CN109329727A - Antioxidant composition, anti-oxidation preparation and application - Google Patents
Antioxidant composition, anti-oxidation preparation and application Download PDFInfo
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- CN109329727A CN109329727A CN201811258222.8A CN201811258222A CN109329727A CN 109329727 A CN109329727 A CN 109329727A CN 201811258222 A CN201811258222 A CN 201811258222A CN 109329727 A CN109329727 A CN 109329727A
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Classifications
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The present invention provides a kind of antioxidant compositions, it include: the quinoa of 2~50 parts by weight, the acerola concentrate of 0.1~5 parts by weight, the Bilberry fruit P.E of 0.1~3 parts by weight, the grape seed extract of 0.01~3 parts by weight, the broccoli seed water extract of 0.01~0.3 parts by weight and the roselle of 0.1~3 parts by weight.Present invention also provides a kind of anti-oxidation preparations and preparation method thereof.Present invention also provides antioxidant compositions or anti-oxidation preparation to prepare the application in antioxidant food, drug or health food.Antioxidant composition provided by the present application has good antioxidation, and each natural constituents are synergistic, safe and non-toxic, applied widely, has the function of anti-oxidant, anti-aging well to human body.
Description
Technical field
The present invention relates to technical field of health care food more particularly to a kind of antioxidant compositions, anti-oxidation preparation and application.
Background technique
With the development of modern biology and medical research, a large number of studies show that oxidation caused by excessive free radical in vivo
It stress be a key factor of generation, the development and human senility of a variety of diseases of the mankind.Free radical is that the molecule of compound exists
Under the external conditions such as photo-thermal, homolysis occurs for covalent bond and the atom or group with unpaired electron that are formed, and free radical is very
Vivaciously, extremely unstable, it is easy to new free radical is generated with other substance reactions, often there is chain reaction, it is generated new
Free radical further react with matrix, so as to cause a large amount of consumption and the generation of more polyradical of matrix.
Under normal circumstances, the intracorporal free radical of people is in the dynamic equilibrium for constantly generating and removing.Exist in human body suitable
The free radical of amount be it is beneficial, facilitate the transmitting of energy, the exclusion of toxin can be participated in, meanwhile, to intracorporal bacterium and posting
It is infested etc. to have certain killing effect；However free radical generates excessive or removed slow, can attack life macromolecule substance and each
Kind cell, thereby results in body in the various damages of molecular level, cellular level and histoorgan level, accelerates the aging of body
Process simultaneously induces various diseases.Human body is also generating resistance free radical while being inevitably generated free radical naturally
Antioxidant, to offset free radical to the oxidative attacks of human body cell.Research has shown that the antioxidant system of human body is one
Can it is comparable with immune system, with improving and complicated function system, the oxidation resistant ability of body is stronger, healthy life
It is longer.The antioxidation of body, the balance that free radical can be kept to generate and eliminate have prevention disease and anti-aging etc. important
Meaning.
Although there are the anti-oxidative defense system of Scavenging active oxygen and free radical, internal existing superoxides discriminations in human body
Changing the antioxidases such as enzyme (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) can be to a certain degree
It is upper maintain in vivo " oxidative and anti-oxidative " balance, but due to solarization, excessive movement, the excessive, environmental pollution of pressure etc. it is bad because
Element is got worse, and people's interior free yl excessively has become a kind of universal phenomenon.By absorbing antioxidant into one from the external world
Step reduces interior free yl, has become a kind of important and necessary approach.
Currently, chemically synthesized antioxidant has biggish toxicity more, some is even carcinogenic, this makes people's pairing at anti-
Oxidant generates doubt and repels psychology, and there are biggish limitations for clinical application.It is found from resourceful natural products
Safety, low toxicity, effective antioxidant have become the emphasis of people's research.
Summary of the invention
Present invention solves the technical problem that being to provide a kind of safe and efficient antioxidant composition.
In view of this, this application provides a kind of antioxidant compositions, comprising:
Preferably, the antioxidant composition further includes the olive fruit of 0.1~5 parts by weight and the A Sa of 0.1~5 parts by weight
Yi Guo.
It preferably, include: the quinoa of 10~35 parts by weight in the antioxidant composition；The needle cherry of 0.5~4 parts by weight
Peach；The Bilberry fruit P.E of 0.3~2.5 parts by weight；The grape seed extract of 0.1~2 parts by weight；The west of 0.1~0.23 parts by weight
Cymbidium seed water extract；The roselle of 0.2~2 parts by weight, the olive fruit of 0.3~2 parts by weight, the A Sayi of 0.3~2 parts by weight
Fruit.
It preferably, include: the quinoa of 15 parts by weight in the antioxidant composition；The acerola concentrate of 0.5 parts by weight；0.3
The Bilberry fruit P.E of parts by weight；The grape seed extract of 0.1 parts by weight；The broccoli seed water extract of 0.23 parts by weight；0.3 weight
Measure the roselle of part.
Preferably, in the antioxidant composition further include: the olive fruit of 0.3 parts by weight, the A Sayi of 0.3 parts by weight
Fruit.
Present invention also provides a kind of anti-oxidation preparations, including antioxidant composition and auxiliary material described in above scheme.
Preferably, the auxiliary material includes the anticaking agent of 0.5~5 parts by weight and the flavoring agent of 0.5~5 parts by weight.
Preferably, the anticaking agent is selected from one or both of tricalcium phosphate and calcium silicates, and the flavoring agent is selected from sweet tea
One of taste agent, fruit powder, essence and regulating acid agent are a variety of.
Present invention also provides a kind of preparation methods of anti-oxidation preparation, comprising:
The each component of antioxidant composition described in above scheme is mixed with auxiliary material, obtains anti-oxidation preparation.
Anti-oxidation preparation described in antioxidant composition described in above scheme or above scheme prepare antioxidant food,
Application in drug or health care product.
This application provides a kind of antioxidant compositions comprising: the quinoa of 2~50 parts by weight, 0.1~5 parts by weight
Acerola concentrate, the Bilberry fruit P.E of 0.1~3 parts by weight, the grape seed extract of 0.01~3 parts by weight, 0.01~0.3 parts by weight
Broccoli seed water extract and 0.1~3 parts by weight roselle；It further include 0.1~5 in some preferred technical solutions
The A Sayi fruit of the olive fruit of parts by weight and 0.1~5 parts by weight.The raw material of above-mentioned antioxidant composition is naturally easy to get, to human body
It is highly-safe, and the synergistic effect between each component can be given full play to, comprehensive potency is high, and anti oxidation time is long, active component content
It is higher, there is good immunological regulation and antioxidation.On the other hand, antioxidant composition provided by the present application can be rushed directly
It is taken after mixing with liquid use, convenient and low manufacture cost.
Specific embodiment
For a further understanding of the present invention, the preferred embodiment of the invention is described below with reference to embodiment, still
It should be appreciated that these descriptions are only further explanation the features and advantages of the present invention, rather than to the claims in the present invention
Limitation.
For antioxidant functional food in the prior art, drug antioxidant effect is poor, has side effect, the scope of application to human body
Small problem, this application provides a kind of antioxidant composition, the antioxidant composition itself and decomposition product are nontoxic, steady
Qualitative good and edible organoleptic properties are good, convenient.Specifically, the embodiment of the invention provides a kind of antioxidant composition, packet
It includes:
In above-mentioned antioxidant composition, the quinoa originates in South America andes region, is print plus aborigines
Main conventional food has more than 5000~7000 years edible and plantation history, has unique, abundant, comprehensive nutritive value.Chenopodiaceae
Wheat is rich in polyphenols, is a kind of rare oxidation resistant plant.In the application antioxidant composition, the content of the quinoa
For 2~50 parts by weight, in a particular embodiment, the content of the quinoa is 10~35 parts by weight, more specifically, the quinoa
Content is 15~30 parts by weight.
Acerola concentrate is the current the most abundant fruit containing vitamin C known in the world, referred to as " king of vitamin C "；And
And the source vitamin C of acerola concentrate is natural vitamin C, is absorbed in human body relatively slowly, when the concentration in serum can be long
Between keep higher level, and to the effect of human body be other sources vitamin C it is incomparable.The acerola concentrate contains
Amount is 0.1~5 parts by weight, and in a particular embodiment, the content of the acerola concentrate is 0.5~4 parts by weight, more specifically, institute
The content for stating acerola concentrate is 1~3 parts by weight.
Cowberry is rich in anthocyanidin, the coloring matter in cowberry anthocyanidin, predominantly anthocyanidin -2- glucoside, anthocyanidin -
3- xyloside, anthocyanidin -3- galactoside, anthocyanidin -2- rhamnoside, delphinium -3- rhamnoside, delphinium -5- grape
Glucosides, 3-O- acyl original delphinidin, malvidin -3, bis- glucoside of 5- and 3,3- bis--acyl original flower extraction element etc..Cowberry anthocyanidin is advanced
Medicine intermediate helps to maintain capillary integrity and stablizes collagen, while being also good antioxidant.As a result,
Bilberry fruit P.E in the antioxidant composition of the application is mainly cowberry anthocyanidin, and content is 0.1~3 parts by weight, is being had
In body embodiment, the content of the Bilberry fruit P.E is 0.3~2.5 parts by weight, more specifically, the content of the Bilberry fruit P.E
For 1~2 parts by weight.
The glucosidase procyanidins (OPC) that grape seed extract is rich in are the most efficient antioxygens of the plant origin found so far
One of agent, anti-oxidant efficiency with super strength have the strength effect removing free radical, improving the immunity of the human body.Meanwhile Portugal
Grape seed essence bioflavonoid also rich in, be strength essence molecule, can be used for free radical resisting (free radical) and dimension
Protect the health of microfilament blood vessel.Herein described grape seed extract is grape seed extract well known to those skilled in the art, right
This application is not particularly limited.The content of the grape seed extract is 0.01~3 parts by weight, in a particular embodiment,
The content of the grape seed extract is 0.1~2 parts by weight, more specifically, the content of the grape seed extract is 0.5~
1.5 parts by weight.
Broccoli seed water extract contains glucorphanin, and glucorphanin is generated through the effect of human body intestinal canal flora or myrosin
Sulforaphen；Sulforaphen is a kind of effective II phase detoxication enzyme inducer, can protect injury caused by carcinogenic compound, be mesh
Anti-oxidant, the anti-cancer, the most significant isothiocyanic acid salt compound of anticancer activity of preceding discovery, and research both at home and abroad so far
In generally acknowledge vegetables in the highest effective component of anticancer activity.Epidemiology and live test show that sulforaphen can be effective
Reduce the generation of the cancers such as liver cancer, lung cancer, gastric cancer, prostate cancer, breast cancer, the carcinoma of the rectum, cancer of pancreas.West described herein is blue
Flower seed water extract mainly contains sulforaphen.The content of the broccoli seed water extract is 0.01~0.3 parts by weight, is being had
In body embodiment, the content of the broccoli seed water extract is 0.1~0.23 parts by weight, more specifically, the broccoli kind
The content of sub- water extract is 0.15~0.2 parts by weight.
Roselle is rich in a large amount of nutritional ingredients such as vitamin C, amino acid, organic acid, flavonoids anthocyanin, tocopherol, tool
Have elimination fatigue, clearing away summerheat the effect of, be also equipped with blood pressure lowering, relieving asthma, detoxify, diuresis and treatment heart disease, neurological disease
With multiple pharmacological effects and the medical application such as cancer.The content of the roselle is 0.1~3 parts by weight, in a particular embodiment,
The content of the roselle is 0.2~2 parts by weight, and more specifically, the content of the roselle is 0.3~1 parts by weight.
It further include the olive fruit of 0.1~5 parts by weight and the A Sayi of 0.1~5 parts by weight in the application antioxidant composition
Fruit.
Contain a large amount of olive polyphenol in olive fruit, olive polyphenol antiradical efficiency with super strength can protect
Cell and DNA prevent degenerative disease such as atherosclerosis, diabetes, nerve disease from the attack of active oxygen radical
The generation of disease reduces the expression of aging GAP-associated protein GAP, has the ability to delay senescence.In a particular embodiment, the olive fruit
Content be 0.2~3 parts by weight, more specifically, the content of the olive fruit is 0.3~2 parts by weight.
Contain a large amount of anthocyanidin, omega-3 unsaturated fatty acid, dietary fiber, vitamin, minerals in Ah Say fruit
Equal nutrients, wherein anthocyanidin content is 22 times of blueberry；Polyphenoils mass-energy that Ah Say fruit includes prevention diabetes and
Memory is improved, there is anti-aging, weight-reducing, reduce cholesterol, pre- anti-cancer and resistance building and other effects；Ah's Say fruit institute
The a large amount of polyphenoils and other mineral energies being rich in provide basic nutrient and to free radical resistings, can supplement because being moved through
The minerals iron lacked after acutely, alkali, vitamin etc. accelerate body digestion and using energy source, supply nutrition in time, inhibits spirit
Dispirited and skin aging.In a particular embodiment, the content of the A Sayi fruit is 0.2~3 parts by weight, more specifically, described
The content of Ah Say fruit is 0.3~2 parts by weight.
Antioxidant composition provided by the present application specifically includes: the quinoa of 15 parts by weight；The acerola concentrate of 0.5 parts by weight；
The Bilberry fruit P.E of 0.3 parts by weight；The grape seed extract of 0.1 parts by weight；The broccoli seed water extract of 0.23 parts by weight；
The roselle of 0.3 parts by weight, the olive fruit of 0.3 parts by weight, the A Sayi fruit of 0.3 parts by weight.
Present invention also provides a kind of anti-oxidation preparations comprising above-mentioned antioxidant composition and auxiliary material.
In this application, the dosage form of the anti-oxidation preparation is dosage form well known to those skilled in the art, to this application
It is not particularly limited.
In anti-oxidation preparation, the auxiliary material be it is well known to those skilled in the art, it is exemplary, can be anticaking agent and tune
One of taste agent is a variety of, more specifically, in the anti-oxidation preparation includes the anticaking agent and 0.5~5 of 0.5~5 parts by weight
The flavoring agent of parts by weight.The anticaking agent is selected from one or both of tricalcium phosphate and calcium silicates, and the flavoring agent is selected from sweet tea
One of taste agent, fruit powder, essence and regulating acid agent are a variety of；More specifically, the flavoring agent is chosen in particular from xylitol.
Present invention also provides a kind of preparation methods of anti-oxidation preparation, comprising:
The each component of antioxidant composition described in above scheme is mixed with auxiliary material to get anti-oxidation preparation is arrived.
It is above-mentioned prepare anti-oxidation preparation during, the quinoa is chosen in particular from the quinoa powder of shortening, the needle cherry
Peach is chosen in particular from acerola concentrate powder, and the olive fruit is chosen in particular from olive fruit powder, and the A Sayi fruit is chosen in particular from A Sayi fruit
Powder.
Above-mentioned antioxidant composition or anti-oxidation preparation provided by the invention can prepare antioxidant food, drug or health care
It is applied in food.
Antioxidant composition provided by the present application specifically includes quinoa, acerola concentrate, Bilberry fruit P.E, grape pip and extracts
Object, broccoli seed water extract and roselle, still further comprise olive fruit and A Sayi fruit, and specifically define said components
Content；Thus antioxidant composition provided by the present application has the advantage that 1) raw material is naturally easy to get, property safe to the human body
Height, proportion rationally, have a wide range of application；2) active component content is higher, has good immunological regulation and antioxidation；3) it is
A kind of combination of natural can give full play to the synergistic effect between raw material, and comprehensive potency is high, the antioxidation time
It is long；4) it can directly reconstitute and take, it is more convenient, and low manufacture cost.
For a further understanding of the present invention, antioxidant composition provided by the invention is carried out below with reference to embodiment detailed
Illustrate, protection scope of the present invention is not limited by the following examples.
Embodiment
Corresponding weight is accurately weighed according to the score of every kind of raw material in 2 comparative example of 1 embodiment of table and table, is uniformly mixed i.e.
Obtain composition；Table 1 is the compositional data table of antioxidant composition that 1~embodiment of embodiment 6 provides, table 2 be comparative example 1~
The compositional data table of 4 antioxidant compositions provided；
The compositional data table for the antioxidant composition that 1 1~embodiment of embodiment 6 of table provides
The compositional data table for the antioxidant composition that 2 comparative example 1~4 of table provides
| Group | Comparative example 1 | Comparative example 2 | Comparative example 3 | Comparative example 4 |
| Quinoa | 1 | 70 | 1 | 70 |
| Acerola concentrate powder | 0.05 | 10 | 0.05 | 10 |
| Bilberry fruit P.E | 0.05 | 5 | 0.05 | 5 |
| Grape seed extract | 0.001 | 5 | 0.001 | 5 |
| Broccoli seed water extract | 0.005 | 3 | 0.005 | 3 |
| Roselle | 0.005 | 5 | 0.005 | 5 |
| Olive fruit powder | 0 | 0 | 0.06 | 10 |
| Ah's Say fruit powder | 0 | 0 | 0.06 | 10 |
In order to further prove that advantages of the present invention, the present invention carry out antioxygen to the composition of above-described embodiment and comparative example
Change functional verification.The composition of Examples 1 to 6 is named as sample 1~6, and the composition of comparative example 1~4 is named as contrast sample 1
~4.Anti-oxidation function verification test is examined referring to anti-oxidation function in " health food is examined and assessment technique specification " (2003 editions)
Proved recipe method and operating instruction carry out.
(1) zoopery
Using 10 month female cleaning grade ICR mouse (40 ± 5g), it is randomly divided into a blank control group and 3 test samples
Product dosage group.3 test sample groups are divided into high dose group (8.1g/kg), middle dose group (2.7g/kg) and low dose group
(1.35g/kg), respectively 5 times, 10 times, 30 times of human body recommended amounts.The composition of various dose is given, it is once a day, continuous to fill
Stomach 30 days, animal is put to death at the end of experiment, surveys mda content, superoxide dismutase activity and paddy Guang ammonia peptide peroxidase
Vigor.
(2) compliance test result
Data are indicated using mean ± standard deviation, carry out one-way analysis of variance, it is poor to indicate that there are conspicuousnesses with P < 0.05
It is different.
Influence tables of data of 3 given the test agent of table to malonaldehyde in mice serum (MDA) content
Note: compared with blank control group,*P < 0.05；**P < 0.01.
Influence tables of data of 4 given the test agent of table to superoxide dismutase in murine liver tissue (SOD) vigor
Note: compared with blank control group,*P < 0.05；**P < 0.01.
Influence tables of data of 5 given the test agent of table to paddy Guang ammonia peptide peroxidase (GSH-Px) vigor in murine liver tissue
Note: compared with blank control group,*P < 0.05；**P < 0.01.
By 3~table of table 5 it is found that compared with the control group, the composition that sample 1~6 is prepared can significantly reduce mouse
Serum malondialdehyde content, while being obviously improved liver superoxide dismutase vigor and paddy Guang ammonia peptide peroxidase activity (*
P < 0.05；* P < 0.01)；The result of contrast sample 1~5 illustrates only without significant difference using technical scheme system
Standby obtained composition, just has good antioxidant effect.
It can be seen that antioxidant composition provided by the present application from above-mentioned test result, including quinoa, acerola concentrate, more
Tangerine extract, grape seed extract, broccoli seed water extract and roselle can make to produce between each ingredient by the proportion of science
Raw synergistic function, makes composition have good antioxidant effect；4~6 effect data can be seen that in conjunction with the embodiments
One or both of olive fruit powder and A Sayi fruit powder are further added, can be further improved the effect of composition.
The above description of the embodiment is only used to help understand the method for the present invention and its core ideas.It should be pointed out that pair
For those skilled in the art, without departing from the principle of the present invention, the present invention can also be carried out
Some improvements and modifications, these improvements and modifications also fall within the scope of protection of the claims of the present invention.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest scope of cause.
Claims (10)
1. a kind of antioxidant composition, comprising:
2. antioxidant composition according to claim 1, which is characterized in that the antioxidant composition further includes 0.1~5
The A Sayi fruit of the olive fruit of parts by weight and 0.1~5 parts by weight.
3. antioxidant composition according to claim 2, which is characterized in that include: 10 in the antioxidant composition~
The quinoa of 35 parts by weight；The acerola concentrate of 0.5~4 parts by weight；The Bilberry fruit P.E of 0.3~2.5 parts by weight；0.1~2 parts by weight
Grape seed extract；The broccoli seed water extract of 0.1~0.23 parts by weight；The roselle of 0.2~2 parts by weight, 0.3~2
The olive fruit of parts by weight, the A Sayi fruit of 0.3~2 parts by weight.
4. antioxidant composition according to claim 1, which is characterized in that include: 15 weights in the antioxidant composition
Measure the quinoa of part；The acerola concentrate of 0.5 parts by weight；The Bilberry fruit P.E of 0.3 parts by weight；The grape seed extract of 0.1 parts by weight；
The broccoli seed water extract of 0.23 parts by weight；The roselle of 0.3 parts by weight.
5. antioxidant composition according to claim 1 or 4, which is characterized in that in the antioxidant composition further include:
The olive fruit of 0.3 parts by weight, the A Sayi fruit of 0.3 parts by weight.
6. a kind of anti-oxidation preparation, including the described in any item antioxidant compositions of Claims 1 to 5 and auxiliary material.
7. anti-oxidation preparation according to claim 6, which is characterized in that the auxiliary material includes the resistive connection of 0.5~5 parts by weight
The flavoring agent of agent and 0.5~5 parts by weight.
8. anti-oxidation preparation according to claim 7, which is characterized in that the anticaking agent is selected from tricalcium phosphate and calcium silicates
One or both of, the flavoring agent is selected from one of sweetener, fruit powder, essence and regulating acid agent or a variety of.
9. a kind of preparation method of anti-oxidation preparation, comprising:
The each component of the described in any item antioxidant compositions of Claims 1 to 5 is mixed with auxiliary material, obtains anti-oxidation preparation.
10. the described in any item antioxidant compositions of Claims 1 to 5 or the described in any item anti-oxidant systems of claim 6~8
Agent is preparing the application in antioxidant food, drug or health food.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110269221A (en) * | 2019-07-30 | 2019-09-24 | 纯真植物营养素研究院(西安)有限公司 | Plant nutrient promotor composition, preparation method and anti-oxidation function food |
| CN111011838A (en) * | 2019-12-10 | 2020-04-17 | 广东绿宝堂健康科技有限公司 | Food composition and preparation method thereof |
| CN112869073A (en) * | 2021-03-05 | 2021-06-01 | 郭宝叶 | Chinese medicinal composition comprising fruits and vegetables for improving human body function and removing harmful toxin, and its preparation method |
| WO2022110090A1 (en) * | 2020-11-29 | 2022-06-02 | 江苏康神医药保健品有限公司 | Anti-ageing health-care product |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106551383A (en) * | 2015-09-21 | 2017-04-05 | 北京倍和阳光科技发展有限公司 | A kind of antioxidant composition of strong anti-oxidation |
| CN107997155A (en) * | 2017-12-01 | 2018-05-08 | 北京斯利安药业有限公司 | A kind of composition, its application and product that is anti-oxidant, improving memory |
| CN108402462A (en) * | 2018-02-27 | 2018-08-17 | 北京斯利安药业有限公司 | A kind of composition, its application ease up physical fatigue, strengthen immunity product |
-
2018
- 2018-10-26 CN CN201811258222.8A patent/CN109329727A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106551383A (en) * | 2015-09-21 | 2017-04-05 | 北京倍和阳光科技发展有限公司 | A kind of antioxidant composition of strong anti-oxidation |
| CN107997155A (en) * | 2017-12-01 | 2018-05-08 | 北京斯利安药业有限公司 | A kind of composition, its application and product that is anti-oxidant, improving memory |
| CN108402462A (en) * | 2018-02-27 | 2018-08-17 | 北京斯利安药业有限公司 | A kind of composition, its application ease up physical fatigue, strengthen immunity product |
Non-Patent Citations (2)
| Title |
|---|
| 白鸿: "《保健食品功效成分检测方法》", 31 May 2011 * |
| 程嘉艺: "《药食同源中药材药理研究与应用》", 31 March 2018 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110269221A (en) * | 2019-07-30 | 2019-09-24 | 纯真植物营养素研究院(西安)有限公司 | Plant nutrient promotor composition, preparation method and anti-oxidation function food |
| CN111011838A (en) * | 2019-12-10 | 2020-04-17 | 广东绿宝堂健康科技有限公司 | Food composition and preparation method thereof |
| WO2022110090A1 (en) * | 2020-11-29 | 2022-06-02 | 江苏康神医药保健品有限公司 | Anti-ageing health-care product |
| CN112869073A (en) * | 2021-03-05 | 2021-06-01 | 郭宝叶 | Chinese medicinal composition comprising fruits and vegetables for improving human body function and removing harmful toxin, and its preparation method |
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