CN109260138A - A kind of Shu Min repairs spraying and its production method - Google Patents
A kind of Shu Min repairs spraying and its production method Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
A kind of Shu Min repairs spraying and its production method, is related to cosmetic technical field, which repairs the parts by weight of spraying component and each component are as follows: A:0.01-5 parts of component, B:0.05-4 parts of component, component C: 0.1-15 parts, glycyrrhetate: 0.05-4 parts, water: 80-100 parts.Spraying production method is repaired the present invention also provides a kind of Shu Min, this method simple process, it is easy to produce to operate, is at low cost, to equipment without particular/special requirement, comprehensive anti-inflammatory, sensitive skin of releiving, enhancing skin resistance may be implemented in the Shu Min reparation produced by spraying, and finally realizes the radical cure to sensitive skin, and effect is obviously quick, it is without side-effects to body, it will not lower the resistance of the body.
Description
Technical field:
The present invention relates to cosmetic technical fields, and in particular to a kind of Shu Min repairs spraying and its production method.
Background technique:
Skin is the outmost one layer of structure of human body, it makes various in vivo organize with organ from physical, mechanicalness, change
The invasion the first line of defence of the property learned and pathogenic microorganism.When the natural barrier of skin is complete, moisture is not easily runed off in skin,
And skin is not easy to be invaded by foreign substances such as bacteriums, protection skin is without damage.But after skin damage, moisture of skin percutaneously flows
It loses and increases, water holding capacity is poor, and skin is easily dry, while being deteriorated to the resilience of environmental stimuli, will when by external irritant
The malaise symptoms such as shouting pain, redness, itch are generated, the sensitivity of skin is caused.
The increase of life stress, stay up late, extraneous stimulation, cosmetics a large amount of reasons such as be used for a long time result in skin day
It is beneficial sensitive, allergic phenomena is generated to stimulations such as extraneous environment, pollen, dusts, thus there are the discomforts such as redness, itch, shouting pain,
It is needed when allergic phenomena occurs in skin using antianaphylactic drug or Shu Min spraying, phenomena of cutaneous irritation is eliminated with this.
Existing antianaphylactic drug and Shu Min are to realize antiallergy using human allergy's immune response is inhibited by spraying, still, existing
Some Claritins and Shu Min, which are sprayed at, inhibits that the immune response of human normal can be inhibited when allergic immune response simultaneously, when connecing
When contacting germ or bacterium, human body can not generate normal immune response, cause resistance of human body low, the tolerance of skin and
Resistance decreases, and weakens significantly so as to cause resistance of the human body to extraneous germ or bacterium, causes skin to occur scorching
The generation of phenomena such as disease, melanin deposition, skin tinea.In addition, containing hormone, meeting during existing Claritin and Shu Min are spraying
The disorder for leading to inside of human body hormone brings bigger influence to the body of people.
Summary of the invention:
In place of overcoming above-mentioned the shortcomings of the prior art, and provide a kind of Shu Min reparation spray
Mist, which repairs is acted synergistically by Multicomponent by spraying, anti-inflammatory, sensitive, reparation skin of releiving comprehensively may be implemented, from root
Existing skin injury and allergic phenomena are solved on source.
Spraying production method is repaired it is a further object to provide a kind of Shu Min, the production method technique letter
Single, operation easy to produce, for production method to relying property of device independence, production cost is low, production process environment-protecting clean.
The technical solution adopted by the present invention are as follows: a kind of Shu Min reparation is spraying, which repairs spraying component and each component
Parts by weight are as follows: A:0.01-5 parts of component, B:0.05-4 parts of component, component C: 0.1-15 parts, glycyrrhetate: 0.05-4 parts,
Water: 80-100 parts.
Preferably, which repairs the parts by weight of spraying component and each component are as follows: and A:0.1-2 parts of component, component B:
0.1-1 parts, component C: 1-10 parts, glycyrrhetate: 0.1-1 parts, water: 85-99 parts.
Preferably, the component A be chitosan oligosaccharide, carboxymethylchitosan, chitinous oligomers, carboxymethyl chitosan,
Any one in chitin or any two kinds or any two or more mixture.
Preferably, the component B is selected from one or both of plankton extractions, peony root extractive.
Preferably, the component C appointing in wormwood hydrosol, lavender hydrosol, chamomile hydrosol, balm hydrosol
One kind of anticipating or any two kinds or any two or more mixture.
Preferably, the Shu Min repairs the preservative containing 0.01-3 parts by spraying.
Preferably, the glycyrrhetate is ammonium glycyrrhizinate, glycyrrhizic acid list potassium, diammonium glycyrrhizinate, dipotassium glycyrrhizinate, Radix Glycyrrhizae
Any one in sour dipotassium, disodium glycyrrhizinate or any two kinds or any two or more mixture.
A kind of Shu Min repairs spraying production method, method includes the following steps:
Step A: water being added into reaction vessel, and component A is added into water, heats and is stirred, at this point, heating temperature
It is 75-85 DEG C, mixing speed 50-80rpm/min obtains preliminary mixed liquor；
Step B: carrying out vacuum homogeneous for preliminary mixed liquor obtained in step A and be stirred, incorporation time 1-
15min, at this point, vacuum degree is -0.03MPa to -0.04MPa, mixing speed 2000-4000rpm/min, the mixing of vacuum homogeneous
Constant temperature stands 15-30min afterwards, obtains standing liquid；
Step C: the temperature of the standing liquid in step B is down to 40-50 DEG C, sequentially adds component B, component C and glycyrrhizic acid
Salt is stirred, mixing speed 30-40rpm/min；
Step D: the pH value of mixed liquor obtained in detecting step C, it is qualified when pH value is 3.5-5.5 and discharge, by raw material
Filtering, obtains filtrate, and product is made.
The invention has the benefit that the Shu Min in the present invention repairs the spraying mechanism according to skin allergic reaction, pass through
It mutually acts synergistically between each component, realizes anti-inflammatory, sensitive skin of releiving, enhancing skin resistance, and finally realization pair comprehensively
The radical cure of sensitive skin, effect is obviously quick, without side-effects to body, will not lower the resistance of the body, in addition, the Shu Minxiu
It is spraying hormone-free again, more there is repairing effect to impaired skin, promotes the abatement of scytitis and the healing of wound.In the present invention
Shu Min to repair spraying preparation process simple, it is operation easy to produce, at low cost, to equipment without particular/special requirement.
Detailed description of the invention:
Fig. 1 is the suppression inflammation mechanism figure in the present invention.
Specific embodiment:
Invention is further explained in conjunction with specific embodiments:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: component A:0.01-
5 parts, B:0.05-4 parts of component, component C: 0.1-15 parts, glycyrrhetate: 0.05-4 parts, water: 80-100 parts.
The Shu Min repairs the parts by weight of spraying component and each component are as follows: and A:0.1-2 parts of component, B:0.1-1 parts of component,
Component C: 1-10 parts, glycyrrhetate: 0.1-1 parts, water: 85-99 parts.
The component A is chitosan oligosaccharide, in carboxymethylchitosan, chitinous oligomers, carboxymethyl chitosan, chitin
Any one or any two kinds or any two or more mixture.
The component B is selected from one or both of plankton extractions, peony root extractive.
Any one of the component C in wormwood hydrosol, lavender hydrosol, chamomile hydrosol, balm hydrosol
Or any two kinds or any two or more mixture.
The Shu Min repairs the preservative containing 0.01-3 parts by spraying.Preservative be antibacterial peptide, clove leaf stem cell liquid,
Vanillic aldehyde, chitosan, dehydroacetic acid, Herba Lysimachiae foenumgraeci extract, in phoenix-tail fern extracting solution any one or it is two kinds or any any
Two or more mixtures.
The glycyrrhetate be ammonium glycyrrhizinate, glycyrrhizic acid list potassium, diammonium glycyrrhizinate, dipotassium glycyrrhizinate, dipotassium glycyrrhizinate,
Any one in disodium glycyrrhizinate or any two kinds or any two or more mixture.
A kind of Shu Min repairs spraying production method, method includes the following steps:
Step A: water being added into reaction vessel, and component A is added into water, heats and is stirred, at this point, heating temperature
It is 75-85 DEG C, mixing speed 50-80rpm/min obtains preliminary mixed liquor；
Step B: carrying out vacuum homogeneous for preliminary mixed liquor obtained in step A and be stirred, incorporation time 1-
15min, at this point, vacuum degree is -0.03MPa to -0.04MPa, mixing speed 2000-4000rpm/min, the mixing of vacuum homogeneous
Constant temperature stands 15-30min afterwards, obtains standing liquid；
Step C: the temperature of the standing liquid in step B is down to 40-50 DEG C, sequentially adds component B, component C and glycyrrhizic acid
Salt is stirred, mixing speed 30-40rpm/min；
Step D: the pH value of mixed liquor obtained in detecting step C, it is qualified when pH value is 3.5-5.5 and discharge, by raw material
Filtering, obtains filtrate, and product is made.
Embodiment one:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: and 1 part of chitosan oligosaccharide,
1 part of carboxymethylchitosan, 0.05 part of plankton extractions, 2 parts of peony root extractive, 1 part of lavender hydrosol, ocean is sweet
5 parts of chrysanthemum hydrosol, 3 parts of balm hydrosol, 0.1 part of ammonium glycyrrhizinate, 2 parts of dipotassium glycyrrhizinate, 100 parts of water.
Embodiment two:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: chitinous oligomers 1
Part, 2 parts of carboxymethyl chitosan, 2 parts of chitin, 3 parts of plankton extractions, 0.05 part of peony root extractive, wormwood hydrosol 0.1
Part, 10 parts of lavender hydrosol, 3 parts of chamomile hydrosol, 1 part of glycyrrhizic acid list potassium, 1 part of diammonium glycyrrhizinate, dipotassium glycyrrhizinate 2, water 80
Part.
Embodiment three:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: deionized water 86
Part, 0.05 part of chitosan oligosaccharide, 0.1 part of plankton extractions, 1.0 parts of dipotassium glycyrrhizinate, 1.0 parts of wormwood hydrosol.
Example IV:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: deionized water:
100 parts, 1 part of carboxymethylchitosan, 1 part of peony root extractive, 0.1 part of diammonium glycyrrhizinate, 5 parts of lavender hydrosol, prevent
1 part of rotten agent.
Embodiment five:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: deionized water 90
Part, 0.5 part of carboxymethyl chitosan, 0.1-2 parts of plankton extractions, 1 part of disodium glycyrrhizinate, 10 parts of chamomile hydrosol, anti-corrosion
3 parts of agent.
Implement six:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: and 1 part of chitosan oligosaccharide,
1 part of carboxymethylchitosan, 0.5 part of chitinous oligomers, 0.1 part of carboxymethyl chitosan, 1 part of chitin, planktonic organism is extracted
0.05 part of object, 15 parts of lavender hydrosol, 0.05 part of ammonium glycyrrhizinate, 1 part of glycyrrhizic acid list potassium, 0.5 part of diammonium glycyrrhizinate, glycyrrhizic acid
1.5 parts of potassium, 0.7 part of dipotassium glycyrrhizinate, 0.05 part of disodium glycyrrhizinate, 88 parts of water.
Embodiment seven:
A kind of Shu Min reparation is spraying, which repairs the parts by weight of spraying component and each component are as follows: chitosan oligosaccharide 0.01
Part, 2 parts of plankton extractions, 0.05 part of peony root extractive, 15 parts of wormwood hydrosol, 2 parts of dipotassium glycyrrhizinate, disodium glycyrrhizinate
1 part, 95 parts of water.
It is mainly to have an impact to the generation and secretion of inflammatory mediator that Shu Min in the present invention, which is repaired spraying, to inflammatory cell
Synthesis secrete cytokines have dual regulation, can significantly inhibit the people for being had induction by lipopolysaccharides (LPS) or being induced without LPS
MF discharges inflammatory cytokine, has the function of stablizing lysosome, anti-lipid peroxidation reaction and reduces TNF release.Inflammatory
Medium includes cell factor and chemotactic factor (CF), they and inflammatory cell interaction constitute the main component of inflammatory reaction, wherein
Tumor necrosis factor (TNF), interleukin 1 (IL-1) etc. play main function in inflammatory reaction, and referred to as proinflammatory reaction is situated between
Matter, the Shu Min in the present invention, which is repaired, spraying can inhibit with inflammatory cell interaction and largely the production of intracellular TNF, IL-1
It is raw, to realize the stronger effect for inhibiting inflammation.Specific mechanism such as Fig. 1 for inhibiting inflammation.
The mechanism of skin generation allergy are as follows:
(1) exogenous stimulation causes cutaneous nerve tip release Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 (SP)；
(2) SP activates NK1 receptor；
(3) NK1 receptor for stimulating mast cell；
(4) histamine release of mast cell；
(5) histamine causes gargalesthesia in conjunction with H1 histamine receptor.
Shu Min in the present invention repairs the allergy mechanism for being based primarily upon skin by spraying, carries out to spraying ingredient and content
Selected and allotment makes various composition collaboration play a role, to make the effect of every kind of ingredient maximize, to realize to dermatitis
Disease and allergic reaction are inhibited and are improved reparation, and final realize cures anaphylaxis dermatosis.Component B in the present invention is applied
The barrier function that skin can be enhanced in cosmetics, by adjust reduce pro-inflammatory interleukins IL-1 and IL-8 synthesis and
Secretion, from root at the generation for inhibiting inflammation, and the product of non-hormone is by inhibiting the allergic immune response of skin to carry out reality
It now acts on, reduces the entire immune function of body.In addition, plankton extractions are a kind of unique microalgae groups
It falls, extract, which is applied, has protection and repair well to skin in cosmetics, matches with other compositions, inhibits
The effect of inflammation enhances.
Glycyrrhetate has removing toxic substances, anti-inflammatory, analgesia, antineoplastic action, is mast cell stabilizers, acts on skin change
The four steps of state reaction reduces the ability of the stimulated rear release histamine of mast cell, so that skin be avoided itch and mistake occur
Quick reaction.
Ingredient in component A mainly acts on the 5th step of skin allergic reaction, competing with H1 histamine receptor high-affinity
Striving property, which combines, prevents histamine in conjunction with the H1 receptor for causing gargalesthesia, to achieve the effect that Quick itch stopping；
Have in the present invention refrigerant antipruritic in component C, anti-inflammatory is antibacterial, calm releives and other effects.
When various composition in the present invention is used alone, the antiallergic of every kind of ingredient, which is releived, to be had a single function, and is worked slow, effect one
As, it applies and is difficult to play good Shu Min repairing effect on cosmetics.The present invention further investigate skin allergic reaction mechanism and
Skin inhibits inflammatory mechanisms, and by the selected of ingredient and allotment, after the above raw material is compounded with scientific and reasonable ratio, collaboration increases
Effect, comprehensive antiallergic anti-inflammatory, reparation of releiving, excellent.
Using effect experiment:
(1) anti-inflammatory experiment:
Dexamethasone tablet, indication are Aeroseb-Dex, are primarily adapted for use in anaphylaxis and autoimmune is scorching
Disease property disease, such as connective tissue disease, serious bronchial asthma, the anaphylactias such as dermatitis, ulcerative colitis, acute white blood
Disease, malignant lymphoma etc..Dexamethasone tablet is a kind of hormone medicine, interior to contain hormone medicine ingredient, is a kind for the treatment of
Property drug, hormone medicine ingredient be cosmetics disabling ingredient.
The present invention carries out cell experiment using the Shu Min reparation prepared in dexamethasone tablet and the present invention by spraying, for comparing
Dexamethasone tablet and Shu Min repair the spraying inhibiting effect to inflammatory factor.Specific experiment method are as follows:
The processing training of spraying and dexamethasone tablet is repaired using the Shu Min in the present invention of the effective component containing same dose
Feeding cell, and the percentage of inflammatory factor in cell (IL-6, TNF) decline is measured, specific test result such as table one:
Table one: Shu Min repairs spraying and dexamethasone tablet cell experiment result.
| Inflammatory factor declines percentage % | IL-6 | TNF |
| Shu Min repairs spraying | 34.90% | 32.78% |
| Dexamethasone tablet 0.010% | 24.60% | 43.39% |
By above-mentioned test data of experiment, it can be concluded that, the Shu Min in the present invention repairs the synthesis and production for being sprayed at and inhibiting LF-6
Raw aspect has effects that better than hormone medicine dexamethasone tablet.In addition, the Shu Min reparation in the present invention is sprayed at and inhibits TNF
Although generation in terms of than dexamethasone tablet the effect of it is poor, effect reaches the 75% of dexamethasone tablet, and same drug is only capable of
Reach 55% or so of dexamethasone tablet.
(2) mice auricle swelling is tested:
Butyric acid hydrocortisone, the product are white or almost white crystalline powder；It is odorless.Skin disease medication is applicable in
In eczema, dermatitis, anaphylaxis dermatosis.Usage and dosage is uniformly to be applied to affected part, coating 1 time again after gently rubbing 1 minute, 2 times a day.
Butyric acid hydrocortisone is a kind of anti-inflammatory product containing hormone, although the anti-inflammatory product has good effect in treatment inflammation,
But since hormone is medicinal ingredient, it is disabling ingredient in cosmetic industry, but cosmetic industry can not be suitable for.This experiment is adopted
Spraying and butyric acid hydrocortisone is repaired to judge to compare this production with the Shu Min applied to cosmetics prepared by plant with the present invention
The anti-inflammatory effects of product, specific experiment method are as follows:
Experiment mice 90 are taken, half male and half female is randomly divided into three groups, every group 30, is respectively as follows: positive controls, Shu Min
Spraying group, butyric acid hydrocortisone group are repaired, with warm water by auris dextra wiped clean, dimethylbenzene 0.03mL is added dropwise and causes inflammation, left ear
As control, positive controls are not processed, and Shu Min repairs spraying group and sprays Shu Min reparation on mouse right ear by spraying, butyric acid hydrogen
Change cortisone group and smear butyric acid hydrocortisone on mouse right ear, cervical dislocation puts to death mouse after 30min, and it is double to cut mouse immediately
Exterior feature of picking up the ears is laid round auricle in two auricle same areas, is weighed with assay balance with the punch of diameter 8mm.So that scorching ear
The weight of piece (right side) subtracts the difference for not causing scorching auricle (left side) weight, the index as the mouse auricle swelling degree.Calculate swelling
And compare the difference between three groups.Swelling calculation formula is as follows:
Swelling=auris dextra weight-left ear weight
Using the test mice auricle swelling experiment of above-mentioned experimental method, the experimental result of acquisition is shown in Table two:
Table two: mouse auricle swelling test result.
| Mice auricle swelling mean value (Mg) | Mice auricle swelling mean value (Mg) |
| Positive controls | 64.3 |
| Shu Min repairs spraying group | 27.8 |
| Butyric acid hydrocortisone group | 18.6 |
Thus, it is possible to find out Shu Min in the present invention repair the effect in terms of being sprayed at anti-inflammatory reached butyric acid hydrogenation can
The 80% of pine, and the anti-inflammatory effects applied to the anti-inflammatory product in terms of cosmetics of similar product are only capable of reaching butyric acid tixocortol
60%.
(2) the antipruritic experiment of histamine human body
Volunteer 90 with skin allergy are chosen, men and women half-and-half, is randomly divided into three groups, and every group of 30 volunteers divide
Not Wei control group, Shu Min repairs spraying group and dipotassium glycyrrhizinate (Dipotassium glycyrrhizinate) group, control group exist
Affected part sprays pure water；It is spraying that Shu Min repairs Shu Min reparation of the spraying group in the affected part spraying present invention；Dipotassium glycyrrhizinate group exists
The aqueous solution that affected part spraying is configured using dipotassium glycyrrhizinate (0.1%) evaluates three groups of volunteers before use, use respectively
Body itch degree after 1min, 5min, 30min and 60min.Evaluation criteria are as follows: the itch degree before test is 4 points, test
Itch degree afterwards with the itch degree before testing for referring to scoring, specific test result is as follows table three:
Table three: the antipruritic experimental result of histamine human body.
By above-mentioned experimental data, it can be concluded that, it is more independent than dipotassium glycyrrhizinate to repair spraying antipruritic effect by Shu Min in the present invention
The antipruritic effect used will be got well, therefore, it can be deduced that the various composition in the present invention has synergistic effect.
In conclusion the Shu Min in the present invention repairs the spraying mechanism according to skin allergic reaction, by between each component
Mutually synergistic effect is realized anti-inflammatory, sensitive skin of releiving, enhancing skin resistance comprehensively, and is finally realized to sensitive skin
Radical cure, effect is obviously quick, without side-effects to body, will not lower the resistance of the body, in addition, Shu Min reparation be by spraying by
Plant extracts is deployed, hormone-free, more have repairing effect to impaired skin, promotes the abatement and wound of scytitis
Healing.It is simple that Shu Min in the present invention repairs spraying preparation process, operation easy to produce, at low cost, wants to equipment without special
It asks.
For those skilled in the art, it is various corresponding that other can be made according to above technical scheme and design
Change and deformation, and all these change and modification all should belong within the scope of protection of the claims of the present invention.
Claims (8)
1. a kind of Shu Min repairs spraying, it is characterised in that: the Shu Min repairs the parts by weight of spraying component and each component are as follows: group
A:0.01-5 parts of part, B:0.05-4 parts of component, component C: 0.1-15 parts, glycyrrhetate: 0.05-4 parts, water: 80-100 parts.
2. Shu Min according to claim 1 repairs spraying, it is characterised in that: the Shu Min repairs spraying component and each component
Parts by weight are as follows: A:0.1-2 parts of component, B:0.1-1 parts of component, component C: 1-10 parts, glycyrrhetate: 0.1-1 parts, water: 85-
99 parts.
3. Shu Min according to claim 1 repairs spraying, it is characterised in that: the component A is chitosan oligosaccharide, carboxymethyl is de-
Chitosan, chitinous oligomers, carboxymethyl chitosan, in chitin any one or it is two kinds or any two or more any
Mixture.
4. Shu Min according to claim 1 repairs spraying, it is characterised in that: the component B is extracted selected from planktonic organism
One or both of object, peony root extractive.
5. Shu Min according to claim 1 repairs spraying, it is characterised in that: the component C is selected from wormwood hydrosol, smokes clothing
Careless hydrosol, chamomile hydrosol, any one or any two kinds or any two or more mixture in balm hydrosol.
6. Shu Min according to claim 1 repairs spraying, it is characterised in that: the Shu Min is repaired also to be contained by spraying
0.01-3 parts of preservative.
7. Shu Min according to claim 1 repairs spraying, it is characterised in that: the glycyrrhetate be ammonium glycyrrhizinate,
Glycyrrhizic acid list potassium, diammonium glycyrrhizinate, dipotassium glycyrrhizinate, dipotassium glycyrrhizinate, in disodium glycyrrhizinate any one or it is any two kinds or
Any two or more mixture.
8. a kind of Shu Min repairs spraying production method, it is characterised in that: method includes the following steps:
Step A: water being added into reaction vessel, and component A is added into water, heats and is stirred, at this point, heating temperature is
75-85 DEG C, mixing speed 50-80rpm/min obtains preliminary mixed liquor；
Step B: carrying out vacuum homogeneous for preliminary mixed liquor obtained in step A and be stirred, incorporation time 1-15min, this
When, vacuum degree is -0.03MPa to -0.04MPa, and mixing speed 2000-4000rpm/min, constant temperature is quiet after the mixing of vacuum homogeneous
15-30min is set, obtains standing liquid；
Step C: the temperature of the standing liquid in step B is down to 40-50 DEG C, component B, component C and glycyrrhetate is sequentially added, stirs
Mix mixing, mixing speed 30-40rpm/min；
Step D: the pH value of mixed liquor obtained in detecting step C, it is qualified when pH value is 3.5-5.5 and discharge, raw material is filtered,
Filtrate is obtained, product is made.
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