CN109248194A - A kind of essential oil composition and its preparation for treating tinea pedis - Google Patents

A kind of essential oil composition and its preparation for treating tinea pedis Download PDF

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Publication number
CN109248194A
CN109248194A CN201811343346.6A CN201811343346A CN109248194A CN 109248194 A CN109248194 A CN 109248194A CN 201811343346 A CN201811343346 A CN 201811343346A CN 109248194 A CN109248194 A CN 109248194A
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CN
China
Prior art keywords
essential oil
preparation
oil composition
tinea pedis
oil
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Pending
Application number
CN201811343346.6A
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Chinese (zh)
Inventor
朱俊峰
王广强
孙清华
张翼轸
章保华
马涛涛
谢俊芬
吴妍
张玉莲
李顾丽
徐淑丽
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Anhui Fengle Perfume Co Ltd
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Anhui Fengle Perfume Co Ltd
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Priority to CN201811343346.6A priority Critical patent/CN109248194A/en
Publication of CN109248194A publication Critical patent/CN109248194A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The present invention provides kind of an essential oil composition and its preparation for treatment tinea pedis, it is characterized by comprising following steps: (1) preparation of essential oil composition: the combined plant essential oil that steam distillation of learning from else's experience obtains, the combination foundation oil that squeezing method of learning from else's experience again obtains, stirring is lower to be uniformly mixed, it gets product, (2) preparation of essential oil composition preparation: take above-mentioned essential oil composition appropriate, biosurfactant, and cosmetics customary adjuvant is added, cream is made, ointment, liniment or finish, of the invention has significant antibacterial and itching-relieving action, it can inhibit the sprawling of tinea pedis, promote regrowing for foot skin simultaneously, with significant health-care effect, there is significant prevention and treatment effect to the tinea pedis of specific crowd, this product belongs to daily chemical products, products material is natural materials, it is environmentally protective product, have to health of masses Benefit has significant social benefit.

Description

A kind of essential oil composition and its preparation for treating tinea pedis
Technical field
The present invention relates to essential oil blending technology field, specially a kind of essential oil composition and its preparation for treating tinea pedis.
Background technique
With people's work, study, the accelerating rhythm of life, people usually ignore the maintenance to biped, more especially Easily go out the crowd of foot sweat, such as the crowd, sportsman, the crowd for liking outdoor sports, car truck man, logistics that often go on business Express delivery, food delivery personnel, underground mining staff and some Susceptible population etc., are frequently subjected to the puzzlement of " tinea pedis ".
" tinea pedis " is called tinea pedis (popular name " athlete's foot ").It is common between three or four toes, vola also may occur in which, to be deep in the small water of property Blister can gradually be fused into bleb.Because of symptom development or scratching, rotten to the corn, decortication, sepage may occur in which, even, there is purulence in bacterium infection Blister, onychomycosis etc. have certain infectiousness.
By the people that " tinea pedis " perplexs, usually treated using antibacterials, in these drugs based on antifungal drug, and It is all synthesis chemicals, and effect is general.In today of natural health environmental protection concept, people increasingly focus on natural health original The selection of material, application of especially some plant (Chinese medicine) extracts in terms for the treatment of tinea pedis.
The drug for the treatment of tinea pedis is mostly in the majority with chemicals at present, based on antifungal drug.It mainly has paste, foot-soaking powder Agent, patch etc., while also there is the preparation medicine of some plants (Chinese medicine) extract, the treatment tinea pedis effect also performed well.
A kind of " Chinese medicine composition for preventing and treating tinea pedis, the ringworm of the foot, foot sweat " of Patent No. CN201810579400 is mentioned will be yellow Cypress, rhizoma atractylodis, kuh-seng, four taste of root of Dahurain angelica composition will mix in proportion after Chinese medicine material cleaning, sunning, be ground into traditional Chinese medicine powder, external application. Achieve the purpose that prevent and treat tinea pedis, the ringworm of the foot;But several effect Chinese medicines only are selected, proportionally powdery mixing is formed by crushing Object is placed on thorax bottom, in shoes sole and upper, plays prevention and treatment foot sweat, inhibits fungi, though achieve the purpose that prevent and treat tinea pedis, the ringworm of the foot has Tinea pedis effect is prevented and treated, but application mode is bad, is not easy to widely promote and apply;
" a kind of beriberi dispelling oil and preparation method thereof " of Patent No. CN201810522544 by tea tree ethereal oil, camphor tree oil, These Chinese medicines of peppermint, spina gleditsiae, peach branch, caulis sinomenii, dalbergia wood, ramulus cinnamomi and agalloch eaglewood by " tanning, pellet frozen, again freeze concentration, Active carbon filtering, tanning, traditional Chinese medicine powder is stirred " and etc. forming, for treating tinea pedis significant effect, and treatment cycle Short, Chinese medicine preparation is without side-effects.Essential oil with after traditional Chinese medicine extraction, concentration in conjunction with traditional Chinese medicine powder by way of, formed half mobility Paste, for treating tinea pedis, but operation preparation process is cumbersome, while having powdery attachment after drug smearing, and patient is given to apply Experience make troubles.
A kind of " drug for treating athlete's foot " of Patent No. CN201310179895.5, the drug be by rhizoma polygonati, Chinese prickly ash, Drug made of the Chinese medicines such as the fruit of summer cypress, the tuber of stemona, realgar boil after being impregnated with mature vinegar.Foot or hand are suffered from immersion, have heat-clearing wind-dispelling, The effect of eliminating stasis to subdue swelling, eliminating dampness is antipruritic, removing toxic substances desinsection, has the curative effect of highly significant to the treatment of athlete's foot, which is one The vinegar and water of kind of drug extract preparation, finally add garlic juice, it is understood that vinegar itself has bactericidal effect, other garlic juice gas Taste is heavier, easily causes peculiar smell etc..
Summary of the invention
Technical problem solved by the invention is to provide a kind of essential oil composition and its preparation for treating tinea pedis, to solve The problems mentioned above in the background art.
Technical problem solved by the invention is realized using following technical scheme: a kind of essential oil composition for treating tinea pedis And its preparation, comprising the following steps:
(1) preparation of essential oil composition:
The combined plant essential oil that steam distillation of learning from else's experience obtains, then the combination foundation oil for squeezing method acquisition of learning from else's experience, in proportion Stirring is lower to be uniformly mixed to get finished product;
(2) preparation of essential oil composition preparation:
It takes appropriate above-mentioned essential oil composition, biosurfactant and cosmetics customary adjuvant is added and emulsifiable paste is made Agent, ointment, liniment.
(1) preparation of essential oil composition:
The combined plant essential oil that steam distillation of learning from else's experience obtains, then the combination foundation oil for squeezing method acquisition of learning from else's experience, in proportion Stirring is lower to be uniformly mixed to get finished product;
(2) preparation of essential oil composition preparation:
It takes above-mentioned essential oil composition appropriate and cosmetics customary adjuvant is added and finish is made.
Wherein combined plant essential oil includes: tea tree ethereal oil, Peppermint essential oil, mentha piperita oil, Rosemary Oil, fish pelargonium essence Two or more combination of oil, Lavender.
Wherein combination foundation oil includes: one or both of Sweet Almond Oil, grape seed oil, SIMMONDSIA CHINENSIS SEED OIL, rose hip oil Or more combination.
Wherein biosurfactant includes: sophorolipid, rhamnolipid, seaweed glycolipid, glyceroglycolipid, soybean lecithin, Two or more combination of flat ester, phosphatidyl-ethanolamine in algae albumen glycolipid, ornithine ester, Seeley.
Compared with prior art, the beneficial effects of the present invention are:
The present invention mainly uses plants essential oil and plant base oil, is reasonably combined, and the essential oil group for the treatment of tinea pedis is formed Object is closed, chemical synthesis substance, all plant extract components of ingredient are free of.Its composition includes the group of following essential oil and base oil It closes:
(1) essential oil: tea tree ethereal oil, Peppermint essential oil, mentha piperita oil, Rosemary Oil, Geranium Essential, lavender essence Oil.
(2) base oil: Sweet Almond Oil, grape seed oil, SIMMONDSIA CHINENSIS SEED OIL.
Products of the present invention has slight antipruritic bacteriostasis, can promote old foot skin and takes off, new foot skin growth. And application method is easy: after cleaning both feet with warm water cleaning, smearing a small amount of essential oil, preparation to foot is itched the slight trouble in place or foot Place, gently crumples, absorbs essential oil.
The present invention has the function of antipruritic, antibacterial and promotes regrowing for foot skin, solves existing for the above patent not Sufficient problem such as using it is inconvenient, smear after have the shortcomings that remain that the dregs of a decoction, production technology are complicated, smell is not pure and fresh on skin.This Invent preparation essential oil composition and its preparation, have raw material sources it is natural, extract using steam distillation extract (solvent-free), Smell is fresh, simple and elegant, using carrying is convenient, production technology is easy, tinea pedis is inhibited significantly to act on, is normally applied latter 3-5 days There is good rear effect.
Of the invention has significant antibacterial and itching-relieving action, can inhibit the sprawling of tinea pedis, while promoting foot skin again Growth has significant health-care effect, has significant prevention and treatment effect to the tinea pedis of specific crowd, this product belongs to daily use chemicals Product, products material are natural materials, are environmentally protective products, beneficial to health of masses, have significant social benefit.
Specific embodiment
In order to make implement technical means of the invention, creation characteristic, reach purpose and effect is easy to understand, tie below Specific embodiment is closed, the present invention is further explained.
Technical problem solved by the invention is realized using following technical scheme: a kind of essential oil composition for treating tinea pedis And its preparation, comprising the following steps:
The preparation of essential oil composition:
The combined plant essential oil that steam distillation of learning from else's experience obtains, then the combination foundation oil for squeezing method acquisition of learning from else's experience, under stirring It is uniformly mixed to get finished product.
The preparation of essential oil composition preparation:
Take above-mentioned essential oil composition appropriate, biosurfactant, and cosmetics customary adjuvant is added, cream is made Paste, ointment, liniment or finish.
Embodiment 1
(1) 5 parts of the tea tree ethereal oil obtained after steam distillation of learning from else's experience and 1 part of group of 4 parts of mentha piperita oil and Geranium Essential At combined plant essential oil, then 45 parts of base oils formed with 45 parts of grape seed oil of the Sweet Almond Oil that is obtained after squeezing method of learning from else's experience It is uniformly mixed up to essential oil composition;
(2) essential oil composition obtained in step 1, water, cosmetic are taken and is made of sophorolipid and rhamnolipid Biosurfactant, cream, ointment, liniment or finish is made, will it is above-mentioned made of cream, ointment, liniment And finish, it is found after aspiration smears and is sprayed to affected part 3-5 days, said preparation has mild skin affinity, and smell is pure and fresh, suppression Bacterium and antipruritic effect are obvious, have obvious antibacterial and antipruritic effect, while promoting regrowing for foot skin.
American mint essential oil has kind of a pure and fresh, strong peppermint alcohol taste, has and alleviates skin irritatin and itch, can also help light Change skin redness, there is anti-inflammatory.It can treat dermatitis, acne, ringworm, scabies and pruritus, have prevention to tan severely Curative effect, while playing the role of refrigerant skin and savory, promotion foot skin regeneration.
Fresh, the slightly pungent wooden class aromatic of tea tree ethereal oil has dense flavour of a drug, and volatilization is fast, and smell is strong, sterilizes it Effect be it is most strong in all essential oils, have good curative effect to fungal infections such as trichomonad, candida albicans, moulds.Whelk, gynaecology can be treated Inflammation, various tinea, abscess of throat, toothache, words bleb etc..
Sweet Almond Oil is faint yellow, and taste is very soft, has lubricity but very salubrious, is the base oil of neutral non-greasy, rich Containing the substances such as polybasic unsaturated fatty acid, vitamin D, E and protein can soft skin, moisturizing, specially control skin itch, it is red and swollen, Dry and pimples.
Grape seed oil is in light green or yellow green, can reduce Blood Cholesterol, prevents thrombosis, and expansion blood vessel is made With, while there is nourishing brain cell, adjust neuro vegetative effect, it effectively prevent various diseases caused by cardiovascula arteriosclerosis.
Embodiment 2
(1) 2 parts of the Rosemary Oil obtained after steam distillation of learning from else's experience and 2 parts of Geranium Essential and 1 part of Lavender The combined plant essential oil of composition, then take the 45 parts of base oils formed with 45 parts of rose hip oil of SIMMONDSIA CHINENSIS SEED OIL obtained after squeezing method It is uniformly mixed to get essential oil composition;
(2) essential oil composition obtained in step 1, water, cosmetic and by seaweed glycolipid and glyceroglycolipid, big are taken The biosurfactant of beans lecithin composition, is made cream, ointment, liniment or finish, will above-mentioned manufactured cream, Ointment, liniment and finish find that said preparation has mild skin affine after aspiration smears and is sprayed to affected part 3-5 days Power, smell is pure and fresh, and antibacterial and antipruritic effect is obvious, has obvious antibacterial and antipruritic effect, while promoting regrowing for foot skin.
The distinctive green grass cool smell of rosemary and sweet tea camphor breath;The wooden taste of camphor has penetration power, clean salubrious Feel, potent convergence, consolidation weight-reducing is wrinkle resistant, adjusts the effect of cortex;Mitigate dermohemia, edema, swelling.Anti-inflammatory is strongly killed Bacterium;It is anti-oxidant.
Geranium Essential has strong synthesis sweet taste, the compound taste of rose and peppermint.Essential oil is colourless or is in light green, smell Sweet tea and it is slightly raw, be somewhat like rose, be also commonly used for manufacturing the middle taste of women perfume, can relieve pain, restrain antibacterial, put in and knit scar, increasing Strong cytophylaxis function, energy deep layer clean skin, balances sebum secretion, promotes Skin Cell newborn, repairs scar, striae of pregnancy, spy Not Shi Yongyu oily skin and small pox skin, to small pox and acne print have well alleviate and eradicating efficacy.
Embodiment 3
(1) 1 part of 2 parts of the mentha piperita oil obtained after steam distillation of learning from else's experience, 2 parts of Rosemary Oil and Geranium Essential group The combined plant essential oil of conjunction, then the 45 parts of base oils formed with 45 parts of SIMMONDSIA CHINENSIS SEED OIL of grape seed oil obtained after squeezing method of learning from else's experience stir It mixes and is uniformly mixed to get essential oil composition;
(2) essential oil composition obtained in step 1, water, cosmetic and by algae albumen glycolipid and ornithine ester are taken Cream, ointment, liniment or finish is made in the biosurfactant of composition, will it is above-mentioned made of cream, ointment, Liniment and finish find that said preparation has mild skin affinity, and smell is clear after aspiration smears and is sprayed to affected part 3-5 days Newly, antibacterial and antipruritic effect is obvious, has obvious antibacterial and antipruritic effect, while promoting regrowing for foot skin.
Embodiment 4
(1) 3 parts of 5 parts of tea tree ethereal oil, the Rosemary Oil obtained after water intaking steam distillation is formed with 2 parts of Lavender Combined plant essential oil, then obtained after squeezing method and 45 parts of Sweet Almond Oil and the base oils stirring of 45 parts of rose hip oil compositions taken to mix It closes uniformly to get essential oil composition;
(2) essential oil composition obtained in step 1, water, cosmetic and by ester flat in Seeley and phosphatidyl second are taken The biosurfactant of hydramine composition, is made cream, ointment, liniment or finish, will above-mentioned manufactured cream, ointment Agent, liniment and finish find that said preparation has mild skin affinity, smell after aspiration smears and is sprayed to affected part 3-5 days Pure and fresh, antibacterial and antipruritic effect is obvious, has obvious antibacterial and antipruritic effect, while promoting regrowing for foot skin.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.Claimed range of the invention by appended claims and Its equivalent thereof.

Claims (5)

1. a kind of essential oil composition and its preparation for treating tinea pedis, it is characterised in that: the following steps are included:
(1) preparation of essential oil composition:
The combined plant essential oil that steam distillation of learning from else's experience obtains, then the combination foundation oil for squeezing method acquisition of learning from else's experience, are stirred in proportion It is lower to be uniformly mixed to get essential oil composition finished product;
(2) preparation of essential oil composition preparation:
Manufactured essential oil composition, biosurfactant and cosmetics customary adjuvant in above-mentioned steps (1) is taken to be made Cream, ointment, liniment.
2. a kind of essential oil composition and its preparation for treating tinea pedis, it is characterised in that: the following steps are included:
(1) preparation of essential oil composition:
The combined plant essential oil that steam distillation of learning from else's experience obtains, then the combination foundation oil for squeezing method acquisition of learning from else's experience, are stirred in proportion It is lower to be uniformly mixed to get essential oil composition finished product;
(2) preparation of essential oil composition preparation:
Take manufactured essential oil composition and cosmetics customary adjuvant in above-mentioned steps (1) that finish is made.
3. a kind of essential oil composition and its preparation for treating tinea pedis according to claim 1, it is characterised in that: wherein combine Plants essential oil includes: tea tree ethereal oil, Peppermint essential oil, mentha piperita oil, Rosemary Oil, Geranium Essential, Lavender.
4. a kind of essential oil composition and its preparation for treating tinea pedis according to claim 1, it is characterised in that: wherein combine Base oil includes: Sweet Almond Oil, grape seed oil, SIMMONDSIA CHINENSIS SEED OIL, rose hip oil.
5. a kind of essential oil composition and its preparation for treating tinea pedis according to claim 1, it is characterised in that: wherein biological Surfactant includes: sophorolipid, rhamnolipid, seaweed glycolipid, glyceroglycolipid, soybean lecithin, algae albumen glycolipid, ornithine Flat ester, phosphatidyl-ethanolamine in ester, Seeley.
CN201811343346.6A 2018-11-13 2018-11-13 A kind of essential oil composition and its preparation for treating tinea pedis Pending CN109248194A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110613823A (en) * 2019-10-21 2019-12-27 王建武 Traditional Chinese medicine composition for treating beriberi and bromhidrosis, preparation method thereof and medicine containing traditional Chinese medicine composition
CN112168726A (en) * 2020-09-29 2021-01-05 广州弘莉生物科技有限公司 Skin conditioning cream and method
CN115487224A (en) * 2021-12-03 2022-12-20 象记(上海)生物科技有限公司 External essential oil for inhibiting bacteria, relieving itching and treating beriberi and preparation method thereof
EP4009949A4 (en) * 2019-08-10 2023-08-16 Locus IP Company, LLC Olfactory delivery of therapeutic compounds to the central nervous system

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CN105708737A (en) * 2014-12-02 2016-06-29 闫战军 Tea tree essential oil foot massage oil and preparation method thereof
CN108210363A (en) * 2016-12-15 2018-06-29 闫战军 A kind of ginger and tea tree brothers massage essential oil and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN105708737A (en) * 2014-12-02 2016-06-29 闫战军 Tea tree essential oil foot massage oil and preparation method thereof
CN108210363A (en) * 2016-12-15 2018-06-29 闫战军 A kind of ginger and tea tree brothers massage essential oil and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4009949A4 (en) * 2019-08-10 2023-08-16 Locus IP Company, LLC Olfactory delivery of therapeutic compounds to the central nervous system
CN110613823A (en) * 2019-10-21 2019-12-27 王建武 Traditional Chinese medicine composition for treating beriberi and bromhidrosis, preparation method thereof and medicine containing traditional Chinese medicine composition
CN112168726A (en) * 2020-09-29 2021-01-05 广州弘莉生物科技有限公司 Skin conditioning cream and method
CN115487224A (en) * 2021-12-03 2022-12-20 象记(上海)生物科技有限公司 External essential oil for inhibiting bacteria, relieving itching and treating beriberi and preparation method thereof

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Application publication date: 20190122