CN109288899A - A kind of drug and preparation method thereof for treating the cancer of the brain - Google Patents
A kind of drug and preparation method thereof for treating the cancer of the brain Download PDFInfo
- Publication number
- CN109288899A CN109288899A CN201811430347.4A CN201811430347A CN109288899A CN 109288899 A CN109288899 A CN 109288899A CN 201811430347 A CN201811430347 A CN 201811430347A CN 109288899 A CN109288899 A CN 109288899A
- Authority
- CN
- China
- Prior art keywords
- weight
- parts
- drug
- brain
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 84
- 229940079593 drug Drugs 0.000 title claims abstract description 49
- 208000003174 Brain Neoplasms Diseases 0.000 title claims abstract description 45
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 239000002994 raw material Substances 0.000 claims abstract description 18
- 241000208340 Araliaceae Species 0.000 claims abstract description 17
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 17
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 17
- 235000008434 ginseng Nutrition 0.000 claims abstract description 17
- 241000227129 Aconitum Species 0.000 claims abstract description 15
- 240000001829 Catharanthus roseus Species 0.000 claims abstract description 15
- 241000258920 Chilopoda Species 0.000 claims abstract description 14
- 241000545744 Hirudinea Species 0.000 claims abstract description 14
- 241000522620 Scorpio Species 0.000 claims abstract description 14
- 239000009490 scorpio Substances 0.000 claims abstract description 14
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 13
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 13
- 239000006187 pill Substances 0.000 claims description 21
- 239000000126 substance Substances 0.000 claims description 15
- 241000271039 Agkistrodon Species 0.000 claims description 13
- 241000717739 Boswellia sacra Species 0.000 claims description 13
- 241000282817 Bovidae Species 0.000 claims description 13
- 239000004863 Frankincense Substances 0.000 claims description 13
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 13
- 241000180649 Panax notoginseng Species 0.000 claims description 13
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 13
- 241000107360 Vincetoxicum glaucescens Species 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 13
- 241001339782 Scapharca broughtonii Species 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- 230000008595 infiltration Effects 0.000 claims description 6
- 238000001764 infiltration Methods 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 5
- 235000012907 honey Nutrition 0.000 claims description 5
- 238000007654 immersion Methods 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 244000061520 Angelica archangelica Species 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 15
- 206010028980 Neoplasm Diseases 0.000 abstract description 13
- 201000010099 disease Diseases 0.000 abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 11
- 231100000614 poison Toxicity 0.000 abstract description 10
- 201000011510 cancer Diseases 0.000 abstract description 9
- 210000000988 bone and bone Anatomy 0.000 abstract description 7
- 241000721047 Danaus plexippus Species 0.000 abstract description 4
- 230000003902 lesion Effects 0.000 abstract description 4
- 239000003440 toxic substance Substances 0.000 abstract description 3
- 238000001784 detoxification Methods 0.000 abstract description 2
- 238000012377 drug delivery Methods 0.000 abstract description 2
- 241000411851 herbal medicine Species 0.000 abstract description 2
- 238000002651 drug therapy Methods 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 description 14
- 235000019634 flavors Nutrition 0.000 description 14
- 208000002193 Pain Diseases 0.000 description 13
- 230000001737 promoting effect Effects 0.000 description 13
- 230000036407 pain Effects 0.000 description 12
- 241000125175 Angelica Species 0.000 description 11
- 210000004369 blood Anatomy 0.000 description 11
- 239000008280 blood Substances 0.000 description 10
- 206010019233 Headaches Diseases 0.000 description 8
- 206010042674 Swelling Diseases 0.000 description 8
- 210000001015 abdomen Anatomy 0.000 description 8
- 231100000869 headache Toxicity 0.000 description 8
- 230000008961 swelling Effects 0.000 description 8
- 210000004556 brain Anatomy 0.000 description 7
- 230000036461 convulsion Effects 0.000 description 7
- 206010010904 Convulsion Diseases 0.000 description 6
- 230000008901 benefit Effects 0.000 description 6
- 235000009508 confectionery Nutrition 0.000 description 6
- 210000003205 muscle Anatomy 0.000 description 6
- 230000001717 pathogenic effect Effects 0.000 description 6
- 206010007247 Carbuncle Diseases 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 5
- 208000025865 Ulcer Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 239000006071 cream Substances 0.000 description 5
- 230000005906 menstruation Effects 0.000 description 5
- 231100000862 numbness Toxicity 0.000 description 5
- 239000002574 poison Substances 0.000 description 5
- 231100000331 toxic Toxicity 0.000 description 5
- 230000002588 toxic effect Effects 0.000 description 5
- 231100000397 ulcer Toxicity 0.000 description 5
- 206010000077 Abdominal mass Diseases 0.000 description 4
- 201000009030 Carcinoma Diseases 0.000 description 4
- 206010019468 Hemiplegia Diseases 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 208000005392 Spasm Diseases 0.000 description 4
- 230000000202 analgesic effect Effects 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 201000007227 lymph node tuberculosis Diseases 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 208000006820 Arthralgia Diseases 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 3
- 206010020772 Hypertension Diseases 0.000 description 3
- 206010062575 Muscle contracture Diseases 0.000 description 3
- 206010028347 Muscle twitching Diseases 0.000 description 3
- 206010036790 Productive cough Diseases 0.000 description 3
- 241000219780 Pueraria Species 0.000 description 3
- 206010043376 Tetanus Diseases 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 238000009825 accumulation Methods 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 208000006111 contracture Diseases 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 206010015037 epilepsy Diseases 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 210000003128 head Anatomy 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- 235000021251 pulses Nutrition 0.000 description 3
- 206010039073 rheumatoid arthritis Diseases 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 208000024794 sputum Diseases 0.000 description 3
- 210000003802 sputum Anatomy 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 description 2
- 241000234282 Allium Species 0.000 description 2
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 2
- 240000002234 Allium sativum Species 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 206010018498 Goitre Diseases 0.000 description 2
- 201000005505 Measles Diseases 0.000 description 2
- 208000037093 Menstruation Disturbances Diseases 0.000 description 2
- 206010027339 Menstruation irregular Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- 208000001431 Psychomotor Agitation Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 244000088415 Raphanus sativus Species 0.000 description 2
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 description 2
- 206010038743 Restlessness Diseases 0.000 description 2
- 208000025747 Rheumatic disease Diseases 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- 208000010513 Stupor Diseases 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- 240000004922 Vigna radiata Species 0.000 description 2
- 235000010721 Vigna radiata var radiata Nutrition 0.000 description 2
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 244000273928 Zingiber officinale Species 0.000 description 2
- 235000006886 Zingiber officinale Nutrition 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 230000001093 anti-cancer Effects 0.000 description 2
- 230000001663 anti-spastic effect Effects 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000001174 ascending effect Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000002512 chemotherapy Methods 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 201000003444 follicular lymphoma Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 235000004611 garlic Nutrition 0.000 description 2
- 235000008397 ginger Nutrition 0.000 description 2
- 208000021760 high fever Diseases 0.000 description 2
- 201000001881 impotence Diseases 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000003119 painkilling effect Effects 0.000 description 2
- 230000007170 pathology Effects 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000001959 radiotherapy Methods 0.000 description 2
- 230000000552 rheumatic effect Effects 0.000 description 2
- 208000005687 scabies Diseases 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 230000001568 sexual effect Effects 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 208000006332 Choriocarcinoma Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010016945 Fontanelle bulging Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010020601 Hyperchlorhydria Diseases 0.000 description 1
- 206010022773 Intracranial pressure increased Diseases 0.000 description 1
- 206010024229 Leprosy Diseases 0.000 description 1
- 206010025323 Lymphomas Diseases 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 206010028836 Neck pain Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 208000006268 Sarcoma 180 Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 206010046814 Uterine prolapse Diseases 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000002082 anti-convulsion Effects 0.000 description 1
- 230000001147 anti-toxic effect Effects 0.000 description 1
- 201000007201 aphasia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019636 bitter flavor Nutrition 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 206010007625 cardiogenic shock Diseases 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000019771 cognition Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 201000009941 intracranial hypertension Diseases 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 210000001767 medulla oblongata Anatomy 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 208000018962 mouth sore Diseases 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 201000010727 rectal prolapse Diseases 0.000 description 1
- 210000001034 respiratory center Anatomy 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 208000011571 secondary malignant neoplasm Diseases 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 210000001186 vagus nerve Anatomy 0.000 description 1
- 230000000283 vasomotion Effects 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/648—Myriapods, e.g. centipedes or millipedes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Insects & Arthropods (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Marine Sciences & Fisheries (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Animal Husbandry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of drugs and preparation method thereof for treating the cancer of the brain, the drug of the treatment cancer of the brain is raw material by using the 22 pleasant impression Chinese herbal medicine such as ginseng, monkshood, pueraria lobata, cimicifugae foetidae, catharanthus roseus, spina gleditsiae, centipede, scorpio, leech, Eupolyphoge sinensis, Fructus Liquidambaris, Radix Glycyrrhizae and carries out appropriate weight proportion, using ginseng as monarch drug in a prescription, the full side of commander, righting is got rid of evils, monkshood is ministerial drug, and cimicifugae foetidae aids pueraria lobata, resultant force lifting disease uplink;Catharanthus roseus, spina gleditsiae have significant antitumaous effect;The medicine of Fructus Liquidambaris and a variety of Zhuo Li reach lesion combined into assistant, drug delivery power, by malicious evil external out;Radix Glycyrrhizae removing toxic substances, and coordinating the drug actions of a prescription, and become making for many medicines in side.Monarch minister, helps, makes generous heavy medicine, plays to search altogether and be picked a bone, and product of assaulting fortified position brokenly, detoxification swings cancer, and heresy is enabled to disappear positive length, the definite curative effect that disease goes people to pacify.Data are shown: 81% or more the effective percentage of the drug therapy cancer of the brain of the present invention, obvious effective rate 69%, cure rate 63%, good effect, and cure rate is high.
Description
Technical field
The present invention relates to technical field of pharmaceuticals, and in particular to a kind of drug and preparation method thereof for treating the cancer of the brain.
Background technique
The cancer of the brain refers to the neoformation for being grown in cranial cavity, also known as malignant brain tumor, can originating from brain, meninx, nerve, blood vessel and
Brain attachment, or formed by its hetero-organization of body or the Malignant tumor of bonal metastasis Intracranial invasion of internal organs.Including being occurred by brain parenchym
Primary brain cancer and the secondary cancer of the brain of encephalic is transferred to by other positions of body.Malignant brain tumor growth is very fast, no coating, boundary
Limit it is unobvious, be in infiltrative growth, poorly differentiated.Because the profile of cranial cavity is bone entirely, if brain gives birth to struma, can make
Cranium cavity pressure increases, thus generates headache, and vomiting, sight is unclear, knots, and stupor, state of consciousness changes (drowsiness, stupor) also
Or pupil lesion etc..Malignant brain tumor advanced stage, tumour cell can also be transferred to body other organs.In child, intracranial pressure
Increase may also lead to skull diameter and increase and fontanel bulging.According to the position of malignant brain tumor, either via compressing or infiltration
Transfer thoroughly, is likely to directly damage tumor location and neighbouring brain structure, leads to the generation of local nerve symptom,
Such as cognition and the decline of capacity, individual character variation, hemiplegia, insensitive, aphasia, the visual field become smaller and the paralysis of face portion
Deng.
It is common for operation, chemotherapy, radiotherapy currently, treating cancer mostly uses doctor trained in Western medicine, operative treatment to the wound of human body compared with
Greatly, and operation can only control the local state of an illness, helpless for the cancer of the brain shifted;And Radiotherapy chemotherapy generation is larger
Side effect, also murdered normal cell while killing cancer cell, led to body immune hypofunction etc..And at present in
Doctor is also very not perfect to the treatment of the cancer of the brain, and drug is few, and curative effect is indefinite.
There is no one word of cancer in traditional Chinese medicine, only ulcer is said, and civil doctor is then referred to as nameless sores or boils.Carbuncle
Poison, red and swollen shoot are yang syndrome;Subcutaneous ulcer tumor, it is slow swollen gradually without shoot, for yin card.This is the penetrating and correct judgement with traditional medicine, to existing
Correct for one disease of cancer diagnoses and defines.
Carcinoma is often in swell gradually slowly, and the symptom of no shoot should belong to negative subcutaneous ulcer scope.And etiology and pathogenesis is prominent, pathology
Property is severe.Thus, should using traditional medicine sweat, spit, under and temperature, mend, clear, the temperature in the eight big therapeutic rules that disappear, benefits, clearly,
Disappear four big therapies, and need four methods develop simultaneously, synthesis treated, could ensure and disease is answered to play special efficacy to method.
This temperature refers to the scattered carcinoma of temperatureization, temperature.The cold then ice of water then coagulates, and hydro-thermal is then boiled, then changed.Carcinoma, must with high fever it
Medicine could warm dispersion solution.This benefit refers to supplement vigour, it is basic by force, realizes that righting is got rid of evils, adds the purpose for helping the efficacy of a drug.This refers to clearly
It will be cleared out of in vitro by the cancer cell of warm dispersion solution in vivo.This passway that disappears that disappears, makes medicine have route, and heresy has outlet.Only such as
This, is only real effective method for the treatment of cancer.
Summary of the invention
In order to solve the above problems existing in the present technology, the treatment high the present invention provides a kind of good effect, cure rate
Drug of the cancer of the brain and preparation method thereof.
The drug and preparation method of the treatment cancer of the brain of the present invention, it is closely related to be originated from non-material cultural heritage space-based special efficacy medical skill
" the supremo's folk prescription " passed.Through being arranged meticulously in representativeness inheritance people Li Tianji doctor more than the 50 years clinical practice of the 6th generation, constantly change
Into with promotion, obtain gratifying curative effect.
The technical scheme adopted by the invention is as follows:
A kind of drug for treating the cancer of the brain, raw material components include:
Ginseng 24-36 parts by weight, monkshood 8-12 parts by weight, Radix Salviae Miltiorrhizae 12-18 parts by weight, Rhizoma Chuanxiong 8-12 parts by weight, Radix Notoginseng
4.8-7.2 parts by weight, pueraria lobata 12-18 parts by weight, cimicifugae foetidae 8-12 parts by weight, catharanthus roseus 24-36 parts by weight, spina gleditsiae 24-36 weight
Measure part, blood clam 24-36 parts by weight, olibanum 12-18 parts by weight, root of Dahurain angelica 8-12 parts by weight, Cynanchum glaucescens 8-12 parts by weight, antelope's horn
7.2-10.8 parts by weight, agkistrodon 2-3 parts by weight, first pearl 7.2-10.8 parts by weight, centipede 3.2-4.8 parts by weight, scorpio 4.8-
7.2 parts by weight, leech 8-12 parts by weight, Eupolyphoge sinensis 8-12 parts by weight, Fructus Liquidambaris 8-12 parts by weight, Radix Glycyrrhizae 4.8-7.2 parts by weight.
The raw material components of drug of the further preferably described treatment cancer of the brain include:
30 parts by weight of ginseng, 10 parts by weight of monkshood, 15 parts by weight of Radix Salviae Miltiorrhizae, 10 parts by weight of Rhizoma Chuanxiong, 6 parts by weight of Radix Notoginseng, pueraria lobata
15 parts by weight, 10 parts by weight of cimicifugae foetidae, 30 parts by weight of catharanthus roseus, 30 parts by weight of spina gleditsiae, 30 parts by weight of blood clam, 15 weight of olibanum
Part, 10 parts by weight of the root of Dahurain angelica, 10 parts by weight of Cynanchum glaucescens, 9 parts by weight of antelope's horn, 2.5 parts by weight of agkistrodon, 9 parts by weight of first pearl, centipede 4
Parts by weight, 6 parts by weight of scorpio, 10 parts by weight of leech, 10 parts by weight of Eupolyphoge sinensis, 10 parts by weight of Fructus Liquidambaris, 6 parts by weight of Radix Glycyrrhizae.
The drug is pill or paste.
The preparation method of the pill medicine, includes the following steps:
(1) each bulk pharmaceutical chemicals component is taken, wine toast processing is carried out, obtains wine toast medicinal material;
(2) step (1) the wine toast medicinal material is subjected to pulverization process, obtains each fine drug powder;
(3) each fine drug powder be sufficiently mixed uniformly, honey is added, be made pill to get.
In step (1), the concrete operations of the wine toast processing are as follows: alcohol is added into the bulk pharmaceutical chemicals, is successively soaked
Profit, frying after letting cool, obtain wine toast medicinal material.
The mass ratio of the bulk pharmaceutical chemicals and alcohol is 1:0.15-0.25.
The time for carrying out the infiltration is 0.5-2h.
The temperature for carrying out the frying is 100-200 DEG C, and the time for carrying out the frying is 0.5-1.5h.
The preparation method of the paste medicine, includes the following steps:
(1) each raw material component is taken, is sufficiently mixed uniformly, obtains hybrid medicine;
(2) into the hybrid medicine plus water is impregnated, after decocted, filtered, obtain decoction liquor;
(3) decoction liquor is subjected to heating concentration to get paste.
In step (2), the mass ratio of hybrid medicine and addition water is 1:2-4, and the time for carrying out the immersion is 1-3h.
To facilitate the understanding of the present invention, below in the present invention raw material and drug effect be further elaborated.
Ginseng, sweet in flavor, slight bitter are mild-natured.Replenish vital energy, restore pulse, and strengthen and remove vital energy reinforces the spleen to benefit the lung, and promotes the production of body fluid, and calms the nerves.For physically weak desire
It takes off, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung is breathed with cough, and injury thirst, Heat Diabetes, prolonged illness void is thin, insomnia of palpitating with fear, impotence palace cold;The heart
Force failure, cardiogenic shock.
Monkshood, acrid flavour, sweet, extremely hot in nature;It is toxic.Recuperating depleted yang, mends fire supporing yang, by wind-cold damp pathogen.It collapses for yang depletion, limb
Cold weak pulse, impotence, palace cold, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, numbness and ache of cold dampness.
Radix Salviae Miltiorrhizae, bitter, cold nature.Stasis-dispelling and pain-killing, blood circulation, relieving restlessness and restlessness.For irregular menstruation, amenorrhea and algomenorrhea, disease
Lump in the abdomen accumulation, chest and abdomen shouting pain, hot numbness pain, sore and ulcer, swelling and pain, upset and sleepless;Hepatosplenomegaly, angina pectoris.
Rhizoma Chuanxiong, acrid flavour are warm-natured.Blood-activating and qi-promoting, wind-expelling pain-stopping.For irregular menstruation, amenorrhea and algomenorrhea, abdominal mass abdominal pain, chest side of body
Shouting pain, tumbling and swelling, headache, rheumatic arthralgia.
Radix Notoginseng, sweet in flavor, slight bitter are warm-natured.Dissipating stasis and stanching bleeding, detumescence ding-tong.For spitting blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, outside
Hurt bleeding, chest and abdomen twinge, tumbling and swelling.
Pueraria lobata, it is sweet in flavor, pungent, it is cool in nature.Expelling pathogenic factors from muscles and skin is brought down a fever, and is promoted the production of body fluid, promoting eruption, Shengyang Zhixie.For fever caused by exogenous pathogens headache, rigid neck and back
Bitterly, thirsty, it quenches one's thirst, measles without adequate eruption, hot dysentery, diarrhea;Hypertension neck pain.
Cimicifugae foetidae, acrid flavour, micro-sweet, cold nature.Promoting eruption is delivered, clearing heat and detoxicating, lifting disease.For headache due to pathogenic wind-heat, dentalgia, mouth
Sore, abscess of throat, measles without adequate eruption, sun poison macular eruption;Rectal prolapse, uterine prolapse.
Catharanthus roseus, mildly bitter flavor are cool in nature.It is toxic.Anticancer, blood pressure lowering.For acute lymphatic leukemia, lymph meat
Tumor, giant follicular lymphoma, high blood pressure.
Spina gleditsiae, acrid flavour are warm-natured.Detumescence and poison retention, apocenosis, desinsection.For ulcer from the beginning of or purulence at not bursting;Scabies fiber crops are controlled outside
Wind.
Blood clam, taste is salty, mild-natured.Removing phlegm and blood stasis, resolving hard lump, hyperacidity and pain relief.It is tied for chronic phlegm product, sticky difficulty is coughed up, goitre
Tumor, scrofula, abdominal mass lump in the abdomen, stomachache and sour regurgitation.
Olibanum, acrid flavour, hardship are warm-natured.Promoting blood circulation and stopping pain.For all pains of trusted subordinate, muscle arteries and veins contraction, traumatic injury, sore, carbuncle and painful swelling;Outside
Use detumescence and promoting granulation.
The root of Dahurain angelica, acrid flavour are warm-natured.Relieve heat dehumidifying, sensible analgesic, detumescence and apocenosis.For cold headache, pain in the supra-orbital bone is had a stuffy nose,
Nasosinusitis, toothache, leukorrhea, sore swell and ache curative.
Cynanchum glaucescens, acrid flavour, hardship, slightly warm in nature.Sending down abnormally ascending, dissolving phlegm, cough-relieving.Stop up real, coughing with a lot of sputum for lung qi, fullness sensation in chest asthma is anxious.
Antelope's horn, taste is salty, cold in nature.Suppressing hyperactive liver for calming endogenous wind clears liver and improve vision, and dissipates blood removing toxic substances.For high fever frightened epilepsy, coma convulsion is fainted, son
Epilepsy twitch, epilepsy are gone mad, headache and dizziness, cataract, febrile virulent maculae, carbuncle sore tumefacting virus.
Agkistrodon, it is sweet in flavor, salty, it is warm-natured;It is toxic.Wind-dispelling, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, middle air port
It is askew, hemiplegia, spasm of twitching, tetanus, leprosy scabies, scrofula malignant sore.
First pearl, taste is salty, cold nature.Invigorate blood circulation the Xie that disappears, newborn under promoting menstruation, and detumescence and apocenosis searches wind and removing obstruction in channels.For menostasis Xie lump in the abdomen, cream
Juice is obstructed, carbuncle sore tumefacting virus, rheumatic arthralgia, paralysis due to windstroke, numbness contracture.
Centipede, acrid flavour are warm-natured;It is toxic.Relieve the wind syndrome antispastic, function poison dissipating bind, removes obstruction in channels to relieve pain.For child convulsion, spasm of twitching,
Middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, sore, scrofula, venomous snake bite.
Scorpio, acrid flavour are mild-natured;It is toxic.Relieve the wind syndrome antispastic, dispersing pathogen accumulation are removed obstruction in channels to relieve pain.For child convulsion, spasm of twitching,
Middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.
Leech, taste is salty, bitter, mild-natured;It is slightly poisonous.Blood-breaking, by the stasis of blood, promoting menstruation.For abdominal mass lump in the abdomen, blood stasis falls and flutters damage
Wound.
Eupolyphoge sinensis, taste is salty, cold in nature;It is slightly poisonous.Broken stasis of blood blood, continuous muscles and bones.For injured bone, blood stasis closed, abdominal mass lump in the abdomen.
Fructus Liquidambaris, bitter are mild-natured.Dispelling, collateral-activating, Li Shui stimulates the menstrual flow.For arthralgia, numbness contracture, edema swelling, cream
Few menostasis.
Radix Glycyrrhizae, it is sweet in flavor, it is mild-natured.It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For taste
Weakness, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
The invention has the benefit that
The drug of the treatment cancer of the brain of the present invention, by using ginseng, monkshood, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Notoginseng, pueraria lobata, liter
Fiber crops, catharanthus roseus, spina gleditsiae, blood clam, olibanum, the root of Dahurain angelica, Cynanchum glaucescens, antelope's horn, agkistrodon, first pearl, centipede, scorpio, leech, soil
Member, Fructus Liquidambaris, 22 taste Chinese herbal medicine of Radix Glycyrrhizae are raw material and carry out appropriate weight proportion, and ginseng can reinforce vital energy in side, promote longevity
Anti-aging, modern pharmacological research prove, Central nervous and higher nervous activity have a humidification, explanation can direct uplink,
Brain is acted on, ameboid cell can also be made to tend to normally, there is antitumaous effect;It is monarch drug in a prescription that we, which reuse ginseng, commands full side, helps
Just get rid of evils;Monkshood is big medicine of a warm nature object, and mends fire supporing yang assists ginseng, and temperatureization carcinoma may be capable ministerial drug;Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, it is living
Blood promoting menstruation, Radix Salviae Miltiorrhizae surpasses Siwu Tang simply, it is seen that its function;Rhizoma Chuanxiong promoting blood circulation, promoting the circulation of qi, analgesic;Radix Notoginseng dissipates the stasis of blood, detumescence, analgesic therapy;Pueraria lobota
Root, rising Yang, expelling pathogenic factors from muscles and skin;Cimicifugae foetidae aids pueraria lobata, resultant force lifting disease uplink;Catharanthus roseus has significant antitumaous effect, to He Jiejinshi
Disease, choriocarcinoma, acute lymphatic leukaemia, malignant lymphoma, giant follicular lymphoma, hypertension etc. are curative for effect;Spina gleditsiae
Anticancer, antitoxin, detumescence, apocenosis, have inhibiting effect to sarcoma 180, and the inhibiting rate to JTC-26 is 50-70%;Blood clam stagnation resolvation,
Softening hard masses, dissipating bind;Olibanum promoting blood circulation stretches muscle, reduces swelling, having extensive analgesic activity;The root of Dahurain angelica can excited medulla oblongata respiratory center, vasomotion
Maincenter and vagus nerve, and can reduce swelling, only have a headache;Cynanchum glaucescens sending down abnormally ascending, resolving sputum;Bush promoting circulation of blood dissolving stasis, swelling and pain relieving;Antelope's horn solution
Poison, calm, anti-convulsion is relieving convulsion;Agkistrodon, first pearl relieving convulsion, promoting menstruation, active, detumescence, apocenosis;Centipede, scorpio dispersing pathogen accumulation, dredging collateral stop
Bitterly;Eupolyphoge sinensis, leech blood-breaking, by the stasis of blood, promoting menstruation, continuous muscles and bones;The medicine of Fructus Liquidambaris and a variety of Zhuo Li get through twelve channels and collaterals combined into assistant,
Drug delivery power reaches lesion, by malicious evil external out;Radix Glycyrrhizae removing toxic substances, and coordinating the drug actions of a prescription, and become making for many medicines in side.Monarch minister, helps, makes
Generous heavy medicine is played to search altogether and be picked a bone, and product of assaulting fortified position brokenly, detoxification swings cancer, and heresy is enabled to disappear positive length, the definite curative effect that disease goes people to pacify.This be by
In the more other cancers of the cancer of the brain, the maximum difficulty for the treatment of is that the efficacy of a drug is difficult to up to sick position;The head of human body is stood high above the masses, far from five
Dirty six internal organs, and rush, wantonly two arteries and veins end is between words, also without head, the efficacy of a drug of therapeutic agent is caused to be difficult to reach lesion,
And difficulty obtains curative effect;It follows that the key of the treatment cancer of the brain is priming uplink head, disease of going directly position.Data are shown: institute of the present invention
Drug is stated for treating 81% or more the effective percentage of the cancer of the brain, obvious effective rate 69%, cure rate 63%, good effect, cure rate height.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below
Detailed description.Obviously, the described embodiment is only a part of the embodiment of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art without making creative work it is obtained it is all its
Its embodiment belongs to the range that the present invention is protected.
1g is represented in following embodiment with 1 parts by weight.
Embodiment 1
The present embodiment provides a kind of pill for treating the cancer of the brain, raw material components include:
24 parts by weight of ginseng, 12 parts by weight of monkshood, 12 parts by weight of Radix Salviae Miltiorrhizae, 12 parts by weight of Rhizoma Chuanxiong, 4.8 parts by weight of Radix Notoginseng, Pueraria lobota
18 parts by weight of root, 8 parts by weight of cimicifugae foetidae, 36 parts by weight of catharanthus roseus, 24 parts by weight of spina gleditsiae, 36 parts by weight of blood clam, 12 weight of olibanum
Measure part, 12 parts by weight of the root of Dahurain angelica, 8 parts by weight of Cynanchum glaucescens, 10.8 parts by weight of antelope's horn, 2 parts by weight of agkistrodon, 10.8 parts by weight of first pearl,
3.2 parts by weight of centipede, 7.2 parts by weight of scorpio, 8 parts by weight of leech, 12 parts by weight of Eupolyphoge sinensis, 8 parts by weight of Fructus Liquidambaris, 7.2 weight of Radix Glycyrrhizae
Measure part.
Further, the present embodiment provides the preparation method of the pill of the treatment cancer of the brain, include the following steps:
(1) each bulk pharmaceutical chemicals component is taken, it is as follows to carry out wine toast processing respectively: being added into bulk pharmaceutical chemicals and accounts for 15% mass of bulk pharmaceutical chemicals
Alcohol, first carry out infiltration 0.5h, then in 100 DEG C of frying 1.5h, after letting cool, obtain wine toast medicinal material;
(2) step (1) the wine toast medicinal material is subjected to pulverization process, obtains each fine drug powder;
(3) each fine drug powder be sufficiently mixed uniformly, rape flower honey is added, the thin ball of 0.2g/ ball is made, as
The pill of the treatment cancer of the brain.
Embodiment 2
The present embodiment provides a kind of pill for treating the cancer of the brain, raw material components include:
36 parts by weight of ginseng, 8 parts by weight of monkshood, 18 parts by weight of Radix Salviae Miltiorrhizae, 8 parts by weight of Rhizoma Chuanxiong, 7.2 parts by weight of Radix Notoginseng, pueraria lobata
12 parts by weight, 12 parts by weight of cimicifugae foetidae, 24 parts by weight of catharanthus roseus, 36 parts by weight of spina gleditsiae, 24 parts by weight of blood clam, 18 weight of olibanum
Part, 8 parts by weight of the root of Dahurain angelica, 12 parts by weight of Cynanchum glaucescens, 7.2 parts by weight of antelope's horn, 3 parts by weight of agkistrodon, 7.2 parts by weight of first pearl, centipede
4.8 parts by weight, 4.8 parts by weight of scorpio, 12 parts by weight of leech, 8 parts by weight of Eupolyphoge sinensis, 12 parts by weight of Fructus Liquidambaris, 4.8 weight of Radix Glycyrrhizae
Part.
Further, the present embodiment provides the preparation method of the pill of the treatment cancer of the brain, include the following steps:
(1) each bulk pharmaceutical chemicals component is taken, it is as follows to carry out wine toast processing respectively: being added into bulk pharmaceutical chemicals and accounts for 25% mass of bulk pharmaceutical chemicals
Alcohol, first carry out infiltration 2h, then in 200 DEG C of frying 0.5h, after letting cool, obtain wine toast medicinal material;
(2) step (1) the wine toast medicinal material is subjected to pulverization process, obtains each fine drug powder;
(3) each fine drug powder be sufficiently mixed uniformly, rape flower honey is added, the thin ball of 0.2g/ ball is made, as
The pill of the treatment cancer of the brain.
Embodiment 3
The present embodiment provides a kind of pill for treating the cancer of the brain, raw material components include:
30 parts by weight of ginseng, 10 parts by weight of monkshood, 15 parts by weight of Radix Salviae Miltiorrhizae, 10 parts by weight of Rhizoma Chuanxiong, 6 parts by weight of Radix Notoginseng, pueraria lobata
15 parts by weight, 10 parts by weight of cimicifugae foetidae, 30 parts by weight of catharanthus roseus, 30 parts by weight of spina gleditsiae, 30 parts by weight of blood clam, 15 weight of olibanum
Part, 10 parts by weight of the root of Dahurain angelica, 10 parts by weight of Cynanchum glaucescens, 9 parts by weight of antelope's horn, 2.5 parts by weight of agkistrodon, 9 parts by weight of first pearl, centipede 4
Parts by weight, 6 parts by weight of scorpio, 10 parts by weight of leech, 10 parts by weight of Eupolyphoge sinensis, 10 parts by weight of Fructus Liquidambaris, 6 parts by weight of Radix Glycyrrhizae.
Further, the present embodiment provides the preparation method of the pill of the treatment cancer of the brain, include the following steps:
(1) each bulk pharmaceutical chemicals component is taken, it is as follows to carry out wine toast processing respectively: being added into bulk pharmaceutical chemicals and accounts for 20% mass of bulk pharmaceutical chemicals
Alcohol, first carry out infiltration 1.2h, then in 150 DEG C of frying 1h, after letting cool, obtain wine toast medicinal material;
(2) step (1) the wine toast medicinal material is subjected to pulverization process, obtains each fine drug powder;
(3) each fine drug powder be sufficiently mixed uniformly, rape flower honey is added, the thin ball of 0.2g/ ball is made, as
The pill of the treatment cancer of the brain.
The instructions of taking of pill described in embodiment 1-3: adult each 9-12g takes medicine on an empty stomach sooner or later 2 times a day, takes medicine
It is fed again after 60-90min.Children's dosage halves.
Points for attention: 1, can not sexual intercourse during treating.2, medication cannot be interrupted.3, fasting white sugar, green onion, ginger, garlic etc.
The food of the anti-pharmacological property such as maror and white radishes, mung bean.It 4, should not be with other drugs with clothes.
Embodiment 4
The present embodiment provides a kind of paste for treating the cancer of the brain, raw material components include:
24 parts by weight of ginseng, 12 parts by weight of monkshood, 12 parts by weight of Radix Salviae Miltiorrhizae, 12 parts by weight of Rhizoma Chuanxiong, 4.8 parts by weight of Radix Notoginseng, Pueraria lobota
18 parts by weight of root, 8 parts by weight of cimicifugae foetidae, 36 parts by weight of catharanthus roseus, 24 parts by weight of spina gleditsiae, 36 parts by weight of blood clam, 12 weight of olibanum
Measure part, 12 parts by weight of the root of Dahurain angelica, 8 parts by weight of Cynanchum glaucescens, 10.8 parts by weight of antelope's horn, 2 parts by weight of agkistrodon, 10.8 parts by weight of first pearl,
3.2 parts by weight of centipede, 7.2 parts by weight of scorpio, 8 parts by weight of leech, 12 parts by weight of Eupolyphoge sinensis, 8 parts by weight of Fructus Liquidambaris, 7.2 weight of Radix Glycyrrhizae
Measure part.
Further, the present embodiment provides the preparation method of the paste of the treatment cancer of the brain, include the following steps:
(1) each raw material component is taken, is sufficiently mixed uniformly, obtains hybrid medicine;
(2) it into the hybrid medicine plus 2 times of quality water carry out immersion 3h, is first fried boiling 5min with high fire later, then with small
Fire decocts 90min, and filtering obtains decoction liquor;
(3) decoction liquor is carried out to heating at 40 DEG C and is concentrated into the 2/3 of original volume to get the cream of the treatment cancer of the brain
Agent.
Embodiment 5
The present embodiment provides a kind of paste for treating the cancer of the brain, raw material components include:
36 parts by weight of ginseng, 8 parts by weight of monkshood, 18 parts by weight of Radix Salviae Miltiorrhizae, 8 parts by weight of Rhizoma Chuanxiong, 7.2 parts by weight of Radix Notoginseng, pueraria lobata
12 parts by weight, 12 parts by weight of cimicifugae foetidae, 24 parts by weight of catharanthus roseus, 36 parts by weight of spina gleditsiae, 24 parts by weight of blood clam, 18 weight of olibanum
Part, 8 parts by weight of the root of Dahurain angelica, 12 parts by weight of Cynanchum glaucescens, 7.2 parts by weight of antelope's horn, 3 parts by weight of agkistrodon, 7.2 parts by weight of first pearl, centipede
4.8 parts by weight, 4.8 parts by weight of scorpio, 12 parts by weight of leech, 8 parts by weight of Eupolyphoge sinensis, 12 parts by weight of Fructus Liquidambaris, 4.8 weight of Radix Glycyrrhizae
Part.
Further, the present embodiment provides the preparation method of the paste of the treatment cancer of the brain, include the following steps:
(1) each raw material component is taken, is sufficiently mixed uniformly, obtains hybrid medicine;
(2) it into the hybrid medicine plus 4 times of quality water carry out immersion 1h, is first fried boiling 5min with high fire later, then with small
Fire decocts 90min, and filtering obtains decoction liquor;
(3) decoction liquor is carried out to heating at 50 DEG C and is concentrated into the 2/3 of original volume to get the cream of the treatment cancer of the brain
Agent.
Embodiment 6
The present embodiment provides a kind of paste for treating the cancer of the brain, raw material components include:
30 parts by weight of ginseng, 10 parts by weight of monkshood, 15 parts by weight of Radix Salviae Miltiorrhizae, 10 parts by weight of Rhizoma Chuanxiong, 6 parts by weight of Radix Notoginseng, pueraria lobata
15 parts by weight, 10 parts by weight of cimicifugae foetidae, 30 parts by weight of catharanthus roseus, 30 parts by weight of spina gleditsiae, 30 parts by weight of blood clam, 15 weight of olibanum
Part, 10 parts by weight of the root of Dahurain angelica, 10 parts by weight of Cynanchum glaucescens, 9 parts by weight of antelope's horn, 2.5 parts by weight of agkistrodon, 9 parts by weight of first pearl, centipede 4
Parts by weight, 6 parts by weight of scorpio, 10 parts by weight of leech, 10 parts by weight of Eupolyphoge sinensis, 10 parts by weight of Fructus Liquidambaris, 6 parts by weight of Radix Glycyrrhizae.
Further, the present embodiment provides the preparation method of the paste of the treatment cancer of the brain, include the following steps:
(1) each raw material component is taken, is sufficiently mixed uniformly, obtains hybrid medicine;
(2) it into the hybrid medicine plus 3 times of quality water carry out immersion 2h, is first fried boiling 5min with high fire later, then with small
Fire decocts 90min, and filtering obtains decoction liquor;
(3) decoction liquor is carried out to heating at 45 DEG C and is concentrated into the 2/3 of original volume to get the cream of the treatment cancer of the brain
Agent.
The instructions of taking of paste medicine described in embodiment 4-5: 2 times a day, each 120-150ml, the morning and evening is on an empty stomach by adult
Medication, medication are fed again after 60-90 minutes.Children's dosage halves.
Points for attention: 1, can not sexual intercourse during treating.2, medication cannot be interrupted.3, fasting white sugar, green onion, ginger, garlic etc.
The food of the anti-pharmacological property such as maror and white radishes, mung bean.It 4, should not be with other drugs with clothes.
Experimental example
The present inventor is by taking the observation of drug of the present invention to clinical 239 cancer of the brain patients, wherein effective 193
People, effective 165 people, effective middle 150 people of clinical cure.
Application method: it is taken according to the above-mentioned instructions of taking of pill or paste.
Efficacy assessment standard:
It is effective: compare the treatment condition before treating or carried out early period, feels symptom and alleviated, life quality
It makes moderate progress.
Effective: more similar patient, clinical manifestation pathology period are elongated, and life quality is obviously improved, 1 year life cycle with
On.
Clinical cure: various kinds physical examination index is normal, and life cycle 5 years or more.
It is specific as shown in table 1.
The therapeutic effect of table 1- drug of the present invention counts
Therapeutic effect | Effectively | It is effective | Clinical cure |
Number | 193 | 165 | 150 |
Percentage | 81% | 69% | 63% |
As it can be seen from table 1 drug of the present invention is used to treat 81% or more the effective percentage of the cancer of the brain, obvious effective rate 69%,
Cure rate 63%, good effect, cure rate are high.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of drug for treating the cancer of the brain, which is characterized in that raw material components include:
Ginseng 24-36 parts by weight, monkshood 8-12 parts by weight, Radix Salviae Miltiorrhizae 12-18 parts by weight, Rhizoma Chuanxiong 8-12 parts by weight, Radix Notoginseng 4.8-7.2
Parts by weight, pueraria lobata 12-18 parts by weight, cimicifugae foetidae 8-12 parts by weight, catharanthus roseus 24-36 parts by weight, spina gleditsiae 24-36 parts by weight, watt
Stupefied sub- 24-36 parts by weight, olibanum 12-18 parts by weight, root of Dahurain angelica 8-12 parts by weight, Cynanchum glaucescens 8-12 parts by weight, antelope's horn 7.2-10.8
Parts by weight, agkistrodon 2-3 parts by weight, first pearl 7.2-10.8 parts by weight, centipede 3.2-4.8 parts by weight, scorpio 4.8-7.2 weight
Part, leech 8-12 parts by weight, Eupolyphoge sinensis 8-12 parts by weight, Fructus Liquidambaris 8-12 parts by weight, Radix Glycyrrhizae 4.8-7.2 parts by weight.
2. the drug of the treatment cancer of the brain according to claim 1, which is characterized in that raw material components include:
30 parts by weight of ginseng, 10 parts by weight of monkshood, 15 parts by weight of Radix Salviae Miltiorrhizae, 10 parts by weight of Rhizoma Chuanxiong, 6 parts by weight of Radix Notoginseng, 15 weight of pueraria lobata
Measure part, 10 parts by weight of cimicifugae foetidae, 30 parts by weight of catharanthus roseus, 30 parts by weight of spina gleditsiae, 30 parts by weight of blood clam, 15 parts by weight of olibanum,
10 parts by weight of the root of Dahurain angelica, 10 parts by weight of Cynanchum glaucescens, 9 parts by weight of antelope's horn, 2.5 parts by weight of agkistrodon, 9 parts by weight of first pearl, 4 weight of centipede
Part, 6 parts by weight of scorpio, 10 parts by weight of leech, 10 parts by weight of Eupolyphoge sinensis, 10 parts by weight of Fructus Liquidambaris, 6 parts by weight of Radix Glycyrrhizae.
3. the drug of the treatment cancer of the brain according to claim 1, which is characterized in that the drug is pill or paste.
4. the preparation method of pill medicine as claimed in claim 3, which comprises the steps of:
(1) each bulk pharmaceutical chemicals component is taken, wine toast processing is carried out, obtains wine toast medicinal material;
(2) step (1) the wine toast medicinal material is subjected to pulverization process, obtains each fine drug powder;
(3) each fine drug powder be sufficiently mixed uniformly, honey is added, be made pill to get.
5. the preparation method of pill medicine according to claim 4, which is characterized in that in step (1), the wine toast processing
Concrete operations are as follows: alcohol is added into the bulk pharmaceutical chemicals, successively infiltrated, frying, let cool after, obtain wine toast medicinal material.
6. the preparation method of pill medicine according to claim 5, which is characterized in that the quality of the bulk pharmaceutical chemicals and alcohol
The ratio between be 1:0.15-0.25.
7. the preparation method of pill medicine according to claim 5, which is characterized in that the time for carrying out the infiltration is
0.5-2h。
8. the preparation method of pill medicine according to claim 5, which is characterized in that the temperature for carrying out the frying is
100-200 DEG C, the time for carrying out the frying is 0.5-1.5h.
9. the preparation method of paste medicine according to claim 3, which comprises the steps of:
(1) each raw material component is taken, is sufficiently mixed uniformly, obtains hybrid medicine;
(2) into the hybrid medicine plus water is impregnated, after decocted, filtered, obtain decoction liquor;
(3) decoction liquor is subjected to heating concentration to get paste.
10. preparation method according to claim 9, which is characterized in that in step (2), the matter of hybrid medicine and addition water
The ratio between amount is 1:2-4, and the time for carrying out the immersion is 1-3h.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811430347.4A CN109288899A (en) | 2018-11-27 | 2018-11-27 | A kind of drug and preparation method thereof for treating the cancer of the brain |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811430347.4A CN109288899A (en) | 2018-11-27 | 2018-11-27 | A kind of drug and preparation method thereof for treating the cancer of the brain |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109288899A true CN109288899A (en) | 2019-02-01 |
Family
ID=65144925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201811430347.4A Pending CN109288899A (en) | 2018-11-27 | 2018-11-27 | A kind of drug and preparation method thereof for treating the cancer of the brain |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109288899A (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1327807A (en) * | 2000-06-12 | 2001-12-26 | 吴建华 | Chinese medicine for treating neoplasm |
CN101721664A (en) * | 2008-11-04 | 2010-06-09 | 王生 | Traditional Chinese medicine for treating apoplectic hemiplegia and general paralysis |
-
2018
- 2018-11-27 CN CN201811430347.4A patent/CN109288899A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1327807A (en) * | 2000-06-12 | 2001-12-26 | 吴建华 | Chinese medicine for treating neoplasm |
CN101721664A (en) * | 2008-11-04 | 2010-06-09 | 王生 | Traditional Chinese medicine for treating apoplectic hemiplegia and general paralysis |
Non-Patent Citations (2)
Title |
---|
李仲愚: "《医道家课》", 31 January 2009, 四川科学技术出版社 * |
杨建宇等: "《一本书读懂中草药抗癌》", 31 August 2014, 中原农民出版社 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103736072B (en) | Medicine of a kind for the treatment of of allergic rhinitis and preparation method thereof | |
CN107397934A (en) | A kind of body-building kidney-reinforcing medicinal liquor | |
CN105663656A (en) | Pharmaceutical composition for treating sleep disorders and preparing method thereof | |
CN108144010A (en) | A kind of Chinese medicine composition and preparation method for treating cardiovascular and cerebrovascular disease | |
CN107397939A (en) | One kind is used to treat neurasthenic Chinese medicine preparation | |
CN102335356A (en) | Oral Chinese patent medicine for treating epilepsy | |
CN105535495A (en) | Chinese medicinal composition for treating esophageal cancer by reinforcing vital essence and strengthening primordial qi and preparation method | |
CN104258369A (en) | Traditional Chinese medicine composition for treating epigastric pain | |
CN109288899A (en) | A kind of drug and preparation method thereof for treating the cancer of the brain | |
CN104971204A (en) | Kidney-tonifying and resuscitation-inducing pill and medicinal strip cooperating with acupuncture for treating neurological tinnitus | |
CN105012732B (en) | Traditional Chinese medicine pill for treating sleep disorder syndrome and preparation method thereof | |
CN103861075A (en) | Traditional Chinese medicine for treating insomnia and preparation method thereof | |
CN104688855B (en) | A kind of Chinese goldthread colla corii asini composition for treating chronic fatigue syndrome and its application | |
CN107095985A (en) | A kind of instant particles as Chinese medicine and preparation method for being used to treat that postpartum insomnia is levied | |
CN107929644A (en) | A kind of Chinese medicine composition for treating sinus bradycardia and preparation method thereof | |
CN103877216B (en) | One treats myocarditic Chinese drugs agentia and preparation method | |
CN103479953B (en) | The preparation method of digestion-promoting spleen-invigorating medicine | |
CN103830649B (en) | A kind of medicine for the treatment of chronic alcoholism and preparation method thereof | |
CN108126117A (en) | A kind of Chinese medicine composition for treating cerebral infarction | |
CN105287982A (en) | Traditional Chinese medicine oral liquid for treating epilepsy and preparation method for traditional Chinese medicine oral liquid | |
CN105920574A (en) | Palpitation treatment medicine and preparation method thereof | |
CN105125786A (en) | Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and preparation method thereof | |
CN105596697A (en) | Traditional Chinese medicine electuary for treating tourette syndrome of children and preparation method | |
CN104784588A (en) | Traditional Chinese medicine preparation for treating nerve headache and preparation method | |
CN103735841A (en) | Drug for treating cold and cough and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190201 |