CN109315768A - A kind of health composition of anti-aging and preparation method thereof - Google Patents
A kind of health composition of anti-aging and preparation method thereof Download PDFInfo
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- CN109315768A CN109315768A CN201811011651.5A CN201811011651A CN109315768A CN 109315768 A CN109315768 A CN 109315768A CN 201811011651 A CN201811011651 A CN 201811011651A CN 109315768 A CN109315768 A CN 109315768A
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- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 27
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- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims abstract description 18
- 235000021014 blueberries Nutrition 0.000 claims abstract description 18
- 235000009754 Vitis X bourquina Nutrition 0.000 claims abstract description 17
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- 235000014787 Vitis vinifera Nutrition 0.000 claims abstract description 17
- 102000004506 Blood Proteins Human genes 0.000 claims abstract description 14
- 108010017384 Blood Proteins Proteins 0.000 claims abstract description 14
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- 238000007796 conventional method Methods 0.000 claims description 7
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- 239000008280 blood Substances 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 238000011049 filling Methods 0.000 claims description 3
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- 210000002381 plasma Anatomy 0.000 claims description 3
- 239000003146 anticoagulant agent Substances 0.000 claims description 2
- 229940127219 anticoagulant drug Drugs 0.000 claims description 2
- 241000227653 Lycopersicon Species 0.000 claims 4
- 229940087559 grape seed Drugs 0.000 claims 1
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- 239000000463 material Substances 0.000 abstract description 2
- -1 anti-aging effects Substances 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 description 18
- 241000700159 Rattus Species 0.000 description 15
- 230000032683 aging Effects 0.000 description 15
- 102000019197 Superoxide Dismutase Human genes 0.000 description 13
- 108010012715 Superoxide dismutase Proteins 0.000 description 13
- 241000219095 Vitis Species 0.000 description 13
- 210000005013 brain tissue Anatomy 0.000 description 12
- 102000010909 Monoamine Oxidase Human genes 0.000 description 10
- 108010062431 Monoamine oxidase Proteins 0.000 description 10
- 239000000047 product Substances 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 238000000034 method Methods 0.000 description 7
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- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
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- 108700016172 Glutathione peroxidases Proteins 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 238000003149 assay kit Methods 0.000 description 2
- 238000005660 chlorination reaction Methods 0.000 description 2
- 235000013402 health food Nutrition 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 210000004279 orbit Anatomy 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- KIUMMUBSPKGMOY-UHFFFAOYSA-N 3,3'-Dithiobis(6-nitrobenzoic acid) Chemical compound C1=C([N+]([O-])=O)C(C(=O)O)=CC(SSC=2C=C(C(=CC=2)[N+]([O-])=O)C(O)=O)=C1 KIUMMUBSPKGMOY-UHFFFAOYSA-N 0.000 description 1
- 240000002900 Arthrospira platensis Species 0.000 description 1
- 235000016425 Arthrospira platensis Nutrition 0.000 description 1
- 235000001258 Cinchona calisaya Nutrition 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 240000001341 Reynoutria japonica Species 0.000 description 1
- 235000018167 Reynoutria japonica Nutrition 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 210000003710 cerebral cortex Anatomy 0.000 description 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000002795 fluorescence method Methods 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 235000020710 ginseng extract Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 235000010204 pine bark Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 229960000948 quinine Drugs 0.000 description 1
- 229940119485 safflower extract Drugs 0.000 description 1
- 230000009758 senescence Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229940082787 spirulina Drugs 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001103 thalamus Anatomy 0.000 description 1
- 235000021404 traditional food Nutrition 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
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- 229940046009 vitamin E Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of health composition of anti-aging, the composition includes the raw material of following parts by weight: 10-30 parts of tomato, 10-30 parts of blueberry, 5-10 parts of Swine plasma protein, 3-5 parts of grape pip.Meanwhile the invention also discloses the preparation methods of the composition.Health composition of the present invention has apparent anti-oxidant, anti-aging effects, and material combination is precise and appropriate, synergistic, without any side effects, can take for a long time.
Description
Technical field
The present invention relates to a kind of health foods more particularly to a kind of health composition of anti-aging and preparation method thereof.
Background technique
Aging refer to body the physiology and psychological fitness progressive of environment are reduced, gradually phenomenon deathward.
Aging can be divided into two class of physiological aging and pathological seaility.Physiological aging is the physiology sexual involution mistake occurred after the maturity period
Journey, pathological seaility are the senile variations caused by various foeign elements (including various diseases).The two is practical to be difficult
It distinguishes.In short, aging is the inevitable outcome of many pathology, physiology and noematic comprehensive function, it is that individual growth is developed most
The biology in stage, psychology process afterwards.
Occur the drug and health food of many anti-agings currently on the market, it is special that some of them has declared invention
Benefit, if patent No. ZL200610044379.1 discloses a kind of SOD health composition, which is to utilize SOD and VC, VE, flower
Powder and the fleece-flower root are compounded with Rhizoma Polygonati extract mixing, obtain having anti-oxidant, anti-aging, antifatigue, the immune, lipid-loweringing of enhancing etc.
The health composition of function；Patent No. ZL201110254795.5 discloses a kind of SOD complex capsule and preparation method thereof, this is specially
Benefit selection SOD, ginseng extract, pearl powder, Radix Codonopsis extract, safflower extract, Herb Gynostemmae Pentaphylli extract spirulina, pine bark mention
It takes and is combined with polysaccharides, enteric capsulation is made, product, which has, to delay senescence, and enhances the effect of immunity of organisms.These are specially
Benefit apply involved in product formula be substantially Chinese herbal medicine extract or be chemical synthesis antioxidant (such as vitamin C
And vitamin E) compounded with Chinese herbal medicine extract, this kind of product has the health-care efficacies such as certain anti-oxidant, anti-aging, but
Long-term use can generate certain side effect.Therefore, prior art in terms of product efficacy and saferry Shortcomings it
Place.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of guarantors of anti-aging easy to use, without side-effects to human body
Strong composition.
Another technical problem to be solved by this invention is to provide the preparation method of the health composition of the anti-aging.
To solve the above problems, a kind of health composition of anti-aging of the present invention, it is characterised in that: it contain as
The raw material of lower weight proportion: 10-30 parts of tomato, 10-30 parts of blueberry, 5-10 parts of Swine plasma protein, 3-5 parts of grape pip.
The tomato, blueberry, grape pip are the dry products obtained after its fresh goods is freeze-dried, compatibility dosage with
Dry product meter.
The Swine plasma protein is the blood plasma liquid that fresh anticoagulant pig blood is centrifuged, it is freeze-dried and
At plasma protein powder.
The composition is solid pharmaceutical preparation.
The solid pharmaceutical preparation is one of granule, tablet, capsule.
A kind of preparation method of the health composition of anti-aging as described above, it is characterised in that: weigh according to the ratio first
Then raw material carries out micro mist to tomato, blueberry, grape pip, obtain tomato, blueberry, grape pip powder, then by powder and blood plasma
Albumen powder is uniformly mixed, and is pelletized according to a conventional method, is finally dried according to a conventional method, whole grain, total mix obtain intermediate, should
Intermediate is packed after pack or capsule filling or tabletting up to oral solid formulation finished product.
Compared with the prior art, the present invention has the following advantages:
(1) raw material used in the present invention is all traditional food, full of nutrition, nontoxic, is had significant anti-oxidant, anti-ageing
Old effect.
(2) present invention uses oral solid dose forms, and quality is stablized, and convenient to take, dosage is more according to human body requirements
It takes without any side effects to human body.
Specific embodiment
Embodiment 1:
A kind of health composition of anti-aging, the composition contain the raw material of following weight proportion: 30 parts of tomato, 20 parts of blueberry,
5 parts of Swine plasma protein, 5 parts of grape pip.
The preparation method of the health composition of the anti-aging is: weigh raw material according to the ratio first, then to tomato, blueberry,
Grape pip carries out micro mist, obtain tomato, blueberry, grape pip powder, then powder is uniformly mixed with plasma protein powder, routinely
Method is pelletized, and is finally dried according to a conventional method, whole grain, total mix obtain intermediate, which fills out through pack or capsule
Fill or tabletting after, pack up to oral solid formulation finished product.
Solid pharmaceutical preparation is one of granule, tablet, capsule.
Instructions of taking and dosage: warm water is taken after mixing it with water or buccal (tablet), and adult daily 3 times, each 5g.
Embodiment 2:
A kind of health composition of anti-aging, the composition contain the raw material of following weight proportion: 20 parts of tomato, 10 parts of blueberry,
8 parts of Swine plasma protein, 3 parts of grape pip.
The preparation method of the health composition of the anti-aging is: weigh raw material according to the ratio first, then to tomato, blueberry,
Grape pip carries out micro mist, obtain tomato, blueberry, grape pip powder, then powder is uniformly mixed with plasma protein powder, routinely
Method is pelletized, and is finally dried according to a conventional method, whole grain, total mix obtain intermediate, which fills out through pack or capsule
Fill or tabletting after, pack up to oral solid formulation finished product.
Solid pharmaceutical preparation is one of granule, tablet, capsule.
Instructions of taking and dosage: warm water is taken after mixing it with water or buccal (tablet), and adult daily 3 times, each 5g.
Embodiment 3:
A kind of health composition of anti-aging, the composition contain the raw material of following weight proportion: 10 parts of tomato, 30 parts of blueberry,
10 parts of Swine plasma protein, 4 parts of grape pip.
The preparation method of the health composition of the anti-aging is: weigh raw material according to the ratio first, then to tomato, blueberry,
Grape pip carries out micro mist, obtain tomato, blueberry, grape pip powder, then powder is uniformly mixed with plasma protein powder, routinely
Method is pelletized, and is finally dried according to a conventional method, whole grain, total mix obtain intermediate, which fills out through pack or capsule
Fill or tabletting after, pack up to oral solid formulation finished product.
Solid pharmaceutical preparation is one of granule, tablet, capsule.
Instructions of taking and dosage: warm water is taken after mixing it with water or buccal (tablet), and adult daily 3 times, each 5g.
Present composition research on anti-senescence
Influence to aging rats metabolite and relevant enzyme caused by D- galactolipin
1. experimental material
1.1 animal SD rats, half male and half female, 6~7 monthly ages, 150~200g of weight, by the limited public affairs of Shanghai Si Laike experimental animal
Department provides.
1.2 drugs and main agents
Drug:
Using the health composition granule of the resulting anti-aging of embodiment 1 as trial drug.
Reagent:
Superoxide dismutase (SOD) kit (Bioengineering Research Institute's production is built up in Nanjing)
Glutathione peroxidase (GSH-Px) kit (Bioengineering Research Institute's offer is built up in Nanjing)
Monoamine oxidase kit (MAO) (Nanjing is built up Bioengineering Research Institute's production and provided)
Lipofuscin kit (Nanjing is built up Bioengineering Research Institute's production and provided)
D- galactolipin (offer of Jiangsu Peng Xiang biological medicine Co., Ltd), it is spare at 1% concentration with normal saline.
1.3 instrument
960CRT sepectrophotofluorometer, 7560 ultraviolet specrophotometers, constant water bath box, centrifuge.
2. experimental method and result
2.1 groupings and administration
SD rat 50 of 6-7 monthly age are chosen in this experiment, and half male and half female, weight 180-220g is randomly divided into 5 groups, respectively empty
Three white control group, model control group, trial drug (high, medium and low) dosage groups, every group 10.High, medium and low group is pressed respectively
The medication amount gastric infusion (20 times, 10 times and 5 times that are equivalent to the every consumption per day of human body) of 5.0g/kg, 2.5g/kg, 1.25g/kg,
One time a day, the weight distilled water such as blank control group and the daily stomach-filling of model control group, successive administration 30 days.
The modeling of 2.2 animals
While administration, aged animal model is established according to literature method, model control group and administration group equal the nape of the neck skin daily
The physiological saline of equivalent is subcutaneously injected in lower injection 1%D- galactose injection 50mg/kg, blank control group in the nape of the neck daily,
Continuous injection 30 days.
The measurement (fluorescence method) of 2.3 brain lipofuscin (LPF) contents
The 2nd day after drug withdrawal, rat takes off backbone and puts to death, and takes cerebral cortex 200mg rapidly, chlorination imitation-carbinol (2:1) 4ml. is even
Slurry 3090 revs/min, vibrates 3 minutes, is centrifuged lO minutes, takes subnatant, be transferred to another test tube, chlorination is imitated to 5ml, ultraviolet lamp
Lower irradiation 30 seconds, using its fluorescence intensity of fluorescent spectrophotometer measuring, excitation wavelength 360nm, launch wavelength 450nm, with 0.1ug/
The quinine liquid of ml is standard, measures the fluorescence intensity of sample, then calculate the content of lipofuscin, and it is poor to compare each group whether there is or not conspicuousnesses
It is different.It the results are shown in Table 1:
As a result indicate: aging rats model control group brain tissue LPF content caused by D- galactolipin increases, and is extremely significantly higher than blank
Control group (P < 0.01), the LPF content that each dosage group is administered significantly reduce (P < 0.05) compared with model control group.Explanation
The present composition can reduce the content of LPF in D- gal Aging rat brain.
The measurement (Huang looks sidelong at purine enzymatic measurement) of superoxide dismutase (SOD) content in 2.4 serum and brain tissue
The 2nd day after drug withdrawal, eye socket takes blood, takes serum spare, and rat takes off backbone and puts to death, and takes out brain rapidly, removal thalamus, small
Brain, oblongata, to be configured to 1% brain tissue homogenate under PH7.4 phosphate buffer ice bath, (1500 turns/min, take supernatant for centrifugation
It is spare.Serum and each 30ul of supernatant are taken, the reagent in kit is sequentially added, room temperature 10 minutes, OD value is surveyed at 550nm,
Each group SOD is calculated, comparing each group has that there was no significant difference.It the results are shown in Table 2:
As a result it indicates: aging rats model control group serum caused by D- galactolipin and the decline of brain tissue SOD content, it is substantially less than empty
White control group (P < 0.05), is administered each dosage group compared with model control group, and each dosage group serum is administered and brain tissue SOD contains
Amount is all remarkably higher than model control group (P < 0.05).Illustrate that the present composition has and improves D- gal Aging rat blood serum
With the active effect of brain tissue SOD.
The measurement (DTNB method) of 2.5 serum and brain tissue Glutathione Peroxidase (GSH-Px) content
GSH-Px assay kit is taken, serum and 1% each 0.2ml of brain tissue homogenate's supernatant is taken, sequentially adds in kit
Reagent after mixing 1 minute, surveys OD value at 422nm, calculates each group GSH-Px, comparing each group, there was no significant difference.As a result see
Table 3:
As a result indicate: aging rats model control group serum caused by D- galactolipin and brain tissue GSH-Px activity reduce, significant low
In blank control group (P < 0.05), each dosage group is administered compared with model control group, each dosage group GSH-Px in serum activity is administered
Significantly increase (P < 0.05), and has certain dose-effect relationship；High dose group brain GSH-Px activity is shown compared with model control group
Work increases (P < 0.05).Illustrate that the present composition is improved D- gal Aging rat blood serum and brain tissue GSH-Px activity
Effect.
The measurement of monoamine oxidase (MA0) in 2.6 serum
The 2nd day after drug withdrawal, eye socket takes blood, using MAO assay kit, takes serum 200ul, sequentially adds the examination in kit
Agent, 56 DEG C keep the temperature 30 minutes, OD value are surveyed in 470nm at, calculating each group MAO, comparing each group has that there was no significant difference.As a result see
Table 4:
As a result indicate: aging rats model caused by D- galactolipin increases serum MAO activity according to group, is extremely significantly higher than blank pair
According to group (P < 0.01), each dosage group is administered compared with model control group, high dose group and middle dose group MAO activity significantly reduce
(P < 0.05).Illustrate that the present composition can reduce the content of MAO in serum.
The experiment results show that pharmaceutical composition of the present invention can reduce the content of LPF in aging rats brain, improve rat
Serum and brain tissue SOD activity improve aging rats serum and brain tissue GSH-Px activity, the content for reducing MAO in serum, tool
There is anti-aging.
Claims (6)
1. a kind of health composition of anti-aging, it is characterised in that: it contains the raw material of following weight proportion: 10-30 parts of tomato,
10-30 parts of blueberry, 5-10 parts of Swine plasma protein, 3-5 parts of grape pip.
2. a kind of health composition of anti-aging according to claim 1, it is characterised in that: the tomato, blueberry, Portugal
Grape seed is the dry product obtained after its fresh goods is freeze-dried, and the dosage of compatibility is in terms of dry product.
3. a kind of health composition of anti-aging according to claim 1, it is characterised in that: the Swine plasma protein
The blood plasma liquid that fresh anticoagulant pig blood is centrifuged, it is freeze-dried made of plasma protein powder.
4. a kind of health composition of anti-aging according to claim 1, it is characterised in that: the composition is solid system
Agent.
5. according to right want 4 described in a kind of health composition of anti-aging, it is characterised in that: the solid pharmaceutical preparation be particle
One of agent, tablet, capsule.
6. a kind of preparation method of the health composition of the described in any item anti-agings of claim 1-5, it is characterised in that: first
Weigh raw material according to the ratio, then to tomato, blueberry, grape pip carry out micro mist, obtain tomato, blueberry, grape pip powder, then will
Powder is uniformly mixed with plasma protein powder, is pelletized according to a conventional method, is finally dried according to a conventional method, whole grain, total mix
Intermediate is obtained, which packs after pack or capsule filling or tabletting up to oral solid formulation finished product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811011651.5A CN109315768A (en) | 2018-08-31 | 2018-08-31 | A kind of health composition of anti-aging and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN109315768A true CN109315768A (en) | 2019-02-12 |
Family
ID=65263492
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111903966A (en) * | 2020-07-23 | 2020-11-10 | 重庆师范大学 | A health product with antioxidant and antiaging effects, and its preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111903966A (en) * | 2020-07-23 | 2020-11-10 | 重庆师范大学 | A health product with antioxidant and antiaging effects, and its preparation method |
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