CN109248304A - A kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain - Google Patents

A kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain Download PDF

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CN109248304A
CN109248304A CN201811432691.7A CN201811432691A CN109248304A CN 109248304 A CN109248304 A CN 109248304A CN 201811432691 A CN201811432691 A CN 201811432691A CN 109248304 A CN109248304 A CN 109248304A
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parts
radix
pharmaceutical composition
analgesic
cancer pain
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李玉春
王慧涛
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention proposes the pharmaceutical compositions that a kind of department of anesthesia is used to treat cancer pain, a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, its raw material includes following components by weight: analgesic for oral administration combines (Root of Montane Spicebush, rhizoma homalonemae, rhizoma nardostachyos, Radix Glycyrrhizae, herba lysimachiae, Radix zanthoxyli, Radix Angelicae Pubescentis, longpeduncle kadsura root) 6-8 parts, it is applied with analgesic and combines (paniculate swallowwort, dragon's blood, borneol) 6-8 parts, improve pharmaceutical composition (Radix Liriopes, pueraria lobata, Radix Notoginseng, smilax, Radix Curcumae, honey) 3-5 parts, pass through analgesic combination for oral administration, being applied with analgesic combination and conditioning pharmaceutical composition can be from for oral administration, external application and body conditioning etc. are many-sided to inhibit pain, honey in conditioning pharmaceutical composition can improve drug mouthfeel, it is easy to drink, the therapeutic effect to cancer pain can greatly be improved.

Description

A kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain
Technical field
The present invention relates to the pharmaceutical composition technical field that department of anesthesia is used to treat cancer pain, specially a kind of departments of anesthesia For treating the pharmaceutical composition of cancer pain.
Background technique
Cancer pain is generally referred to by the directly caused pain of tumour, tumor invading or pressuring neural root, nerve cord, nerve Clump or nerve, invade brain and spinal cord, can lead to serious pain in these cases.Caused by tumor therapeutic procedure Pain is also considered as cancer pain, in pain patients, because the pain of a variety of causes 50%~80% fails effectively to be controlled System, therefore, find it is a kind of cancer pain, and the drug without obvious toxic-side effects can be effectively relieved, although may be a kind of reason Wanting pursues a goal, but Chinese medicine thinks that cancer pain and phlegm stop in turbid, but existing drug can not be from for oral administration, external application and body Body conditioning etc. is many-sided to inhibit pain, for this purpose, it is proposed that a kind of department of anesthesia is used to treat the medicine group of cancer pain Close object.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the existing defects, provides a kind of department of anesthesia for treating cancer pain Pharmaceutical composition and preparation method thereof, pain can be inhibited from for oral administration, external application and body conditioning etc. are many-sided, can be with The therapeutic effect to cancer pain is greatly improved, the problems in background technique can be effectively solved.
To achieve the above object, the present invention proposes: a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, former Material includes following components by weight: analgesic for oral administration combines (Root of Montane Spicebush, rhizoma homalonemae, rhizoma nardostachyos, Radix Glycyrrhizae, herba lysimachiae, two sides Needle, Radix Angelicae Pubescentis, longpeduncle kadsura root) 6-8 parts, external application analgesic combination 6-8 parts of (paniculate swallowwort, dragon's blood, borneol), conditioning pharmaceutical composition (mountain Radix Ophiopogonis, pueraria lobata, Radix Notoginseng, smilax, Radix Curcumae, honey) 3-5 parts.
As a preferred technical solution of the present invention: the analgesic for oral administration combine its raw material by weight and include with Lower component: 5-9 parts of Root of Montane Spicebush, 3-6 parts of rhizoma homalonemae, 6-9 parts of rhizoma nardostachyos, 2-6 parts of Radix Glycyrrhizae, 3-5 parts of herba lysimachiae, 4-8 parts of Radix zanthoxyli, solely It is 2-5 parts, 3-6 parts of longpeduncle kadsura root living.
As a preferred technical solution of the present invention: the external application analgesic combine its raw material by weight and include with Lower component: 3-7 parts of paniculate swallowwort, 5-9 parts of dragon's blood, 2-6 parts of borneol.
As a preferred technical solution of the present invention: its raw material of the conditioning pharmaceutical composition includes with the following group by weight Point: 2-3 parts of Radix Liriopes, 3-7 parts of pueraria lobata, 5-7 parts of Radix Notoginseng, 4-7 parts of smilax, 2-5 parts of Radix Curcumae, 2-4 parts of honey.
It is used to treat the preparation method of the pharmaceutical composition of cancer pain: S1 the present invention also provides a kind of department of anesthesia): first Choose 5-9 parts of Root of Montane Spicebush, 3-6 parts of rhizoma homalonemae, 6-9 parts of rhizoma nardostachyos, 2-6 parts of Radix Glycyrrhizae, herba lysimachiae 3-5 in analgesic combination for oral administration Part, 4-8 parts of Radix zanthoxyli, 2-5 parts of Radix Angelicae Pubescentis, 3-6 parts of longpeduncle kadsura root use cold water soak 20 minutes or so, be then placed in medicinal cupping and endured 30-40min is boiled, filtering and removing slag obtain medical fluid and drink after the completion of infusion;
S2): choosing 3-7 parts of paniculate swallowwort being applied in analgesic combination, 5-9 parts of dragon's blood, 2-6 parts of borneol, then distinguish It is ground into powdery, paste is mixed into 2-3 parts of aqueous (30-35 DEG C) in container, is then applied at patient's pain of injury i.e. It can;
S3): choose conditioning pharmaceutical composition in 2-3 parts of Radix Liriopes, 3-7 parts of pueraria lobata, 5-7 parts of Radix Notoginseng, 4-7 parts of smilax, 2-5 parts of Radix Curcumae are placed in mesh bag, then put appropriate aqueous infusion 35-45min or so, cool to 30-40 DEG C 2-4 parts of addition honey Stirring is drunk.
Compared with prior art, the beneficial effects of the present invention are: by analgesic combination for oral administration, being applied with analgesic group It closes and conditioning pharmaceutical composition can inhibit pain from for oral administration, external application and body conditioning etc. are many-sided, improve pharmaceutical composition In honey can improve drug mouthfeel, it is easy to drink, can greatly improve the therapeutic effect to cancer pain.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with specific embodiment, to this Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not For limiting the present invention.
The present invention the following technical schemes are provided:
Embodiment one: a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, raw material include by weight with Lower component: analgesic for oral administration combines (Root of Montane Spicebush, rhizoma homalonemae, rhizoma nardostachyos, Radix Glycyrrhizae, herba lysimachiae, Radix zanthoxyli, Radix Angelicae Pubescentis, longpeduncle kadsura root) 6 Part is applied with analgesic combination 6 parts of (paniculate swallowwort, dragon's blood, borneol), conditioning pharmaceutical composition (Radix Liriopes, pueraria lobata, Radix Notoginseng, soil Fu Siberian cocklebur, Radix Curcumae, honey) 3 parts.
It includes 5 parts of following components: Root of Montane Spicebush, 3 parts of rhizoma homalonemae, rhizoma nardostachyos 6 that analgesic for oral administration, which combines its raw material by weight, Part, 2 parts of Radix Glycyrrhizae, 3 parts of herba lysimachiae, 4 parts of Radix zanthoxyli, 2 parts of Radix Angelicae Pubescentis, 3 parts of longpeduncle kadsura root.
Being applied with analgesic and combining its raw material includes following components by weight: 3 parts of paniculate swallowwort, 5 parts of dragon's blood, 2 parts of borneol.
Improve its raw material of pharmaceutical composition includes following components by weight: 2 parts of Radix Liriopes, 3 parts of pueraria lobata, 5 parts of Radix Notoginseng, soil Fu 4 parts of Siberian cocklebur, 2 parts of Radix Curcumae, 2 parts of honey.
A kind of department of anesthesia is used to treat the preparation method of the pharmaceutical composition of cancer pain, comprising the following steps:
S1): choose first 5 parts of Root of Montane Spicebush in analgesic combination for oral administration, 3 parts of rhizoma homalonemae, 6 parts of rhizoma nardostachyos, 2 parts of Radix Glycyrrhizae, 3 parts of herba lysimachiae, 4 parts of Radix zanthoxyli, 2 parts of Radix Angelicae Pubescentis, 3 parts of longpeduncle kadsura root with cold water soak 20 minutes or so, be then placed in medicinal cupping and carry out Infusion 30-40min, filtering and removing slag obtain medical fluid and drink after the completion of infusion;
S2): choosing 3 parts of paniculate swallowwort being applied in analgesic combination, 5 parts of dragon's blood, 2 parts of borneol, be then ground into respectively Powdery is mixed into paste with 2 parts of aqueous (30-35 DEG C) in container, is then applied at patient's pain of injury;
S3): choose conditioning pharmaceutical composition in 2 parts of Radix Liriopes, 3 parts of pueraria lobata, 5 parts of Radix Notoginseng, 4 parts of smilax, 2 parts of Radix Curcumae set In in mesh bag, then putting appropriate aqueous infusion 35-45min or so, cools to the 2 parts of stirrings of 30-40 DEG C of addition honey and drink.
Embodiment two: a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, raw material include by weight with Lower component: analgesic for oral administration combines (Root of Montane Spicebush, rhizoma homalonemae, rhizoma nardostachyos, Radix Glycyrrhizae, herba lysimachiae, Radix zanthoxyli, Radix Angelicae Pubescentis, longpeduncle kadsura root) 7 Part is applied with analgesic combination 7 parts of (paniculate swallowwort, dragon's blood, borneol), conditioning pharmaceutical composition (Radix Liriopes, pueraria lobata, Radix Notoginseng, soil Fu Siberian cocklebur, Radix Curcumae, honey) 4 parts.
It includes 5-9 parts of following components: Root of Montane Spicebush, 4 parts of rhizoma homalonemae, rhizoma nardostachyos that analgesic for oral administration, which combines its raw material by weight, 7 parts, 3 parts of Radix Glycyrrhizae, 4 parts of herba lysimachiae, 5 parts of Radix zanthoxyli, 4 parts of Radix Angelicae Pubescentis, 4 parts of longpeduncle kadsura root.
Being applied with analgesic and combining its raw material includes following components by weight: 4 parts of paniculate swallowwort, 6 parts of dragon's blood, 3 parts of borneol.
Improve its raw material of pharmaceutical composition includes following components by weight: 3 parts of Radix Liriopes, 4 parts of pueraria lobata, 6 parts of Radix Notoginseng, soil Fu 5 parts of Siberian cocklebur, 3 parts of Radix Curcumae, 3 parts of honey.
A kind of department of anesthesia is used to treat the preparation method of the pharmaceutical composition of cancer pain, comprising the following steps:
S1): choose first 6 parts of Root of Montane Spicebush in analgesic combination for oral administration, 4 parts of rhizoma homalonemae, 7 parts of rhizoma nardostachyos, 3 parts of Radix Glycyrrhizae, 4 parts of herba lysimachiae, 5 parts of Radix zanthoxyli, 3 parts of Radix Angelicae Pubescentis, 4 parts of longpeduncle kadsura root with cold water soak 20 minutes or so, be then placed in medicinal cupping and carry out Infusion 30-40min, filtering and removing slag obtain medical fluid and drink after the completion of infusion;
S2): choosing 4 parts of paniculate swallowwort being applied in analgesic combination, 6 parts of dragon's blood, 3 parts of borneol, be then ground into respectively Powdery is mixed into paste with 3 parts of aqueous (30-35 DEG C) in container, is then applied at patient's pain of injury;
S3): choose conditioning pharmaceutical composition in 3 parts of Radix Liriopes, 4 parts of pueraria lobata, 6 parts of Radix Notoginseng, 5 parts of smilax, 3 parts of Radix Curcumae set In in mesh bag, then putting appropriate aqueous infusion 35-45min or so, cools to the 2-4 parts of stirrings of 30-40 DEG C of addition honey and drink i.e. It can.
Embodiment three: a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, raw material include by weight with Lower component: analgesic for oral administration combines (Root of Montane Spicebush, rhizoma homalonemae, rhizoma nardostachyos, Radix Glycyrrhizae, herba lysimachiae, Radix zanthoxyli, Radix Angelicae Pubescentis, longpeduncle kadsura root) 7 Part is applied with analgesic combination 7 parts of (paniculate swallowwort, dragon's blood, borneol), conditioning pharmaceutical composition (Radix Liriopes, pueraria lobata, Radix Notoginseng, soil Fu Siberian cocklebur, Radix Curcumae, honey) 4 parts.
It includes 8 parts of following components: Root of Montane Spicebush, 5 parts of rhizoma homalonemae, rhizoma nardostachyos 8 that analgesic for oral administration, which combines its raw material by weight, Part, 5 parts of Radix Glycyrrhizae, 4 parts of herba lysimachiae, 7 parts of Radix zanthoxyli, 4 parts of Radix Angelicae Pubescentis, 5 parts of longpeduncle kadsura root.
Being applied with analgesic and combining its raw material includes following components by weight: 6 parts of paniculate swallowwort, 8 parts of dragon's blood, 5 parts of borneol.
Improve its raw material of pharmaceutical composition includes following components by weight: 3 parts of Radix Liriopes, 6 parts of pueraria lobata, 6 parts of Radix Notoginseng, soil Fu 6 parts of Siberian cocklebur, 4 parts of Radix Curcumae, 3 parts of honey.
A kind of department of anesthesia is used to treat the preparation method of the pharmaceutical composition of cancer pain, comprising the following steps:
S1): choose first 8 parts of Root of Montane Spicebush in analgesic combination for oral administration, 5 parts of rhizoma homalonemae, 8 parts of rhizoma nardostachyos, 5 parts of Radix Glycyrrhizae, 4 parts of herba lysimachiae, 7 parts of Radix zanthoxyli, 4 parts of Radix Angelicae Pubescentis, 5 parts of longpeduncle kadsura root with cold water soak 20 minutes or so, be then placed in medicinal cupping and carry out Infusion 30-40min, filtering and removing slag obtain medical fluid and drink after the completion of infusion;
S2): choosing 6 parts of paniculate swallowwort being applied in analgesic combination, 8 parts of dragon's blood, 5 parts of borneol, be then ground into respectively Powdery is mixed into paste with 3 parts of aqueous (30-35 DEG C) in container, is then applied at patient's pain of injury;
S3): choose conditioning pharmaceutical composition in 3 parts of Radix Liriopes, 6 parts of pueraria lobata, 6 parts of Radix Notoginseng, 6 parts of smilax, 4 parts of Radix Curcumae set In in mesh bag, then putting appropriate aqueous infusion 35-45min or so, cools to the 4 parts of stirrings of 30-40 DEG C of addition honey and drink.
Example IV: a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, raw material include by weight with Lower component: analgesic for oral administration combines (Root of Montane Spicebush, rhizoma homalonemae, rhizoma nardostachyos, Radix Glycyrrhizae, herba lysimachiae, Radix zanthoxyli, Radix Angelicae Pubescentis, longpeduncle kadsura root) 8 Part is applied with analgesic combination 8 parts of (paniculate swallowwort, dragon's blood, borneol), conditioning pharmaceutical composition (Radix Liriopes, pueraria lobata, Radix Notoginseng, soil Fu Siberian cocklebur, Radix Curcumae, honey) 5 parts.
It includes 9 parts of following components: Root of Montane Spicebush, 6 parts of rhizoma homalonemae, rhizoma nardostachyos 9 that analgesic for oral administration, which combines its raw material by weight, Part, 6 parts of Radix Glycyrrhizae, 5 parts of herba lysimachiae, 8 parts of Radix zanthoxyli, 5 parts of Radix Angelicae Pubescentis, 6 parts of longpeduncle kadsura root.
Being applied with analgesic and combining its raw material includes following components by weight: 7 parts of paniculate swallowwort, 9 parts of dragon's blood, 6 parts of borneol.
Improve its raw material of pharmaceutical composition includes following components by weight: 3 parts of Radix Liriopes, 7 parts of pueraria lobata, 7 parts of Radix Notoginseng, soil Fu 7 parts of Siberian cocklebur, 5 parts of Radix Curcumae, 4 parts of honey.
A kind of department of anesthesia is used to treat the preparation method of the pharmaceutical composition of cancer pain, comprising the following steps:
S1): choose first 9 parts of Root of Montane Spicebush in analgesic combination for oral administration, 6 parts of rhizoma homalonemae, 9 parts of rhizoma nardostachyos, 6 parts of Radix Glycyrrhizae, 5 parts of herba lysimachiae, 8 parts of Radix zanthoxyli, 5 parts of Radix Angelicae Pubescentis, 6 parts of longpeduncle kadsura root with cold water soak 20 minutes or so, be then placed in medicinal cupping and carry out Infusion 30-40min, filtering and removing slag obtain medical fluid and drink after the completion of infusion;
S2): choosing 7 parts of paniculate swallowwort being applied in analgesic combination, 9 parts of dragon's blood, 6 parts of borneol, be then ground into respectively Powdery is mixed into paste with 3 parts of aqueous (30-35 DEG C) in container, is then applied at patient's pain of injury;
S3): choose conditioning pharmaceutical composition in 3 parts of Radix Liriopes, 7 parts of pueraria lobata, 7 parts of Radix Notoginseng, 7 parts of smilax, 5 parts of Radix Curcumae set In in mesh bag, then putting appropriate aqueous infusion 35-45min or so, cools to the 4 parts of stirrings of 30-40 DEG C of addition honey and drink.
Patient takes external application analgesic to be applied at patient's pain of injury, and external application affected part is each primary sooner or later, is applied with 3 months;Patient Filtering and removing slag after the completion of infusion are obtained medical fluid to drink, once in the morning and once at night, are drunk 3 months, as a result as follows:
Benefit of the present invention: by analgesic combination for oral administration, be applied with analgesic combination and conditioning pharmaceutical composition can be from For oral administration, external application and body conditioning etc. are many-sided to inhibit pain, and the honey improved in pharmaceutical composition can improve drug port Sense, it is easy to drink, it can greatly improve the therapeutic effect to cancer pain
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (5)

1. a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, it is characterised in that: its raw material include by weight with Lower component: analgesic for oral administration combines (Root of Montane Spicebush, rhizoma homalonemae, rhizoma nardostachyos, Radix Glycyrrhizae, herba lysimachiae, Radix zanthoxyli, Radix Angelicae Pubescentis, longpeduncle kadsura root) 6-8 Part is applied with analgesic combination 6-8 parts of (paniculate swallowwort, dragon's blood, borneol), conditioning pharmaceutical composition (Radix Liriopes, pueraria lobata, Radix Notoginseng, soil Fu Siberian cocklebur, Radix Curcumae, honey) 3-5 parts.
2. the pharmaceutical composition that a kind of department of anesthesia according to claim 1 is used to treat cancer pain, it is characterised in that: institute Stating analgesic for oral administration and combining its raw material by weight includes 5-9 parts of following components: Root of Montane Spicebush, 3-6 parts of rhizoma homalonemae, rhizoma nardostachyos 6-9 Part, 2-6 parts of Radix Glycyrrhizae, 3-5 parts of herba lysimachiae, 4-8 parts of Radix zanthoxyli, 2-5 parts of Radix Angelicae Pubescentis, 3-6 parts of longpeduncle kadsura root.
3. the pharmaceutical composition that a kind of department of anesthesia according to claim 1 is used to treat cancer pain, it is characterised in that: institute Stating external application analgesic and combining its raw material includes following components by weight: 3-7 parts of paniculate swallowwort, 5-9 parts of dragon's blood, 2-6 parts of borneol.
4. the pharmaceutical composition that a kind of department of anesthesia according to claim 1 is used to treat cancer pain, it is characterised in that: institute State conditioning its raw material of pharmaceutical composition includes following components by weight: 2-3 parts of Radix Liriopes, 3-7 parts of pueraria lobata, 5-7 parts of Radix Notoginseng, soil Fu 4-7 parts of Siberian cocklebur, 2-5 parts of Radix Curcumae, 2-4 parts of honey.
5. the preparation method that a kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain, it is characterised in that: including following step It is rapid:
S1): choosing 5-9 parts of Root of Montane Spicebush, 3-6 parts of rhizoma homalonemae, 6-9 parts of rhizoma nardostachyos, Radix Glycyrrhizae 2-6 in analgesic combination for oral administration first Part, 3-5 parts of herba lysimachiae, 4-8 parts of Radix zanthoxyli, 2-5 parts of Radix Angelicae Pubescentis, 3-6 parts of longpeduncle kadsura root use cold water soak 20 minutes or so, be then placed in Infusion 30-40min is carried out in medicinal cupping, filtering and removing slag obtain medical fluid and drink after the completion of infusion;
S2): choosing 3-7 parts of paniculate swallowwort being applied in analgesic combination, 5-9 parts of dragon's blood, 2-6 parts of borneol, then grind respectively Powdering is mixed into paste with 2-3 parts of aqueous (30-35 DEG C) in container, is then applied at patient's pain of injury;
S3): choosing 2-3 parts of Radix Liriopes, 3-7 parts of the pueraria lobata, 5-7 parts of Radix Notoginseng, 4-7 parts of smilax, Radix Curcumae in conditioning pharmaceutical composition 2-5 parts are placed in mesh bag, then put appropriate aqueous infusion 35-45min or so, cool to 30-40 DEG C of 2-4 parts of addition honey stirrings It drinks.
CN201811432691.7A 2018-11-28 2018-11-28 A kind of department of anesthesia is used to treat the pharmaceutical composition of cancer pain Pending CN109248304A (en)

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Application publication date: 20190122