CN109331141A - 一种用于治疗心肌梗塞的中药组合物 - Google Patents
一种用于治疗心肌梗塞的中药组合物 Download PDFInfo
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Abstract
本发明提出一种用于治疗心肌梗塞的中药组合物，用于治疗心肌梗塞的中药组合物的配方中包括丹参、没药、延胡索、五灵脂、高良姜、丁香、小茴香、枳壳、香附、白檀香、半夏、瓜蒌皮、桔梗、甘草、砂仁、薏苡仁。本发明所述的用于治疗心肌梗塞的中药组合物具有配方合理、无毒副作用、治疗成本低、治疗心机梗塞时的疗效迅速的优点。
Description
技术领域
本发明涉及中药领域，具体涉及一种用于治疗心肌梗塞的中药组合物。
背景技术
冠心病中医论证属于胸痹、真心痛范畴，心血管内的血瘀、血栓、心脉不通为其主要病机，临床伴有并发症的共同特点，其特点属于人体气血亏虚，标实为兼夹气滞、痰浊及血瘀等。心肌梗塞是冠心病中的一种，心肌梗塞与人饮食、喝酒、吸烟有关，高蛋白、高脂肪、高油脂是人体中的血凝、血栓的前身，心梗的患者一般都存在正气亏虚、气滞、寒凝、心脉不畅、心血管堵塞、心肌供血不足等问题，造成心梗的病理因素包括环境气候、心理压力、体力疲劳、睡眠不足、阳气阴气上下不协调等。
心肌梗塞的治疗方法有多种，其中包括药物治疗、冠状动脉介入治疗、搭桥手术治疗等治疗方式，尽管治疗方式取得了较大的进步，但仍存在的问题包括：1、临床症状未缓解，时常会出现气短、疲倦、乏力等症状；2、冠脉血管仍有不同程度狭窄，或支架内的血瘀、血栓再造狭窄；3、部分患者生活质量及远期生存率并没有得到很大的改善。同时通过这些方式进行治疗时治疗费用昂贵，一般患者无法承受。
发明内容
本发明的目的提供一种用于治疗心肌梗塞的中药组合物，解决上述现有技术问题中的一个或多个。
本发明提出一种用于治疗心肌梗塞的中药组合物，用于治疗心肌梗塞的中药组合物的配方中包括丹参、没药、延胡索、五灵脂、高良姜、丁香、小茴香、枳壳、香附、白檀香、半夏、瓜蒌皮、桔梗、甘草、砂仁、薏苡仁。
其中，所述丹参含丹参酮，为强壮性通经剂，有祛瘀、生新、活血的功效；没药具有活血化瘀的功效；延胡索能够活血行气，使得气与血并；五灵脂性味甘温，入肝经，具有疏通血脉、散瘀止痛的功效；高良姜具有散寒止痛的功效，能够归脾、胃经；丁香能够起到温中降逆、行气止痛的功效；小茴香具有理气散寒、增强肠胃蠕动、促进积存气体的排出的功效；枳壳具有理气宽中、行滞消胀的功效；香附有理气解郁的功效；白檀香性味归经，具有理气宽胸、散寒止痛的功效；半夏具有燥湿化痰、降逆止咳的功效；瓜蒌皮具有清肺化痰、力气宽胸散结的功效；桔梗具有止咳祛痰、去除痰浊、宣肺、排脓的功效；甘草具有清热解毒、祛痰止咳、调和众药的功效；砂仁具有温脾开胃、化湿行气的功效；薏苡仁具有利水消肿、健脾祛湿、舒筋除痹、清热排脓的功效。
其中，所述用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参25-35份、没药10-20份、延胡索10-20份、五灵脂10-20份、高良姜140-150份、丁香10-20份、小茴香10-20份、枳壳25-35份、香附10-20份、白檀香10-20份、半夏25-35份、瓜蒌皮25-35份；桔梗25-35份；甘草40-50份；砂仁10-20份；薏苡仁10-20份。
进一步，所述用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参27-33份、没药12-18份、延胡索12-18份、五灵脂12-18份、高良姜142-148份、丁香12-18份、小茴香12-18份、枳壳27-33份、香附12-18份、白檀香12-18份、半夏27-33份、瓜蒌皮27-33份；桔梗27-33份；甘草42-48份；砂仁12-18份；薏苡仁12-18份。
更进一步，所述用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参30份、没药15份、延胡索15份、五灵脂15份、高良姜145份、丁香15份、小茴香15份、枳壳30份、香附15份、白檀香15份、半夏30份、瓜蒌皮30份；桔梗30份；甘草45份；砂仁15份；薏苡仁15份。
一种用于治疗心肌梗塞的中药组合物的煎制方法，包括如下步骤：
步骤1、按照用于治疗心肌梗塞的中药组合物的配方中的各个组分的重量份数称取对应份数的组分，形成用于治疗心肌梗塞的中药组合物；
步骤2、将用于治疗心肌梗塞的中药组合物加入到药壶中，然后加入水，浸泡20-30分钟，形成一次混合物；
步骤3、浸泡完成后利用武火将一次混合物烧开，然后转至文火煎制1.5小时，滤出药液，药壶中剩余药渣，向药壶中添加水，浸泡5-10分钟，形成二次混合物；
步骤4、浸泡完成后利用武火将二次混合物烧开，然后转至文火煎制1.5小时，滤出药液，药壶中剩余药渣，向药壶中添加水，形成三次混合物；
步骤5、利用武火将三次混合物烧开，然后转至文火煎制1.5小时，滤出药液，将药壶中剩余的药渣倒出，并将药壶清洗干净；
步骤6、将步骤3、步骤4和步骤5中得到的三份药液依次倒入药壶中形成混合液，然后利用武火将混合液烧开，然后转至文火煎制浓缩，直至浓缩后的液体的体积是混合液的体积的0.2-0.4倍，停止煎制，得到用于治疗心肌梗塞的浓缩药液。
其中，所述步骤2中的水的体积是用于治疗心肌梗塞的中药组合物的体积的1.5-2.5倍。
其中，所述所述步骤3中的水的体积是药渣的体积的1.3-1.8倍。
其中，所述所述步骤4中的水的体积是药渣的体积的1.2-1.5倍。
本发明所述的一种用于治疗心肌梗塞的中药组合物的优点为：配方合理，无毒副作用，在治疗心机梗塞方面疗效迅速，使用本发明中所述的用于治疗心肌梗塞的中药组合物后可以停止服用抗血瘀的药，不需要再安装支架，有效的降低了患者的医疗成本。
附图说明
图1为患者服用按照本发明的实施例5中的配方制取的用于治疗心肌梗塞的浓缩药液前的心电图；
图2为患者服用按照本发明的实施例5中的配方制取的用于治疗心肌梗塞的浓缩药液后的心电图。
具体实施方式
实施例1
一种用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参25份、没药10份、延胡索10份、五灵脂10份、高良姜140份、丁香10份、小茴香10份、枳壳25份、香附10份、白檀香10份、半夏25份、瓜蒌皮25份；桔梗25份；甘草40份；砂仁10份；薏苡仁10份。
实施例2
一种用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参35份、没药20份、延胡索20份、五灵脂20份、高良姜150份、丁香20份、小茴香20份、枳壳35份、香附20份、白檀香20份、半夏35份、瓜蒌皮35份；桔梗35份；甘草50份；砂仁20份；薏苡仁20份。
实施例3
一种用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参27份、没药12份、延胡索12份、五灵脂12份、高良姜142份、丁香12份、小茴香12份、枳壳27份、香附12份、白檀香12份、半夏27份、瓜蒌皮27份；桔梗27份；甘草42份；砂仁12份；薏苡仁12份。
实施例4
一种用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参33份、没药18份、延胡索18份、五灵脂18份、高良姜148份、丁香18份、小茴香18份、枳壳33份、香附18份、白檀香18份、半夏33份、瓜蒌皮33份；桔梗33份；甘草48份；砂仁18份；薏苡仁18份。
实施例5
一种用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参30份、没药15份、延胡索15份、五灵脂15份、高良姜145份、丁香15份、小茴香15份、枳壳30份、香附15份、白檀香15份、半夏30份、瓜蒌皮30份；桔梗30份；甘草45份；砂仁15份；薏苡仁15份。
按照实施例1至实施例5中所述的用于治疗心肌梗塞的中药组合物的配方按照下述的用于治疗心肌梗塞的中药组合物的煎制方法进行用于治疗心肌梗塞的浓缩药液的煎制。
一种用于治疗心肌梗塞的中药组合物的煎制方法，包括如下步骤：
步骤1、以克为单位按照用于治疗心肌梗塞的中药组合物的配方中的各个组分的重量份数称取对应份数的组分，其中1份等于1克，形成用于治疗心肌梗塞的中药组合物；
步骤2、将用于治疗心肌梗塞的中药组合物加入到药壶中，然后加入水，浸泡20-30分钟，形成一次混合物，其中水的体积是用于治疗心肌梗塞的中药组合物的体积的1.5-2.5倍；
步骤3、浸泡完成后利用武火将一次混合物烧开，然后转至文火煎制1.5小时，滤出药液，药壶中剩余药渣，向药壶中添加水，浸泡5-10分钟，形成二次混合物，其中水的体积是药渣的体积的1.3-1.8倍；
步骤4、浸泡完成后利用武火将二次混合物烧开，然后转至文火煎制1.5小时，滤出药液，药壶中剩余药渣，向药壶中添加水，形成三次混合物，其中水的体积是药渣的体积的1.2-1.5倍；
步骤5、利用武火将三次混合物烧开，然后转至文火煎制1.5小时，滤出药液，将药壶中剩余的药渣倒出，并将药壶清洗干净；
步骤6、将步骤3、步骤4和步骤5中得到的三份药液依次倒入药壶中形成混合液，然后利用武火将混合液烧开，然后转至文火煎制浓缩，直至浓缩后的液体的体积是混合液的体积的0.2-0.4倍，停止煎制，得到用于治疗心肌梗塞的浓缩药液。
按照实施例1至实施例5中所述的用于治疗心肌梗塞的中药组合物的配方煎制的用于治疗心肌梗塞的浓缩药液均为两天的药剂量，需要平均分配到两天进行服用。其中实施例1和实施例3适用于有性功能减退、高血压以及浮肿病症的患者，实施例1和实施例3对于气温比较高的地方的患者使用，实施例2和实施例4对于气温比较低的地方的患者比较使用。
赵某某，江苏人，60岁，如图1所示2012年11月6日所做的心电图显示赵某某在服用按照实施例5制取的用于治疗心肌梗塞的浓缩药液前，赵某某患急性广泛前壁心肌梗塞，如图2所示2012年12月31日所做的心电图显示赵某某为亚急性前壁心肌梗死，心肌梗死与心肌梗塞没有本质上的区别，病情得到了有效的控制，在2012年11月6日至2012年12月31日之间赵某某未住院治疗，同时也未使用其他如阿司匹林、氯吡格雷、替格瑞洛、西洛他唑等抗血瘀药物，只将按照实施例5制取的用于治疗心肌梗塞的浓缩药液的一天的药剂量均分到早、晚进行服用，在2012年12月31日至今，赵某某未复发。用于治疗心肌梗塞的中药组合物治疗心机梗塞时疗效迅速，用于治疗心肌梗塞的中药组合物虽然不能改变心肌梗塞对心脏带来的损害，不排除免除陈旧心梗迹象，但对患者的远期生存及生活质量不产生影响。
以上所述仅是本发明的优选方式，应当指出，对于本领域普通技术人员来说，在不脱离本发明创造构思的前提下，还可以做出若干相似的变形和改进，这些也应视为本发明的保护范围之内。
Claims (8)
1.一种用于治疗心肌梗塞的中药组合物，其特征在于，用于治疗心肌梗塞的中药组合物的配方中包括丹参、没药、延胡索、五灵脂、高良姜、丁香、小茴香、枳壳、香附、白檀香、半夏、瓜蒌皮、桔梗、甘草、砂仁、薏苡仁。
2.根据权利要求1所述的一种用于治疗心肌梗塞的中药组合物，其特征在于，所述用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参25-35份、没药10-20份、延胡索10-20份、五灵脂10-20份、高良姜140-150份、丁香10-20份、小茴香10-20份、枳壳25-35份、香附10-20份、白檀香10-20份、半夏25-35份、瓜蒌皮25-35份；桔梗25-35份；甘草40-50份；砂仁10-20份；薏苡仁10-20份。
3.根据权利要求2所述的一种用于治疗心肌梗塞的中药组合物，其特征在于，所述用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参27-33份、没药12-18份、延胡索12-18份、五灵脂12-18份、高良姜142-148份、丁香12-18份、小茴香12-18份、枳壳27-33份、香附12-18份、白檀香12-18份、半夏27-33份、瓜蒌皮27-33份；桔梗27-33份；甘草42-48份；砂仁12-18份；薏苡仁12-18份。
4.根据权利要求3所述的一种用于治疗心肌梗塞的中药组合物，其特征在于，所述用于治疗心肌梗塞的中药组合物的配方中各个组分的重量份数为：丹参30份、没药15份、延胡索15份、五灵脂15份、高良姜145份、丁香15份、小茴香15份、枳壳30份、香附15份、白檀香15份、半夏30份、瓜蒌皮30份；桔梗30份；甘草45份；砂仁15份；薏苡仁15份。
5.权利要求2至4中任意一项中所述的一种用于治疗心肌梗塞的中药组合物的煎制方法，其特征在于，包括如下步骤：
步骤1、按照用于治疗心肌梗塞的中药组合物的配方中的各个组分的重量份数称取对应份数的组分，形成用于治疗心肌梗塞的中药组合物；
步骤2、将用于治疗心肌梗塞的中药组合物加入到药壶中，然后加入水，浸泡20-30分钟，形成一次混合物；
步骤3、浸泡完成后利用武火将一次混合物烧开，然后转至文火煎制1.5小时，滤出药液，药壶中剩余药渣，向药壶中添加水，浸泡5-10分钟，形成二次混合物；
步骤4、浸泡完成后利用武火将二次混合物烧开，然后转至文火煎制1.5小时，滤出药液，药壶中剩余药渣，向药壶中添加水，形成三次混合物；
步骤5、利用武火将三次混合物烧开，然后转至文火煎制1.5小时，滤出药液，将药壶中剩余的药渣倒出，并将药壶清洗干净；
步骤6、将步骤3、步骤4和步骤5中得到的三份药液依次倒入药壶中形成混合液，然后利用武火将混合液烧开，然后转至文火煎制浓缩，直至浓缩后的液体的体积是混合液的体积的0.2-0.4倍，停止煎制，得到用于治疗心肌梗塞的浓缩药液。
6.根据权利要求5所述的一种用于治疗心肌梗塞的中药组合物的煎制方法，其特征在于，所述步骤2中的水的体积是用于治疗心肌梗塞的中药组合物的体积的1.5-2.5倍。
7.根据权利要求5所述的一种用于治疗心肌梗塞的中药组合物的煎制方法，其特征在于，所述所述步骤3中的水的体积是药渣的体积的1.3-1.8倍。
8.根据权利要求5所述的一种用于治疗心肌梗塞的中药组合物的煎制方法，其特征在于，所述所述步骤4中的水的体积是药渣的体积的1.2-1.5倍。
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| 易为丹等: "急性心肌梗死心血瘀阻证古代文献研究", 《辽宁中医药大学学报》 * |
| 沈炎南: "验案四则", 《广西中医药》 * |
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