CN109254167A - A kind of automated stool analyzer - Google Patents
A kind of automated stool analyzer Download PDFInfo
- Publication number
- CN109254167A CN109254167A CN201811280272.6A CN201811280272A CN109254167A CN 109254167 A CN109254167 A CN 109254167A CN 201811280272 A CN201811280272 A CN 201811280272A CN 109254167 A CN109254167 A CN 109254167A
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- China
- Prior art keywords
- slide
- card
- folder
- motor
- push jack
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
Abstract
The present invention provides a kind of automated stool analyzer, including passing in and out model machine structure, Te Jian mechanism, slide transport mechanism, manipulator mechanism, cleaning case, microscope mechanism, disengaging model machine structure " Contraband " shape open at one end that includes is into sample output passage, specimen holder is put into sample intake passage, automatically into detection zone, special check reagent card is sent into special inspection reaction zone by Te Jian mechanism, slide is sent to and applies section by slide transport mechanism, Riker mount inspection area, spy's inspection reaction zone, section is applied within the scope of manipulator Y-direction operational stroke, manipulator completes automatic sampling in Y-direction and Z-direction, the sample pre-treatment overall process of automatic smear, then slide is sent to microscopy under microscope by slide transport mechanism, finally obtain three-in-one picture and text report, the close contact for making operator completely avoid and defecate using the above structure, the comfort level of sense organ obtains pole in checkout procedure Big to improve, operational safety and repeatability are greatly reinforced, and provide most direct foundation for clinical diagnosis.
Description
Technical field
The invention belongs to health care clinical testing techniques fields.More particularly to a kind of automated stool analyzer.
Background technique
Stool for routine inspection is one of clinical three big routine inspection projects.Stomach and intestine can be relatively intuitively understood by this inspection
The some pathological phenomenons in road, judge indirectly alimentary canal, pancreas, liver and gallbladder function status, to many diseases, especially alimentary canal disease
The diagnosis of disease and parasitic disease and curative effect monitoring all have important clinical meaning.Due to the complexity and morphology of stool sample
The particularity of inspection, the smell of sample, color, form bring the discomfort on many sense organs to operator in addition, and stool checks
Project is usually abandoned by people.With the fast development of medical level, gradually appears some stool examination quasi-instruments and replace behaviour by hand
Make.
Stool examination core is exactly morphological examination, and morphological examination requires appearance test and biology microscope to sample
Microscopy is tested.The clinical test method that health ministry is promulgated has made clear and unified regulation to its method of inspection.The present invention is just
With national " clinical examination operating instruction " for guidance, with instrument replace being accomplished manually stool for routine, occult blood test and excrement its
The stool examination instrument of its colloidal gold test.
Summary of the invention
In order to overcome the deficiencies of the prior art, the purpose of the present invention is to provide a kind of automated stool analyzers, by excrement
Just sample carry out automatic batch sample introduction, transmit slide automatically, automatic smear, automatically scanning, auto-focusing, automatic microscopy are taken pictures,
Automated image analysis processing etc. reduces pathogenic infection, improves Laboratory biosafety to improve stool examination the degree of automation
The purpose of.
To achieve the goals above, the present invention provides a kind of automated stool analyzer, including disengaging model machine structure, special inspection machine
Structure, slide transport mechanism, manipulator mechanism, cleaning case, microscope mechanism, disengaging model machine structure " Contraband " shape open at one end that includes into
Sample output passage, specimen holder are put into the right sample intake passage, and Y-direction sample introduction push jack refers to that folder and its driving device are transported by Y-direction push jack motor
It is dynamic, the Y-direction push jack motor driving wheel is moved, Y-direction push jack synchronous belt and Y-direction push jack motor driven wheel, Y-direction push jack is driven to refer to
Folder link block is fixed on the Y-direction push jack synchronous belt, and is moved therewith along Y-direction push jack slide direction, and Y-direction push jack refers to that folder passes through
Y-direction push jack refers to folder fixing piece connection, and the Y-direction push jack refers to that folder is pierced by into two exhausting hole diameters on sample output passage, along specimen holder
Specimen holder b is pushed into instrument by side.
Further, the Te Jian mechanism includes special inspection card storage device, spy's inspection card mobile module, special inspection card lifting module and
Automatic fortune card supporting element；The automatic fortune card supporting element has built upper layer and lower layer structure, is fixed on automatic fortune block plate, left
Side is fixed with special inspection cartridge body frame, in the special inspection cartridge body frame of the special inspection box insertion equipped with special inspection card, the automatic fortune block
It is equipped with occult blood card camera fixed plate on the right side of plate, is fixed with camera below, is transported automatically below the automatic fortune card supporting element
It is fixed with automatic fortune card motor on card bottom plate to connect with automatic fortune card driving wheel, automatic card synchronous belt of transporting is by the automatic fortune card master
Driving wheel is linked up with automatic fortune card driven wheel, and block form is fixed on the automatic fortune card synchronous belt pushes away card connection automatically
Plate, the card connecting plate lower end that pushes away automatically are connect with automatic fortune card sliding rail, described automatic to push away card connecting plate upper end and be fixed with automatically
Elevating screw motor is fixed with automatic card feed on the screw rod of the automatic lifting lead screw motor and refers to folder, the automatic fortune block plate
Refer to that several are evenly distributed on folder refers to for placing the card feed locating slot of detection card, the automatic card feed with the automatic card feed
It is higher than the automatic fortune block plate when folder rises and is located on the inside of the automatic fortune block plate, it is described to push away card connecting plate two sides automatically
It is fixed with automatic lifting sliding rail；Described to push away card connecting plate two sides automatically and automatic fortune card refers to folder connection, automatic lifting sliding block is fixed
The automatic lifting sliding rail and the automatic fortune card are referred to that folder connects by plate, and when detection, X refers to folder and its driving device to push jack
By X to push jack motor movement, move X to push jack motor driving wheel, drive X to push jack synchronous belt and X to push jack motor from
Driving wheel, X refer to that folder is fixed on the X on push jack synchronous belt by link block to push jack, and transport therewith along X to push jack slide direction
Dynamic, by any working position of the specimen holder push-in X into stroke, the X refers to that direction when folder push jack limits to push jack, backspace zero-bit
When, referred to the effect pressed from both sides in screw around spring to push jack by the X is fixed on, so that the X is referred to that folder twists to push jack, avoid obstacle
Object；After having inspected, when specimen holder shifts the Y-direction leftmost side onto, Y-direction goes out after sample photoelectricity receives signal, Y-direction go out sample push jack refer to folder and its
Driving device is moved by Y-direction push jack lead screw motor, is driven Y-direction slice to refer to that folder goes out sample sliding rail along Y-direction and moves, is released sample
Frame.
Further, the slide transport mechanism includes slide box, slide box base, slide channel, pushes away slide and refer to folder, described
Slide box box body side limits and is open, and the long side two sides of slide box box body lower end are respectively equipped with slide outlet and slide
Mouth is pushed away, the slide outlet is opposite with the position that the slide pushes away mouth and has limit, and slide channel is to be located at slide to transmit bottom plate
Upper similar " L " type grooved tracks, including X, to slide channel and Y-direction slide channel, the X is to slide channel on grooved tracks edge
The parallel groove in middle part direction, slide transmission bottom plate side are fixed with X and refer to folder to slide is pushed away, pass through, and push away slide one end position
In the parallel groove, X is set to refer to folder lower than slide of the X on slide channel to slide is pushed away, the X refers to folder to slide is pushed away
With X to pushing away the synchronous band connection of slide, is moved along X to slide sliding rail is pushed away under slide motor driven in X to pushing away, slide is transmitted to institute
It states on microscope mechanism objective table.
Further, there are two exhausting hole diameters in Y-direction slide channel, and Y-direction pushes away slide and refers to that folder protrusion passes through two rows of lead to
Aperture, it is living that the Y-direction pushes away the screw rod that slide refers to that the Y-direction being clipped in below the fixed slide transmission bottom plate pushes away in slide lead screw motor
Dynamic connection, and push away slide sliding rail along Y-direction and move, shift the slide onto smear position.
Further, the manipulator mechanism robot device includes building on gantry by manipulator link block, described
Pump motor and manipulator Z-direction lead screw motor are fixed on manipulator link block, the lead screw motor link block is fixed on described
On the screw rod of manipulator Z-direction lead screw motor, lead screw motor link block side is fixedly connected with agitator tank, the other side and machinery
Hand Z-direction sliding rail is flexibly connected, and gyratory agitation device is equipped in the agitator tank, and hollow sampling probe passes through the agitator tank and rotation
Agitating device connection, the hollow sampling probe top are fixedly connected by water pipe with the pump motor, below the agitator tank
It is fixed with steel needle, the hollow sampling probe and the steel needle central point are two neighboring Riker mount central point.
Further, the gantry two sides are respectively fixed with manipulator sliding rail, and the manipulator link block is fixed on two machines
On tool hand Y-direction sliding rail, manipulator Y-direction motor drives manipulator Y-direction timing belt to move along the manipulator Y-direction sliding rail, the machine
Tool hand link block rectangular structure is integrally moved along Y-direction.
Further, the microscope mechanism includes high low power lens automatic transfer equipment, motorized subject table device, fine tuning dress
It sets；The high low power lens automatic transfer equipment fixes one high low power lens conversion electricity beside the micro- lens head on A-frame
Machine, the high low power lens conversion motor are connect with microscope synchronous belt driving gear, and high low power lens conversion synchronization band passes through described
Synchronous belt driving gear is fixedly connected with microscope lens converter；The micromatic setting includes fine tuning motor, fine tuning motor master
Driving wheel, fine tuning motor driven wheel, described fine tuning motor one end are connect with Microscope base, and the other end and the fine tuning motor are driven
Wheel be flexibly connected, the fine tuning motor driven wheel with cover the fine tuning motor driven wheel close-fitting on microscope vernier knob
It closes.
Further, the motorized subject table device further includes glass frame channel, objective table, objective table linkage, described
Glass frame channel is set to the objective table upper surface, and the objective table linkage, institute are vertically fixed in the objective table side
State objective table linkage further include objective table linkage block, microscope X to motor, X to driving wheel, Y-direction motor, Y-direction driving wheel,
X is fixedly connected to driving wheel to motor and the X and links in the objective table to driven wheel and Y-direction driven wheel, the microscope X
Block lower half portion, the Y-direction motor and the Y-direction driving wheel are fastened on the objective table linkage block top half, described
Objective table linkage side passes perpendicularly through the X and is fixedly connected to driven wheel with the Y-direction driven wheel, and the X is to driving wheel
With the X to driven wheel tight fit, the image transmitting that microscope camera will acquire is to display screen.
Further, the cleaning case is fixed on Te Jian mechanism side, and top taps into the mouth of a river, and lower part picks out the mouth of a river, main
It is used to that waste water to be discharged.
Compared to the prior art, a kind of automated stool analyzer of the present invention uses above-mentioned technical proposal, reaches
Following technical effect: the present invention is by passing in and out model machine structure, Te Jian mechanism, slide transport mechanism, manipulator mechanism, cleaning case, showing
MicromilTor device, for " Contraband " shape open at one end that disengaging model machine structure includes into sample output passage, specimen holder is put into the right sample intake passage, sample
Automatic sample conveying, manipulator carry out pre-treatment to sample, then carry out smear and special inspection experiment, then smear is sent under microscope and examines
It looks into, microscope automatically scanning, auto-focusing, automatic lock image, selectivity leave and take photo information, image result is automatically analyzed,
Excrement Neo-Confucianism index, microscopy image, the special inspection three-in-one picture and text survey report of result are provided.Completely avoid operator and greatly
Just close contact, the comfort level of sense organ is greatly improved in checkout procedure, operational safety and repeatability greatly plus
By force, most direct foundation is provided for clinical diagnosis.
Detailed description of the invention
Present invention will be further explained below with reference to the attached drawings and examples:
Fig. 1 is complete machine structure schematic isometric of the invention.
Fig. 2 is disengaging model machine structure plan structure schematic isometric in Fig. 1.
Fig. 3 is that Y-direction sample introduction push jack refers to folder and its partially schematic perspective view of driving device in Fig. 2.
Fig. 4 is that X to push jack refers to folder and its driving device partial structurtes schematic isometric in Fig. 2.
Fig. 5 is that Y-direction goes out sample push jack and refers to folder and its partially schematic perspective view of driving device in Fig. 2.
Fig. 6 is Tu1Zhong Tejian mechanism plan structure schematic isometric.
Fig. 7 is special inspection card lifting moving module partial structurtes schematic isometric in Fig. 6.
Fig. 8 is slide transport mechanism plan structure schematic isometric in Fig. 1.
Fig. 9 is that slide transport mechanism looks up structural representation perspective view in Fig. 1.
Figure 10 is glass frame structural representation perspective view in Fig. 8.
Figure 11 is manipulator mechanism plan structure schematic isometric in Fig. 1.
Figure 12 is cleaning case plan structure schematic isometric in Fig. 1.
Figure 13 is Tu1Zhong microscope mechanism plan structure schematic isometric.
Figure 14 is Tu1Zhong microscope mechanism side view structural representation perspective view.
Figure 15 is microscope partial structurtes schematic isometric in Figure 13.
In figure: 1, disengaging model machine structure, 2, Te Jian mechanism, 3, slide transport mechanism, 4, manipulator mechanism, 5, cleaning case, 6,
Microscope mechanism, 1.1, X to push jack refer to folder, 1.2, Y-direction push jack refer to folder, 1.3, Y-direction slice refer to folder, 2.1, automatic fortune card support
Part, 3.2, slide box base, 3.3, slide box, 3.4, X is to slide channel, 3.5, Y-direction slide channel, 3.6, slide, 3.7, glass
Piece transmission bottom plate, 4.1, gantry, 4.3, pump motor, 5.1, water inlet, 5.2, water outlet, 6.4, microscope camera,
1.1.1, X is to push jack motor, and 1.1.2, X are to push jack sliding rail, and to push jack motor driven wheel, 1.1.4, X are synchronous to push jack by 1.1.3, X
Band, to push jack motor driving wheel, 1.2.1, Y-direction push jack refer to folder fixing piece, 1.2.2, Y-direction push jack sliding rail, 1.2.3, Y by 1.1.5, X
To push jack motor driven wheel, 1.2.4, Y-direction push jack motor, 1.2.5, Y-direction push jack motor driving wheel, 1.2.6, Y-direction push jack are synchronous
Band, 1.2.7, Y-direction push jack refer to folder link block, and 1.3.1, Y-direction push jack lead screw motor, 1.3.2, Y-direction go out sample sliding rail, 1.3.3, Y-direction
Sample photoelectricity out, 2.2.1, automatic fortune block plate, 2.2.2, special inspection cartridge body frame, 2.2.3, special inspection box, 2.2.4, the camera shooting of occult blood card
Head fixed plate, 2.3.1, automatic fortune card motor, 2.3.2, automatic fortune card driving wheel, 2.3.3, automatic fortune card synchronous belt, 2.3.4,
Automatically card driven wheel is transported, 2.3.5, pushes away card connecting plate automatically, 2.3.7,2.3.6, automatic fortune card sliding rail transport card bottom plate automatically,
2.3.9, fortune card refers to that folder, 2.4.1, automatic lifting lead screw motor, 2.4.2, automatic card feed refer to folder automatically, and 2.4.3, automatic lifting are sliding
Rail, 2.4.4, automatic lifting sliding block fixed plate, 3.4.1, parallel groove, 3.4.2, X refer to folder to pushing away slide, and 3.4.3, X are to pushing away glass
Piece motor, to pushing away slide sliding rail, 3.5.1, Y-direction push away slide and refer to folder by 3.4.5, X, and 3.5.2, Y-direction push away slide lead screw motor, 3.5.3,
Y-direction pushes away slide sliding rail, 4.2.1, manipulator link block, 4.2.2, manipulator Z-direction lead screw motor, 4.2.3, agitator tank, 4.2.4,
Lead screw motor link block, 4.2.5, hollow sampling probe, 4.2.6, steel needle, 4.2.7, manipulator Z-direction sliding rail, 4.2.8, screw rod,
4.3.1, manipulator sliding rail, 4.3.2, manipulator Y-direction motor, 4.3.3, manipulator Y-direction timing belt, 6.1.1, A-frame,
6.1.2, high low power lens conversion motor, 6.1.3, synchronous belt driving gear, 6.1.4, high low power lens conversion synchronization band are 6.2.1, micro-
Adjust motor, 6.2.2, fine tuning motor driving wheel, 6.2.3, fine tuning motor driven wheel, 6.3.1, glass frame channel, 6.3.2, loading
Platform, 6.3.3, objective table linkage block, 6.3.4, microscope X are to motor, and 6.3.5, X are to driving wheel, 6.3.6, Y-direction motor,
6.3.7, Y-direction driving wheel, 6.3.8, X are to driven wheel, 6.3.9, Y-direction driven wheel.
Specific embodiment
Further to illustrate the technical means and efficacy of the invention taken to reach above-mentioned purpose, below in conjunction with attached drawing
And preferred embodiment, a specific embodiment of the invention, structure, feature and its effect describe in detail bright.
It should be appreciated that specific embodiment described in the invention is only used to explain the present invention, it is not used to limit this hair
It is bright.
As described in Fig. 1~15, a kind of automated stool analyzer, including disengaging model machine structure 1, Te Jian mechanism 2, slide conveyer
Structure 3, manipulator mechanism 4, cleaning case 5, microscope mechanism 6, " Contraband " the shape open at one end disengaging sample that disengaging model machine structure 1 includes are logical
Road, specimen holder are put into the right sample intake passage, and Y-direction sample introduction push jack refers to that folder and its driving device are transported by Y-direction push jack motor 1.2.4
It is dynamic, the Y-direction push jack motor driving wheel 1.2.5 is moved, Y-direction push jack synchronous belt 1.2.6 and Y-direction push jack motor driven wheel are driven
1.2.3, Y-direction push jack refers to that folder link block 1.2.7 is fixed on the Y-direction push jack synchronous belt 1.2.6, and sliding along Y-direction push jack therewith
The movement of the direction rail 1.2.2, Y-direction push jack refer to that folder 1.2 refers to folder fixing piece 1.2.1 connection by Y-direction push jack, and the Y-direction push jack refers to folder
1.2 are pierced by into two exhausting hole diameters on sample output passage, and specimen holder is pushed into instrument along specimen holder side；When detection, X is to push jack
Refer to that folder and its driving device moves to push jack motor 1.1.1 by X, move X to push jack motor driving wheel 1.1.5, drive X to
Push jack synchronous belt 1.1.4 and X refers to that folder 1.1 is fixed on X to push jack by link block to push jack motor driven wheel 1.1.3, X to push jack
It on synchronous belt 1.1.4, and is moved therewith along X to the direction push jack sliding rail 1.1.2, by any work of the specimen holder push-in X into stroke
Make position.X refers to that direction when 1.1 push jack of folder limits to push jack, when backspace zero-bit, be fixed on X to push jack refer in 1.1 screws of folder around
The effect of spring allows X to refer to that folder 1.1 twists to push jack, avoiding obstacles；After having inspected, when to shift Y-direction onto most left for specimen holder
Side, Y-direction go out after sample photoelectricity 1.3.3 receives signal, and Y-direction goes out sample push jack and refers to that folder and its driving device pass through Y-direction push jack lead screw motor
1.3.1 it moves, drives Y-direction slice to refer to that folder 1.3 goes out sample sliding rail 1.3.2 along Y-direction and moves, release specimen holder.
In preferred embodiment of the present invention, referring to Fig.1, shown in 5,6,7, Te Jian mechanism 2 includes special inspection card storage device,
Spy's inspection card lifting moving module；Automatic fortune card supporting element 2.1 in the special inspection card lifting moving module has built upper layer and lower layer
Structure is fixed on automatic fortune block plate 2.2.1, and left side is fixed with special inspection cartridge body frame 2.2.2, the special inspection equipped with special inspection card
In the box 2.2.3 insertion special inspection cartridge body frame 2.2.2, occult blood card camera is equipped on the right side of the automatic fortune block plate 2.2.1
Fixed plate 2.2.4 is fixed with camera below, and the automatic fortune card supporting element 2.1 is automatic below to be transported on card bottom plate 2.3.7 admittedly
There is automatic fortune card motor 2.3.1 to connect with automatic fortune card driving wheel 2.3.2, the automatic card synchronous belt 2.3.3 that transports will be described automatic surely
Fortune card driving wheel 2.3.2 is linked up with automatic fortune card driven wheel 2.3.4, the side of being fixed on the automatic fortune card synchronous belt 2.3.3
Frame shape pushes away card connecting plate 2.3.5 automatically, and the card lower end connecting plate 2.3.5 that pushes away automatically connects with automatic fortune card sliding rail 2.3.6
It connects, the upper end card connecting plate 2.3.5 that pushes away automatically is fixed with automatic lifting lead screw motor 2.4.1, the automatic lifting screw rod electricity
Automatic card feed is fixed on the screw rod 4.2.8 of machine 2.4.1 to refer to folder 2.4.2, the automatic fortune block plate 2.2.1 and described send automatically
Card refers to that several are evenly distributed on folder 2.4.2 refers to folder 2.4.2 for placing the card feed locating slot of detection card, the automatic card feed
It is higher than the automatic fortune block plate 2.2.1 when rise and is located on the inside of the automatic fortune block plate 2.2.1, it is described to push away card company automatically
The two sides fishplate bar 2.3.5 are fixed with automatic lifting sliding rail 2.4.3；Automatically the card two sides connecting plate 2.3.5 that push away refer to automatic fortune card
2.3.9 connection is pressed from both sides, the automatic lifting sliding rail 2.4.3 and the automatic fortune card are referred to folder by automatic lifting sliding block fixed plate 2.4.4
2.3.9 connecting.
In preferred embodiment of the present invention, referring to Fig. 7, shown in 8,9,15, slide transport mechanism 3 include slide box 3.3,
Slide box base 3.2, slide channel push away slide and refer to folder, and the 3.3 box body side of slide box limits and is open, the slide box
The long side two sides of 3.3 box body lower ends are respectively equipped with slide outlet and slide pushes away mouth, and the slide outlet pushes away mouth with the slide
Position it is opposite and have limit, slide channel is to be located at similar " L " type grooved tracks on slide transmission bottom plate 3.7, including X is to glass
Piece channel 3.4 and Y-direction slide channel 3.5, the X is to slide channel 3.4 in grooved tracks along the parallel groove in middle part direction
3.4.1, slide transmission 3.7 side of bottom plate is fixed with X and refers to folder 3.4.2 to slide is pushed away, and passes through, push away slide one end be located at it is described
In parallel groove 3.4.1, make X to push away slide refer to folder 3.4.2 lower than slide 3.6 of the X on slide channel 3.4, the X to
It pushes away slide and refers to folder 3.4.2 and X to pushing away the synchronous band connection of slide, in X to pushing away under slide motor 3.4.3 driving along X to pushing away slide cunning
Rail 3.4.5 movement, slide is transmitted on 6 objective table of microscope mechanism.
In preferred embodiment of the present invention, referring to Fig. 2, shown in 6,8, there are two exhausting holes in Y-direction slide channel 3.5
Diameter, Y-direction push away slide and refer to that folder 3.5.1 protrusion passes through two exhausting hole diameters, and the Y-direction pushes away slide and refers to folder 3.5.1 in the fixation slide
The Y-direction of 3.7 lower section of transmission bottom plate pushes away the flexible connection of the screw rod 4.2.8 on slide lead screw motor 3.5.2, and pushes away slide along Y-direction and slide
Rail 3.5.3 movement shifts the slide 3.6 onto smear position, and 4 robot device of manipulator mechanism is connected by manipulator
Block 4.2.1 includes building on gantry 4.1, is fixed with pump motor 4.3 and manipulator Z on the manipulator link block 4.2.1
To lead screw motor 4.2.2, the lead screw motor link block 4.2.4 is fixed on the screw rod of the manipulator Z-direction lead screw motor 4.2.2
4.2.8 on, the side lead screw motor link block 4.2.4 is fixedly connected with agitator tank 4.2.3, and the other side and manipulator Z-direction are sliding
Rail 4.2.7 is flexibly connected, and gyratory agitation device is equipped in the agitator tank 4.2.3, and hollow sampling probe 4.2.5 passes through the stirring
Case 4.2.3 is connect with gyratory agitation device, and the top hollow sampling probe 4.2.5 is solid by water pipe and the pump motor 4.3
Fixed connection, the lower section agitator tank 4.2.3 are fixed with steel needle 4.2.6, the hollow sampling probe 4.2.5 and the steel needle 4.2.6
Central point is two neighboring Riker mount central point.
In preferred embodiment of the present invention, referring to Fig. 3, shown in 10,11,12,4.1 two sides of gantry are respectively fixed with machinery
Rubber sleeve rail 4.3.1, manipulator link block 4.2.1 are fixed on two manipulator Y-direction sliding rail 4.3.1, manipulator Y-direction motor
4.3.2 manipulator Y-direction timing belt 4.3.3 is driven to move along the manipulator Y-direction sliding rail 4.3.1, the manipulator link block
4.2.1 rectangular structure is integrally moved along Y-direction, and the microscope mechanism 6 includes high low power lens automatic transfer equipment, motorized subject table
Device, micromatic setting；The high low power lens automatic transfer equipment fixes one on A-frame 6.1.1 beside the micro- lens head
High low power lens conversion motor 6.1.2, the high low power lens conversion motor 6.1.2 and microscope synchronous belt driving gear 6.1.3 connect
It connects, high low power lens conversion synchronization band 6.1.4 connects by the way that the synchronous belt driving gear 6.1.3 and microscope lens converter are fixed
It connects；The micromatic setting includes fine tuning motor 6.2.1, fine tuning motor driving wheel 6.2.2, finely tunes motor driven wheel 6.2.3, described
Fine tuning one end motor 6.2.1 is connect with Microscope base, and the other end is flexibly connected with the fine tuning motor driven wheel 6.2.3, institute
It states fine tuning motor driven wheel 6.2.3 and covers the fine tuning motor driven wheel 6.2.3 tight fit on microscope vernier knob.
In preferred embodiment of the present invention, referring to Fig.1 0,15, shown, motorized subject table device further includes that glass frame is logical
Road 6.3.1, objective table 6.3.2, objective table linkage, glass frame channel 6.3.1 are set to the upper end the objective table 6.3.2
Face, the objective table 6.3.2 vertically fix side the objective table linkage, and the objective table linkage further includes loading
Platform linkage block 6.3.3, microscope X are to motor 6.3.4, X to driving wheel 6.3.5, Y-direction motor 6.3.6, Y-direction driving wheel 6.3.7, X
To driven wheel 6.3.8 and Y-direction driven wheel 6.3.9, the microscope X is fixedly connected to motor 6.3.4 and X to driving wheel 6.3.5
In the lower half portion objective table linkage block 6.3.3, Y-direction motor 6.3.6 and the Y-direction driving wheel 6.3.7 are fastened on load
Object platform linkage block 6.3.3 top half, the X are fixed on objective table to driven wheel 6.3.8 and the Y-direction driven wheel 6.3.9
In the vertical columns of linkage side, space is saved, the two is independent of each other by different bearing controls.The X is to driving wheel
6.3.5 with the X to driven wheel 6.3.8 tight fit, the image transmitting that microscope camera 6.4 will acquire is described to display screen
Cleaning case 5 is fixed on 2 side of Te Jian mechanism, and top taps into the mouth of a river 5.1, and lower part picks out the mouth of a river 5.2, and it is useless to be mainly used for discharge
Water.
Concrete operating principle:
(1) pass in and out sample process: the specimen holder for being loaded with sample enters instrument with along the right Y-direction sample intake passage, and sample introduction photoelectricity is opened
Pass senses specimen holder and provides signal, and X refers to that specimen holder is sent to detection zone by folder 1.1 to push jack, i.e. X carries out item on slideway
Code scanning and sample Neo-Confucianism index are taken pictures, and then hollow sampling probe is handled and sampled to sample, and X refers to folder to push jack after the completion
1.1 push away specimen holder toward Y-direction sample output passage, and sample optoelectronic switch senses specimen holder and provides signal out, and Y-direction push jack refers to folder 1.2
Specimen holder is gone out into sample prescription to release along Y-direction.
Slide 3.6 is fitted into slide box 3.3, slide box is then inserted into slide box base 3.2, Y-direction pushes away slide and refers to folder
3.5.1 it is to be checked slide to be pushed into painting section along Y-direction slide channel 3.5；After the completion of smear, X refers to that folder 3.4.2 will be to be checked to slide is pushed away
Slide pushes microslide frame channel to slide channel 3.4 along X and waits microscopy.After the completion of slide microscopy, objective table linkage dress
It sets adjustment X, Y-direction position to return to zero, slide is pushed into recycling bins.
Te Jian mechanism can place a variety of special inspection cards by different special inspection boxes.When detection, instrument is according to selected special inspection item
Mesh determines that special inspection sticks into sample.Spy's inspection card is released in turn to be fallen on automatic fortune block plate 2.2.1, automatic lifting lead screw motor
2.4.1 it rises, automatic fortune card is driven to refer to that folder 2.4.2 rises, spy's inspection card falls in automatic fortune card and refers on folder 2.4.2, then automatic fortune
Card motor 2.3.1 operation drives fortune mechanism for card one card slot of advance.It and so on completes forward to stick into sample to sample out from spy's inspection.
(2) smear and special inspection process:
Hollow sampling probe 4.2.5 insertion has been pierced through in the Riker mount of pad pasting, and dilution is added, then 360 degree rotation and upper
Lower movement is stirred, and sucks a certain amount of sample after mixing sample, and sample is then injected special inspection card reagent adding hole and slide is recessed
In slot.After hollow sampling probe 4.2.5 completes a sample, insertion cleaning case washing prepares next sample after the completion of to be cleaned
Smear.
(3) microscopy process:
Microscope carrier device can control slide X mobile to, Y-direction, by movement, can be observed under microscope different
The visual field, each visual field pass through microscope micromatic setting auto-focusing, if desired high low power lens switching, operation control software.
In microscopy picture real-time display to display, microscope ocular visual results can also be passed through.One fixed number of instrument automatic collection
Amount field-of-view image is analyzed, and carries out primary dcreening operation to result, finally audits confirmation result by reviewer.
(4) survey report:
Present invention facilitates stool examination standardization, automation, intelligence, generation Neo-Confucianism, microscopy, spy examine three-in-one picture and text
Report, greatly improves working efficiency, shortens report time, decline the labor intensity of operator, not only can guarantee
The health of operator, improves inspection quality and Laboratory biosafety rank, and for clinical laboratory information system (LIS) and
Good basis is laid in full laboratory automation (TLA).
The present invention provides a kind of automated stool analyzer, and the present invention passes through disengaging model machine structure, Te Jian mechanism, slide conveyer
Structure, manipulator mechanism, cleaning case, microscope mechanism, disengaging model machine structure " Contraband " shape open at one end that includes is into sample output passage, sample
Frame is put into the right sample intake passage, and Y-direction sample introduction push jack refers to folder and its driving device by Y-direction push jack motor movement, and microscope is automatic
Scanning, auto-focusing, automatic lock image, selectivity leave and take photo information, automatically analyze image result, provide excrement Neo-Confucianism and refer to
Mark, microscopy image, the special inspection three-in-one picture and text survey report of result.The short distance for making operator completely avoid and defecate connects
It touches, the comfort level of sense organ is greatly improved in checkout procedure, and operational safety and repeatability are greatly reinforced, for clinical diagnosis
Most direct foundation is provided.
The above embodiments are only the preferred technical solution of the present invention, and are not construed as limitation of the invention, this hair
Bright protection scope should be with the technical solution of claim record, technical characteristic in the technical solution recorded including claim
Equivalents are protection scope.Equivalent replacement i.e. within this range is improved, also within protection scope of the present invention.
Claims (9)
1. a kind of automated stool analyzer, it is characterised in that: including passing in and out model machine structure (1), Te Jian mechanism (2), slide conveyer
Structure (3), manipulator mechanism (4), cleaning case (5), microscope mechanism (6), " Contraband " shape open at one end that disengaging model machine structure (1) includes
Into sample output passage, specimen holder is put into the right sample intake passage, and Y-direction sample introduction push jack refers to that folder and its driving device pass through Y-direction push jack motor
(1.2.4) movement, moves the Y-direction push jack motor driving wheel (1.2.5), drives Y-direction push jack synchronous belt (1.2.6) and Y-direction
Push jack motor driven wheel (1.2.3), Y-direction push jack refer to that folder link block (1.2.7) is fixed on the Y-direction push jack synchronous belt (1.2.6)
On, and moved therewith along the Y-direction push jack sliding rail direction (1.2.2), Y-direction push jack refers to that folder (1.2) refers to folder fixing piece by Y-direction push jack
(1.2.1) connection, the Y-direction push jack refer to that folder (1.2) is pierced by into two exhausting hole diameters on sample output passage, will along specimen holder side
Specimen holder is pushed into instrument, and when detection, X refers to that folder and its driving device are moved by X to push jack motor (1.1.1) to push jack, make X to
Push jack motor driving wheel (1.1.5) movement drives X to push jack synchronous belt (1.1.4) and X to push jack motor driven wheel (1.1.3),
X refers to that folder (1.1) is fixed on the X on push jack synchronous belt (1.1.4) by link block to push jack, and sliding to push jack along X therewith
The movement of the rail direction (1.1.2), by any working position of the specimen holder push-in X into stroke, the X refers to folder (1.1) push jack to push jack
When direction limit, when backspace zero-bit, referred to the interior effect around spring of folder (1.1) screw to push jack by the X is fixed on, make the X
Refer to that folder (1.1) can twist to push jack, avoiding obstacles；After having inspected, when specimen holder shifts the Y-direction leftmost side onto, Y-direction goes out sample light
After electric (1.3.3) receives signal, Y-direction goes out sample push jack and refers to that folder and its driving device are transported by Y-direction push jack lead screw motor (1.3.1)
It is dynamic, it drives Y-direction slice to refer to that folder (1.3) goes out sample sliding rail (1.3.2) movement along Y-direction, releases specimen holder.
2. a kind of automated stool analyzer according to claim 1, it is characterised in that: the Te Jian mechanism (2) includes spy
Examine card storage device, spy's inspection card mobile module, special inspection card lifting module and automatic fortune card supporting element (2.1)；The automatic fortune card
Supporting element (2.1) has built upper layer and lower layer structure, is fixed on automatic fortune block plate (2.2.1), and left side is fixed with special inspection card
Box body frame (2.2.2), special inspection box (2.2.3) equipped with spy's inspection card is inserted into special inspection cartridge body frame (2.2.2), described automatic
It transports and is equipped with occult blood card camera fixed plate (2.2.4) on the right side of block plate (2.2.1), be fixed with camera below, it is described automatic
Transporting card supporting element (2.1), automatic transport is fixed with automatic fortune card motor (2.3.1) and transports card master automatically below on card bottom plate (2.3.7)
Driving wheel (2.3.2) connection, it is automatic transport card synchronous belt (2.3.3) will the automatic fortune card driving wheel (2.3.2) and automatic fortune block from
Driving wheel (2.3.4) links up, and block form is fixed on the automatic fortune card synchronous belt (2.3.3) pushes away card connecting plate automatically
(2.3.5), the card connecting plate lower end (2.3.5) that pushes away automatically is connect with automatic fortune card sliding rail (2.3.6), described to push away card company automatically
The upper end fishplate bar (2.3.5) is fixed with automatic lifting lead screw motor (2.4.1), the silk of the automatic lifting lead screw motor (2.4.1)
It is fixed with automatic card feed on bar (4.2.8) to refer to folder (2.4.2), the automatic fortune block plate (2.2.1) and the automatic card feed refer to
It is evenly distributed with several on folder (2.4.2) and refers to folder (2.4.2) for placing the card feed locating slot of detection card, the automatic card feed
It is higher than the automatic fortune block plate (2.2.1) when rise and is located on the inside of the automatic fortune block plate (2.2.1), it is described to push away automatically
The two sides card connecting plate (2.3.5) are fixed with automatic lifting sliding rail (2.4.3)；It is described automatically push away the card connecting plate two sides (2.3.5) with
Automatic fortune card refers to that folder (2.3.9) is connected, automatic lifting sliding block fixed plate (2.4.4) by the automatic lifting sliding rail (2.4.3) and
The automatic fortune card refers to that folder (2.3.9) connects.
3. a kind of automated stool analyzer according to claim 1, it is characterised in that: slide transport mechanism (3) packet
Slide box (3.3) is included, slide box base (3.2), slide channel, slide is pushed away and refers to folder, slide box (3.3) the box body side limit
And be open, the long side two sides of slide box (3.3) the box body lower end are respectively equipped with slide outlet and slide pushes away mouth, the slide
It exports opposite with the position that the slide pushes away mouth and has limit, slide channel is to be located at " L " similar in slide transmission bottom plate (3.7)
Type grooved tracks, including X, to slide channel (3.4) and Y-direction slide channel (3.5), the X is to slide channel (3.4) in groove
Along the parallel groove (3.4.1) in middle part direction, slide transmission bottom plate (3.7) side is fixed with X and refers to folder to slide is pushed away track
(3.4.2), passes through, and pushes away slide one end and is located in the parallel groove (3.4.1), and X is made to refer to folder (3.4.2) lower than institute to slide is pushed away
Slide (3.6) of the X on slide channel (3.4) is stated, the X refers to that folder (3.4.2) and X connect to slide synchronous belt is pushed away to slide is pushed away
It connects, in X to pushing away under slide motor (3.4.3) drives along X to slide sliding rail (3.4.5) movement is pushed away, slide is transmitted to described aobvious
On micromilTor device (6) objective table.
4. a kind of automated stool analyzer according to claim 3, it is characterised in that: on Y-direction slide channel (3.5)
Equipped with there is two exhausting hole diameters, Y-direction pushes away slide and refers to that folder (3.5.1) protrusion passes through two exhausting hole diameters, and the Y-direction pushes away slide and refers to folder
The Y-direction of (3.5.1) below fixation slide transmission bottom plate (3.7) pushes away the screw rod on slide lead screw motor (3.5.2)
(4.2.8) is flexibly connected, and pushes away slide sliding rail (3.5.3) movement along Y-direction, shifts the slide (3.6) onto smear position.
5. a kind of automated stool analyzer according to claim 1, it is characterised in that: the manipulator mechanism (4) is mechanical
Arm device includes building on gantry (4.1) by manipulator link block (4.2.1), on the manipulator link block (4.2.1)
It is fixed with pump motor (4.3) and manipulator Z-direction lead screw motor (4.2.2), the lead screw motor link block (4.2.4) is fixed on
On the screw rod (4.2.8) of the manipulator Z-direction lead screw motor (4.2.2), the lead screw motor link block side (4.2.4) with stir
It mixes case (4.2.3) to be fixedly connected, the other side is flexibly connected with manipulator Z-direction sliding rail (4.2.7), in the agitator tank (4.2.3)
Equipped with gyratory agitation device, hollow sampling probe (4.2.5) passes through the agitator tank (4.2.3) and connect with gyratory agitation device, institute
It states the hollow sampling probe top (4.2.5) to be fixedly connected by water pipe with the pump motor (4.3), the agitator tank (4.2.3)
Lower section is fixed with steel needle (4.2.6), and the hollow sampling probe (4.2.5) is two neighboring with the steel needle (4.2.6) central point
Riker mount central point.
6. a kind of automated stool analyzer according to claim 5, it is characterised in that: gantry (4.1) the two sides difference
It is fixed with manipulator sliding rail (4.3.1), the manipulator link block (4.2.1) is fixed on two manipulator Y-direction sliding rails (4.3.1)
On, manipulator Y-direction motor (4.3.2) drives manipulator Y-direction timing belt (4.3.3) to transport along the manipulator Y-direction sliding rail (4.3.1)
Dynamic, manipulator link block (4.2.1) rectangular structure is integrally moved along Y-direction.
7. a kind of automated stool analyzer according to claim 1, it is characterised in that: the microscope mechanism (6) includes
High low power lens automatic transfer equipment, motorized subject table device, micromatic setting；The high low power lens automatic transfer equipment is in microscope
One high low power lens conversion motor (6.1.2), the high low power lens conversion motor are fixed on A-frame (6.1.1) beside camera lens
(6.1.2) is connect with microscope synchronous belt driving gear (6.1.3), and high low power lens conversion synchronization band (6.1.4) passes through described same
Step band driving gear (6.1.3) is fixedly connected with microscope lens converter；The micromatic setting includes fine tuning motor
(6.2.1), fine tuning motor driving wheel (6.2.2), fine tuning motor driven wheel (6.2.3), fine tuning motor one end (6.2.1) and
Microscope base connection, the other end are flexibly connected with the fine tuning motor driven wheel (6.2.3), the fine tuning motor driven wheel
(6.2.3) and cover fine tuning motor driven wheel (6.2.3) tight fit on microscope vernier knob.
8. a kind of automated stool analyzer according to claim 7, it is characterised in that: the motorized subject table device also wraps
Glass frame channel (6.3.1), objective table (6.3.2), objective table linkage are included, the glass frame channel (6.3.1) is set to
Objective table (6.3.2) upper surface, the objective table linkage is vertically fixed in objective table (6.3.2) side, described
Objective table linkage further includes objective table linkage block (6.3.3), microscope X to motor (6.3.4), X to driving wheel
(6.3.5), Y-direction motor (6.3.6), Y-direction driving wheel (6.3.7), X are to driven wheel (6.3.8) and Y-direction driven wheel (6.3.9), institute
Microscope X is stated to be fixedly connected to motor (6.3.4) and the X to driving wheel (6.3.5) in the objective table linkage block (6.3.3)
Lower half portion, the Y-direction motor (6.3.6) and the Y-direction driving wheel (6.3.7) are fastened on the objective table linkage block
(6.3.3) top half, objective table linkage side pass perpendicularly through the X to driven wheel (6.3.8) and the Y-direction from
Driving wheel (6.3.9) is fixedly connected, and the X to driving wheel (6.3.5) and the X to driven wheel (6.3.8) tight fit, take the photograph by microscope
The image transmitting that picture head (6.4) will acquire is to display screen.
9. a kind of automated stool analyzer according to claim 1, it is characterised in that: the cleaning case (5) is fixed on institute
Shu Tejian mechanism (2) side, top tap into the mouth of a river (5.1), and lower part picks out the mouth of a river (5.2), are mainly used for that waste water is discharged.
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| CN201811280272.6A CN109254167A (en) | 2018-10-30 | 2018-10-30 | A kind of automated stool analyzer |
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| CN201811280272.6A CN109254167A (en) | 2018-10-30 | 2018-10-30 | A kind of automated stool analyzer |
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| CN109900526A (en) * | 2019-03-27 | 2019-06-18 | 利多(香港)有限公司 | A kind of vertical driving mechanism, sampling apparatus and sample analyser |
| CN110045136A (en) * | 2019-05-11 | 2019-07-23 | 南京岚煜生物科技有限公司 | A kind of method of automatic sample machine and automatic sample |
| CN111551418A (en) * | 2020-04-01 | 2020-08-18 | 郑州中普医疗器械有限公司 | Slide pusher |
| CN114660308A (en) * | 2022-05-18 | 2022-06-24 | 江苏蓝鲸生物医疗科技有限公司 | Full-automatic excrement detection device and using method thereof |
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