CN109331134A - 一种治疗犬猫耳螨病的中药及其制备方法 - Google Patents

一种治疗犬猫耳螨病的中药及其制备方法 Download PDF

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CN109331134A
CN109331134A CN201811550786.9A CN201811550786A CN109331134A CN 109331134 A CN109331134 A CN 109331134A CN 201811550786 A CN201811550786 A CN 201811550786A CN 109331134 A CN109331134 A CN 109331134A
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陈琳
邹金峰
滕钟秀
马朝庆
滕晓弘
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Dandong Ruifeng Animal Pharmaceutical Co Ltd
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Abstract

本发明涉及动物疾病治疗的中药领域，具体为一种治疗犬猫耳螨病的中药及其制备方法。一种治疗犬猫耳螨病的中药，由以下重量份数的原料制成：槟榔8‑15份、石榴皮10‑20份、百部10‑20份、狼毒10‑25份、地肤子8‑15份、苦参10‑20份、黄柏8‑15份、蛇床子15‑25份、花椒10‑20份、黄芪15‑30份、艾叶10‑20份、败酱15‑30份、冰片3‑8份。将上述中药投入中药提取罐中，加水煎煮、回流提取两次，合并两次煎液后过滤，滤液浓缩后冷却至室温，然后加入无水乙醇进行醇沉，过滤后得到上清液即为中药液。本发明的中药可有效治疗犬猫耳螨病症状，缓解瘙痒、外耳部炎症和局部过敏反应等症状。

Description

一种治疗犬猫耳螨病的中药及其制备方法
技术领域
本发明涉及动物疾病治疗的中药领域，具体为一种治疗犬猫耳螨病的中药及其制备方法。
背景技术
随着社会经济发展及人们生活品质的提升，我国宠物行业得到了飞速发展，宠物健康也日益受到宠物主人和宠物医师的重视。
犬、猫的耳痒螨是由于犬耳痒螨寄生于犬外耳道引起的外耳部炎症，靠刺破皮肤吸吮淋巴液及食表皮鳞屑为主，因对局部的剧烈刺激，使局部皮肤增厚，产生红褐色的痂皮，导致犬发生外耳炎。有高度的传染性，有瘙痒感。
犬、猫常自己抓伤，使皮肤渗出、增厚和形成结痂。接触耳螨的皮肤会有严重的瘙痒和局部过敏反应。一般集中在耳道，头部和颈部，严重的情况可能全身瘙痒。耳朵的瘙痒表现为用后腿挠耳朵或甩头。常见犬猫摇头，有时甚至出现耳血肿或水肿而使整个耳部肿大，发炎或过敏反应。犬的耳道呈“L”形，因其特殊的结构很容易积聚油脂、灰尘和水分，特别是贵宾犬，一方面耳朵附近的长毛容易将耳道遮盖，使耳道空气不通畅。另一方面其耳道内生长着很多的耳毛，容易积污垢潮湿而使耳道感染发炎。严重的情况会造成中耳炎或内耳炎，可能有听力受损，失去平衡等症状。
目前治疗主要用各种洗液或者消毒液冲洗外耳道，同时注射伊维菌素来治疗。这种方法治疗周期比较长，最少需要3个周的治疗，而且容易反复发作，产生耐药。
发明内容
本发明的目的是提供一种治疗犬猫耳螨病的中药及其制备方法。
为实现上述目的，本发明采用技术方案为：
一种治疗犬猫耳螨病的中药，由以下重量份数的原料制成：槟榔8-15份、石榴皮10-20份、百部10-20份、狼毒10-25份、地肤子8-15份、苦参10-20份、黄柏8-15份、蛇床子15-25份、花椒10-20份、黄芪15-30份、艾叶10-20份、败酱15-30份、冰片3-8份。
优选的，由以下重量份数的原料制成：槟榔10份、石榴皮15份、百部15份、狼毒15份、地肤子10份、苦参15份、黄柏10份、蛇床子20份、花椒15份、黄芪20份、艾叶15份、败酱20份、冰片5份。
所述的治疗犬猫耳螨病的中药的制备方法，将上述中药投入中药提取罐中，加水煎煮、回流提取两次，合并两次煎液后过滤，滤液浓缩后冷却至室温，然后加入无水乙醇进行醇沉，过滤后得到上清液即为中药液。
所述回流提取两次的具体步骤为，第一次煮沸后回流提取2小时，第二次煮沸后回流提取1小时，煮沸条件为常压下100℃，第一次加水量为总药材质量的10倍，第二次加水量为总药材质量的8倍。
所述滤液浓缩过程中温度为60-70℃，真空度为-0.06MPa，浓缩液相对密度为1.10-1.20。
加入无水乙醇使体系中乙醇的终浓度为65％，静置24小时，过滤得到上清液。
本发明的回流提取的制备方法可以使中药的有效成分充分释放，增强药物疗效。
不同的药物互相配伍，其中有效成分不相同，有效成分间相互作用也不相同，应该从整体上考量中药组合物的治疗效果，同时，各药物的用量不同，药物用量的不同会对整体药效有很大的影响,中药的药味加减、药量增减都会对其功用产生不同影响，会改变其君、臣的配伍关系，从而改变作用部位和药物性能，导致其功用与主治则迥然有别。本发明的各种中药组分科学配伍使用，具有杀虫、清热、止痒，祛湿、排脓的功效。
本发明中药由槟榔、石榴皮、百部、狼毒、地肤子、苦参、黄柏、蛇床子、花椒、黄芪、艾叶、败酱、冰片组成。耳螨病治疗以杀虫、清热、止痒、固表为原则。槟榔、百部、狼毒、苦参配伍使用具有杀虫、杀菌的功效，地肤子、黄柏、蛇床子、花椒、败酱配伍使用可清热、祛湿、排脓、止痒，黄芪、石榴皮配伍使用可收敛固表，另配冰片，可以增加各药物的透皮性，使药物快速渗透皮下发挥作用。
本发明的有益效果：
本发明的中药可有效治疗犬猫耳螨病症状，缓解瘙痒、外耳部炎症和局部过敏反应等症状。
本发明的中药具有杀虫止痒的功效，治疗周期短，治疗彻底，不易复发，具有很好的市场前景。
本发明为纯中药制剂，不会产生耐药性，可以反复使用。
具体实施方式
实施例1
槟榔10份、石榴皮15份、百部15份、狼毒15份、地肤子10份、苦参15份、黄柏10份、蛇床子20份、花椒15份、黄芪20份、艾叶15份、败酱20份、冰片5份，将上述中药投入中药提取罐中，加水煎煮、回流提取两次，合并两次煎液后过滤，滤液浓缩后冷却至室温，然后加入无水乙醇使体系中乙醇的终浓度为65％，静置24小时，过滤得到上清液即为中药液。回流提取两次的具体步骤为，第一次煮沸后回流提取2小时，第二次煮沸后回流提取1小时，煮沸条件为常压下100℃，第一次加水量为总药材质量的10倍，第二次加水量为总药材质量的8倍。滤液浓缩过程中温度为70℃，真空度为-0.06MPa，浓缩液相对密度为1.15。
实施例2
槟榔8份、石榴皮10份、百部10份、狼毒10份、地肤子8份、苦参10份、黄柏8份、蛇床子15份、花椒10份、黄芪15份、艾叶10份、败酱15份、冰片3份，将上述中药按顺序投入中药提取罐中，加水煎煮、回流提取两次，合并两次煎液后过滤，滤液浓缩后冷却至室温，然后加入无水乙醇使体系中乙醇的终浓度为65％，静置24小时，过滤得到上清液即为中药液。回流提取两次的具体步骤为，第一次煮沸后回流提取2小时，第二次煮沸后回流提取1小时，煮沸条件为常压下100℃，第一次加水量为总药材质量的10倍，第二次加水量为总药材质量的8倍。滤液浓缩过程中温度为60℃，真空度为-0.06MPa，浓缩液相对密度为1.10。
实施例3
槟榔15份、石榴皮20份、百部20份、狼毒25份、地肤子15份、苦参20份、黄柏15份、蛇床子25份、花椒20份、黄芪30份、艾叶20份、败酱30份、冰片8份，将上述中药按顺序投入中药提取罐中，加水煎煮、回流提取两次，合并两次煎液后过滤，滤液浓缩后冷却至室温，然后加入无水乙醇使体系中乙醇的终浓度为65％，静置24小时，过滤得到上清液即为中药液。回流提取两次的具体步骤为，第一次煮沸后回流提取2小时，第二次煮沸后回流提取1小时，煮沸条件为常压下100℃，第一次加水量为总药材质量的10倍，第二次加水量为总药材质量的8倍。滤液浓缩过程中温度为70℃，真空度为-0.06MPa，浓缩液相对密度为1.20。
临床试验
具体用法用量：喷涂患处，每天3次，连续用药7-15天。
选取30只症状病猫病犬，受试药物为实施例1制备的中药，具体的用法用量为喷涂患处，每天3次，连续用药15天，治愈率可达到90％以上。20天后复查，没有复发情况。

Claims (6)

1.一种治疗犬猫耳螨病的中药，其特征在于，由以下重量份数的原料制成：槟榔8-15份、石榴皮10-20份、百部10-20份、狼毒10-25份、地肤子8-15份、苦参10-20份、黄柏8-15份、蛇床子15-25份、花椒10-20份、黄芪15-30份、艾叶10-20份、败酱15-30份、冰片3-8份。
2.按权利要求1所述的治疗犬猫耳螨病的中药，其特征在于，由以下重量份数的原料制成：槟榔10份、石榴皮15份、百部15份、狼毒15份、地肤子10份、苦参15份、黄柏10份、蛇床子20份、花椒15份、黄芪20份、艾叶15份、败酱20份、冰片5份。
3.一种权利要求1或2所述的治疗犬猫耳螨病的中药的制备方法，其特征在于：将上述中药投入中药提取罐中，加水煎煮、回流提取两次，合并两次煎液后过滤，滤液浓缩后冷却至室温，然后加入无水乙醇进行醇沉，过滤后得到上清液即为中药液。
4.按权利要求3所述的治疗犬猫耳螨病的中药的制备方法，其特征在于：所述回流提取两次的具体步骤为，第一次煮沸后回流提取2小时，第二次煮沸后回流提取1小时，煮沸条件为常压下100℃，第一次加水量为总药材质量的10倍，第二次加水量为总药材质量的8倍。
5.根据权利要求3所述的治疗犬猫耳螨病的中药，其特征在于，所述滤液浓缩过程中温度为60-70℃，真空度为-0.06MPa，浓缩液相对密度为1.10-1.20。
6.根据权利要求3所述的治疗犬猫耳螨病的中药，其特征在于，加入无水乙醇使终浓度为65％，静置24小时，过滤得到上清液。
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111821381A (zh) * 2020-08-25 2020-10-27 东晟源研究院(广州)有限公司 一种含中药组合物的猫耳护理水及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107669956A (zh) * 2017-11-08 2018-02-09 河南牧业经济学院 治疗犬、猫耳病的中药制剂及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107669956A (zh) * 2017-11-08 2018-02-09 河南牧业经济学院 治疗犬、猫耳病的中药制剂及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
范玉娟等: "犬皮肤病的诊断与治疗 ", 《新疆畜牧业》 *
谢馨梅等: "犬螨虫病的治疗 ", 《畜牧兽医科技信息》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111821381A (zh) * 2020-08-25 2020-10-27 东晟源研究院(广州)有限公司 一种含中药组合物的猫耳护理水及其制备方法
CN111821381B (zh) * 2020-08-25 2021-09-21 东晟源研究院(广州)有限公司 一种含中药组合物的猫耳护理水及其制备方法

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