote bile flow. It can be used for treating edema, dribbling urine, jaundice, cholecystitis, cholelithiasis, hypertension, diabetes, and galactostasis. Mallow seeds: induce diuresis to smooth intestine, clear heat and expel pus. It is indicated for stranguria, galactostasis and constipation. Red peony root: clear heat and cool blood, activate blood and dispel stasis. It is indicated for abdominal mass, abdominal pain, traumatic injury, abscess, sore and ulcer. Zedoary turmeric: move qi, break blood, resolve food stagnation and alleviate pain. It is indicated for distending pain of heart and abdomen, mass, accumulation and indigestion. Spina gleditsiae: promoting blood circulation, dispelling pathogenic wind, relieving swelling, and expelling pus. For abscess, swelling, sores, pestilential wind, ringworm sores and retained fetal membranes. Turtle shell: soften hardness and dissipate nodulation, nourish yin and clear heat, calm liver and stop wind. It is indicated for mass, wind-dampness in the abdomen, amenorrhea and amenorrhea due to yin deficiency. Seed of cowherb: relieve swelling, heal wound, promote blood circulation, dredge meridians, induce lactation. It is indicated for amenorrhea, galactostasis, dystocia, stranguria with blood, carbuncle, swelling and bleeding due to incised wound.
In the treatment of simple renal cyst, no matter what kind of factors cause, the general pathogenesis is kidney deficiency as the basis, and dampness and blood stasis are combined, and the general treatment method of warming kidney, promoting diuresis and removing blood stasis is used. The traditional Chinese medicine composition takes the thick eucommia bark, the dipsacus root, the mistletoe and the radix achyranthis bidentatae to tonify the kidney, strengthen the waist, tonify the kidney and replenish qi to ensure that the kidney is not deficient, thereby relieving a plurality of symptoms such as waist soreness, lumbago, knee weakness and the like, blocking the root cause of diseases and achieving the purpose of treating diseases and seeking the root cause. For patients with edema of lower limbs, dry mouth, bitter taste, abdominal distension, even little ascites, red tongue with white or yellow greasy coating, slippery and rapid or soft-superficial and rapid pulse, B-ultrasonic wave showing large cyst and more cyst fluid, and serious damp evil, the composition of the invention selects four drugs of poria cocos, plantain seed, corn stigma and cluster mallow which are light in flavor and induce diuresis to alleviate damp evil and slow the decline without hurting the deficient body. The tuckahoe, with mild nature and sweet and light taste, enters kidney, spleen and heart channels, has the effects of promoting water and eliminating dampness, has the function of invigorating spleen, and can strengthen the body resistance and eliminate pathogenic factors simultaneously so as to eliminate pathogenic factors without damaging the body resistance. The simple renal cyst is not easy to discover in the early stage, the disease is often discovered only when clinical symptoms appear, the cyst is accompanied by more than years, the traditional Chinese medicine considers that the long-term disease is regarded as blood stasis, the traditional Chinese medicine has special effect on the tangible pathogenic factors of the simple renal cyst, such as products for promoting blood circulation, removing blood stasis and softening hard masses, the formula uses red paeony root, zedoary, turtle shell, cowherb seed and spina gleditsiae for promoting blood circulation, removing blood stasis and softening hard masses, the layers are well-defined, wherein the cowherb seed is bitter and flat, can promote the circulation of meridians, smoothen blood and promote urination, has the effects of promoting blood circulation and promoting urination, can promote diuresis and remove dampness and blood stasis, and has the dual-purpose effect of one medicine. The Chinese medicinal composition is taken 13 medicines in total, and the medicines for tonifying the kidney, promoting diuresis and removing blood stasis are used together, so that the pathogenesis of the renal cyst is determined.
The dosage and the method of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is in dosage of one day, one dose of decoction is taken orally every day, and the decoction is taken twice. A course of treatment is 28 days, and 1-2 courses of treatment are generally taken. During the period of using the Chinese medicinal composition of the invention, the patients should pay attention to: fasting coffee, chocolate, strong tea, polluted deteriorated products, little food such as high salt, spicy stimulation and the like; it is contraindicated for patients with hemorrhage.
The traditional Chinese medicine composition can be used for preventing the occurrence and development of simple renal cyst; if the cyst size is larger than 4cm, the simple renal cyst recurrence rate can be reduced by the recommended combination with western medicine operation treatment.
Has the advantages that: the traditional Chinese medicine composition is a pure traditional Chinese medicine composition, has wide medicine sources, low cost, small toxic and side effects, good curative effect and short treatment course, achieves the purposes of preventing and treating the simple renal cyst and reducing the postoperative recurrence rate by tonifying the kidney, promoting diuresis and removing blood stasis, particularly has obvious curative effect on reducing the treatment recurrence rate of the simple renal cyst, and is suitable for clinical popularization and application.
Detailed Description
The following provides a detailed description of embodiments of the invention.
Example 1
The traditional Chinese medicine composition for treating the simple renal cyst comprises the following components in parts by weight:
10g of thick eucommia bark, 10g of dipsacus root, 15g of Chinese taxillus twig, 10g of radix achyranthis bidentatae, 20g of semen plantaginis, 20g of poria cocos, 15g of corn stigma, 10g of cowherb seed, 20g of cluster mallow seed, 10g of spina gleditsiae, 10g of rhizoma zedoariae, 10g of roasted turtle shell and 15g of red paeony root.
Example 2
The traditional Chinese medicine composition for treating the simple renal cyst comprises the following components in parts by weight:
15g of thick eucommia bark, 15g of dipsacus root, 15g of Chinese taxillus twig, 15g of radix achyranthis bidentatae, 30g of semen plantaginis, 20g of poria cocos, 15g of corn stigma, 15g of cowherb seed, 15g of cluster mallow seed, 5g of spina gleditsiae, 5g of rhizoma zedoariae, 5g of roasted turtle shell and 15g of red paeony root.
Example 3
The traditional Chinese medicine composition for treating the simple renal cyst comprises the following components in parts by weight:
10g of thick eucommia bark, 10g of dipsacus root, 10g of Chinese taxillus twig, 10g of radix achyranthis bidentatae, 20g of semen plantaginis, 30g of poria cocos, 20g of corn stigma, 10g of cowherb seed, 20g of cluster mallow seed, 10g of spina gleditsiae, 10g of rhizoma zedoariae, 10g of roasted turtle shell and 20g of red peony root.
Example 4
The traditional Chinese medicine composition for treating the simple renal cyst comprises the following components in parts by weight:
13g of thick eucommia bark, 13g of dipsacus root, 13g of Chinese taxillus twig, 13g of radix achyranthis bidentatae, 25g of semen plantaginis, 25g of poria cocos, 18g of corn stigma, 10g of cowherb seed, 18g of cluster mallow seed, 8g of spina gleditsiae, 8g of curcuma zedoary, 8g of roasted turtle shell and 18g of red paeony root.
The decocting mode of the traditional Chinese medicine composition in the embodiment 1-4 is as follows: weighing each herbal medicine according to the formula amount, and soaking the herbal medicines in tap water for 30 minutes; and then decocting at high temperature, wherein the water adding amount of the first decoction is 3 cm higher than the medicine surface, the water adding amount of the second decoction is 3 cm higher than the medicine surface, the first decoction is preferably carried out for 20-30 minutes, and the second decoction is preferably carried out for 15-20 minutes. Mixing the two decoctions, and collecting 400ml of the decoction for warm administration twice in the morning and evening.
Clinical curative effect
The traditional Chinese medicine liquid prepared by the four embodiments is applied to clinic for clinical comparison research, and 54 patients with renal cyst are divided into a control group (B-ultrasonic guided puncture liquid drawing sclerosis) and a treatment group (puncture combined kidney tonifying, dampness removing and blood stasis removing traditional Chinese medicine decoction oral treatment for 28 days). The B-ultrasonic of the puncture cyst is rechecked 3, 6 and 12 months after the row puncture liquid drawing sclerosis operation, and the statistical result is shown in the following table:
cyst size comparison in each time period before and after treatment in two groups ([ M (P25-P75) ])
Note: *: p is less than 0.05 after treatment compared to before treatment of the same group; and (delta): the P of the treated group is less than 0.05 compared with the P of the control group at the same time
And (4) conclusion: the volume of the cyst in the treatment group is obviously smaller than the volume before puncture (P is less than 0.05) in three times of reexamination; the volume of the rechecked cyst is also significantly different from the volume before puncture after 3, 6 and 12 months in the control group (P < 0.05); after 12 months of treatment, the cyst volume of the treated group is obviously different from that of the control group (P is less than 0.05). Among them, the traditional Chinese medicine composition 1 of example 1 has the most significant effect.
The Chinese medicinal composition can also be directly taken by patients with cyst less than 4cm for treatment.
Clinical examples: the patient is old, the left kidney has a cyst with the size of 3.2cm by physical examination, and the composition shown in the preferred formula example 1 of the traditional Chinese medicine is directly applied by considering that the cyst size does not reach the surgical indication, wherein the specific medicines are as follows: 10g of thick eucommia bark, 10g of dipsacus root, 15g of Chinese taxillus twig, 10g of radix achyranthis bidentatae, 20g of semen plantaginis, 20g of poria cocos, 15g of corn stigma, 10g of cowherb seed, 20g of cluster mallow seed, 10g of spina gleditsiae, 10g of rhizoma zedoariae, 10g of roasted turtle shell and 15g of red paeony root. The preparation is decocted for 3 months for administration with cyst of 3.0cm, and the patient is ordered to continue taking the preparation, and periodically re-examined, and the cyst size of the left side of the patient is maintained at about 3.0cm all the time in the last year, so as to obtain better control.
Claims (3)
1. A traditional Chinese medicine composition for reducing the postoperative recurrence rate of simple renal cyst is characterized by comprising the following components in parts by weight: 10-15 parts of eucommia ulmoides, 10-15 parts of dipsacus root, 10-15 parts of parasitic loranthus, 10-15 parts of achyranthes bidentata, 20-30 parts of plantain seed, 20-30 parts of poria cocos, 15-20 parts of corn stigma, 10-15 parts of cowherb seed, 15-20 parts of chingma abutilon seed, 5-10 parts of spina gleditsiae, 5-10 parts of curcuma zedoary, 5-10 parts of roasted turtle shell and 15-20 parts of red peony root.
2. The traditional Chinese medicine composition for reducing the postoperative recurrence rate of simple renal cyst according to claim 1, which is characterized by comprising the following components in parts by weight: 10 parts of eucommia ulmoides, 10 parts of dipsacus root, 15 parts of parasitic loranthus, 10 parts of radix achyranthis bidentatae, 20 parts of semen plantaginis, 20 parts of poria cocos, 15 parts of corn stigma, 10 parts of cowherb seed, 20 parts of cluster mallow seed, 10 parts of spina gleditsiae, 10 parts of rhizoma zedoariae, 10 parts of roasted turtle shell and 15 parts of red paeony root.
3. Use of the composition of claim 1 or 2 for the preparation of a medicament for reducing the rate of recurrence after simple renal cyst surgery.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104491735A (en) * | 2014-12-26 | 2015-04-08 | 青岛市中心医院 | Traditional Chinese medicine formula for treating kidney tumor |
| CN104623415A (en) * | 2015-02-07 | 2015-05-20 | 陈红 | Pharmaceutical composition for treating nephropathy and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491735A (en) * | 2014-12-26 | 2015-04-08 | 青岛市中心医院 | Traditional Chinese medicine formula for treating kidney tumor |
| CN104623415A (en) * | 2015-02-07 | 2015-05-20 | 陈红 | Pharmaceutical composition for treating nephropathy and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 补肾通瘀消积方治疗肾囊肿52例疗效观察;王悟云;《河北中医》;20001231(第10期);751-752 * |
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